id author title date pages extension mime words sentences flesch summary cache txt cord-016237-sk1wzghx Zhang, Chen Infectious Diseases 2018-09-07 .txt text/plain 1491 96 29 Patients with life-threatening pneumonia, especially those who are immunocompromised, are more likely to undergo lung biopsy to rule out unusual infections not easily diagnosed using conventional microbiologic methods and for which treatment strategies may be different. Nocardiosis ( Fig. 4 .5) occurs almost exclusively in immunocompromised patients and is caused by a gram-positive filamentous organism (Nocardia spp.) common in soil and as normal oral microflora. Some viral infections cause unique cytopathic changes that can be identified on routinely stained sections (Figs. Fungal infections more commonly seen in immunologically intact hosts may also occur in immunocompromised patients in whom the histologic findings may be more variable. It causes disease in both immunocompetent and immunocompromised patients and may be biopsied or excised because of its tendency to form a localized lung nodule. Pneumocystis pneumonia is affiliated with highly variable histologic features and therefore should always be in the differential diagnosis of infections in immunocompromised patients. ./cache/cord-016237-sk1wzghx.txt ./txt/cord-016237-sk1wzghx.txt