id author title date pages extension mime words sentences flesch summary cache txt cord-313413-qx6fo1x2 Cipriano, Catia Metallothionein (I+II) confers, via c-myc, immune plasticity in oldest mice: model of partial hepatectomy/liver regeneration 2003-06-19 .txt text/plain 5740 281 55 Partial hepatectomy/liver regeneration (pHx) is a good model for the study of acute and constant inflammation in ageing because of its similarity to ageing and inflammation in impaired thymic endocrine activity and peripheral immune efficiency [Natural Killer (NK) cell activity and IL-2 production] (Mocchegiani et al., 1997) as well as in enhanced corticosterone (Shimada et al., 1996) and proinflammatory cytokines (IL-6 and TNF-alpha) (Kelley-Loughnane et al., 2002) in young pHx mice 48 h after partial hepatectomy. IL-6, sIL-6R and corticosterone plasma levels increased in young and very old pHx mice at 48 h from partial hepatectomy as compared with respective sham controls (P B/0.01), with restoration on day 15 of compensatory liver growth (Table 1) . ./cache/cord-313413-qx6fo1x2.txt ./txt/cord-313413-qx6fo1x2.txt