id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-011360-1n998win	Zloto, Keren	Preoperative miRNA-208a as a Predictor of Postoperative Complications in Children with Congenital Heart Disease Undergoing Heart Surgery	2019-11-15		.txt	text/plain	3404	174	42	We had reported that the level of circulating cardiac miRNA-208a following surgery can serve as a sensitive biomarker for the postoperative course of pediatric patients with CHD undergoing heart surgery for the repair of their defect [4] . Logistic regression calculations in the group of patients with oxygen saturation levels below 90% yielded a statistically significant association between the preoperative level of miRNA-208a and the risk of developing postoperative complications: the lower the level of miRNA-208a in the patient's blood before the operation, the higher was the risk for developing cardiac complications following surgery (crude OR 1.28; 95% CI 1.02-1.60; p = 0.02). The ability of preoperative levels of miRNA-208a to predict postoperative cardiac complications in the group of patients with oxygen saturation levels below 90% was studied using an ROC curve and the AUC. Our results indeed showed that high expression levels of preoperative circulating miRNA-208a were predictive of a better postoperative outcome, as reflected by fewer complications following surgery and, accordingly, were correlated with a low Aristotle score and a shorter LOH.	./cache/cord-011360-1n998win.txt	./txt/cord-011360-1n998win.txt