id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-259560-mmz5vn0q	Price, Sarah	Trends in time to cancer diagnosis around the period of changing national guidance on referral of symptomatic patients: A serial cross-sectional study using UK electronic healthcare records from 2006–17	2020-09-09		.txt	text/plain	3839	222	51	We also hypothesised that the difference in time to diagnosis between New-NICE and Old-NICE groups would reduce over time, as evidence on vague cancer features emerged and was translated into practice by guidance revision [2, 15] . This serial, cross-sectional, primary-care study used UK Clinical Practice Research Datalink (CPRD GOLD) with linked National Cancer Registration and Analysis Service (NCRAS, Set 15) data. Semiparametric varying-coefficient analyses were limited to cancer sites with participant numbers providing ≥90 % power at the 5 % level to detect a 14-day difference in diagnostic interval between New-NICE and Old-NICE groups. Median diagnostic intervals were longer for New-NICE than for Old-NICE participants for colorectal (70 vs 51 days), oesophageal (77 vs 55 days), and lung (139⋅5 vs 124 days) cancers; however, this difference tended to decrease or disappear over time (Fig. 3) .	./cache/cord-259560-mmz5vn0q.txt	./txt/cord-259560-mmz5vn0q.txt