id author title date pages extension mime words sentences flesch summary cache txt cord-017461-xw02c7u5 Kauffman, Carol A. Fungal Infections 2009-02-02 .txt text/plain 5446 294 40 Candida species are the most common cause of opportunistic fungal infections, and bloodstream infections are usually treated with fluconazole or an echinocandin antifungal agent. The endemic fungi, Histoplasma capsulatum, Coccidioides species, and Blastomyces dermatitidis, cause infection when the mold form is dispersed and inhaled from the environment in those specific areas of the country in which these organisms flourish. Amphotericin B is used for initial treatment of severe histoplasmosis, coccidioi­domycosis, and blastomycosis; itraconazole is the therapy of choice for most mild to moderate infections due to these endemic mycoses. Serious fungal infections can be separated into two major categories: The opportunistic mycoses that include candidiasis, cryptococcosis, and invasive mold infections such as aspergillosis and zygomycosis, and the endemic mycoses, which in the United States, includes histoplasmosis, blastomycosis, and coccidioidomycosis. ./cache/cord-017461-xw02c7u5.txt ./txt/cord-017461-xw02c7u5.txt