id author title date pages extension mime words sentences flesch summary cache txt cord-017062-dkw2sugl Singh, Indu Delivery Systems for Lymphatic Targeting 2013-10-08 .txt text/plain 9733 491 39 The major purpose of lymphatic targeting is to provide an effective anticancer chemotherapy to prevent the metastasis of cancer cells by accumulating the drug in the regional lymph node. Hydrophilic multiwalled carbon nanotubes (MWNTs) coated with magnetic nanoparticles (MN-MWNTs) have emerged as an effective delivery system for lymphatic targeting following subcutaneous injection of these particles into the left footpad of Sprague Dawley rats; the left popliteal lymph nodes were dyed black. In vivo study, about eight times lymph node uptake of LyP-1-NPs was seen in metastasis than that of NPs, indicated LyP-1-NP as a promising carrier for targetspecifi c drug delivery to lymphatic metastatic tumours [ 129 ] . To improve carrier retention in lymph nodes, a new method of increasing lymphatic uptake of subcutaneously injected liposome utilises the high-affi nity ligands biotin and avidin. ./cache/cord-017062-dkw2sugl.txt ./txt/cord-017062-dkw2sugl.txt