id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-010141-955r29sd	Sibila, Oriol	Nonantibiotic Adjunctive Therapies for Community-Acquired Pneumonia (Corticosteroids and Beyond): Where Are We with Them?	2016-12-17		.txt	text/plain	4019	213	37	The purpose of this review is to assess the evidence related to corticosteroids and other nonantibiotic adjunctive therapies use and clinical outcomes in patients with CAP, with special interest in studies published in the last 10 years. These authors demonstrated a mortality reduction in the group treated with corticosteroids, a better modulation of systemic inflammatory response, and significant improvement in clinical endpoints, such as chest X-ray, multiple organ dysfunction syndrome severity scale, PaO 2 :FiO 2 ratio, and ICU and hospital stay. Our group demonstrated that acute administration of methylprednisolone (0.5 mg/kg/12 hours during 5 days) decrease treatment failure in a population of 120 patients with severe CAP who had high inflammatory response (defined as CRP greater than 150 mg/L on admission). Effect of corticosteroids on treatment failure among hospitalized patients with severe community-acquired pneumonia and high inflammatory response: a randomized clinical trial	./cache/cord-010141-955r29sd.txt	./txt/cord-010141-955r29sd.txt