id author title date pages extension mime words sentences flesch summary cache txt cord-005112-9mxqwqty Zhang, Hongpeng Methods for counting particles in microfluidic applications 2009-08-20 .txt text/plain 6433 321 51 Nanopore-based methods are used for single DNA molecule analysis and the capacitance counter is useful in liquids of low electrical conductivity and in sensing the changes of cell contents. In this paper, we review the major advancement of microfluidic particle counting techniques: microfluidic resistive repulse sensors, nanopore sensors, capacitance counters, light-scattering and light-blocking detectors, fluorescent detectors, and micro particle image velocimetry (PIV) counters. The microfluidic resistive pulse technique applies the basic working principle of the Coulter counter to microchannels for counting micro-and sub-micron particles. The key advantages of the microfluidic RPS include label-free particle detection and simplicity without other peripheral complex instruments other than a simple electric circuit and a micro-or nano-scale sized channel. They coupled the RPS with laser fiber-optic fluorescence technique to demonstrate a flow cytometer LOC that is able to detect fluorescent and non-fluorescent particles simultaneously, and the RPS signal-to-noise ratio is improved significantly. ./cache/cord-005112-9mxqwqty.txt ./txt/cord-005112-9mxqwqty.txt