id author title date pages extension mime words sentences flesch summary cache txt cord-012025-faj682bp Savioli, Felicio Coagulation profile in severe COVID-19 patients: what do we know so far? 2020 .txt text/plain 810 62 38 (7) assessed the coagulation profile and outcomes of 449 severe COVID-19 patients. (8) Moreover, a negative D-dimer test could be used for decision-making on anticoagulation therapy discontinuation in venous thromboembolism patients, however, this approach remains arguable and additional studies are required to validate this proposal. (10) The diagnosis of DIC in critically ill patients is made by standard coagulation tests, which can only determine a 5% of thrombin generation and are not suitable to discriminate patients with prothrombotic states from those with increased risk of bleeding. For the present time, we suggest that additional studies should be performed focusing on coagulation testing, to provide a better understanding of the coagulation profile in severe COVID-19 patients, improve the assessment of coagulation-related risks, and support decisions on the appropriated anticoagulation therapy. High incidence of venous thromboembolic events in anticoagulated severe COVID-19 patients Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy ./cache/cord-012025-faj682bp.txt ./txt/cord-012025-faj682bp.txt