id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-301463-jzke8fop	Hollingsworth, T. Déirdre	Mitigation Strategies for Pandemic Influenza A: Balancing Conflicting Policy Objectives	2011-02-10		.txt	text/plain	7613	335	43	National pandemic influenza plans rarely contain clear statements of policy objectives or prioritization of potentially conflicting aims, such as minimizing mortality (depending on the severity of a pandemic) or peak prevalence or limiting the socio-economic burden of contact-reducing interventions. We use epidemiological models of influenza A to investigate how contact-reducing interventions and availability of antiviral drugs or pre-pandemic vaccines contribute to achieving particular policy objectives. Studies have shown that during the 1918-19 influenza pandemic public health control strategies and changes in population contact rates lowered transmission rates and reduced mortality and case numbers [22, 23] . In this paper we consider the effectiveness of contact-reducing interventions during the first six months after the initial cases, before a pandemic vaccine is available, and evaluate optimum interventions for a range of policy objectives or constraints, such as a limited stockpile of treatments or non-specific vaccine.	./cache/cord-301463-jzke8fop.txt	./txt/cord-301463-jzke8fop.txt