id author title date pages extension mime words sentences flesch summary cache txt cord-006679-nhbofufv Lucarelli, G. Bone marrow transplantation for thalassemia 1993 .txt text/plain 2004 86 51 Early trials of allogeneic bone marrow transplantation (BMT) for homozygous beta-thalassemia and the analyses of results of transplantation in patients less then 16 years old have allowed us to identify three classes of risk using the criteria of degree of hepatomegaly, the degree of portal fibrosis and the quality of the chelation treatment given before the transplant. Allogeneic bone marrow transplantation has proved to be a radical form of cure in those patients with an HLA identical donor found within the family.2-3We report here our experience on 491 patients transplanted since January 1981 on the base of their categorization into three classes of risk) MATERIAL The best results in term of engraftment, toxicity and GvHD prophylaxis were obtained with the association of BU 14 rag/ kg, CY 200 mg/kg and CSA alone from day-2 as GvHD prophylaxis. ./cache/cord-006679-nhbofufv.txt ./txt/cord-006679-nhbofufv.txt