id author title date pages extension mime words sentences flesch summary cache txt cord-017350-rwqaw5ii Venet, F. Monitoring Immune Dysfunction in Septic Patients: Toward Tailored Immunotherapy 2010-03-10 .txt text/plain 3966 182 36 This review will focus on the immune dysfunctions described so far in septic patients regarding monocytes and T lymphocytes (as examples of innate and adaptive immune cells) and their potential use as biomarkers on a routine standardized basis for prediction of adverse outcome or occurrence of secondary nosocomial infections and for guidance of putative immunotherapy. With that said, the down modulation of CD14 expression on monocytes after septic shock (a cell surface marker decreased during monocyte apoptosis) tends to confirm this increased apoptotic process especially because its downregulation was more pronounced in patients who were not going to survive [12] . A growing body of evidence has now confirmed that the lymphocyte-mediated immune response may be dysfunctional after severe sepsis and may play a major role in the development of a state of immunosuppression in such patients [1, 18] . ./cache/cord-017350-rwqaw5ii.txt ./txt/cord-017350-rwqaw5ii.txt