id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-031037-up0z1yaf	Edwards, David	A New Natural Defense Against Airborne Pathogens	2020-07-07		.txt	text/plain	10196	509	52	In an open-labeled randomized controlled human study of 68 subjects with common cold infections including rhinoviruses and coronaviruses, as well as enterovirus and influenza A virus, nasal delivery of 2-3% hypertonic saline 2-8 times a day (median thricea-day) significantly lowered duration of illness, as well as use of over-the-counter medications, household transmissions, and viral shedding (Ramalingam et al., 2019) . Suppression of bioaerosol by delivery of the FEND aerosol relative to placebo control occurred particularly at the high dose (see Supplemental Material for lower doses), as shown in Fig. 5a , with six of the eight subjects breathing out over the duration of 12 h post treatment, a significantly lower mean particle count per liter relative to placebo (p < 0.05). Our finding that nasal inspiration of FEND in a group of 10 healthy human subjects reduces exhaled particles between 45 and 99% by way of an aerosol too large to penetrate the lower airways (Figs 8 and 9) , suggests that the upper airways are a primary source of expired bioaerosol.	./cache/cord-031037-up0z1yaf.txt	./txt/cord-031037-up0z1yaf.txt