id author title date pages extension mime words sentences flesch summary cache txt cord-274332-vuupgg7i Robinson, Esther R Genomics and outbreak investigation: from sequence to consequence 2013-04-29 .txt text/plain 4548 191 34 We conclude that high-throughput sequencing approaches can make a significant contribution to the investigation of outbreaks of bacterial infection and that the integration of WGS with epidemiological investigation, diagnostic assays and antimicrobial susceptibility testing will precipitate radical changes in clinical microbiology and infectious disease epidemiology in the near future. Although we recognize that virologists pioneered the use of WGS for pathogen typing, targeting genomes small enough for WGS with traditional Sanger sequencing [21] , here we will concentrate on the application of WGS to outbreaks of bacterial infection, catalyzed by the recent arrival in the marketplace of a range of technologies that fall under the umbrella term 'high-throughput sequencing' (sometimes called 'next-generation sequencing') [22, 23] . ./cache/cord-274332-vuupgg7i.txt ./txt/cord-274332-vuupgg7i.txt