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Confirmed COVID-19: Large Vessel Occlusion Associated With Coronavirus Infection date: 2020-04-21 journal: Front Neurol DOI: 10.3389/fneur.2020.00353 sha: doc_id: 346815 cord_uid: 4t4gr0jz file: cache/cord-000977-ka4261wc.json key: cord-000977-ka4261wc authors: nan title: ECR 2013 Book of Abstracts - B - Scientific Sessions date: 2013-03-07 journal: Insights Imaging DOI: 10.1007/s13244-013-0228-x sha: doc_id: 977 cord_uid: ka4261wc file: cache/cord-023353-2yoz1t6a.json key: cord-023353-2yoz1t6a authors: nan title: ABSTRACTS FROM THE 2010 EVDI ANNUAL MEETING date: 2010-12-28 journal: Vet Radiol Ultrasound DOI: 10.1111/j.1740-8261.2010.01774.x sha: doc_id: 23353 cord_uid: 2yoz1t6a file: cache/cord-014687-0am4l5ms.json key: cord-014687-0am4l5ms authors: nan title: SPR 2012 date: 2012-03-29 journal: Pediatr Radiol DOI: 10.1007/s00247-012-2356-8 sha: doc_id: 14687 cord_uid: 0am4l5ms file: cache/cord-328513-81yvcgul.json key: cord-328513-81yvcgul authors: Bellastella, Giuseppe; Maiorino, Maria Ida; Bizzarro, Antonio; Giugliano, Dario; Esposito, Katherine; Bellastella, Antonio; De Bellis, Annamaria title: Revisitation of autoimmune hypophysitis: knowledge and uncertainties on pathophysiological and clinical aspects date: 2016-08-08 journal: Pituitary DOI: 10.1007/s11102-016-0736-z sha: doc_id: 328513 cord_uid: 81yvcgul file: cache/cord-345445-9t1vebey.json key: cord-345445-9t1vebey authors: Radmanesh, Alireza; Derman, Anna; Lui, Yvonne W.; Raz, Eytan; Loh, John P.; Hagiwara, Mari; Borja, Maria J.; Zan, Elcin; Fatterpekar, Girish M. title: COVID-19–associated Diffuse Leukoencephalopathy and Microhemorrhages date: 2020-05-21 journal: Radiology DOI: 10.1148/radiol.2020202040 sha: doc_id: 345445 cord_uid: 9t1vebey file: cache/cord-015352-2d02eq3y.json key: cord-015352-2d02eq3y authors: nan title: ESPR 2017 date: 2017-04-26 journal: Pediatr Radiol DOI: 10.1007/s00247-017-3820-2 sha: doc_id: 15352 cord_uid: 2d02eq3y file: cache/cord-006870-f5w6fw6q.json key: cord-006870-f5w6fw6q authors: nan title: Abstracts Presented at the Neurocritical Care Society (NCS) 15th Annual Meeting date: 2017-09-19 journal: Neurocrit Care DOI: 10.1007/s12028-017-0465-9 sha: doc_id: 6870 cord_uid: f5w6fw6q file: cache/cord-006849-vgjz74ts.json key: cord-006849-vgjz74ts authors: nan title: 27th International Congress of the European Association for Endoscopic Surgery (EAES) Sevilla, Spain, 12–15 June 2019 date: 2019-09-13 journal: Surg Endosc DOI: 10.1007/s00464-019-07109-x sha: doc_id: 6849 cord_uid: vgjz74ts file: cache/cord-023049-fio7cjj5.json key: cord-023049-fio7cjj5 authors: nan title: 2017 Peripheral Nerve Society Meeting July 8–12, 2017 Sitges, Barcelona, Spain date: 2017-06-22 journal: J Peripher Nerv Syst DOI: 10.1111/jns.12225 sha: doc_id: 23049 cord_uid: fio7cjj5 file: cache/cord-021206-4zyqqgs0.json key: cord-021206-4zyqqgs0 authors: nan title: Scientific and Educational Exhibits date: 2007 journal: nan DOI: 10.1007/s10406-007-0215-8 sha: doc_id: 21206 cord_uid: 4zyqqgs0 file: cache/cord-021087-n4epxwn9.json key: cord-021087-n4epxwn9 authors: nan title: ECR – Final Programme: Scientific and Educational Exhibits date: 2004 journal: nan DOI: 10.1007/s10406-005-0142-5 sha: doc_id: 21087 cord_uid: n4epxwn9 file: cache/cord-015359-gf32a6f1.json key: cord-015359-gf32a6f1 authors: nan title: B scientific sessions (SS) date: 2002 journal: Eur Radiol DOI: 10.1007/s00330-002-0002-9 sha: doc_id: 15359 cord_uid: gf32a6f1 file: cache/cord-009997-oecpqf1j.json key: cord-009997-oecpqf1j authors: nan title: 2018 ASPHO ABSTRACTS date: 2018-03-31 journal: Pediatr Blood Cancer DOI: 10.1002/pbc.27057 sha: doc_id: 9997 cord_uid: oecpqf1j file: cache/cord-015354-yknwveyz.json key: cord-015354-yknwveyz authors: nan title: Abstracts_Poster presentations date: 2007-09-18 journal: Eur J Nucl Med Mol Imaging DOI: 10.1007/s00259-007-0544-9 sha: doc_id: 15354 cord_uid: yknwveyz Reading metadata file and updating bibliogrpahics === updating bibliographic database Building study carrel named keyword-mri-cord === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 73803 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 74019 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 73059 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 73102 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 73224 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 73743 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 74126 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 72439 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 74351 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 73752 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 72654 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 72506 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 73222 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 72476 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 73223 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 73900 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 73447 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 73550 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 73887 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 72350 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 73220 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === id: cord-325296-zrvykzof author: Zuhorn, Frédéric title: Parainfectious encephalitis in COVID-19: “The Claustrum Sign” date: 2020-09-03 pages: extension: .txt txt: ./txt/cord-325296-zrvykzof.txt cache: ./cache/cord-325296-zrvykzof.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 2 resourceName b'cord-325296-zrvykzof.txt' === file2bib.sh === id: cord-003095-m9hmv8c8 author: Zhang, Ya-Zhou title: Accuracy of MRI diagnosis of early osteonecrosis of the femoral head: a meta-analysis and systematic review date: 2018-07-04 pages: extension: .txt txt: ./txt/cord-003095-m9hmv8c8.txt cache: ./cache/cord-003095-m9hmv8c8.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 4 resourceName b'cord-003095-m9hmv8c8.txt' === file2bib.sh === id: cord-351440-vtf3o5ml author: Zhang, Tianshu title: COVID-19-Associated Acute Multi-infarct Encephalopathy in an Asymptomatic CADASIL Patient date: 2020-10-06 pages: extension: .txt txt: ./txt/cord-351440-vtf3o5ml.txt cache: ./cache/cord-351440-vtf3o5ml.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 3 resourceName b'cord-351440-vtf3o5ml.txt' === file2bib.sh === id: cord-012651-7bllqwh1 author: Kalidindi, Kalyan Kumar Varma title: A rare cause of neurological deterioration to complete paraplegia after surgery for thoracic myelopathy: a case report date: 2019-06-05 pages: extension: .txt txt: ./txt/cord-012651-7bllqwh1.txt cache: ./cache/cord-012651-7bllqwh1.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 3 resourceName b'cord-012651-7bllqwh1.txt' === file2bib.sh === id: cord-288158-6gicgsj8 author: Mahammedi, Abdelkader title: Imaging of Neurologic Disease in Hospitalized Patients with COVID-19: An Italian Multicenter Retrospective Observational Study date: 2020-05-21 pages: extension: .txt txt: ./txt/cord-288158-6gicgsj8.txt cache: ./cache/cord-288158-6gicgsj8.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 2 resourceName b'cord-288158-6gicgsj8.txt' === file2bib.sh === id: cord-257075-9x0530cb author: Claudi, Carolin title: A Juxta-Articular Myxoma of the Thumb A Case Report date: 2020-04-20 pages: extension: .txt txt: ./txt/cord-257075-9x0530cb.txt cache: ./cache/cord-257075-9x0530cb.txt Content-Encoding ISO-8859-1 Content-Type text/plain; charset=ISO-8859-1 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 3 resourceName b'cord-257075-9x0530cb.txt' === file2bib.sh === id: cord-272623-j5gpww9q author: Sun, Wei title: The pathogenesis of multifocal osteonecrosis date: 2016-07-11 pages: extension: .txt txt: ./txt/cord-272623-j5gpww9q.txt cache: ./cache/cord-272623-j5gpww9q.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 3 resourceName b'cord-272623-j5gpww9q.txt' === file2bib.sh === id: cord-265293-l9omunq4 author: Schönegger, Carmen Maria title: Smell and Taste Disorders in COVID-19 Patients: Objective Testing and Magnetic Resonance Imaging in Five Cases date: 2020-10-24 pages: extension: .txt txt: ./txt/cord-265293-l9omunq4.txt cache: ./cache/cord-265293-l9omunq4.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 3 resourceName b'cord-265293-l9omunq4.txt' === file2bib.sh === id: cord-345445-9t1vebey author: Radmanesh, Alireza title: COVID-19–associated Diffuse Leukoencephalopathy and Microhemorrhages date: 2020-05-21 pages: extension: .txt txt: ./txt/cord-345445-9t1vebey.txt cache: ./cache/cord-345445-9t1vebey.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 4 resourceName b'cord-345445-9t1vebey.txt' === file2bib.sh === id: cord-255240-ltatgq3e author: Kesserwani, Hassan title: Cerebral Microbleeds - To Treat or Not to Treat, That Is the Question: A Case Report With a Note on Its Radiologic Deconstruction and Therapeutic Nuances date: 2020-09-20 pages: extension: .txt txt: ./txt/cord-255240-ltatgq3e.txt cache: ./cache/cord-255240-ltatgq3e.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 2 resourceName b'cord-255240-ltatgq3e.txt' === file2bib.sh === id: cord-027730-xn12s005 author: Jlassi, Amal title: Unsupervised Method Based on Superpixel Segmentation for Corpus Callosum Parcellation in MRI Scans date: 2020-05-31 pages: extension: .txt txt: ./txt/cord-027730-xn12s005.txt cache: ./cache/cord-027730-xn12s005.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 2 resourceName b'cord-027730-xn12s005.txt' === file2bib.sh === id: cord-339759-us1spoxu author: Cornelis, I. title: Clinical presentation, diagnostic findings and outcome in dogs diagnosed withpresumptive spinal‐only meningoen‐cephalomyelitis of unknown origin date: 2017-03-07 pages: extension: .txt txt: ./txt/cord-339759-us1spoxu.txt cache: ./cache/cord-339759-us1spoxu.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 3 resourceName b'cord-339759-us1spoxu.txt' === file2bib.sh === id: cord-302862-znnlyz3y author: Lim, Peter A.C. title: Transverse Myelitis date: 2019-04-17 pages: extension: .txt txt: ./txt/cord-302862-znnlyz3y.txt cache: ./cache/cord-302862-znnlyz3y.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 3 resourceName b'cord-302862-znnlyz3y.txt' === file2bib.sh === id: cord-267110-2g6owogs author: Sharma, Suvasini title: Acute Disseminated Encephalomyelitis date: 2017-11-17 pages: extension: .txt txt: ./txt/cord-267110-2g6owogs.txt cache: ./cache/cord-267110-2g6owogs.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 3 resourceName b'cord-267110-2g6owogs.txt' === file2bib.sh === id: cord-330284-r3l6hdrk author: Gao, Min title: Machine Learning-Based Radiomics Predicting Tumor Grades and Expression of Multiple Pathologic Biomarkers in Gliomas date: 2020-09-11 pages: extension: .txt txt: ./txt/cord-330284-r3l6hdrk.txt cache: ./cache/cord-330284-r3l6hdrk.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 4 resourceName b'cord-330284-r3l6hdrk.txt' === file2bib.sh === id: cord-011990-feqqx32n author: Carminati, Marco title: Challenges for Microelectronics in Non-Invasive Medical Diagnostics date: 2020-06-29 pages: extension: .txt txt: ./txt/cord-011990-feqqx32n.txt cache: ./cache/cord-011990-feqqx32n.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 4 resourceName b'cord-011990-feqqx32n.txt' === file2bib.sh === id: cord-258556-hglp1vpm author: Peña-Solórzano, Carlos A. title: Findings from machine learning in clinical medical imaging applications – Lessons for translation to the forensic setting date: 2020-10-18 pages: extension: .txt txt: ./txt/cord-258556-hglp1vpm.txt cache: ./cache/cord-258556-hglp1vpm.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 3 resourceName b'cord-258556-hglp1vpm.txt' === file2bib.sh === id: cord-328513-81yvcgul author: Bellastella, Giuseppe title: Revisitation of autoimmune hypophysitis: knowledge and uncertainties on pathophysiological and clinical aspects date: 2016-08-08 pages: extension: .txt txt: ./txt/cord-328513-81yvcgul.txt cache: ./cache/cord-328513-81yvcgul.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 3 resourceName b'cord-328513-81yvcgul.txt' === file2bib.sh === id: cord-331268-kzy33hdb author: Lynch, Sharon G. title: Multiple sclerosis date: 1996-01-31 pages: extension: .txt txt: ./txt/cord-331268-kzy33hdb.txt cache: ./cache/cord-331268-kzy33hdb.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 4 resourceName b'cord-331268-kzy33hdb.txt' === file2bib.sh === id: cord-022594-fx044gcd author: Pirko, Istvan title: Demyelinating Disorders of the Central Nervous System date: 2009-05-18 pages: extension: .txt txt: ./txt/cord-022594-fx044gcd.txt cache: ./cache/cord-022594-fx044gcd.txt Content-Encoding ISO-8859-1 Content-Type text/plain; charset=ISO-8859-1 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 3 resourceName b'cord-022594-fx044gcd.txt' === file2bib.sh === id: cord-023353-2yoz1t6a author: nan title: ABSTRACTS FROM THE 2010 EVDI ANNUAL MEETING date: 2010-12-28 pages: extension: .txt txt: ./txt/cord-023353-2yoz1t6a.txt cache: ./cache/cord-023353-2yoz1t6a.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 5 resourceName b'cord-023353-2yoz1t6a.txt' === file2bib.sh === id: cord-323581-qtasvgtd author: Zhang, Yu-Dong title: Advances in Multimodal Data Fusion in Neuroimaging: Overview, Challenges, and Novel Orientation date: 2020-07-17 pages: extension: .txt txt: ./txt/cord-323581-qtasvgtd.txt cache: ./cache/cord-323581-qtasvgtd.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 4 resourceName b'cord-323581-qtasvgtd.txt' === file2bib.sh === id: cord-006828-i88on326 author: nan title: Abstracts DGRh-Kongress 2013 date: 2013-09-15 pages: extension: .txt txt: ./txt/cord-006828-i88on326.txt cache: ./cache/cord-006828-i88on326.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 5 resourceName b'cord-006828-i88on326.txt' === file2bib.sh === id: cord-009713-sxd4t2tz author: nan title: Poster Presentations date: 2020-01-10 pages: extension: .txt txt: ./txt/cord-009713-sxd4t2tz.txt cache: ./cache/cord-009713-sxd4t2tz.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 5 resourceName b'cord-009713-sxd4t2tz.txt' === file2bib.sh === id: cord-006869-g2q1gpp0 author: nan title: Neurocritical Care Society 7th Annual Meeting date: 2009-10-08 pages: extension: .txt txt: ./txt/cord-006869-g2q1gpp0.txt cache: ./cache/cord-006869-g2q1gpp0.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 4 resourceName b'cord-006869-g2q1gpp0.txt' === file2bib.sh === id: cord-022659-chwk2bs4 author: nan title: Abstracts: Poster session date: 2004-10-08 pages: extension: .txt txt: ./txt/cord-022659-chwk2bs4.txt cache: ./cache/cord-022659-chwk2bs4.txt Content-Encoding ISO-8859-1 Content-Type text/plain; charset=ISO-8859-1 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 4 resourceName b'cord-022659-chwk2bs4.txt' === file2bib.sh === id: cord-006876-v2m5l5wz author: nan title: Neurocritical Care Society 14(th) Annual Meeting date: 2016-08-11 pages: extension: .txt txt: ./txt/cord-006876-v2m5l5wz.txt cache: ./cache/cord-006876-v2m5l5wz.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 6 resourceName b'cord-006876-v2m5l5wz.txt' === file2bib.sh === id: cord-017031-i10q2569 author: Brix, Gunnar title: Basics of Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy date: 2008 pages: extension: .txt txt: ./txt/cord-017031-i10q2569.txt cache: ./cache/cord-017031-i10q2569.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 9 resourceName b'cord-017031-i10q2569.txt' === file2bib.sh === id: cord-015352-2d02eq3y author: nan title: ESPR 2017 date: 2017-04-26 pages: extension: .txt txt: ./txt/cord-015352-2d02eq3y.txt cache: ./cache/cord-015352-2d02eq3y.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 9 resourceName b'cord-015352-2d02eq3y.txt' === file2bib.sh === id: cord-006880-9dgmdtj8 author: nan title: Neurocritical Care Society 10th Annual Meeting: October 4 - 7, 2012 Sheraton Denver Downtown Hotel Denver, Colorado date: 2012-09-19 pages: extension: .txt txt: ./txt/cord-006880-9dgmdtj8.txt cache: ./cache/cord-006880-9dgmdtj8.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 6 resourceName b'cord-006880-9dgmdtj8.txt' === file2bib.sh === id: cord-000843-e1bn79ui author: nan title: ECR 2011 Book of Abstracts - A - Postgraduate Educational Programme date: 2011-03-01 pages: extension: .txt txt: ./txt/cord-000843-e1bn79ui.txt cache: ./cache/cord-000843-e1bn79ui.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 7 resourceName b'cord-000843-e1bn79ui.txt' === file2bib.sh === id: cord-006182-kck5e1ry author: nan title: 17th Annual Meeting, Neurocritical Care Society, October 15–18, 2019, Vancouver, Canada date: 2019-10-01 pages: extension: .txt txt: ./txt/cord-006182-kck5e1ry.txt cache: ./cache/cord-006182-kck5e1ry.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 8 resourceName b'cord-006182-kck5e1ry.txt' === file2bib.sh === id: cord-014687-0am4l5ms author: nan title: SPR 2012 date: 2012-03-29 pages: extension: .txt txt: ./txt/cord-014687-0am4l5ms.txt cache: ./cache/cord-014687-0am4l5ms.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 6 resourceName b'cord-014687-0am4l5ms.txt' === file2bib.sh === id: cord-001221-due9tloa author: nan title: ECR 2014, Part A date: 2014-02-27 pages: extension: .txt txt: ./txt/cord-001221-due9tloa.txt cache: ./cache/cord-001221-due9tloa.txt Content-Encoding ISO-8859-1 Content-Type text/plain; charset=ISO-8859-1 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 6 resourceName b'cord-001221-due9tloa.txt' === file2bib.sh === id: cord-005105-twsy61oq author: nan title: SIU 2015 Abstracts date: 2015-09-21 pages: extension: .txt txt: ./txt/cord-005105-twsy61oq.txt cache: ./cache/cord-005105-twsy61oq.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 14 resourceName b'cord-005105-twsy61oq.txt' === file2bib.sh === id: cord-006870-f5w6fw6q author: nan title: Abstracts Presented at the Neurocritical Care Society (NCS) 15th Annual Meeting date: 2017-09-19 pages: extension: .txt txt: ./txt/cord-006870-f5w6fw6q.txt cache: ./cache/cord-006870-f5w6fw6q.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 7 resourceName b'cord-006870-f5w6fw6q.txt' === file2bib.sh === id: cord-000977-ka4261wc author: nan title: ECR 2013 Book of Abstracts - B - Scientific Sessions date: 2013-03-07 pages: extension: .txt txt: ./txt/cord-000977-ka4261wc.txt cache: ./cache/cord-000977-ka4261wc.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 12 resourceName b'cord-000977-ka4261wc.txt' === file2bib.sh === id: cord-021206-4zyqqgs0 author: nan title: Scientific and Educational Exhibits date: 2007 pages: extension: .txt txt: ./txt/cord-021206-4zyqqgs0.txt cache: ./cache/cord-021206-4zyqqgs0.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 23 resourceName b'cord-021206-4zyqqgs0.txt' === file2bib.sh === id: cord-023049-fio7cjj5 author: nan title: 2017 Peripheral Nerve Society Meeting July 8–12, 2017 Sitges, Barcelona, Spain date: 2017-06-22 pages: extension: .txt txt: ./txt/cord-023049-fio7cjj5.txt cache: ./cache/cord-023049-fio7cjj5.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 14 resourceName b'cord-023049-fio7cjj5.txt' === file2bib.sh === id: cord-021087-n4epxwn9 author: nan title: ECR – Final Programme: Scientific and Educational Exhibits date: 2004 pages: extension: .txt txt: ./txt/cord-021087-n4epxwn9.txt cache: ./cache/cord-021087-n4epxwn9.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 11 resourceName b'cord-021087-n4epxwn9.txt' === file2bib.sh === id: cord-015359-gf32a6f1 author: nan title: B scientific sessions (SS) date: 2002 pages: extension: .txt txt: ./txt/cord-015359-gf32a6f1.txt cache: ./cache/cord-015359-gf32a6f1.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 26 resourceName b'cord-015359-gf32a6f1.txt' === file2bib.sh === id: cord-009997-oecpqf1j author: nan title: 2018 ASPHO ABSTRACTS date: 2018-03-31 pages: extension: .txt txt: ./txt/cord-009997-oecpqf1j.txt cache: ./cache/cord-009997-oecpqf1j.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 27 resourceName b'cord-009997-oecpqf1j.txt' === file2bib.sh === id: cord-015354-yknwveyz author: nan title: Abstracts_Poster presentations date: 2007-09-18 pages: extension: .txt txt: ./txt/cord-015354-yknwveyz.txt cache: ./cache/cord-015354-yknwveyz.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 16 resourceName b'cord-015354-yknwveyz.txt' === file2bib.sh === id: cord-006849-vgjz74ts author: nan title: 27th International Congress of the European Association for Endoscopic Surgery (EAES) Sevilla, Spain, 12–15 June 2019 date: 2019-09-13 pages: extension: .txt txt: ./txt/cord-006849-vgjz74ts.txt cache: ./cache/cord-006849-vgjz74ts.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 28 resourceName b'cord-006849-vgjz74ts.txt' Que is empty; done keyword-mri-cord === reduce.pl bib === id = cord-003095-m9hmv8c8 author = Zhang, Ya-Zhou title = Accuracy of MRI diagnosis of early osteonecrosis of the femoral head: a meta-analysis and systematic review date = 2018-07-04 pages = extension = .txt mime = text/plain words = 2734 sentences = 159 flesch = 55 summary = Heterogeneity of the included studies were reviewed to select proper effect model for pooled weighted sensitivity, specificity, and diagnostic odds ratio (DOR). RESULTS: Forty-three studies related to diagnostic accuracy of MRI to detect early osteonecrosis of the femoral head were involved in the meta-analysis. Therefore, in this paper, a systematic review and meta-analysis of all qualified studies were performed to explore the diagnosis accuracy of MRI in early ANFH. The studies that met the following criteria were included in our review: (1) prospective cohort study or cross-sectional study; (2) the research objects are patients suspected with early osteonecrosis of the femoral head without other serious diseases; (3) the studies provided the data of true positive (TP), false positive (FP), false negative (FN), and true negative (TN); and (4) the publications were only available in English and Chinese. Comparative analysis of diagnostic value of X -ray, CT and MRI in early diagnosis of avascular necrosis of femoral head cache = ./cache/cord-003095-m9hmv8c8.txt txt = ./txt/cord-003095-m9hmv8c8.txt === reduce.pl bib === id = cord-000843-e1bn79ui author = nan title = ECR 2011 Book of Abstracts - A - Postgraduate Educational Programme date = 2011-03-01 pages = extension = .txt mime = text/plain words = 91224 sentences = 4805 flesch = 41 summary = The role of radiology includes (a) characterisation of sonographically indeterminate adnexal masses, (b) staging as guidance for surgery and treatment planning (including identification of sites of non optimal resectabilty) in suspected ovarian cancer, (c) assessment of recurrent disease, and (d) in selected cases image-guided biopsy. The association of multiple markers of structural and functional imaging (MRI and PET) and the use of advanced computational analysis techniques will allow better management of AD but it needs a broader validation and know the most efficient combination of biomarkers at each stage of the disease, including the preclinical period. Although the basic techniques for DCE-CT have been available for decades, more recently a range of technological advances have contributed to the greater applicability of perfusion CT in the clinical environment including wider CT detectors, shorter gantry rotation times, 'table-toggling', radiation dose reduction and software corrections for image mis-registration due to respiratory or other patient motion. cache = ./cache/cord-000843-e1bn79ui.txt txt = ./txt/cord-000843-e1bn79ui.txt === reduce.pl bib === id = cord-001221-due9tloa author = nan title = ECR 2014, Part A date = 2014-02-27 pages = extension = .txt mime = text/plain words = 107848 sentences = 5493 flesch = 40 summary = In short: obtaining samples for making an accurate diagnosis and also to know more about its specific biology (biomarkers); IR covers any possibility needed for vascular access; percutaneous needle ablation is the best alternative in selected patients; endovascular embolisation with "vehiculisation" of therapies is an outstanding method for selective treatment, and sometimes precise ablation, of different tumors; IR is a unique way to offer palliation in a wide range of tumoral complications, such as embolisation for bleeding, stenting for vein obstructions or drainage of fluid collections. CT may be useful for osteoid osteoma and MRI is the best imaging technique for further diagnosis and staging by displaying tumour composition and extent of bone marrow involvement, including skip lesions, presence and extent of extraosseous soft tissue mass, and involvement of neurovascular bundle, muscle compartments and adjacent joint. cache = ./cache/cord-001221-due9tloa.txt txt = ./txt/cord-001221-due9tloa.txt === reduce.pl bib === id = cord-006828-i88on326 author = nan title = Abstracts DGRh-Kongress 2013 date = 2013-09-15 pages = extension = .txt mime = text/plain words = 30772 sentences = 2576 flesch = 52 summary = Comparing gene expression profiles of yellow fever immunized individuals and active SLE patients it was possible to identify a "common" and an "autoimmune-specific" IFN signature. The inflammatory and profibrotic effects upon Aab stimulation in vitro, and their associations with clinical findings suggest a role for autoantibody-mediated activation of immune cells mediated through the AT1R and ETAR in the pathogenesis or even the onset of the disease. This study was aimed to investigate the humoral and cellular immune response to VZV including assessment of IgG-anti-VZV avidity and VZV-specific reactivity of lymphocytes in RA (n=56) or JIA patients (n=75) on different treatments, including biologic agents, such as anti-tumor-necrosis-factor(TNF)-alpha or anti-interleukin-6 (IL-6) receptor inhibition (tocilizumab), compared to 37 healthy adults (HA) and 41 children (HC). Production of cytokines by B cells in response to TLR9 stimulation inversely correlates with disease activity in SLE-patients cache = ./cache/cord-006828-i88on326.txt txt = ./txt/cord-006828-i88on326.txt === reduce.pl bib === id = cord-006869-g2q1gpp0 author = nan title = Neurocritical Care Society 7th Annual Meeting date = 2009-10-08 pages = extension = .txt mime = text/plain words = 45395 sentences = 2661 flesch = 49 summary = This was a pilot study to compare the cerebral neurochemical changes in patients with traumatic brain injury (TBI) who underwent conventional blood glucose level (BGL) control and intensive BGL control with continuous titrated insulin. We studied 14 comatose SAH patients who underwent multimodality neuromonitoring with intracranial pressure (ICP), cerebral microdialysis, and brain tissue oxygen (PbtO 2 ) as part of their clinical care. We studied 46 consecutive comatose patients with subarachnoid or intracerebral hemorrhage, traumatic brain injury, or cardiac arrest who underwent cerebral microdialysis and intracranial pressure monitoring.Continuous insulin infusion was used to maintain target serum glucose levels of 80-120 mg/dl. This suggests that risk of cerebral vasospasm following traumatic brain injury is increased not only in subarachnoid hemorrhage, but also intraparenchymal hemorrhage, and that Rotterdam CT score may be a useful metric for assessing risk of csPTV in severe TBI patients. cache = ./cache/cord-006869-g2q1gpp0.txt txt = ./txt/cord-006869-g2q1gpp0.txt === reduce.pl bib === id = cord-005105-twsy61oq author = nan title = SIU 2015 Abstracts date = 2015-09-21 pages = extension = .txt mime = text/plain words = 124096 sentences = 7584 flesch = 54 summary = Th e present study is based on a retrospective analysis of a database of over 600 patients (age range 17-57 years) who met the consensus criteria for bacterial prostatitis, 75% of whom had dysuria, 35% perineal discomfort, 60% had obstructive luts, 37% infertility of unknown etiology, 10% erectile dysfunction and 25% recurrent infection of the partner. Further research is needed to determine to assess whether localization of small volume disease on 68Ga-PSMA PET/CT can improve diagnostic algorithms and outcomes in patients with recurrent PCa. Introduction and Objective: To assess long-term results of salvage pelvic lymph node dissection (PLND) in prostate cancer (PC) patients (pts) with biochemical recurrence aft er primary local treatment and confi rmed solitary lymph node (LN) metastases. cache = ./cache/cord-005105-twsy61oq.txt txt = ./txt/cord-005105-twsy61oq.txt === reduce.pl bib === id = cord-006876-v2m5l5wz author = nan title = Neurocritical Care Society 14(th) Annual Meeting date = 2016-08-11 pages = extension = .txt mime = text/plain words = 59719 sentences = 3440 flesch = 47 summary = We conducted a prospective cohort study among mild and moderate-severe TBI patients admitted to a level 1 trauma center with these inclusion criteria: 1) Age < 65 years, 2) No severe non-TBI injuries, 3) No prior cardiac disease, and 4) Minimal comorbidities. In most instances, DC has been performed based on neurosurgical evaluation of the patient with or without intracranial pressure (ICP) monitoring and evidence of increased shown variable outcomes in emergency (within 4 hours of injury) neurosurgical procedure in Traumatic Brain Injury (TBI). This is an observational cohort study of adult patients (>18 years) in a 10-bed NSICU at an academic, tertiary care center evaluating quality outcome measures pre-and post-neurointensivists. Intensivists in neuro ICU must consistently assess and treat the non-neurological complications in traumatic brain and spine-injured patients and deliver appropriate care to bring down the mortality and morbidity and improve outcome. cache = ./cache/cord-006876-v2m5l5wz.txt txt = ./txt/cord-006876-v2m5l5wz.txt === reduce.pl bib === === reduce.pl bib === id = cord-011990-feqqx32n author = Carminati, Marco title = Challenges for Microelectronics in Non-Invasive Medical Diagnostics date = 2020-06-29 pages = extension = .txt mime = text/plain words = 9004 sentences = 394 flesch = 45 summary = This paper reviews some recent results and technical challenges which still need to be addressed in terms of the design of CMOS analog application specific integrated circuits (ASICs) and their integration in the surrounding systems, in order to consolidate this technological paradigm. In multi-modal imaging, now that the compatibility of the acquisition chains (thousands of Silicon Photo-Multipliers channels) of gamma detectors with Tesla-level magnetic fields has been demonstrated, other development directions, enabled by microelectronics, can be envisioned in particular for single-photon emission tomography (SPECT): a faster and simplified operation, for instance, to allow transportable applications (bed-side) and hardware pre-processing that reduces the number of output signals and the image reconstruction time. Architecture of the gamma camera of the INSERT SPECT system: the current signals of 72 silicon photo-multiplier (SiPM) pixels are read by two ASICs [43] , featuring a low-impedance input stage, programmable shaper, peak stretcher and fast comparator to trigger the acquisition of events by the FPGA-based DAQ unit [44] . cache = ./cache/cord-011990-feqqx32n.txt txt = ./txt/cord-011990-feqqx32n.txt === reduce.pl bib === id = cord-006182-kck5e1ry author = nan title = 17th Annual Meeting, Neurocritical Care Society, October 15–18, 2019, Vancouver, Canada date = 2019-10-01 pages = extension = .txt mime = text/plain words = 87645 sentences = 4817 flesch = 46 summary = The primary objective of COGiTATE (CppOpt GuIded Therapy Assessment of Target Effectiveness) is to demonstrate feasibility of individualising CPP at CPPopt in TBI patients, expressed as the percentage of monitoring time for which CPP is within 5 mmHg of regularly updated CPPopt targets during the first 5 days of Intensive Care Unit (ICU) admission. Neurocritical care has become increasingly subspecialized.Yet, due to limited availability of dedicated Neurocritical Care units (NCCUs), often patients may need to be admitted to ICUs other than NCCUs. This survey based study was conducted to explore self-reported knowledge in recognizing and managing some common neurological emergencies such as stroke, status epilepticus, raised intracranial pressure etc among critical care nurses at a Comprehensive Stroke Center. Coagulation factor Xa (recombinant), inactivated-Xa inhibitor associated life--factor prothrombin complex concentrate (PCC) was utilized offRetrospective, single center, cohort study including adult intracranial hemorrhage patients who received discharge between efficacy (defined by International Society on Thrombosis and Haemostasis criteria), thrombotic events, ICU and hospital length of stay, and mortality. cache = ./cache/cord-006182-kck5e1ry.txt txt = ./txt/cord-006182-kck5e1ry.txt === reduce.pl bib === === reduce.pl bib === id = cord-012651-7bllqwh1 author = Kalidindi, Kalyan Kumar Varma title = A rare cause of neurological deterioration to complete paraplegia after surgery for thoracic myelopathy: a case report date = 2019-06-05 pages = extension = .txt mime = text/plain words = 2049 sentences = 127 flesch = 44 summary = title: A rare cause of neurological deterioration to complete paraplegia after surgery for thoracic myelopathy: a case report INTRODUCTION: Progressive deterioration of neurological status post-thoracic myelopathy surgery after a clinically stable period is rare and can pose a diagnostic dilemma. DISCUSSION: Ascending myelopathy is a potential but rare cause of delayed deterioration in neurological status after surgical intervention. SPAM has been described in the literature as an unusual cause of delayed neurological deterioration after traumatic spinal cord injury in cases where the deterioration could not be explained by mechanical instability, syrinx formation or therapeutic mis-intervention. This case report provides us with an insight into a potential cause akin to SPAM, which needs to be considered in a patient with progressive neurological deterioration after surgical decompression and stabilization for myelopathy. cache = ./cache/cord-012651-7bllqwh1.txt txt = ./txt/cord-012651-7bllqwh1.txt === reduce.pl bib === id = cord-006880-9dgmdtj8 author = nan title = Neurocritical Care Society 10th Annual Meeting: October 4 - 7, 2012 Sheraton Denver Downtown Hotel Denver, Colorado date = 2012-09-19 pages = extension = .txt mime = text/plain words = 82351 sentences = 4528 flesch = 49 summary = Patients initially comatose after cardiac arrest treated who awoke after therapeutic hypothermia (TH) were evaluated by a neuropsychologist prior to hospital discharge with the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS), a well-validated tool that assesses function in multiple domains compared to standardized normal values. Clinical data including the pre-admission-status, neuroradiological, initial presentation, treatment, and outcome were evaluated through institutional databases, patient's medical charts and by mailed questionnaires. To determine the differences in hospital outcomes among adult mild traumatic brain injury (TBI) patients where the severity of TBI is defined by Glasgow Coma Scale (GCS) score. Retrospective chart analysis was performed on all adult patients arriving to emergency department with history of fall at a level one trauma center for parameters like vomiting, alteration of consciousness (AOC) & loss of consciousness (LOC) after TBI; post-traumatic amnesia (PTA) and history of seizures before or after injury, along with outcomes such as ICU admission & ICU length of stay. cache = ./cache/cord-006880-9dgmdtj8.txt txt = ./txt/cord-006880-9dgmdtj8.txt === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === id = cord-022659-chwk2bs4 author = nan title = Abstracts: Poster session date = 2004-10-08 pages = extension = .txt mime = text/plain words = 49153 sentences = 2598 flesch = 49 summary = We investigated the usefulness of informant-based data in Alzheimer's disease (AD) by comparing caregivers' subjective evaluations of 83 probable A D patients' performance on an abbreviated version of the Memory Self-Report Questionnaire to objective evaluations derived from an extensive battery of neuropsychological tests and to clinicians' evaluations. Compared with 89 subjects (mean age 75.2 yr; 34 men, 55 women) with dementia of the Alzheimer type (DAT), there were no significant group differences for comparable Clinical Dementia Rating stages of dementia for measures of language, Activities of Daily Living, or general cognition. The mean age at onset did not differ significantly between handedness groups (F [ l,lOO] = .82), but the mean duration of symptoms ( Alterations in the optical properties of brain can be used to detect pathological changes in patients with Alzheimer's disease (AD). cache = ./cache/cord-022659-chwk2bs4.txt txt = ./txt/cord-022659-chwk2bs4.txt === reduce.pl bib === id = cord-272623-j5gpww9q author = Sun, Wei title = The pathogenesis of multifocal osteonecrosis date = 2016-07-11 pages = extension = .txt mime = text/plain words = 3117 sentences = 166 flesch = 55 summary = For patients with osteonecrosis of both the hip and knee joints or for patients with a history of corticosteroid use or alcohol abuse who had osteonecrosis of one or more joints in the shoulder, ankle, wrist or elbow, magnetic resonance imaging (MRI) was also performed on other joints, regardless of whether these joints were symptomatic. Of the patients with a history of corticosteroid use, 18 had SLE, nine had chronic nephropathy, five had hematological diseases (four had acute lymphoblastic leukemia and one had non-Hodgkin's lymphoma), five had an organ transplantation (four had a renal transplantation and one had a cardiac transplantation), three had Sjogren's syndrome, two had dermatomyositis, two had multiple sclerosis and three received steroid therapy for trauma emergency. 3) Patients with corticosteroid use or alcohol abuse and who are diagnosed with osteonecrosis of one or more joints in the shoulder, ankle, wrist and elbow should have their hips and knees evaluated by MRI. cache = ./cache/cord-272623-j5gpww9q.txt txt = ./txt/cord-272623-j5gpww9q.txt === reduce.pl bib === id = cord-267110-2g6owogs author = Sharma, Suvasini title = Acute Disseminated Encephalomyelitis date = 2017-11-17 pages = extension = .txt mime = text/plain words = 5206 sentences = 328 flesch = 38 summary = In patients who have a relapse, biomarkers and imaging should help differentiate multiphasic ADEM, neuromyelitis optica spectrum disorder, anti-MOG antibody–associated relapsing demyelination, and multiple sclerosis. Acute disseminated encephalomyelitis (ADEM) is an acute immune-mediated inflammatory demyelinating condition involving the brain and spinal cord, which presents clinically with new-onset polyfocal neurologic features, which by definition include encephalopathy. A third ADEM-like event is not consistent with a diagnosis of multiphasic ADEM but indicates a chronic relapsing demyelinating disorder, such as relapsing optic neuritis, neuromyelitis optica spectrum disorder associated with antiaquaporin-4 antibodies, relapsing anti-MOG antibody-associated demyelination, or MS depending the clinical phenotype, biomarker, and neuroimaging findings. A long-term follow-up study using the 2007 International Pediatrics Multiple Sclerosis Study Group criteria evaluated the parameters at initial diagnosis and eventual conversion to MS in a cohort of 123 children with a first episode of acute CNS demyelination. Multiple sclerosis and acute disseminated encephalomyelitis diagnosed in children after long-term follow-up: comparison of presenting features An adult case of anti-myelin oligodendrocyte glycoprotein (MOG) antibody-associated multiphasic acute disseminated encephalomyelitis at 33-year intervals cache = ./cache/cord-267110-2g6owogs.txt txt = ./txt/cord-267110-2g6owogs.txt === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === id = cord-022594-fx044gcd author = Pirko, Istvan title = Demyelinating Disorders of the Central Nervous System date = 2009-05-18 pages = extension = .txt mime = text/plain words = 25103 sentences = 1371 flesch = 46 summary = If a patient presents with a history of two or more attacks, but objective clinical evidence only suggests one lesion, the following additional data is needed to confirm the diagnosis: the disease process has to be disseminated in space as demonstrated by MRI; alternatively, two or more MRI-detected lesions consistent with MS plus positive CSF would suffice to meet the newly defined criteria. The EBM calculations regarding this trial show an RRR of 24%, and ARR of 11%, and an NNT of 9 patients over 2 years in order to prevent one conversion to "clinically definite MS." These two studies provide support for considering early treatment in patients presenting with first attack, in the presence of multiple asymptomatic MRI lesions, but further studies are needed to determine whether this approach will provide a prolonged benefit on disease course. cache = ./cache/cord-022594-fx044gcd.txt txt = ./txt/cord-022594-fx044gcd.txt === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === id = cord-255240-ltatgq3e author = Kesserwani, Hassan title = Cerebral Microbleeds - To Treat or Not to Treat, That Is the Question: A Case Report With a Note on Its Radiologic Deconstruction and Therapeutic Nuances date = 2020-09-20 pages = extension = .txt mime = text/plain words = 3410 sentences = 193 flesch = 52 summary = We present the case of an 86-year-old woman who has a vascular dementia, Binswanger's syndrome, and coronary artery disease, who presented with more than five CMBs. We present this case in order to highlight the dilemma of anti-platelet therapy in this group of patients and we demonstrate the cardinal radiologic features of CMBs. We then segue into the pathologic correlates of CMBs and associated risk factors. If the magnetic resonance imaging (MRI) scanner software is endowed with a left-handed reference frame such as Siemens, the CMBs appear hyperintense on the phase map. Hence one faces a therapeutic dilemma; with such extensive cerebral white matter disease and stable coronary artery disease, is anti-platelet therapy warranted in the presence of more than five CMBs? [ In the study by Lau et al., in 1811 patients who were prescribed anti-platelet therapy, the five-year risk of recurrent ischemic stroke and hemorrhagic stroke both increased with the number of CMBs [6] . cache = ./cache/cord-255240-ltatgq3e.txt txt = ./txt/cord-255240-ltatgq3e.txt === reduce.pl bib === === reduce.pl bib === id = cord-027730-xn12s005 author = Jlassi, Amal title = Unsupervised Method Based on Superpixel Segmentation for Corpus Callosum Parcellation in MRI Scans date = 2020-05-31 pages = extension = .txt mime = text/plain words = 3940 sentences = 206 flesch = 51 summary = title: Unsupervised Method Based on Superpixel Segmentation for Corpus Callosum Parcellation in MRI Scans Differently, Hofer proposed the only work based on tractography of DTI (Diffusion Tensor Imaging) by subdividing the CC into five regions from an average behavior observed via tractography in a specific population of 8 subjects [1] . On the second hand, differently to geometric parcellation methods, Rittner proposed a data-driven method based on the Watershed technique [15] . We propose a CC parcellation method based on SLIC, which is non-geometric and fully automatic superpixel segmentation technique. For the evaluation of the proposed parcellation method, we are the only study that used brain MRI scans from two public datasets. Since the Hofer and Witelson CC parcellation methods are based on geometric CC parcellation, their results did not vary among different subjects throughout the experimented dataset. cache = ./cache/cord-027730-xn12s005.txt txt = ./txt/cord-027730-xn12s005.txt === reduce.pl bib === id = cord-302862-znnlyz3y author = Lim, Peter A.C. title = Transverse Myelitis date = 2019-04-17 pages = extension = .txt mime = text/plain words = 4781 sentences = 254 flesch = 38 summary = Following the acute management, which may include use of steroids, immunosuppressive drugs, and plasma exchange, a comprehensive medical rehabilitation program is important to optimize recovery from the resultant impairments and disabilities and manage associated complications. Factors associated with poor outcomes include severe initial symptoms with spinal shock, delayed presentation to the hospital after maximum deficits have already occurred, development of syringomyelia, and extensive MRI lesions. Patients with TM may present in the ambulatory clinic, urgent care center, or hospital setting with complaints of weakness of the limbs, sensory impairments, pain, and difficulties with the bowel and bladder. The functional limitations in a patient with TM usually depend on the level of spinal cord involvement and corresponding muscles affected. Effective management of intractable neuropathic pain using an intrathecal morphine pump in a patient with acute transverse myelitis cache = ./cache/cord-302862-znnlyz3y.txt txt = ./txt/cord-302862-znnlyz3y.txt === reduce.pl bib === === reduce.pl bib === id = cord-288158-6gicgsj8 author = Mahammedi, Abdelkader title = Imaging of Neurologic Disease in Hospitalized Patients with COVID-19: An Italian Multicenter Retrospective Observational Study date = 2020-05-21 pages = extension = .txt mime = text/plain words = 1099 sentences = 76 flesch = 46 summary = title: Imaging of Neurologic Disease in Hospitalized Patients with COVID-19: An Italian Multicenter Retrospective Observational Study Of 725 consecutive hospitalized patients with coronavirus disease 2019, 108 (15%) had acute neurologic symptoms necessitating neurologic imaging. Imaging of Neurologic Disease in Hospitalized Patients with COVID-19: An Italian Multicenter Retrospective Observational Study E271 10 had acute ischemic infarcts and two had intracranial hemorrhage. The main neurologic imaging hallmark was acute ischemic infarcts, which were present in 34 of the 108 patients (31%) (30 [28%] on CT scans and four [20%] on MRI scans). Our study demonstrated that the neurologic imaging features of hospitalized patients with COVID-19 were variable, without a specific pattern but dominated by acute ischemic infarcts and intracranial hemorrhages. Currently, we have a poor mechanistic understanding of the neurologic symptoms in patients with COVID-19, whether these are arising from critical illness or from direct central nervous system invasion of severe acute respiratory syndrome coronavirus 2 (10). cache = ./cache/cord-288158-6gicgsj8.txt txt = ./txt/cord-288158-6gicgsj8.txt === reduce.pl bib === id = cord-009713-sxd4t2tz author = nan title = Poster Presentations date = 2020-01-10 pages = extension = .txt mime = text/plain words = 43950 sentences = 2945 flesch = 52 summary = Poster No. 010 Seizure, developmental and cognitive outcomes in children post hemispherotomy TT TAY 1 , DR REED 2 , VJ JOSAN 3 , SR RUST 4 , JT TAN 5 1 University of Manchester, Manchester, UK; 2 Neuropsychology Team, Paediatric Psychosocial Service, Royal Manchester Children's Hospital, Manchester, UK; 3 Neurosurgery, Salford Royal NHS Foundation, Manchester, UK; 4 Paediatric Neuropsychology, Royal Manchester Children's Hospital, Manchester, UK; 5 Paediatric Neurology, Royal Manchester Children's Hospital, Manchester, UK Introduction: Patients with focal refractory epilepsy secondary to structural hemispheric changes have been shown in retrospective studies to have significantly improved seizure outcomes following hemispheric disconnection. In a univariate analysis of 682 cases with ≥12 months follow-up data, poor final outcome (defined as modified Rankin Scale [mRS] score 3-6) occurred in 30% and was associated with very young or elderly age at onset, movement disorder, decreased consciousness, autonomic dysfunction, mechanical ventilation, higher mRS score in the acute phase, longer hospital stay, extreme delta brush on EEG, abnormal MRI, CSF pleocytosis and elevated CSF protein (all p<0.05). cache = ./cache/cord-009713-sxd4t2tz.txt txt = ./txt/cord-009713-sxd4t2tz.txt === reduce.pl bib === id = cord-330284-r3l6hdrk author = Gao, Min title = Machine Learning-Based Radiomics Predicting Tumor Grades and Expression of Multiple Pathologic Biomarkers in Gliomas date = 2020-09-11 pages = extension = .txt mime = text/plain words = 4941 sentences = 273 flesch = 51 summary = The present study aimed to use conventional machine learning algorithms to predict the tumor grades and pathologic biomarkers on magnetic resonance imaging (MRI) data. The radiomic features were extracted from enhanced MRI images, and three frequently-used machine-learning models of LC, Support Vector Machine (SVM), and Random Forests (RF) were built for four predictive tasks: (1) glioma grades, (2) Ki67 expression level, (3) GFAP expression level, and (4) S100 expression level in gliomas. CONCLUSION: The machine-learning based radiomics approach can provide a non-invasive method for the prediction of glioma grades and expression levels of multiple pathologic biomarkers, preoperatively, with favorable predictive accuracy and stability. Three machine-learning-based models (LR, SVM, and RF) were built to perform the tasks: (1) classify the glioma grades, and (2) predict the expression levels of Ki67, S100, and GFAP. The machine-learning based radiomics approach was applied to predict glioma grades and the expression levels of pathologic biomarkers Ki67, GFAP, and S100 in low or high. cache = ./cache/cord-330284-r3l6hdrk.txt txt = ./txt/cord-330284-r3l6hdrk.txt === reduce.pl bib === id = cord-325296-zrvykzof author = Zuhorn, Frédéric title = Parainfectious encephalitis in COVID-19: “The Claustrum Sign” date = 2020-09-03 pages = extension = .txt mime = text/plain words = 892 sentences = 58 flesch = 33 summary = Follow-up has been carried out four months later showing a normalization in cell count of CSF and improvement of MRI findings, although the claustrum lesions persisted. While immunological markers remained unspecific and imaging findings of acute necrotizing encephalitis were absent in our patient, brain MRI disclosed a unique pattern, a.k.a. the claustrum sign. Common MRI findings in a recent study of COVID-19 encephalopathy were cortical signal abnormalities on FLAIR images (37%), accompanied by diffusion reduction, leptomeningeal enhancement and cortical blooming artifacts in some cases. MRI findings in COVID-19 encephalitis, especially when suggesting autoimmune encephalopathy may imply therapeutic interventions, such as immunosuppressive therapy. Recently, progressive clinical improvement along with a reduction of inflammatory CSF parameters has been observed in COVID-19 encephalitis, following high-dose steroid treatment [11] . In summary, a previously undescribed imaging pattern in parainfectious COVID-19 encephalitis is presented that bears a strong resemblance to MRI findings in autoimmune encephalitic syndromes, such as known from epileptic or encephalitis caused by antineuronal antibodies. cache = ./cache/cord-325296-zrvykzof.txt txt = ./txt/cord-325296-zrvykzof.txt === reduce.pl bib === id = cord-265293-l9omunq4 author = Schönegger, Carmen Maria title = Smell and Taste Disorders in COVID-19 Patients: Objective Testing and Magnetic Resonance Imaging in Five Cases date = 2020-10-24 pages = extension = .txt mime = text/plain words = 2114 sentences = 124 flesch = 51 summary = title: Smell and Taste Disorders in COVID-19 Patients: Objective Testing and Magnetic Resonance Imaging in Five Cases Those with objectifiable alteration in taste or smell were subjected to MRI with contrast agent to investigate possible involvement of the central nervous system. We encourage medical professionals to conduct specialized examinations and MRIs in the acute stage of disease, which guarantees an optimum patient care. The study was conducted on five patients reporting impairment of taste and smell with confirmed SARS-CoV-2 infection in East Tyrol. In case objective testing revealed alterations in taste or smell, patients were subjected to MRI in a timely manner. Three weeks after the first olfactory and gustatory examination, a follow-up testing was conducted with the three patients who also had a second MRI. The first MRI images showed slight alterations in one patient, which could be associated with a SARS-CoV-2 infection. Magnetic resonance imaging alteration of the brain in a patient with coronavirus disease 2019 (COVID-19) and anosmia cache = ./cache/cord-265293-l9omunq4.txt txt = ./txt/cord-265293-l9omunq4.txt === reduce.pl bib === id = cord-351440-vtf3o5ml author = Zhang, Tianshu title = COVID-19-Associated Acute Multi-infarct Encephalopathy in an Asymptomatic CADASIL Patient date = 2020-10-06 pages = extension = .txt mime = text/plain words = 1599 sentences = 92 flesch = 47 summary = The chronological changes from the initial DWI and ADC images to the disappearance of these signals in the follow-up MRI support that the patient had acute subcortical ischemic changes or necrotic changes. The brain MRI showed multiple DWI lesions and corresponding ADC sequence changes which were consistent with multiple acute infarcts possibly related to hypoxic-ischemic injury from systemic perturbations and resultant tissue hypoxia. The distribution of the CT and MRI changes in our case is similar to a recent case report of acute hemorrhagic necrotizing encephalopathy in a COVID-19 patient [3] , which case, to our knowledge, was not tested for a pathological NOTCH3 mutation. The clinical features and CT and MRI changes are consistent with acute subcortical multiple infarctions which could be related to or provoked by a viral infection. Our described case is an atypical presentation of an acute COVID-19 infection in a previously asymptomatic CADASIL patient who presented with multiple infarcts and encephalopathy. cache = ./cache/cord-351440-vtf3o5ml.txt txt = ./txt/cord-351440-vtf3o5ml.txt === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === id = cord-339759-us1spoxu author = Cornelis, I. title = Clinical presentation, diagnostic findings and outcome in dogs diagnosed withpresumptive spinal‐only meningoen‐cephalomyelitis of unknown origin date = 2017-03-07 pages = extension = .txt mime = text/plain words = 4110 sentences = 205 flesch = 45 summary = The aims of this study were therefore to describe the signalment, clinical presentation, diagnostic findings, including results of MRI and long-term survival in dogs diagnosed with presumptive MUO of the spinal cord without concurrent clinical signs of intracranial involvement. Dogs were excluded if (1) the clinical records or imaging studies were incomplete or not available for review, (2) dogs showed clinical or neurological signs of intracranial involvement at time of presentation, (3) they had a peracute onset of clinical signs that were not progressive after 12 to 24 hours, (4) they had signs of extradural or extradural/intramedullary spinal cord compression on MRI and if (5) they had positive infectious disease titres or if clinical presentation, CSF analysis or necropsy findings were suggestive of SRMA or eosinophilic meningoencephalomyelitis (>10% eosinophils in CSF) (Dewey et al . cache = ./cache/cord-339759-us1spoxu.txt txt = ./txt/cord-339759-us1spoxu.txt === reduce.pl bib === id = cord-017031-i10q2569 author = Brix, Gunnar title = Basics of Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy date = 2008 pages = extension = .txt mime = text/plain words = 81282 sentences = 4018 flesch = 51 summary = The signal increase realized by low-flip angle excitation in combination with short repetition times is obtained, however, by omitting the 180° pulse generating a spinecho, as the 180° pulse not only inverts the phase of the transverse magnetization, but also the longitudinal magnetization (see Fig. 2 In contrast to the conventional imaging sequences, the nomenclature of the GRE sequences is not unified, but is handled differently by different manufacturers. If the flip angle is increased, the T1 contrast maximum will shift to a higher TR value dient of the FLASH sequence, refocusing gradient pulses are introduced in slice-selection direction as well as in the direction of frequency and phase encoding, through which the transverse magnetization is not destroyed after the data acquisition of the MR signal, but rather rephased or refocused (Fig. 2.4 .21). cache = ./cache/cord-017031-i10q2569.txt txt = ./txt/cord-017031-i10q2569.txt === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === id = cord-258556-hglp1vpm author = Peña-Solórzano, Carlos A. title = Findings from machine learning in clinical medical imaging applications – Lessons for translation to the forensic setting date = 2020-10-18 pages = extension = .txt mime = text/plain words = 8147 sentences = 383 flesch = 42 summary = Existing ML approaches in clinical imaging can likely be transferred to the forensic setting with careful consideration to account for the increased variability and temporal factors that affect the data used to train these algorithms. Van Tulder and de Bruijne [63] utilized convolutional RBMs, adding learning objectives that helped the algorithm to extract features for description and training data classification. J o u r n a l P r e -p r o o f Conclusions ML techniques have been applied to a large number of tasks that can be used in clinical medicine, where the algorithms most widely utilized in applications with medical images include RFs, SVMs, and CNNs. CNNs have shown better performance in the literature. cache = ./cache/cord-258556-hglp1vpm.txt txt = ./txt/cord-258556-hglp1vpm.txt === reduce.pl bib === === reduce.pl bib === id = cord-257075-9x0530cb author = Claudi, Carolin title = A Juxta-Articular Myxoma of the Thumb A Case Report date = 2020-04-20 pages = extension = .txt mime = text/plain words = 1312 sentences = 106 flesch = 63 summary = title: A Juxta-Articular Myxoma of the Thumb A Case Report Abstract Juxta-articular myxomata are benign tumors which are mostly encountered in the vicinity of larger joints. We present a case of a juxta-articular myxoma at the metacarpophalangeal joint of the thumb in a 40 year-old man. A follow-up MRI, scheduled without any clinical suspicion of tumor-recurrence, 9 months postoperatively, did not reveal any obvious recurrence. Juxta-articular myxomata (JAM) are benign soft tissue neoplasms of mesenchymal origin. This tumor of brown fat tissue shows spindle cells and 112 myxoid structures like a myxoma but would be positive for PS100 and CD 34 21 . Juxta-articular myxoma of the wrist: a 136 case report Juxta-articular myxoma: a clinical and pathologic study of 65 144 cases Juxta-articular myxoma of the shoulder 160 presenting as a cyst of the acromioclavicular joint: a case report cache = ./cache/cord-257075-9x0530cb.txt txt = ./txt/cord-257075-9x0530cb.txt === reduce.pl bib === id = cord-331268-kzy33hdb author = Lynch, Sharon G. title = Multiple sclerosis date = 1996-01-31 pages = extension = .txt mime = text/plain words = 13844 sentences = 885 flesch = 47 summary = Abnormalities in the cerebral hemispheres are frequently periventricular in distribution and only occasionally correlate with specific symptoms or signs.6,7 The accumulation of lesions in the frontal lobes is associated with a decline in memory.8 In addition, a change in the number of lesions on cranial MR images correlates with a change in overall clinical status as measured with standard scales.g Observations made with MRI are having a marked impact on both our basic knowledge of MS and on therapeutic trialsJo MRI studies will provide considerable insight into the natural history of the disease and will be an excellent independent variable in future clinical trials. Signs and symptoms that commonly occur as MS progresses include vertigo, tremor, incoordination, increasing spasticity, depression, mood swings, cognitive abnormalities, impotence or other sexual dysfunction, weakness, Lhermitte's sign, gait abnormalities, constipation, urinary incontinence, optic nerve pallor, fatigue, quadriparesis, dysarthria, loss of upper extremity coordination, and dysesthetic pain (Table 1) . cache = ./cache/cord-331268-kzy33hdb.txt txt = ./txt/cord-331268-kzy33hdb.txt === reduce.pl bib === === reduce.pl bib === id = cord-000977-ka4261wc author = nan title = ECR 2013 Book of Abstracts - B - Scientific Sessions date = 2013-03-07 pages = extension = .txt mime = text/plain words = 132895 sentences = 8080 flesch = 50 summary = Methods and Materials: Mean attenuation, contrast-to-noise ratio (CNR) and signal-to-noise ratio (SNR) at abdominal aorta, right renal artery (RRA) and left renal artery (LRA) were measured in 24 kidney donors who had undergone CTA with tube current modulation, 120 kVp, filtered back projection reconstruction algorithm (Group A) and were compared with 24 BMI-matched kidney donors who had undergone CTA with automated kVp selection and SAFIRE (Group B Purpose: Cerebral small vessel disease (SVD) is a common cause of cognitive impairment. Overall average score of SSF reconstructed segments was significantly higher compared with STD reconstruction ( Purpose: To evaluate the feasibility and imaging quality of double prospectively ECG-triggered high-pitch spiral acquisition mode for coronary computed tomography angiography (CTCA) in patients with atrial fibrillation (AF). cache = ./cache/cord-000977-ka4261wc.txt txt = ./txt/cord-000977-ka4261wc.txt === reduce.pl bib === id = cord-323581-qtasvgtd author = Zhang, Yu-Dong title = Advances in Multimodal Data Fusion in Neuroimaging: Overview, Challenges, and Novel Orientation date = 2020-07-17 pages = extension = .txt mime = text/plain words = 29003 sentences = 1517 flesch = 43 summary = We provide a review that encompasses (1) an overview of current challenges in multimodal fusion (2) the current medical applications of fusion for specific neurological diseases, (3) strengths and limitations of available imaging modalities, (4) fundamental fusion rules, (5) fusion quality assessment methods, and (6) the applications of fusion for atlas-based segmentation and quantification. Chapter 5 reviews the fundamental methods, which covers types, rules, atlas-based segmentation, decomposition, reconstruction, and quantification; Chapter 6 reviews subjective and objective assessment of data fusion in multimodal neuroimaging; Chapter 7 reviews the advantages of data fusion in improving the spatial/temporal resolution, distortion correction, and contrast; it also reviews the benefits of these advantages in fusing structural and functional images; Chapter 8 reviews atlas-based segmentations in multimodal imaging fusion; Chapter 9 reviews the quantification in multimodal neuroimaging fusion. cache = ./cache/cord-323581-qtasvgtd.txt txt = ./txt/cord-323581-qtasvgtd.txt === reduce.pl bib === === reduce.pl bib === id = cord-023353-2yoz1t6a author = nan title = ABSTRACTS FROM THE 2010 EVDI ANNUAL MEETING date = 2010-12-28 pages = extension = .txt mime = text/plain words = 30157 sentences = 1720 flesch = 48 summary = 3 Department of Physiology and Biometry, Ghent University, Belgium Introduction/Purpose: The microbubble-based contrast agents for ultrasonography have become more used in recent years in dogs1, and have been reported to be useful in differentiating adenomas from nonadenomatous lesions in human patients with adrenal masses2. Peak intensity Time to Introduction/Purpose: Studies with contrast enhanced ultrasonography (CEUS) on focal splenic lesions have shown discrepancies in accuracy for differentiating benign from malignant lesions.1-3 A speculative explanation for false positives may be the absence of a dual blood supply to the spleen compared to the liver. 1 The aim of the study was to test the hypothesis that the suggested maximum normal kidney size obtained from radiographs is too high and also to evaluate whether breed type (brachycephalic, doliocephalic, mesocephalic), age, gender, weight and body condition of the dog have an impact on kidney size. cache = ./cache/cord-023353-2yoz1t6a.txt txt = ./txt/cord-023353-2yoz1t6a.txt === reduce.pl bib === id = cord-014687-0am4l5ms author = nan title = SPR 2012 date = 2012-03-29 pages = extension = .txt mime = text/plain words = 98592 sentences = 5600 flesch = 43 summary = This presentation will focus on recent developments that have lead to a better understanding of the embryopathogenesis for fibropolycystic liver diseases (including choledochal cysts and Caroli disease), histopathological findings that have led to new classification systems for of pediatric vascular anomalies, technological advances and contrast agents in magnetic resonance imaging that are useful to characterize and limit the differential diagnosis of hepatic masses. Disclosure: Dr. Annapragada has indicated that he is a stock holder and consultant for Marval Biosciences Inc. Paper #: PA-067 Cardiovascular Image Quality Using a Nanoparticle CT Contrast Agent: Preliminary Studies in a Pig Model Rajesh Krishnamurthy, Radiology, Texas Children's Hospital, rxkrishn@texaschildrens.org; Ketan Ghaghada, Prakash Masand, Abhay Divekar, Eric Hoffman, Ananth Annapragada Purpose or Case Report: Image quality in a separate study using a long circulating, liposomal-based nanoscale blood pool iodinated contrast agent (NCTX) suggests clinical utility in pediatrics, potentially reducing difficulties in contrast-CT of children with congenital heart disease (CHD) including the size of intravenous cannula, need for accurate timing, inability to simultaneously opacify multiple targets of interest (requiring repeated contrast administration and/or repeated imaging). cache = ./cache/cord-014687-0am4l5ms.txt txt = ./txt/cord-014687-0am4l5ms.txt === reduce.pl bib === id = cord-328513-81yvcgul author = Bellastella, Giuseppe title = Revisitation of autoimmune hypophysitis: knowledge and uncertainties on pathophysiological and clinical aspects date = 2016-08-08 pages = extension = .txt mime = text/plain words = 9623 sentences = 462 flesch = 33 summary = • In patients with apparently idiopathic hypopituitarism especially if associated with other autoimmune diseases • In patients with hyperprolactinemia without pituitary adenoma at MRI, without hypothyroidism or associated to iatrogenic causes • In patients with hypoprolactinemia and post-partum lactation failure • In patients with empty sella • In patients with previous traumatic brain injury and in those with infectious meningitis • In patients treated with monoclonal antibodies for several types of tumor • In patients with IgG4-related syndrome • When APA are detected at high titre and with a particular immunofluorescence pattern in these patients, a pituitary MRI (if not yet performed) and a complete evaluation of pituitary function should be performed to discover those with pituitary impairment even at subclinical stage • In some cases, searching for antihypothalamus antibodies may help to ascertain the occurrence of an autoimmune process involving selectively the hypothalamic cells or associated with pituitary autoimmunity cache = ./cache/cord-328513-81yvcgul.txt txt = ./txt/cord-328513-81yvcgul.txt === reduce.pl bib === id = cord-345445-9t1vebey author = Radmanesh, Alireza title = COVID-19–associated Diffuse Leukoencephalopathy and Microhemorrhages date = 2020-05-21 pages = extension = .txt mime = text/plain words = 2227 sentences = 132 flesch = 34 summary = Diffuse leukoencephalopathy and juxtacortical and/or callosal microhemorrhages were brain imaging features in critically ill patients with coronavirus disease 2019. Herein, the authors report brain imaging features in 11 critically ill patients with COVID-19 with persistently diminished mental status who underwent MRI between April 5 and April 25, 2020. These imaging features include (a) confluent T2 hyperintensity and mild restricted diffusion in bilateral supratentorial deep and subcortical white matter (in 10 of 11 patients) and (b) multiple punctate microhemorrhages in juxtacortical and callosal white matter (in seven of 11 patients). In a series of 11 critically ill patients with COVID-19 who underwent brain MRI for a persistently depressed mental status, four patients had only diffuse leukoencephalopathy, one patient had only punctate microhemorrhages, and six patients had a combination of both. cache = ./cache/cord-345445-9t1vebey.txt txt = ./txt/cord-345445-9t1vebey.txt === reduce.pl bib === id = cord-015352-2d02eq3y author = nan title = ESPR 2017 date = 2017-04-26 pages = extension = .txt mime = text/plain words = 82253 sentences = 4479 flesch = 46 summary = Lapierre; Montreal/CA Summary: Objectives: To review the classification of visceroatrial situs To describe the associated cardiac and non-cardiac anomalies To illustrate typical findings in fetuses, neonates and children To discuss the surgical consideration and the long-term follow-up in these patients Abstract: By definition, the type of situs is determined by the relationship between the atria and the adjacent organs. As is often the case, radiology in JIA is all about: knowing your clinicians (i.e. the pretest likelihood for disease) being technically eloquent (e.g. using high-resolution US probes, not delaying post-contrast MRI acquisitions) knowing what is normal (e.g. normal undulations in the articular surface, focal bone marrow signal variation) not being dogmatic about individual observations or measurements interpreting your findings in a clinical context The lecture will demonstrate similarities and differences among joints and modalities in children with variable-severity JIA. cache = ./cache/cord-015352-2d02eq3y.txt txt = ./txt/cord-015352-2d02eq3y.txt === reduce.pl bib === id = cord-006849-vgjz74ts author = nan title = 27th International Congress of the European Association for Endoscopic Surgery (EAES) Sevilla, Spain, 12–15 June 2019 date = 2019-09-13 pages = extension = .txt mime = text/plain words = 222162 sentences = 14023 flesch = 48 summary = Methods: We are performing this procedures within a prospective randomized trial that is design to compare the long term results of LRYGB-B versus the standard laparoscopic Roux-en-Y gastric bypass.The video shows our technique in a case of a 46 years old female with a BMI of 46 Kg/m2. Material and methods: We present a video of the surgical intervention of a 32-year-old patient, with functional dyspepsia, with a casual diagnosis of a pseudocystic mass of the right colon after performing a CT scan: giant diverticulum of the hepatic colon angle with fecaloid content inside it under tension The patient goes to the emergency room for acute abdominal pain, pending colonoscopy, antibiotic treatment is established, and a laparoscopic approach is decided upon after the patient's evolution. Method: We present the case of a 65-year-old patient with surgical antecedent of laparoscopic low anterior resection due to rectal cancer, presenting in postoperative period an anastomosis leakage with severe peritonitis was identified and a laparotomy with end colostomy was performed. cache = ./cache/cord-006849-vgjz74ts.txt txt = ./txt/cord-006849-vgjz74ts.txt === reduce.pl bib === id = cord-021087-n4epxwn9 author = nan title = ECR – Final Programme: Scientific and Educational Exhibits date = 2004 pages = extension = .txt mime = text/plain words = 154170 sentences = 9372 flesch = 48 summary = Conclusions: MRI is useful to identify tumor response to Imatinib Mesylate in advanced GIST as from the early months of therapy with the following indicators of treatment activity: A) Size of lesions; B) signal intensity; C) vascularization; D) amount of degenerative tissue or necrosis; E) presence of peritoneal fluid. Materials and Methods: 34 patients (13 female, 21 male) from two centres with proven myocardial infarction by ECG, clinical and echo criteria underwent stress/ rest Tc99 sestamibi Gated SPECT scanning with a dual headed gamma camera and late contract enhanced MRI on identical 1.5 Tesla scanners in each centre using a protocol which imaged 15 minutes after injection of 0.1 mmol/kg IV gadolinium. These preliminary results illustrate the ability of MRI to assess the integrity of the TFCC and suggests its use as the first imaging method following plain radiography in the evaluation of patients with chronic posttraumatic pain on the ulnar side of the wrist. cache = ./cache/cord-021087-n4epxwn9.txt txt = ./txt/cord-021087-n4epxwn9.txt === reduce.pl bib === id = cord-006870-f5w6fw6q author = nan title = Abstracts Presented at the Neurocritical Care Society (NCS) 15th Annual Meeting date = 2017-09-19 pages = extension = .txt mime = text/plain words = 122221 sentences = 6828 flesch = 47 summary = Subjective perceptions of recovery were assessed via responses to the forced-choice dichotomized question, "Do you feel that you have made a complete recovery from the arrest?"Objective outcome measures of recovery included: Repeatable Battery for Neuropsychological Status (RBANS), Modified Lawton Physical Self-Maintenance Scale (L-ADL), Barthel Index (BI), Cerebral Performance Category Scale (CPC), Center for Epidemiological Studies-Depression scale (CES-D), and Post traumatic stress disorder-checklist (PTSD-C). Utilizing data from the Citicoline Brain Injury Treatment (COBRIT) trial, a prospective multicenter study, we identified 224 patients who met the inclusion criteria; 1) placement of an ICP monitoring device, 2) Glasgow coma score (GCS) less than 9, 3) EVD placement prior to arrival or within 6 hours of arrival at the study institution. The objective of this study was to examine the incidence rates of pre-specified medical and neurological ICU complications, and their impact on post-traumatic in-hospital mortality and 12month functional outcomes. cache = ./cache/cord-006870-f5w6fw6q.txt txt = ./txt/cord-006870-f5w6fw6q.txt === reduce.pl bib === id = cord-021206-4zyqqgs0 author = nan title = Scientific and Educational Exhibits date = 2007 pages = extension = .txt mime = text/plain words = 138669 sentences = 8591 flesch = 48 summary = Purpose: To analyze the clinical and imaging fi ndings of BI-RADS category 3 breast lesions by mammographic and ultrasonographic (US) assessment ultimately diagnosed as malignancy in retrospect Methods and Materials: Of 3,207 cases of US-guided core needle biopsy for 4 years, category 3 was given after biopsy, based on mammographic and sonographic evaluation, in 1,099 lesions (41.7%) that were composed of 462 palpable and 637 nonpalpable lesions. Background: Regional kinesis alteration of IVS is associated with different cardiac conditions which may have both pathological and physiological meanings of which the most important are the following: a) left bundle branch block that may determine intra-left ventricular asynchrony and may represent an independent predictor of severe cardiac events in heart failure patients; b) pulmonary embolism that increase right ventricle pressure; c) constrictive pericarditis; d) restrictive cardiomyopathies; e) post-operative cardiac surgery. cache = ./cache/cord-021206-4zyqqgs0.txt txt = ./txt/cord-021206-4zyqqgs0.txt === reduce.pl bib === id = cord-015359-gf32a6f1 author = nan title = B scientific sessions (SS) date = 2002 pages = extension = .txt mime = text/plain words = 159591 sentences = 9768 flesch = 51 summary = Methods and materials: 73 consecutive patients, clinically considered to have stage 1B tumour (confined to the cervix), underwent MR imaging studies at 1 T, according to the following protocol: fast spin-echo (FSE) T2-weighted, gadoliniumenhanced SE Tl-weighted, and fat-suppressed gadolinium-enhanced SE Tlweighted sequences. Purpose: To describe the radiological (thin section CT) findings correlated to activity and remission in ANCA associated pulmonary-renal small vessel vasculitis (SVV) Material and methods: We used retrospective analysis of 37 CTs, 27 in disease activity (8 first manifestations, 19 relapses) 10 im remission of 17 patients with pulmorenal syndrome (9 Wegener, 4 microscopic polyangiitis-MPA, 3 Churg-Strauss-syndrome, 1 idiopathic crescentic glomerulonephritis following the Chapel Hill classification) 7 women, 10 men, median 65.5 years (34 -84). Varghese, P.R. Mueller; Boston, MA/US Purpose: We sought to determine the incidence of malignancy and to assess a possible role for image guided biopsy of this category of renal masses Materials & methods: Of the 397 renal biopsies performed at our institution between 1991 and 2000; a total of 28 patients with 28 category III lesions, were identified for analysis. cache = ./cache/cord-015359-gf32a6f1.txt txt = ./txt/cord-015359-gf32a6f1.txt === reduce.pl bib === id = cord-023049-fio7cjj5 author = nan title = 2017 Peripheral Nerve Society Meeting July 8–12, 2017 Sitges, Barcelona, Spain date = 2017-06-22 pages = extension = .txt mime = text/plain words = 145485 sentences = 7436 flesch = 48 summary = Clinical efficacy (Medical Research Council sum score, 10-m walk, modified Inflammatory Neuropathy Cause and Treatment score, Overall Neuropathy Limitations Scale, Romberg test) and patient-reported outcomes (36-item Short Form Health Survey , Life Quality Index [LQI] ) were assessed at baseline and at regular intervals until the final visit (10-14 months after switching). To explore the issue of early biomarkers in FAP, we performed skin biopsy and compared IENF density with parameters of nerve conduction studies (NCS) and quantitative sensory testing (QST) on 36 subjects (23 men, aged 55.1 ± 11.1 years) with genetic confirmation of TTR-A97S: 17 patients and 19 carriers. Results: The Gly112Ser mutation causing CMT1C is a mild form of CMT, as patients walked on time, had less weakness than those with Charcot-Marie-Tooth Disease type 1A (CMT1A), had a Charcot Marie Tooth neuropathy score (CMTNS) indicative of mild disease, and had faster ulnar and median motor nerve conduction velocities compared to those with CMT1A. cache = ./cache/cord-023049-fio7cjj5.txt txt = ./txt/cord-023049-fio7cjj5.txt === reduce.pl bib === id = cord-009997-oecpqf1j author = nan title = 2018 ASPHO ABSTRACTS date = 2018-03-31 pages = extension = .txt mime = text/plain words = 182060 sentences = 10342 flesch = 48 summary = Completed cranial radiation and proceeded to allogeneic stem cell transplant with unrelated cord marrow donor and is disease free at approximately day +200.Case 2: 5 year-old female diagnosed with FLT3 and MLL negative AML and completed treatment per COG AAML1031 study on the low risk arm without Bortezomib. Design/Method: This study was a retrospective chart review that included patients 3 to 23 years old with sickle cell disease type SS and S 0 followed at St. Christopher's Hospital for Children. Background: Hydroxyurea, chronic blood transfusion, and bone marrow transplantation can reduce complications, and improve survival in sickle cell disease (SCD), but are associated with a significant decisional dilemma because of the inherent risk-benefit tradeoffs, and the lack of comparative studies. Brown University -Hasbro Children's Hospital, Providence, Rhode Island, United States Background: Despite clinical advances in the treatment of sickle cell disease (SCD) in pediatric and young adult patients, pain remains a significant source of disease-related morbidity. cache = ./cache/cord-009997-oecpqf1j.txt txt = ./txt/cord-009997-oecpqf1j.txt === reduce.pl bib === id = cord-015354-yknwveyz author = nan title = Abstracts_Poster presentations date = 2007-09-18 pages = extension = .txt mime = text/plain words = 221428 sentences = 13119 flesch = 54 summary = Material and Methods: Fourteen individuals (mean age 47±19y range 21-75y; 4W, 10M; including 10 volunteers and 4 patients with angiographically proved CAD) underwent dynamic PET imaging studies (21 frames) at rest and during adenosine stress (0.14mg/kg/min for 6 min) after injection of 1100MBq of 82Rb (Discovery LS, GEMS). Methods:Twenty-nine patients (21 males,8 females;62±11 yrs) with recent AMI were studied.Within 6 days after AMI, the patients were performed Tl-201 R-RD perfusion SPECT using 4 mCi activity.CMR was carried out 5-20 minutes after 0,15 mmol/kg of iv.Gadobutrol injection.Myocardial perfusion and contrast enhancement was analyzed using a 17 segment model.Myocardial perfusion was scored in Tl-201 SPECT as follows:0=normal (70%-100% maximal myocardial activity(mma), 1= 69-50% mma, 2= 49-30% mma ,3=29-10% mma and 4=<10% mma ;Myocardial contrast enhancement on CMR images was graded as:0=no contrast enhancement, 1=hyperenhancement of 0-25% of the wall thickness(WT) 2=hyperenhancement of 26-50 % of the WT, 3=hyperenhancement of 51-75 % of WT and 4=hyperenhancement of 76-100 % of WT.In CMR the existence of microvascular obstruction(MO) was also evaluated.Total segment scores(TSS) in R,RD and CMR for each patient were calculated by summing of 17 segment score values. cache = ./cache/cord-015354-yknwveyz.txt txt = ./txt/cord-015354-yknwveyz.txt ===== Reducing email addresses cord-000843-e1bn79ui cord-001221-due9tloa cord-302015-z2k6wuhm cord-000977-ka4261wc cord-014687-0am4l5ms cord-021206-4zyqqgs0 Creating transaction Updating adr table ===== Reducing keywords cord-003095-m9hmv8c8 cord-000843-e1bn79ui cord-006828-i88on326 cord-001221-due9tloa cord-006869-g2q1gpp0 cord-005105-twsy61oq cord-006876-v2m5l5wz cord-008085-3ihuqvei cord-011990-feqqx32n cord-006182-kck5e1ry cord-011669-hkkpw2bl cord-012651-7bllqwh1 cord-006880-9dgmdtj8 cord-011165-slu5531z cord-289605-gvc673ij cord-022659-chwk2bs4 cord-272623-j5gpww9q cord-267110-2g6owogs cord-302015-z2k6wuhm cord-306611-8s4scr7r cord-267605-efb10j3u cord-329750-purunxce cord-308270-343r91km cord-025535-dmcfy7ht cord-022594-fx044gcd cord-027730-xn12s005 cord-265293-l9omunq4 cord-323470-lpeeugdf cord-289861-i6bfuvq1 cord-325296-zrvykzof cord-288158-6gicgsj8 cord-302862-znnlyz3y cord-255240-ltatgq3e 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transaction Updating url table ===== Reducing named entities cord-003095-m9hmv8c8 cord-008085-3ihuqvei cord-011669-hkkpw2bl cord-011990-feqqx32n cord-289605-gvc673ij cord-012651-7bllqwh1 cord-001221-due9tloa cord-006876-v2m5l5wz cord-000843-e1bn79ui cord-306611-8s4scr7r cord-006869-g2q1gpp0 cord-006828-i88on326 cord-011165-slu5531z cord-267110-2g6owogs cord-302015-z2k6wuhm cord-272623-j5gpww9q cord-267605-efb10j3u cord-329750-purunxce cord-022659-chwk2bs4 cord-308270-343r91km cord-022594-fx044gcd cord-006182-kck5e1ry cord-005105-twsy61oq cord-006880-9dgmdtj8 cord-025535-dmcfy7ht cord-323470-lpeeugdf cord-255240-ltatgq3e cord-288158-6gicgsj8 cord-027730-xn12s005 cord-325296-zrvykzof cord-265293-l9omunq4 cord-302862-znnlyz3y cord-289861-i6bfuvq1 cord-009713-sxd4t2tz cord-330284-r3l6hdrk cord-102474-fmq98aa8 cord-346172-7ah22li0 cord-351440-vtf3o5ml cord-319930-ymqnb54a cord-308869-tuyac4oq cord-339759-us1spoxu cord-017031-i10q2569 cord-282342-5158g9kb cord-322890-w78tftva cord-258556-hglp1vpm cord-327543-kibjwfad cord-257075-9x0530cb cord-331268-kzy33hdb cord-338751-2eo7ityc cord-323581-qtasvgtd cord-328513-81yvcgul cord-346815-4t4gr0jz cord-023353-2yoz1t6a cord-345445-9t1vebey cord-015352-2d02eq3y cord-014687-0am4l5ms cord-000977-ka4261wc cord-006870-f5w6fw6q cord-021206-4zyqqgs0 cord-021087-n4epxwn9 cord-006849-vgjz74ts cord-015359-gf32a6f1 cord-023049-fio7cjj5 cord-009997-oecpqf1j cord-015354-yknwveyz Creating transaction Updating ent table ===== Reducing parts of speech cord-003095-m9hmv8c8 cord-012651-7bllqwh1 cord-011669-hkkpw2bl cord-272623-j5gpww9q cord-289605-gvc673ij cord-306611-8s4scr7r cord-008085-3ihuqvei cord-011990-feqqx32n cord-011165-slu5531z cord-267110-2g6owogs cord-302015-z2k6wuhm cord-267605-efb10j3u cord-308270-343r91km cord-025535-dmcfy7ht cord-323470-lpeeugdf cord-255240-ltatgq3e cord-288158-6gicgsj8 cord-329750-purunxce cord-325296-zrvykzof cord-289861-i6bfuvq1 cord-265293-l9omunq4 cord-302862-znnlyz3y cord-027730-xn12s005 cord-351440-vtf3o5ml cord-330284-r3l6hdrk cord-319930-ymqnb54a cord-346172-7ah22li0 cord-102474-fmq98aa8 cord-282342-5158g9kb cord-308869-tuyac4oq cord-327543-kibjwfad cord-339759-us1spoxu cord-257075-9x0530cb cord-338751-2eo7ityc cord-346815-4t4gr0jz cord-322890-w78tftva cord-345445-9t1vebey cord-258556-hglp1vpm cord-006828-i88on326 cord-022594-fx044gcd cord-328513-81yvcgul cord-331268-kzy33hdb cord-006869-g2q1gpp0 cord-323581-qtasvgtd cord-023353-2yoz1t6a cord-022659-chwk2bs4 cord-006876-v2m5l5wz cord-009713-sxd4t2tz cord-000843-e1bn79ui cord-006880-9dgmdtj8 cord-006182-kck5e1ry cord-017031-i10q2569 cord-015352-2d02eq3y cord-001221-due9tloa cord-014687-0am4l5ms cord-005105-twsy61oq cord-006870-f5w6fw6q cord-000977-ka4261wc cord-021206-4zyqqgs0 cord-023049-fio7cjj5 cord-015359-gf32a6f1 cord-021087-n4epxwn9 cord-009997-oecpqf1j cord-006849-vgjz74ts cord-015354-yknwveyz Creating transaction Updating pos table Building ./etc/reader.txt cord-009997-oecpqf1j cord-006870-f5w6fw6q cord-005105-twsy61oq cord-021206-4zyqqgs0 cord-000977-ka4261wc cord-021087-n4epxwn9 number of items: 65 sum of words: 2,631,373 average size in words: 59,803 average readability score: 47 nouns: patients; results; imaging; study; treatment; cases; disease; patient; time; diagnosis; data; years; group; age; brain; methods; lesions; images; findings; contrast; conclusion; analysis; studies; surgery; case; therapy; image; blood; months; use; children; risk; cancer; dose; days; evaluation; system; method; outcome; rate; care; tumor; tissue; complications; injury; technique; cell; groups; mm; volume verbs: used; performed; including; showing; compared; evaluate; associated; increased; following; presented; done; based; underwent; identified; assessed; found; reported; provides; developing; treated; demonstrated; determine; required; detect; obtain; improved; received; reduced; described; considered; measuring; allowing; suggests; related; observed; occurs; reviewed; revealed; seen; remains; made; needs; diagnosing; aiming; meant; enhanced; caused; decreasing; results; imaging adjectives: clinical; high; significant; non; normal; acute; different; surgical; mean; diagnostic; higher; low; first; common; early; cerebral; lower; renal; small; positive; laparoscopic; new; severe; primary; post; important; medical; patient; pediatric; multiple; specific; single; old; magnetic; pulmonary; functional; th; abdominal; right; initial; median; negative; cardiac; vascular; large; possible; standard; left; good; total adverbs: also; however; well; significantly; respectively; often; especially; therefore; even; prior; usually; clinically; still; retrospectively; previously; statistically; commonly; less; frequently; later; particularly; currently; recently; highly; approximately; nt; now; furthermore; prospectively; minimally; potentially; successfully; relatively; finally; alone; typically; widely; first; least; mainly; initially; subsequently; moreover; independently; aft; better; additionally; always; generally; almost pronouns: we; our; it; their; its; they; he; she; them; i; his; her; us; one; itself; you; him; mrs; your; themselves; my; me; iicas; igg4; ourselves; himself; cha; yourself; s; pbp; oneself; mg; imagej; theirs; ours; ncs-4; n20s; myself; in-111-octreotide; btfe; ≥25; ™; ωrf; Τo; ý; us/; upa; uhfus; u; tsd proper nouns: CT; MRI; MR; US; PET; Purpose; MS; ICH; T; Hospital; ICU; University; FDG; SAH; T2; M.; mg; A.; S.; ICP; C; IV; ±; TBI; CSF; EEG; C.; SPECT; Imaging; fi; CI; 3D; Group; J.; A; M; II; mm; CIDP; MRA; GBS; DWI; signifi; Medical; P.; MDCT; January; Children; G.; K. keywords: mri; patient; study; result; image; method; conclusion; imaging; csf; university; pet; hospital; high; eeg; disease; case; purpose; mdct; lesion; january; dwi; day; cns; child; treatment; tbi; sah; outcome; icu; icp; ich; group; gcs; finding; fdg; cta; covid-19; brain; year; spect; objective; nihss; medical; material; doppler; dog; diagnosis; dci; clinical; care one topic; one dimension: patients file(s): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031173/ titles(s): Accuracy of MRI diagnosis of early osteonecrosis of the femoral head: a meta-analysis and systematic review three topics; one dimension: patients; patients; patients file(s): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7149010/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100118/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7166380/ titles(s): ECR – Final Programme: Scientific and Educational Exhibits | 17th Annual Meeting, Neurocritical Care Society, October 15–18, 2019, Vancouver, Canada | 2017 Peripheral Nerve Society Meeting July 8–12, 2017 Sitges, Barcelona, Spain five topics; three dimensions: patients ct imaging; patients patient study; patients disease treatment; imaging mri mr; patients pet results file(s): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103164/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103238/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7166380/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7121495/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103105/ titles(s): B scientific sessions (SS) | Abstracts Presented at the Neurocritical Care Society (NCS) 15th Annual Meeting | 2017 Peripheral Nerve Society Meeting July 8–12, 2017 Sitges, Barcelona, Spain | Basics of Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy | Abstracts_Poster presentations Type: cord title: keyword-mri-cord date: 2021-05-25 time: 18:07 username: emorgan patron: Eric Morgan email: emorgan@nd.edu input: keywords:mri ==== make-pages.sh htm files ==== make-pages.sh complex files ==== make-pages.sh named enities ==== making bibliographics id: cord-338751-2eo7ityc author: Anzalone, Nicoletta title: Multifocal laminar cortical brain lesions: a consistent MRI finding in neuro-COVID-19 patients date: 2020-06-06 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: nan url: https://doi.org/10.1007/s00415-020-09966-2 doi: 10.1007/s00415-020-09966-2 id: cord-323470-lpeeugdf author: Ates, Omer Faruk title: Thorax magnetic resonance imaging findings in patients with coronavirus disease (COVID-19) date: 2020-08-15 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: RATIONALE AND OBJECTIVES: The aim of this study was to compare the findings found in thorax computed tomography (CT), which is increasingly used in the diagnosis of the important public health problem of coronavirus disease (COVID-19), and the findings of magnetic resonance imaging (MRI) as an important diagnostic alternative. MATERIALS AND METHODS: Thirty-two patients diagnosed with COVID-19 who underwent thorax CT for COVID pneumonia and MRI for any reason within 24 hours after CT were included in the study. The number of lobes affected, number of lobes containing ground-glass opacities and consolidation, number of nodules, distribution of lesions (central, peripheral or diffuse), lobes with centrilobular nodular pattern, and the presence of pleural effusion were recorded separately for both imaging methods. RESULTS: Seventeen of the patients were female (53%) and 15 were male (47%). The mean age of the patients was 60.5 (range, 20-85) years. A total of 31 patients (96%) had signs of pneumonia on CT. The most common finding in CT was ground-glass opacities in 29 patients (90.6%), followed by consolidation in 14 patients (43.75%). Both consolidation and ground-glass opacities were also observed in MRI in all of these patients. On CT, nodules were detected in 12 patients (37.5%) on CT and 11 patients (34.4%) on MRI. The sensitivity and specificity of MRI in nodule detection were calculated as 91.67% and 100%, respectively. CONCLUSION: Although thorax CT is widely used in the imaging of COVID-19 infection, due to its advantages, MRI can also be used as an alternative diagnostic tool. url: https://api.elsevier.com/content/article/pii/S1076633220304906 doi: 10.1016/j.acra.2020.08.009 id: cord-328513-81yvcgul author: Bellastella, Giuseppe title: Revisitation of autoimmune hypophysitis: knowledge and uncertainties on pathophysiological and clinical aspects date: 2016-08-08 words: 9623.0 sentences: 462.0 pages: flesch: 33.0 cache: ./cache/cord-328513-81yvcgul.txt txt: ./txt/cord-328513-81yvcgul.txt summary: • In patients with apparently idiopathic hypopituitarism especially if associated with other autoimmune diseases • In patients with hyperprolactinemia without pituitary adenoma at MRI, without hypothyroidism or associated to iatrogenic causes • In patients with hypoprolactinemia and post-partum lactation failure • In patients with empty sella • In patients with previous traumatic brain injury and in those with infectious meningitis • In patients treated with monoclonal antibodies for several types of tumor • In patients with IgG4-related syndrome • When APA are detected at high titre and with a particular immunofluorescence pattern in these patients, a pituitary MRI (if not yet performed) and a complete evaluation of pituitary function should be performed to discover those with pituitary impairment even at subclinical stage • In some cases, searching for antihypothalamus antibodies may help to ascertain the occurrence of an autoimmune process involving selectively the hypothalamic cells or associated with pituitary autoimmunity abstract: PURPOSE: This publication reviews the accepted knowledges and the findings still discussed on several features of autoimmune hypophysitis, including the most recently described forms, such as IgG4 and cancer immunotherapy- related hypophysitis. METHODS: The most characteristic findings and the pending controversies were derived from a literature review and previous personal experiences. A single paragraph focused on some atypical examples of the disease presenting under confounding pretences. RESULTS: Headache, visual field alterations and impaired pituitary secretion are the most frequent clinical findings of the disease. Pituitary biopsy, still considered the gold diagnostic standard, does not always receive consent from the patients. The role of magnetic resonance imaging is limited, as this disease may generate images similar to those of other diseases. The role of antipituitary and antihypothalamus antibodies is still discussed owing to methodological difficulties and also because the findings on the true pituitary antigen(s) are still debated. However, the low sensitivity and specificity of immunofluorescence, one of the more widely employed methods to detect these antibodies, may be improved, considering a predetermined cut-off titre and a particular kind of immunostaining. CONCLUSION: Autoimmune hypophysitis is a multifaceted disease, which may certainly be diagnosed by pituitary biopsy. However, the possible different clinical, laboratory and imaging features must be considered by the physician to avoid a misdiagnosis when examining a possibly affected patient. Therapeutic choice has to be made taking into account the clinical conditions and the degree of hypothalamic-pituitary involvement, but also considering that spontaneous remissions can occur. url: https://www.ncbi.nlm.nih.gov/pubmed/27503372/ doi: 10.1007/s11102-016-0736-z id: cord-302015-z2k6wuhm author: Bonardel, Claire title: Bilateral posterior infarction in a SARS-Cov-2 infected patient: discussion about an unusual case date: 2020-06-28 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: In time of SARS-Cov2 pandemic, neurologists need to be vigilant for cerebrovascular complications of Covid-19. We present a case of bilateral occipito-temporal infarction revealed by a sudden cortical blindness with haemorrhagic transformation after intravenous thrombolysis in a diabetic patient infected by Covid-19. Differential diagnoses are discussed in front of this unusual presentation and evolution. url: https://doi.org/10.1016/j.jstrokecerebrovasdis.2020.105095 doi: 10.1016/j.jstrokecerebrovasdis.2020.105095 id: cord-017031-i10q2569 author: Brix, Gunnar title: Basics of Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy date: 2008 words: 81282.0 sentences: 4018.0 pages: flesch: 51.0 cache: ./cache/cord-017031-i10q2569.txt txt: ./txt/cord-017031-i10q2569.txt summary: The signal increase realized by low-flip angle excitation in combination with short repetition times is obtained, however, by omitting the 180° pulse generating a spinecho, as the 180° pulse not only inverts the phase of the transverse magnetization, but also the longitudinal magnetization (see Fig. 2 In contrast to the conventional imaging sequences, the nomenclature of the GRE sequences is not unified, but is handled differently by different manufacturers. If the flip angle is increased, the T1 contrast maximum will shift to a higher TR value dient of the FLASH sequence, refocusing gradient pulses are introduced in slice-selection direction as well as in the direction of frequency and phase encoding, through which the transverse magnetization is not destroyed after the data acquisition of the MR signal, but rather rephased or refocused (Fig. 2.4 .21). abstract: In this chapter, the basic principles of magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) (Sects. 2.2, 2.3, and 2.4), the technical components of the MRI scanner (Sect. 2.5), and the basics of contrast agents and the application thereof (Sect. 2.6) are described. Furthermore, flow phenomena and MR angiography (Sect. 2.7) as well as diffusion and tensor imaging (Sect. 2.7) are elucidated. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7121495/ doi: 10.1007/978-3-540-29355-2_2 id: cord-011990-feqqx32n author: Carminati, Marco title: Challenges for Microelectronics in Non-Invasive Medical Diagnostics date: 2020-06-29 words: 9004.0 sentences: 394.0 pages: flesch: 45.0 cache: ./cache/cord-011990-feqqx32n.txt txt: ./txt/cord-011990-feqqx32n.txt summary: This paper reviews some recent results and technical challenges which still need to be addressed in terms of the design of CMOS analog application specific integrated circuits (ASICs) and their integration in the surrounding systems, in order to consolidate this technological paradigm. In multi-modal imaging, now that the compatibility of the acquisition chains (thousands of Silicon Photo-Multipliers channels) of gamma detectors with Tesla-level magnetic fields has been demonstrated, other development directions, enabled by microelectronics, can be envisioned in particular for single-photon emission tomography (SPECT): a faster and simplified operation, for instance, to allow transportable applications (bed-side) and hardware pre-processing that reduces the number of output signals and the image reconstruction time. Architecture of the gamma camera of the INSERT SPECT system: the current signals of 72 silicon photo-multiplier (SiPM) pixels are read by two ASICs [43] , featuring a low-impedance input stage, programmable shaper, peak stretcher and fast comparator to trigger the acquisition of events by the FPGA-based DAQ unit [44] . abstract: Microelectronics is emerging, sometimes with changing fortunes, as a key enabling technology in diagnostics. This paper reviews some recent results and technical challenges which still need to be addressed in terms of the design of CMOS analog application specific integrated circuits (ASICs) and their integration in the surrounding systems, in order to consolidate this technological paradigm. Open issues are discussed from two, apparently distant but complementary, points of view: micro-analytical devices, combining microfluidics with affinity bio-sensing, and gamma cameras for simultaneous multi-modal imaging, namely scintigraphy and magnetic resonance imaging (MRI). The role of integrated circuits is central in both application domains. In portable analytical platforms, ASICs offer miniaturization and tackle the noise/power dissipation trade-off. The integration of CMOS chips with microfluidics poses multiple open technological issues. In multi-modal imaging, now that the compatibility of the acquisition chains (thousands of Silicon Photo-Multipliers channels) of gamma detectors with Tesla-level magnetic fields has been demonstrated, other development directions, enabled by microelectronics, can be envisioned in particular for single-photon emission tomography (SPECT): a faster and simplified operation, for instance, to allow transportable applications (bed-side) and hardware pre-processing that reduces the number of output signals and the image reconstruction time. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374509/ doi: 10.3390/s20133636 id: cord-025535-dmcfy7ht author: Chelghoum, Rayene title: Transfer Learning Using Convolutional Neural Network Architectures for Brain Tumor Classification from MRI Images date: 2020-05-06 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: Brain tumor classification is very important in medical applications to develop an effective treatment. In this paper, we use brain contrast-enhanced magnetic resonance images (CE-MRI) benchmark dataset to classify three types of brain tumor (glioma, meningioma and pituitary). Due to the small number of training dataset, our classification systems evaluate deep transfer learning for feature extraction using nine deep pre-trained convolutional Neural Networks (CNNs) architectures. The objective of this study is to increase the classification accuracy, speed the training time and avoid the overfitting. In this work, we trained our architectures involved minimal pre-processing for three different epoch number in order to study its impact on classification performance and consuming time. In addition, the paper benefits acceptable results with small number of epoch in limited time. Our interpretations confirm that transfer learning provides reliable results in the case of small dataset. The proposed system outperforms the state-of-the-art methods and achieve 98.71% classification accuracy. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256397/ doi: 10.1007/978-3-030-49161-1_17 id: cord-257075-9x0530cb author: Claudi, Carolin title: A Juxta-Articular Myxoma of the Thumb A Case Report date: 2020-04-20 words: 1312.0 sentences: 106.0 pages: flesch: 63.0 cache: ./cache/cord-257075-9x0530cb.txt txt: ./txt/cord-257075-9x0530cb.txt summary: title: A Juxta-Articular Myxoma of the Thumb A Case Report Abstract Juxta-articular myxomata are benign tumors which are mostly encountered in the vicinity of larger joints. We present a case of a juxta-articular myxoma at the metacarpophalangeal joint of the thumb in a 40 year-old man. A follow-up MRI, scheduled without any clinical suspicion of tumor-recurrence, 9 months postoperatively, did not reveal any obvious recurrence. Juxta-articular myxomata (JAM) are benign soft tissue neoplasms of mesenchymal origin. This tumor of brown fat tissue shows spindle cells and 112 myxoid structures like a myxoma but would be positive for PS100 and CD 34 21 . Juxta-articular myxoma of the wrist: a 136 case report Juxta-articular myxoma: a clinical and pathologic study of 65 144 cases Juxta-articular myxoma of the shoulder 160 presenting as a cyst of the acromioclavicular joint: a case report abstract: Abstract Juxta-articular myxomata are benign tumors which are mostly encountered in the vicinity of larger joints. Few cases in the hand have been reported. We present a case of a juxta-articular myxoma at the metacarpophalangeal joint of the thumb in a 40 year-old man. The preoperative diagnostic work-up included 4D MR-Angiography and ultrasound. The histochemical examination of the resected tumor established the diagnosis definitively. A follow-up MRI, scheduled without any clinical suspicion of tumor-recurrence, 9 months postoperatively, did not reveal any obvious recurrence. At 14 months, the patient has full motion without pain and declined any further imaging. url: https://api.elsevier.com/content/article/pii/S2589514120300256 doi: 10.1016/j.jhsg.2020.04.002 id: cord-339759-us1spoxu author: Cornelis, I. title: Clinical presentation, diagnostic findings and outcome in dogs diagnosed withpresumptive spinal‐only meningoen‐cephalomyelitis of unknown origin date: 2017-03-07 words: 4110.0 sentences: 205.0 pages: flesch: 45.0 cache: ./cache/cord-339759-us1spoxu.txt txt: ./txt/cord-339759-us1spoxu.txt summary: The aims of this study were therefore to describe the signalment, clinical presentation, diagnostic findings, including results of MRI and long-term survival in dogs diagnosed with presumptive MUO of the spinal cord without concurrent clinical signs of intracranial involvement. Dogs were excluded if (1) the clinical records or imaging studies were incomplete or not available for review, (2) dogs showed clinical or neurological signs of intracranial involvement at time of presentation, (3) they had a peracute onset of clinical signs that were not progressive after 12 to 24 hours, (4) they had signs of extradural or extradural/intramedullary spinal cord compression on MRI and if (5) they had positive infectious disease titres or if clinical presentation, CSF analysis or necropsy findings were suggestive of SRMA or eosinophilic meningoencephalomyelitis (>10% eosinophils in CSF) (Dewey et al . abstract: OBJECTIVES: To summarise clinical presentation, diagnostic findings and long‐term outcome for dogs clinically diagnosed with meningoencephalomyelitis of unknown origin affecting the spinal cord alone. METHODS: Medical records were reviewed for dogs diagnosed with presumptive spinal‐only meningoencephalomyelitis of unknown origin between 2006 and 2015. RESULTS: 21 dogs were included; the majority presented with an acute (43%) or chronic (52%) onset of neurological signs. Ambulatory paresis was the most common neurological presentation (67%). Neurological examination most commonly revealed a T3‐L3 myelopathy, and spinal hyperaesthesia was a common finding (71%). A spinal cord lesion was visible in 90% of cases on magnetic resonance imaging. Eighteen lesions (86%) showed parenchymal contrast enhancement and 17 lesions (81%) showed contrast enhancement of overlying meninges. All dogs were treated with immunosuppressive doses of glucocorticosteroids, sometimes combined with cytosine arabinoside. At time of data capture, 10/21 dogs (48%) had died or been euthanased because of the condition. Overall median survival time was 669 days. CLINICAL SIGNIFICANCE: Meningoencephalomyelitis of unknown origin should be considered in the differential diagnosis of dogs presenting with a progressive myelopathy. Magnetic resonance imaging features can possibly help to distinguish presumptive meningoencephalomyelitis of unknown origin from other more common spinal diseases. Overall, long‐term survival is guarded, approximately 50% of dogs will die or be euthanased despite appropriate therapy. url: https://www.ncbi.nlm.nih.gov/pubmed/28267222/ doi: 10.1111/jsap.12622 id: cord-306611-8s4scr7r author: Fattore, Julia title: Revisiting the important role of magnetic resonance imaging (MRI) in long bone acute osteomyelitis: A case report of methicillin resistant Staphylococcus aureus acute tibial osteomyelitis with conventional radiography, computed tomography, and MRI date: 2020-08-22 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: The tibia is an atypical site of osteomyelitis (OM) in adults, and patients with this infection experience a significant degree of morbidity as well as the need for prolonged aggressive antibiotic therapy. The early diagnosis of OM remains challenging, and often relies on imaging modalities which are of variable sensitivity. We present a case of a 49-year-old male with a methicillin resistant Staphylococcus aureus (MRSa) left tibial OM, contiguous left knee septic arthritis, and concurrent bacteraemia. Eight days after the onset of pain in the left knee and lower limb, conventional radiography and computed tomography (CT) imaging had only subtleties of a soft tissue collection and a knee effusion. A MRI demonstrated significant involvement of his tibial bone with a collection, from which surgical specimens confirmed MRSa. This case demonstrates the difficulty of diagnosing early acute OM with conventional radiography and CT imaging, even after a week of symptoms in the affected limb. Given the poor sensitivity of conventional radiography and CT in the diagnosis of early acute OM, this case report illustrates how MRI is the imaging modality of choice in this setting. url: https://www.sciencedirect.com/science/article/pii/S1930043320303885 doi: 10.1016/j.radcr.2020.07.079 id: cord-330284-r3l6hdrk author: Gao, Min title: Machine Learning-Based Radiomics Predicting Tumor Grades and Expression of Multiple Pathologic Biomarkers in Gliomas date: 2020-09-11 words: 4941.0 sentences: 273.0 pages: flesch: 51.0 cache: ./cache/cord-330284-r3l6hdrk.txt txt: ./txt/cord-330284-r3l6hdrk.txt summary: The present study aimed to use conventional machine learning algorithms to predict the tumor grades and pathologic biomarkers on magnetic resonance imaging (MRI) data. The radiomic features were extracted from enhanced MRI images, and three frequently-used machine-learning models of LC, Support Vector Machine (SVM), and Random Forests (RF) were built for four predictive tasks: (1) glioma grades, (2) Ki67 expression level, (3) GFAP expression level, and (4) S100 expression level in gliomas. CONCLUSION: The machine-learning based radiomics approach can provide a non-invasive method for the prediction of glioma grades and expression levels of multiple pathologic biomarkers, preoperatively, with favorable predictive accuracy and stability. Three machine-learning-based models (LR, SVM, and RF) were built to perform the tasks: (1) classify the glioma grades, and (2) predict the expression levels of Ki67, S100, and GFAP. The machine-learning based radiomics approach was applied to predict glioma grades and the expression levels of pathologic biomarkers Ki67, GFAP, and S100 in low or high. abstract: BACKGROUND: The grading and pathologic biomarkers of glioma has important guiding significance for the individual treatment. In clinical, it is often necessary to obtain tumor samples through invasive operation for pathological diagnosis. The present study aimed to use conventional machine learning algorithms to predict the tumor grades and pathologic biomarkers on magnetic resonance imaging (MRI) data. METHODS: The present study retrospectively collected a dataset of 367 glioma patients, who had pathological reports and underwent MRI scans between October 2013 and March 2019. The radiomic features were extracted from enhanced MRI images, and three frequently-used machine-learning models of LC, Support Vector Machine (SVM), and Random Forests (RF) were built for four predictive tasks: (1) glioma grades, (2) Ki67 expression level, (3) GFAP expression level, and (4) S100 expression level in gliomas. Each sub dataset was split into training and testing sets at a ratio of 4:1. The training sets were used for training and tuning models. The testing sets were used for evaluating models. According to the area under curve (AUC) and accuracy, the best classifier was chosen for each task. RESULTS: The RF algorithm was found to be stable and consistently performed better than Logistic Regression and SVM for all the tasks. The RF classifier on glioma grades achieved a predictive performance (AUC: 0.79, accuracy: 0.81). The RF classifier also achieved a predictive performance on the Ki67 expression (AUC: 0.85, accuracy: 0.80). The AUC and accuracy score for the GFAP classifier were 0.72 and 0.81. The AUC and accuracy score for S100 expression levels are 0.60 and 0.91. CONCLUSION: The machine-learning based radiomics approach can provide a non-invasive method for the prediction of glioma grades and expression levels of multiple pathologic biomarkers, preoperatively, with favorable predictive accuracy and stability. url: https://doi.org/10.3389/fonc.2020.01676 doi: 10.3389/fonc.2020.01676 id: cord-102474-fmq98aa8 author: Gooding, K. M. title: Prognostic Imaging Biomarkers for Diabetic Kidney Disease (iBEAt): Study protocol date: 2020-01-16 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: Diabetic kidney disease (DKD) is traditionally classified based on albuminuria and reduced kidney function (estimated glomerular filtration rate (eGFR)), but these have limitations as prognostic biomarkers due to the heterogeneity of DKD. Novel prognostic markers are needed to improve stratification of patients based on risk of disease progression. The iBEAT study, part of the BEAt-DKD consortium, aims to determine whether renal imaging biomarkers (magnetic resonance imaging (MRI) and ultrasound (US)) provide insight into the pathogenesis and heterogeneity of DKD (primary aim), and whether they have potential as prognostic biomarkers in DKD progression (secondary aim). iBEAT is a prospective multi-centre observational cohort study recruiting 500 patients with type 2 diabetes (T2D) and eGFR > 30ml/min/1.73m2. At baseline each participant will undergo quantitative renal MRI and US imaging with central processing for MRI images. Blood sampling, urine collection and clinical examinations will be performed and medical history obtained at baseline, and these assessments will be repeated annually for 3 years. Biological samples will be stored in a central laboratory for later biomarker and validation studies. All data will be stored in a central data depository. Data analysis will explore the potential associations between imaging biomarkers and renal function, and whether the imaging biomarkers may improve the prediction of DKD progression rates. Embedded within iBEAT are ancillary substudies that will (1) validate imaging biomarkers against renal histopathology; (2) validate MRI based renal blood flow against water-labelled positron-emission tomography (PET); (3) develop machine-learning methods for automated processing of renal MRI images; (4) examine longitudinal changes in imaging biomarkers; (5) examine whether the glycocalyx, microvascular function and structure are associated with imaging biomarkers and eGFR decline; (6) a pilot study to examine whether the findings in T2D can be extrapolated to type 1 diabetes. The iBEAT study, the largest DKD imaging study to date, will provide invaluable insights into the progression and heterogeneity of DKD, and aims to contribute to a more personalized approach to the management of DKD in patients with type 2 diabetes. url: http://medrxiv.org/cgi/content/short/2020.01.13.20017228v1?rss=1 doi: 10.1101/2020.01.13.20017228 id: cord-027730-xn12s005 author: Jlassi, Amal title: Unsupervised Method Based on Superpixel Segmentation for Corpus Callosum Parcellation in MRI Scans date: 2020-05-31 words: 3940.0 sentences: 206.0 pages: flesch: 51.0 cache: ./cache/cord-027730-xn12s005.txt txt: ./txt/cord-027730-xn12s005.txt summary: title: Unsupervised Method Based on Superpixel Segmentation for Corpus Callosum Parcellation in MRI Scans Differently, Hofer proposed the only work based on tractography of DTI (Diffusion Tensor Imaging) by subdividing the CC into five regions from an average behavior observed via tractography in a specific population of 8 subjects [1] . On the second hand, differently to geometric parcellation methods, Rittner proposed a data-driven method based on the Watershed technique [15] . We propose a CC parcellation method based on SLIC, which is non-geometric and fully automatic superpixel segmentation technique. For the evaluation of the proposed parcellation method, we are the only study that used brain MRI scans from two public datasets. Since the Hofer and Witelson CC parcellation methods are based on geometric CC parcellation, their results did not vary among different subjects throughout the experimented dataset. abstract: In this paper, we introduce an unsupervised method for the parcellation of the Corpus Callosum (CC) from MRI images. Since there are no visible landmarks within the structure that explicit its parcels, non-geometric CC parcellation is a challenging task especially that almost of proposed methods are geometric or data-based. In fact, in order to subdivide the CC from brain sagittal MRI scans, we adopt the probabilistic neural network as a clustering technique. Then, we use a cluster validity measure based on the maximum entropy (Vmep) to obtain the optimal number of classes. After that, we obtain the isolated CC that we parcel automatically using SLIC (Simple Linear Iterative Clustering) as superpixel segmentation technique. The obtained results on two challenging public datasets prove the performance of the proposed method against geometric methods from the state of the art. Indeed, as best as we know, it is the first work that investigates the validation of a CC parcellation method on ground-truth datasets using many objective metrics. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313301/ doi: 10.1007/978-3-030-51517-1_10 id: cord-012651-7bllqwh1 author: Kalidindi, Kalyan Kumar Varma title: A rare cause of neurological deterioration to complete paraplegia after surgery for thoracic myelopathy: a case report date: 2019-06-05 words: 2049.0 sentences: 127.0 pages: flesch: 44.0 cache: ./cache/cord-012651-7bllqwh1.txt txt: ./txt/cord-012651-7bllqwh1.txt summary: title: A rare cause of neurological deterioration to complete paraplegia after surgery for thoracic myelopathy: a case report INTRODUCTION: Progressive deterioration of neurological status post-thoracic myelopathy surgery after a clinically stable period is rare and can pose a diagnostic dilemma. DISCUSSION: Ascending myelopathy is a potential but rare cause of delayed deterioration in neurological status after surgical intervention. SPAM has been described in the literature as an unusual cause of delayed neurological deterioration after traumatic spinal cord injury in cases where the deterioration could not be explained by mechanical instability, syrinx formation or therapeutic mis-intervention. This case report provides us with an insight into a potential cause akin to SPAM, which needs to be considered in a patient with progressive neurological deterioration after surgical decompression and stabilization for myelopathy. abstract: INTRODUCTION: Progressive deterioration of neurological status post-thoracic myelopathy surgery after a clinically stable period is rare and can pose a diagnostic dilemma. We present our experience with such a case where all known etiologies were ruled out and the cause of deterioration could not be conclusively identified. The course was found to be similar to sub-acute post-traumatic ascending myelopathy (SPAM). However, the condition has only been described for traumatic injuries so far. CASE PRESENTATION: Our patient presented a history of back pain and associated gait instability for one and a half months. There was no history of trauma. Investigations suggested an Anderson-like lesion at T11–T12 with cord edema at the same level suggestive of instability. She underwent posterior stabilization T9 to L2 and laminectomy of T11 as well as T12 under neuromonitoring. The postoperative sequence of events included an episode of pyrexia on the fifth day of surgery, neurological deterioration from the seventh day of surgery proceeding to complete paraplegia by the fourteenth day, no response to steroid treatment and no signs of recovery till two years post surgery. MRI findings were suggestive of SPAM, and there was no evidence of infection. DISCUSSION: Ascending myelopathy is a potential but rare cause of delayed deterioration in neurological status after surgical intervention. MRI findings of cord edema extending more than four levels above the involved segments is a characteristic finding of the condition. Ascending myelopathy may lead to complete cord injury. The precise cause of the condition is unknown and prognosis remains poor. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786435/ doi: 10.1038/s41394-019-0202-z id: cord-255240-ltatgq3e author: Kesserwani, Hassan title: Cerebral Microbleeds - To Treat or Not to Treat, That Is the Question: A Case Report With a Note on Its Radiologic Deconstruction and Therapeutic Nuances date: 2020-09-20 words: 3410.0 sentences: 193.0 pages: flesch: 52.0 cache: ./cache/cord-255240-ltatgq3e.txt txt: ./txt/cord-255240-ltatgq3e.txt summary: We present the case of an 86-year-old woman who has a vascular dementia, Binswanger''s syndrome, and coronary artery disease, who presented with more than five CMBs. We present this case in order to highlight the dilemma of anti-platelet therapy in this group of patients and we demonstrate the cardinal radiologic features of CMBs. We then segue into the pathologic correlates of CMBs and associated risk factors. If the magnetic resonance imaging (MRI) scanner software is endowed with a left-handed reference frame such as Siemens, the CMBs appear hyperintense on the phase map. Hence one faces a therapeutic dilemma; with such extensive cerebral white matter disease and stable coronary artery disease, is anti-platelet therapy warranted in the presence of more than five CMBs? [ In the study by Lau et al., in 1811 patients who were prescribed anti-platelet therapy, the five-year risk of recurrent ischemic stroke and hemorrhagic stroke both increased with the number of CMBs [6] . abstract: With the ubiquity of susceptibility weighted imaging (SWI), cerebral microbleeds (CMBs) are fast becoming a prevalent phenomenon. They are tightly associated with age, neurodegeneration and diverse vascular etiologies. CMBs have a unique radiological signature. Their morphology, number and topology are quite informative. They also pose a therapeutic conundrum, as they are associated with the risk of cerebral hemorrhage. We present the case of an 86-year-old woman who has a vascular dementia, Binswanger's syndrome, and coronary artery disease, who presented with more than five CMBs. We present this case in order to highlight the dilemma of anti-platelet therapy in this group of patients and we demonstrate the cardinal radiologic features of CMBs. We then segue into the pathologic correlates of CMBs and associated risk factors. We finally analyze the risk of anti-platelet therapy in the presence of CMBs, and we unfold the latest data on CMB number and anti-platelet therapy. url: https://www.ncbi.nlm.nih.gov/pubmed/33101796/ doi: 10.7759/cureus.10548 id: cord-308869-tuyac4oq author: Kido, Hidenori title: Kikuchi-Fujimoto disease (histiocytic necrotizing lymphadenitis) with atypical encephalitis and painful testitis: a case report date: 2017-02-01 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: BACKGROUND: Kikuchi-Fujimoto disease is a self-limited clinicopathologic entity that is increasingly recognized worldwide. Kikuchi-Fujimoto disease is characterized by cervical lymphadenopathy occurring in young adults. Neurologic involvement is rare, and testitis directly caused by Kikuchi-Fujimoto disease has not yet been reported. CASE PRESENTATION: A 19-year-old man was brought to our clinic with complaints of fever, headache, fatigue, and left lower quadrant pain that had persisted for 3 weeks. On physical examination, painful cervical lymphadenopathies were observed. Meningitis was suspected based on a cerebrospinal fluid examination, and left-sided orchitis was diagnosed based on findings from magnetic resonance imaging and ultrasonography. However, neither antibiotics nor antiviral drugs were effective in treating the patient’s symptoms. On the 20(th) day of hospitalization, the patient experienced a loss of consciousness, and brain T2-weighted magnetic resonance imaging showed asymmetrical, high-signal intensities in both basal nuclei and the left temporal lobe. Encephalitis was suspected, and the patient was treated with intravenous prednisolone pulse therapy (1 g/day) for 3 days and intravenous immunoglobulin therapy for 5 days. A left cervical lymph node biopsy showed apoptotic necrosis in paracortical and cortical areas with an abundance of macrophages and large lymphoid cells, which had irregular nuclei suggestive of Kikuchi-Fujimoto disease; the pathological findings from a brain biopsy were the same as those of the cervical lymph node biopsy. The encephalitis and cervical lymphadenopathies followed a benign course, as did the testitis. CONCLUSIONS: This is the first report of Kikuchi-Fujimoto disease involving painful testitis and pathologically proven asymmetrical brain regions. Kikuchi-Fujimoto disease should be included in the differential diagnosis when a patient presents with encephalitis, testitis, and fever of unknown origin. url: https://www.ncbi.nlm.nih.gov/pubmed/28143446/ doi: 10.1186/s12883-017-0807-4 id: cord-289605-gvc673ij author: Klaunberg, Brenda A. title: Considerations for Setting up a Small-Animal Imaging Facility date: 2004 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: Imaging techniques allow for the conduct of noninvasive, in vivo longitudinal small-animal studies, but also require access to expensive and complex equipment, and personnel who are properly trained in their use. The authors describe their planning and staffing of the NIH Mouse Imaging Facility, and highlight important issues to consider when designing a similar facility. url: https://www.ncbi.nlm.nih.gov/pubmed/15235626/ doi: 10.1038/laban0304-28 id: cord-319930-ymqnb54a author: Kremer, Stéphane title: Brain MRI Findings in Severe COVID-19: A Retrospective Observational Study date: 2020-06-16 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: BACKGROUND: Brain MRI parenchymal signal abnormalities have been in association with SARS-CoV-2. PURPOSE: Describe the neuroimaging findings (excluding ischemic infarcts) in patients with severe COVID-19 infection. METHODS: This was a retrospective study of patients evaluated from March 23th, 2020 to April 27th, 2020 at 16 hospitals. Inclusion criteria were: (i) positive nasopharyngeal or lower respiratory tract reverse transcriptase-polymerase chain reaction assays; (ii) severe COVID infection defined as requirement for hospitalization and oxygen therapy; (iii) neurologic manifestations; (iv) abnormal brain MRI. Exclusion criteria were patients with missing or non-contributory data regarding brain MRI or a brain MRI showing ischemic infarcts, cerebral venous thrombosis, or chronic lesions unrelated to the current event. Categorical data were compared using Fisher exact test. Quantitative data were compared using Student’s t-test or Wilcoxon test. A p-value lower than 0.05 was considered significant. RESULTS: Thirty men (81%) and 7 women (19%) met inclusion criteria, with a mean age of 61+/- 12 years (range: 8-78). The most common neurologic manifestations were alteration of consciousness (27/37, 73%), pathological wakefulness when the sedation was stopped (15/37, 41%), confusion (12/37, 32%), and agitation (7/37, 19%). The most frequent MRI findings were: signal abnormalities located in the medial temporal lobe in 16/37 (43%, 95% CI 27-59%) patients, non-confluent multifocal white matter hyperintense lesions on FLAIR and diffusion sequences, with variable enhancement, with associated hemorrhagic lesions in 11/37 patients (30%, 95% CI 15-45%), and extensive and isolated white matter microhemorrhages in 9/37 patients (24%, 95% CI 10-38%). A majority of patients (20/37, 54%) had intracerebral hemorrhagic lesions with a more severe clinical presentation: higher admission rate in intensive care units, 20/20 patients, 100% versus 12/17 patients, 71%, p=0.01; development of the acute respiratory distress syndrome in 20/20 patients, 100% versus 11/17 patients, 65%, p=0.005. Only one patient was positive for SARS-CoV-2 RNA in the cerebrospinal fluid. CONCLUSION: Patients with severe COVID-19 and without ischemic infarcts had a wide range of neurologic manifestations that were be associated with abnormal brain MRIs. Eight distinctive neuroradiological patterns were described. url: https://www.ncbi.nlm.nih.gov/pubmed/32544034/ doi: 10.1148/radiol.2020202222 id: cord-302862-znnlyz3y author: Lim, Peter A.C. title: Transverse Myelitis date: 2019-04-17 words: 4781.0 sentences: 254.0 pages: flesch: 38.0 cache: ./cache/cord-302862-znnlyz3y.txt txt: ./txt/cord-302862-znnlyz3y.txt summary: Following the acute management, which may include use of steroids, immunosuppressive drugs, and plasma exchange, a comprehensive medical rehabilitation program is important to optimize recovery from the resultant impairments and disabilities and manage associated complications. Factors associated with poor outcomes include severe initial symptoms with spinal shock, delayed presentation to the hospital after maximum deficits have already occurred, development of syringomyelia, and extensive MRI lesions. Patients with TM may present in the ambulatory clinic, urgent care center, or hospital setting with complaints of weakness of the limbs, sensory impairments, pain, and difficulties with the bowel and bladder. The functional limitations in a patient with TM usually depend on the level of spinal cord involvement and corresponding muscles affected. Effective management of intractable neuropathic pain using an intrathecal morphine pump in a patient with acute transverse myelitis abstract: Transverse myelitis (TM) is an inflammatory condition across the spinal cord, along one or more levels and in the absence of compression. Idiopathic acute TM is rare and with improvements in diagnostic tools and longer follow-up, the etiology which may include post-infectious, multiple sclerosis, or neuromyelitis optica often becomes clearer. The patient may present acutely with weakness, sensory impairments, or bowel and bladder changes. A careful history, physical examination, and appropriate diagnostic studies including blood tests and an MRI scan may help determine the diagnosis and etiology. Following the acute management, which may include use of steroids, immunosuppressive drugs, and plasma exchange, a comprehensive medical rehabilitation program is important to optimize recovery from the resultant impairments and disabilities and manage associated complications. Complications such as paralysis, autonomic dysfunction, neuropathic and musculoskeletal pain, spasticity, contractures, neurogenic bladder and bowels, skin breakdown, and psychological issues will benefit from the expertise of the physiatrist. Rehabilitation will include functional restoration with therapy as well as compensation of residual impairment with mobility and various other assistive devices. url: https://api.elsevier.com/content/article/pii/B9780323549479001620 doi: 10.1016/b978-0-323-54947-9.00162-0 id: cord-331268-kzy33hdb author: Lynch, Sharon G. title: Multiple sclerosis date: 1996-01-31 words: 13844.0 sentences: 885.0 pages: flesch: 47.0 cache: ./cache/cord-331268-kzy33hdb.txt txt: ./txt/cord-331268-kzy33hdb.txt summary: Abnormalities in the cerebral hemispheres are frequently periventricular in distribution and only occasionally correlate with specific symptoms or signs.6,7 The accumulation of lesions in the frontal lobes is associated with a decline in memory.8 In addition, a change in the number of lesions on cranial MR images correlates with a change in overall clinical status as measured with standard scales.g Observations made with MRI are having a marked impact on both our basic knowledge of MS and on therapeutic trialsJo MRI studies will provide considerable insight into the natural history of the disease and will be an excellent independent variable in future clinical trials. Signs and symptoms that commonly occur as MS progresses include vertigo, tremor, incoordination, increasing spasticity, depression, mood swings, cognitive abnormalities, impotence or other sexual dysfunction, weakness, Lhermitte''s sign, gait abnormalities, constipation, urinary incontinence, optic nerve pallor, fatigue, quadriparesis, dysarthria, loss of upper extremity coordination, and dysesthetic pain (Table 1) . abstract: Abstract Multiple sclerosis is a chronic disease that begins in late adolescence or adulthood. It is highly variable in its expression and severity. It is believed to be autoimmune in nature. The cause is unknown; both genetic and environmental factors have been implicated in the pathogenesis. MS generally presents with the acute or subacute onset of neurologic abnormalities that may wax and wane over many years. Diagnosis is generally made by means of observation of the clinical course in conjunction with a neurologic examination and laboratory tests. These tests may include magnetic resonance imaging of the head and spine, lumbar puncture, and evoked potentials. Treatment is based on general supportive care, the use of corticosteroids for relapses, and symptomatic management of ongoing problems. The frequency of relapses can be reduced with interferon-β (Betaseron). Copolymer 1 and interferon-β la are being evaluated by the U.S. Food and Drug Administration for approval for use for reduction in the frequency of relapses in relapsing-remitting MS. Treatment of chronic progression is often attempted with immunosuppressive agents such as corticosteroids, azathioprine, and cyclophosphamide. Use of other agents is being investigated. url: https://www.sciencedirect.com/science/article/pii/S0011502996900127 doi: 10.1016/s0011-5029(96)90012-7 id: cord-289861-i6bfuvq1 author: Macdonald-Laurs, Emma title: CSF neopterin, a useful biomarker in children presenting with influenza associated encephalopathy? date: 2018-09-28 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: PURPOSE: Neurological complications of influenza cause significant disease in children. Central nervous system inflammation, the presumed mechanism of influenza-associated encephalopathy, is difficult to detect. Characteristics of children presenting with severe neurological complications of influenza, and potential biomarkers of influenza-associated encephalopathy are described. METHODS: A multi-center, retrospective case-series of children with influenza and neurological complications during 2017 was performed. Enrolled cases met criteria for influenza-associated encephalopathy or had status epilepticus. Functional outcome at discharge was compared between groups using the Modified Rankin Scale (mRS). RESULTS: There were 22 children with influenza studied of whom 11/22 had encephalopathy and 11/22 had status epilepticus. Only one child had a documented influenza immunization. The biomarker CSF neopterin was tested in 10/11 children with encephalopathy and was elevated in 8/10. MRI was performed in all children with encephalopathy and was abnormal in 8 (73%). Treatment of children with encephalopathy was with corticosteroids or intravenous immunoglobulin in 9/11 (82%). In all cases oseltamivir use was low (59%) while admission to the intensive care unit was frequent (14/22, 66%). Clinical outcome at discharge was moderate to severe disability (mRS score > 2) in the majority of children with encephalopathy (7/11, 64%), including one child who died. Children with status epilepticus recovered to near-baseline function in all cases. CONCLUSION: Raised CSF neopterin was present in most cases of encephalopathy, and along with diffusion restriction on MRI, is a useful diagnostic biomarker. Lack of seasonal influenza vaccination represents a missed opportunity to prevent illness in children, including severe neurological disease. url: https://doi.org/10.1016/j.ejpn.2018.09.009 doi: 10.1016/j.ejpn.2018.09.009 id: cord-288158-6gicgsj8 author: Mahammedi, Abdelkader title: Imaging of Neurologic Disease in Hospitalized Patients with COVID-19: An Italian Multicenter Retrospective Observational Study date: 2020-05-21 words: 1099.0 sentences: 76.0 pages: flesch: 46.0 cache: ./cache/cord-288158-6gicgsj8.txt txt: ./txt/cord-288158-6gicgsj8.txt summary: title: Imaging of Neurologic Disease in Hospitalized Patients with COVID-19: An Italian Multicenter Retrospective Observational Study Of 725 consecutive hospitalized patients with coronavirus disease 2019, 108 (15%) had acute neurologic symptoms necessitating neurologic imaging. Imaging of Neurologic Disease in Hospitalized Patients with COVID-19: An Italian Multicenter Retrospective Observational Study E271 10 had acute ischemic infarcts and two had intracranial hemorrhage. The main neurologic imaging hallmark was acute ischemic infarcts, which were present in 34 of the 108 patients (31%) (30 [28%] on CT scans and four [20%] on MRI scans). Our study demonstrated that the neurologic imaging features of hospitalized patients with COVID-19 were variable, without a specific pattern but dominated by acute ischemic infarcts and intracranial hemorrhages. Currently, we have a poor mechanistic understanding of the neurologic symptoms in patients with COVID-19, whether these are arising from critical illness or from direct central nervous system invasion of severe acute respiratory syndrome coronavirus 2 (10). abstract: Of 725 consecutive hospitalized patients with coronavirus disease 2019, 108 (15%) had acute neurologic symptoms necessitating neurologic imaging. url: https://doi.org/10.1148/radiol.2020201933 doi: 10.1148/radiol.2020201933 id: cord-346815-4t4gr0jz author: Moshayedi, Pouria title: Triage of Acute Ischemic Stroke in Confirmed COVID-19: Large Vessel Occlusion Associated With Coronavirus Infection date: 2020-04-21 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: The outbreak of COVID-19 has posed a significant challenge to global healthcare. Acute stroke care requires rapid bedside attendance, imaging, and intervention. However, for acute stroke patients who have a diagnosis of or are under investigation for COVID-19, the concern for nosocomial transmission moderates operational procedures for acute stroke care. We present our experience with an in-hospital stroke code called on a COVID-19-positive patient with a left middle cerebral artery syndrome and the challenges faced for timely examination, imaging, and decision to intervene. The outlook for the ongoing COVID-19 pandemic necessitates the development of protocols to sustain timely and effective acute stroke care while mitigating healthcare-associated transmission. url: https://www.ncbi.nlm.nih.gov/pubmed/32373061/ doi: 10.3389/fneur.2020.00353 id: cord-327543-kibjwfad author: Ong, S. J. title: SIR HELMET (Safety In Radiology HEalthcare Localised Metrological EnviromenT): a low-cost negative-pressure isolation barrier for shielding MRI frontline workers from COVID-19 exposure date: 2020-07-01 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: • Low cost reusable acrylic and silicone rubber barrier shield design. • Localised negative pressure environment simulating isolation rooms. • Does not affect MRI image quality even on the most sensitive sequences. • Additional personal protective equipment for frontline healthcare professionals. url: https://www.ncbi.nlm.nih.gov/pubmed/32631627/ doi: 10.1016/j.crad.2020.06.015 id: cord-258556-hglp1vpm author: Peña-Solórzano, Carlos A. title: Findings from machine learning in clinical medical imaging applications – Lessons for translation to the forensic setting date: 2020-10-18 words: 8147.0 sentences: 383.0 pages: flesch: 42.0 cache: ./cache/cord-258556-hglp1vpm.txt txt: ./txt/cord-258556-hglp1vpm.txt summary: Existing ML approaches in clinical imaging can likely be transferred to the forensic setting with careful consideration to account for the increased variability and temporal factors that affect the data used to train these algorithms. Van Tulder and de Bruijne [63] utilized convolutional RBMs, adding learning objectives that helped the algorithm to extract features for description and training data classification. J o u r n a l P r e -p r o o f Conclusions ML techniques have been applied to a large number of tasks that can be used in clinical medicine, where the algorithms most widely utilized in applications with medical images include RFs, SVMs, and CNNs. CNNs have shown better performance in the literature. abstract: Machine learning (ML) techniques are increasingly being used in clinical medical imaging to automate distinct processing tasks. In post-mortem forensic radiology, the use of these algorithms presents significant challenges due to variability in organ position, structural changes from decomposition, inconsistent body placement in the scanner, and the presence of foreign bodies. Existing ML approaches in clinical imaging can likely be transferred to the forensic setting with careful consideration to account for the increased variability and temporal factors that affect the data used to train these algorithms. Additional steps are required to deal with these issues, by incorporating the possible variability into the training data through data augmentation, or by using atlases as a pre-processing step to account for death-related factors. A key application of ML would be then to highlight anatomical and gross pathological features of interest, or present information to help optimally determine the cause of death. In this review, we highlight results and limitations of applications in clinical medical imaging that use ML to determine key implications for their application in the forensic setting. url: https://doi.org/10.1016/j.forsciint.2020.110538 doi: 10.1016/j.forsciint.2020.110538 id: cord-022594-fx044gcd author: Pirko, Istvan title: Demyelinating Disorders of the Central Nervous System date: 2009-05-18 words: 25103.0 sentences: 1371.0 pages: flesch: 46.0 cache: ./cache/cord-022594-fx044gcd.txt txt: ./txt/cord-022594-fx044gcd.txt summary: If a patient presents with a history of two or more attacks, but objective clinical evidence only suggests one lesion, the following additional data is needed to confirm the diagnosis: the disease process has to be disseminated in space as demonstrated by MRI; alternatively, two or more MRI-detected lesions consistent with MS plus positive CSF would suffice to meet the newly defined criteria. The EBM calculations regarding this trial show an RRR of 24%, and ARR of 11%, and an NNT of 9 patients over 2 years in order to prevent one conversion to "clinically definite MS." These two studies provide support for considering early treatment in patients presenting with first attack, in the presence of multiple asymptomatic MRI lesions, but further studies are needed to determine whether this approach will provide a prolonged benefit on disease course. abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158368/ doi: 10.1016/b978-141603618-0.10048-7 id: cord-011165-slu5531z author: Rabbitt, Angela L. title: Characteristics associated with spine injury on magnetic resonance imaging in children evaluated for abusive head trauma date: 2020-01-04 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: BACKGROUND: Spine injuries are increasingly common in the evaluation for abusive head trauma (AHT), but additional information is needed to explore the utility of spine MRI in AHT evaluations and to ensure an accurate understanding of injury mechanism. OBJECTIVE: To assess the incidence of spine injury on MRI in children evaluated for AHT, and to correlate spine MRI findings with clinical characteristics. MATERIALS AND METHODS: We identified children younger than 5 years who were evaluated for AHT with spine MRI. Abuse likelihood was determined a priori by expert consensus. We blindly reviewed spine MRIs and compared spinal injury, abuse likelihood, patient demographics, severity of brain injury, presence of retinal hemorrhages, and pattern of head injury between children with and without spine injury. RESULTS: Forty-five of 76 (59.2%) children had spine injury. Spine injury was associated with more severe injury (longer intensive care stays [P<0.001], lower initial mental status [P=0.01] and longer ventilation times [P=0.001]). Overall abuse likelihood and spine injury were not associated. Spinal subdural hemorrhage was the only finding associated with a combination of retinal hemorrhages (P=0.01), noncontact head injuries (P=0.008) and a diagnosis of AHT (P<0.05). Spinal subdural hemorrhage was associated with other spine injury (P=0.004) but not with intracranial hemorrhage (P=0.28). CONCLUSION: Spinal injury is seen in most children evaluated for AHT and might be clinically and forensically valuable. Spinal subdural hemorrhage might support a mechanism of severe acceleration/deceleration head injury and a diagnosis of AHT. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7223732/ doi: 10.1007/s00247-019-04517-y id: cord-345445-9t1vebey author: Radmanesh, Alireza title: COVID-19–associated Diffuse Leukoencephalopathy and Microhemorrhages date: 2020-05-21 words: 2227.0 sentences: 132.0 pages: flesch: 34.0 cache: ./cache/cord-345445-9t1vebey.txt txt: ./txt/cord-345445-9t1vebey.txt summary: Diffuse leukoencephalopathy and juxtacortical and/or callosal microhemorrhages were brain imaging features in critically ill patients with coronavirus disease 2019. Herein, the authors report brain imaging features in 11 critically ill patients with COVID-19 with persistently diminished mental status who underwent MRI between April 5 and April 25, 2020. These imaging features include (a) confluent T2 hyperintensity and mild restricted diffusion in bilateral supratentorial deep and subcortical white matter (in 10 of 11 patients) and (b) multiple punctate microhemorrhages in juxtacortical and callosal white matter (in seven of 11 patients). In a series of 11 critically ill patients with COVID-19 who underwent brain MRI for a persistently depressed mental status, four patients had only diffuse leukoencephalopathy, one patient had only punctate microhemorrhages, and six patients had a combination of both. abstract: Diffuse leukoencephalopathy and juxtacortical and/or callosal microhemorrhages were brain imaging features in critically ill patients with coronavirus disease 2019. Coronavirus disease 2019 (COVID-19) has been reported in association with a variety of brain imaging findings such as ischemic infarct, hemorrhage, and acute hemorrhagic necrotizing encephalopathy. Herein, the authors report brain imaging features in 11 critically ill patients with COVID-19 with persistently diminished mental status who underwent MRI between April 5 and April 25, 2020. These imaging features include (a) confluent T2 hyperintensity and mild restricted diffusion in bilateral supratentorial deep and subcortical white matter (in 10 of 11 patients) and (b) multiple punctate microhemorrhages in juxtacortical and callosal white matter (in seven of 11 patients). The authors also discuss potential pathogeneses. © RSNA, 2020 Online supplemental material is available for this article. url: https://www.ncbi.nlm.nih.gov/pubmed/32437314/ doi: 10.1148/radiol.2020202040 id: cord-011669-hkkpw2bl author: Rodríguez-Sánchez, Diego Noé title: Lissencephaly in Shih Tzu dogs date: 2020-06-20 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: BACKGROUND: Lissencephaly is a brain malformation characterized by smooth and thickened cerebral surface, which may result in structural epilepsy. Lissencephaly is not common in veterinary medicine. Here, we characterize the first cases of lissencephaly in four Shih Tzu dogs, including clinical presentations and findings of magnetic resonance imaging of lissencephaly and several concomitant brain malformations. CASE PRESENTATION: Early-onset acute signs of forebrain abnormalities were observed in all dogs, which were mainly cluster seizures and behavioral alterations. Based on neurological examination, the findings were consistent with symmetrical and bilateral forebrain lesions. Metabolic disorders and inflammatory diseases were excluded. Magnetic resonance imaging for three dogs showed diffuse neocortical agyria and thickened gray matter while one dog had mixed agyria and pachygyria. Other features, such as internal hydrocephalus, supracollicular fluid accumulation, and corpus callosum hypoplasia, were detected concomitantly. Antiepileptic drugs effectively controlled cluster seizures, however, sporadic isolated seizures and signs of forebrain abnormalities, such as behavioral alterations, central blindness, and strabismus persisted. CONCLUSIONS: Lissencephaly should be considered an important differential diagnosis in Shih Tzu dogs presenting with early-onset signs of forebrain abnormalities, including cluster seizures and behavioral alterations. Magnetic resonance imaging was appropriate for ante-mortem diagnosis of lissencephaly and associated cerebral anomalies. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305484/ doi: 10.1186/s13028-020-00528-0 id: cord-308270-343r91km author: Sawlani, V. title: COVID-19-related intracranial imaging findings: a large single-centre experience date: 2020-09-15 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: Aim To describe the neuroradiological changes in patients with coronavirus disease 2019 (COVID-19). Materials and methods A retrospective review was undertaken of 3,403 patients who were confirmed positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, and admitted to our institution between 1 March 2020 and 31 May 2020, and who underwent neuroimaging. Abnormal brain imaging was evaluated in detail and various imaging patterns on magnetic resonance imaging MRI were identified. Results Of the 3,403 patients with COVID-19, 167 (4.9%) had neurological signs or symptoms warranting neuroimaging. The most common indications were delirium (44/167, 26%), focal neurology (37/167, 22%), and altered consciousness (34/167, 20%). Neuroimaging showed abnormalities in 23% of patients, with MRI being abnormal in 20 patients and computed tomography (CT) in 18 patients. The most consistent neuroradiological finding was microhaemorrhage with a predilection for the splenium of the corpus callosum (12/20, 60%) followed by acute or subacute infarct (5/20, 25%), watershed white matter hyperintensities (4/20, 20%), and susceptibility changes on susceptibility-weighted imaging (SWI) in the superficial veins (3/20, 15%), acute haemorrhagic necrotising encephalopathy (2/20, 10%), large parenchymal haemorrhage (2/20, 10%), subarachnoid haemorrhage (1/20, 5%), hypoxic–ischaemic changes (1/20, 5%), and acute disseminated encephalomyelitis (ADEM)-like changes (1/20, 5%). Conclusion Various imaging patterns on MRI were observed including acute haemorrhagic necrotising encephalopathy, white matter hyperintensities, hypoxic-ischaemic changes, ADEM-like changes, and stroke. Microhaemorrhages were the most common findings. Prolonged hypoxaemia, consumption coagulopathy, and endothelial disruption are the likely pathological drivers and reflect disease severity in this patient cohort. url: https://www.ncbi.nlm.nih.gov/pubmed/33023738/ doi: 10.1016/j.crad.2020.09.002 id: cord-265293-l9omunq4 author: Schönegger, Carmen Maria title: Smell and Taste Disorders in COVID-19 Patients: Objective Testing and Magnetic Resonance Imaging in Five Cases date: 2020-10-24 words: 2114.0 sentences: 124.0 pages: flesch: 51.0 cache: ./cache/cord-265293-l9omunq4.txt txt: ./txt/cord-265293-l9omunq4.txt summary: title: Smell and Taste Disorders in COVID-19 Patients: Objective Testing and Magnetic Resonance Imaging in Five Cases Those with objectifiable alteration in taste or smell were subjected to MRI with contrast agent to investigate possible involvement of the central nervous system. We encourage medical professionals to conduct specialized examinations and MRIs in the acute stage of disease, which guarantees an optimum patient care. The study was conducted on five patients reporting impairment of taste and smell with confirmed SARS-CoV-2 infection in East Tyrol. In case objective testing revealed alterations in taste or smell, patients were subjected to MRI in a timely manner. Three weeks after the first olfactory and gustatory examination, a follow-up testing was conducted with the three patients who also had a second MRI. The first MRI images showed slight alterations in one patient, which could be associated with a SARS-CoV-2 infection. Magnetic resonance imaging alteration of the brain in a patient with coronavirus disease 2019 (COVID-19) and anosmia abstract: Smell and taste disorders are acknowledged as characteristic symptoms for SARS-CoV-2 infection by now. These symptoms have been linked to a neuroinvasive course of disease. In this study, we investigated five consecutive COVID-19 patients with a prolonged course of dysosmia and dysgeusia. Those with objectifiable alteration in taste or smell were subjected to MRI with contrast agent to investigate possible involvement of the central nervous system. We found dysosmia and dysgeusia to be mostly objectifiable, but no evidence for neuroinvasiveness could be detected by MRI in the late stage of the disease. Alterations in taste and smell could be objectified in most patients. Nevertheless, no evidence for a neuroinvasive potential could be identified by MRI, at least in the late stage of disease. We encourage medical professionals to conduct specialized examinations and MRIs in the acute stage of disease, which guarantees an optimum patient care. url: https://www.ncbi.nlm.nih.gov/pubmed/33134844/ doi: 10.1007/s42399-020-00606-4 id: cord-267110-2g6owogs author: Sharma, Suvasini title: Acute Disseminated Encephalomyelitis date: 2017-11-17 words: 5206.0 sentences: 328.0 pages: flesch: 38.0 cache: ./cache/cord-267110-2g6owogs.txt txt: ./txt/cord-267110-2g6owogs.txt summary: In patients who have a relapse, biomarkers and imaging should help differentiate multiphasic ADEM, neuromyelitis optica spectrum disorder, anti-MOG antibody–associated relapsing demyelination, and multiple sclerosis. Acute disseminated encephalomyelitis (ADEM) is an acute immune-mediated inflammatory demyelinating condition involving the brain and spinal cord, which presents clinically with new-onset polyfocal neurologic features, which by definition include encephalopathy. A third ADEM-like event is not consistent with a diagnosis of multiphasic ADEM but indicates a chronic relapsing demyelinating disorder, such as relapsing optic neuritis, neuromyelitis optica spectrum disorder associated with antiaquaporin-4 antibodies, relapsing anti-MOG antibody-associated demyelination, or MS depending the clinical phenotype, biomarker, and neuroimaging findings. A long-term follow-up study using the 2007 International Pediatrics Multiple Sclerosis Study Group criteria evaluated the parameters at initial diagnosis and eventual conversion to MS in a cohort of 123 children with a first episode of acute CNS demyelination. Multiple sclerosis and acute disseminated encephalomyelitis diagnosed in children after long-term follow-up: comparison of presenting features An adult case of anti-myelin oligodendrocyte glycoprotein (MOG) antibody-associated multiphasic acute disseminated encephalomyelitis at 33-year intervals abstract: Acute disseminated encephalomyelitis (ADEM) is an inflammatory demyelinating syndrome with encephalopathy. ADEM typically affects young children, is often postinfectious, and is typically monophasic. MRI neuroimaging, which shows new lesions with poorly demarcated borders, but not old and established lesions, is essential to diagnosis. Autoantibodies against myelin oligodendrocyte glycoprotein (MOG) are found in ∼40% of ADEM patients, and these patients have different clinical and neuroimaging features to seronegative patients. Treatment in the acute phase is typically with high-dose corticosteroids and intravenous immunoglobulin or plasma exchange for refractory patients. Outcome is usually good, but residual cognitive, inattentive, and executive issues are likely underestimated. In patients who have a relapse, biomarkers and imaging should help differentiate multiphasic ADEM, neuromyelitis optica spectrum disorder, anti-MOG antibody–associated relapsing demyelination, and multiple sclerosis. url: https://www.sciencedirect.com/science/article/pii/B978032353088000018X doi: 10.1016/b978-0-323-53088-0.00018-x id: cord-272623-j5gpww9q author: Sun, Wei title: The pathogenesis of multifocal osteonecrosis date: 2016-07-11 words: 3117.0 sentences: 166.0 pages: flesch: 55.0 cache: ./cache/cord-272623-j5gpww9q.txt txt: ./txt/cord-272623-j5gpww9q.txt summary: For patients with osteonecrosis of both the hip and knee joints or for patients with a history of corticosteroid use or alcohol abuse who had osteonecrosis of one or more joints in the shoulder, ankle, wrist or elbow, magnetic resonance imaging (MRI) was also performed on other joints, regardless of whether these joints were symptomatic. Of the patients with a history of corticosteroid use, 18 had SLE, nine had chronic nephropathy, five had hematological diseases (four had acute lymphoblastic leukemia and one had non-Hodgkin''s lymphoma), five had an organ transplantation (four had a renal transplantation and one had a cardiac transplantation), three had Sjogren''s syndrome, two had dermatomyositis, two had multiple sclerosis and three received steroid therapy for trauma emergency. 3) Patients with corticosteroid use or alcohol abuse and who are diagnosed with osteonecrosis of one or more joints in the shoulder, ankle, wrist and elbow should have their hips and knees evaluated by MRI. abstract: Our objective was to study the incidence, etiology, and diagnosis of multifocal osteonecrosis (MFON) and its treatment options to facilitate an earlier diagnosis and to optimize treatment. A radiological investigation was performed in osteonecrosis patients with a high risk of MFON for a more accurate diagnosis between January 2010 and June 2015. For patients with osteonecrosis of both the hip and knee joints or for patients with a history of corticosteroid use or alcohol abuse who had osteonecrosis of one or more joints in the shoulder, ankle, wrist or elbow, magnetic resonance imaging (MRI) was also performed on other joints, regardless of whether these joints were symptomatic. Furthermore, we performed a radiological screening of 102 patients who had a negative diagnosis of MFON but were at a high risk; among them, another 31 MFON cases were successfully identified (30.4%). Thus, the incidence of MFON during the study period increased from 3.1% to 5.2%. Patients diagnosed with osteonecrosis and who are at a high risk of MFON should have their other joints radiologically examined when necessary. This will reduce missed diagnosis of MFON and facilitate an earlier diagnosis and treatment to achieve an optimal outcome. url: https://www.ncbi.nlm.nih.gov/pubmed/27404962/ doi: 10.1038/srep29576 id: cord-322890-w78tftva author: Suran, Jantra Ngosuwan title: IMAGING FINDINGS IN 14 DOMESTIC FERRETS (MUSTELA PUTORIUS FURO) WITH LYMPHOMA date: 2013-06-06 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: Lymphoma is the most common malignant neoplasia in domestic ferrets, Mustela putorius furo. However, imaging findings in ferrets with lymphoma have primarily been described in single case reports. The purpose of this retrospective study was to describe imaging findings in a group of ferrets with confirmed lymphoma. Medical records were searched between 2002 and 2012. A total of 14 ferrets were included. Radiographs (n = 12), ultrasound (n = 14), computed tomography (CT; n = 1), and magnetic resonance imaging (MRI; n = 1) images were available for review. Median age at the time of diagnosis was 5.2 years (range 3.25–7.6 years). Clinical signs were predominantly nonspecific (8/14). The time between the first imaging study and lymphoma diagnosis was 1 day or less in most ferrets (12). Imaging lesions were predominantly detected in the abdomen, and most frequently included intra‐abdominal lymphadenopathy (12/14), splenomegaly (8/14), and peritoneal effusion (11/14). Lymphadenopathy and mass lesions were typically hypoechoic on ultrasound. Mild peritoneal effusion was the only detected abnormality in two ferrets. Mild pleural effusion was the most common thoracic abnormality (3/12). Expansile lytic lesions were present in the vertebrae of two ferrets with T3‐L3 myelopathy and the femur in a ferret with lameness. Hyperattenuating, enhancing masses with secondary spinal cord compression were associated with vertebral lysis in CT images of one ferret. The MRI study in one ferret with myelopathy was inconclusive. Findings indicated that imaging characteristics of lymphoma in ferrets are similar to those previously reported in dogs, cats, and humans. url: https://doi.org/10.1111/vru.12068 doi: 10.1111/vru.12068 id: cord-282342-5158g9kb author: Takao, Masaki title: Transitional changes in the incidence of hip osteonecrosis among renal transplant recipients date: 2019-07-04 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: Abstract Background Immunosuppressive therapy for renal allograft recipients has changed substantially since the introduction of the anti-CD25 monoclonal antibody, basiliximab. We hypothesized that recent improvements in immunosuppressive treatment may reduce the incidence of osteonecrosis of the femoral head (ONFH). This study aimed to investigate transitional changes in the incidence of OFNH among renal transplant recipients by MRI. Methods Participants comprised 110 patients who had undergone renal transplantation from 2003 to 2012, during which time basiliximab was in regular use at our institute (Recent group), and 232 patients who had undergone RT between 1986 and 2003 (Past group). We compared ONFH incidence between the two groups and evaluated risk factors for ONFH, including immunosuppressants (calcineurin inhibitors, basiliximab, and/or steroids) and postoperative renal function. Results Incidence of ONFH was lower in the Recent group (0%) than in the Past group (3.4%; p = 0.043). In the Recent group, age was greater, ABO/human leukocyte antigen incompatibility was worse, while steroid dose was decreased and post-transplant renal function was improved. Cumulative methylprednisolone dose at postoperative week 2 and delayed graft function were identified as risk factors for ONFH. Conclusion Risk of ONFH after renal transplantation has fallen with the advent of regular use of basiliximab, although this agent does not appear to be a factor directly associated with the incidence of ONFH. Study design Clinical prognostic study (Level III case control study). url: https://api.elsevier.com/content/article/pii/S0949265819301927 doi: 10.1016/j.jos.2019.06.009 id: cord-008085-3ihuqvei author: Thomas, William B. title: Nonneoplastic disorders of the brain date: 2005-07-06 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: Computed tomography (CT) and magnetic resonance imaging (MRI) are helpful in the diagnosis of many nonneoplastic brain disorders in the dog and cat. The ability of CT and MRI to depict normal and abnormal anatomy facilitates the identification of developmental anomalies, including hydrocephalus, Chiari malformations, arachnoid cysts, and cerebellar hypoplasia. These imaging modalities also allow the detection of hemorrhage and infarction and are therefore useful in the evaluation of spontaneous cerebrovascular disorders and head trauma. Finally, many inflammatory diseases, such as encephalitis, brain abscess, and parasite migration, cause abnormalities detectable by CT and MRI. Although more research on the imaging features of specific nonneoplastic brain disorders is needed, current information indicates that CT and MRI are useful in the management of these disorders. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7128835/ doi: 10.1016/s1096-2867(99)80030-9 id: cord-329750-purunxce author: Waldman, Amy title: Childhood multiple sclerosis: A review date: 2006-06-28 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: Multiple sclerosis (MS) is an autoimmune demyelinating disorder of the central nervous system (CNS) that is increasingly recognized as a disease that affects children. Similar to adult‐onset MS, children present with visual and sensory complaints, as well as weakness, spasticity, and ataxia. A lumbar puncture can be helpful in diagnosing MS when CSF immunoglobulins and oligoclonal bands are present. White matter demyelinating lesions on MRI are required for the diagnosis; however, children typically have fewer lesions than adults. Many criteria have been proposed to diagnose MS that have been applied to children, mostly above 10 years of age. The recent revisions to the McDonald criteria allow for earlier diagnosis, such as after a clinically isolated event. However, children are more likely than adults to have monosymptomatic illnesses. None of the approved disease‐modifying therapies used in adult‐onset MS have been approved for pediatrics; however, a few studies have verified their safety and tolerability in children. Although children and adults with MS have similar neurological symptoms, laboratory (cerebrospinal fluid) data, and neuroimaging findings, the clinical course, pathogenesis, and treatment of childhood onset MS require further investigation. MRDD Research Reviews 2006;12:147–156. © 2006 Wiley‐Liss, Inc. url: https://www.ncbi.nlm.nih.gov/pubmed/16807911/ doi: 10.1002/mrdd.20105 id: cord-346172-7ah22li0 author: Yang, Shuyi title: Clinical Potential of UTE‐MRI for Assessing COVID‐19: Patient‐ and Lesion‐Based Comparative Analysis date: 2020-06-03 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: BACKGROUND: Chest computed tomography (CT) has shown tremendous clinical potential for screening, diagnosis, and surveillance of COVID‐19. However, safety concerns are warranted due to repeated exposure of X‐rays over a short period of time. Recent advances in MRI suggested that ultrashort echo time MRI (UTE‐MRI) was valuable for pulmonary applications. PURPOSE: To evaluate the effectiveness of UTE‐MRI for assessing COVID‐19. STUDY TYPE: Prospective. POPULATION: In all, 23 patients with COVID‐19 and with an average interval of 2.81 days between hospital admission and image examination. FIELD STRENGTH/SEQUENCE: 3T; Respiratory‐gated three‐dimensional radial UTE pulse sequence. ASSESSMENT: Image quality score. Patient‐ and lesion‐based interobserver and intermethod agreement for identifying the representative image findings of COVID‐19. STATISTICAL TESTS: Wilcoxon‐rank sum test, Kendall's coefficient of concordance (Kendall's W), intraclass coefficients (ICCs), and weighted kappa statistics. RESULTS: There was no significant difference between the image quality of CT and UTE‐MRI (CT vs. UTE‐MRI: 4.3 ± 0.4 vs. 4.0 ± 0.5, P = 0.09). Moreover, both patient‐ and lesion‐based interobserver agreement of CT and UTE‐MRI for evaluating the image signs of COVID‐19 were determined as excellent (ICC: 0.939–1.000, P < 0.05; Kendall's W: 0.894–1.000, P < 0.05.). In addition, the intermethod agreement of two image modalities for assessing the representative findings of COVID‐19 including affected lobes, total severity score, ground glass opacities (GGO), consolidation, GGO with consolidation, the number of crazy paving pattern, and linear opacities, as well as pseudocavity were all determined as substantial or excellent (kappa: 0.649–1.000, P < 0.05; ICC: 0.913–1.000, P < 0.05). DATA CONCLUSION: Pulmonary MRI with UTE is valuable for assessing the representative image findings of COVID‐19 with a high concordance to CT. EVIDENCE LEVEL: 2 TECHNICAL EFFICACY STAGE: 3 url: https://doi.org/10.1002/jmri.27208 doi: 10.1002/jmri.27208 id: cord-351440-vtf3o5ml author: Zhang, Tianshu title: COVID-19-Associated Acute Multi-infarct Encephalopathy in an Asymptomatic CADASIL Patient date: 2020-10-06 words: 1599.0 sentences: 92.0 pages: flesch: 47.0 cache: ./cache/cord-351440-vtf3o5ml.txt txt: ./txt/cord-351440-vtf3o5ml.txt summary: The chronological changes from the initial DWI and ADC images to the disappearance of these signals in the follow-up MRI support that the patient had acute subcortical ischemic changes or necrotic changes. The brain MRI showed multiple DWI lesions and corresponding ADC sequence changes which were consistent with multiple acute infarcts possibly related to hypoxic-ischemic injury from systemic perturbations and resultant tissue hypoxia. The distribution of the CT and MRI changes in our case is similar to a recent case report of acute hemorrhagic necrotizing encephalopathy in a COVID-19 patient [3] , which case, to our knowledge, was not tested for a pathological NOTCH3 mutation. The clinical features and CT and MRI changes are consistent with acute subcortical multiple infarctions which could be related to or provoked by a viral infection. Our described case is an atypical presentation of an acute COVID-19 infection in a previously asymptomatic CADASIL patient who presented with multiple infarcts and encephalopathy. abstract: nan url: https://doi.org/10.1007/s12028-020-01119-7 doi: 10.1007/s12028-020-01119-7 id: cord-003095-m9hmv8c8 author: Zhang, Ya-Zhou title: Accuracy of MRI diagnosis of early osteonecrosis of the femoral head: a meta-analysis and systematic review date: 2018-07-04 words: 2734.0 sentences: 159.0 pages: flesch: 55.0 cache: ./cache/cord-003095-m9hmv8c8.txt txt: ./txt/cord-003095-m9hmv8c8.txt summary: Heterogeneity of the included studies were reviewed to select proper effect model for pooled weighted sensitivity, specificity, and diagnostic odds ratio (DOR). RESULTS: Forty-three studies related to diagnostic accuracy of MRI to detect early osteonecrosis of the femoral head were involved in the meta-analysis. Therefore, in this paper, a systematic review and meta-analysis of all qualified studies were performed to explore the diagnosis accuracy of MRI in early ANFH. The studies that met the following criteria were included in our review: (1) prospective cohort study or cross-sectional study; (2) the research objects are patients suspected with early osteonecrosis of the femoral head without other serious diseases; (3) the studies provided the data of true positive (TP), false positive (FP), false negative (FN), and true negative (TN); and (4) the publications were only available in English and Chinese. Comparative analysis of diagnostic value of X -ray, CT and MRI in early diagnosis of avascular necrosis of femoral head abstract: OBJECTIVE: To evaluate the overall diagnostic value related to magnetic resonance imaging (MRI) in patients with early osteonecrosis of the femoral head. METHODS: By searching multiple databases and sources, including PubMed, Cochrane, and Embase database, by the index words updated in December 2017, qualified studies were identified and relevant literature sources were also searched. The qualified studies included prospective cohort studies and cross-sectional studies. Heterogeneity of the included studies were reviewed to select proper effect model for pooled weighted sensitivity, specificity, and diagnostic odds ratio (DOR). Summary receiver operating characteristic (SROC) analyses were performed for meniscal tears. RESULTS: Forty-three studies related to diagnostic accuracy of MRI to detect early osteonecrosis of the femoral head were involved in the meta-analysis. The global sensitivity and specificity of MRI in early osteonecrosis of the femoral head were 93.0% (95% CI 92.0–94.0%) and 91.0% (95% CI 89.0%–93.0%), respectively. The global positive likelihood ratio and global negative likelihood ratio of MRI in early osteonecrosis of the femoral head were 2.74 (95% CI 1.98–3.79) and 0.18 (95% CI 0.14–0.23), respectively. The global DOR was 27.27 (95% CI 17.02–43.67), and the area under the SROC was 93.38% (95% CI 90.87%–95.89%). CONCLUSIONS: This review provides a systematic review and meta-analysis to evaluate the diagnostic accuracy of MRI in early osteonecrosis of the femoral head. Moderate to strong evidence indicated that MRI appears to be significantly associated with higher diagnostic accuracy for early osteonecrosis of the femoral head. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031173/ doi: 10.1186/s13018-018-0836-8 id: cord-323581-qtasvgtd author: Zhang, Yu-Dong title: Advances in Multimodal Data Fusion in Neuroimaging: Overview, Challenges, and Novel Orientation date: 2020-07-17 words: 29003.0 sentences: 1517.0 pages: flesch: 43.0 cache: ./cache/cord-323581-qtasvgtd.txt txt: ./txt/cord-323581-qtasvgtd.txt summary: We provide a review that encompasses (1) an overview of current challenges in multimodal fusion (2) the current medical applications of fusion for specific neurological diseases, (3) strengths and limitations of available imaging modalities, (4) fundamental fusion rules, (5) fusion quality assessment methods, and (6) the applications of fusion for atlas-based segmentation and quantification. Chapter 5 reviews the fundamental methods, which covers types, rules, atlas-based segmentation, decomposition, reconstruction, and quantification; Chapter 6 reviews subjective and objective assessment of data fusion in multimodal neuroimaging; Chapter 7 reviews the advantages of data fusion in improving the spatial/temporal resolution, distortion correction, and contrast; it also reviews the benefits of these advantages in fusing structural and functional images; Chapter 8 reviews atlas-based segmentations in multimodal imaging fusion; Chapter 9 reviews the quantification in multimodal neuroimaging fusion. abstract: Multimodal fusion in neuroimaging combines data from multiple imaging modalities to overcome the fundamental limitations of individual modalities. Neuroimaging fusion can achieve higher temporal and spatial resolution, enhance contrast, correct imaging distortions, and bridge physiological and cognitive information. In this study, we analyzed over 450 references from PubMed, Google Scholar, IEEE, ScienceDirect, Web of Science, and various sources published from 1978 to 2020. We provide a review that encompasses (1) an overview of current challenges in multimodal fusion (2) the current medical applications of fusion for specific neurological diseases, (3) strengths and limitations of available imaging modalities, (4) fundamental fusion rules, (5) fusion quality assessment methods, and (6) the applications of fusion for atlas-based segmentation and quantification. Overall, multimodal fusion shows significant benefits in clinical diagnosis and neuroscience research. Widespread education and further research amongst engineers, researchers and clinicians will benefit the field of multimodal neuroimaging. url: https://api.elsevier.com/content/article/pii/S1566253520303183 doi: 10.1016/j.inffus.2020.07.006 id: cord-267605-efb10j3u author: Zheng, Li-Zhen title: Steroid-Associated Hip Joint Collapse in Bipedal Emus date: 2013-10-21 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: In this study we established a bipedal animal model of steroid-associated hip joint collapse in emus for testing potential treatment protocols to be developed for prevention of steroid-associated joint collapse in preclinical settings. Five adult male emus were treated with a steroid-associated osteonecrosis (SAON) induction protocol using combination of pulsed lipopolysaccharide (LPS) and methylprednisolone (MPS). Additional three emus were used as normal control. Post-induction, emu gait was observed, magnetic resonance imaging (MRI) was performed, and blood was collected for routine examination, including testing blood coagulation and lipid metabolism. Emus were sacrificed at week 24 post-induction, bilateral femora were collected for micro-computed tomography (micro-CT) and histological analysis. Asymmetric limping gait and abnormal MRI signals were found in steroid-treated emus. SAON was found in all emus with a joint collapse incidence of 70%. The percentage of neutrophils (Neut %) and parameters on lipid metabolism significantly increased after induction. Micro-CT revealed structure deterioration of subchondral trabecular bone. Histomorphometry showed larger fat cell fraction and size, thinning of subchondral plate and cartilage layer, smaller osteoblast perimeter percentage and less blood vessels distributed at collapsed region in SAON group as compared with the normal controls. Scanning electron microscope (SEM) showed poor mineral matrix and more osteo-lacunae outline in the collapsed region in SAON group. The combination of pulsed LPS and MPS developed in the current study was safe and effective to induce SAON and deterioration of subchondral bone in bipedal emus with subsequent femoral head collapse, a typical clinical feature observed in patients under pulsed steroid treatment. In conclusion, bipedal emus could be used as an effective preclinical experimental model to evaluate potential treatment protocols to be developed for prevention of ON-induced hip joint collapse in patients. url: https://doi.org/10.1371/journal.pone.0076797 doi: 10.1371/journal.pone.0076797 id: cord-325296-zrvykzof author: Zuhorn, Frédéric title: Parainfectious encephalitis in COVID-19: “The Claustrum Sign” date: 2020-09-03 words: 892.0 sentences: 58.0 pages: flesch: 33.0 cache: ./cache/cord-325296-zrvykzof.txt txt: ./txt/cord-325296-zrvykzof.txt summary: Follow-up has been carried out four months later showing a normalization in cell count of CSF and improvement of MRI findings, although the claustrum lesions persisted. While immunological markers remained unspecific and imaging findings of acute necrotizing encephalitis were absent in our patient, brain MRI disclosed a unique pattern, a.k.a. the claustrum sign. Common MRI findings in a recent study of COVID-19 encephalopathy were cortical signal abnormalities on FLAIR images (37%), accompanied by diffusion reduction, leptomeningeal enhancement and cortical blooming artifacts in some cases. MRI findings in COVID-19 encephalitis, especially when suggesting autoimmune encephalopathy may imply therapeutic interventions, such as immunosuppressive therapy. Recently, progressive clinical improvement along with a reduction of inflammatory CSF parameters has been observed in COVID-19 encephalitis, following high-dose steroid treatment [11] . In summary, a previously undescribed imaging pattern in parainfectious COVID-19 encephalitis is presented that bears a strong resemblance to MRI findings in autoimmune encephalitic syndromes, such as known from epileptic or encephalitis caused by antineuronal antibodies. abstract: nan url: https://www.ncbi.nlm.nih.gov/pubmed/32880721/ doi: 10.1007/s00415-020-10185-y id: cord-000843-e1bn79ui author: nan title: ECR 2011 Book of Abstracts - A - Postgraduate Educational Programme date: 2011-03-01 words: 91224.0 sentences: 4805.0 pages: flesch: 41.0 cache: ./cache/cord-000843-e1bn79ui.txt txt: ./txt/cord-000843-e1bn79ui.txt summary: The role of radiology includes (a) characterisation of sonographically indeterminate adnexal masses, (b) staging as guidance for surgery and treatment planning (including identification of sites of non optimal resectabilty) in suspected ovarian cancer, (c) assessment of recurrent disease, and (d) in selected cases image-guided biopsy. The association of multiple markers of structural and functional imaging (MRI and PET) and the use of advanced computational analysis techniques will allow better management of AD but it needs a broader validation and know the most efficient combination of biomarkers at each stage of the disease, including the preclinical period. Although the basic techniques for DCE-CT have been available for decades, more recently a range of technological advances have contributed to the greater applicability of perfusion CT in the clinical environment including wider CT detectors, shorter gantry rotation times, ''table-toggling'', radiation dose reduction and software corrections for image mis-registration due to respiratory or other patient motion. abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533621/ doi: 10.1007/s13244-011-0078-3 id: cord-000977-ka4261wc author: nan title: ECR 2013 Book of Abstracts - B - Scientific Sessions date: 2013-03-07 words: 132895.0 sentences: 8080.0 pages: flesch: 50.0 cache: ./cache/cord-000977-ka4261wc.txt txt: ./txt/cord-000977-ka4261wc.txt summary: Methods and Materials: Mean attenuation, contrast-to-noise ratio (CNR) and signal-to-noise ratio (SNR) at abdominal aorta, right renal artery (RRA) and left renal artery (LRA) were measured in 24 kidney donors who had undergone CTA with tube current modulation, 120 kVp, filtered back projection reconstruction algorithm (Group A) and were compared with 24 BMI-matched kidney donors who had undergone CTA with automated kVp selection and SAFIRE (Group B Purpose: Cerebral small vessel disease (SVD) is a common cause of cognitive impairment. Overall average score of SSF reconstructed segments was significantly higher compared with STD reconstruction ( Purpose: To evaluate the feasibility and imaging quality of double prospectively ECG-triggered high-pitch spiral acquisition mode for coronary computed tomography angiography (CTCA) in patients with atrial fibrillation (AF). abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666652/ doi: 10.1007/s13244-013-0228-x id: cord-001221-due9tloa author: nan title: ECR 2014, Part A date: 2014-02-27 words: 107848.0 sentences: 5493.0 pages: flesch: 40.0 cache: ./cache/cord-001221-due9tloa.txt txt: ./txt/cord-001221-due9tloa.txt summary: In short: obtaining samples for making an accurate diagnosis and also to know more about its specific biology (biomarkers); IR covers any possibility needed for vascular access; percutaneous needle ablation is the best alternative in selected patients; endovascular embolisation with "vehiculisation" of therapies is an outstanding method for selective treatment, and sometimes precise ablation, of different tumors; IR is a unique way to offer palliation in a wide range of tumoral complications, such as embolisation for bleeding, stenting for vein obstructions or drainage of fluid collections. CT may be useful for osteoid osteoma and MRI is the best imaging technique for further diagnosis and staging by displaying tumour composition and extent of bone marrow involvement, including skip lesions, presence and extent of extraosseous soft tissue mass, and involvement of neurovascular bundle, muscle compartments and adjacent joint. abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948175/ doi: 10.1007/s13244-014-0316-6 id: cord-005105-twsy61oq author: nan title: SIU 2015 Abstracts date: 2015-09-21 words: 124096.0 sentences: 7584.0 pages: flesch: 54.0 cache: ./cache/cord-005105-twsy61oq.txt txt: ./txt/cord-005105-twsy61oq.txt summary: Th e present study is based on a retrospective analysis of a database of over 600 patients (age range 17-57 years) who met the consensus criteria for bacterial prostatitis, 75% of whom had dysuria, 35% perineal discomfort, 60% had obstructive luts, 37% infertility of unknown etiology, 10% erectile dysfunction and 25% recurrent infection of the partner. Further research is needed to determine to assess whether localization of small volume disease on 68Ga-PSMA PET/CT can improve diagnostic algorithms and outcomes in patients with recurrent PCa. Introduction and Objective: To assess long-term results of salvage pelvic lymph node dissection (PLND) in prostate cancer (PC) patients (pts) with biochemical recurrence aft er primary local treatment and confi rmed solitary lymph node (LN) metastases. abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088373/ doi: 10.1007/s00345-015-1684-3 id: cord-006182-kck5e1ry author: nan title: 17th Annual Meeting, Neurocritical Care Society, October 15–18, 2019, Vancouver, Canada date: 2019-10-01 words: 87645.0 sentences: 4817.0 pages: flesch: 46.0 cache: ./cache/cord-006182-kck5e1ry.txt txt: ./txt/cord-006182-kck5e1ry.txt summary: The primary objective of COGiTATE (CppOpt GuIded Therapy Assessment of Target Effectiveness) is to demonstrate feasibility of individualising CPP at CPPopt in TBI patients, expressed as the percentage of monitoring time for which CPP is within 5 mmHg of regularly updated CPPopt targets during the first 5 days of Intensive Care Unit (ICU) admission. Neurocritical care has become increasingly subspecialized.Yet, due to limited availability of dedicated Neurocritical Care units (NCCUs), often patients may need to be admitted to ICUs other than NCCUs. This survey based study was conducted to explore self-reported knowledge in recognizing and managing some common neurological emergencies such as stroke, status epilepticus, raised intracranial pressure etc among critical care nurses at a Comprehensive Stroke Center. Coagulation factor Xa (recombinant), inactivated-Xa inhibitor associated life--factor prothrombin complex concentrate (PCC) was utilized offRetrospective, single center, cohort study including adult intracranial hemorrhage patients who received discharge between efficacy (defined by International Society on Thrombosis and Haemostasis criteria), thrombotic events, ICU and hospital length of stay, and mortality. abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100118/ doi: 10.1007/s12028-019-00857-7 id: cord-006828-i88on326 author: nan title: Abstracts DGRh-Kongress 2013 date: 2013-09-15 words: 30772.0 sentences: 2576.0 pages: flesch: 52.0 cache: ./cache/cord-006828-i88on326.txt txt: ./txt/cord-006828-i88on326.txt summary: Comparing gene expression profiles of yellow fever immunized individuals and active SLE patients it was possible to identify a "common" and an "autoimmune-specific" IFN signature. The inflammatory and profibrotic effects upon Aab stimulation in vitro, and their associations with clinical findings suggest a role for autoantibody-mediated activation of immune cells mediated through the AT1R and ETAR in the pathogenesis or even the onset of the disease. This study was aimed to investigate the humoral and cellular immune response to VZV including assessment of IgG-anti-VZV avidity and VZV-specific reactivity of lymphocytes in RA (n=56) or JIA patients (n=75) on different treatments, including biologic agents, such as anti-tumor-necrosis-factor(TNF)-alpha or anti-interleukin-6 (IL-6) receptor inhibition (tocilizumab), compared to 37 healthy adults (HA) and 41 children (HC). Production of cytokines by B cells in response to TLR9 stimulation inversely correlates with disease activity in SLE-patients abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103148/ doi: 10.1007/s00393-013-1255-1 id: cord-006849-vgjz74ts author: nan title: 27th International Congress of the European Association for Endoscopic Surgery (EAES) Sevilla, Spain, 12–15 June 2019 date: 2019-09-13 words: 222162.0 sentences: 14023.0 pages: flesch: 48.0 cache: ./cache/cord-006849-vgjz74ts.txt txt: ./txt/cord-006849-vgjz74ts.txt summary: Methods: We are performing this procedures within a prospective randomized trial that is design to compare the long term results of LRYGB-B versus the standard laparoscopic Roux-en-Y gastric bypass.The video shows our technique in a case of a 46 years old female with a BMI of 46 Kg/m2. Material and methods: We present a video of the surgical intervention of a 32-year-old patient, with functional dyspepsia, with a casual diagnosis of a pseudocystic mass of the right colon after performing a CT scan: giant diverticulum of the hepatic colon angle with fecaloid content inside it under tension The patient goes to the emergency room for acute abdominal pain, pending colonoscopy, antibiotic treatment is established, and a laparoscopic approach is decided upon after the patient''s evolution. Method: We present the case of a 65-year-old patient with surgical antecedent of laparoscopic low anterior resection due to rectal cancer, presenting in postoperative period an anastomosis leakage with severe peritonitis was identified and a laparotomy with end colostomy was performed. abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103177/ doi: 10.1007/s00464-019-07109-x id: cord-006869-g2q1gpp0 author: nan title: Neurocritical Care Society 7th Annual Meeting date: 2009-10-08 words: 45395.0 sentences: 2661.0 pages: flesch: 49.0 cache: ./cache/cord-006869-g2q1gpp0.txt txt: ./txt/cord-006869-g2q1gpp0.txt summary: This was a pilot study to compare the cerebral neurochemical changes in patients with traumatic brain injury (TBI) who underwent conventional blood glucose level (BGL) control and intensive BGL control with continuous titrated insulin. We studied 14 comatose SAH patients who underwent multimodality neuromonitoring with intracranial pressure (ICP), cerebral microdialysis, and brain tissue oxygen (PbtO 2 ) as part of their clinical care. We studied 46 consecutive comatose patients with subarachnoid or intracerebral hemorrhage, traumatic brain injury, or cardiac arrest who underwent cerebral microdialysis and intracranial pressure monitoring.Continuous insulin infusion was used to maintain target serum glucose levels of 80-120 mg/dl. This suggests that risk of cerebral vasospasm following traumatic brain injury is increased not only in subarachnoid hemorrhage, but also intraparenchymal hemorrhage, and that Rotterdam CT score may be a useful metric for assessing risk of csPTV in severe TBI patients. abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103236/ doi: 10.1007/s12028-009-9282-0 id: cord-006870-f5w6fw6q author: nan title: Abstracts Presented at the Neurocritical Care Society (NCS) 15th Annual Meeting date: 2017-09-19 words: 122221.0 sentences: 6828.0 pages: flesch: 47.0 cache: ./cache/cord-006870-f5w6fw6q.txt txt: ./txt/cord-006870-f5w6fw6q.txt summary: Subjective perceptions of recovery were assessed via responses to the forced-choice dichotomized question, "Do you feel that you have made a complete recovery from the arrest?"Objective outcome measures of recovery included: Repeatable Battery for Neuropsychological Status (RBANS), Modified Lawton Physical Self-Maintenance Scale (L-ADL), Barthel Index (BI), Cerebral Performance Category Scale (CPC), Center for Epidemiological Studies-Depression scale (CES-D), and Post traumatic stress disorder-checklist (PTSD-C). Utilizing data from the Citicoline Brain Injury Treatment (COBRIT) trial, a prospective multicenter study, we identified 224 patients who met the inclusion criteria; 1) placement of an ICP monitoring device, 2) Glasgow coma score (GCS) less than 9, 3) EVD placement prior to arrival or within 6 hours of arrival at the study institution. The objective of this study was to examine the incidence rates of pre-specified medical and neurological ICU complications, and their impact on post-traumatic in-hospital mortality and 12month functional outcomes. abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103238/ doi: 10.1007/s12028-017-0465-9 id: cord-006876-v2m5l5wz author: nan title: Neurocritical Care Society 14(th) Annual Meeting date: 2016-08-11 words: 59719.0 sentences: 3440.0 pages: flesch: 47.0 cache: ./cache/cord-006876-v2m5l5wz.txt txt: ./txt/cord-006876-v2m5l5wz.txt summary: We conducted a prospective cohort study among mild and moderate-severe TBI patients admitted to a level 1 trauma center with these inclusion criteria: 1) Age < 65 years, 2) No severe non-TBI injuries, 3) No prior cardiac disease, and 4) Minimal comorbidities. In most instances, DC has been performed based on neurosurgical evaluation of the patient with or without intracranial pressure (ICP) monitoring and evidence of increased shown variable outcomes in emergency (within 4 hours of injury) neurosurgical procedure in Traumatic Brain Injury (TBI). This is an observational cohort study of adult patients (>18 years) in a 10-bed NSICU at an academic, tertiary care center evaluating quality outcome measures pre-and post-neurointensivists. Intensivists in neuro ICU must consistently assess and treat the non-neurological complications in traumatic brain and spine-injured patients and deliver appropriate care to bring down the mortality and morbidity and improve outcome. abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103251/ doi: 10.1007/s12028-016-0301-7 id: cord-006880-9dgmdtj8 author: nan title: Neurocritical Care Society 10th Annual Meeting: October 4 - 7, 2012 Sheraton Denver Downtown Hotel Denver, Colorado date: 2012-09-19 words: 82351.0 sentences: 4528.0 pages: flesch: 49.0 cache: ./cache/cord-006880-9dgmdtj8.txt txt: ./txt/cord-006880-9dgmdtj8.txt summary: Patients initially comatose after cardiac arrest treated who awoke after therapeutic hypothermia (TH) were evaluated by a neuropsychologist prior to hospital discharge with the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS), a well-validated tool that assesses function in multiple domains compared to standardized normal values. Clinical data including the pre-admission-status, neuroradiological, initial presentation, treatment, and outcome were evaluated through institutional databases, patient''s medical charts and by mailed questionnaires. To determine the differences in hospital outcomes among adult mild traumatic brain injury (TBI) patients where the severity of TBI is defined by Glasgow Coma Scale (GCS) score. Retrospective chart analysis was performed on all adult patients arriving to emergency department with history of fall at a level one trauma center for parameters like vomiting, alteration of consciousness (AOC) & loss of consciousness (LOC) after TBI; post-traumatic amnesia (PTA) and history of seizures before or after injury, along with outcomes such as ICU admission & ICU length of stay. abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103259/ doi: 10.1007/s12028-012-9775-0 id: cord-009713-sxd4t2tz author: nan title: Poster Presentations date: 2020-01-10 words: 43950.0 sentences: 2945.0 pages: flesch: 52.0 cache: ./cache/cord-009713-sxd4t2tz.txt txt: ./txt/cord-009713-sxd4t2tz.txt summary: Poster No. 010 Seizure, developmental and cognitive outcomes in children post hemispherotomy TT TAY 1 , DR REED 2 , VJ JOSAN 3 , SR RUST 4 , JT TAN 5 1 University of Manchester, Manchester, UK; 2 Neuropsychology Team, Paediatric Psychosocial Service, Royal Manchester Children''s Hospital, Manchester, UK; 3 Neurosurgery, Salford Royal NHS Foundation, Manchester, UK; 4 Paediatric Neuropsychology, Royal Manchester Children''s Hospital, Manchester, UK; 5 Paediatric Neurology, Royal Manchester Children''s Hospital, Manchester, UK Introduction: Patients with focal refractory epilepsy secondary to structural hemispheric changes have been shown in retrospective studies to have significantly improved seizure outcomes following hemispheric disconnection. In a univariate analysis of 682 cases with ≥12 months follow-up data, poor final outcome (defined as modified Rankin Scale [mRS] score 3-6) occurred in 30% and was associated with very young or elderly age at onset, movement disorder, decreased consciousness, autonomic dysfunction, mechanical ventilation, higher mRS score in the acute phase, longer hospital stay, extreme delta brush on EEG, abnormal MRI, CSF pleocytosis and elevated CSF protein (all p<0.05). abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7163607/ doi: 10.1111/dmcn.14411 id: cord-009997-oecpqf1j author: nan title: 2018 ASPHO ABSTRACTS date: 2018-03-31 words: 182060.0 sentences: 10342.0 pages: flesch: 48.0 cache: ./cache/cord-009997-oecpqf1j.txt txt: ./txt/cord-009997-oecpqf1j.txt summary: Completed cranial radiation and proceeded to allogeneic stem cell transplant with unrelated cord marrow donor and is disease free at approximately day +200.Case 2: 5 year-old female diagnosed with FLT3 and MLL negative AML and completed treatment per COG AAML1031 study on the low risk arm without Bortezomib. Design/Method: This study was a retrospective chart review that included patients 3 to 23 years old with sickle cell disease type SS and S 0 followed at St. Christopher''s Hospital for Children. Background: Hydroxyurea, chronic blood transfusion, and bone marrow transplantation can reduce complications, and improve survival in sickle cell disease (SCD), but are associated with a significant decisional dilemma because of the inherent risk-benefit tradeoffs, and the lack of comparative studies. Brown University -Hasbro Children''s Hospital, Providence, Rhode Island, United States Background: Despite clinical advances in the treatment of sickle cell disease (SCD) in pediatric and young adult patients, pain remains a significant source of disease-related morbidity. abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7167873/ doi: 10.1002/pbc.27057 id: cord-014687-0am4l5ms author: nan title: SPR 2012 date: 2012-03-29 words: 98592.0 sentences: 5600.0 pages: flesch: 43.0 cache: ./cache/cord-014687-0am4l5ms.txt txt: ./txt/cord-014687-0am4l5ms.txt summary: This presentation will focus on recent developments that have lead to a better understanding of the embryopathogenesis for fibropolycystic liver diseases (including choledochal cysts and Caroli disease), histopathological findings that have led to new classification systems for of pediatric vascular anomalies, technological advances and contrast agents in magnetic resonance imaging that are useful to characterize and limit the differential diagnosis of hepatic masses. Disclosure: Dr. Annapragada has indicated that he is a stock holder and consultant for Marval Biosciences Inc. Paper #: PA-067 Cardiovascular Image Quality Using a Nanoparticle CT Contrast Agent: Preliminary Studies in a Pig Model Rajesh Krishnamurthy, Radiology, Texas Children''s Hospital, rxkrishn@texaschildrens.org; Ketan Ghaghada, Prakash Masand, Abhay Divekar, Eric Hoffman, Ananth Annapragada Purpose or Case Report: Image quality in a separate study using a long circulating, liposomal-based nanoscale blood pool iodinated contrast agent (NCTX) suggests clinical utility in pediatrics, potentially reducing difficulties in contrast-CT of children with congenital heart disease (CHD) including the size of intravenous cannula, need for accurate timing, inability to simultaneously opacify multiple targets of interest (requiring repeated contrast administration and/or repeated imaging). abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080092/ doi: 10.1007/s00247-012-2356-8 id: cord-015352-2d02eq3y author: nan title: ESPR 2017 date: 2017-04-26 words: 82253.0 sentences: 4479.0 pages: flesch: 46.0 cache: ./cache/cord-015352-2d02eq3y.txt txt: ./txt/cord-015352-2d02eq3y.txt summary: Lapierre; Montreal/CA Summary: Objectives: To review the classification of visceroatrial situs To describe the associated cardiac and non-cardiac anomalies To illustrate typical findings in fetuses, neonates and children To discuss the surgical consideration and the long-term follow-up in these patients Abstract: By definition, the type of situs is determined by the relationship between the atria and the adjacent organs. As is often the case, radiology in JIA is all about: knowing your clinicians (i.e. the pretest likelihood for disease) being technically eloquent (e.g. using high-resolution US probes, not delaying post-contrast MRI acquisitions) knowing what is normal (e.g. normal undulations in the articular surface, focal bone marrow signal variation) not being dogmatic about individual observations or measurements interpreting your findings in a clinical context The lecture will demonstrate similarities and differences among joints and modalities in children with variable-severity JIA. abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103096/ doi: 10.1007/s00247-017-3820-2 id: cord-015354-yknwveyz author: nan title: Abstracts_Poster presentations date: 2007-09-18 words: 221428.0 sentences: 13119.0 pages: flesch: 54.0 cache: ./cache/cord-015354-yknwveyz.txt txt: ./txt/cord-015354-yknwveyz.txt summary: Material and Methods: Fourteen individuals (mean age 47±19y range 21-75y; 4W, 10M; including 10 volunteers and 4 patients with angiographically proved CAD) underwent dynamic PET imaging studies (21 frames) at rest and during adenosine stress (0.14mg/kg/min for 6 min) after injection of 1100MBq of 82Rb (Discovery LS, GEMS). Methods:Twenty-nine patients (21 males,8 females;62±11 yrs) with recent AMI were studied.Within 6 days after AMI, the patients were performed Tl-201 R-RD perfusion SPECT using 4 mCi activity.CMR was carried out 5-20 minutes after 0,15 mmol/kg of iv.Gadobutrol injection.Myocardial perfusion and contrast enhancement was analyzed using a 17 segment model.Myocardial perfusion was scored in Tl-201 SPECT as follows:0=normal (70%-100% maximal myocardial activity(mma), 1= 69-50% mma, 2= 49-30% mma ,3=29-10% mma and 4=<10% mma ;Myocardial contrast enhancement on CMR images was graded as:0=no contrast enhancement, 1=hyperenhancement of 0-25% of the wall thickness(WT) 2=hyperenhancement of 26-50 % of the WT, 3=hyperenhancement of 51-75 % of WT and 4=hyperenhancement of 76-100 % of WT.In CMR the existence of microvascular obstruction(MO) was also evaluated.Total segment scores(TSS) in R,RD and CMR for each patient were calculated by summing of 17 segment score values. abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103105/ doi: 10.1007/s00259-007-0544-9 id: cord-015359-gf32a6f1 author: nan title: B scientific sessions (SS) date: 2002 words: 159591.0 sentences: 9768.0 pages: flesch: 51.0 cache: ./cache/cord-015359-gf32a6f1.txt txt: ./txt/cord-015359-gf32a6f1.txt summary: Methods and materials: 73 consecutive patients, clinically considered to have stage 1B tumour (confined to the cervix), underwent MR imaging studies at 1 T, according to the following protocol: fast spin-echo (FSE) T2-weighted, gadoliniumenhanced SE Tl-weighted, and fat-suppressed gadolinium-enhanced SE Tlweighted sequences. Purpose: To describe the radiological (thin section CT) findings correlated to activity and remission in ANCA associated pulmonary-renal small vessel vasculitis (SVV) Material and methods: We used retrospective analysis of 37 CTs, 27 in disease activity (8 first manifestations, 19 relapses) 10 im remission of 17 patients with pulmorenal syndrome (9 Wegener, 4 microscopic polyangiitis-MPA, 3 Churg-Strauss-syndrome, 1 idiopathic crescentic glomerulonephritis following the Chapel Hill classification) 7 women, 10 men, median 65.5 years (34 -84). Varghese, P.R. Mueller; Boston, MA/US Purpose: We sought to determine the incidence of malignancy and to assess a possible role for image guided biopsy of this category of renal masses Materials & methods: Of the 397 renal biopsies performed at our institution between 1991 and 2000; a total of 28 patients with 28 category III lesions, were identified for analysis. abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103164/ doi: 10.1007/s00330-002-0002-9 id: cord-021087-n4epxwn9 author: nan title: ECR – Final Programme: Scientific and Educational Exhibits date: 2004 words: 154170.0 sentences: 9372.0 pages: flesch: 48.0 cache: ./cache/cord-021087-n4epxwn9.txt txt: ./txt/cord-021087-n4epxwn9.txt summary: Conclusions: MRI is useful to identify tumor response to Imatinib Mesylate in advanced GIST as from the early months of therapy with the following indicators of treatment activity: A) Size of lesions; B) signal intensity; C) vascularization; D) amount of degenerative tissue or necrosis; E) presence of peritoneal fluid. Materials and Methods: 34 patients (13 female, 21 male) from two centres with proven myocardial infarction by ECG, clinical and echo criteria underwent stress/ rest Tc99 sestamibi Gated SPECT scanning with a dual headed gamma camera and late contract enhanced MRI on identical 1.5 Tesla scanners in each centre using a protocol which imaged 15 minutes after injection of 0.1 mmol/kg IV gadolinium. These preliminary results illustrate the ability of MRI to assess the integrity of the TFCC and suggests its use as the first imaging method following plain radiography in the evaluation of patients with chronic posttraumatic pain on the ulnar side of the wrist. abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7149010/ doi: 10.1007/s10406-005-0142-5 id: cord-021206-4zyqqgs0 author: nan title: Scientific and Educational Exhibits date: 2007 words: 138669.0 sentences: 8591.0 pages: flesch: 48.0 cache: ./cache/cord-021206-4zyqqgs0.txt txt: ./txt/cord-021206-4zyqqgs0.txt summary: Purpose: To analyze the clinical and imaging fi ndings of BI-RADS category 3 breast lesions by mammographic and ultrasonographic (US) assessment ultimately diagnosed as malignancy in retrospect Methods and Materials: Of 3,207 cases of US-guided core needle biopsy for 4 years, category 3 was given after biopsy, based on mammographic and sonographic evaluation, in 1,099 lesions (41.7%) that were composed of 462 palpable and 637 nonpalpable lesions. Background: Regional kinesis alteration of IVS is associated with different cardiac conditions which may have both pathological and physiological meanings of which the most important are the following: a) left bundle branch block that may determine intra-left ventricular asynchrony and may represent an independent predictor of severe cardiac events in heart failure patients; b) pulmonary embolism that increase right ventricle pressure; c) constrictive pericarditis; d) restrictive cardiomyopathies; e) post-operative cardiac surgery. abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7149153/ doi: 10.1007/s10406-007-0215-8 id: cord-022659-chwk2bs4 author: nan title: Abstracts: Poster session date: 2004-10-08 words: 49153.0 sentences: 2598.0 pages: flesch: 49.0 cache: ./cache/cord-022659-chwk2bs4.txt txt: ./txt/cord-022659-chwk2bs4.txt summary: We investigated the usefulness of informant-based data in Alzheimer''s disease (AD) by comparing caregivers'' subjective evaluations of 83 probable A D patients'' performance on an abbreviated version of the Memory Self-Report Questionnaire to objective evaluations derived from an extensive battery of neuropsychological tests and to clinicians'' evaluations. Compared with 89 subjects (mean age 75.2 yr; 34 men, 55 women) with dementia of the Alzheimer type (DAT), there were no significant group differences for comparable Clinical Dementia Rating stages of dementia for measures of language, Activities of Daily Living, or general cognition. The mean age at onset did not differ significantly between handedness groups (F [ l,lOO] = .82), but the mean duration of symptoms ( Alterations in the optical properties of brain can be used to detect pathological changes in patients with Alzheimer''s disease (AD). abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159508/ doi: 10.1002/ana.410320224 id: cord-023049-fio7cjj5 author: nan title: 2017 Peripheral Nerve Society Meeting July 8–12, 2017 Sitges, Barcelona, Spain date: 2017-06-22 words: 145485.0 sentences: 7436.0 pages: flesch: 48.0 cache: ./cache/cord-023049-fio7cjj5.txt txt: ./txt/cord-023049-fio7cjj5.txt summary: Clinical efficacy (Medical Research Council sum score, 10-m walk, modified Inflammatory Neuropathy Cause and Treatment score, Overall Neuropathy Limitations Scale, Romberg test) and patient-reported outcomes (36-item Short Form Health Survey , Life Quality Index [LQI] ) were assessed at baseline and at regular intervals until the final visit (10-14 months after switching). To explore the issue of early biomarkers in FAP, we performed skin biopsy and compared IENF density with parameters of nerve conduction studies (NCS) and quantitative sensory testing (QST) on 36 subjects (23 men, aged 55.1 ± 11.1 years) with genetic confirmation of TTR-A97S: 17 patients and 19 carriers. Results: The Gly112Ser mutation causing CMT1C is a mild form of CMT, as patients walked on time, had less weakness than those with Charcot-Marie-Tooth Disease type 1A (CMT1A), had a Charcot Marie Tooth neuropathy score (CMTNS) indicative of mild disease, and had faster ulnar and median motor nerve conduction velocities compared to those with CMT1A. abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7166380/ doi: 10.1111/jns.12225 id: cord-023353-2yoz1t6a author: nan title: ABSTRACTS FROM THE 2010 EVDI ANNUAL MEETING date: 2010-12-28 words: 30157.0 sentences: 1720.0 pages: flesch: 48.0 cache: ./cache/cord-023353-2yoz1t6a.txt txt: ./txt/cord-023353-2yoz1t6a.txt summary: 3 Department of Physiology and Biometry, Ghent University, Belgium Introduction/Purpose: The microbubble-based contrast agents for ultrasonography have become more used in recent years in dogs1, and have been reported to be useful in differentiating adenomas from nonadenomatous lesions in human patients with adrenal masses2. Peak intensity Time to Introduction/Purpose: Studies with contrast enhanced ultrasonography (CEUS) on focal splenic lesions have shown discrepancies in accuracy for differentiating benign from malignant lesions.1-3 A speculative explanation for false positives may be the absence of a dual blood supply to the spleen compared to the liver. 1 The aim of the study was to test the hypothesis that the suggested maximum normal kidney size obtained from radiographs is too high and also to evaluate whether breed type (brachycephalic, doliocephalic, mesocephalic), age, gender, weight and body condition of the dog have an impact on kidney size. abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7169298/ doi: 10.1111/j.1740-8261.2010.01774.x ==== make-pages.sh questions [ERIC WAS HERE] ==== make-pages.sh search /data-disk/reader-compute/reader-cord/bin/make-pages.sh: line 77: /data-disk/reader-compute/reader-cord/tmp/search.htm: No such file or directory Traceback (most recent call last): File "/data-disk/reader-compute/reader-cord/bin/tsv2htm-search.py", line 51, in with open( TEMPLATE, 'r' ) as handle : htm = handle.read() FileNotFoundError: [Errno 2] No such file or directory: '/data-disk/reader-compute/reader-cord/tmp/search.htm' ==== make-pages.sh topic modeling corpus Zipping study carrel