id	sid	tid	token	lemma	pos
cord-287670-z6ckhkgg	1	1	key	key	NN
cord-287670-z6ckhkgg	1	2	:	:	:
cord-287670-z6ckhkgg	1	3	cord-287670-z6ckhkgg	cord-287670-z6ckhkgg	NNP
cord-287670-z6ckhkgg	1	4	authors	author	NNS
cord-287670-z6ckhkgg	1	5	:	:	:
cord-287670-z6ckhkgg	1	6	Magrini	Magrini	NNP
cord-287670-z6ckhkgg	1	7	,	,	,
cord-287670-z6ckhkgg	1	8	Elena	Elena	NNP
cord-287670-z6ckhkgg	1	9	;	;	:
cord-287670-z6ckhkgg	1	10	Mantovani	Mantovani	NNP
cord-287670-z6ckhkgg	1	11	,	,	,
cord-287670-z6ckhkgg	1	12	Alberto	Alberto	NNP
cord-287670-z6ckhkgg	1	13	;	;	:
cord-287670-z6ckhkgg	1	14	Garlanda	Garlanda	NNP
cord-287670-z6ckhkgg	1	15	,	,	,
cord-287670-z6ckhkgg	1	16	Cecilia	Cecilia	NNP
cord-287670-z6ckhkgg	1	17	title	title	NN
cord-287670-z6ckhkgg	1	18	:	:	:
cord-287670-z6ckhkgg	1	19	The	the	DT
cord-287670-z6ckhkgg	1	20	Dual	Dual	NNP
cord-287670-z6ckhkgg	1	21	Complexity	Complexity	NNP
cord-287670-z6ckhkgg	1	22	of	of	IN
cord-287670-z6ckhkgg	1	23	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	1	24	in	in	IN
cord-287670-z6ckhkgg	1	25	Health	Health	NNP
cord-287670-z6ckhkgg	1	26	and	and	CC
cord-287670-z6ckhkgg	1	27	Disease	Disease	NNP
cord-287670-z6ckhkgg	1	28	:	:	:
cord-287670-z6ckhkgg	1	29	A	a	DT
cord-287670-z6ckhkgg	1	30	Balancing	Balancing	NNP
cord-287670-z6ckhkgg	1	31	Act	Act	NNP
cord-287670-z6ckhkgg	1	32	?	?	.
cord-287670-z6ckhkgg	2	1	date	date	NN
cord-287670-z6ckhkgg	2	2	:	:	:
cord-287670-z6ckhkgg	2	3	2016	2016	CD
cord-287670-z6ckhkgg	2	4	-	-	HYPH
cord-287670-z6ckhkgg	2	5	06	06	CD
cord-287670-z6ckhkgg	2	6	-	-	SYM
cord-287670-z6ckhkgg	2	7	30	30	CD
cord-287670-z6ckhkgg	2	8	journal	journal	NN
cord-287670-z6ckhkgg	2	9	:	:	:
cord-287670-z6ckhkgg	2	10	Trends	trend	NNS
cord-287670-z6ckhkgg	2	11	in	in	IN
cord-287670-z6ckhkgg	2	12	Molecular	Molecular	NNP
cord-287670-z6ckhkgg	2	13	Medicine	Medicine	NNP
cord-287670-z6ckhkgg	2	14	DOI	DOI	NNP
cord-287670-z6ckhkgg	2	15	:	:	:
cord-287670-z6ckhkgg	2	16	10.1016	10.1016	CD
cord-287670-z6ckhkgg	2	17	/	/	SYM
cord-287670-z6ckhkgg	2	18	j.molmed.2016.04.007	j.molmed.2016.04.007	NN
cord-287670-z6ckhkgg	2	19	sha	sha	NNP
cord-287670-z6ckhkgg	2	20	:	:	:
cord-287670-z6ckhkgg	2	21	d5ebe3c5f63aab796614b995caa0db4ce444ab6f	d5ebe3c5f63aab796614b995caa0db4ce444ab6f	NNP
cord-287670-z6ckhkgg	2	22	doc_id	doc_id	CD
cord-287670-z6ckhkgg	2	23	:	:	:
cord-287670-z6ckhkgg	2	24	287670	287670	CD
cord-287670-z6ckhkgg	2	25	cord_uid	cord_uid	NNS
cord-287670-z6ckhkgg	2	26	:	:	:
cord-287670-z6ckhkgg	3	1	z6ckhkgg	z6ckhkgg	NNP
cord-287670-z6ckhkgg	4	1	The	the	DT
cord-287670-z6ckhkgg	4	2	humoral	humoral	JJ
cord-287670-z6ckhkgg	4	3	arm	arm	NN
cord-287670-z6ckhkgg	4	4	of	of	IN
cord-287670-z6ckhkgg	4	5	innate	innate	JJ
cord-287670-z6ckhkgg	4	6	immunity	immunity	NN
cord-287670-z6ckhkgg	4	7	is	be	VBZ
cord-287670-z6ckhkgg	4	8	complex	complex	JJ
cord-287670-z6ckhkgg	4	9	and	and	CC
cord-287670-z6ckhkgg	4	10	includes	include	VBZ
cord-287670-z6ckhkgg	4	11	various	various	JJ
cord-287670-z6ckhkgg	4	12	molecules	molecule	NNS
cord-287670-z6ckhkgg	4	13	that	that	WDT
cord-287670-z6ckhkgg	4	14	serve	serve	VBP
cord-287670-z6ckhkgg	4	15	as	as	IN
cord-287670-z6ckhkgg	4	16	markers	marker	NNS
cord-287670-z6ckhkgg	4	17	of	of	IN
cord-287670-z6ckhkgg	4	18	inflammation	inflammation	NN
cord-287670-z6ckhkgg	4	19	with	with	IN
cord-287670-z6ckhkgg	4	20	complementary	complementary	JJ
cord-287670-z6ckhkgg	4	21	characteristics	characteristic	NNS
cord-287670-z6ckhkgg	4	22	,	,	,
cord-287670-z6ckhkgg	4	23	such	such	JJ
cord-287670-z6ckhkgg	4	24	as	as	IN
cord-287670-z6ckhkgg	4	25	the	the	DT
cord-287670-z6ckhkgg	4	26	short	short	JJ
cord-287670-z6ckhkgg	4	27	pentraxins	pentraxin	NNS
cord-287670-z6ckhkgg	4	28	C	C	NNP
cord-287670-z6ckhkgg	4	29	-	-	HYPH
cord-287670-z6ckhkgg	4	30	reactive	reactive	JJ
cord-287670-z6ckhkgg	4	31	protein	protein	NN
cord-287670-z6ckhkgg	4	32	(	(	-LRB-
cord-287670-z6ckhkgg	4	33	CRP	CRP	NNP
cord-287670-z6ckhkgg	4	34	)	)	-RRB-
cord-287670-z6ckhkgg	4	35	and	and	CC
cord-287670-z6ckhkgg	4	36	serum	serum	NN
cord-287670-z6ckhkgg	4	37	amyloid	amyloid	NN
cord-287670-z6ckhkgg	4	38	P	P	NNP
cord-287670-z6ckhkgg	4	39	(	(	-LRB-
cord-287670-z6ckhkgg	4	40	SAP	SAP	NNP
cord-287670-z6ckhkgg	4	41	)	)	-RRB-
cord-287670-z6ckhkgg	4	42	and	and	CC
cord-287670-z6ckhkgg	4	43	the	the	DT
cord-287670-z6ckhkgg	4	44	long	long	JJ
cord-287670-z6ckhkgg	4	45	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	4	46	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	4	47	.	.	.
cord-287670-z6ckhkgg	5	1	There	there	EX
cord-287670-z6ckhkgg	5	2	is	be	VBZ
cord-287670-z6ckhkgg	5	3	a	a	DT
cord-287670-z6ckhkgg	5	4	growing	grow	VBG
cord-287670-z6ckhkgg	5	5	amount	amount	NN
cord-287670-z6ckhkgg	5	6	of	of	IN
cord-287670-z6ckhkgg	5	7	evidence	evidence	NN
cord-287670-z6ckhkgg	5	8	–	–	:
cord-287670-z6ckhkgg	5	9	including	include	VBG
cord-287670-z6ckhkgg	5	10	mouse	mouse	NN
cord-287670-z6ckhkgg	5	11	and	and	CC
cord-287670-z6ckhkgg	5	12	human	human	JJ
cord-287670-z6ckhkgg	5	13	genetics	genetic	NNS
cord-287670-z6ckhkgg	5	14	–	–	:
cord-287670-z6ckhkgg	5	15	that	that	WDT
cord-287670-z6ckhkgg	5	16	suggests	suggest	VBZ
cord-287670-z6ckhkgg	5	17	that	that	IN
cord-287670-z6ckhkgg	5	18	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	5	19	is	be	VBZ
cord-287670-z6ckhkgg	5	20	essential	essential	JJ
cord-287670-z6ckhkgg	5	21	in	in	IN
cord-287670-z6ckhkgg	5	22	conferring	confer	VBG
cord-287670-z6ckhkgg	5	23	host	host	NN
cord-287670-z6ckhkgg	5	24	resistance	resistance	NN
cord-287670-z6ckhkgg	5	25	against	against	IN
cord-287670-z6ckhkgg	5	26	selected	select	VBN
cord-287670-z6ckhkgg	5	27	pathogens	pathogen	NNS
cord-287670-z6ckhkgg	5	28	and	and	CC
cord-287670-z6ckhkgg	5	29	,	,	,
cord-287670-z6ckhkgg	5	30	moreover	moreover	RB
cord-287670-z6ckhkgg	5	31	,	,	,
cord-287670-z6ckhkgg	5	32	that	that	IN
cord-287670-z6ckhkgg	5	33	it	-PRON-	PRP
cord-287670-z6ckhkgg	5	34	plays	play	VBZ
cord-287670-z6ckhkgg	5	35	a	a	DT
cord-287670-z6ckhkgg	5	36	dual	dual	JJ
cord-287670-z6ckhkgg	5	37	antagonistic	antagonistic	JJ
cord-287670-z6ckhkgg	5	38	role	role	NN
cord-287670-z6ckhkgg	5	39	in	in	IN
cord-287670-z6ckhkgg	5	40	the	the	DT
cord-287670-z6ckhkgg	5	41	regulation	regulation	NN
cord-287670-z6ckhkgg	5	42	of	of	IN
cord-287670-z6ckhkgg	5	43	inflammation	inflammation	NN
cord-287670-z6ckhkgg	5	44	.	.	.
cord-287670-z6ckhkgg	6	1	Dissection	dissection	NN
cord-287670-z6ckhkgg	6	2	of	of	IN
cord-287670-z6ckhkgg	6	3	such	such	PDT
cord-287670-z6ckhkgg	6	4	a	a	DT
cord-287670-z6ckhkgg	6	5	yin	yin	NN
cord-287670-z6ckhkgg	6	6	-	-	HYPH
cord-287670-z6ckhkgg	6	7	and	and	CC
cord-287670-z6ckhkgg	6	8	-	-	HYPH
cord-287670-z6ckhkgg	6	9	yang	yang	NNP
cord-287670-z6ckhkgg	6	10	role	role	NN
cord-287670-z6ckhkgg	6	11	of	of	IN
cord-287670-z6ckhkgg	6	12	pentraxins	pentraxin	NNS
cord-287670-z6ckhkgg	6	13	in	in	IN
cord-287670-z6ckhkgg	6	14	immunity	immunity	NN
cord-287670-z6ckhkgg	6	15	and	and	CC
cord-287670-z6ckhkgg	6	16	inflammation	inflammation	NN
cord-287670-z6ckhkgg	6	17	is	be	VBZ
cord-287670-z6ckhkgg	6	18	timely	timely	JJ
cord-287670-z6ckhkgg	6	19	and	and	CC
cord-287670-z6ckhkgg	6	20	significant	significant	JJ
cord-287670-z6ckhkgg	6	21	as	as	IN
cord-287670-z6ckhkgg	6	22	it	-PRON-	PRP
cord-287670-z6ckhkgg	6	23	may	may	MD
cord-287670-z6ckhkgg	6	24	pave	pave	VB
cord-287670-z6ckhkgg	6	25	the	the	DT
cord-287670-z6ckhkgg	6	26	way	way	NN
cord-287670-z6ckhkgg	6	27	for	for	IN
cord-287670-z6ckhkgg	6	28	better	well	JJR
cord-287670-z6ckhkgg	6	29	clinical	clinical	JJ
cord-287670-z6ckhkgg	6	30	exploitation	exploitation	NN
cord-287670-z6ckhkgg	6	31	against	against	IN
cord-287670-z6ckhkgg	6	32	various	various	JJ
cord-287670-z6ckhkgg	6	33	diseases	disease	NNS
cord-287670-z6ckhkgg	6	34	.	.	.
cord-287670-z6ckhkgg	7	1	The	the	DT
cord-287670-z6ckhkgg	7	2	Dual	Dual	NNP
cord-287670-z6ckhkgg	7	3	Complexity	Complexity	NNP
cord-287670-z6ckhkgg	7	4	of	of	IN
cord-287670-z6ckhkgg	7	5	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	7	6	in	in	IN
cord-287670-z6ckhkgg	7	7	Health	Health	NNP
cord-287670-z6ckhkgg	7	8	and	and	CC
cord-287670-z6ckhkgg	7	9	Disease	Disease	NNP
cord-287670-z6ckhkgg	7	10	:	:	:
cord-287670-z6ckhkgg	8	1	A	a	DT
cord-287670-z6ckhkgg	8	2	Balancing	Balancing	NNP
cord-287670-z6ckhkgg	8	3	Act	Act	NNP
cord-287670-z6ckhkgg	8	4	?	?	.
cord-287670-z6ckhkgg	9	1	Elena	Elena	NNP
cord-287670-z6ckhkgg	9	2	Magrini	Magrini	NNP
cord-287670-z6ckhkgg	9	3	,	,	,
cord-287670-z6ckhkgg	9	4	1	1	CD
cord-287670-z6ckhkgg	9	5	Alberto	Alberto	NNP
cord-287670-z6ckhkgg	9	6	Mantovani	Mantovani	NNP
cord-287670-z6ckhkgg	9	7	,	,	,
cord-287670-z6ckhkgg	9	8	1,2	1,2	CD
cord-287670-z6ckhkgg	9	9	,	,	,
cord-287670-z6ckhkgg	9	10	*	*	NFP
cord-287670-z6ckhkgg	9	11	and	and	CC
cord-287670-z6ckhkgg	9	12	Cecilia	Cecilia	NNP
cord-287670-z6ckhkgg	9	13	Garlanda	Garlanda	NNP
cord-287670-z6ckhkgg	9	14	1	1	CD
cord-287670-z6ckhkgg	10	1	The	the	DT
cord-287670-z6ckhkgg	10	2	humoral	humoral	JJ
cord-287670-z6ckhkgg	10	3	arm	arm	NN
cord-287670-z6ckhkgg	10	4	of	of	IN
cord-287670-z6ckhkgg	10	5	innate	innate	JJ
cord-287670-z6ckhkgg	10	6	immunity	immunity	NN
cord-287670-z6ckhkgg	10	7	is	be	VBZ
cord-287670-z6ckhkgg	10	8	complex	complex	JJ
cord-287670-z6ckhkgg	10	9	and	and	CC
cord-287670-z6ckhkgg	10	10	includes	include	VBZ
cord-287670-z6ckhkgg	10	11	various	various	JJ
cord-287670-z6ckhkgg	10	12	molecules	molecule	NNS
cord-287670-z6ckhkgg	10	13	that	that	WDT
cord-287670-z6ckhkgg	10	14	serve	serve	VBP
cord-287670-z6ckhkgg	10	15	as	as	IN
cord-287670-z6ckhkgg	10	16	markers	marker	NNS
cord-287670-z6ckhkgg	10	17	of	of	IN
cord-287670-z6ckhkgg	10	18	inflammation	inflammation	NN
cord-287670-z6ckhkgg	10	19	with	with	IN
cord-287670-z6ckhkgg	10	20	complementary	complementary	JJ
cord-287670-z6ckhkgg	10	21	characteristics	characteristic	NNS
cord-287670-z6ckhkgg	10	22	,	,	,
cord-287670-z6ckhkgg	10	23	such	such	JJ
cord-287670-z6ckhkgg	10	24	as	as	IN
cord-287670-z6ckhkgg	10	25	the	the	DT
cord-287670-z6ckhkgg	10	26	short	short	JJ
cord-287670-z6ckhkgg	10	27	pentraxins	pentraxin	NNS
cord-287670-z6ckhkgg	10	28	C	C	NNP
cord-287670-z6ckhkgg	10	29	-	-	HYPH
cord-287670-z6ckhkgg	10	30	reactive	reactive	JJ
cord-287670-z6ckhkgg	10	31	protein	protein	NN
cord-287670-z6ckhkgg	10	32	(	(	-LRB-
cord-287670-z6ckhkgg	10	33	CRP	CRP	NNP
cord-287670-z6ckhkgg	10	34	)	)	-RRB-
cord-287670-z6ckhkgg	10	35	and	and	CC
cord-287670-z6ckhkgg	10	36	serum	serum	NN
cord-287670-z6ckhkgg	10	37	amyloid	amyloid	NN
cord-287670-z6ckhkgg	10	38	P	P	NNP
cord-287670-z6ckhkgg	10	39	(	(	-LRB-
cord-287670-z6ckhkgg	10	40	SAP	SAP	NNP
cord-287670-z6ckhkgg	10	41	)	)	-RRB-
cord-287670-z6ckhkgg	10	42	and	and	CC
cord-287670-z6ckhkgg	10	43	the	the	DT
cord-287670-z6ckhkgg	10	44	long	long	JJ
cord-287670-z6ckhkgg	10	45	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	10	46	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	10	47	.	.	.
cord-287670-z6ckhkgg	11	1	There	there	EX
cord-287670-z6ckhkgg	11	2	is	be	VBZ
cord-287670-z6ckhkgg	11	3	a	a	DT
cord-287670-z6ckhkgg	11	4	growing	grow	VBG
cord-287670-z6ckhkgg	11	5	amount	amount	NN
cord-287670-z6ckhkgg	11	6	of	of	IN
cord-287670-z6ckhkgg	11	7	evidenceincluding	evidenceinclude	VBG
cord-287670-z6ckhkgg	11	8	mouse	mouse	NN
cord-287670-z6ckhkgg	11	9	and	and	CC
cord-287670-z6ckhkgg	11	10	human	human	NN
cord-287670-z6ckhkgg	12	1	geneticsthat	geneticsthat	NNP
cord-287670-z6ckhkgg	12	2	suggests	suggest	VBZ
cord-287670-z6ckhkgg	12	3	that	that	IN
cord-287670-z6ckhkgg	12	4	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	12	5	is	be	VBZ
cord-287670-z6ckhkgg	12	6	essential	essential	JJ
cord-287670-z6ckhkgg	12	7	in	in	IN
cord-287670-z6ckhkgg	12	8	conferring	confer	VBG
cord-287670-z6ckhkgg	12	9	host	host	NN
cord-287670-z6ckhkgg	12	10	resistance	resistance	NN
cord-287670-z6ckhkgg	12	11	against	against	IN
cord-287670-z6ckhkgg	12	12	selected	select	VBN
cord-287670-z6ckhkgg	12	13	pathogens	pathogen	NNS
cord-287670-z6ckhkgg	12	14	and	and	CC
cord-287670-z6ckhkgg	12	15	,	,	,
cord-287670-z6ckhkgg	12	16	moreover	moreover	RB
cord-287670-z6ckhkgg	12	17	,	,	,
cord-287670-z6ckhkgg	12	18	that	that	IN
cord-287670-z6ckhkgg	12	19	it	-PRON-	PRP
cord-287670-z6ckhkgg	12	20	plays	play	VBZ
cord-287670-z6ckhkgg	12	21	a	a	DT
cord-287670-z6ckhkgg	12	22	dual	dual	JJ
cord-287670-z6ckhkgg	12	23	antagonistic	antagonistic	JJ
cord-287670-z6ckhkgg	12	24	role	role	NN
cord-287670-z6ckhkgg	12	25	in	in	IN
cord-287670-z6ckhkgg	12	26	the	the	DT
cord-287670-z6ckhkgg	12	27	regulation	regulation	NN
cord-287670-z6ckhkgg	12	28	of	of	IN
cord-287670-z6ckhkgg	12	29	inflammation	inflammation	NN
cord-287670-z6ckhkgg	12	30	.	.	.
cord-287670-z6ckhkgg	13	1	Dissection	dissection	NN
cord-287670-z6ckhkgg	13	2	of	of	IN
cord-287670-z6ckhkgg	13	3	such	such	PDT
cord-287670-z6ckhkgg	13	4	a	a	DT
cord-287670-z6ckhkgg	13	5	yin	yin	NNP
cord-287670-z6ckhkgg	13	6	-	-	HYPH
cord-287670-z6ckhkgg	13	7	andyang	andyang	NNP
cord-287670-z6ckhkgg	13	8	role	role	NN
cord-287670-z6ckhkgg	13	9	of	of	IN
cord-287670-z6ckhkgg	13	10	pentraxins	pentraxin	NNS
cord-287670-z6ckhkgg	13	11	in	in	IN
cord-287670-z6ckhkgg	13	12	immunity	immunity	NN
cord-287670-z6ckhkgg	13	13	and	and	CC
cord-287670-z6ckhkgg	13	14	inflammation	inflammation	NN
cord-287670-z6ckhkgg	13	15	is	be	VBZ
cord-287670-z6ckhkgg	13	16	timely	timely	JJ
cord-287670-z6ckhkgg	13	17	and	and	CC
cord-287670-z6ckhkgg	13	18	significant	significant	JJ
cord-287670-z6ckhkgg	13	19	as	as	IN
cord-287670-z6ckhkgg	13	20	it	-PRON-	PRP
cord-287670-z6ckhkgg	13	21	may	may	MD
cord-287670-z6ckhkgg	13	22	pave	pave	VB
cord-287670-z6ckhkgg	13	23	the	the	DT
cord-287670-z6ckhkgg	13	24	way	way	NN
cord-287670-z6ckhkgg	13	25	for	for	IN
cord-287670-z6ckhkgg	13	26	better	well	JJR
cord-287670-z6ckhkgg	13	27	clinical	clinical	JJ
cord-287670-z6ckhkgg	13	28	exploitation	exploitation	NN
cord-287670-z6ckhkgg	13	29	against	against	IN
cord-287670-z6ckhkgg	13	30	various	various	JJ
cord-287670-z6ckhkgg	13	31	diseases	disease	NNS
cord-287670-z6ckhkgg	13	32	.	.	.
cord-287670-z6ckhkgg	14	1	The	the	DT
cord-287670-z6ckhkgg	14	2	innate	innate	JJ
cord-287670-z6ckhkgg	14	3	immune	immune	JJ
cord-287670-z6ckhkgg	14	4	response	response	NN
cord-287670-z6ckhkgg	14	5	is	be	VBZ
cord-287670-z6ckhkgg	14	6	the	the	DT
cord-287670-z6ckhkgg	14	7	first	first	JJ
cord-287670-z6ckhkgg	14	8	line	line	NN
cord-287670-z6ckhkgg	14	9	of	of	IN
cord-287670-z6ckhkgg	14	10	defense	defense	NN
cord-287670-z6ckhkgg	14	11	against	against	IN
cord-287670-z6ckhkgg	14	12	invading	invade	VBG
cord-287670-z6ckhkgg	14	13	microbes	microbe	NNS
cord-287670-z6ckhkgg	14	14	and	and	CC
cord-287670-z6ckhkgg	14	15	tissue	tissue	NN
cord-287670-z6ckhkgg	14	16	damage	damage	NN
cord-287670-z6ckhkgg	14	17	and	and	CC
cord-287670-z6ckhkgg	14	18	comprises	comprise	VBZ
cord-287670-z6ckhkgg	14	19	both	both	CC
cord-287670-z6ckhkgg	14	20	a	a	DT
cord-287670-z6ckhkgg	14	21	cellular	cellular	NN
cord-287670-z6ckhkgg	14	22	and	and	CC
cord-287670-z6ckhkgg	14	23	a	a	DT
cord-287670-z6ckhkgg	14	24	humoral	humoral	JJ
cord-287670-z6ckhkgg	14	25	arm	arm	NN
cord-287670-z6ckhkgg	14	26	.	.	.
cord-287670-z6ckhkgg	15	1	Sensing	sensing	NN
cord-287670-z6ckhkgg	15	2	of	of	IN
cord-287670-z6ckhkgg	15	3	microbes	microbe	NNS
cord-287670-z6ckhkgg	15	4	and	and	CC
cord-287670-z6ckhkgg	15	5	tissue	tissue	NN
cord-287670-z6ckhkgg	15	6	injury	injury	NN
cord-287670-z6ckhkgg	15	7	through	through	IN
cord-287670-z6ckhkgg	15	8	pattern	pattern	NN
cord-287670-z6ckhkgg	15	9	recognition	recognition	NN
cord-287670-z6ckhkgg	15	10	molecules	molecule	NNS
cord-287670-z6ckhkgg	15	11	(	(	-LRB-
cord-287670-z6ckhkgg	15	12	PRMs	prm	NNS
cord-287670-z6ckhkgg	15	13	)	)	-RRB-
cord-287670-z6ckhkgg	15	14	(	(	-LRB-
cord-287670-z6ckhkgg	15	15	see	see	VB
cord-287670-z6ckhkgg	15	16	Glossary	Glossary	NNP
cord-287670-z6ckhkgg	15	17	)	)	-RRB-
cord-287670-z6ckhkgg	15	18	triggers	trigger	VBZ
cord-287670-z6ckhkgg	15	19	a	a	DT
cord-287670-z6ckhkgg	15	20	complex	complex	JJ
cord-287670-z6ckhkgg	15	21	response	response	NN
cord-287670-z6ckhkgg	15	22	in	in	IN
cord-287670-z6ckhkgg	15	23	the	the	DT
cord-287670-z6ckhkgg	15	24	organism	organism	NN
cord-287670-z6ckhkgg	15	25	that	that	WDT
cord-287670-z6ckhkgg	15	26	includes	include	VBZ
cord-287670-z6ckhkgg	15	27	the	the	DT
cord-287670-z6ckhkgg	15	28	production	production	NN
cord-287670-z6ckhkgg	15	29	of	of	IN
cord-287670-z6ckhkgg	15	30	inflammatory	inflammatory	JJ
cord-287670-z6ckhkgg	15	31	cytokines	cytokine	NNS
cord-287670-z6ckhkgg	15	32	,	,	,
cord-287670-z6ckhkgg	15	33	the	the	DT
cord-287670-z6ckhkgg	15	34	activation	activation	NN
cord-287670-z6ckhkgg	15	35	of	of	IN
cord-287670-z6ckhkgg	15	36	the	the	DT
cord-287670-z6ckhkgg	15	37	acute	acute	JJ
cord-287670-z6ckhkgg	15	38	phase	phase	NN
cord-287670-z6ckhkgg	15	39	response	response	NN
cord-287670-z6ckhkgg	15	40	,	,	,
cord-287670-z6ckhkgg	15	41	and	and	CC
cord-287670-z6ckhkgg	15	42	leukocyte	leukocyte	NN
cord-287670-z6ckhkgg	15	43	recruitment	recruitment	NN
cord-287670-z6ckhkgg	15	44	and	and	CC
cord-287670-z6ckhkgg	15	45	polarization	polarization	NN
cord-287670-z6ckhkgg	15	46	[	[	-LRB-
cord-287670-z6ckhkgg	15	47	1	1	CD
cord-287670-z6ckhkgg	15	48	,	,	,
cord-287670-z6ckhkgg	15	49	2	2	CD
cord-287670-z6ckhkgg	15	50	]	]	-RRB-
cord-287670-z6ckhkgg	15	51	.	.	.
cord-287670-z6ckhkgg	16	1	This	this	DT
cord-287670-z6ckhkgg	16	2	response	response	NN
cord-287670-z6ckhkgg	16	3	has	have	VBZ
cord-287670-z6ckhkgg	16	4	general	general	JJ
cord-287670-z6ckhkgg	16	5	significance	significance	NN
cord-287670-z6ckhkgg	16	6	in	in	IN
cord-287670-z6ckhkgg	16	7	defense	defense	NN
cord-287670-z6ckhkgg	16	8	and	and	CC
cord-287670-z6ckhkgg	16	9	orchestration	orchestration	NN
cord-287670-z6ckhkgg	16	10	of	of	IN
cord-287670-z6ckhkgg	16	11	tissue	tissue	NN
cord-287670-z6ckhkgg	16	12	repair	repair	NN
cord-287670-z6ckhkgg	16	13	;	;	:
cord-287670-z6ckhkgg	16	14	however	however	RB
cord-287670-z6ckhkgg	16	15	,	,	,
cord-287670-z6ckhkgg	16	16	it	-PRON-	PRP
cord-287670-z6ckhkgg	16	17	is	be	VBZ
cord-287670-z6ckhkgg	16	18	potentially	potentially	RB
cord-287670-z6ckhkgg	16	19	part	part	NN
cord-287670-z6ckhkgg	16	20	of	of	IN
cord-287670-z6ckhkgg	16	21	the	the	DT
cord-287670-z6ckhkgg	16	22	pathogenic	pathogenic	JJ
cord-287670-z6ckhkgg	16	23	mechanisms	mechanism	NNS
cord-287670-z6ckhkgg	16	24	associated	associate	VBN
cord-287670-z6ckhkgg	16	25	with	with	IN
cord-287670-z6ckhkgg	16	26	the	the	DT
cord-287670-z6ckhkgg	16	27	original	original	JJ
cord-287670-z6ckhkgg	16	28	cause	cause	NN
cord-287670-z6ckhkgg	16	29	of	of	IN
cord-287670-z6ckhkgg	16	30	a	a	DT
cord-287670-z6ckhkgg	16	31	particular	particular	JJ
cord-287670-z6ckhkgg	16	32	diseasefor	diseasefor	NN
cord-287670-z6ckhkgg	16	33	instance	instance	NN
cord-287670-z6ckhkgg	16	34	,	,	,
cord-287670-z6ckhkgg	16	35	in	in	IN
cord-287670-z6ckhkgg	16	36	sepsis	sepsis	NN
cord-287670-z6ckhkgg	16	37	or	or	CC
cord-287670-z6ckhkgg	16	38	in	in	IN
cord-287670-z6ckhkgg	16	39	chronic	chronic	JJ
cord-287670-z6ckhkgg	16	40	inflammatory	inflammatory	JJ
cord-287670-z6ckhkgg	16	41	diseases	disease	NNS
cord-287670-z6ckhkgg	16	42	such	such	JJ
cord-287670-z6ckhkgg	16	43	as	as	IN
cord-287670-z6ckhkgg	16	44	arthritis	arthritis	NN
cord-287670-z6ckhkgg	16	45	.	.	.
cord-287670-z6ckhkgg	17	1	The	the	DT
cord-287670-z6ckhkgg	17	2	cellular	cellular	JJ
cord-287670-z6ckhkgg	17	3	arm	arm	NN
cord-287670-z6ckhkgg	17	4	of	of	IN
cord-287670-z6ckhkgg	17	5	innate	innate	JJ
cord-287670-z6ckhkgg	17	6	immunity	immunity	NN
cord-287670-z6ckhkgg	17	7	comprises	comprise	VBZ
cord-287670-z6ckhkgg	17	8	cell	cell	NN
cord-287670-z6ckhkgg	17	9	-	-	HYPH
cord-287670-z6ckhkgg	17	10	associated	associate	VBN
cord-287670-z6ckhkgg	17	11	PRMs	prm	NNS
cord-287670-z6ckhkgg	17	12	located	locate	VBN
cord-287670-z6ckhkgg	17	13	in	in	IN
cord-287670-z6ckhkgg	17	14	different	different	JJ
cord-287670-z6ckhkgg	17	15	cellular	cellular	JJ
cord-287670-z6ckhkgg	17	16	compartments	compartment	NNS
cord-287670-z6ckhkgg	17	17	(	(	-LRB-
cord-287670-z6ckhkgg	17	18	plasma	plasma	NN
cord-287670-z6ckhkgg	17	19	membrane	membrane	NN
cord-287670-z6ckhkgg	17	20	,	,	,
cord-287670-z6ckhkgg	17	21	endosomes	endosome	NNS
cord-287670-z6ckhkgg	17	22	,	,	,
cord-287670-z6ckhkgg	17	23	cytoplasm	cytoplasm	NN
cord-287670-z6ckhkgg	17	24	)	)	-RRB-
cord-287670-z6ckhkgg	17	25	belonging	belong	VBG
cord-287670-z6ckhkgg	17	26	to	to	IN
cord-287670-z6ckhkgg	17	27	different	different	JJ
cord-287670-z6ckhkgg	17	28	molecular	molecular	JJ
cord-287670-z6ckhkgg	17	29	classes	class	NNS
cord-287670-z6ckhkgg	17	30	,	,	,
cord-287670-z6ckhkgg	17	31	such	such	JJ
cord-287670-z6ckhkgg	17	32	as	as	IN
cord-287670-z6ckhkgg	17	33	the	the	DT
cord-287670-z6ckhkgg	17	34	toll	toll	NN
cord-287670-z6ckhkgg	17	35	-	-	HYPH
cord-287670-z6ckhkgg	17	36	like	like	JJ
cord-287670-z6ckhkgg	17	37	receptors	receptor	NNS
cord-287670-z6ckhkgg	17	38	(	(	-LRB-
cord-287670-z6ckhkgg	17	39	TLRs	TLRs	NNP
cord-287670-z6ckhkgg	17	40	)	)	-RRB-
cord-287670-z6ckhkgg	17	41	,	,	,
cord-287670-z6ckhkgg	17	42	the	the	DT
cord-287670-z6ckhkgg	17	43	nucleotide	nucleotide	RB
cord-287670-z6ckhkgg	17	44	-	-	HYPH
cord-287670-z6ckhkgg	17	45	binding	bind	VBG
cord-287670-z6ckhkgg	17	46	oligomerization	oligomerization	NN
cord-287670-z6ckhkgg	17	47	domain	domain	NN
cord-287670-z6ckhkgg	17	48	(	(	-LRB-
cord-287670-z6ckhkgg	17	49	NOD	NOD	NNP
cord-287670-z6ckhkgg	17	50	)	)	-RRB-
cord-287670-z6ckhkgg	17	51	,	,	,
cord-287670-z6ckhkgg	17	52	and	and	CC
cord-287670-z6ckhkgg	17	53	RIG	rig	NN
cord-287670-z6ckhkgg	17	54	-	-	HYPH
cord-287670-z6ckhkgg	17	55	like	like	JJ
cord-287670-z6ckhkgg	17	56	receptors	receptor	NNS
cord-287670-z6ckhkgg	17	57	,	,	,
cord-287670-z6ckhkgg	17	58	as	as	RB
cord-287670-z6ckhkgg	17	59	well	well	RB
cord-287670-z6ckhkgg	17	60	as	as	IN
cord-287670-z6ckhkgg	17	61	the	the	DT
cord-287670-z6ckhkgg	17	62	scavenger	scavenger	NN
cord-287670-z6ckhkgg	17	63	receptors	receptor	NNS
cord-287670-z6ckhkgg	17	64	.	.	.
cord-287670-z6ckhkgg	18	1	The	the	DT
cord-287670-z6ckhkgg	18	2	humoral	humoral	JJ
cord-287670-z6ckhkgg	18	3	arm	arm	NN
cord-287670-z6ckhkgg	18	4	of	of	IN
cord-287670-z6ckhkgg	18	5	innate	innate	JJ
cord-287670-z6ckhkgg	18	6	immunity	immunity	NN
cord-287670-z6ckhkgg	18	7	includes	include	VBZ
cord-287670-z6ckhkgg	18	8	biochemically	biochemically	RB
cord-287670-z6ckhkgg	18	9	heterogeneous	heterogeneous	JJ
cord-287670-z6ckhkgg	18	10	molecules	molecule	NNS
cord-287670-z6ckhkgg	18	11	such	such	JJ
cord-287670-z6ckhkgg	18	12	as	as	IN
cord-287670-z6ckhkgg	18	13	the	the	DT
cord-287670-z6ckhkgg	18	14	classic	classic	JJ
cord-287670-z6ckhkgg	18	15	short	short	JJ
cord-287670-z6ckhkgg	18	16	pentraxins	pentraxin	NNS
cord-287670-z6ckhkgg	18	17	CRP	CRP	NNP
cord-287670-z6ckhkgg	18	18	)	)	-RRB-
cord-287670-z6ckhkgg	18	19	and	and	CC
cord-287670-z6ckhkgg	18	20	SAP	SAP	NNP
cord-287670-z6ckhkgg	18	21	,	,	,
cord-287670-z6ckhkgg	18	22	the	the	DT
cord-287670-z6ckhkgg	18	23	long	long	JJ
cord-287670-z6ckhkgg	18	24	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	18	25	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	18	26	,	,	,
cord-287670-z6ckhkgg	18	27	complement	complement	NN
cord-287670-z6ckhkgg	18	28	recognition	recognition	NN
cord-287670-z6ckhkgg	18	29	molecules	molecule	NNS
cord-287670-z6ckhkgg	18	30	such	such	JJ
cord-287670-z6ckhkgg	18	31	as	as	IN
cord-287670-z6ckhkgg	18	32	C1q	C1q	NNP
cord-287670-z6ckhkgg	18	33	and	and	CC
cord-287670-z6ckhkgg	18	34	ficolins	ficolin	NNS
cord-287670-z6ckhkgg	18	35	,	,	,
cord-287670-z6ckhkgg	18	36	and	and	CC
cord-287670-z6ckhkgg	18	37	the	the	DT
cord-287670-z6ckhkgg	18	38	collectins	collectin	NNS
cord-287670-z6ckhkgg	18	39	.	.	.
cord-287670-z6ckhkgg	19	1	The	the	DT
cord-287670-z6ckhkgg	19	2	activation	activation	NN
cord-287670-z6ckhkgg	19	3	of	of	IN
cord-287670-z6ckhkgg	19	4	such	such	JJ
cord-287670-z6ckhkgg	19	5	molecules	molecule	NNS
cord-287670-z6ckhkgg	19	6	represents	represent	VBZ
cord-287670-z6ckhkgg	19	7	an	an	DT
cord-287670-z6ckhkgg	19	8	important	important	JJ
cord-287670-z6ckhkgg	19	9	component	component	NN
cord-287670-z6ckhkgg	19	10	of	of	IN
cord-287670-z6ckhkgg	19	11	the	the	DT
cord-287670-z6ckhkgg	19	12	host	host	NN
cord-287670-z6ckhkgg	19	13	response	response	NN
cord-287670-z6ckhkgg	19	14	against	against	IN
cord-287670-z6ckhkgg	19	15	invading	invade	VBG
cord-287670-z6ckhkgg	19	16	microbes	microbe	NNS
cord-287670-z6ckhkgg	19	17	or	or	CC
cord-287670-z6ckhkgg	19	18	tissue	tissue	NN
cord-287670-z6ckhkgg	19	19	injury	injury	NN
cord-287670-z6ckhkgg	19	20	[	[	-LRB-
cord-287670-z6ckhkgg	19	21	3	3	CD
cord-287670-z6ckhkgg	19	22	]	]	-RRB-
cord-287670-z6ckhkgg	19	23	.	.	.
cord-287670-z6ckhkgg	20	1	These	these	DT
cord-287670-z6ckhkgg	20	2	fluid	fluid	JJ
cord-287670-z6ckhkgg	20	3	-	-	HYPH
cord-287670-z6ckhkgg	20	4	phase	phase	NN
cord-287670-z6ckhkgg	20	5	PRMs	prms	NN
cord-287670-z6ckhkgg	20	6	harbor	harbor	NN
cord-287670-z6ckhkgg	20	7	antibody	antibody	NN
cord-287670-z6ckhkgg	20	8	-	-	HYPH
cord-287670-z6ckhkgg	20	9	like	like	JJ
cord-287670-z6ckhkgg	20	10	properties	property	NNS
cord-287670-z6ckhkgg	20	11	,	,	,
cord-287670-z6ckhkgg	20	12	recognizing	recognize	VBG
cord-287670-z6ckhkgg	20	13	microbial	microbial	JJ
cord-287670-z6ckhkgg	20	14	moieties	moiety	NNS
cord-287670-z6ckhkgg	20	15	,	,	,
cord-287670-z6ckhkgg	20	16	exhibiting	exhibit	VBG
cord-287670-z6ckhkgg	20	17	opsonic	opsonic	JJ
cord-287670-z6ckhkgg	20	18	activity	activity	NN
cord-287670-z6ckhkgg	20	19	,	,	,
cord-287670-z6ckhkgg	20	20	and	and	CC
cord-287670-z6ckhkgg	20	21	activating	activate	VBG
cord-287670-z6ckhkgg	20	22	and	and	CC
cord-287670-z6ckhkgg	20	23	regulating	regulate	VBG
cord-287670-z6ckhkgg	20	24	the	the	DT
cord-287670-z6ckhkgg	20	25	complement	complement	NN
cord-287670-z6ckhkgg	20	26	cascade	cascade	NN
cord-287670-z6ckhkgg	20	27	[	[	-LRB-
cord-287670-z6ckhkgg	20	28	4	4	CD
cord-287670-z6ckhkgg	20	29	]	]	-RRB-
cord-287670-z6ckhkgg	20	30	,	,	,
cord-287670-z6ckhkgg	20	31	as	as	RB
cord-287670-z6ckhkgg	20	32	well	well	RB
cord-287670-z6ckhkgg	20	33	as	as	IN
cord-287670-z6ckhkgg	20	34	interacting	interact	VBG
cord-287670-z6ckhkgg	20	35	with	with	IN
cord-287670-z6ckhkgg	20	36	extracellular	extracellular	JJ
cord-287670-z6ckhkgg	20	37	matrix	matrix	NN
cord-287670-z6ckhkgg	20	38	(	(	-LRB-
cord-287670-z6ckhkgg	20	39	ECM	ECM	NNP
cord-287670-z6ckhkgg	20	40	)	)	-RRB-
cord-287670-z6ckhkgg	20	41	components	component	NNS
cord-287670-z6ckhkgg	20	42	[	[	-LRB-
cord-287670-z6ckhkgg	20	43	5	5	CD
cord-287670-z6ckhkgg	20	44	]	]	-RRB-
cord-287670-z6ckhkgg	20	45	.	.	.
cord-287670-z6ckhkgg	21	1	The	the	DT
cord-287670-z6ckhkgg	21	2	expression	expression	NN
cord-287670-z6ckhkgg	21	3	of	of	IN
cord-287670-z6ckhkgg	21	4	humoral	humoral	JJ
cord-287670-z6ckhkgg	21	5	PRMs	prm	NNS
cord-287670-z6ckhkgg	21	6	is	be	VBZ
cord-287670-z6ckhkgg	21	7	induced	induce	VBN
cord-287670-z6ckhkgg	21	8	following	follow	VBG
cord-287670-z6ckhkgg	21	9	infection	infection	NN
cord-287670-z6ckhkgg	21	10	or	or	CC
cord-287670-z6ckhkgg	21	11	injury	injury	NN
cord-287670-z6ckhkgg	21	12	in	in	IN
cord-287670-z6ckhkgg	21	13	various	various	JJ
cord-287670-z6ckhkgg	21	14	cell	cell	NN
cord-287670-z6ckhkgg	21	15	types	type	NNS
cord-287670-z6ckhkgg	21	16	and	and	CC
cord-287670-z6ckhkgg	21	17	with	with	IN
cord-287670-z6ckhkgg	21	18	different	different	JJ
cord-287670-z6ckhkgg	21	19	kinetics	kinetic	NNS
cord-287670-z6ckhkgg	21	20	,	,	,
cord-287670-z6ckhkgg	21	21	thus	thus	RB
cord-287670-z6ckhkgg	21	22	providing	provide	VBG
cord-287670-z6ckhkgg	21	23	a	a	DT
cord-287670-z6ckhkgg	21	24	continuous	continuous	JJ
cord-287670-z6ckhkgg	21	25	presence	presence	NN
cord-287670-z6ckhkgg	21	26	of	of	IN
cord-287670-z6ckhkgg	21	27	these	these	DT
cord-287670-z6ckhkgg	21	28	molecules	molecule	NNS
cord-287670-z6ckhkgg	21	29	both	both	CC
cord-287670-z6ckhkgg	21	30	in	in	IN
cord-287670-z6ckhkgg	21	31	the	the	DT
cord-287670-z6ckhkgg	21	32	circulation	circulation	NN
cord-287670-z6ckhkgg	21	33	and	and	CC
cord-287670-z6ckhkgg	21	34	in	in	IN
cord-287670-z6ckhkgg	21	35	tissues	tissue	NNS
cord-287670-z6ckhkgg	21	36	[	[	-LRB-
cord-287670-z6ckhkgg	21	37	3	3	CD
cord-287670-z6ckhkgg	21	38	]	]	-RRB-
cord-287670-z6ckhkgg	21	39	.	.	.
cord-287670-z6ckhkgg	22	1	The	the	DT
cord-287670-z6ckhkgg	22	2	liver	liver	NN
cord-287670-z6ckhkgg	22	3	supports	support	VBZ
cord-287670-z6ckhkgg	22	4	the	the	DT
cord-287670-z6ckhkgg	22	5	expression	expression	NN
cord-287670-z6ckhkgg	22	6	and	and	CC
cord-287670-z6ckhkgg	22	7	production	production	NN
cord-287670-z6ckhkgg	22	8	of	of	IN
cord-287670-z6ckhkgg	22	9	short	short	JJ
cord-287670-z6ckhkgg	22	10	pentraxins	pentraxin	NNS
cord-287670-z6ckhkgg	22	11	systemically	systemically	RB
cord-287670-z6ckhkgg	22	12	.	.	.
cord-287670-z6ckhkgg	23	1	Other	other	JJ
cord-287670-z6ckhkgg	23	2	cell	cell	NN
cord-287670-z6ckhkgg	23	3	types	type	NNS
cord-287670-z6ckhkgg	23	4	,	,	,
cord-287670-z6ckhkgg	23	5	particularly	particularly	RB
cord-287670-z6ckhkgg	23	6	macrophages	macrophage	NNS
cord-287670-z6ckhkgg	23	7	,	,	,
cord-287670-z6ckhkgg	23	8	dendritic	dendritic	JJ
cord-287670-z6ckhkgg	23	9	cells	cell	NNS
cord-287670-z6ckhkgg	23	10	(	(	-LRB-
cord-287670-z6ckhkgg	23	11	DCs	DCs	NNP
cord-287670-z6ckhkgg	23	12	)	)	-RRB-
cord-287670-z6ckhkgg	23	13	,	,	,
cord-287670-z6ckhkgg	23	14	and	and	CC
cord-287670-z6ckhkgg	23	15	endothelial	endothelial	JJ
cord-287670-z6ckhkgg	23	16	cells	cell	NNS
cord-287670-z6ckhkgg	23	17	(	(	-LRB-
cord-287670-z6ckhkgg	23	18	ECs	ec	NNS
cord-287670-z6ckhkgg	23	19	)	)	-RRB-
cord-287670-z6ckhkgg	23	20	,	,	,
cord-287670-z6ckhkgg	23	21	produce	produce	VBP
cord-287670-z6ckhkgg	23	22	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	23	23	in	in	IN
cord-287670-z6ckhkgg	23	24	a	a	DT
cord-287670-z6ckhkgg	23	25	gene	gene	NN
cord-287670-z6ckhkgg	23	26	expression	expression	NN
cord-287670-z6ckhkgg	23	27	-	-	HYPH
cord-287670-z6ckhkgg	23	28	dependent	dependent	JJ
cord-287670-z6ckhkgg	23	29	fashion	fashion	NN
cord-287670-z6ckhkgg	23	30	[	[	-LRB-
cord-287670-z6ckhkgg	23	31	4	4	CD
cord-287670-z6ckhkgg	23	32	]	]	-RRB-
cord-287670-z6ckhkgg	23	33	.	.	.
cord-287670-z6ckhkgg	24	1	Finally	finally	RB
cord-287670-z6ckhkgg	24	2	,	,	,
cord-287670-z6ckhkgg	24	3	neutrophils	neutrophil	NNS
cord-287670-z6ckhkgg	24	4	act	act	VBP
cord-287670-z6ckhkgg	24	5	as	as	IN
cord-287670-z6ckhkgg	24	6	a	a	DT
cord-287670-z6ckhkgg	24	7	reservoir	reservoir	NN
cord-287670-z6ckhkgg	24	8	of	of	IN
cord-287670-z6ckhkgg	24	9	ready	ready	RB
cord-287670-z6ckhkgg	24	10	-	-	HYPH
cord-287670-z6ckhkgg	24	11	made	make	VBN
cord-287670-z6ckhkgg	24	12	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	24	13	,	,	,
cord-287670-z6ckhkgg	24	14	rapidly	rapidly	RB
cord-287670-z6ckhkgg	24	15	released	release	VBN
cord-287670-z6ckhkgg	24	16	within	within	IN
cord-287670-z6ckhkgg	24	17	minutes	minute	NNS
cord-287670-z6ckhkgg	24	18	to	to	IN
cord-287670-z6ckhkgg	24	19	sites	site	NNS
cord-287670-z6ckhkgg	24	20	where	where	WRB
cord-287670-z6ckhkgg	24	21	tissue	tissue	NN
cord-287670-z6ckhkgg	24	22	damage	damage	NN
cord-287670-z6ckhkgg	24	23	or	or	CC
cord-287670-z6ckhkgg	24	24	microbial	microbial	JJ
cord-287670-z6ckhkgg	24	25	stimulation	stimulation	NN
cord-287670-z6ckhkgg	24	26	are	be	VBP
cord-287670-z6ckhkgg	24	27	occurring	occur	VBG
cord-287670-z6ckhkgg	24	28	,	,	,
cord-287670-z6ckhkgg	24	29	thus	thus	RB
cord-287670-z6ckhkgg	24	30	representing	represent	VBG
cord-287670-z6ckhkgg	24	31	a	a	DT
cord-287670-z6ckhkgg	24	32	primary	primary	JJ
cord-287670-z6ckhkgg	24	33	source	source	NN
cord-287670-z6ckhkgg	24	34	of	of	IN
cord-287670-z6ckhkgg	24	35	soluble	soluble	JJ
cord-287670-z6ckhkgg	24	36	PRMs	prm	NNS
cord-287670-z6ckhkgg	24	37	[	[	-LRB-
cord-287670-z6ckhkgg	24	38	6	6	CD
cord-287670-z6ckhkgg	24	39	]	]	-RRB-
cord-287670-z6ckhkgg	24	40	.	.	.
cord-287670-z6ckhkgg	25	1	The	the	DT
cord-287670-z6ckhkgg	25	2	long	long	JJ
cord-287670-z6ckhkgg	25	3	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	25	4	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	25	5	is	be	VBZ
cord-287670-z6ckhkgg	25	6	an	an	DT
cord-287670-z6ckhkgg	25	7	essential	essential	JJ
cord-287670-z6ckhkgg	25	8	component	component	NN
cord-287670-z6ckhkgg	25	9	of	of	IN
cord-287670-z6ckhkgg	25	10	humoral	humoral	JJ
cord-287670-z6ckhkgg	25	11	innate	innate	JJ
cord-287670-z6ckhkgg	25	12	immunity	immunity	NN
cord-287670-z6ckhkgg	25	13	and	and	CC
cord-287670-z6ckhkgg	25	14	plays	play	VBZ
cord-287670-z6ckhkgg	25	15	a	a	DT
cord-287670-z6ckhkgg	25	16	role	role	NN
cord-287670-z6ckhkgg	25	17	in	in	IN
cord-287670-z6ckhkgg	25	18	the	the	DT
cord-287670-z6ckhkgg	25	19	regulation	regulation	NN
cord-287670-z6ckhkgg	25	20	of	of	IN
cord-287670-z6ckhkgg	25	21	inflammation	inflammation	NN
cord-287670-z6ckhkgg	25	22	.	.	.
cord-287670-z6ckhkgg	26	1	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	26	2	has	have	VBZ
cord-287670-z6ckhkgg	26	3	complex	complex	JJ
cord-287670-z6ckhkgg	26	4	effects	effect	NNS
cord-287670-z6ckhkgg	26	5	on	on	IN
cord-287670-z6ckhkgg	26	6	the	the	DT
cord-287670-z6ckhkgg	26	7	vasculature	vasculature	NN
cord-287670-z6ckhkgg	26	8	,	,	,
cord-287670-z6ckhkgg	26	9	including	include	VBG
cord-287670-z6ckhkgg	26	10	an	an	DT
cord-287670-z6ckhkgg	26	11	interaction	interaction	NN
cord-287670-z6ckhkgg	26	12	with	with	IN
cord-287670-z6ckhkgg	26	13	the	the	DT
cord-287670-z6ckhkgg	26	14	angiogenic	angiogenic	JJ
cord-287670-z6ckhkgg	26	15	growth	growth	NN
cord-287670-z6ckhkgg	26	16	factor	factor	NN
cord-287670-z6ckhkgg	26	17	FGF2	FGF2	NNP
cord-287670-z6ckhkgg	26	18	and	and	CC
cord-287670-z6ckhkgg	26	19	the	the	DT
cord-287670-z6ckhkgg	26	20	regulation	regulation	NN
cord-287670-z6ckhkgg	26	21	of	of	IN
cord-287670-z6ckhkgg	26	22	vessel	vessel	NN
cord-287670-z6ckhkgg	26	23	wall	wall	NN
cord-287670-z6ckhkgg	26	24	tone	tone	NN
cord-287670-z6ckhkgg	26	25	.	.	.
cord-287670-z6ckhkgg	27	1	By	by	IN
cord-287670-z6ckhkgg	27	2	modulating	modulate	VBG
cord-287670-z6ckhkgg	27	3	complement	complement	NN
cord-287670-z6ckhkgg	27	4	-	-	HYPH
cord-287670-z6ckhkgg	27	5	driven	drive	VBN
cord-287670-z6ckhkgg	27	6	inflammation	inflammation	NN
cord-287670-z6ckhkgg	27	7	,	,	,
cord-287670-z6ckhkgg	27	8	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	27	9	acts	act	VBZ
cord-287670-z6ckhkgg	27	10	as	as	IN
cord-287670-z6ckhkgg	27	11	an	an	DT
cord-287670-z6ckhkgg	27	12	oncosuppressor	oncosuppressor	NN
cord-287670-z6ckhkgg	27	13	gene	gene	NN
cord-287670-z6ckhkgg	27	14	in	in	IN
cord-287670-z6ckhkgg	27	15	mice	mouse	NNS
cord-287670-z6ckhkgg	27	16	and	and	CC
cord-287670-z6ckhkgg	27	17	selected	select	VBN
cord-287670-z6ckhkgg	27	18	human	human	JJ
cord-287670-z6ckhkgg	27	19	tumors	tumor	NNS
cord-287670-z6ckhkgg	27	20	.	.	.
cord-287670-z6ckhkgg	28	1	By	by	IN
cord-287670-z6ckhkgg	28	2	interacting	interact	VBG
cord-287670-z6ckhkgg	28	3	with	with	IN
cord-287670-z6ckhkgg	28	4	provisional	provisional	JJ
cord-287670-z6ckhkgg	28	5	matrix	matrix	NN
cord-287670-z6ckhkgg	28	6	components	component	NNS
cord-287670-z6ckhkgg	28	7	,	,	,
cord-287670-z6ckhkgg	28	8	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	28	9	contributes	contribute	VBZ
cord-287670-z6ckhkgg	28	10	to	to	IN
cord-287670-z6ckhkgg	28	11	the	the	DT
cord-287670-z6ckhkgg	28	12	orchestration	orchestration	NN
cord-287670-z6ckhkgg	28	13	of	of	IN
cord-287670-z6ckhkgg	28	14	wound	wound	JJ
cord-287670-z6ckhkgg	28	15	healing	healing	NN
cord-287670-z6ckhkgg	28	16	and	and	CC
cord-287670-z6ckhkgg	28	17	tissue	tissue	NN
cord-287670-z6ckhkgg	28	18	repair	repair	NN
cord-287670-z6ckhkgg	28	19	/	/	SYM
cord-287670-z6ckhkgg	28	20	remodeling	remodeling	NN
cord-287670-z6ckhkgg	28	21	.	.	.
cord-287670-z6ckhkgg	29	1	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	29	2	and	and	CC
cord-287670-z6ckhkgg	29	3	the	the	DT
cord-287670-z6ckhkgg	29	4	related	relate	VBN
cord-287670-z6ckhkgg	29	5	pentraxins	pentraxin	NNS
cord-287670-z6ckhkgg	29	6	Creactive	Creactive	NNP
cord-287670-z6ckhkgg	29	7	protein	protein	NN
cord-287670-z6ckhkgg	29	8	(	(	-LRB-
cord-287670-z6ckhkgg	29	9	CRP	CRP	NNP
cord-287670-z6ckhkgg	29	10	)	)	-RRB-
cord-287670-z6ckhkgg	29	11	and	and	CC
cord-287670-z6ckhkgg	29	12	serum	serum	NN
cord-287670-z6ckhkgg	29	13	amyloid	amyloid	NN
cord-287670-z6ckhkgg	29	14	P	P	NNP
cord-287670-z6ckhkgg	29	15	(	(	-LRB-
cord-287670-z6ckhkgg	29	16	SAP	SAP	NNP
cord-287670-z6ckhkgg	29	17	)	)	-RRB-
cord-287670-z6ckhkgg	29	18	can	can	MD
cord-287670-z6ckhkgg	29	19	exert	exert	VB
cord-287670-z6ckhkgg	29	20	dual	dual	JJ
cord-287670-z6ckhkgg	29	21	roles	role	NNS
cord-287670-z6ckhkgg	29	22	in	in	IN
cord-287670-z6ckhkgg	29	23	inflammation	inflammation	NN
cord-287670-z6ckhkgg	29	24	and	and	CC
cord-287670-z6ckhkgg	29	25	antimicrobial	antimicrobial	JJ
cord-287670-z6ckhkgg	29	26	resistance	resistance	NN
cord-287670-z6ckhkgg	29	27	,	,	,
cord-287670-z6ckhkgg	29	28	by	by	IN
cord-287670-z6ckhkgg	29	29	either	either	CC
cord-287670-z6ckhkgg	29	30	exerting	exert	VBG
cord-287670-z6ckhkgg	29	31	a	a	DT
cord-287670-z6ckhkgg	29	32	protective	protective	JJ
cord-287670-z6ckhkgg	29	33	function	function	NN
cord-287670-z6ckhkgg	29	34	or	or	CC
cord-287670-z6ckhkgg	29	35	amplifying	amplify	VBG
cord-287670-z6ckhkgg	29	36	tissue	tissue	NN
cord-287670-z6ckhkgg	29	37	damage	damage	NN
cord-287670-z6ckhkgg	29	38	.	.	.
cord-287670-z6ckhkgg	30	1	Dissection	dissection	NN
cord-287670-z6ckhkgg	30	2	of	of	IN
cord-287670-z6ckhkgg	30	3	the	the	DT
cord-287670-z6ckhkgg	30	4	yin	yin	NNP
cord-287670-z6ckhkgg	30	5	-	-	HYPH
cord-287670-z6ckhkgg	30	6	yang	yang	NNP
cord-287670-z6ckhkgg	30	7	role	role	NN
cord-287670-z6ckhkgg	30	8	of	of	IN
cord-287670-z6ckhkgg	30	9	pentraxins	pentraxin	NNS
cord-287670-z6ckhkgg	30	10	in	in	IN
cord-287670-z6ckhkgg	30	11	immunopathology	immunopathology	NN
cord-287670-z6ckhkgg	30	12	may	may	MD
cord-287670-z6ckhkgg	30	13	pave	pave	VB
cord-287670-z6ckhkgg	30	14	the	the	DT
cord-287670-z6ckhkgg	30	15	way	way	NN
cord-287670-z6ckhkgg	30	16	towards	towards	IN
cord-287670-z6ckhkgg	30	17	better	well	JJR
cord-287670-z6ckhkgg	30	18	exploitation	exploitation	NN
cord-287670-z6ckhkgg	30	19	of	of	IN
cord-287670-z6ckhkgg	30	20	these	these	DT
cord-287670-z6ckhkgg	30	21	molecules	molecule	NNS
cord-287670-z6ckhkgg	30	22	as	as	IN
cord-287670-z6ckhkgg	30	23	envisaged	envisage	VBN
cord-287670-z6ckhkgg	30	24	disease	disease	NN
cord-287670-z6ckhkgg	30	25	markers	marker	NNS
cord-287670-z6ckhkgg	30	26	and	and	CC
cord-287670-z6ckhkgg	30	27	candidate	candidate	NN
cord-287670-z6ckhkgg	30	28	therapeutic	therapeutic	JJ
cord-287670-z6ckhkgg	30	29	agents	agent	NNS
cord-287670-z6ckhkgg	30	30	.	.	.
cord-287670-z6ckhkgg	31	1	The	the	DT
cord-287670-z6ckhkgg	31	2	rapid	rapid	JJ
cord-287670-z6ckhkgg	31	3	production	production	NN
cord-287670-z6ckhkgg	31	4	of	of	IN
cord-287670-z6ckhkgg	31	5	pentraxins	pentraxin	NNS
cord-287670-z6ckhkgg	31	6	at	at	IN
cord-287670-z6ckhkgg	31	7	the	the	DT
cord-287670-z6ckhkgg	31	8	systemic	systemic	JJ
cord-287670-z6ckhkgg	31	9	level	level	NN
cord-287670-z6ckhkgg	31	10	or	or	CC
cord-287670-z6ckhkgg	31	11	within	within	IN
cord-287670-z6ckhkgg	31	12	tissues	tissue	NNS
cord-287670-z6ckhkgg	31	13	has	have	VBZ
cord-287670-z6ckhkgg	31	14	been	be	VBN
cord-287670-z6ckhkgg	31	15	shown	show	VBN
cord-287670-z6ckhkgg	31	16	to	to	TO
cord-287670-z6ckhkgg	31	17	correlate	correlate	VB
cord-287670-z6ckhkgg	31	18	with	with	IN
cord-287670-z6ckhkgg	31	19	the	the	DT
cord-287670-z6ckhkgg	31	20	severity	severity	NN
cord-287670-z6ckhkgg	31	21	of	of	IN
cord-287670-z6ckhkgg	31	22	various	various	JJ
cord-287670-z6ckhkgg	31	23	clinical	clinical	JJ
cord-287670-z6ckhkgg	31	24	conditions	condition	NNS
cord-287670-z6ckhkgg	31	25	,	,	,
cord-287670-z6ckhkgg	31	26	such	such	JJ
cord-287670-z6ckhkgg	31	27	as	as	IN
cord-287670-z6ckhkgg	31	28	cardiovascular	cardiovascular	JJ
cord-287670-z6ckhkgg	31	29	diseases	disease	NNS
cord-287670-z6ckhkgg	31	30	[	[	-LRB-
cord-287670-z6ckhkgg	31	31	7	7	CD
cord-287670-z6ckhkgg	31	32	]	]	-RRB-
cord-287670-z6ckhkgg	32	1	[	[	-LRB-
cord-287670-z6ckhkgg	32	2	8	8	CD
cord-287670-z6ckhkgg	32	3	]	]	-RRB-
cord-287670-z6ckhkgg	32	4	[	[	-LRB-
cord-287670-z6ckhkgg	32	5	9	9	CD
cord-287670-z6ckhkgg	32	6	]	]	-RRB-
cord-287670-z6ckhkgg	32	7	.	.	.
cord-287670-z6ckhkgg	33	1	This	this	DT
cord-287670-z6ckhkgg	33	2	in	in	IN
cord-287670-z6ckhkgg	33	3	turn	turn	NN
cord-287670-z6ckhkgg	33	4	appears	appear	VBZ
cord-287670-z6ckhkgg	33	5	to	to	TO
cord-287670-z6ckhkgg	33	6	sustain	sustain	VB
cord-287670-z6ckhkgg	33	7	their	-PRON-	PRP$
cord-287670-z6ckhkgg	33	8	high	high	JJ
cord-287670-z6ckhkgg	33	9	levels	level	NNS
cord-287670-z6ckhkgg	33	10	of	of	IN
cord-287670-z6ckhkgg	33	11	expression	expression	NN
cord-287670-z6ckhkgg	33	12	and	and	CC
cord-287670-z6ckhkgg	33	13	consequently	consequently	RB
cord-287670-z6ckhkgg	33	14	has	have	VBZ
cord-287670-z6ckhkgg	33	15	often	often	RB
cord-287670-z6ckhkgg	33	16	raised	raise	VBN
cord-287670-z6ckhkgg	33	17	the	the	DT
cord-287670-z6ckhkgg	33	18	question	question	NN
cord-287670-z6ckhkgg	33	19	of	of	IN
cord-287670-z6ckhkgg	33	20	their	-PRON-	PRP$
cord-287670-z6ckhkgg	33	21	precise	precise	JJ
cord-287670-z6ckhkgg	33	22	role	role	NN
cord-287670-z6ckhkgg	33	23	in	in	IN
cord-287670-z6ckhkgg	33	24	a	a	DT
cord-287670-z6ckhkgg	33	25	given	give	VBN
cord-287670-z6ckhkgg	33	26	disease	disease	NN
cord-287670-z6ckhkgg	33	27	:	:	:
cord-287670-z6ckhkgg	33	28	are	be	VBP
cord-287670-z6ckhkgg	33	29	they	-PRON-	PRP
cord-287670-z6ckhkgg	33	30	simple	simple	JJ
cord-287670-z6ckhkgg	33	31	markers	marker	NNS
cord-287670-z6ckhkgg	33	32	,	,	,
cord-287670-z6ckhkgg	33	33	innocent	innocent	JJ
cord-287670-z6ckhkgg	33	34	bystanders	bystander	NNS
cord-287670-z6ckhkgg	33	35	,	,	,
cord-287670-z6ckhkgg	33	36	or	or	CC
cord-287670-z6ckhkgg	33	37	players	player	NNS
cord-287670-z6ckhkgg	33	38	in	in	IN
cord-287670-z6ckhkgg	33	39	disease	disease	NN
cord-287670-z6ckhkgg	33	40	pathogenesis	pathogenesis	NN
cord-287670-z6ckhkgg	33	41	[	[	-LRB-
cord-287670-z6ckhkgg	33	42	7	7	CD
cord-287670-z6ckhkgg	33	43	]	]	-RRB-
cord-287670-z6ckhkgg	34	1	[	[	-LRB-
cord-287670-z6ckhkgg	34	2	8	8	CD
cord-287670-z6ckhkgg	34	3	]	]	-RRB-
cord-287670-z6ckhkgg	34	4	[	[	-LRB-
cord-287670-z6ckhkgg	34	5	9	9	CD
cord-287670-z6ckhkgg	34	6	]	]	-RRB-
cord-287670-z6ckhkgg	34	7	?	?	.
cord-287670-z6ckhkgg	35	1	In	in	IN
cord-287670-z6ckhkgg	35	2	particular	particular	JJ
cord-287670-z6ckhkgg	35	3	,	,	,
cord-287670-z6ckhkgg	35	4	CRP	CRP	NNP
cord-287670-z6ckhkgg	35	5	is	be	VBZ
cord-287670-z6ckhkgg	35	6	a	a	DT
cord-287670-z6ckhkgg	35	7	widely	widely	RB
cord-287670-z6ckhkgg	35	8	used	use	VBN
cord-287670-z6ckhkgg	35	9	biomarker	biomarker	NN
cord-287670-z6ckhkgg	35	10	of	of	IN
cord-287670-z6ckhkgg	35	11	inflammation	inflammation	NN
cord-287670-z6ckhkgg	35	12	in	in	IN
cord-287670-z6ckhkgg	35	13	humans	human	NNS
cord-287670-z6ckhkgg	35	14	;	;	:
cord-287670-z6ckhkgg	35	15	however	however	RB
cord-287670-z6ckhkgg	35	16	,	,	,
cord-287670-z6ckhkgg	35	17	lack	lack	NN
cord-287670-z6ckhkgg	35	18	of	of	IN
cord-287670-z6ckhkgg	35	19	strict	strict	JJ
cord-287670-z6ckhkgg	35	20	evolutionary	evolutionary	JJ
cord-287670-z6ckhkgg	35	21	conservation	conservation	NN
cord-287670-z6ckhkgg	35	22	between	between	IN
cord-287670-z6ckhkgg	35	23	mouse	mouse	NN
cord-287670-z6ckhkgg	35	24	and	and	CC
cord-287670-z6ckhkgg	35	25	human	human	NN
cord-287670-z6ckhkgg	35	26	has	have	VBZ
cord-287670-z6ckhkgg	35	27	precluded	preclude	VBN
cord-287670-z6ckhkgg	35	28	the	the	DT
cord-287670-z6ckhkgg	35	29	use	use	NN
cord-287670-z6ckhkgg	35	30	of	of	IN
cord-287670-z6ckhkgg	35	31	straightforward	straightforward	JJ
cord-287670-z6ckhkgg	35	32	genetic	genetic	JJ
cord-287670-z6ckhkgg	35	33	approaches	approach	NNS
cord-287670-z6ckhkgg	35	34	to	to	TO
cord-287670-z6ckhkgg	35	35	explore	explore	VB
cord-287670-z6ckhkgg	35	36	its	-PRON-	PRP$
cord-287670-z6ckhkgg	35	37	functions	function	NNS
cord-287670-z6ckhkgg	35	38	in	in	IN
cord-287670-z6ckhkgg	35	39	vivo	vivo	NNP
cord-287670-z6ckhkgg	35	40	[	[	-LRB-
cord-287670-z6ckhkgg	35	41	10	10	CD
cord-287670-z6ckhkgg	35	42	,	,	,
cord-287670-z6ckhkgg	35	43	11	11	CD
cord-287670-z6ckhkgg	35	44	]	]	-RRB-
cord-287670-z6ckhkgg	35	45	.	.	.
cord-287670-z6ckhkgg	36	1	By	by	IN
cord-287670-z6ckhkgg	36	2	contrast	contrast	NN
cord-287670-z6ckhkgg	36	3	,	,	,
cord-287670-z6ckhkgg	36	4	gene	gene	NN
cord-287670-z6ckhkgg	36	5	-	-	HYPH
cord-287670-z6ckhkgg	36	6	targeted	target	VBN
cord-287670-z6ckhkgg	36	7	mice	mouse	NNS
cord-287670-z6ckhkgg	36	8	have	have	VBP
cord-287670-z6ckhkgg	36	9	allowed	allow	VBN
cord-287670-z6ckhkgg	36	10	us	-PRON-	PRP
cord-287670-z6ckhkgg	36	11	to	to	TO
cord-287670-z6ckhkgg	36	12	define	define	VB
cord-287670-z6ckhkgg	36	13	the	the	DT
cord-287670-z6ckhkgg	36	14	role	role	NN
cord-287670-z6ckhkgg	36	15	of	of	IN
cord-287670-z6ckhkgg	36	16	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	36	17	in	in	IN
cord-287670-z6ckhkgg	36	18	innate	innate	JJ
cord-287670-z6ckhkgg	36	19	immunity	immunity	NN
cord-287670-z6ckhkgg	36	20	and	and	CC
cord-287670-z6ckhkgg	36	21	inflammation	inflammation	NN
cord-287670-z6ckhkgg	36	22	as	as	IN
cord-287670-z6ckhkgg	36	23	a	a	DT
cord-287670-z6ckhkgg	36	24	predecessor	predecessor	NN
cord-287670-z6ckhkgg	36	25	to	to	IN
cord-287670-z6ckhkgg	36	26	antibody	antibody	NN
cord-287670-z6ckhkgg	36	27	functions	function	NNS
cord-287670-z6ckhkgg	36	28	and	and	CC
cord-287670-z6ckhkgg	36	29	an	an	DT
cord-287670-z6ckhkgg	36	30	active	active	JJ
cord-287670-z6ckhkgg	36	31	player	player	NN
cord-287670-z6ckhkgg	36	32	in	in	IN
cord-287670-z6ckhkgg	36	33	tissue	tissue	NN
cord-287670-z6ckhkgg	36	34	remodeling	remodel	VBG
cord-287670-z6ckhkgg	36	35	[	[	-LRB-
cord-287670-z6ckhkgg	36	36	5	5	CD
cord-287670-z6ckhkgg	36	37	,	,	,
cord-287670-z6ckhkgg	36	38	[	[	-LRB-
cord-287670-z6ckhkgg	36	39	12	12	CD
cord-287670-z6ckhkgg	36	40	]	]	-RRB-
cord-287670-z6ckhkgg	36	41	[	[	-LRB-
cord-287670-z6ckhkgg	36	42	13	13	CD
cord-287670-z6ckhkgg	36	43	]	]	-RRB-
cord-287670-z6ckhkgg	36	44	[	[	-LRB-
cord-287670-z6ckhkgg	36	45	14	14	CD
cord-287670-z6ckhkgg	36	46	]	]	-RRB-
cord-287670-z6ckhkgg	36	47	.	.	.
cord-287670-z6ckhkgg	37	1	Even	even	RB
cord-287670-z6ckhkgg	37	2	if	if	IN
cord-287670-z6ckhkgg	37	3	most	most	JJS
cord-287670-z6ckhkgg	37	4	animal	animal	NN
cord-287670-z6ckhkgg	37	5	studies	study	NNS
cord-287670-z6ckhkgg	37	6	on	on	IN
cord-287670-z6ckhkgg	37	7	the	the	DT
cord-287670-z6ckhkgg	37	8	long	long	JJ
cord-287670-z6ckhkgg	37	9	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	37	10	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	37	11	are	be	VBP
cord-287670-z6ckhkgg	37	12	supported	support	VBN
cord-287670-z6ckhkgg	37	13	by	by	IN
cord-287670-z6ckhkgg	37	14	human	human	JJ
cord-287670-z6ckhkgg	37	15	genetic	genetic	JJ
cord-287670-z6ckhkgg	37	16	findings	finding	NNS
cord-287670-z6ckhkgg	37	17	suggesting	suggest	VBG
cord-287670-z6ckhkgg	37	18	that	that	IN
cord-287670-z6ckhkgg	37	19	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	37	20	is	be	VBZ
cord-287670-z6ckhkgg	37	21	important	important	JJ
cord-287670-z6ckhkgg	37	22	in	in	IN
cord-287670-z6ckhkgg	37	23	conferring	confer	VBG
cord-287670-z6ckhkgg	37	24	host	host	NN
cord-287670-z6ckhkgg	37	25	resistance	resistance	NN
cord-287670-z6ckhkgg	37	26	to	to	IN
cord-287670-z6ckhkgg	37	27	infection	infection	NN
cord-287670-z6ckhkgg	37	28	[	[	-LRB-
cord-287670-z6ckhkgg	37	29	15	15	CD
cord-287670-z6ckhkgg	37	30	,	,	,
cord-287670-z6ckhkgg	37	31	16	16	CD
cord-287670-z6ckhkgg	37	32	]	]	-RRB-
cord-287670-z6ckhkgg	37	33	,	,	,
cord-287670-z6ckhkgg	37	34	a	a	DT
cord-287670-z6ckhkgg	37	35	prevalent	prevalent	JJ
cord-287670-z6ckhkgg	37	36	concept	concept	NN
cord-287670-z6ckhkgg	37	37	has	have	VBZ
cord-287670-z6ckhkgg	37	38	surfaced	surface	VBN
cord-287670-z6ckhkgg	37	39	:	:	:
cord-287670-z6ckhkgg	37	40	depending	depend	VBG
cord-287670-z6ckhkgg	37	41	on	on	IN
cord-287670-z6ckhkgg	37	42	the	the	DT
cord-287670-z6ckhkgg	37	43	disease	disease	NN
cord-287670-z6ckhkgg	37	44	context	context	NN
cord-287670-z6ckhkgg	37	45	,	,	,
cord-287670-z6ckhkgg	37	46	the	the	DT
cord-287670-z6ckhkgg	37	47	cellular	cellular	JJ
cord-287670-z6ckhkgg	37	48	source	source	NN
cord-287670-z6ckhkgg	37	49	,	,	,
cord-287670-z6ckhkgg	37	50	or	or	CC
cord-287670-z6ckhkgg	37	51	the	the	DT
cord-287670-z6ckhkgg	37	52	levels	level	NNS
cord-287670-z6ckhkgg	37	53	of	of	IN
cord-287670-z6ckhkgg	37	54	protein	protein	NN
cord-287670-z6ckhkgg	37	55	released	release	VBN
cord-287670-z6ckhkgg	37	56	,	,	,
cord-287670-z6ckhkgg	37	57	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	37	58	may	may	MD
cord-287670-z6ckhkgg	37	59	contribute	contribute	VB
cord-287670-z6ckhkgg	37	60	to	to	IN
cord-287670-z6ckhkgg	37	61	disease	disease	NN
cord-287670-z6ckhkgg	37	62	pathogenesis	pathogenesis	NN
cord-287670-z6ckhkgg	37	63	[	[	-LRB-
cord-287670-z6ckhkgg	37	64	12	12	CD
cord-287670-z6ckhkgg	37	65	,	,	,
cord-287670-z6ckhkgg	37	66	[	[	-LRB-
cord-287670-z6ckhkgg	37	67	17	17	CD
cord-287670-z6ckhkgg	37	68	]	]	-RRB-
cord-287670-z6ckhkgg	37	69	[	[	-LRB-
cord-287670-z6ckhkgg	37	70	18	18	CD
cord-287670-z6ckhkgg	37	71	]	]	-RRB-
cord-287670-z6ckhkgg	37	72	[	[	-LRB-
cord-287670-z6ckhkgg	37	73	19	19	CD
cord-287670-z6ckhkgg	37	74	]	]	-RRB-
cord-287670-z6ckhkgg	37	75	.	.	.
cord-287670-z6ckhkgg	38	1	Consequently	consequently	RB
cord-287670-z6ckhkgg	38	2	,	,	,
cord-287670-z6ckhkgg	38	3	this	this	DT
cord-287670-z6ckhkgg	38	4	review	review	NN
cord-287670-z6ckhkgg	38	5	focuses	focus	VBZ
cord-287670-z6ckhkgg	38	6	on	on	IN
cord-287670-z6ckhkgg	38	7	the	the	DT
cord-287670-z6ckhkgg	38	8	multifaceted	multifaceted	JJ
cord-287670-z6ckhkgg	38	9	and	and	CC
cord-287670-z6ckhkgg	38	10	yin	yin	NNP
cord-287670-z6ckhkgg	38	11	-	-	HYPH
cord-287670-z6ckhkgg	38	12	yang	yang	NNP
cord-287670-z6ckhkgg	38	13	role	role	NN
cord-287670-z6ckhkgg	38	14	of	of	IN
cord-287670-z6ckhkgg	38	15	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	38	16	in	in	IN
cord-287670-z6ckhkgg	38	17	humoral	humoral	JJ
cord-287670-z6ckhkgg	38	18	innate	innate	JJ
cord-287670-z6ckhkgg	38	19	immunity	immunity	NN
cord-287670-z6ckhkgg	38	20	,	,	,
cord-287670-z6ckhkgg	38	21	microbial	microbial	JJ
cord-287670-z6ckhkgg	38	22	defense	defense	NN
cord-287670-z6ckhkgg	38	23	,	,	,
cord-287670-z6ckhkgg	38	24	and	and	CC
cord-287670-z6ckhkgg	38	25	regulation	regulation	NN
cord-287670-z6ckhkgg	38	26	of	of	IN
cord-287670-z6ckhkgg	38	27	inflammation	inflammation	NN
cord-287670-z6ckhkgg	38	28	as	as	RB
cord-287670-z6ckhkgg	38	29	well	well	RB
cord-287670-z6ckhkgg	38	30	as	as	IN
cord-287670-z6ckhkgg	38	31	in	in	IN
cord-287670-z6ckhkgg	38	32	tissue	tissue	NN
cord-287670-z6ckhkgg	38	33	remodeling	remodeling	NN
cord-287670-z6ckhkgg	38	34	and	and	CC
cord-287670-z6ckhkgg	38	35	repair	repair	NN
cord-287670-z6ckhkgg	38	36	.	.	.
cord-287670-z6ckhkgg	39	1	This	this	DT
cord-287670-z6ckhkgg	39	2	concept	concept	NN
cord-287670-z6ckhkgg	39	3	is	be	VBZ
cord-287670-z6ckhkgg	39	4	presented	present	VBN
cord-287670-z6ckhkgg	39	5	at	at	IN
cord-287670-z6ckhkgg	39	6	an	an	DT
cord-287670-z6ckhkgg	39	7	exciting	exciting	JJ
cord-287670-z6ckhkgg	39	8	moment	moment	NN
cord-287670-z6ckhkgg	39	9	,	,	,
cord-287670-z6ckhkgg	39	10	when	when	WRB
cord-287670-z6ckhkgg	39	11	key	key	JJ
cord-287670-z6ckhkgg	39	12	players	player	NNS
cord-287670-z6ckhkgg	39	13	in	in	IN
cord-287670-z6ckhkgg	39	14	innate	innate	JJ
cord-287670-z6ckhkgg	39	15	immunity	immunity	NN
cord-287670-z6ckhkgg	39	16	,	,	,
cord-287670-z6ckhkgg	39	17	the	the	DT
cord-287670-z6ckhkgg	39	18	pentraxins	pentraxin	NNS
cord-287670-z6ckhkgg	39	19	,	,	,
cord-287670-z6ckhkgg	39	20	have	have	VBP
cord-287670-z6ckhkgg	39	21	emerged	emerge	VBN
cord-287670-z6ckhkgg	39	22	as	as	IN
cord-287670-z6ckhkgg	39	23	being	be	VBG
cord-287670-z6ckhkgg	39	24	capable	capable	JJ
cord-287670-z6ckhkgg	39	25	of	of	IN
cord-287670-z6ckhkgg	39	26	exerting	exert	VBG
cord-287670-z6ckhkgg	39	27	potential	potential	JJ
cord-287670-z6ckhkgg	39	28	contradictory	contradictory	JJ
cord-287670-z6ckhkgg	39	29	roles	role	NNS
cord-287670-z6ckhkgg	39	30	in	in	IN
cord-287670-z6ckhkgg	39	31	health	health	NN
cord-287670-z6ckhkgg	39	32	and	and	CC
cord-287670-z6ckhkgg	39	33	disease	disease	NN
cord-287670-z6ckhkgg	39	34	.	.	.
cord-287670-z6ckhkgg	40	1	This	this	DT
cord-287670-z6ckhkgg	40	2	is	be	VBZ
cord-287670-z6ckhkgg	40	3	an	an	DT
cord-287670-z6ckhkgg	40	4	opportune	opportune	JJ
cord-287670-z6ckhkgg	40	5	time	time	NN
cord-287670-z6ckhkgg	40	6	to	to	TO
cord-287670-z6ckhkgg	40	7	begin	begin	VB
cord-287670-z6ckhkgg	40	8	making	make	VBG
cord-287670-z6ckhkgg	40	9	a	a	DT
cord-287670-z6ckhkgg	40	10	greater	great	JJR
cord-287670-z6ckhkgg	40	11	effort	effort	NN
cord-287670-z6ckhkgg	40	12	to	to	TO
cord-287670-z6ckhkgg	40	13	elucidate	elucidate	VB
cord-287670-z6ckhkgg	40	14	the	the	DT
cord-287670-z6ckhkgg	40	15	exact	exact	JJ
cord-287670-z6ckhkgg	40	16	roles	role	NNS
cord-287670-z6ckhkgg	40	17	of	of	IN
cord-287670-z6ckhkgg	40	18	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	40	19	in	in	IN
cord-287670-z6ckhkgg	40	20	disease	disease	NN
cord-287670-z6ckhkgg	40	21	pathogenesis	pathogenesis	NN
cord-287670-z6ckhkgg	40	22	and	and	CC
cord-287670-z6ckhkgg	40	23	to	to	TO
cord-287670-z6ckhkgg	40	24	better	better	RB
cord-287670-z6ckhkgg	40	25	dissect	dissect	VB
cord-287670-z6ckhkgg	40	26	its	-PRON-	PRP$
cord-287670-z6ckhkgg	40	27	precise	precise	JJ
cord-287670-z6ckhkgg	40	28	mechanisms	mechanism	NNS
cord-287670-z6ckhkgg	40	29	of	of	IN
cord-287670-z6ckhkgg	40	30	action	action	NN
cord-287670-z6ckhkgg	40	31	in	in	IN
cord-287670-z6ckhkgg	40	32	a	a	DT
cord-287670-z6ckhkgg	40	33	context	context	NN
cord-287670-z6ckhkgg	40	34	-	-	HYPH
cord-287670-z6ckhkgg	40	35	specific	specific	JJ
cord-287670-z6ckhkgg	40	36	manner	manner	NN
cord-287670-z6ckhkgg	40	37	.	.	.
cord-287670-z6ckhkgg	41	1	Pentraxins	pentraxin	NNS
cord-287670-z6ckhkgg	41	2	are	be	VBP
cord-287670-z6ckhkgg	41	3	conserved	conserve	VBN
cord-287670-z6ckhkgg	41	4	multimeric	multimeric	JJ
cord-287670-z6ckhkgg	41	5	proteins	protein	NNS
cord-287670-z6ckhkgg	41	6	characterized	characterize	VBN
cord-287670-z6ckhkgg	41	7	by	by	IN
cord-287670-z6ckhkgg	41	8	the	the	DT
cord-287670-z6ckhkgg	41	9	presence	presence	NN
cord-287670-z6ckhkgg	41	10	of	of	IN
cord-287670-z6ckhkgg	41	11	a	a	DT
cord-287670-z6ckhkgg	41	12	conserved	conserved	JJ
cord-287670-z6ckhkgg	41	13	eight	eight	CD
cord-287670-z6ckhkgg	41	14	-	-	HYPH
cord-287670-z6ckhkgg	41	15	amino	amino	NN
cord-287670-z6ckhkgg	41	16	-	-	HYPH
cord-287670-z6ckhkgg	41	17	acid	acid	NN
cord-287670-z6ckhkgg	41	18	sequence	sequence	NN
cord-287670-z6ckhkgg	41	19	,	,	,
cord-287670-z6ckhkgg	41	20	the	the	DT
cord-287670-z6ckhkgg	41	21	'	'	``
cord-287670-z6ckhkgg	41	22	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	41	23	domain	domain	NN
cord-287670-z6ckhkgg	41	24	'	'	''
cord-287670-z6ckhkgg	41	25	,	,	,
cord-287670-z6ckhkgg	41	26	in	in	IN
cord-287670-z6ckhkgg	41	27	their	-PRON-	PRP$
cord-287670-z6ckhkgg	41	28	carboxy	carboxy	JJ
cord-287670-z6ckhkgg	41	29	terminus	terminus	NN
cord-287670-z6ckhkgg	41	30	[	[	-LRB-
cord-287670-z6ckhkgg	41	31	4	4	CD
cord-287670-z6ckhkgg	41	32	]	]	-RRB-
cord-287670-z6ckhkgg	41	33	.	.	.
cord-287670-z6ckhkgg	42	1	Based	base	VBN
cord-287670-z6ckhkgg	42	2	on	on	IN
cord-287670-z6ckhkgg	42	3	the	the	DT
cord-287670-z6ckhkgg	42	4	primary	primary	JJ
cord-287670-z6ckhkgg	42	5	structure	structure	NN
cord-287670-z6ckhkgg	42	6	of	of	IN
cord-287670-z6ckhkgg	42	7	the	the	DT
cord-287670-z6ckhkgg	42	8	protomer	protomer	NNP
cord-287670-z6ckhkgg	42	9	,	,	,
cord-287670-z6ckhkgg	42	10	pentraxins	pentraxin	NNS
cord-287670-z6ckhkgg	42	11	have	have	VBP
cord-287670-z6ckhkgg	42	12	been	be	VBN
cord-287670-z6ckhkgg	42	13	divided	divide	VBN
cord-287670-z6ckhkgg	42	14	into	into	IN
cord-287670-z6ckhkgg	42	15	short	short	JJ
cord-287670-z6ckhkgg	42	16	pentraxins	pentraxin	NNS
cord-287670-z6ckhkgg	42	17	,	,	,
cord-287670-z6ckhkgg	42	18	including	include	VBG
cord-287670-z6ckhkgg	42	19	CRP	CRP	NNP
cord-287670-z6ckhkgg	42	20	and	and	CC
cord-287670-z6ckhkgg	42	21	SAP	SAP	NNP
cord-287670-z6ckhkgg	42	22	,	,	,
cord-287670-z6ckhkgg	42	23	and	and	CC
cord-287670-z6ckhkgg	42	24	long	long	JJ
cord-287670-z6ckhkgg	42	25	pentraxins	pentraxin	NNS
cord-287670-z6ckhkgg	42	26	,	,	,
cord-287670-z6ckhkgg	42	27	such	such	JJ
cord-287670-z6ckhkgg	42	28	as	as	IN
cord-287670-z6ckhkgg	42	29	the	the	DT
cord-287670-z6ckhkgg	42	30	prototype	prototype	NN
cord-287670-z6ckhkgg	42	31	long	long	RB
cord-287670-z6ckhkgg	42	32	pentraxin	pentraxin	NNP
cord-287670-z6ckhkgg	42	33	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	42	34	[	[	-LRB-
cord-287670-z6ckhkgg	42	35	4	4	CD
cord-287670-z6ckhkgg	42	36	]	]	-RRB-
cord-287670-z6ckhkgg	42	37	.	.	.
cord-287670-z6ckhkgg	43	1	CRP	CRP	NNP
cord-287670-z6ckhkgg	43	2	and	and	CC
cord-287670-z6ckhkgg	43	3	SAP	SAP	NNP
cord-287670-z6ckhkgg	43	4	are	be	VBP
cord-287670-z6ckhkgg	43	5	approximately	approximately	RB
cord-287670-z6ckhkgg	43	6	25-kDa	25-kda	CD
cord-287670-z6ckhkgg	43	7	proteins	protein	NNS
cord-287670-z6ckhkgg	43	8	organized	organize	VBN
cord-287670-z6ckhkgg	43	9	in	in	IN
cord-287670-z6ckhkgg	43	10	five	five	CD
cord-287670-z6ckhkgg	43	11	identical	identical	JJ
cord-287670-z6ckhkgg	43	12	subunits	subunit	NNS
cord-287670-z6ckhkgg	43	13	arranged	arrange	VBN
cord-287670-z6ckhkgg	43	14	with	with	IN
cord-287670-z6ckhkgg	43	15	pentameric	pentameric	NN
cord-287670-z6ckhkgg	43	16	radial	radial	JJ
cord-287670-z6ckhkgg	43	17	symmetry	symmetry	NN
cord-287670-z6ckhkgg	43	18	[	[	-LRB-
cord-287670-z6ckhkgg	43	19	3	3	CD
cord-287670-z6ckhkgg	43	20	,	,	,
cord-287670-z6ckhkgg	43	21	4	4	CD
cord-287670-z6ckhkgg	43	22	]	]	-RRB-
cord-287670-z6ckhkgg	43	23	.	.	.
cord-287670-z6ckhkgg	44	1	CRP	CRP	NNP
cord-287670-z6ckhkgg	44	2	and	and	CC
cord-287670-z6ckhkgg	44	3	SAP	SAP	NNP
cord-287670-z6ckhkgg	44	4	are	be	VBP
cord-287670-z6ckhkgg	44	5	the	the	DT
cord-287670-z6ckhkgg	44	6	main	main	JJ
cord-287670-z6ckhkgg	44	7	acute	acute	JJ
cord-287670-z6ckhkgg	44	8	phase	phase	NN
cord-287670-z6ckhkgg	44	9	proteins	protein	NNS
cord-287670-z6ckhkgg	44	10	produced	produce	VBN
cord-287670-z6ckhkgg	44	11	by	by	IN
cord-287670-z6ckhkgg	44	12	human	human	JJ
cord-287670-z6ckhkgg	44	13	and	and	CC
cord-287670-z6ckhkgg	44	14	murine	murine	JJ
cord-287670-z6ckhkgg	44	15	liver	liver	NN
cord-287670-z6ckhkgg	44	16	,	,	,
cord-287670-z6ckhkgg	44	17	respectively	respectively	RB
cord-287670-z6ckhkgg	44	18	[	[	-LRB-
cord-287670-z6ckhkgg	44	19	3	3	CD
cord-287670-z6ckhkgg	44	20	]	]	-RRB-
cord-287670-z6ckhkgg	44	21	.	.	.
cord-287670-z6ckhkgg	45	1	They	-PRON-	PRP
cord-287670-z6ckhkgg	45	2	act	act	VBP
cord-287670-z6ckhkgg	45	3	as	as	IN
cord-287670-z6ckhkgg	45	4	players	player	NNS
cord-287670-z6ckhkgg	45	5	in	in	IN
cord-287670-z6ckhkgg	45	6	the	the	DT
cord-287670-z6ckhkgg	45	7	innate	innate	JJ
cord-287670-z6ckhkgg	45	8	immune	immune	JJ
cord-287670-z6ckhkgg	45	9	response	response	NN
cord-287670-z6ckhkgg	45	10	by	by	IN
cord-287670-z6ckhkgg	45	11	regulating	regulate	VBG
cord-287670-z6ckhkgg	45	12	the	the	DT
cord-287670-z6ckhkgg	45	13	complement	complement	NN
cord-287670-z6ckhkgg	45	14	system	system	NN
cord-287670-z6ckhkgg	45	15	,	,	,
cord-287670-z6ckhkgg	45	16	recognizing	recognize	VBG
cord-287670-z6ckhkgg	45	17	pathogens	pathogen	NNS
cord-287670-z6ckhkgg	45	18	,	,	,
cord-287670-z6ckhkgg	45	19	and	and	CC
cord-287670-z6ckhkgg	45	20	interacting	interact	VBG
cord-287670-z6ckhkgg	45	21	with	with	IN
cord-287670-z6ckhkgg	45	22	Fcg	Fcg	NNP
cord-287670-z6ckhkgg	45	23	receptors	receptor	NNS
cord-287670-z6ckhkgg	45	24	(	(	-LRB-
cord-287670-z6ckhkgg	45	25	FcgRs	FcgRs	NNP
cord-287670-z6ckhkgg	45	26	)	)	-RRB-
cord-287670-z6ckhkgg	45	27	,	,	,
cord-287670-z6ckhkgg	45	28	thus	thus	RB
cord-287670-z6ckhkgg	45	29	favoring	favor	VBG
cord-287670-z6ckhkgg	45	30	cytokine	cytokine	JJ
cord-287670-z6ckhkgg	45	31	secretion	secretion	NN
cord-287670-z6ckhkgg	45	32	and	and	CC
cord-287670-z6ckhkgg	45	33	phagocytosis	phagocytosis	NN
cord-287670-z6ckhkgg	45	34	of	of	IN
cord-287670-z6ckhkgg	45	35	microorganisms	microorganism	NNS
cord-287670-z6ckhkgg	45	36	by	by	IN
cord-287670-z6ckhkgg	45	37	immune	immune	JJ
cord-287670-z6ckhkgg	45	38	cells	cell	NNS
cord-287670-z6ckhkgg	45	39	[	[	-LRB-
cord-287670-z6ckhkgg	45	40	20	20	CD
cord-287670-z6ckhkgg	45	41	]	]	-RRB-
cord-287670-z6ckhkgg	45	42	.	.	.
cord-287670-z6ckhkgg	46	1	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	46	2	was	be	VBD
cord-287670-z6ckhkgg	46	3	the	the	DT
cord-287670-z6ckhkgg	46	4	first	first	JJ
cord-287670-z6ckhkgg	46	5	long	long	JJ
cord-287670-z6ckhkgg	46	6	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	46	7	identified	identify	VBD
cord-287670-z6ckhkgg	46	8	[	[	-LRB-
cord-287670-z6ckhkgg	46	9	4	4	CD
cord-287670-z6ckhkgg	46	10	]	]	-RRB-
cord-287670-z6ckhkgg	46	11	,	,	,
cord-287670-z6ckhkgg	46	12	followed	follow	VBN
cord-287670-z6ckhkgg	46	13	by	by	IN
cord-287670-z6ckhkgg	46	14	other	other	JJ
cord-287670-z6ckhkgg	46	15	long	long	JJ
cord-287670-z6ckhkgg	46	16	pentraxins	pentraxin	NNS
cord-287670-z6ckhkgg	46	17	including	include	VBG
cord-287670-z6ckhkgg	46	18	guinea	guinea	NN
cord-287670-z6ckhkgg	46	19	pig	pig	NN
cord-287670-z6ckhkgg	46	20	apexin	apexin	NNP
cord-287670-z6ckhkgg	46	21	,	,	,
cord-287670-z6ckhkgg	46	22	neuronal	neuronal	JJ
cord-287670-z6ckhkgg	46	23	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	46	24	(	(	-LRB-
cord-287670-z6ckhkgg	46	25	NP	NP	NNP
cord-287670-z6ckhkgg	46	26	)	)	-RRB-
cord-287670-z6ckhkgg	46	27	1	1	CD
cord-287670-z6ckhkgg	46	28	,	,	,
cord-287670-z6ckhkgg	46	29	NP2	np2	JJ
cord-287670-z6ckhkgg	46	30	,	,	,
cord-287670-z6ckhkgg	46	31	neuronal	neuronal	JJ
cord-287670-z6ckhkgg	46	32	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	46	33	receptor	receptor	NN
cord-287670-z6ckhkgg	46	34	(	(	-LRB-
cord-287670-z6ckhkgg	46	35	NPR	NPR	NNP
cord-287670-z6ckhkgg	46	36	)	)	-RRB-
cord-287670-z6ckhkgg	46	37	,	,	,
cord-287670-z6ckhkgg	46	38	and	and	CC
cord-287670-z6ckhkgg	46	39	PTX4	PTX4	NNP
cord-287670-z6ckhkgg	46	40	[	[	-LRB-
cord-287670-z6ckhkgg	46	41	21	21	CD
cord-287670-z6ckhkgg	46	42	]	]	-RRB-
cord-287670-z6ckhkgg	46	43	.	.	.
cord-287670-z6ckhkgg	47	1	The	the	DT
cord-287670-z6ckhkgg	47	2	gene	gene	NN
cord-287670-z6ckhkgg	47	3	encoding	encode	VBG
cord-287670-z6ckhkgg	47	4	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	47	5	is	be	VBZ
cord-287670-z6ckhkgg	47	6	localized	localize	VBN
cord-287670-z6ckhkgg	47	7	to	to	TO
cord-287670-z6ckhkgg	47	8	chromosome	chromosome	NN
cord-287670-z6ckhkgg	47	9	3	3	CD
cord-287670-z6ckhkgg	47	10	in	in	IN
cord-287670-z6ckhkgg	47	11	humans	human	NNS
cord-287670-z6ckhkgg	47	12	and	and	CC
cord-287670-z6ckhkgg	47	13	mice	mouse	NNS
cord-287670-z6ckhkgg	47	14	and	and	CC
cord-287670-z6ckhkgg	47	15	comprises	comprise	VBZ
cord-287670-z6ckhkgg	47	16	three	three	CD
cord-287670-z6ckhkgg	47	17	exons	exon	NNS
cord-287670-z6ckhkgg	47	18	encoding	encode	VBG
cord-287670-z6ckhkgg	47	19	the	the	DT
cord-287670-z6ckhkgg	47	20	leader	leader	NN
cord-287670-z6ckhkgg	47	21	signal	signal	NN
cord-287670-z6ckhkgg	47	22	peptide	peptide	NN
cord-287670-z6ckhkgg	47	23	,	,	,
cord-287670-z6ckhkgg	47	24	the	the	DT
cord-287670-z6ckhkgg	47	25	N	n	CD
cord-287670-z6ckhkgg	47	26	-	-	HYPH
cord-287670-z6ckhkgg	47	27	terminal	terminal	NN
cord-287670-z6ckhkgg	47	28	domain	domain	NN
cord-287670-z6ckhkgg	47	29	,	,	,
cord-287670-z6ckhkgg	47	30	and	and	CC
cord-287670-z6ckhkgg	47	31	the	the	DT
cord-287670-z6ckhkgg	47	32	C	C	NNP
cord-287670-z6ckhkgg	47	33	-	-	HYPH
cord-287670-z6ckhkgg	47	34	terminal	terminal	NN
cord-287670-z6ckhkgg	47	35	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	47	36	domain	domain	NN
cord-287670-z6ckhkgg	47	37	[	[	-LRB-
cord-287670-z6ckhkgg	47	38	4	4	CD
cord-287670-z6ckhkgg	47	39	]	]	-RRB-
cord-287670-z6ckhkgg	47	40	.	.	.
cord-287670-z6ckhkgg	48	1	The	the	DT
cord-287670-z6ckhkgg	48	2	expression	expression	NN
cord-287670-z6ckhkgg	48	3	of	of	IN
cord-287670-z6ckhkgg	48	4	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	48	5	is	be	VBZ
cord-287670-z6ckhkgg	48	6	mainly	mainly	RB
cord-287670-z6ckhkgg	48	7	induced	induce	VBN
cord-287670-z6ckhkgg	48	8	by	by	IN
cord-287670-z6ckhkgg	48	9	inflammatory	inflammatory	JJ
cord-287670-z6ckhkgg	48	10	stimuli	stimulus	NNS
cord-287670-z6ckhkgg	48	11	such	such	JJ
cord-287670-z6ckhkgg	48	12	as	as	IN
cord-287670-z6ckhkgg	48	13	inflammatory	inflammatory	JJ
cord-287670-z6ckhkgg	48	14	cytokines	cytokine	NNS
cord-287670-z6ckhkgg	48	15	[	[	-LRB-
cord-287670-z6ckhkgg	48	16	tumor	tumor	NN
cord-287670-z6ckhkgg	48	17	necrosis	necrosis	NN
cord-287670-z6ckhkgg	48	18	factor	factor	NN
cord-287670-z6ckhkgg	48	19	alpha	alpha	NN
cord-287670-z6ckhkgg	48	20	(	(	-LRB-
cord-287670-z6ckhkgg	48	21	TNF/	TNF/	NNP
cord-287670-z6ckhkgg	48	22	)	)	-RRB-
cord-287670-z6ckhkgg	48	23	and	and	CC
cord-287670-z6ckhkgg	48	24	IL-1b	IL-1b	NNP
cord-287670-z6ckhkgg	48	25	]	]	-RRB-
cord-287670-z6ckhkgg	48	26	and	and	CC
cord-287670-z6ckhkgg	48	27	damage	damage	NN
cord-287670-z6ckhkgg	48	28	-	-	HYPH
cord-287670-z6ckhkgg	48	29	associated	associate	VBN
cord-287670-z6ckhkgg	48	30	molecular	molecular	JJ
cord-287670-z6ckhkgg	48	31	patterns	pattern	NNS
cord-287670-z6ckhkgg	48	32	(	(	-LRB-
cord-287670-z6ckhkgg	48	33	DAMPs	damp	NNS
cord-287670-z6ckhkgg	48	34	)	)	-RRB-
cord-287670-z6ckhkgg	48	35	or	or	CC
cord-287670-z6ckhkgg	48	36	microbial	microbial	JJ
cord-287670-z6ckhkgg	48	37	moieties	moiety	NNS
cord-287670-z6ckhkgg	48	38	.	.	.
cord-287670-z6ckhkgg	49	1	In	in	IN
cord-287670-z6ckhkgg	49	2	particular	particular	JJ
cord-287670-z6ckhkgg	49	3	,	,	,
cord-287670-z6ckhkgg	49	4	IL-1	IL-1	NNP
cord-287670-z6ckhkgg	49	5	is	be	VBZ
cord-287670-z6ckhkgg	49	6	a	a	DT
cord-287670-z6ckhkgg	49	7	major	major	JJ
cord-287670-z6ckhkgg	49	8	inducer	inducer	NN
cord-287670-z6ckhkgg	49	9	of	of	IN
cord-287670-z6ckhkgg	49	10	local	local	JJ
cord-287670-z6ckhkgg	49	11	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	49	12	production	production	NN
cord-287670-z6ckhkgg	49	13	in	in	IN
cord-287670-z6ckhkgg	49	14	sterile	sterile	JJ
cord-287670-z6ckhkgg	49	15	tissue	tissue	NN
cord-287670-z6ckhkgg	49	16	damage	damage	NN
cord-287670-z6ckhkgg	49	17	,	,	,
cord-287670-z6ckhkgg	49	18	such	such	JJ
cord-287670-z6ckhkgg	49	19	as	as	IN
cord-287670-z6ckhkgg	49	20	in	in	IN
cord-287670-z6ckhkgg	49	21	mouse	mouse	NN
cord-287670-z6ckhkgg	49	22	models	model	NNS
cord-287670-z6ckhkgg	49	23	of	of	IN
cord-287670-z6ckhkgg	49	24	acute	acute	JJ
cord-287670-z6ckhkgg	49	25	myocardial	myocardial	JJ
cord-287670-z6ckhkgg	49	26	infarction	infarction	NN
cord-287670-z6ckhkgg	49	27	and	and	CC
cord-287670-z6ckhkgg	49	28	in	in	IN
cord-287670-z6ckhkgg	49	29	3-methylcholanthrene	3-methylcholanthrene	CD
cord-287670-z6ckhkgg	49	30	(	(	-LRB-
cord-287670-z6ckhkgg	49	31	3-MCA)-induced	3-mca)-induced	CD
cord-287670-z6ckhkgg	49	32	carcinogenesis	carcinogenesis	NN
cord-287670-z6ckhkgg	49	33	[	[	-LRB-
cord-287670-z6ckhkgg	49	34	12	12	CD
cord-287670-z6ckhkgg	49	35	,	,	,
cord-287670-z6ckhkgg	49	36	22	22	CD
cord-287670-z6ckhkgg	49	37	]	]	-RRB-
cord-287670-z6ckhkgg	49	38	.	.	.
cord-287670-z6ckhkgg	50	1	In	in	IN
cord-287670-z6ckhkgg	50	2	skin	skin	NN
cord-287670-z6ckhkgg	50	3	-	-	HYPH
cord-287670-z6ckhkgg	50	4	wound	wound	NN
cord-287670-z6ckhkgg	50	5	healing	healing	NN
cord-287670-z6ckhkgg	50	6	,	,	,
cord-287670-z6ckhkgg	50	7	TLR	TLR	NNP
cord-287670-z6ckhkgg	50	8	sensing	sensing	NN
cord-287670-z6ckhkgg	50	9	and	and	CC
cord-287670-z6ckhkgg	50	10	IL-1	IL-1	NNP
cord-287670-z6ckhkgg	50	11	amplification	amplification	NN
cord-287670-z6ckhkgg	50	12	are	be	VBP
cord-287670-z6ckhkgg	50	13	involved	involve	VBN
cord-287670-z6ckhkgg	50	14	in	in	IN
cord-287670-z6ckhkgg	50	15	the	the	DT
cord-287670-z6ckhkgg	50	16	expression	expression	NN
cord-287670-z6ckhkgg	50	17	and	and	CC
cord-287670-z6ckhkgg	50	18	production	production	NN
cord-287670-z6ckhkgg	50	19	of	of	IN
cord-287670-z6ckhkgg	50	20	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	50	21	[	[	-LRB-
cord-287670-z6ckhkgg	50	22	5	5	CD
cord-287670-z6ckhkgg	50	23	]	]	-RRB-
cord-287670-z6ckhkgg	50	24	.	.	.
cord-287670-z6ckhkgg	51	1	In	in	IN
cord-287670-z6ckhkgg	51	2	urinary	urinary	JJ
cord-287670-z6ckhkgg	51	3	tract	tract	NN
cord-287670-z6ckhkgg	51	4	infections	infection	NNS
cord-287670-z6ckhkgg	51	5	(	(	-LRB-
cord-287670-z6ckhkgg	51	6	UTIs	uti	NNS
cord-287670-z6ckhkgg	51	7	)	)	-RRB-
cord-287670-z6ckhkgg	51	8	mediated	mediate	VBN
cord-287670-z6ckhkgg	51	9	by	by	IN
cord-287670-z6ckhkgg	51	10	uropathogenic	uropathogenic	JJ
cord-287670-z6ckhkgg	51	11	Escherichia	Escherichia	NNP
cord-287670-z6ckhkgg	51	12	coli	coli	NNS
cord-287670-z6ckhkgg	51	13	(	(	-LRB-
cord-287670-z6ckhkgg	51	14	UPEC	UPEC	NNP
cord-287670-z6ckhkgg	51	15	)	)	-RRB-
cord-287670-z6ckhkgg	51	16	,	,	.
cord-287670-z6ckhkgg	52	1	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	52	2	production	production	NN
cord-287670-z6ckhkgg	52	3	by	by	IN
cord-287670-z6ckhkgg	52	4	human	human	JJ
cord-287670-z6ckhkgg	52	5	and	and	CC
cord-287670-z6ckhkgg	52	6	murine	murine	JJ
cord-287670-z6ckhkgg	52	7	uroepithelial	uroepithelial	JJ
cord-287670-z6ckhkgg	52	8	cells	cell	NNS
cord-287670-z6ckhkgg	52	9	has	have	VBZ
cord-287670-z6ckhkgg	52	10	been	be	VBN
cord-287670-z6ckhkgg	52	11	shown	show	VBN
cord-287670-z6ckhkgg	52	12	to	to	TO
cord-287670-z6ckhkgg	52	13	be	be	VB
cord-287670-z6ckhkgg	52	14	under	under	IN
cord-287670-z6ckhkgg	52	15	the	the	DT
cord-287670-z6ckhkgg	52	16	control	control	NN
cord-287670-z6ckhkgg	52	17	of	of	IN
cord-287670-z6ckhkgg	52	18	the	the	DT
cord-287670-z6ckhkgg	52	19	TLR4	TLR4	NNP
cord-287670-z6ckhkgg	52	20	/	/	SYM
cord-287670-z6ckhkgg	52	21	MyD88	MyD88	NNP
cord-287670-z6ckhkgg	52	22	signaling	signal	VBG
cord-287670-z6ckhkgg	52	23	pathway	pathway	NN
cord-287670-z6ckhkgg	52	24	[	[	-LRB-
cord-287670-z6ckhkgg	52	25	14	14	CD
cord-287670-z6ckhkgg	52	26	]	]	-RRB-
cord-287670-z6ckhkgg	52	27	.	.	.
cord-287670-z6ckhkgg	53	1	Accordingly	accordingly	RB
cord-287670-z6ckhkgg	53	2	,	,	,
cord-287670-z6ckhkgg	53	3	the	the	DT
cord-287670-z6ckhkgg	53	4	human	human	JJ
cord-287670-z6ckhkgg	53	5	and	and	CC
cord-287670-z6ckhkgg	53	6	murine	murine	JJ
cord-287670-z6ckhkgg	53	7	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	53	8	gene	gene	NN
cord-287670-z6ckhkgg	53	9	promoters	promoter	NNS
cord-287670-z6ckhkgg	53	10	have	have	VBP
cord-287670-z6ckhkgg	53	11	potential	potential	JJ
cord-287670-z6ckhkgg	53	12	binding	bind	VBG
cord-287670-z6ckhkgg	53	13	sites	site	NNS
cord-287670-z6ckhkgg	53	14	for	for	IN
cord-287670-z6ckhkgg	53	15	many	many	JJ
cord-287670-z6ckhkgg	53	16	inflammatory	inflammatory	JJ
cord-287670-z6ckhkgg	53	17	transcription	transcription	NN
cord-287670-z6ckhkgg	53	18	factors	factor	NNS
cord-287670-z6ckhkgg	53	19	,	,	,
cord-287670-z6ckhkgg	53	20	including	include	VBG
cord-287670-z6ckhkgg	53	21	PU.1	PU.1	NNP
cord-287670-z6ckhkgg	53	22	,	,	,
cord-287670-z6ckhkgg	53	23	AP-1	AP-1	NNP
cord-287670-z6ckhkgg	53	24	,	,	,
cord-287670-z6ckhkgg	53	25	NF	NF	NNP
cord-287670-z6ckhkgg	53	26	-	-	HYPH
cord-287670-z6ckhkgg	53	27	kB	kB	NNP
cord-287670-z6ckhkgg	53	28	,	,	,
cord-287670-z6ckhkgg	53	29	Sp-1	Sp-1	NNP
cord-287670-z6ckhkgg	53	30	,	,	,
cord-287670-z6ckhkgg	53	31	and	and	CC
cord-287670-z6ckhkgg	54	1	NF	NF	NNP
cord-287670-z6ckhkgg	54	2	-	-	HYPH
cord-287670-z6ckhkgg	54	3	IL-6	IL-6	NNP
cord-287670-z6ckhkgg	54	4	[	[	-LRB-
cord-287670-z6ckhkgg	54	5	23	23	CD
cord-287670-z6ckhkgg	54	6	,	,	,
cord-287670-z6ckhkgg	54	7	24	24	CD
cord-287670-z6ckhkgg	54	8	]	]	-RRB-
cord-287670-z6ckhkgg	54	9	.	.	.
cord-287670-z6ckhkgg	55	1	The	the	DT
cord-287670-z6ckhkgg	55	2	PI3K	PI3K	NNP
cord-287670-z6ckhkgg	55	3	/	/	SYM
cord-287670-z6ckhkgg	55	4	Akt	Akt	NNP
cord-287670-z6ckhkgg	55	5	axis	axis	NN
cord-287670-z6ckhkgg	55	6	and	and	CC
cord-287670-z6ckhkgg	55	7	JNK	JNK	NNP
cord-287670-z6ckhkgg	55	8	have	have	VBP
cord-287670-z6ckhkgg	55	9	also	also	RB
cord-287670-z6ckhkgg	55	10	been	be	VBN
cord-287670-z6ckhkgg	55	11	shown	show	VBN
cord-287670-z6ckhkgg	55	12	to	to	TO
cord-287670-z6ckhkgg	55	13	activate	activate	VB
cord-287670-z6ckhkgg	55	14	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	55	15	transcription	transcription	NN
cord-287670-z6ckhkgg	55	16	[	[	-LRB-
cord-287670-z6ckhkgg	55	17	14	14	CD
cord-287670-z6ckhkgg	55	18	]	]	-RRB-
cord-287670-z6ckhkgg	55	19	.	.	.
cord-287670-z6ckhkgg	56	1	In	in	IN
cord-287670-z6ckhkgg	56	2	addition	addition	NN
cord-287670-z6ckhkgg	56	3	,	,	,
cord-287670-z6ckhkgg	56	4	epigenetic	epigenetic	JJ
cord-287670-z6ckhkgg	56	5	mechanisms	mechanism	NNS
cord-287670-z6ckhkgg	56	6	have	have	VBP
cord-287670-z6ckhkgg	56	7	been	be	VBN
cord-287670-z6ckhkgg	56	8	implicated	implicate	VBN
cord-287670-z6ckhkgg	56	9	in	in	IN
cord-287670-z6ckhkgg	56	10	the	the	DT
cord-287670-z6ckhkgg	56	11	regulation	regulation	NN
cord-287670-z6ckhkgg	56	12	of	of	IN
cord-287670-z6ckhkgg	56	13	human	human	JJ
cord-287670-z6ckhkgg	56	14	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	56	15	expression	expression	NN
cord-287670-z6ckhkgg	56	16	,	,	,
cord-287670-z6ckhkgg	56	17	since	since	IN
cord-287670-z6ckhkgg	56	18	methylation	methylation	NN
cord-287670-z6ckhkgg	56	19	of	of	IN
cord-287670-z6ckhkgg	56	20	a	a	DT
cord-287670-z6ckhkgg	56	21	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	56	22	Glossary	Glossary	NNP
cord-287670-z6ckhkgg	56	23	Arthritogenic	Arthritogenic	NNP
cord-287670-z6ckhkgg	56	24	alphaviruses	alphavirus	NNS
cord-287670-z6ckhkgg	56	25	:	:	:
cord-287670-z6ckhkgg	56	26	include	include	VBP
cord-287670-z6ckhkgg	56	27	viruses	virus	NNS
cord-287670-z6ckhkgg	56	28	such	such	JJ
cord-287670-z6ckhkgg	56	29	as	as	IN
cord-287670-z6ckhkgg	56	30	CHIKV	CHIKV	NNP
cord-287670-z6ckhkgg	56	31	and	and	CC
cord-287670-z6ckhkgg	56	32	RRV	RRV	NNP
cord-287670-z6ckhkgg	56	33	.	.	.
cord-287670-z6ckhkgg	57	1	They	-PRON-	PRP
cord-287670-z6ckhkgg	57	2	are	be	VBP
cord-287670-z6ckhkgg	57	3	enveloped	envelop	VBN
cord-287670-z6ckhkgg	57	4	,	,	,
cord-287670-z6ckhkgg	57	5	positive	positive	JJ
cord-287670-z6ckhkgg	57	6	-	-	HYPH
cord-287670-z6ckhkgg	57	7	sense	sense	NN
cord-287670-z6ckhkgg	57	8	,	,	,
cord-287670-z6ckhkgg	57	9	single	single	RB
cord-287670-z6ckhkgg	57	10	-	-	HYPH
cord-287670-z6ckhkgg	57	11	stranded	strand	VBN
cord-287670-z6ckhkgg	57	12	RNA	RNA	NNP
cord-287670-z6ckhkgg	57	13	viruses	virus	NNS
cord-287670-z6ckhkgg	57	14	that	that	WDT
cord-287670-z6ckhkgg	57	15	are	be	VBP
cord-287670-z6ckhkgg	57	16	usually	usually	RB
cord-287670-z6ckhkgg	57	17	transmitted	transmit	VBN
cord-287670-z6ckhkgg	57	18	by	by	IN
cord-287670-z6ckhkgg	57	19	mosquitoes	mosquito	NNS
cord-287670-z6ckhkgg	57	20	and	and	CC
cord-287670-z6ckhkgg	57	21	cause	cause	VB
cord-287670-z6ckhkgg	57	22	rheumatic	rheumatic	JJ
cord-287670-z6ckhkgg	57	23	disease	disease	NN
cord-287670-z6ckhkgg	57	24	.	.	.
cord-287670-z6ckhkgg	58	1	C1q	c1q	NN
cord-287670-z6ckhkgg	58	2	:	:	:
cord-287670-z6ckhkgg	59	1	subcomponent	subcomponent	NN
cord-287670-z6ckhkgg	59	2	of	of	IN
cord-287670-z6ckhkgg	59	3	complement	complement	NN
cord-287670-z6ckhkgg	59	4	C1	C1	NNP
cord-287670-z6ckhkgg	59	5	.	.	.
cord-287670-z6ckhkgg	60	1	C1q	C1q	NNP
cord-287670-z6ckhkgg	60	2	has	have	VBZ
cord-287670-z6ckhkgg	60	3	binding	bind	VBG
cord-287670-z6ckhkgg	60	4	sites	site	NNS
cord-287670-z6ckhkgg	60	5	for	for	IN
cord-287670-z6ckhkgg	60	6	antibodies	antibody	NNS
cord-287670-z6ckhkgg	60	7	and	and	CC
cord-287670-z6ckhkgg	60	8	initiates	initiate	VBZ
cord-287670-z6ckhkgg	60	9	the	the	DT
cord-287670-z6ckhkgg	60	10	complement	complement	NN
cord-287670-z6ckhkgg	60	11	cascade	cascade	NN
cord-287670-z6ckhkgg	60	12	via	via	IN
cord-287670-z6ckhkgg	60	13	the	the	DT
cord-287670-z6ckhkgg	60	14	classical	classical	JJ
cord-287670-z6ckhkgg	60	15	pathway	pathway	NN
cord-287670-z6ckhkgg	60	16	.	.	.
cord-287670-z6ckhkgg	61	1	Collectins	Collectins	NNP
cord-287670-z6ckhkgg	61	2	:	:	:
cord-287670-z6ckhkgg	61	3	oligomeric	oligomeric	JJ
cord-287670-z6ckhkgg	61	4	proteins	protein	NNS
cord-287670-z6ckhkgg	61	5	containing	contain	VBG
cord-287670-z6ckhkgg	61	6	a	a	DT
cord-287670-z6ckhkgg	61	7	C	c	NN
cord-287670-z6ckhkgg	61	8	-	-	HYPH
cord-287670-z6ckhkgg	61	9	terminal	terminal	NN
cord-287670-z6ckhkgg	61	10	carbohydrate	carbohydrate	NN
cord-287670-z6ckhkgg	61	11	recognition	recognition	NN
cord-287670-z6ckhkgg	61	12	domain	domain	NN
cord-287670-z6ckhkgg	61	13	linked	link	VBN
cord-287670-z6ckhkgg	61	14	to	to	IN
cord-287670-z6ckhkgg	61	15	a	a	DT
cord-287670-z6ckhkgg	61	16	collagen	collagen	NN
cord-287670-z6ckhkgg	61	17	-	-	HYPH
cord-287670-z6ckhkgg	61	18	like	like	JJ
cord-287670-z6ckhkgg	61	19	region	region	NN
cord-287670-z6ckhkgg	61	20	through	through	IN
cord-287670-z6ckhkgg	61	21	an	an	DT
cord-287670-z6ckhkgg	61	22	alphahelical	alphahelical	JJ
cord-287670-z6ckhkgg	61	23	hydrophobic	hydrophobic	JJ
cord-287670-z6ckhkgg	61	24	neck	neck	NN
cord-287670-z6ckhkgg	61	25	region	region	NN
cord-287670-z6ckhkgg	61	26	and	and	CC
cord-287670-z6ckhkgg	61	27	an	an	DT
cord-287670-z6ckhkgg	61	28	N	n	CD
cord-287670-z6ckhkgg	61	29	-	-	HYPH
cord-287670-z6ckhkgg	61	30	terminal	terminal	NN
cord-287670-z6ckhkgg	61	31	region	region	NN
cord-287670-z6ckhkgg	61	32	.	.	.
cord-287670-z6ckhkgg	62	1	They	-PRON-	PRP
cord-287670-z6ckhkgg	62	2	have	have	VBP
cord-287670-z6ckhkgg	62	3	the	the	DT
cord-287670-z6ckhkgg	62	4	capacity	capacity	NN
cord-287670-z6ckhkgg	62	5	to	to	TO
cord-287670-z6ckhkgg	62	6	interact	interact	VB
cord-287670-z6ckhkgg	62	7	with	with	IN
cord-287670-z6ckhkgg	62	8	carbohydrates	carbohydrate	NNS
cord-287670-z6ckhkgg	62	9	and	and	CC
cord-287670-z6ckhkgg	62	10	lipids	lipid	NNS
cord-287670-z6ckhkgg	62	11	exposed	expose	VBN
cord-287670-z6ckhkgg	62	12	on	on	IN
cord-287670-z6ckhkgg	62	13	pathogen	pathogen	NN
cord-287670-z6ckhkgg	62	14	surfaces	surface	NNS
cord-287670-z6ckhkgg	62	15	.	.	.
cord-287670-z6ckhkgg	63	1	They	-PRON-	PRP
cord-287670-z6ckhkgg	63	2	also	also	RB
cord-287670-z6ckhkgg	63	3	bear	bear	VBP
cord-287670-z6ckhkgg	63	4	opsonic	opsonic	JJ
cord-287670-z6ckhkgg	63	5	activity	activity	NN
cord-287670-z6ckhkgg	63	6	and	and	CC
cord-287670-z6ckhkgg	63	7	can	can	MD
cord-287670-z6ckhkgg	63	8	activate	activate	VB
cord-287670-z6ckhkgg	63	9	the	the	DT
cord-287670-z6ckhkgg	63	10	lectin	lectin	NN
cord-287670-z6ckhkgg	63	11	pathway	pathway	NN
cord-287670-z6ckhkgg	63	12	of	of	IN
cord-287670-z6ckhkgg	63	13	the	the	DT
cord-287670-z6ckhkgg	63	14	complement	complement	JJ
cord-287670-z6ckhkgg	63	15	system	system	NN
cord-287670-z6ckhkgg	63	16	.	.	.
cord-287670-z6ckhkgg	64	1	Complement	complement	JJ
cord-287670-z6ckhkgg	64	2	cascade	cascade	NN
cord-287670-z6ckhkgg	64	3	:	:	:
cord-287670-z6ckhkgg	64	4	a	a	DT
cord-287670-z6ckhkgg	64	5	multimolecular	multimolecular	JJ
cord-287670-z6ckhkgg	64	6	biologic	biologic	JJ
cord-287670-z6ckhkgg	64	7	process	process	NN
cord-287670-z6ckhkgg	64	8	sustained	sustain	VBN
cord-287670-z6ckhkgg	64	9	by	by	IN
cord-287670-z6ckhkgg	64	10	more	more	JJR
cord-287670-z6ckhkgg	64	11	than	than	IN
cord-287670-z6ckhkgg	64	12	20	20	CD
cord-287670-z6ckhkgg	64	13	proteins	protein	NNS
cord-287670-z6ckhkgg	64	14	.	.	.
cord-287670-z6ckhkgg	65	1	These	these	DT
cord-287670-z6ckhkgg	65	2	molecules	molecule	NNS
cord-287670-z6ckhkgg	65	3	act	act	VBP
cord-287670-z6ckhkgg	65	4	in	in	IN
cord-287670-z6ckhkgg	65	5	concert	concert	NN
cord-287670-z6ckhkgg	65	6	and	and	CC
cord-287670-z6ckhkgg	65	7	in	in	IN
cord-287670-z6ckhkgg	65	8	a	a	DT
cord-287670-z6ckhkgg	65	9	specific	specific	JJ
cord-287670-z6ckhkgg	65	10	sequence	sequence	NN
cord-287670-z6ckhkgg	65	11	called	call	VBN
cord-287670-z6ckhkgg	65	12	the	the	DT
cord-287670-z6ckhkgg	65	13	complement	complement	NN
cord-287670-z6ckhkgg	65	14	cascade	cascade	NN
cord-287670-z6ckhkgg	65	15	.	.	.
cord-287670-z6ckhkgg	66	1	Three	three	CD
cord-287670-z6ckhkgg	66	2	different	different	JJ
cord-287670-z6ckhkgg	66	3	pathways	pathway	NNS
cord-287670-z6ckhkgg	66	4	(	(	-LRB-
cord-287670-z6ckhkgg	66	5	i.e.	i.e.	FW
cord-287670-z6ckhkgg	66	6	,	,	,
cord-287670-z6ckhkgg	66	7	the	the	DT
cord-287670-z6ckhkgg	66	8	classical	classical	JJ
cord-287670-z6ckhkgg	66	9	pathway	pathway	NN
cord-287670-z6ckhkgg	66	10	,	,	,
cord-287670-z6ckhkgg	66	11	alternative	alternative	JJ
cord-287670-z6ckhkgg	66	12	pathway	pathway	NN
cord-287670-z6ckhkgg	66	13	,	,	,
cord-287670-z6ckhkgg	66	14	and	and	CC
cord-287670-z6ckhkgg	66	15	lectin	lectin	NN
cord-287670-z6ckhkgg	66	16	pathway	pathway	NN
cord-287670-z6ckhkgg	66	17	)	)	-RRB-
cord-287670-z6ckhkgg	66	18	can	can	MD
cord-287670-z6ckhkgg	66	19	be	be	VB
cord-287670-z6ckhkgg	66	20	activated	activate	VBN
cord-287670-z6ckhkgg	66	21	.	.	.
cord-287670-z6ckhkgg	67	1	The	the	DT
cord-287670-z6ckhkgg	67	2	terminal	terminal	JJ
cord-287670-z6ckhkgg	67	3	pathway	pathway	NN
cord-287670-z6ckhkgg	67	4	of	of	IN
cord-287670-z6ckhkgg	67	5	the	the	DT
cord-287670-z6ckhkgg	67	6	complement	complement	NN
cord-287670-z6ckhkgg	67	7	cascade	cascade	NN
cord-287670-z6ckhkgg	67	8	leads	lead	NNS
cord-287670-z6ckhkgg	67	9	to	to	IN
cord-287670-z6ckhkgg	67	10	the	the	DT
cord-287670-z6ckhkgg	67	11	formation	formation	NN
cord-287670-z6ckhkgg	67	12	of	of	IN
cord-287670-z6ckhkgg	67	13	a	a	DT
cord-287670-z6ckhkgg	67	14	membrane	membrane	NN
cord-287670-z6ckhkgg	67	15	-	-	HYPH
cord-287670-z6ckhkgg	67	16	attack	attack	NN
cord-287670-z6ckhkgg	67	17	complex	complex	NN
cord-287670-z6ckhkgg	67	18	on	on	IN
cord-287670-z6ckhkgg	67	19	target	target	NN
cord-287670-z6ckhkgg	67	20	surfaces	surface	NNS
cord-287670-z6ckhkgg	67	21	,	,	,
cord-287670-z6ckhkgg	67	22	which	which	WDT
cord-287670-z6ckhkgg	67	23	induces	induce	VBZ
cord-287670-z6ckhkgg	67	24	cell	cell	NN
cord-287670-z6ckhkgg	67	25	lysis	lysis	NN
cord-287670-z6ckhkgg	67	26	.	.	.
cord-287670-z6ckhkgg	68	1	Conidia	Conidia	NNP
cord-287670-z6ckhkgg	68	2	:	:	:
cord-287670-z6ckhkgg	68	3	also	also	RB
cord-287670-z6ckhkgg	68	4	called	call	VBN
cord-287670-z6ckhkgg	68	5	chlamidospores	chlamidospore	NNS
cord-287670-z6ckhkgg	68	6	or	or	CC
cord-287670-z6ckhkgg	68	7	mitospores	mitospores	NNP
cord-287670-z6ckhkgg	68	8	;	;	,
cord-287670-z6ckhkgg	68	9	asexual	asexual	JJ
cord-287670-z6ckhkgg	68	10	,	,	,
cord-287670-z6ckhkgg	68	11	nonmotile	nonmotile	JJ
cord-287670-z6ckhkgg	68	12	spores	spore	NNS
cord-287670-z6ckhkgg	68	13	of	of	IN
cord-287670-z6ckhkgg	68	14	a	a	DT
cord-287670-z6ckhkgg	68	15	fungus	fungus	NN
cord-287670-z6ckhkgg	68	16	.	.	.
cord-287670-z6ckhkgg	69	1	They	-PRON-	PRP
cord-287670-z6ckhkgg	69	2	develop	develop	VBP
cord-287670-z6ckhkgg	69	3	at	at	IN
cord-287670-z6ckhkgg	69	4	the	the	DT
cord-287670-z6ckhkgg	69	5	tip	tip	NN
cord-287670-z6ckhkgg	69	6	of	of	IN
cord-287670-z6ckhkgg	69	7	specialized	specialized	JJ
cord-287670-z6ckhkgg	69	8	hyphae	hypha	NNS
cord-287670-z6ckhkgg	69	9	in	in	IN
cord-287670-z6ckhkgg	69	10	fungi	fungus	NNS
cord-287670-z6ckhkgg	69	11	called	call	VBN
cord-287670-z6ckhkgg	69	12	conidiophores	conidiophores	NNP
cord-287670-z6ckhkgg	69	13	and	and	CC
cord-287670-z6ckhkgg	69	14	are	be	VBP
cord-287670-z6ckhkgg	69	15	formed	form	VBN
cord-287670-z6ckhkgg	69	16	by	by	IN
cord-287670-z6ckhkgg	69	17	the	the	DT
cord-287670-z6ckhkgg	69	18	abstriction	abstriction	NN
cord-287670-z6ckhkgg	69	19	at	at	IN
cord-287670-z6ckhkgg	69	20	the	the	DT
cord-287670-z6ckhkgg	69	21	top	top	NN
cord-287670-z6ckhkgg	69	22	of	of	IN
cord-287670-z6ckhkgg	69	23	a	a	DT
cord-287670-z6ckhkgg	69	24	hyphal	hyphal	NN
cord-287670-z6ckhkgg	69	25	branch	branch	NN
cord-287670-z6ckhkgg	69	26	.	.	.
cord-287670-z6ckhkgg	70	1	This	this	DT
cord-287670-z6ckhkgg	70	2	process	process	NN
cord-287670-z6ckhkgg	70	3	induces	induce	VBZ
cord-287670-z6ckhkgg	70	4	the	the	DT
cord-287670-z6ckhkgg	70	5	separation	separation	NN
cord-287670-z6ckhkgg	70	6	and	and	CC
cord-287670-z6ckhkgg	70	7	release	release	NN
cord-287670-z6ckhkgg	70	8	of	of	IN
cord-287670-z6ckhkgg	70	9	a	a	DT
cord-287670-z6ckhkgg	70	10	mature	mature	JJ
cord-287670-z6ckhkgg	70	11	spore	spore	NN
cord-287670-z6ckhkgg	70	12	by	by	IN
cord-287670-z6ckhkgg	70	13	the	the	DT
cord-287670-z6ckhkgg	70	14	formation	formation	NN
cord-287670-z6ckhkgg	70	15	of	of	IN
cord-287670-z6ckhkgg	70	16	a	a	DT
cord-287670-z6ckhkgg	70	17	septum	septum	NN
cord-287670-z6ckhkgg	70	18	.	.	.
cord-287670-z6ckhkgg	71	1	Cumulus	cumulus	NN
cord-287670-z6ckhkgg	71	2	cells	cell	NNS
cord-287670-z6ckhkgg	71	3	:	:	:
cord-287670-z6ckhkgg	71	4	a	a	DT
cord-287670-z6ckhkgg	71	5	cluster	cluster	NN
cord-287670-z6ckhkgg	71	6	of	of	IN
cord-287670-z6ckhkgg	71	7	cells	cell	NNS
cord-287670-z6ckhkgg	71	8	forming	form	VBG
cord-287670-z6ckhkgg	71	9	the	the	DT
cord-287670-z6ckhkgg	71	10	cumulus	cumulus	NN
cord-287670-z6ckhkgg	71	11	oophorus	oophorus	NNP
cord-287670-z6ckhkgg	71	12	,	,	,
cord-287670-z6ckhkgg	71	13	which	which	WDT
cord-287670-z6ckhkgg	71	14	is	be	VBZ
cord-287670-z6ckhkgg	71	15	a	a	DT
cord-287670-z6ckhkgg	71	16	follicular	follicular	JJ
cord-287670-z6ckhkgg	71	17	mass	mass	NN
cord-287670-z6ckhkgg	71	18	surrounding	surround	VBG
cord-287670-z6ckhkgg	71	19	the	the	DT
cord-287670-z6ckhkgg	71	20	oocyte	oocyte	NN
cord-287670-z6ckhkgg	71	21	in	in	IN
cord-287670-z6ckhkgg	71	22	the	the	DT
cord-287670-z6ckhkgg	71	23	ovarian	ovarian	JJ
cord-287670-z6ckhkgg	71	24	follicle	follicle	NN
cord-287670-z6ckhkgg	71	25	.	.	.
cord-287670-z6ckhkgg	72	1	Damage	damage	NN
cord-287670-z6ckhkgg	72	2	-	-	HYPH
cord-287670-z6ckhkgg	72	3	associated	associate	VBN
cord-287670-z6ckhkgg	72	4	molecular	molecular	JJ
cord-287670-z6ckhkgg	72	5	patterns	pattern	NNS
cord-287670-z6ckhkgg	72	6	(	(	-LRB-
cord-287670-z6ckhkgg	72	7	DAMPs	damp	NNS
cord-287670-z6ckhkgg	72	8	)	)	-RRB-
cord-287670-z6ckhkgg	72	9	:	:	:
cord-287670-z6ckhkgg	72	10	also	also	RB
cord-287670-z6ckhkgg	72	11	known	know	VBN
cord-287670-z6ckhkgg	72	12	as	as	IN
cord-287670-z6ckhkgg	72	13	danger	danger	NN
cord-287670-z6ckhkgg	72	14	-	-	HYPH
cord-287670-z6ckhkgg	72	15	associated	associate	VBN
cord-287670-z6ckhkgg	72	16	molecular	molecular	JJ
cord-287670-z6ckhkgg	72	17	patterns	pattern	NNS
cord-287670-z6ckhkgg	72	18	or	or	CC
cord-287670-z6ckhkgg	72	19	endogenous	endogenous	JJ
cord-287670-z6ckhkgg	72	20	alarmins	alarmin	NNS
cord-287670-z6ckhkgg	72	21	;	;	:
cord-287670-z6ckhkgg	72	22	host	host	NN
cord-287670-z6ckhkgg	72	23	cellderived	cellderived	JJ
cord-287670-z6ckhkgg	72	24	molecules	molecule	NNS
cord-287670-z6ckhkgg	72	25	released	release	VBN
cord-287670-z6ckhkgg	72	26	by	by	IN
cord-287670-z6ckhkgg	72	27	stressed	stressed	JJ
cord-287670-z6ckhkgg	72	28	cells	cell	NNS
cord-287670-z6ckhkgg	72	29	and	and	CC
cord-287670-z6ckhkgg	72	30	necrotic	necrotic	JJ
cord-287670-z6ckhkgg	72	31	cells	cell	NNS
cord-287670-z6ckhkgg	72	32	(	(	-LRB-
cord-287670-z6ckhkgg	72	33	e.g.	e.g.	RB
cord-287670-z6ckhkgg	72	34	,	,	,
cord-287670-z6ckhkgg	72	35	HMGB1	HMGB1	NNP
cord-287670-z6ckhkgg	72	36	,	,	,
cord-287670-z6ckhkgg	72	37	IL-1/	IL-1/	NNP
cord-287670-z6ckhkgg	72	38	)	)	-RRB-
cord-287670-z6ckhkgg	72	39	.	.	.
cord-287670-z6ckhkgg	73	1	DAMPs	damp	NNS
cord-287670-z6ckhkgg	73	2	can	can	MD
cord-287670-z6ckhkgg	73	3	engage	engage	VB
cord-287670-z6ckhkgg	73	4	receptors	receptor	NNS
cord-287670-z6ckhkgg	73	5	(	(	-LRB-
cord-287670-z6ckhkgg	73	6	e.g.	e.g.	RB
cord-287670-z6ckhkgg	73	7	,	,	,
cord-287670-z6ckhkgg	73	8	TLRs	TLRs	NNP
cord-287670-z6ckhkgg	73	9	)	)	-RRB-
cord-287670-z6ckhkgg	73	10	to	to	TO
cord-287670-z6ckhkgg	73	11	induce	induce	VB
cord-287670-z6ckhkgg	73	12	and	and	CC
cord-287670-z6ckhkgg	73	13	sustain	sustain	VB
cord-287670-z6ckhkgg	73	14	the	the	DT
cord-287670-z6ckhkgg	73	15	inflammatory	inflammatory	JJ
cord-287670-z6ckhkgg	73	16	response	response	NN
cord-287670-z6ckhkgg	73	17	.	.	.
cord-287670-z6ckhkgg	74	1	Fcg	Fcg	NNS
cord-287670-z6ckhkgg	74	2	receptors	receptor	NNS
cord-287670-z6ckhkgg	74	3	(	(	-LRB-
cord-287670-z6ckhkgg	74	4	FcgRs	fcgrs	NN
cord-287670-z6ckhkgg	74	5	)	)	-RRB-
cord-287670-z6ckhkgg	74	6	:	:	:
cord-287670-z6ckhkgg	74	7	receptors	receptor	NNS
cord-287670-z6ckhkgg	74	8	for	for	IN
cord-287670-z6ckhkgg	74	9	the	the	DT
cord-287670-z6ckhkgg	74	10	Fc	Fc	NNP
cord-287670-z6ckhkgg	74	11	(	(	-LRB-
cord-287670-z6ckhkgg	74	12	tail	tail	NN
cord-287670-z6ckhkgg	74	13	)	)	-RRB-
cord-287670-z6ckhkgg	74	14	region	region	NN
cord-287670-z6ckhkgg	74	15	of	of	IN
cord-287670-z6ckhkgg	74	16	IgG.	IgG.	NNP
cord-287670-z6ckhkgg	75	1	Based	base	VBN
cord-287670-z6ckhkgg	75	2	on	on	IN
cord-287670-z6ckhkgg	75	3	their	-PRON-	PRP$
cord-287670-z6ckhkgg	75	4	structure	structure	NN
cord-287670-z6ckhkgg	75	5	,	,	,
cord-287670-z6ckhkgg	75	6	they	-PRON-	PRP
cord-287670-z6ckhkgg	75	7	comprise	comprise	VBP
cord-287670-z6ckhkgg	75	8	FcgRI	FcgRI	NNP
cord-287670-z6ckhkgg	75	9	(	(	-LRB-
cord-287670-z6ckhkgg	75	10	CD64	CD64	NNP
cord-287670-z6ckhkgg	75	11	)	)	-RRB-
cord-287670-z6ckhkgg	75	12	,	,	.
cord-287670-z6ckhkgg	76	1	FcgRII	fcgrii	JJ
cord-287670-z6ckhkgg	76	2	(	(	-LRB-
cord-287670-z6ckhkgg	76	3	CD32	CD32	NNP
cord-287670-z6ckhkgg	76	4	)	)	-RRB-
cord-287670-z6ckhkgg	76	5	,	,	,
cord-287670-z6ckhkgg	76	6	and	and	CC
cord-287670-z6ckhkgg	76	7	FcgRIII	FcgRIII	NNP
cord-287670-z6ckhkgg	76	8	(	(	-LRB-
cord-287670-z6ckhkgg	76	9	CD16	CD16	NNP
cord-287670-z6ckhkgg	76	10	)	)	-RRB-
cord-287670-z6ckhkgg	76	11	.	.	.
cord-287670-z6ckhkgg	77	1	FcgRs	FcgRs	NNP
cord-287670-z6ckhkgg	77	2	participate	participate	VB
cord-287670-z6ckhkgg	77	3	in	in	IN
cord-287670-z6ckhkgg	77	4	the	the	DT
cord-287670-z6ckhkgg	77	5	regulation	regulation	NN
cord-287670-z6ckhkgg	77	6	of	of	IN
cord-287670-z6ckhkgg	77	7	the	the	DT
cord-287670-z6ckhkgg	77	8	immune	immune	JJ
cord-287670-z6ckhkgg	77	9	response	response	NN
cord-287670-z6ckhkgg	77	10	.	.	.
cord-287670-z6ckhkgg	78	1	Besides	besides	IN
cord-287670-z6ckhkgg	78	2	their	-PRON-	PRP$
cord-287670-z6ckhkgg	78	3	capacity	capacity	NN
cord-287670-z6ckhkgg	78	4	to	to	TO
cord-287670-z6ckhkgg	78	5	recognize	recognize	VB
cord-287670-z6ckhkgg	78	6	IgG	IgG	NNP
cord-287670-z6ckhkgg	78	7	,	,	,
cord-287670-z6ckhkgg	78	8	FcgRs	FcgRs	NNP
cord-287670-z6ckhkgg	78	9	can	can	MD
cord-287670-z6ckhkgg	78	10	act	act	VB
cord-287670-z6ckhkgg	78	11	as	as	IN
cord-287670-z6ckhkgg	78	12	receptors	receptor	NNS
cord-287670-z6ckhkgg	78	13	for	for	IN
cord-287670-z6ckhkgg	78	14	opsonins	opsonins	NNP
cord-287670-z6ckhkgg	78	15	(	(	-LRB-
cord-287670-z6ckhkgg	78	16	e.g.	e.g.	RB
cord-287670-z6ckhkgg	78	17	,	,	,
cord-287670-z6ckhkgg	78	18	pentraxins	pentraxins	NNP
cord-287670-z6ckhkgg	78	19	)	)	-RRB-
cord-287670-z6ckhkgg	78	20	.	.	.
cord-287670-z6ckhkgg	79	1	M2-like	M2-like	NNP
cord-287670-z6ckhkgg	79	2	polarization	polarization	NN
cord-287670-z6ckhkgg	79	3	:	:	:
cord-287670-z6ckhkgg	79	4	in	in	IN
cord-287670-z6ckhkgg	79	5	response	response	NN
cord-287670-z6ckhkgg	79	6	to	to	IN
cord-287670-z6ckhkgg	79	7	external	external	JJ
cord-287670-z6ckhkgg	79	8	signals	signal	NNS
cord-287670-z6ckhkgg	79	9	,	,	,
cord-287670-z6ckhkgg	79	10	macrophages	macrophage	NNS
cord-287670-z6ckhkgg	79	11	can	can	MD
cord-287670-z6ckhkgg	79	12	undergo	undergo	VB
cord-287670-z6ckhkgg	79	13	M1	M1	NNP
cord-287670-z6ckhkgg	79	14	activation	activation	NN
cord-287670-z6ckhkgg	79	15	(	(	-LRB-
cord-287670-z6ckhkgg	79	16	also	also	RB
cord-287670-z6ckhkgg	79	17	called	call	VBN
cord-287670-z6ckhkgg	79	18	classical	classical	JJ
cord-287670-z6ckhkgg	79	19	activation	activation	NN
cord-287670-z6ckhkgg	79	20	)	)	-RRB-
cord-287670-z6ckhkgg	79	21	on	on	IN
cord-287670-z6ckhkgg	79	22	stimulation	stimulation	NN
cord-287670-z6ckhkgg	79	23	by	by	IN
cord-287670-z6ckhkgg	79	24	TLR	TLR	NNP
cord-287670-z6ckhkgg	79	25	ligands	ligand	NNS
cord-287670-z6ckhkgg	79	26	and	and	CC
cord-287670-z6ckhkgg	79	27	IFNg	IFNg	NNS
cord-287670-z6ckhkgg	79	28	or	or	CC
cord-287670-z6ckhkgg	79	29	M2	M2	NNP
cord-287670-z6ckhkgg	79	30	activation	activation	NN
cord-287670-z6ckhkgg	79	31	(	(	-LRB-
cord-287670-z6ckhkgg	79	32	also	also	RB
cord-287670-z6ckhkgg	79	33	called	call	VBN
cord-287670-z6ckhkgg	79	34	alternative	alternative	JJ
cord-287670-z6ckhkgg	79	35	activation	activation	NN
cord-287670-z6ckhkgg	79	36	)	)	-RRB-
cord-287670-z6ckhkgg	79	37	on	on	IN
cord-287670-z6ckhkgg	79	38	stimulation	stimulation	NN
cord-287670-z6ckhkgg	79	39	by	by	IN
cord-287670-z6ckhkgg	79	40	IL-4	IL-4	NNP
cord-287670-z6ckhkgg	79	41	/	/	SYM
cord-287670-z6ckhkgg	79	42	IL-13	IL-13	NNP
cord-287670-z6ckhkgg	79	43	.	.	.
cord-287670-z6ckhkgg	80	1	The	the	DT
cord-287670-z6ckhkgg	80	2	M2	M2	NNP
cord-287670-z6ckhkgg	80	3	or	or	CC
cord-287670-z6ckhkgg	80	4	M2-like	M2-like	NNP
cord-287670-z6ckhkgg	80	5	polarization	polarization	NN
cord-287670-z6ckhkgg	80	6	state	state	NN
cord-287670-z6ckhkgg	80	7	has	have	VBZ
cord-287670-z6ckhkgg	80	8	been	be	VBN
cord-287670-z6ckhkgg	80	9	associated	associate	VBN
cord-287670-z6ckhkgg	80	10	with	with	IN
cord-287670-z6ckhkgg	80	11	high	high	JJ
cord-287670-z6ckhkgg	80	12	production	production	NN
cord-287670-z6ckhkgg	80	13	of	of	IN
cord-287670-z6ckhkgg	80	14	IL-10	IL-10	NNP
cord-287670-z6ckhkgg	80	15	,	,	,
cord-287670-z6ckhkgg	80	16	low	low	JJ
cord-287670-z6ckhkgg	80	17	production	production	NN
cord-287670-z6ckhkgg	80	18	of	of	IN
cord-287670-z6ckhkgg	80	19	IL-12	IL-12	NNP
cord-287670-z6ckhkgg	80	20	,	,	,
cord-287670-z6ckhkgg	80	21	and	and	CC
cord-287670-z6ckhkgg	80	22	resolution	resolution	NN
cord-287670-z6ckhkgg	80	23	or	or	CC
cord-287670-z6ckhkgg	80	24	smoldering	smoldering	NN
cord-287670-z6ckhkgg	80	25	of	of	IN
cord-287670-z6ckhkgg	80	26	chronic	chronic	JJ
cord-287670-z6ckhkgg	80	27	inflammation	inflammation	NN
cord-287670-z6ckhkgg	80	28	.	.	.
cord-287670-z6ckhkgg	81	1	Neutrophil	Neutrophil	NNP
cord-287670-z6ckhkgg	81	2	extracellular	extracellular	JJ
cord-287670-z6ckhkgg	81	3	traps	trap	NNS
cord-287670-z6ckhkgg	81	4	(	(	-LRB-
cord-287670-z6ckhkgg	81	5	NETs	nets	NN
cord-287670-z6ckhkgg	81	6	)	)	-RRB-
cord-287670-z6ckhkgg	81	7	:	:	:
cord-287670-z6ckhkgg	81	8	extracellular	extracellular	JJ
cord-287670-z6ckhkgg	81	9	fibrillary	fibrillary	JJ
cord-287670-z6ckhkgg	81	10	networks	network	NNS
cord-287670-z6ckhkgg	81	11	formed	form	VBN
cord-287670-z6ckhkgg	81	12	and	and	CC
cord-287670-z6ckhkgg	81	13	released	release	VBN
cord-287670-z6ckhkgg	81	14	by	by	IN
cord-287670-z6ckhkgg	81	15	activated	activate	VBN
cord-287670-z6ckhkgg	81	16	neutrophils	neutrophil	NNS
cord-287670-z6ckhkgg	81	17	.	.	.
cord-287670-z6ckhkgg	82	1	NETs	net	NNS
cord-287670-z6ckhkgg	82	2	comprise	comprise	VBP
cord-287670-z6ckhkgg	82	3	DNA	dna	NN
cord-287670-z6ckhkgg	82	4	and	and	CC
cord-287670-z6ckhkgg	82	5	histones	histone	NNS
cord-287670-z6ckhkgg	82	6	and	and	CC
cord-287670-z6ckhkgg	82	7	contain	contain	VBP
cord-287670-z6ckhkgg	82	8	a	a	DT
cord-287670-z6ckhkgg	82	9	set	set	NN
cord-287670-z6ckhkgg	82	10	of	of	IN
cord-287670-z6ckhkgg	82	11	proteins	protein	NNS
cord-287670-z6ckhkgg	82	12	from	from	IN
cord-287670-z6ckhkgg	82	13	neutrophil	neutrophil	NN
cord-287670-z6ckhkgg	82	14	granules	granule	NNS
cord-287670-z6ckhkgg	82	15	(	(	-LRB-
cord-287670-z6ckhkgg	82	16	e.g.	e.g.	RB
cord-287670-z6ckhkgg	82	17	,	,	,
cord-287670-z6ckhkgg	82	18	MPO	MPO	NNP
cord-287670-z6ckhkgg	82	19	,	,	,
cord-287670-z6ckhkgg	82	20	neutrophil	neutrophil	NN
cord-287670-z6ckhkgg	82	21	elastase	elastase	NN
cord-287670-z6ckhkgg	82	22	,	,	,
cord-287670-z6ckhkgg	82	23	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	82	24	)	)	-RRB-
cord-287670-z6ckhkgg	82	25	.	.	.
cord-287670-z6ckhkgg	83	1	NETs	net	NNS
cord-287670-z6ckhkgg	83	2	have	have	VBP
cord-287670-z6ckhkgg	83	3	the	the	DT
cord-287670-z6ckhkgg	83	4	capacity	capacity	NN
cord-287670-z6ckhkgg	83	5	to	to	TO
cord-287670-z6ckhkgg	83	6	trap	trap	NN
cord-287670-z6ckhkgg	83	7	microbes	microbe	NNS
cord-287670-z6ckhkgg	83	8	and	and	CC
cord-287670-z6ckhkgg	83	9	favor	favor	VBP
cord-287670-z6ckhkgg	83	10	their	-PRON-	PRP$
cord-287670-z6ckhkgg	83	11	elimination	elimination	NN
cord-287670-z6ckhkgg	83	12	.	.	.
cord-287670-z6ckhkgg	84	1	Nucleotide	nucleotide	NN
cord-287670-z6ckhkgg	84	2	-	-	HYPH
cord-287670-z6ckhkgg	84	3	binding	bind	VBG
cord-287670-z6ckhkgg	84	4	oligomerization	oligomerization	NN
cord-287670-z6ckhkgg	84	5	domain	domain	NN
cord-287670-z6ckhkgg	84	6	(	(	-LRB-
cord-287670-z6ckhkgg	84	7	NOD	nod	NN
cord-287670-z6ckhkgg	84	8	)	)	-RRB-
cord-287670-z6ckhkgg	84	9	and	and	CC
cord-287670-z6ckhkgg	84	10	RIG	rig	NN
cord-287670-z6ckhkgg	84	11	-	-	HYPH
cord-287670-z6ckhkgg	84	12	like	like	JJ
cord-287670-z6ckhkgg	84	13	receptors	receptor	NNS
cord-287670-z6ckhkgg	84	14	:	:	:
cord-287670-z6ckhkgg	84	15	intracellular	intracellular	JJ
cord-287670-z6ckhkgg	84	16	sensors	sensor	NNS
cord-287670-z6ckhkgg	84	17	of	of	IN
cord-287670-z6ckhkgg	84	18	microbial	microbial	JJ
cord-287670-z6ckhkgg	84	19	moieties	moiety	NNS
cord-287670-z6ckhkgg	84	20	and	and	CC
cord-287670-z6ckhkgg	84	21	DAMPs	damp	NNS
cord-287670-z6ckhkgg	84	22	associated	associate	VBN
cord-287670-z6ckhkgg	84	23	with	with	IN
cord-287670-z6ckhkgg	84	24	cell	cell	NN
cord-287670-z6ckhkgg	84	25	stress	stress	NN
cord-287670-z6ckhkgg	84	26	or	or	CC
cord-287670-z6ckhkgg	84	27	viruses	virus	NNS
cord-287670-z6ckhkgg	84	28	,	,	,
cord-287670-z6ckhkgg	84	29	respectively	respectively	RB
cord-287670-z6ckhkgg	84	30	.	.	.
cord-287670-z6ckhkgg	85	1	Opsonic	opsonic	JJ
cord-287670-z6ckhkgg	85	2	activity	activity	NN
cord-287670-z6ckhkgg	85	3	:	:	:
cord-287670-z6ckhkgg	85	4	opsonization	opsonization	NN
cord-287670-z6ckhkgg	85	5	is	be	VBZ
cord-287670-z6ckhkgg	85	6	a	a	DT
cord-287670-z6ckhkgg	85	7	process	process	NN
cord-287670-z6ckhkgg	85	8	by	by	IN
cord-287670-z6ckhkgg	85	9	which	which	WDT
cord-287670-z6ckhkgg	85	10	a	a	DT
cord-287670-z6ckhkgg	85	11	molecule	molecule	NN
cord-287670-z6ckhkgg	85	12	(	(	-LRB-
cord-287670-z6ckhkgg	85	13	i.e.	i.e.	FW
cord-287670-z6ckhkgg	85	14	,	,	,
cord-287670-z6ckhkgg	85	15	opsonin	opsonin	FW
cord-287670-z6ckhkgg	85	16	)	)	-RRB-
cord-287670-z6ckhkgg	85	17	interacts	interact	VBZ
cord-287670-z6ckhkgg	85	18	with	with	IN
cord-287670-z6ckhkgg	85	19	microbes	microbe	NNS
cord-287670-z6ckhkgg	85	20	leading	lead	VBG
cord-287670-z6ckhkgg	85	21	to	to	IN
cord-287670-z6ckhkgg	85	22	facilitated	facilitate	VBN
cord-287670-z6ckhkgg	85	23	microbial	microbial	JJ
cord-287670-z6ckhkgg	85	24	recognition	recognition	NN
cord-287670-z6ckhkgg	85	25	and	and	CC
cord-287670-z6ckhkgg	85	26	elimination	elimination	NN
cord-287670-z6ckhkgg	85	27	by	by	IN
cord-287670-z6ckhkgg	85	28	phagocytosis	phagocytosis	NN
cord-287670-z6ckhkgg	85	29	.	.	.
cord-287670-z6ckhkgg	86	1	Pattern	pattern	NN
cord-287670-z6ckhkgg	86	2	recognition	recognition	NN
cord-287670-z6ckhkgg	86	3	molecules	molecule	NNS
cord-287670-z6ckhkgg	86	4	(	(	-LRB-
cord-287670-z6ckhkgg	86	5	PRMs	PRMs	NNP
cord-287670-z6ckhkgg	86	6	)	)	-RRB-
cord-287670-z6ckhkgg	86	7	:	:	:
cord-287670-z6ckhkgg	86	8	a	a	DT
cord-287670-z6ckhkgg	86	9	set	set	NN
cord-287670-z6ckhkgg	86	10	of	of	IN
cord-287670-z6ckhkgg	86	11	germline	germline	NN
cord-287670-z6ckhkgg	86	12	-	-	HYPH
cord-287670-z6ckhkgg	86	13	encoded	encode	VBN
cord-287670-z6ckhkgg	86	14	receptors	receptor	NNS
cord-287670-z6ckhkgg	86	15	used	use	VBN
cord-287670-z6ckhkgg	86	16	to	to	TO
cord-287670-z6ckhkgg	86	17	discriminate	discriminate	VB
cord-287670-z6ckhkgg	86	18	selfversus	selfversus	NNP
cord-287670-z6ckhkgg	86	19	non	non	JJ
cord-287670-z6ckhkgg	86	20	-	-	JJ
cord-287670-z6ckhkgg	86	21	self	self	JJ
cord-287670-z6ckhkgg	86	22	and	and	CC
cord-287670-z6ckhkgg	86	23	modified	modify	VBN
cord-287670-z6ckhkgg	86	24	-	-	HYPH
cord-287670-z6ckhkgg	86	25	self	self	NN
cord-287670-z6ckhkgg	86	26	antigens	antigen	NNS
cord-287670-z6ckhkgg	86	27	.	.	.
cord-287670-z6ckhkgg	87	1	Based	base	VBN
cord-287670-z6ckhkgg	87	2	on	on	IN
cord-287670-z6ckhkgg	87	3	their	-PRON-	PRP$
cord-287670-z6ckhkgg	87	4	localization	localization	NN
cord-287670-z6ckhkgg	87	5	,	,	,
cord-287670-z6ckhkgg	87	6	PRMs	prm	NNS
cord-287670-z6ckhkgg	87	7	have	have	VBP
cord-287670-z6ckhkgg	87	8	been	be	VBN
cord-287670-z6ckhkgg	87	9	divided	divide	VBN
cord-287670-z6ckhkgg	87	10	into	into	IN
cord-287670-z6ckhkgg	87	11	cellassociated	cellassociate	VBN
cord-287670-z6ckhkgg	87	12	receptors	receptor	NNS
cord-287670-z6ckhkgg	87	13	(	(	-LRB-
cord-287670-z6ckhkgg	87	14	e.g.	e.g.	RB
cord-287670-z6ckhkgg	87	15	,	,	,
cord-287670-z6ckhkgg	87	16	TLRs	TLRs	NNP
cord-287670-z6ckhkgg	87	17	)	)	-RRB-
cord-287670-z6ckhkgg	87	18	and	and	CC
cord-287670-z6ckhkgg	87	19	soluble	soluble	JJ
cord-287670-z6ckhkgg	87	20	molecules	molecule	NNS
cord-287670-z6ckhkgg	87	21	(	(	-LRB-
cord-287670-z6ckhkgg	87	22	e.g.	e.g.	RB
cord-287670-z6ckhkgg	87	23	,	,	,
cord-287670-z6ckhkgg	87	24	collectins	collectins	NNP
cord-287670-z6ckhkgg	87	25	,	,	,
cord-287670-z6ckhkgg	87	26	pentraxins	pentraxins	NNP
cord-287670-z6ckhkgg	87	27	)	)	-RRB-
cord-287670-z6ckhkgg	87	28	.	.	.
cord-287670-z6ckhkgg	88	1	Restenosis	Restenosis	NNP
cord-287670-z6ckhkgg	88	2	:	:	:
cord-287670-z6ckhkgg	89	1	common	common	JJ
cord-287670-z6ckhkgg	89	2	adverse	adverse	JJ
cord-287670-z6ckhkgg	89	3	event	event	NN
cord-287670-z6ckhkgg	89	4	in	in	IN
cord-287670-z6ckhkgg	89	5	endovascular	endovascular	JJ
cord-287670-z6ckhkgg	89	6	procedures	procedure	NNS
cord-287670-z6ckhkgg	89	7	;	;	,
cord-287670-z6ckhkgg	89	8	involves	involve	VBZ
cord-287670-z6ckhkgg	89	9	the	the	DT
cord-287670-z6ckhkgg	89	10	recurrence	recurrence	NN
cord-287670-z6ckhkgg	89	11	of	of	IN
cord-287670-z6ckhkgg	89	12	narrowing	narrowing	NN
cord-287670-z6ckhkgg	89	13	of	of	IN
cord-287670-z6ckhkgg	89	14	a	a	DT
cord-287670-z6ckhkgg	89	15	blood	blood	NN
cord-287670-z6ckhkgg	89	16	vessel	vessel	NN
cord-287670-z6ckhkgg	89	17	,	,	,
cord-287670-z6ckhkgg	89	18	usually	usually	RB
cord-287670-z6ckhkgg	89	19	an	an	DT
cord-287670-z6ckhkgg	89	20	artery	artery	NN
cord-287670-z6ckhkgg	89	21	.	.	.
cord-287670-z6ckhkgg	90	1	Toll	toll	NN
cord-287670-z6ckhkgg	90	2	-	-	HYPH
cord-287670-z6ckhkgg	90	3	like	like	JJ
cord-287670-z6ckhkgg	90	4	receptors	receptor	NNS
cord-287670-z6ckhkgg	90	5	(	(	-LRB-
cord-287670-z6ckhkgg	90	6	TLRs	TLRs	NNP
cord-287670-z6ckhkgg	90	7	)	)	-RRB-
cord-287670-z6ckhkgg	90	8	:	:	:
cord-287670-z6ckhkgg	90	9	a	a	DT
cord-287670-z6ckhkgg	90	10	family	family	NN
cord-287670-z6ckhkgg	90	11	of	of	IN
cord-287670-z6ckhkgg	90	12	PRMs	prm	NNS
cord-287670-z6ckhkgg	90	13	characterized	characterize	VBN
cord-287670-z6ckhkgg	90	14	by	by	IN
cord-287670-z6ckhkgg	90	15	an	an	DT
cord-287670-z6ckhkgg	90	16	extracellular	extracellular	JJ
cord-287670-z6ckhkgg	90	17	leucine	leucine	NN
cord-287670-z6ckhkgg	90	18	-	-	HYPH
cord-287670-z6ckhkgg	90	19	rich	rich	JJ
cord-287670-z6ckhkgg	90	20	domain	domain	NN
cord-287670-z6ckhkgg	90	21	and	and	CC
cord-287670-z6ckhkgg	90	22	a	a	DT
cord-287670-z6ckhkgg	90	23	cytoplasmic	cytoplasmic	JJ
cord-287670-z6ckhkgg	90	24	domain	domain	NN
cord-287670-z6ckhkgg	90	25	sharing	sharing	NN
cord-287670-z6ckhkgg	90	26	homology	homology	NN
cord-287670-z6ckhkgg	90	27	with	with	IN
cord-287670-z6ckhkgg	90	28	the	the	DT
cord-287670-z6ckhkgg	90	29	receptor	receptor	NN
cord-287670-z6ckhkgg	90	30	for	for	IN
cord-287670-z6ckhkgg	90	31	IL-1	IL-1	NNP
cord-287670-z6ckhkgg	90	32	and	and	CC
cord-287670-z6ckhkgg	90	33	the	the	DT
cord-287670-z6ckhkgg	90	34	toll	toll	NN
cord-287670-z6ckhkgg	90	35	protein	protein	NN
cord-287670-z6ckhkgg	90	36	of	of	IN
cord-287670-z6ckhkgg	90	37	Drosophila	Drosophila	NNP
cord-287670-z6ckhkgg	90	38	.	.	.
cord-287670-z6ckhkgg	91	1	TLRs	tlr	NNS
cord-287670-z6ckhkgg	91	2	are	be	VBP
cord-287670-z6ckhkgg	91	3	cell	cell	NN
cord-287670-z6ckhkgg	91	4	-	-	HYPH
cord-287670-z6ckhkgg	91	5	associated	associate	VBN
cord-287670-z6ckhkgg	91	6	molecules	molecule	NNS
cord-287670-z6ckhkgg	91	7	located	locate	VBN
cord-287670-z6ckhkgg	91	8	in	in	IN
cord-287670-z6ckhkgg	91	9	cytoplasmic	cytoplasmic	JJ
cord-287670-z6ckhkgg	91	10	membranes	membrane	NNS
cord-287670-z6ckhkgg	91	11	or	or	CC
cord-287670-z6ckhkgg	91	12	in	in	IN
cord-287670-z6ckhkgg	91	13	the	the	DT
cord-287670-z6ckhkgg	91	14	membranes	membrane	NNS
cord-287670-z6ckhkgg	91	15	of	of	IN
cord-287670-z6ckhkgg	91	16	endosomal	endosomal	JJ
cord-287670-z6ckhkgg	91	17	vesicles	vesicle	NNS
cord-287670-z6ckhkgg	91	18	.	.	.
cord-287670-z6ckhkgg	92	1	They	-PRON-	PRP
cord-287670-z6ckhkgg	92	2	sense	sense	VBP
cord-287670-z6ckhkgg	92	3	molecules	molecule	NNS
cord-287670-z6ckhkgg	92	4	in	in	IN
cord-287670-z6ckhkgg	92	5	extracellular	extracellular	JJ
cord-287670-z6ckhkgg	92	6	compartments	compartment	NNS
cord-287670-z6ckhkgg	92	7	and	and	CC
cord-287670-z6ckhkgg	92	8	in	in	IN
cord-287670-z6ckhkgg	92	9	the	the	DT
cord-287670-z6ckhkgg	92	10	lumen	lumen	NN
cord-287670-z6ckhkgg	92	11	of	of	IN
cord-287670-z6ckhkgg	92	12	endosomal	endosomal	NNP
cord-287670-z6ckhkgg	92	13	vesicles	vesicle	NNS
cord-287670-z6ckhkgg	92	14	.	.	.
cord-287670-z6ckhkgg	93	1	enhancer	enhancer	NN
cord-287670-z6ckhkgg	93	2	and	and	CC
cord-287670-z6ckhkgg	93	3	a	a	DT
cord-287670-z6ckhkgg	93	4	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	93	5	promoter	promoter	NN
cord-287670-z6ckhkgg	93	6	has	have	VBZ
cord-287670-z6ckhkgg	93	7	been	be	VBN
cord-287670-z6ckhkgg	93	8	deemed	deem	VBN
cord-287670-z6ckhkgg	93	9	responsible	responsible	JJ
cord-287670-z6ckhkgg	93	10	of	of	IN
cord-287670-z6ckhkgg	93	11	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	93	12	gene	gene	NN
cord-287670-z6ckhkgg	93	13	silencing	silence	VBG
cord-287670-z6ckhkgg	93	14	in	in	IN
cord-287670-z6ckhkgg	93	15	human	human	JJ
cord-287670-z6ckhkgg	93	16	colorectal	colorectal	NN
cord-287670-z6ckhkgg	93	17	and	and	CC
cord-287670-z6ckhkgg	93	18	esophageal	esophageal	JJ
cord-287670-z6ckhkgg	93	19	cancer	cancer	NN
cord-287670-z6ckhkgg	93	20	cell	cell	NN
cord-287670-z6ckhkgg	93	21	lines	line	NNS
cord-287670-z6ckhkgg	93	22	[	[	-LRB-
cord-287670-z6ckhkgg	93	23	12	12	CD
cord-287670-z6ckhkgg	93	24	]	]	-RRB-
cord-287670-z6ckhkgg	93	25	.	.	.
cord-287670-z6ckhkgg	94	1	The	the	DT
cord-287670-z6ckhkgg	94	2	protein	protein	NN
cord-287670-z6ckhkgg	94	3	is	be	VBZ
cord-287670-z6ckhkgg	94	4	a	a	DT
cord-287670-z6ckhkgg	94	5	multimer	multimer	NN
cord-287670-z6ckhkgg	94	6	with	with	IN
cord-287670-z6ckhkgg	94	7	a	a	DT
cord-287670-z6ckhkgg	94	8	complex	complex	JJ
cord-287670-z6ckhkgg	94	9	quaternary	quaternary	JJ
cord-287670-z6ckhkgg	94	10	structure	structure	NN
cord-287670-z6ckhkgg	94	11	comprising	comprise	VBG
cord-287670-z6ckhkgg	94	12	two	two	CD
cord-287670-z6ckhkgg	94	13	tetramers	tetramer	NNS
cord-287670-z6ckhkgg	94	14	linked	link	VBN
cord-287670-z6ckhkgg	94	15	by	by	IN
cord-287670-z6ckhkgg	94	16	interchain	interchain	JJ
cord-287670-z6ckhkgg	94	17	bridges	bridge	NNS
cord-287670-z6ckhkgg	94	18	to	to	TO
cord-287670-z6ckhkgg	94	19	form	form	VB
cord-287670-z6ckhkgg	94	20	an	an	DT
cord-287670-z6ckhkgg	94	21	octamer	octamer	NN
cord-287670-z6ckhkgg	94	22	of	of	IN
cord-287670-z6ckhkgg	94	23	340	340	CD
cord-287670-z6ckhkgg	94	24	kDa	kDa	NNS
cord-287670-z6ckhkgg	94	25	.	.	.
cord-287670-z6ckhkgg	95	1	The	the	DT
cord-287670-z6ckhkgg	95	2	protomer	protomer	NN
cord-287670-z6ckhkgg	95	3	comprises	comprise	VBZ
cord-287670-z6ckhkgg	95	4	381	381	CD
cord-287670-z6ckhkgg	95	5	amino	amino	NN
cord-287670-z6ckhkgg	95	6	acids	acid	NNS
cord-287670-z6ckhkgg	95	7	including	include	VBG
cord-287670-z6ckhkgg	95	8	a	a	DT
cord-287670-z6ckhkgg	95	9	17-amino	17-amino	CD
cord-287670-z6ckhkgg	95	10	-	-	HYPH
cord-287670-z6ckhkgg	95	11	acid	acid	NN
cord-287670-z6ckhkgg	95	12	signal	signal	NN
cord-287670-z6ckhkgg	95	13	peptide	peptide	NN
cord-287670-z6ckhkgg	95	14	,	,	,
cord-287670-z6ckhkgg	95	15	an	an	DT
cord-287670-z6ckhkgg	95	16	N	n	CD
cord-287670-z6ckhkgg	95	17	-	-	HYPH
cord-287670-z6ckhkgg	95	18	terminal	terminal	NN
cord-287670-z6ckhkgg	95	19	domain	domain	NN
cord-287670-z6ckhkgg	95	20	unrelated	unrelated	JJ
cord-287670-z6ckhkgg	95	21	to	to	IN
cord-287670-z6ckhkgg	95	22	any	any	DT
cord-287670-z6ckhkgg	95	23	known	know	VBN
cord-287670-z6ckhkgg	95	24	protein	protein	NN
cord-287670-z6ckhkgg	95	25	,	,	,
cord-287670-z6ckhkgg	95	26	and	and	CC
cord-287670-z6ckhkgg	95	27	a	a	DT
cord-287670-z6ckhkgg	95	28	C	c	NN
cord-287670-z6ckhkgg	95	29	-	-	HYPH
cord-287670-z6ckhkgg	95	30	terminal	terminal	NN
cord-287670-z6ckhkgg	95	31	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	95	32	domain	domain	NN
cord-287670-z6ckhkgg	95	33	homologous	homologous	JJ
cord-287670-z6ckhkgg	95	34	to	to	IN
cord-287670-z6ckhkgg	95	35	the	the	DT
cord-287670-z6ckhkgg	95	36	short	short	JJ
cord-287670-z6ckhkgg	95	37	pentraxins	pentraxin	NNS
cord-287670-z6ckhkgg	95	38	CRP	CRP	NNP
cord-287670-z6ckhkgg	95	39	and	and	CC
cord-287670-z6ckhkgg	95	40	SAP	SAP	NNP
cord-287670-z6ckhkgg	95	41	[	[	-LRB-
cord-287670-z6ckhkgg	95	42	25	25	CD
cord-287670-z6ckhkgg	95	43	]	]	-RRB-
cord-287670-z6ckhkgg	95	44	.	.	.
cord-287670-z6ckhkgg	96	1	A	a	DT
cord-287670-z6ckhkgg	96	2	single	single	JJ
cord-287670-z6ckhkgg	96	3	N	n	CD
cord-287670-z6ckhkgg	96	4	-	-	HYPH
cord-287670-z6ckhkgg	96	5	glycosylation	glycosylation	NN
cord-287670-z6ckhkgg	96	6	site	site	NN
cord-287670-z6ckhkgg	96	7	localized	localize	VBN
cord-287670-z6ckhkgg	96	8	in	in	IN
cord-287670-z6ckhkgg	96	9	the	the	DT
cord-287670-z6ckhkgg	96	10	C	c	NN
cord-287670-z6ckhkgg	96	11	-	-	HYPH
cord-287670-z6ckhkgg	96	12	terminal	terminal	NN
cord-287670-z6ckhkgg	96	13	domain	domain	NN
cord-287670-z6ckhkgg	96	14	at	at	IN
cord-287670-z6ckhkgg	96	15	Asn220	Asn220	.
cord-287670-z6ckhkgg	96	16	is	be	VBZ
cord-287670-z6ckhkgg	96	17	occupied	occupy	VBN
cord-287670-z6ckhkgg	96	18	by	by	IN
cord-287670-z6ckhkgg	96	19	corefucosylated	corefucosylated	JJ
cord-287670-z6ckhkgg	96	20	and	and	CC
cord-287670-z6ckhkgg	96	21	sialylated	sialylated	JJ
cord-287670-z6ckhkgg	96	22	complex	complex	JJ
cord-287670-z6ckhkgg	96	23	-	-	HYPH
cord-287670-z6ckhkgg	96	24	type	type	NN
cord-287670-z6ckhkgg	96	25	oligosaccharides	oligosaccharide	NNS
cord-287670-z6ckhkgg	96	26	[	[	-LRB-
cord-287670-z6ckhkgg	96	27	26	26	CD
cord-287670-z6ckhkgg	96	28	]	]	-RRB-
cord-287670-z6ckhkgg	96	29	,	,	,
cord-287670-z6ckhkgg	96	30	which	which	WDT
cord-287670-z6ckhkgg	96	31	have	have	VBP
cord-287670-z6ckhkgg	96	32	been	be	VBN
cord-287670-z6ckhkgg	96	33	shown	show	VBN
cord-287670-z6ckhkgg	96	34	to	to	TO
cord-287670-z6ckhkgg	96	35	modulate	modulate	VB
cord-287670-z6ckhkgg	96	36	the	the	DT
cord-287670-z6ckhkgg	96	37	interaction	interaction	NN
cord-287670-z6ckhkgg	96	38	of	of	IN
cord-287670-z6ckhkgg	96	39	human	human	JJ
cord-287670-z6ckhkgg	96	40	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	96	41	with	with	IN
cord-287670-z6ckhkgg	96	42	complement	complement	JJ
cord-287670-z6ckhkgg	96	43	components	component	NNS
cord-287670-z6ckhkgg	96	44	such	such	JJ
cord-287670-z6ckhkgg	96	45	as	as	IN
cord-287670-z6ckhkgg	96	46	human	human	JJ
cord-287670-z6ckhkgg	96	47	C1q	C1q	NNP
cord-287670-z6ckhkgg	96	48	[	[	-LRB-
cord-287670-z6ckhkgg	96	49	26	26	CD
cord-287670-z6ckhkgg	96	50	]	]	-RRB-
cord-287670-z6ckhkgg	96	51	,	,	,
cord-287670-z6ckhkgg	96	52	factor	factor	NN
cord-287670-z6ckhkgg	96	53	H	h	NN
cord-287670-z6ckhkgg	96	54	[	[	-LRB-
cord-287670-z6ckhkgg	96	55	27	27	CD
cord-287670-z6ckhkgg	96	56	]	]	-RRB-
cord-287670-z6ckhkgg	96	57	,	,	,
cord-287670-z6ckhkgg	96	58	and	and	CC
cord-287670-z6ckhkgg	96	59	ficolin-1	ficolin-1	NNP
cord-287670-z6ckhkgg	96	60	[	[	-LRB-
cord-287670-z6ckhkgg	96	61	28	28	CD
cord-287670-z6ckhkgg	96	62	]	]	-RRB-
cord-287670-z6ckhkgg	96	63	and	and	CC
cord-287670-z6ckhkgg	96	64	to	to	TO
cord-287670-z6ckhkgg	96	65	be	be	VB
cord-287670-z6ckhkgg	96	66	required	require	VBN
cord-287670-z6ckhkgg	96	67	for	for	IN
cord-287670-z6ckhkgg	96	68	influenza	influenza	NN
cord-287670-z6ckhkgg	96	69	virus	virus	NN
cord-287670-z6ckhkgg	96	70	recognition	recognition	NN
cord-287670-z6ckhkgg	96	71	[	[	-LRB-
cord-287670-z6ckhkgg	96	72	29	29	CD
cord-287670-z6ckhkgg	96	73	]	]	-RRB-
cord-287670-z6ckhkgg	96	74	and	and	CC
cord-287670-z6ckhkgg	96	75	binding	bind	VBG
cord-287670-z6ckhkgg	96	76	to	to	IN
cord-287670-z6ckhkgg	96	77	the	the	DT
cord-287670-z6ckhkgg	96	78	human	human	JJ
cord-287670-z6ckhkgg	96	79	and	and	CC
cord-287670-z6ckhkgg	96	80	murine	murine	JJ
cord-287670-z6ckhkgg	96	81	adhesion	adhesion	NN
cord-287670-z6ckhkgg	96	82	molecule	molecule	NN
cord-287670-z6ckhkgg	96	83	P	p	NN
cord-287670-z6ckhkgg	96	84	-	-	HYPH
cord-287670-z6ckhkgg	96	85	selectin	selectin	NNP
cord-287670-z6ckhkgg	96	86	in	in	IN
cord-287670-z6ckhkgg	96	87	vitro	vitro	FW
cord-287670-z6ckhkgg	96	88	and	and	CC
cord-287670-z6ckhkgg	96	89	in	in	IN
cord-287670-z6ckhkgg	96	90	vivo	vivo	NNP
cord-287670-z6ckhkgg	96	91	[	[	-LRB-
cord-287670-z6ckhkgg	96	92	30	30	CD
cord-287670-z6ckhkgg	96	93	]	]	-RRB-
cord-287670-z6ckhkgg	96	94	.	.	.
cord-287670-z6ckhkgg	97	1	Various	various	JJ
cord-287670-z6ckhkgg	97	2	cell	cell	NN
cord-287670-z6ckhkgg	97	3	types	type	NNS
cord-287670-z6ckhkgg	97	4	,	,	,
cord-287670-z6ckhkgg	97	5	including	include	VBG
cord-287670-z6ckhkgg	97	6	DCs	dc	NNS
cord-287670-z6ckhkgg	97	7	,	,	,
cord-287670-z6ckhkgg	97	8	monocytes	monocyte	NNS
cord-287670-z6ckhkgg	97	9	,	,	,
cord-287670-z6ckhkgg	97	10	macrophages	macrophage	NNS
cord-287670-z6ckhkgg	97	11	,	,	,
cord-287670-z6ckhkgg	97	12	epithelial	epithelial	JJ
cord-287670-z6ckhkgg	97	13	cells	cell	NNS
cord-287670-z6ckhkgg	97	14	,	,	,
cord-287670-z6ckhkgg	97	15	ECs	ec	NNS
cord-287670-z6ckhkgg	97	16	,	,	,
cord-287670-z6ckhkgg	97	17	fibroblasts	fibroblast	NNS
cord-287670-z6ckhkgg	97	18	,	,	,
cord-287670-z6ckhkgg	97	19	and	and	CC
cord-287670-z6ckhkgg	97	20	adipocytes	adipocyte	NNS
cord-287670-z6ckhkgg	97	21	,	,	,
cord-287670-z6ckhkgg	97	22	produce	produce	VBP
cord-287670-z6ckhkgg	97	23	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	97	24	on	on	IN
cord-287670-z6ckhkgg	97	25	stimulation	stimulation	NN
cord-287670-z6ckhkgg	97	26	with	with	IN
cord-287670-z6ckhkgg	97	27	inflammatory	inflammatory	JJ
cord-287670-z6ckhkgg	97	28	cytokines	cytokine	NNS
cord-287670-z6ckhkgg	97	29	(	(	-LRB-
cord-287670-z6ckhkgg	97	30	e.g.	e.g.	RB
cord-287670-z6ckhkgg	97	31	,	,	,
cord-287670-z6ckhkgg	97	32	TNF/	TNF/	NNP
cord-287670-z6ckhkgg	97	33	,	,	,
cord-287670-z6ckhkgg	97	34	IL-1b	IL-1b	NNP
cord-287670-z6ckhkgg	97	35	)	)	-RRB-
cord-287670-z6ckhkgg	97	36	,	,	,
cord-287670-z6ckhkgg	97	37	TLR	TLR	NNP
cord-287670-z6ckhkgg	97	38	agonists	agonist	NNS
cord-287670-z6ckhkgg	97	39	and	and	CC
cord-287670-z6ckhkgg	97	40	microbial	microbial	JJ
cord-287670-z6ckhkgg	97	41	moieties	moiety	NNS
cord-287670-z6ckhkgg	97	42	[	[	-LRB-
cord-287670-z6ckhkgg	97	43	e.g.	e.g.	RB
cord-287670-z6ckhkgg	97	44	,	,	,
cord-287670-z6ckhkgg	97	45	lipopolysaccharide	lipopolysaccharide	NN
cord-287670-z6ckhkgg	97	46	(	(	-LRB-
cord-287670-z6ckhkgg	97	47	LPS	LPS	NNP
cord-287670-z6ckhkgg	97	48	)	)	-RRB-
cord-287670-z6ckhkgg	97	49	,	,	,
cord-287670-z6ckhkgg	97	50	Klebsiella	Klebsiella	NNP
cord-287670-z6ckhkgg	97	51	pneumoniae	pneumoniae	NN
cord-287670-z6ckhkgg	97	52	outer	outer	JJ
cord-287670-z6ckhkgg	97	53	membrane	membrane	NN
cord-287670-z6ckhkgg	97	54	protein	protein	NN
cord-287670-z6ckhkgg	97	55	A	A	NNP
cord-287670-z6ckhkgg	97	56	(	(	-LRB-
cord-287670-z6ckhkgg	97	57	KpOmpA	KpOmpA	NNP
cord-287670-z6ckhkgg	97	58	)	)	-RRB-
cord-287670-z6ckhkgg	97	59	,	,	,
cord-287670-z6ckhkgg	97	60	other	other	JJ
cord-287670-z6ckhkgg	97	61	pathogens	pathogen	NNS
cord-287670-z6ckhkgg	97	62	such	such	JJ
cord-287670-z6ckhkgg	97	63	as	as	IN
cord-287670-z6ckhkgg	97	64	UPEC	UPEC	NNP
cord-287670-z6ckhkgg	97	65	and	and	CC
cord-287670-z6ckhkgg	97	66	fungal	fungal	JJ
cord-287670-z6ckhkgg	97	67	Aspergillus	aspergillus	NN
cord-287670-z6ckhkgg	97	68	fumigatus	fumigatus	NN
cord-287670-z6ckhkgg	97	69	]	]	-RRB-
cord-287670-z6ckhkgg	97	70	[	[	-LRB-
cord-287670-z6ckhkgg	97	71	14	14	CD
cord-287670-z6ckhkgg	97	72	]	]	-RRB-
cord-287670-z6ckhkgg	98	1	(	(	-LRB-
cord-287670-z6ckhkgg	98	2	Figure	figure	NN
cord-287670-z6ckhkgg	98	3	1	1	CD
cord-287670-z6ckhkgg	98	4	)	)	-RRB-
cord-287670-z6ckhkgg	98	5	.	.	.
cord-287670-z6ckhkgg	99	1	Neutrophils	neutrophils	NN
cord-287670-z6ckhkgg	99	2	store	store	NN
cord-287670-z6ckhkgg	99	3	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	99	4	in	in	IN
cord-287670-z6ckhkgg	99	5	specific	specific	JJ
cord-287670-z6ckhkgg	99	6	granules	granule	NNS
cord-287670-z6ckhkgg	99	7	and	and	CC
cord-287670-z6ckhkgg	99	8	rapidly	rapidly	RB
cord-287670-z6ckhkgg	99	9	release	release	VB
cord-287670-z6ckhkgg	99	10	it	-PRON-	PRP
cord-287670-z6ckhkgg	99	11	on	on	IN
cord-287670-z6ckhkgg	99	12	encounter	encounter	NN
cord-287670-z6ckhkgg	99	13	with	with	IN
cord-287670-z6ckhkgg	99	14	microorganisms	microorganism	NNS
cord-287670-z6ckhkgg	99	15	or	or	CC
cord-287670-z6ckhkgg	99	16	on	on	IN
cord-287670-z6ckhkgg	99	17	cell	cell	NN
cord-287670-z6ckhkgg	99	18	stimulation	stimulation	NN
cord-287670-z6ckhkgg	99	19	due	due	IN
cord-287670-z6ckhkgg	99	20	to	to	IN
cord-287670-z6ckhkgg	99	21	infection	infection	NN
cord-287670-z6ckhkgg	99	22	,	,	,
cord-287670-z6ckhkgg	99	23	such	such	JJ
cord-287670-z6ckhkgg	99	24	as	as	IN
cord-287670-z6ckhkgg	99	25	in	in	IN
cord-287670-z6ckhkgg	99	26	aspergillosis	aspergillosis	NNP
cord-287670-z6ckhkgg	99	27	,	,	,
cord-287670-z6ckhkgg	99	28	or	or	CC
cord-287670-z6ckhkgg	99	29	with	with	IN
cord-287670-z6ckhkgg	99	30	sterile	sterile	JJ
cord-287670-z6ckhkgg	99	31	tissue	tissue	NN
cord-287670-z6ckhkgg	99	32	damage	damage	NN
cord-287670-z6ckhkgg	99	33	,	,	,
cord-287670-z6ckhkgg	99	34	as	as	IN
cord-287670-z6ckhkgg	99	35	in	in	IN
cord-287670-z6ckhkgg	99	36	the	the	DT
cord-287670-z6ckhkgg	99	37	case	case	NN
cord-287670-z6ckhkgg	99	38	of	of	IN
cord-287670-z6ckhkgg	99	39	human	human	JJ
cord-287670-z6ckhkgg	99	40	acute	acute	JJ
cord-287670-z6ckhkgg	99	41	myocardial	myocardial	JJ
cord-287670-z6ckhkgg	99	42	infarction	infarction	NN
cord-287670-z6ckhkgg	99	43	[	[	-LRB-
cord-287670-z6ckhkgg	99	44	6	6	CD
cord-287670-z6ckhkgg	99	45	,	,	,
cord-287670-z6ckhkgg	99	46	31	31	CD
cord-287670-z6ckhkgg	99	47	]	]	-RRB-
cord-287670-z6ckhkgg	99	48	.	.	.
cord-287670-z6ckhkgg	100	1	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	100	2	Ɵssue	Ɵssue	NNP
cord-287670-z6ckhkgg	100	3	damage	damage	NN
cord-287670-z6ckhkgg	101	1	TLR	TLR	NNP
cord-287670-z6ckhkgg	101	2	agonists	agonist	NNS
cord-287670-z6ckhkgg	101	3	,	,	,
cord-287670-z6ckhkgg	101	4	inflammatory	inflammatory	JJ
cord-287670-z6ckhkgg	101	5	cytokines	cytokine	NNS
cord-287670-z6ckhkgg	101	6	(	(	-LRB-
cord-287670-z6ckhkgg	101	7	IL-1	IL-1	NNP
cord-287670-z6ckhkgg	101	8	,	,	,
cord-287670-z6ckhkgg	101	9	TNF	TNF	NNP
cord-287670-z6ckhkgg	101	10	)	)	-RRB-
cord-287670-z6ckhkgg	101	11	...	...	.
cord-287670-z6ckhkgg	102	1	mRNA	mRNA	NNP
cord-287670-z6ckhkgg	102	2	is	be	VBZ
cord-287670-z6ckhkgg	102	3	transcribed	transcribe	VBN
cord-287670-z6ckhkgg	102	4	only	only	RB
cord-287670-z6ckhkgg	102	5	in	in	IN
cord-287670-z6ckhkgg	102	6	myeloid	myeloid	JJ
cord-287670-z6ckhkgg	102	7	precursors	precursor	NNS
cord-287670-z6ckhkgg	102	8	(	(	-LRB-
cord-287670-z6ckhkgg	102	9	promyelocytes	promyelocytes	NNP
cord-287670-z6ckhkgg	102	10	and	and	CC
cord-287670-z6ckhkgg	102	11	myelocytes	myelocytes	NNPS
cord-287670-z6ckhkgg	102	12	/	/	SYM
cord-287670-z6ckhkgg	102	13	metamyelocytes	metamyelocyte	NNS
cord-287670-z6ckhkgg	102	14	)	)	-RRB-
cord-287670-z6ckhkgg	102	15	and	and	CC
cord-287670-z6ckhkgg	102	16	not	not	RB
cord-287670-z6ckhkgg	102	17	in	in	IN
cord-287670-z6ckhkgg	102	18	resting	rest	VBG
cord-287670-z6ckhkgg	102	19	mature	mature	JJ
cord-287670-z6ckhkgg	102	20	cells	cell	NNS
cord-287670-z6ckhkgg	102	21	in	in	IN
cord-287670-z6ckhkgg	102	22	mice	mouse	NNS
cord-287670-z6ckhkgg	102	23	and	and	CC
cord-287670-z6ckhkgg	102	24	humans	human	NNS
cord-287670-z6ckhkgg	102	25	[	[	-LRB-
cord-287670-z6ckhkgg	102	26	6	6	CD
cord-287670-z6ckhkgg	102	27	]	]	-RRB-
cord-287670-z6ckhkgg	102	28	.	.	.
cord-287670-z6ckhkgg	103	1	The	the	DT
cord-287670-z6ckhkgg	103	2	binding	binding	NN
cord-287670-z6ckhkgg	103	3	of	of	IN
cord-287670-z6ckhkgg	103	4	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	103	5	to	to	TO
cord-287670-z6ckhkgg	103	6	select	select	VB
cord-287670-z6ckhkgg	103	7	microorganisms	microorganism	NNS
cord-287670-z6ckhkgg	103	8	,	,	,
cord-287670-z6ckhkgg	103	9	including	include	VBG
cord-287670-z6ckhkgg	103	10	bacteria	bacteria	NNS
cord-287670-z6ckhkgg	103	11	,	,	,
cord-287670-z6ckhkgg	103	12	fungi	fungus	NNS
cord-287670-z6ckhkgg	103	13	,	,	,
cord-287670-z6ckhkgg	103	14	and	and	CC
cord-287670-z6ckhkgg	103	15	viruses	virus	NNS
cord-287670-z6ckhkgg	103	16	,	,	,
cord-287670-z6ckhkgg	103	17	leads	lead	VBZ
cord-287670-z6ckhkgg	103	18	to	to	IN
cord-287670-z6ckhkgg	103	19	the	the	DT
cord-287670-z6ckhkgg	103	20	activation	activation	NN
cord-287670-z6ckhkgg	103	21	of	of	IN
cord-287670-z6ckhkgg	103	22	various	various	JJ
cord-287670-z6ckhkgg	103	23	antimicrobial	antimicrobial	JJ
cord-287670-z6ckhkgg	103	24	effector	effector	NN
cord-287670-z6ckhkgg	103	25	mechanisms	mechanism	NNS
cord-287670-z6ckhkgg	103	26	[	[	-LRB-
cord-287670-z6ckhkgg	103	27	3	3	CD
cord-287670-z6ckhkgg	103	28	]	]	-RRB-
cord-287670-z6ckhkgg	103	29	(	(	-LRB-
cord-287670-z6ckhkgg	103	30	Figures	figure	NNS
cord-287670-z6ckhkgg	103	31	1	1	CD
cord-287670-z6ckhkgg	103	32	and	and	CC
cord-287670-z6ckhkgg	103	33	2	2	CD
cord-287670-z6ckhkgg	103	34	)	)	-RRB-
cord-287670-z6ckhkgg	103	35	.	.	.
cord-287670-z6ckhkgg	104	1	In	in	IN
cord-287670-z6ckhkgg	104	2	addition	addition	NN
cord-287670-z6ckhkgg	104	3	,	,	,
cord-287670-z6ckhkgg	104	4	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	104	5	behaves	behave	VBZ
cord-287670-z6ckhkgg	104	6	as	as	IN
cord-287670-z6ckhkgg	104	7	an	an	DT
cord-287670-z6ckhkgg	104	8	immunoregulatory	immunoregulatory	JJ
cord-287670-z6ckhkgg	104	9	molecule	molecule	NN
cord-287670-z6ckhkgg	104	10	;	;	:
cord-287670-z6ckhkgg	104	11	it	-PRON-	PRP
cord-287670-z6ckhkgg	104	12	can	can	MD
cord-287670-z6ckhkgg	104	13	interact	interact	VB
cord-287670-z6ckhkgg	104	14	with	with	IN
cord-287670-z6ckhkgg	104	15	P	p	NN
cord-287670-z6ckhkgg	104	16	-	-	HYPH
cord-287670-z6ckhkgg	104	17	selectin	selectin	NNP
cord-287670-z6ckhkgg	104	18	,	,	,
cord-287670-z6ckhkgg	104	19	which	which	WDT
cord-287670-z6ckhkgg	104	20	results	result	VBZ
cord-287670-z6ckhkgg	104	21	in	in	IN
cord-287670-z6ckhkgg	104	22	the	the	DT
cord-287670-z6ckhkgg	104	23	modulation	modulation	NN
cord-287670-z6ckhkgg	104	24	of	of	IN
cord-287670-z6ckhkgg	104	25	neutrophil	neutrophil	NN
cord-287670-z6ckhkgg	104	26	recruitment	recruitment	NN
cord-287670-z6ckhkgg	104	27	,	,	,
cord-287670-z6ckhkgg	104	28	but	but	CC
cord-287670-z6ckhkgg	104	29	it	-PRON-	PRP
cord-287670-z6ckhkgg	104	30	can	can	MD
cord-287670-z6ckhkgg	104	31	also	also	RB
cord-287670-z6ckhkgg	104	32	interact	interact	VB
cord-287670-z6ckhkgg	104	33	with	with	IN
cord-287670-z6ckhkgg	104	34	components	component	NNS
cord-287670-z6ckhkgg	104	35	of	of	IN
cord-287670-z6ckhkgg	104	36	the	the	DT
cord-287670-z6ckhkgg	104	37	complement	complement	NN
cord-287670-z6ckhkgg	104	38	cascade	cascade	NN
cord-287670-z6ckhkgg	104	39	and	and	CC
cord-287670-z6ckhkgg	104	40	tune	tune	NN
cord-287670-z6ckhkgg	104	41	complement	complement	NN
cord-287670-z6ckhkgg	104	42	activation	activation	NN
cord-287670-z6ckhkgg	104	43	[	[	-LRB-
cord-287670-z6ckhkgg	104	44	30	30	CD
cord-287670-z6ckhkgg	104	45	,	,	,
cord-287670-z6ckhkgg	104	46	32	32	CD
cord-287670-z6ckhkgg	104	47	]	]	-RRB-
cord-287670-z6ckhkgg	104	48	.	.	.
cord-287670-z6ckhkgg	105	1	During	during	IN
cord-287670-z6ckhkgg	105	2	infection	infection	NN
cord-287670-z6ckhkgg	105	3	,	,	,
cord-287670-z6ckhkgg	105	4	such	such	JJ
cord-287670-z6ckhkgg	105	5	as	as	IN
cord-287670-z6ckhkgg	105	6	in	in	IN
cord-287670-z6ckhkgg	105	7	the	the	DT
cord-287670-z6ckhkgg	105	8	case	case	NN
cord-287670-z6ckhkgg	105	9	of	of	IN
cord-287670-z6ckhkgg	105	10	human	human	JJ
cord-287670-z6ckhkgg	105	11	sepsis	sepsis	NN
cord-287670-z6ckhkgg	105	12	,	,	,
cord-287670-z6ckhkgg	105	13	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	105	14	blood	blood	NN
cord-287670-z6ckhkgg	105	15	levels	level	NNS
cord-287670-z6ckhkgg	105	16	rapidly	rapidly	RB
cord-287670-z6ckhkgg	105	17	increase	increase	VBP
cord-287670-z6ckhkgg	105	18	from	from	IN
cord-287670-z6ckhkgg	105	19	approximately	approximately	RB
cord-287670-z6ckhkgg	105	20	2	2	CD
cord-287670-z6ckhkgg	105	21	ng	ng	NN
cord-287670-z6ckhkgg	105	22	/	/	SYM
cord-287670-z6ckhkgg	105	23	ml	ml	NN
cord-287670-z6ckhkgg	105	24	to	to	IN
cord-287670-z6ckhkgg	105	25	200	200	CD
cord-287670-z6ckhkgg	105	26	-	-	HYPH
cord-287670-z6ckhkgg	105	27	800	800	CD
cord-287670-z6ckhkgg	105	28	ng	ng	NN
cord-287670-z6ckhkgg	105	29	/	/	SYM
cord-287670-z6ckhkgg	105	30	ml	ml	NN
cord-287670-z6ckhkgg	105	31	,	,	,
cord-287670-z6ckhkgg	105	32	correlating	correlate	VBG
cord-287670-z6ckhkgg	105	33	with	with	IN
cord-287670-z6ckhkgg	105	34	both	both	DT
cord-287670-z6ckhkgg	105	35	infection	infection	NN
cord-287670-z6ckhkgg	105	36	and	and	CC
cord-287670-z6ckhkgg	105	37	disease	disease	NN
cord-287670-z6ckhkgg	105	38	severity	severity	NN
cord-287670-z6ckhkgg	105	39	and	and	CC
cord-287670-z6ckhkgg	105	40	predicting	predict	VBG
cord-287670-z6ckhkgg	105	41	patient	patient	JJ
cord-287670-z6ckhkgg	105	42	survival	survival	NN
cord-287670-z6ckhkgg	105	43	[	[	-LRB-
cord-287670-z6ckhkgg	105	44	16	16	CD
cord-287670-z6ckhkgg	105	45	,	,	,
cord-287670-z6ckhkgg	105	46	[	[	-LRB-
cord-287670-z6ckhkgg	105	47	33	33	CD
cord-287670-z6ckhkgg	105	48	]	]	-RRB-
cord-287670-z6ckhkgg	105	49	[	[	-LRB-
cord-287670-z6ckhkgg	105	50	34	34	CD
cord-287670-z6ckhkgg	105	51	]	]	-RRB-
cord-287670-z6ckhkgg	105	52	[	[	-LRB-
cord-287670-z6ckhkgg	105	53	35	35	CD
cord-287670-z6ckhkgg	105	54	]	]	-RRB-
cord-287670-z6ckhkgg	105	55	[	[	-LRB-
cord-287670-z6ckhkgg	105	56	36	36	CD
cord-287670-z6ckhkgg	105	57	]	]	-RRB-
cord-287670-z6ckhkgg	106	1	(	(	-LRB-
cord-287670-z6ckhkgg	106	2	Figure	figure	NN
cord-287670-z6ckhkgg	106	3	1	1	CD
cord-287670-z6ckhkgg	106	4	)	)	-RRB-
cord-287670-z6ckhkgg	106	5	.	.	.
cord-287670-z6ckhkgg	107	1	Importantly	importantly	RB
cord-287670-z6ckhkgg	107	2	,	,	,
cord-287670-z6ckhkgg	107	3	although	although	IN
cord-287670-z6ckhkgg	107	4	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	107	5	has	have	VBZ
cord-287670-z6ckhkgg	107	6	long	long	RB
cord-287670-z6ckhkgg	107	7	been	be	VBN
cord-287670-z6ckhkgg	107	8	demonstrated	demonstrate	VBN
cord-287670-z6ckhkgg	107	9	to	to	TO
cord-287670-z6ckhkgg	107	10	exert	exert	VB
cord-287670-z6ckhkgg	107	11	a	a	DT
cord-287670-z6ckhkgg	107	12	protective	protective	JJ
cord-287670-z6ckhkgg	107	13	role	role	NN
cord-287670-z6ckhkgg	107	14	during	during	IN
cord-287670-z6ckhkgg	107	15	microbial	microbial	JJ
cord-287670-z6ckhkgg	107	16	infections	infection	NNS
cord-287670-z6ckhkgg	107	17	,	,	,
cord-287670-z6ckhkgg	107	18	it	-PRON-	PRP
cord-287670-z6ckhkgg	107	19	has	have	VBZ
cord-287670-z6ckhkgg	107	20	now	now	RB
cord-287670-z6ckhkgg	107	21	emerged	emerge	VBN
cord-287670-z6ckhkgg	107	22	as	as	IN
cord-287670-z6ckhkgg	107	23	a	a	DT
cord-287670-z6ckhkgg	107	24	potential	potential	JJ
cord-287670-z6ckhkgg	107	25	player	player	NN
cord-287670-z6ckhkgg	107	26	in	in	IN
cord-287670-z6ckhkgg	107	27	contributing	contribute	VBG
cord-287670-z6ckhkgg	107	28	to	to	IN
cord-287670-z6ckhkgg	107	29	immunopathology	immunopathology	NN
cord-287670-z6ckhkgg	107	30	under	under	IN
cord-287670-z6ckhkgg	107	31	specific	specific	JJ
cord-287670-z6ckhkgg	107	32	circumstances	circumstance	NNS
cord-287670-z6ckhkgg	107	33	.	.	.
cord-287670-z6ckhkgg	108	1	For	for	IN
cord-287670-z6ckhkgg	108	2	instance	instance	NN
cord-287670-z6ckhkgg	108	3	,	,	,
cord-287670-z6ckhkgg	108	4	in	in	IN
cord-287670-z6ckhkgg	108	5	vitro	vitro	FW
cord-287670-z6ckhkgg	108	6	specific	specific	JJ
cord-287670-z6ckhkgg	108	7	binding	binding	NN
cord-287670-z6ckhkgg	108	8	of	of	IN
cord-287670-z6ckhkgg	108	9	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	108	10	to	to	TO
cord-287670-z6ckhkgg	108	11	fungal	fungal	VB
cord-287670-z6ckhkgg	108	12	components	component	NNS
cord-287670-z6ckhkgg	108	13	has	have	VBZ
cord-287670-z6ckhkgg	108	14	been	be	VBN
cord-287670-z6ckhkgg	108	15	observed	observe	VBN
cord-287670-z6ckhkgg	108	16	for	for	IN
cord-287670-z6ckhkgg	108	17	A.	a.	NN
cord-287670-z6ckhkgg	108	18	fumigatus	fumigatus	NNP
cord-287670-z6ckhkgg	108	19	[	[	-LRB-
cord-287670-z6ckhkgg	108	20	37	37	CD
cord-287670-z6ckhkgg	108	21	]	]	-RRB-
cord-287670-z6ckhkgg	108	22	,	,	,
cord-287670-z6ckhkgg	108	23	Paracoccidioides	Paracoccidioides	NNP
cord-287670-z6ckhkgg	108	24	brasiliensis	brasiliensis	NN
cord-287670-z6ckhkgg	108	25	,	,	,
cord-287670-z6ckhkgg	108	26	and	and	CC
cord-287670-z6ckhkgg	108	27	zymosan	zymosan	NNP
cord-287670-z6ckhkgg	108	28	[	[	-LRB-
cord-287670-z6ckhkgg	108	29	38	38	CD
cord-287670-z6ckhkgg	108	30	]	]	-RRB-
cord-287670-z6ckhkgg	108	31	.	.	.
cord-287670-z6ckhkgg	109	1	In	in	IN
cord-287670-z6ckhkgg	109	2	particular	particular	JJ
cord-287670-z6ckhkgg	109	3	,	,	,
cord-287670-z6ckhkgg	109	4	in	in	IN
cord-287670-z6ckhkgg	109	5	vivo	vivo	NNP
cord-287670-z6ckhkgg	109	6	studies	study	NNS
cord-287670-z6ckhkgg	109	7	have	have	VBP
cord-287670-z6ckhkgg	109	8	revealed	reveal	VBN
cord-287670-z6ckhkgg	109	9	that	that	IN
cord-287670-z6ckhkgg	109	10	global	global	JJ
cord-287670-z6ckhkgg	109	11	PTX3-deficient	PTX3-deficient	NNP
cord-287670-z6ckhkgg	109	12	mice	mouse	NNS
cord-287670-z6ckhkgg	109	13	are	be	VBP
cord-287670-z6ckhkgg	109	14	more	more	RBR
cord-287670-z6ckhkgg	109	15	susceptible	susceptible	JJ
cord-287670-z6ckhkgg	109	16	to	to	IN
cord-287670-z6ckhkgg	109	17	A.	a.	NN
cord-287670-z6ckhkgg	109	18	fumigatus	fumigatus	NN
cord-287670-z6ckhkgg	109	19	infection	infection	NN
cord-287670-z6ckhkgg	109	20	due	due	IN
cord-287670-z6ckhkgg	109	21	to	to	IN
cord-287670-z6ckhkgg	109	22	defective	defective	JJ
cord-287670-z6ckhkgg	109	23	recognition	recognition	NN
cord-287670-z6ckhkgg	109	24	of	of	IN
cord-287670-z6ckhkgg	109	25	conidia	conidium	NNS
cord-287670-z6ckhkgg	109	26	by	by	IN
cord-287670-z6ckhkgg	109	27	alveolar	alveolar	JJ
cord-287670-z6ckhkgg	109	28	macrophages	macrophage	NNS
cord-287670-z6ckhkgg	109	29	and	and	CC
cord-287670-z6ckhkgg	109	30	DCs	dc	NNS
cord-287670-z6ckhkgg	109	31	and	and	CC
cord-287670-z6ckhkgg	109	32	to	to	IN
cord-287670-z6ckhkgg	109	33	the	the	DT
cord-287670-z6ckhkgg	109	34	induction	induction	NN
cord-287670-z6ckhkgg	109	35	of	of	IN
cord-287670-z6ckhkgg	109	36	an	an	DT
cord-287670-z6ckhkgg	109	37	impaired	impaired	JJ
cord-287670-z6ckhkgg	109	38	T	t	NN
cord-287670-z6ckhkgg	109	39	helper	helper	NN
cord-287670-z6ckhkgg	109	40	(	(	-LRB-
cord-287670-z6ckhkgg	109	41	Th	Th	NNP
cord-287670-z6ckhkgg	109	42	)	)	-RRB-
cord-287670-z6ckhkgg	109	43	1	1	CD
cord-287670-z6ckhkgg	109	44	lymphocyte	lymphocyte	NN
cord-287670-z6ckhkgg	109	45	response	response	NN
cord-287670-z6ckhkgg	109	46	[	[	-LRB-
cord-287670-z6ckhkgg	109	47	37	37	CD
cord-287670-z6ckhkgg	109	48	]	]	-RRB-
cord-287670-z6ckhkgg	109	49	.	.	.
cord-287670-z6ckhkgg	110	1	Intravenous	Intravenous	NNP
cord-287670-z6ckhkgg	110	2	(	(	-LRB-
cord-287670-z6ckhkgg	110	3	i.v	i.v	NNP
cord-287670-z6ckhkgg	110	4	.	.	NNP
cord-287670-z6ckhkgg	110	5	)	)	-RRB-
cord-287670-z6ckhkgg	110	6	or	or	CC
cord-287670-z6ckhkgg	110	7	intraperitoneal	intraperitoneal	JJ
cord-287670-z6ckhkgg	110	8	(	(	-LRB-
cord-287670-z6ckhkgg	110	9	i.p	i.p	NNP
cord-287670-z6ckhkgg	110	10	.	.	NNP
cord-287670-z6ckhkgg	110	11	)	)	-RRB-
cord-287670-z6ckhkgg	110	12	treatment	treatment	NN
cord-287670-z6ckhkgg	110	13	with	with	IN
cord-287670-z6ckhkgg	110	14	recombinant	recombinant	JJ
cord-287670-z6ckhkgg	110	15	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	110	16	alone	alone	RB
cord-287670-z6ckhkgg	110	17	or	or	CC
cord-287670-z6ckhkgg	110	18	in	in	IN
cord-287670-z6ckhkgg	110	19	combination	combination	NN
cord-287670-z6ckhkgg	110	20	with	with	IN
cord-287670-z6ckhkgg	110	21	antifungal	antifungal	JJ
cord-287670-z6ckhkgg	110	22	agents	agent	NNS
cord-287670-z6ckhkgg	110	23	such	such	JJ
cord-287670-z6ckhkgg	110	24	as	as	IN
cord-287670-z6ckhkgg	110	25	amphotericin	amphotericin	NNS
cord-287670-z6ckhkgg	110	26	B	B	NNP
cord-287670-z6ckhkgg	110	27	or	or	CC
cord-287670-z6ckhkgg	110	28	voriconazole	voriconazole	NNP
cord-287670-z6ckhkgg	110	29	has	have	VBZ
cord-287670-z6ckhkgg	110	30	resulted	result	VBN
cord-287670-z6ckhkgg	110	31	in	in	IN
cord-287670-z6ckhkgg	110	32	therapeutic	therapeutic	JJ
cord-287670-z6ckhkgg	110	33	outcomes	outcome	NNS
cord-287670-z6ckhkgg	110	34	such	such	JJ
cord-287670-z6ckhkgg	110	35	as	as	IN
cord-287670-z6ckhkgg	110	36	the	the	DT
cord-287670-z6ckhkgg	110	37	reduction	reduction	NN
cord-287670-z6ckhkgg	110	38	of	of	IN
cord-287670-z6ckhkgg	110	39	fungal	fungal	JJ
cord-287670-z6ckhkgg	110	40	burden	burden	NN
cord-287670-z6ckhkgg	110	41	in	in	IN
cord-287670-z6ckhkgg	110	42	murine	murine	NN
cord-287670-z6ckhkgg	110	43	and	and	CC
cord-287670-z6ckhkgg	110	44	rat	rat	NN
cord-287670-z6ckhkgg	110	45	models	model	NNS
cord-287670-z6ckhkgg	110	46	of	of	IN
cord-287670-z6ckhkgg	110	47	pulmonary	pulmonary	JJ
cord-287670-z6ckhkgg	110	48	aspergillosis	aspergillosis	NN
cord-287670-z6ckhkgg	110	49	[	[	-LRB-
cord-287670-z6ckhkgg	110	50	6	6	CD
cord-287670-z6ckhkgg	110	51	,	,	,
cord-287670-z6ckhkgg	110	52	37	37	CD
cord-287670-z6ckhkgg	110	53	,	,	,
cord-287670-z6ckhkgg	110	54	39	39	CD
cord-287670-z6ckhkgg	110	55	,	,	,
cord-287670-z6ckhkgg	110	56	40	40	CD
cord-287670-z6ckhkgg	110	57	]	]	-RRB-
cord-287670-z6ckhkgg	110	58	and	and	CC
cord-287670-z6ckhkgg	110	59	by	by	IN
cord-287670-z6ckhkgg	110	60	favoring	favor	VBG
cord-287670-z6ckhkgg	110	61	phagocytosis	phagocytosis	NN
cord-287670-z6ckhkgg	110	62	.	.	.
cord-287670-z6ckhkgg	111	1	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	111	2	is	be	VBZ
cord-287670-z6ckhkgg	111	3	stored	store	VBN
cord-287670-z6ckhkgg	111	4	in	in	IN
cord-287670-z6ckhkgg	111	5	neutrophil	neutrophil	NN
cord-287670-z6ckhkgg	111	6	granules	granule	NNS
cord-287670-z6ckhkgg	111	7	and	and	CC
cord-287670-z6ckhkgg	111	8	in	in	IN
cord-287670-z6ckhkgg	111	9	response	response	NN
cord-287670-z6ckhkgg	111	10	to	to	IN
cord-287670-z6ckhkgg	111	11	microbial	microbial	JJ
cord-287670-z6ckhkgg	111	12	recognition	recognition	NN
cord-287670-z6ckhkgg	111	13	has	have	VBZ
cord-287670-z6ckhkgg	111	14	been	be	VBN
cord-287670-z6ckhkgg	111	15	found	find	VBN
cord-287670-z6ckhkgg	111	16	in	in	IN
cord-287670-z6ckhkgg	111	17	human	human	JJ
cord-287670-z6ckhkgg	111	18	neutrophil	neutrophil	NN
cord-287670-z6ckhkgg	111	19	extracellular	extracellular	JJ
cord-287670-z6ckhkgg	111	20	traps	trap	NNS
cord-287670-z6ckhkgg	111	21	(	(	-LRB-
cord-287670-z6ckhkgg	111	22	NETs	NETs	NNP
cord-287670-z6ckhkgg	111	23	)	)	-RRB-
cord-287670-z6ckhkgg	111	24	,	,	,
cord-287670-z6ckhkgg	111	25	suggesting	suggest	VBG
cord-287670-z6ckhkgg	111	26	that	that	IN
cord-287670-z6ckhkgg	111	27	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	111	28	is	be	VBZ
cord-287670-z6ckhkgg	111	29	involved	involve	VBN
cord-287670-z6ckhkgg	111	30	in	in	IN
cord-287670-z6ckhkgg	111	31	the	the	DT
cord-287670-z6ckhkgg	111	32	antimicrobial	antimicrobial	JJ
cord-287670-z6ckhkgg	111	33	activity	activity	NN
cord-287670-z6ckhkgg	111	34	of	of	IN
cord-287670-z6ckhkgg	111	35	NETs	net	NNS
cord-287670-z6ckhkgg	111	36	[	[	-LRB-
cord-287670-z6ckhkgg	111	37	6	6	CD
cord-287670-z6ckhkgg	111	38	]	]	-RRB-
cord-287670-z6ckhkgg	111	39	.	.	.
cord-287670-z6ckhkgg	112	1	In	in	IN
cord-287670-z6ckhkgg	112	2	this	this	DT
cord-287670-z6ckhkgg	112	3	same	same	JJ
cord-287670-z6ckhkgg	112	4	study	study	NN
cord-287670-z6ckhkgg	112	5	,	,	,
cord-287670-z6ckhkgg	112	6	the	the	DT
cord-287670-z6ckhkgg	112	7	recognition	recognition	NN
cord-287670-z6ckhkgg	112	8	and	and	CC
cord-287670-z6ckhkgg	112	9	elimination	elimination	NN
cord-287670-z6ckhkgg	112	10	of	of	IN
cord-287670-z6ckhkgg	112	11	A.	a.	NN
cord-287670-z6ckhkgg	112	12	fumigatus	fumigatus	NN
cord-287670-z6ckhkgg	112	13	conidia	conidium	NNS
cord-287670-z6ckhkgg	112	14	by	by	IN
cord-287670-z6ckhkgg	112	15	PTX3-deficient	ptx3-deficient	JJ
cord-287670-z6ckhkgg	112	16	neutrophils	neutrophil	NNS
cord-287670-z6ckhkgg	112	17	was	be	VBD
cord-287670-z6ckhkgg	112	18	poorly	poorly	RB
cord-287670-z6ckhkgg	112	19	efficient	efficient	JJ
cord-287670-z6ckhkgg	112	20	,	,	,
cord-287670-z6ckhkgg	112	21	but	but	CC
cord-287670-z6ckhkgg	112	22	opsonization	opsonization	NN
cord-287670-z6ckhkgg	112	23	of	of	IN
cord-287670-z6ckhkgg	112	24	conidia	conidium	NNS
cord-287670-z6ckhkgg	112	25	by	by	IN
cord-287670-z6ckhkgg	112	26	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	112	27	reversed	reverse	VBD
cord-287670-z6ckhkgg	112	28	this	this	DT
cord-287670-z6ckhkgg	112	29	phenotype	phenotype	NN
cord-287670-z6ckhkgg	112	30	[	[	-LRB-
cord-287670-z6ckhkgg	112	31	6	6	CD
cord-287670-z6ckhkgg	112	32	,	,	,
cord-287670-z6ckhkgg	112	33	39	39	CD
cord-287670-z6ckhkgg	112	34	]	]	-RRB-
cord-287670-z6ckhkgg	112	35	.	.	.
cord-287670-z6ckhkgg	113	1	Furthermore	furthermore	RB
cord-287670-z6ckhkgg	113	2	,	,	,
cord-287670-z6ckhkgg	113	3	neutrophil	neutrophil	NN
cord-287670-z6ckhkgg	113	4	adoptive	adoptive	JJ
cord-287670-z6ckhkgg	113	5	transfer	transfer	NN
cord-287670-z6ckhkgg	113	6	protected	protect	VBN
cord-287670-z6ckhkgg	113	7	PTX3-deficient	PTX3-deficient	NNP
cord-287670-z6ckhkgg	113	8	mice	mouse	NNS
cord-287670-z6ckhkgg	113	9	from	from	IN
cord-287670-z6ckhkgg	113	10	aspergillosis	aspergillosis	NN
cord-287670-z6ckhkgg	113	11	and	and	CC
cord-287670-z6ckhkgg	113	12	reduced	reduced	JJ
cord-287670-z6ckhkgg	113	13	fungal	fungal	JJ
cord-287670-z6ckhkgg	113	14	burden	burden	NN
cord-287670-z6ckhkgg	113	15	,	,	,
cord-287670-z6ckhkgg	113	16	revealing	reveal	VBG
cord-287670-z6ckhkgg	113	17	that	that	IN
cord-287670-z6ckhkgg	113	18	neutrophil	neutrophil	NN
cord-287670-z6ckhkgg	113	19	-	-	HYPH
cord-287670-z6ckhkgg	113	20	associated	associate	VBN
cord-287670-z6ckhkgg	113	21	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	113	22	exerted	exert	VBD
cord-287670-z6ckhkgg	113	23	major	major	JJ
cord-287670-z6ckhkgg	113	24	control	control	NN
cord-287670-z6ckhkgg	113	25	of	of	IN
cord-287670-z6ckhkgg	113	26	A.	a.	NN
cord-287670-z6ckhkgg	113	27	fumigatus	fumigatus	NN
cord-287670-z6ckhkgg	113	28	infection	infection	NN
cord-287670-z6ckhkgg	113	29	[	[	-LRB-
cord-287670-z6ckhkgg	113	30	6	6	CD
cord-287670-z6ckhkgg	113	31	]	]	-RRB-
cord-287670-z6ckhkgg	113	32	.	.	.
cord-287670-z6ckhkgg	114	1	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	114	2	has	have	VBZ
cord-287670-z6ckhkgg	114	3	also	also	RB
cord-287670-z6ckhkgg	114	4	been	be	VBN
cord-287670-z6ckhkgg	114	5	reported	report	VBN
cord-287670-z6ckhkgg	114	6	to	to	TO
cord-287670-z6ckhkgg	114	7	increase	increase	VB
cord-287670-z6ckhkgg	114	8	recognition	recognition	NN
cord-287670-z6ckhkgg	114	9	and	and	CC
cord-287670-z6ckhkgg	114	10	phagocytosis	phagocytosis	NN
cord-287670-z6ckhkgg	114	11	of	of	IN
cord-287670-z6ckhkgg	114	12	microbes	microbe	NNS
cord-287670-z6ckhkgg	114	13	in	in	IN
cord-287670-z6ckhkgg	114	14	an	an	DT
cord-287670-z6ckhkgg	114	15	FcgRIIand	fcgriiand	NN
cord-287670-z6ckhkgg	114	16	complement	complement	NN
cord-287670-z6ckhkgg	114	17	-	-	HYPH
cord-287670-z6ckhkgg	114	18	dependent	dependent	JJ
cord-287670-z6ckhkgg	114	19	manner	manner	NN
cord-287670-z6ckhkgg	114	20	,	,	,
cord-287670-z6ckhkgg	114	21	as	as	IN
cord-287670-z6ckhkgg	114	22	evidenced	evidence	VBN
cord-287670-z6ckhkgg	114	23	from	from	IN
cord-287670-z6ckhkgg	114	24	studies	study	NNS
cord-287670-z6ckhkgg	114	25	with	with	IN
cord-287670-z6ckhkgg	114	26	C1q-	C1q-	NNP
cord-287670-z6ckhkgg	114	27	,	,	,
cord-287670-z6ckhkgg	114	28	C3-	c3-	XX
cord-287670-z6ckhkgg	114	29	,	,	,
cord-287670-z6ckhkgg	114	30	and	and	CC
cord-287670-z6ckhkgg	114	31	FcgRdeficient	FcgRdeficient	NNP
cord-287670-z6ckhkgg	114	32	mice	mouse	NNS
cord-287670-z6ckhkgg	114	33	that	that	WDT
cord-287670-z6ckhkgg	114	34	displayed	display	VBD
cord-287670-z6ckhkgg	114	35	impaired	impaired	JJ
cord-287670-z6ckhkgg	114	36	phagocytosis	phagocytosis	NN
cord-287670-z6ckhkgg	114	37	of	of	IN
cord-287670-z6ckhkgg	114	38	conidia	conidium	NNS
cord-287670-z6ckhkgg	114	39	[	[	-LRB-
cord-287670-z6ckhkgg	114	40	39	39	CD
cord-287670-z6ckhkgg	114	41	]	]	-RRB-
cord-287670-z6ckhkgg	114	42	.	.	.
cord-287670-z6ckhkgg	115	1	In	in	IN
cord-287670-z6ckhkgg	115	2	particular	particular	JJ
cord-287670-z6ckhkgg	115	3	,	,	,
cord-287670-z6ckhkgg	115	4	the	the	DT
cord-287670-z6ckhkgg	115	5	binding	binding	NN
cord-287670-z6ckhkgg	115	6	of	of	IN
cord-287670-z6ckhkgg	115	7	PTX3-opsonized	ptx3-opsonized	JJ
cord-287670-z6ckhkgg	115	8	conidia	conidium	NNS
cord-287670-z6ckhkgg	115	9	to	to	IN
cord-287670-z6ckhkgg	115	10	FcgRII	FcgRII	NNP
cord-287670-z6ckhkgg	115	11	(	(	-LRB-
cord-287670-z6ckhkgg	115	12	which	which	WDT
cord-287670-z6ckhkgg	115	13	acts	act	VBZ
cord-287670-z6ckhkgg	115	14	as	as	IN
cord-287670-z6ckhkgg	115	15	a	a	DT
cord-287670-z6ckhkgg	115	16	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	115	17	receptor	receptor	NN
cord-287670-z6ckhkgg	115	18	)	)	-RRB-
cord-287670-z6ckhkgg	115	19	[	[	-LRB-
cord-287670-z6ckhkgg	115	20	20	20	CD
cord-287670-z6ckhkgg	115	21	]	]	-RRB-
cord-287670-z6ckhkgg	115	22	induced	induce	VBN
cord-287670-z6ckhkgg	115	23	inside	inside	IN
cord-287670-z6ckhkgg	115	24	-	-	HYPH
cord-287670-z6ckhkgg	115	25	out	out	NN
cord-287670-z6ckhkgg	115	26	activation	activation	NN
cord-287670-z6ckhkgg	115	27	of	of	IN
cord-287670-z6ckhkgg	115	28	CD11b	CD11b	NNS
cord-287670-z6ckhkgg	115	29	,	,	,
cord-287670-z6ckhkgg	115	30	resulting	result	VBG
cord-287670-z6ckhkgg	115	31	in	in	IN
cord-287670-z6ckhkgg	115	32	facilitated	facilitate	VBN
cord-287670-z6ckhkgg	115	33	phagocytosis	phagocytosis	NN
cord-287670-z6ckhkgg	115	34	of	of	IN
cord-287670-z6ckhkgg	115	35	C3b	c3b	NN
cord-287670-z6ckhkgg	115	36	-	-	HYPH
cord-287670-z6ckhkgg	115	37	opsonized	opsonize	VBN
cord-287670-z6ckhkgg	115	38	conidia	conidium	NNS
cord-287670-z6ckhkgg	115	39	by	by	IN
cord-287670-z6ckhkgg	115	40	human	human	JJ
cord-287670-z6ckhkgg	115	41	neutrophils	neutrophil	NNS
cord-287670-z6ckhkgg	115	42	[	[	-LRB-
cord-287670-z6ckhkgg	115	43	39	39	CD
cord-287670-z6ckhkgg	115	44	]	]	-RRB-
cord-287670-z6ckhkgg	115	45	.	.	.
cord-287670-z6ckhkgg	116	1	In	in	IN
cord-287670-z6ckhkgg	116	2	addition	addition	NN
cord-287670-z6ckhkgg	116	3	,	,	,
cord-287670-z6ckhkgg	116	4	other	other	JJ
cord-287670-z6ckhkgg	116	5	in	in	IN
cord-287670-z6ckhkgg	116	6	vitro	vitro	FW
cord-287670-z6ckhkgg	116	7	studies	study	NNS
cord-287670-z6ckhkgg	116	8	have	have	VBP
cord-287670-z6ckhkgg	116	9	also	also	RB
cord-287670-z6ckhkgg	116	10	shown	show	VBN
cord-287670-z6ckhkgg	116	11	that	that	IN
cord-287670-z6ckhkgg	116	12	the	the	DT
cord-287670-z6ckhkgg	116	13	interaction	interaction	NN
cord-287670-z6ckhkgg	116	14	and	and	CC
cord-287670-z6ckhkgg	116	15	heterocomplex	heterocomplex	NN
cord-287670-z6ckhkgg	116	16	formation	formation	NN
cord-287670-z6ckhkgg	116	17	of	of	IN
cord-287670-z6ckhkgg	116	18	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	116	19	with	with	IN
cord-287670-z6ckhkgg	116	20	ficolin-2	ficolin-2	NNP
cord-287670-z6ckhkgg	116	21	,	,	,
cord-287670-z6ckhkgg	116	22	and	and	CC
cord-287670-z6ckhkgg	116	23	,	,	,
cord-287670-z6ckhkgg	116	24	of	of	IN
cord-287670-z6ckhkgg	116	25	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	116	26	with	with	IN
cord-287670-z6ckhkgg	116	27	mannose	mannose	NN
cord-287670-z6ckhkgg	116	28	-	-	HYPH
cord-287670-z6ckhkgg	116	29	binding	bind	VBG
cord-287670-z6ckhkgg	116	30	lectin	lectin	NN
cord-287670-z6ckhkgg	116	31	(	(	-LRB-
cord-287670-z6ckhkgg	116	32	MBL	MBL	NNP
cord-287670-z6ckhkgg	116	33	)	)	-RRB-
cord-287670-z6ckhkgg	116	34	on	on	IN
cord-287670-z6ckhkgg	116	35	fungal	fungal	JJ
cord-287670-z6ckhkgg	116	36	surfaces	surface	NNS
cord-287670-z6ckhkgg	116	37	,	,	,
cord-287670-z6ckhkgg	116	38	could	could	MD
cord-287670-z6ckhkgg	116	39	increase	increase	VB
cord-287670-z6ckhkgg	116	40	complement	complement	JJ
cord-287670-z6ckhkgg	116	41	deposition	deposition	NN
cord-287670-z6ckhkgg	116	42	on	on	IN
cord-287670-z6ckhkgg	116	43	the	the	DT
cord-287670-z6ckhkgg	116	44	same	same	JJ
cord-287670-z6ckhkgg	116	45	surfaces	surface	NNS
cord-287670-z6ckhkgg	116	46	of	of	IN
cord-287670-z6ckhkgg	116	47	A.	a.	NN
cord-287670-z6ckhkgg	116	48	fumigatus	fumigatus	NN
cord-287670-z6ckhkgg	116	49	and	and	CC
cord-287670-z6ckhkgg	116	50	Candida	Candida	NNP
cord-287670-z6ckhkgg	116	51	albicans	albican	NNS
cord-287670-z6ckhkgg	116	52	,	,	,
cord-287670-z6ckhkgg	116	53	respectively	respectively	RB
cord-287670-z6ckhkgg	116	54	[	[	-LRB-
cord-287670-z6ckhkgg	116	55	41	41	CD
cord-287670-z6ckhkgg	116	56	,	,	,
cord-287670-z6ckhkgg	116	57	42	42	CD
cord-287670-z6ckhkgg	116	58	]	]	-RRB-
cord-287670-z6ckhkgg	116	59	.	.	.
cord-287670-z6ckhkgg	117	1	Zymosan	Zymosan	NNP
cord-287670-z6ckhkgg	117	2	has	have	VBZ
cord-287670-z6ckhkgg	117	3	also	also	RB
cord-287670-z6ckhkgg	117	4	been	be	VBN
cord-287670-z6ckhkgg	117	5	shown	show	VBN
cord-287670-z6ckhkgg	117	6	to	to	TO
cord-287670-z6ckhkgg	117	7	induce	induce	VB
cord-287670-z6ckhkgg	117	8	the	the	DT
cord-287670-z6ckhkgg	117	9	expression	expression	NN
cord-287670-z6ckhkgg	117	10	of	of	IN
cord-287670-z6ckhkgg	117	11	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	117	12	in	in	IN
cord-287670-z6ckhkgg	117	13	mouse	mouse	NN
cord-287670-z6ckhkgg	117	14	peritoneal	peritoneal	JJ
cord-287670-z6ckhkgg	117	15	macrophages	macrophage	NNS
cord-287670-z6ckhkgg	117	16	in	in	IN
cord-287670-z6ckhkgg	117	17	vitro	vitro	FW
cord-287670-z6ckhkgg	117	18	[	[	-LRB-
cord-287670-z6ckhkgg	117	19	38	38	CD
cord-287670-z6ckhkgg	117	20	]	]	-RRB-
cord-287670-z6ckhkgg	117	21	.	.	.
cord-287670-z6ckhkgg	118	1	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	118	2	,	,	,
cord-287670-z6ckhkgg	118	3	in	in	IN
cord-287670-z6ckhkgg	118	4	turn	turn	NN
cord-287670-z6ckhkgg	118	5	,	,	,
cord-287670-z6ckhkgg	118	6	by	by	IN
cord-287670-z6ckhkgg	118	7	binding	bind	VBG
cord-287670-z6ckhkgg	118	8	to	to	IN
cord-287670-z6ckhkgg	118	9	zymosan	zymosan	NNP
cord-287670-z6ckhkgg	118	10	particles	particle	NNS
cord-287670-z6ckhkgg	118	11	as	as	RB
cord-287670-z6ckhkgg	118	12	well	well	RB
cord-287670-z6ckhkgg	118	13	as	as	IN
cord-287670-z6ckhkgg	118	14	to	to	IN
cord-287670-z6ckhkgg	118	15	the	the	DT
cord-287670-z6ckhkgg	118	16	yeast	yeast	NN
cord-287670-z6ckhkgg	118	17	form	form	NN
cord-287670-z6ckhkgg	118	18	of	of	IN
cord-287670-z6ckhkgg	118	19	P.	P.	NNP
cord-287670-z6ckhkgg	118	20	brasiliensis	brasiliensis	NN
cord-287670-z6ckhkgg	118	21	,	,	,
cord-287670-z6ckhkgg	118	22	was	be	VBD
cord-287670-z6ckhkgg	118	23	found	find	VBN
cord-287670-z6ckhkgg	118	24	to	to	TO
cord-287670-z6ckhkgg	118	25	induce	induce	VB
cord-287670-z6ckhkgg	118	26	their	-PRON-	PRP$
cord-287670-z6ckhkgg	118	27	aggregation	aggregation	NN
cord-287670-z6ckhkgg	118	28	and	and	CC
cord-287670-z6ckhkgg	118	29	phagocytosis	phagocytosis	NN
cord-287670-z6ckhkgg	118	30	by	by	IN
cord-287670-z6ckhkgg	118	31	macrophages	macrophage	NNS
cord-287670-z6ckhkgg	118	32	(	(	-LRB-
cord-287670-z6ckhkgg	118	33	in	in	IN
cord-287670-z6ckhkgg	118	34	high	high	JJ
cord-287670-z6ckhkgg	118	35	numbers	number	NNS
cord-287670-z6ckhkgg	118	36	)	)	-RRB-
cord-287670-z6ckhkgg	118	37	through	through	IN
cord-287670-z6ckhkgg	118	38	a	a	DT
cord-287670-z6ckhkgg	118	39	Dectin-1-dependent	dectin-1-dependent	JJ
cord-287670-z6ckhkgg	118	40	mechanism	mechanism	NN
cord-287670-z6ckhkgg	118	41	,	,	,
cord-287670-z6ckhkgg	118	42	as	as	IN
cord-287670-z6ckhkgg	118	43	demonstrated	demonstrate	VBN
cord-287670-z6ckhkgg	118	44	using	use	VBG
cord-287670-z6ckhkgg	118	45	blocking	block	VBG
cord-287670-z6ckhkgg	118	46	anti	anti	JJ
cord-287670-z6ckhkgg	118	47	-	-	JJ
cord-287670-z6ckhkgg	118	48	Dectin-1	Dectin-1	NNP
cord-287670-z6ckhkgg	118	49	antibodies	antibody	NNS
cord-287670-z6ckhkgg	118	50	[	[	-LRB-
cord-287670-z6ckhkgg	118	51	38	38	CD
cord-287670-z6ckhkgg	118	52	]	]	-RRB-
cord-287670-z6ckhkgg	118	53	.	.	.
cord-287670-z6ckhkgg	119	1	Moreover	moreover	RB
cord-287670-z6ckhkgg	119	2	,	,	,
cord-287670-z6ckhkgg	119	3	SNPs	SNPs	NNPS
cord-287670-z6ckhkgg	119	4	and	and	CC
cord-287670-z6ckhkgg	119	5	haplotypes	haplotype	NNS
cord-287670-z6ckhkgg	119	6	in	in	IN
cord-287670-z6ckhkgg	119	7	the	the	DT
cord-287670-z6ckhkgg	119	8	human	human	JJ
cord-287670-z6ckhkgg	119	9	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	119	10	gene	gene	NN
cord-287670-z6ckhkgg	119	11	have	have	VBP
cord-287670-z6ckhkgg	119	12	been	be	VBN
cord-287670-z6ckhkgg	119	13	associated	associate	VBN
cord-287670-z6ckhkgg	119	14	with	with	IN
cord-287670-z6ckhkgg	119	15	high	high	JJ
cord-287670-z6ckhkgg	119	16	susceptibility	susceptibility	NN
cord-287670-z6ckhkgg	119	17	to	to	IN
cord-287670-z6ckhkgg	119	18	invasive	invasive	JJ
cord-287670-z6ckhkgg	119	19	aspergillosis	aspergillosis	NN
cord-287670-z6ckhkgg	119	20	following	follow	VBG
cord-287670-z6ckhkgg	119	21	allogeneic	allogeneic	NN
cord-287670-z6ckhkgg	119	22	hematopoietic	hematopoietic	JJ
cord-287670-z6ckhkgg	119	23	stem	stem	NN
cord-287670-z6ckhkgg	119	24	-	-	HYPH
cord-287670-z6ckhkgg	119	25	cell	cell	NN
cord-287670-z6ckhkgg	119	26	transplantation	transplantation	NN
cord-287670-z6ckhkgg	119	27	[	[	-LRB-
cord-287670-z6ckhkgg	119	28	43	43	CD
cord-287670-z6ckhkgg	119	29	]	]	-RRB-
cord-287670-z6ckhkgg	119	30	.	.	.
cord-287670-z6ckhkgg	120	1	Since	since	IN
cord-287670-z6ckhkgg	120	2	then	then	RB
cord-287670-z6ckhkgg	120	3	,	,	,
cord-287670-z6ckhkgg	120	4	a	a	DT
cord-287670-z6ckhkgg	120	5	link	link	NN
cord-287670-z6ckhkgg	120	6	between	between	IN
cord-287670-z6ckhkgg	120	7	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	120	8	genetic	genetic	JJ
cord-287670-z6ckhkgg	120	9	variants	variant	NNS
cord-287670-z6ckhkgg	120	10	and	and	CC
cord-287670-z6ckhkgg	120	11	susceptibility	susceptibility	NN
cord-287670-z6ckhkgg	120	12	to	to	IN
cord-287670-z6ckhkgg	120	13	mold	mold	NN
cord-287670-z6ckhkgg	120	14	infections	infection	NNS
cord-287670-z6ckhkgg	120	15	has	have	VBZ
cord-287670-z6ckhkgg	120	16	been	be	VBN
cord-287670-z6ckhkgg	120	17	confirmed	confirm	VBN
cord-287670-z6ckhkgg	120	18	for	for	IN
cord-287670-z6ckhkgg	120	19	more	more	JJR
cord-287670-z6ckhkgg	120	20	than	than	IN
cord-287670-z6ckhkgg	120	21	1000	1000	CD
cord-287670-z6ckhkgg	120	22	patients	patient	NNS
cord-287670-z6ckhkgg	120	23	in	in	IN
cord-287670-z6ckhkgg	120	24	the	the	DT
cord-287670-z6ckhkgg	120	25	Swiss	Swiss	NNP
cord-287670-z6ckhkgg	120	26	Organ	Organ	NNP
cord-287670-z6ckhkgg	120	27	Transplantation	Transplantation	NNP
cord-287670-z6ckhkgg	120	28	Cohort	Cohort	NNP
cord-287670-z6ckhkgg	120	29	[	[	-LRB-
cord-287670-z6ckhkgg	120	30	44	44	CD
cord-287670-z6ckhkgg	120	31	]	]	-RRB-
cord-287670-z6ckhkgg	120	32	as	as	RB
cord-287670-z6ckhkgg	120	33	well	well	RB
cord-287670-z6ckhkgg	120	34	as	as	IN
cord-287670-z6ckhkgg	120	35	in	in	IN
cord-287670-z6ckhkgg	120	36	a	a	DT
cord-287670-z6ckhkgg	120	37	small	small	JJ
cord-287670-z6ckhkgg	120	38	cohort	cohort	NN
cord-287670-z6ckhkgg	120	39	of	of	IN
cord-287670-z6ckhkgg	120	40	lung	lung	NN
cord-287670-z6ckhkgg	120	41	transplantation	transplantation	NN
cord-287670-z6ckhkgg	120	42	patients	patient	NNS
cord-287670-z6ckhkgg	120	43	[	[	-LRB-
cord-287670-z6ckhkgg	120	44	45	45	CD
cord-287670-z6ckhkgg	120	45	]	]	-RRB-
cord-287670-z6ckhkgg	120	46	.	.	.
cord-287670-z6ckhkgg	121	1	This	this	DT
cord-287670-z6ckhkgg	121	2	indicates	indicate	VBZ
cord-287670-z6ckhkgg	121	3	that	that	IN
cord-287670-z6ckhkgg	121	4	the	the	DT
cord-287670-z6ckhkgg	121	5	results	result	NNS
cord-287670-z6ckhkgg	121	6	obtained	obtain	VBN
cord-287670-z6ckhkgg	121	7	with	with	IN
cord-287670-z6ckhkgg	121	8	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	121	9	in	in	IN
cord-287670-z6ckhkgg	121	10	mouse	mouse	NN
cord-287670-z6ckhkgg	121	11	models	model	NNS
cord-287670-z6ckhkgg	121	12	of	of	IN
cord-287670-z6ckhkgg	121	13	fungal	fungal	JJ
cord-287670-z6ckhkgg	121	14	infections	infection	NNS
cord-287670-z6ckhkgg	121	15	can	can	MD
cord-287670-z6ckhkgg	121	16	be	be	VB
cord-287670-z6ckhkgg	121	17	translated	translate	VBN
cord-287670-z6ckhkgg	121	18	to	to	IN
cord-287670-z6ckhkgg	121	19	human	human	JJ
cord-287670-z6ckhkgg	121	20	scenarios	scenario	NNS
cord-287670-z6ckhkgg	121	21	.	.	.
cord-287670-z6ckhkgg	122	1	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	122	2	can	can	MD
cord-287670-z6ckhkgg	122	3	also	also	RB
cord-287670-z6ckhkgg	122	4	bind	bind	VB
cord-287670-z6ckhkgg	122	5	various	various	JJ
cord-287670-z6ckhkgg	122	6	bacteria	bacteria	NNS
cord-287670-z6ckhkgg	122	7	,	,	,
cord-287670-z6ckhkgg	122	8	including	include	VBG
cord-287670-z6ckhkgg	122	9	Pseudomonas	Pseudomonas	NNP
cord-287670-z6ckhkgg	122	10	aeruginosa	aeruginosa	NN
cord-287670-z6ckhkgg	122	11	,	,	,
cord-287670-z6ckhkgg	122	12	Klebsiella	Klebsiella	NNP
cord-287670-z6ckhkgg	122	13	pneumoniae	pneumoniae	NN
cord-287670-z6ckhkgg	122	14	,	,	,
cord-287670-z6ckhkgg	122	15	Neisseria	Neisseria	NNP
cord-287670-z6ckhkgg	122	16	meningitidis	meningitidis	NN
cord-287670-z6ckhkgg	122	17	,	,	,
cord-287670-z6ckhkgg	122	18	and	and	CC
cord-287670-z6ckhkgg	122	19	UPEC	UPEC	NNP
cord-287670-z6ckhkgg	122	20	[	[	-LRB-
cord-287670-z6ckhkgg	122	21	13	13	CD
cord-287670-z6ckhkgg	122	22	,	,	,
cord-287670-z6ckhkgg	122	23	14	14	CD
cord-287670-z6ckhkgg	122	24	,	,	,
cord-287670-z6ckhkgg	122	25	37	37	CD
cord-287670-z6ckhkgg	122	26	,	,	,
cord-287670-z6ckhkgg	122	27	39	39	CD
cord-287670-z6ckhkgg	122	28	,	,	,
cord-287670-z6ckhkgg	122	29	46	46	CD
cord-287670-z6ckhkgg	122	30	]	]	-RRB-
cord-287670-z6ckhkgg	122	31	.	.	.
cord-287670-z6ckhkgg	123	1	In	in	IN
cord-287670-z6ckhkgg	123	2	particular	particular	JJ
cord-287670-z6ckhkgg	123	3	,	,	,
cord-287670-z6ckhkgg	123	4	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	123	5	has	have	VBZ
cord-287670-z6ckhkgg	123	6	been	be	VBN
cord-287670-z6ckhkgg	123	7	reported	report	VBN
cord-287670-z6ckhkgg	123	8	to	to	TO
cord-287670-z6ckhkgg	123	9	behave	behave	VB
cord-287670-z6ckhkgg	123	10	as	as	IN
cord-287670-z6ckhkgg	123	11	an	an	DT
cord-287670-z6ckhkgg	123	12	opsonin	opsonin	NNS
cord-287670-z6ckhkgg	123	13	of	of	IN
cord-287670-z6ckhkgg	123	14	P.	P.	NNP
cord-287670-z6ckhkgg	123	15	aeruginosa	aeruginosa	NN
cord-287670-z6ckhkgg	123	16	and	and	CC
cord-287670-z6ckhkgg	123	17	UPEC	UPEC	NNP
cord-287670-z6ckhkgg	123	18	,	,	,
cord-287670-z6ckhkgg	123	19	facilitating	facilitate	VBG
cord-287670-z6ckhkgg	123	20	their	-PRON-	PRP$
cord-287670-z6ckhkgg	123	21	recognition	recognition	NN
cord-287670-z6ckhkgg	123	22	and	and	CC
cord-287670-z6ckhkgg	123	23	ingestion	ingestion	NN
cord-287670-z6ckhkgg	123	24	by	by	IN
cord-287670-z6ckhkgg	123	25	human	human	NN
cord-287670-z6ckhkgg	123	26	and	and	CC
cord-287670-z6ckhkgg	123	27	mouse	mouse	NN
cord-287670-z6ckhkgg	123	28	phagocytes	phagocyte	NNS
cord-287670-z6ckhkgg	123	29	[	[	-LRB-
cord-287670-z6ckhkgg	123	30	14	14	CD
cord-287670-z6ckhkgg	123	31	,	,	,
cord-287670-z6ckhkgg	123	32	39	39	CD
cord-287670-z6ckhkgg	123	33	]	]	-RRB-
cord-287670-z6ckhkgg	124	1	(	(	-LRB-
cord-287670-z6ckhkgg	124	2	Figure	figure	NN
cord-287670-z6ckhkgg	124	3	2	2	CD
cord-287670-z6ckhkgg	124	4	)	)	-RRB-
cord-287670-z6ckhkgg	124	5	.	.	.
cord-287670-z6ckhkgg	125	1	Accordingly	accordingly	RB
cord-287670-z6ckhkgg	125	2	,	,	,
cord-287670-z6ckhkgg	125	3	in	in	IN
cord-287670-z6ckhkgg	125	4	acute	acute	JJ
cord-287670-z6ckhkgg	125	5	and	and	CC
cord-287670-z6ckhkgg	125	6	chronic	chronic	JJ
cord-287670-z6ckhkgg	125	7	models	model	NNS
cord-287670-z6ckhkgg	125	8	of	of	IN
cord-287670-z6ckhkgg	125	9	P.	P.	NNP
cord-287670-z6ckhkgg	125	10	aeruginosa	aeruginosa	NN
cord-287670-z6ckhkgg	125	11	lung	lung	NN
cord-287670-z6ckhkgg	125	12	infection	infection	NN
cord-287670-z6ckhkgg	125	13	in	in	IN
cord-287670-z6ckhkgg	125	14	mice	mouse	NNS
cord-287670-z6ckhkgg	126	1	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	126	2	has	have	VBZ
cord-287670-z6ckhkgg	126	3	exhibited	exhibit	VBN
cord-287670-z6ckhkgg	126	4	therapeutic	therapeutic	JJ
cord-287670-z6ckhkgg	126	5	outcomes	outcome	NNS
cord-287670-z6ckhkgg	126	6	such	such	JJ
cord-287670-z6ckhkgg	126	7	as	as	IN
cord-287670-z6ckhkgg	126	8	reduced	reduce	VBN
cord-287670-z6ckhkgg	126	9	bacterial	bacterial	JJ
cord-287670-z6ckhkgg	126	10	burden	burden	NN
cord-287670-z6ckhkgg	126	11	and	and	CC
cord-287670-z6ckhkgg	126	12	inflammation	inflammation	NN
cord-287670-z6ckhkgg	126	13	[	[	-LRB-
cord-287670-z6ckhkgg	126	14	47	47	CD
cord-287670-z6ckhkgg	126	15	,	,	,
cord-287670-z6ckhkgg	126	16	48	48	CD
cord-287670-z6ckhkgg	126	17	]	]	-RRB-
cord-287670-z6ckhkgg	126	18	.	.	.
cord-287670-z6ckhkgg	127	1	In	in	IN
cord-287670-z6ckhkgg	127	2	addition	addition	NN
cord-287670-z6ckhkgg	127	3	,	,	,
cord-287670-z6ckhkgg	127	4	in	in	IN
cord-287670-z6ckhkgg	127	5	UTIs	uti	NNS
cord-287670-z6ckhkgg	127	6	,	,	,
cord-287670-z6ckhkgg	127	7	uroepithelial	uroepithelial	JJ
cord-287670-z6ckhkgg	127	8	cells	cell	NNS
cord-287670-z6ckhkgg	127	9	have	have	VBP
cord-287670-z6ckhkgg	127	10	been	be	VBN
cord-287670-z6ckhkgg	127	11	found	find	VBN
cord-287670-z6ckhkgg	127	12	to	to	TO
cord-287670-z6ckhkgg	127	13	rapidly	rapidly	RB
cord-287670-z6ckhkgg	127	14	express	express	VB
cord-287670-z6ckhkgg	127	15	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	127	16	in	in	IN
cord-287670-z6ckhkgg	127	17	response	response	NN
cord-287670-z6ckhkgg	127	18	to	to	IN
cord-287670-z6ckhkgg	127	19	UPEC	upec	JJ
cord-287670-z6ckhkgg	127	20	infection	infection	NN
cord-287670-z6ckhkgg	127	21	in	in	IN
cord-287670-z6ckhkgg	127	22	mice	mouse	NNS
cord-287670-z6ckhkgg	127	23	and	and	CC
cord-287670-z6ckhkgg	127	24	humans	human	NNS
cord-287670-z6ckhkgg	127	25	,	,	,
cord-287670-z6ckhkgg	127	26	with	with	IN
cord-287670-z6ckhkgg	127	27	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	127	28	augmenting	augment	VBG
cord-287670-z6ckhkgg	127	29	phagocytosis	phagocytosis	NN
cord-287670-z6ckhkgg	127	30	by	by	RB
cord-287670-z6ckhkgg	127	31	,	,	,
cord-287670-z6ckhkgg	127	32	and	and	CC
cord-287670-z6ckhkgg	127	33	phagosome	phagosome	NN
cord-287670-z6ckhkgg	127	34	maturation	maturation	NN
cord-287670-z6ckhkgg	127	35	in	in	IN
cord-287670-z6ckhkgg	127	36	,	,	,
cord-287670-z6ckhkgg	127	37	peripheral	peripheral	JJ
cord-287670-z6ckhkgg	127	38	blood	blood	NN
cord-287670-z6ckhkgg	127	39	neutrophils	neutrophil	NNS
cord-287670-z6ckhkgg	127	40	[	[	-LRB-
cord-287670-z6ckhkgg	127	41	14	14	CD
cord-287670-z6ckhkgg	127	42	]	]	-RRB-
cord-287670-z6ckhkgg	127	43	.	.	.
cord-287670-z6ckhkgg	128	1	In	in	IN
cord-287670-z6ckhkgg	128	2	agreement	agreement	NN
cord-287670-z6ckhkgg	128	3	with	with	IN
cord-287670-z6ckhkgg	128	4	these	these	DT
cord-287670-z6ckhkgg	128	5	findings	finding	NNS
cord-287670-z6ckhkgg	128	6	,	,	,
cord-287670-z6ckhkgg	128	7	global	global	JJ
cord-287670-z6ckhkgg	128	8	PTX3-deficient	PTX3-deficient	NNP
cord-287670-z6ckhkgg	128	9	mice	mouse	NNS
cord-287670-z6ckhkgg	128	10	displayed	display	VBD
cord-287670-z6ckhkgg	128	11	a	a	DT
cord-287670-z6ckhkgg	128	12	defective	defective	JJ
cord-287670-z6ckhkgg	128	13	capacity	capacity	NN
cord-287670-z6ckhkgg	128	14	to	to	TO
cord-287670-z6ckhkgg	128	15	clear	clear	JJ
cord-287670-z6ckhkgg	128	16	bacteria	bacteria	NNS
cord-287670-z6ckhkgg	128	17	concomitant	concomitant	JJ
cord-287670-z6ckhkgg	128	18	with	with	IN
cord-287670-z6ckhkgg	128	19	an	an	DT
cord-287670-z6ckhkgg	128	20	exacerbated	exacerbate	VBN
cord-287670-z6ckhkgg	128	21	inflammatory	inflammatory	JJ
cord-287670-z6ckhkgg	128	22	response	response	NN
cord-287670-z6ckhkgg	128	23	,	,	,
cord-287670-z6ckhkgg	128	24	as	as	IN
cord-287670-z6ckhkgg	128	25	evidenced	evidence	VBN
cord-287670-z6ckhkgg	128	26	by	by	IN
cord-287670-z6ckhkgg	128	27	increased	increase	VBN
cord-287670-z6ckhkgg	128	28	production	production	NN
cord-287670-z6ckhkgg	128	29	of	of	IN
cord-287670-z6ckhkgg	128	30	inflammatory	inflammatory	JJ
cord-287670-z6ckhkgg	128	31	mediators	mediator	NNS
cord-287670-z6ckhkgg	128	32	and	and	CC
cord-287670-z6ckhkgg	128	33	leukocyte	leukocyte	NN
cord-287670-z6ckhkgg	128	34	recruitment	recruitment	NN
cord-287670-z6ckhkgg	128	35	in	in	IN
cord-287670-z6ckhkgg	128	36	the	the	DT
cord-287670-z6ckhkgg	128	37	urinary	urinary	JJ
cord-287670-z6ckhkgg	128	38	tract	tract	NN
cord-287670-z6ckhkgg	128	39	[	[	-LRB-
cord-287670-z6ckhkgg	128	40	14	14	CD
cord-287670-z6ckhkgg	128	41	]	]	-RRB-
cord-287670-z6ckhkgg	128	42	.	.	.
cord-287670-z6ckhkgg	129	1	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	129	2	binds	bind	VBZ
cord-287670-z6ckhkgg	129	3	to	to	IN
cord-287670-z6ckhkgg	129	4	outer	outer	JJ
cord-287670-z6ckhkgg	129	5	membrane	membrane	NN
cord-287670-z6ckhkgg	129	6	vesicles	vesicle	NNS
cord-287670-z6ckhkgg	129	7	(	(	-LRB-
cord-287670-z6ckhkgg	129	8	OMVs	omv	NNS
cord-287670-z6ckhkgg	129	9	)	)	-RRB-
cord-287670-z6ckhkgg	129	10	from	from	IN
cord-287670-z6ckhkgg	129	11	N.	N.	NNP
cord-287670-z6ckhkgg	129	12	meningitidis	meningitidis	NNP
cord-287670-z6ckhkgg	129	13	and	and	CC
cord-287670-z6ckhkgg	129	14	to	to	IN
cord-287670-z6ckhkgg	129	15	three	three	CD
cord-287670-z6ckhkgg	129	16	selected	select	VBN
cord-287670-z6ckhkgg	129	17	meningococcal	meningococcal	JJ
cord-287670-z6ckhkgg	129	18	molecules	molecule	NNS
cord-287670-z6ckhkgg	129	19	(	(	-LRB-
cord-287670-z6ckhkgg	129	20	GNA0667	GNA0667	NNS
cord-287670-z6ckhkgg	129	21	,	,	,
cord-287670-z6ckhkgg	129	22	GNA1030	GNA1030	NNP
cord-287670-z6ckhkgg	129	23	,	,	,
cord-287670-z6ckhkgg	129	24	and	and	CC
cord-287670-z6ckhkgg	129	25	GNA2091	GNA2091	NNP
cord-287670-z6ckhkgg	129	26	)	)	-RRB-
cord-287670-z6ckhkgg	129	27	[	[	-LRB-
cord-287670-z6ckhkgg	129	28	13	13	CD
cord-287670-z6ckhkgg	129	29	]	]	-RRB-
cord-287670-z6ckhkgg	129	30	.	.	.
cord-287670-z6ckhkgg	130	1	Moreover	moreover	RB
cord-287670-z6ckhkgg	130	2	,	,	,
cord-287670-z6ckhkgg	130	3	global	global	JJ
cord-287670-z6ckhkgg	130	4	PTX3deficient	PTX3deficient	NNP
cord-287670-z6ckhkgg	130	5	mice	mouse	NNS
cord-287670-z6ckhkgg	130	6	have	have	VBP
cord-287670-z6ckhkgg	130	7	shown	show	VBN
cord-287670-z6ckhkgg	130	8	a	a	DT
cord-287670-z6ckhkgg	130	9	defective	defective	JJ
cord-287670-z6ckhkgg	130	10	antibody	antibody	NN
cord-287670-z6ckhkgg	130	11	response	response	NN
cord-287670-z6ckhkgg	130	12	in	in	IN
cord-287670-z6ckhkgg	130	13	vaccination	vaccination	NN
cord-287670-z6ckhkgg	130	14	protocols	protocol	NNS
cord-287670-z6ckhkgg	130	15	using	use	VBG
cord-287670-z6ckhkgg	130	16	N.	N.	NNP
cord-287670-z6ckhkgg	130	17	meningitidis	meningitidis	NNP
cord-287670-z6ckhkgg	130	18	OMV	OMV	NNP
cord-287670-z6ckhkgg	130	19	,	,	,
cord-287670-z6ckhkgg	130	20	while	while	IN
cord-287670-z6ckhkgg	130	21	coadministration	coadministration	NN
cord-287670-z6ckhkgg	130	22	of	of	IN
cord-287670-z6ckhkgg	130	23	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	130	24	was	be	VBD
cord-287670-z6ckhkgg	130	25	found	find	VBN
cord-287670-z6ckhkgg	130	26	to	to	TO
cord-287670-z6ckhkgg	130	27	increase	increase	VB
cord-287670-z6ckhkgg	130	28	antibody	antibody	NN
cord-287670-z6ckhkgg	130	29	responses	response	NNS
cord-287670-z6ckhkgg	130	30	relative	relative	JJ
cord-287670-z6ckhkgg	130	31	to	to	IN
cord-287670-z6ckhkgg	130	32	controls	control	NNS
cord-287670-z6ckhkgg	130	33	.	.	.
cord-287670-z6ckhkgg	131	1	Importantly	importantly	RB
cord-287670-z6ckhkgg	131	2	,	,	,
cord-287670-z6ckhkgg	131	3	administration	administration	NN
cord-287670-z6ckhkgg	131	4	of	of	IN
cord-287670-z6ckhkgg	131	5	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	131	6	reversed	reverse	VBD
cord-287670-z6ckhkgg	131	7	the	the	DT
cord-287670-z6ckhkgg	131	8	defective	defective	JJ
cord-287670-z6ckhkgg	131	9	humoral	humoral	JJ
cord-287670-z6ckhkgg	131	10	responses	response	NNS
cord-287670-z6ckhkgg	131	11	to	to	IN
cord-287670-z6ckhkgg	131	12	vaccination	vaccination	NN
cord-287670-z6ckhkgg	131	13	with	with	IN
cord-287670-z6ckhkgg	131	14	OMV	OMV	NNP
cord-287670-z6ckhkgg	131	15	of	of	IN
cord-287670-z6ckhkgg	131	16	PTX3-deficient	PTX3-deficient	NNP
cord-287670-z6ckhkgg	131	17	mice	mouse	NNS
cord-287670-z6ckhkgg	131	18	but	but	CC
cord-287670-z6ckhkgg	131	19	also	also	RB
cord-287670-z6ckhkgg	131	20	protected	protect	VBD
cord-287670-z6ckhkgg	131	21	infant	infant	JJ
cord-287670-z6ckhkgg	131	22	rats	rat	NNS
cord-287670-z6ckhkgg	131	23	from	from	IN
cord-287670-z6ckhkgg	131	24	infection	infection	NN
cord-287670-z6ckhkgg	131	25	when	when	WRB
cord-287670-z6ckhkgg	131	26	they	-PRON-	PRP
cord-287670-z6ckhkgg	131	27	were	be	VBD
cord-287670-z6ckhkgg	131	28	challenged	challenge	VBN
cord-287670-z6ckhkgg	131	29	with	with	IN
cord-287670-z6ckhkgg	131	30	N.	N.	NNP
cord-287670-z6ckhkgg	131	31	meningitidis	meningitidis	NNP
cord-287670-z6ckhkgg	131	32	[	[	-LRB-
cord-287670-z6ckhkgg	131	33	13	13	CD
cord-287670-z6ckhkgg	131	34	]	]	-RRB-
cord-287670-z6ckhkgg	131	35	.	.	.
cord-287670-z6ckhkgg	132	1	These	these	DT
cord-287670-z6ckhkgg	132	2	results	result	NNS
cord-287670-z6ckhkgg	132	3	indicate	indicate	VBP
cord-287670-z6ckhkgg	132	4	that	that	IN
cord-287670-z6ckhkgg	132	5	even	even	RB
cord-287670-z6ckhkgg	132	6	if	if	IN
cord-287670-z6ckhkgg	132	7	a	a	DT
cord-287670-z6ckhkgg	132	8	direct	direct	JJ
cord-287670-z6ckhkgg	132	9	effect	effect	NN
cord-287670-z6ckhkgg	132	10	of	of	IN
cord-287670-z6ckhkgg	132	11	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	132	12	in	in	IN
cord-287670-z6ckhkgg	132	13	adaptive	adaptive	JJ
cord-287670-z6ckhkgg	132	14	immune	immune	JJ
cord-287670-z6ckhkgg	132	15	responses	response	NNS
cord-287670-z6ckhkgg	132	16	has	have	VBZ
cord-287670-z6ckhkgg	132	17	not	not	RB
cord-287670-z6ckhkgg	132	18	been	be	VBN
cord-287670-z6ckhkgg	132	19	described	describe	VBN
cord-287670-z6ckhkgg	132	20	so	so	RB
cord-287670-z6ckhkgg	132	21	far	far	RB
cord-287670-z6ckhkgg	132	22	,	,	,
cord-287670-z6ckhkgg	132	23	the	the	DT
cord-287670-z6ckhkgg	132	24	PTX3dependent	PTX3dependent	NNP
cord-287670-z6ckhkgg	132	25	facilitated	facilitate	VBD
cord-287670-z6ckhkgg	132	26	recognition	recognition	NN
cord-287670-z6ckhkgg	132	27	of	of	IN
cord-287670-z6ckhkgg	132	28	microbial	microbial	JJ
cord-287670-z6ckhkgg	132	29	components	component	NNS
cord-287670-z6ckhkgg	132	30	by	by	IN
cord-287670-z6ckhkgg	132	31	antigen	antigen	NN
cord-287670-z6ckhkgg	132	32	-	-	HYPH
cord-287670-z6ckhkgg	132	33	presenting	present	VBG
cord-287670-z6ckhkgg	132	34	cells	cell	NNS
cord-287670-z6ckhkgg	132	35	results	result	NNS
cord-287670-z6ckhkgg	132	36	in	in	IN
cord-287670-z6ckhkgg	132	37	improved	improve	VBN
cord-287670-z6ckhkgg	132	38	adaptive	adaptive	JJ
cord-287670-z6ckhkgg	132	39	immune	immune	JJ
cord-287670-z6ckhkgg	132	40	responses	response	NNS
cord-287670-z6ckhkgg	132	41	.	.	.
cord-287670-z6ckhkgg	133	1	The	the	DT
cord-287670-z6ckhkgg	133	2	relevance	relevance	NN
cord-287670-z6ckhkgg	133	3	in	in	IN
cord-287670-z6ckhkgg	133	4	humans	human	NNS
cord-287670-z6ckhkgg	133	5	of	of	IN
cord-287670-z6ckhkgg	133	6	the	the	DT
cord-287670-z6ckhkgg	133	7	results	result	NNS
cord-287670-z6ckhkgg	133	8	obtained	obtain	VBN
cord-287670-z6ckhkgg	133	9	in	in	IN
cord-287670-z6ckhkgg	133	10	bacterial	bacterial	JJ
cord-287670-z6ckhkgg	133	11	infection	infection	NN
cord-287670-z6ckhkgg	133	12	animal	animal	NN
cord-287670-z6ckhkgg	133	13	models	model	NNS
cord-287670-z6ckhkgg	133	14	has	have	VBZ
cord-287670-z6ckhkgg	133	15	been	be	VBN
cord-287670-z6ckhkgg	133	16	confirmed	confirm	VBN
cord-287670-z6ckhkgg	133	17	by	by	IN
cord-287670-z6ckhkgg	133	18	several	several	JJ
cord-287670-z6ckhkgg	133	19	genetic	genetic	JJ
cord-287670-z6ckhkgg	133	20	studies	study	NNS
cord-287670-z6ckhkgg	133	21	showing	show	VBG
cord-287670-z6ckhkgg	133	22	a	a	DT
cord-287670-z6ckhkgg	133	23	clear	clear	JJ
cord-287670-z6ckhkgg	133	24	association	association	NN
cord-287670-z6ckhkgg	133	25	between	between	IN
cord-287670-z6ckhkgg	133	26	specific	specific	JJ
cord-287670-z6ckhkgg	133	27	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	133	28	genetic	genetic	JJ
cord-287670-z6ckhkgg	133	29	variants	variant	NNS
cord-287670-z6ckhkgg	133	30	and	and	CC
cord-287670-z6ckhkgg	133	31	augmented	augment	VBN
cord-287670-z6ckhkgg	133	32	susceptibility	susceptibility	NN
cord-287670-z6ckhkgg	133	33	to	to	IN
cord-287670-z6ckhkgg	133	34	Mycobacterium	Mycobacterium	NNP
cord-287670-z6ckhkgg	133	35	tuberculosis	tuberculosis	NN
cord-287670-z6ckhkgg	133	36	pulmonary	pulmonary	JJ
cord-287670-z6ckhkgg	133	37	infection	infection	NN
cord-287670-z6ckhkgg	133	38	[	[	-LRB-
cord-287670-z6ckhkgg	133	39	49	49	CD
cord-287670-z6ckhkgg	133	40	]	]	-RRB-
cord-287670-z6ckhkgg	133	41	,	,	,
cord-287670-z6ckhkgg	133	42	acute	acute	JJ
cord-287670-z6ckhkgg	133	43	pyelonephritis	pyelonephritis	NN
cord-287670-z6ckhkgg	133	44	and	and	CC
cord-287670-z6ckhkgg	133	45	cystitis	cystitis	NN
cord-287670-z6ckhkgg	133	46	[	[	-LRB-
cord-287670-z6ckhkgg	133	47	14	14	CD
cord-287670-z6ckhkgg	133	48	]	]	-RRB-
cord-287670-z6ckhkgg	133	49	,	,	,
cord-287670-z6ckhkgg	133	50	or	or	CC
cord-287670-z6ckhkgg	133	51	P.	P.	NNP
cord-287670-z6ckhkgg	133	52	aeruginosa	aeruginosa	NN
cord-287670-z6ckhkgg	133	53	lung	lung	NN
cord-287670-z6ckhkgg	133	54	infection	infection	NN
cord-287670-z6ckhkgg	133	55	in	in	IN
cord-287670-z6ckhkgg	133	56	cystic	cystic	JJ
cord-287670-z6ckhkgg	133	57	fibrosis	fibrosis	NN
cord-287670-z6ckhkgg	133	58	patients	patient	NNS
cord-287670-z6ckhkgg	133	59	[	[	-LRB-
cord-287670-z6ckhkgg	133	60	50	50	CD
cord-287670-z6ckhkgg	133	61	]	]	-RRB-
cord-287670-z6ckhkgg	133	62	.	.	.
cord-287670-z6ckhkgg	134	1	Regarding	regard	VBG
cord-287670-z6ckhkgg	134	2	viral	viral	JJ
cord-287670-z6ckhkgg	134	3	infections	infection	NNS
cord-287670-z6ckhkgg	134	4	,	,	,
cord-287670-z6ckhkgg	134	5	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	134	6	has	have	VBZ
cord-287670-z6ckhkgg	134	7	been	be	VBN
cord-287670-z6ckhkgg	134	8	proposed	propose	VBN
cord-287670-z6ckhkgg	134	9	to	to	TO
cord-287670-z6ckhkgg	134	10	play	play	VB
cord-287670-z6ckhkgg	134	11	a	a	DT
cord-287670-z6ckhkgg	134	12	protective	protective	JJ
cord-287670-z6ckhkgg	134	13	role	role	NN
cord-287670-z6ckhkgg	134	14	in	in	IN
cord-287670-z6ckhkgg	134	15	defense	defense	NN
cord-287670-z6ckhkgg	134	16	against	against	IN
cord-287670-z6ckhkgg	134	17	viruses	virus	NNS
cord-287670-z6ckhkgg	134	18	such	such	JJ
cord-287670-z6ckhkgg	134	19	as	as	IN
cord-287670-z6ckhkgg	134	20	human	human	JJ
cord-287670-z6ckhkgg	134	21	and	and	CC
cord-287670-z6ckhkgg	134	22	murine	murine	JJ
cord-287670-z6ckhkgg	134	23	cytomegalovirus	cytomegalovirus	NN
cord-287670-z6ckhkgg	134	24	(	(	-LRB-
cord-287670-z6ckhkgg	134	25	CMV	CMV	NNP
cord-287670-z6ckhkgg	134	26	)	)	-RRB-
cord-287670-z6ckhkgg	134	27	and	and	CC
cord-287670-z6ckhkgg	134	28	influenza	influenza	NN
cord-287670-z6ckhkgg	134	29	virus	virus	NN
cord-287670-z6ckhkgg	134	30	type	type	NN
cord-287670-z6ckhkgg	134	31	A	a	NN
cord-287670-z6ckhkgg	134	32	(	(	-LRB-
cord-287670-z6ckhkgg	134	33	IVA	IVA	NNP
cord-287670-z6ckhkgg	134	34	)	)	-RRB-
cord-287670-z6ckhkgg	134	35	[	[	-LRB-
cord-287670-z6ckhkgg	134	36	29	29	CD
cord-287670-z6ckhkgg	134	37	,	,	,
cord-287670-z6ckhkgg	134	38	51	51	CD
cord-287670-z6ckhkgg	134	39	]	]	-RRB-
cord-287670-z6ckhkgg	135	1	(	(	-LRB-
cord-287670-z6ckhkgg	135	2	Figure	figure	NN
cord-287670-z6ckhkgg	135	3	2	2	CD
cord-287670-z6ckhkgg	135	4	)	)	-RRB-
cord-287670-z6ckhkgg	135	5	.	.	.
cord-287670-z6ckhkgg	136	1	Increased	increase	VBN
cord-287670-z6ckhkgg	136	2	susceptibility	susceptibility	NN
cord-287670-z6ckhkgg	136	3	to	to	IN
cord-287670-z6ckhkgg	136	4	CMV	CMV	NNP
cord-287670-z6ckhkgg	136	5	infection	infection	NN
cord-287670-z6ckhkgg	136	6	and	and	CC
cord-287670-z6ckhkgg	136	7	to	to	IN
cord-287670-z6ckhkgg	136	8	specific	specific	JJ
cord-287670-z6ckhkgg	136	9	strains	strain	NNS
cord-287670-z6ckhkgg	136	10	of	of	IN
cord-287670-z6ckhkgg	136	11	influenza	influenza	NN
cord-287670-z6ckhkgg	136	12	virus	virus	NN
cord-287670-z6ckhkgg	136	13	infections	infection	NNS
cord-287670-z6ckhkgg	136	14	have	have	VBP
cord-287670-z6ckhkgg	136	15	been	be	VBN
cord-287670-z6ckhkgg	136	16	observed	observe	VBN
cord-287670-z6ckhkgg	136	17	in	in	IN
cord-287670-z6ckhkgg	136	18	global	global	JJ
cord-287670-z6ckhkgg	136	19	Ptx3	Ptx3	NNP
cord-287670-z6ckhkgg	136	20	À	à	NN
cord-287670-z6ckhkgg	136	21	/	/	SYM
cord-287670-z6ckhkgg	136	22	À	à	NN
cord-287670-z6ckhkgg	136	23	mice	mouse	NNS
cord-287670-z6ckhkgg	136	24	[	[	-LRB-
cord-287670-z6ckhkgg	136	25	29	29	CD
cord-287670-z6ckhkgg	136	26	,	,	,
cord-287670-z6ckhkgg	136	27	51	51	CD
cord-287670-z6ckhkgg	136	28	]	]	-RRB-
cord-287670-z6ckhkgg	136	29	.	.	.
cord-287670-z6ckhkgg	137	1	In	in	IN
cord-287670-z6ckhkgg	137	2	these	these	DT
cord-287670-z6ckhkgg	137	3	cases	case	NNS
cord-287670-z6ckhkgg	137	4	,	,	,
cord-287670-z6ckhkgg	137	5	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	137	6	was	be	VBD
cord-287670-z6ckhkgg	137	7	found	find	VBN
cord-287670-z6ckhkgg	137	8	to	to	TO
cord-287670-z6ckhkgg	137	9	exert	exert	VB
cord-287670-z6ckhkgg	137	10	a	a	DT
cord-287670-z6ckhkgg	137	11	protective	protective	JJ
cord-287670-z6ckhkgg	137	12	role	role	NN
cord-287670-z6ckhkgg	137	13	in	in	IN
cord-287670-z6ckhkgg	137	14	the	the	DT
cord-287670-z6ckhkgg	137	15	host	host	NN
cord-287670-z6ckhkgg	137	16	by	by	IN
cord-287670-z6ckhkgg	137	17	binding	bind	VBG
cord-287670-z6ckhkgg	137	18	human	human	JJ
cord-287670-z6ckhkgg	137	19	and	and	CC
cord-287670-z6ckhkgg	137	20	murine	murine	JJ
cord-287670-z6ckhkgg	137	21	CMV	CMV	NNP
cord-287670-z6ckhkgg	137	22	,	,	,
cord-287670-z6ckhkgg	137	23	which	which	WDT
cord-287670-z6ckhkgg	137	24	reduced	reduce	VBD
cord-287670-z6ckhkgg	137	25	viral	viral	JJ
cord-287670-z6ckhkgg	137	26	entry	entry	NN
cord-287670-z6ckhkgg	137	27	into	into	IN
cord-287670-z6ckhkgg	137	28	permissive	permissive	JJ
cord-287670-z6ckhkgg	137	29	cells	cell	NNS
cord-287670-z6ckhkgg	137	30	and	and	CC
cord-287670-z6ckhkgg	137	31	DCs	dc	NNS
cord-287670-z6ckhkgg	137	32	and	and	CC
cord-287670-z6ckhkgg	137	33	induced	induce	VBD
cord-287670-z6ckhkgg	137	34	interferon	interferon	NN
cord-287670-z6ckhkgg	137	35	regulatory	regulatory	JJ
cord-287670-z6ckhkgg	137	36	factor	factor	NN
cord-287670-z6ckhkgg	137	37	3	3	CD
cord-287670-z6ckhkgg	137	38	(	(	-LRB-
cord-287670-z6ckhkgg	137	39	IRF3	IRF3	NNP
cord-287670-z6ckhkgg	137	40	)	)	-RRB-
cord-287670-z6ckhkgg	137	41	activation	activation	NN
cord-287670-z6ckhkgg	137	42	in	in	RP
cord-287670-z6ckhkgg	137	43	in	in	IN
cord-287670-z6ckhkgg	137	44	vitro	vitro	FW
cord-287670-z6ckhkgg	137	45	experiments	experiment	NNS
cord-287670-z6ckhkgg	137	46	[	[	-LRB-
cord-287670-z6ckhkgg	137	47	51	51	CD
cord-287670-z6ckhkgg	137	48	]	]	-RRB-
cord-287670-z6ckhkgg	137	49	.	.	.
cord-287670-z6ckhkgg	138	1	Accordingly	accordingly	RB
cord-287670-z6ckhkgg	138	2	,	,	,
cord-287670-z6ckhkgg	138	3	intraperitoneal	intraperitoneal	JJ
cord-287670-z6ckhkgg	138	4	injection	injection	NN
cord-287670-z6ckhkgg	138	5	of	of	IN
cord-287670-z6ckhkgg	138	6	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	138	7	resulted	result	VBD
cord-287670-z6ckhkgg	138	8	in	in	IN
cord-287670-z6ckhkgg	138	9	therapeutic	therapeutic	JJ
cord-287670-z6ckhkgg	138	10	efficacy	efficacy	NN
cord-287670-z6ckhkgg	138	11	against	against	IN
cord-287670-z6ckhkgg	138	12	primary	primary	JJ
cord-287670-z6ckhkgg	138	13	CMV	CMV	NNP
cord-287670-z6ckhkgg	138	14	infection	infection	NN
cord-287670-z6ckhkgg	138	15	and	and	CC
cord-287670-z6ckhkgg	138	16	CMV	CMV	NNP
cord-287670-z6ckhkgg	138	17	reactivation	reactivation	NN
cord-287670-z6ckhkgg	138	18	in	in	IN
cord-287670-z6ckhkgg	138	19	hematopoietic	hematopoietic	JJ
cord-287670-z6ckhkgg	138	20	stem	stem	NN
cord-287670-z6ckhkgg	138	21	-	-	HYPH
cord-287670-z6ckhkgg	138	22	cell	cell	NN
cord-287670-z6ckhkgg	138	23	transplantation	transplantation	NN
cord-287670-z6ckhkgg	138	24	experiments	experiment	NNS
cord-287670-z6ckhkgg	138	25	in	in	IN
cord-287670-z6ckhkgg	138	26	mice	mouse	NNS
cord-287670-z6ckhkgg	138	27	,	,	,
cord-287670-z6ckhkgg	138	28	as	as	IN
cord-287670-z6ckhkgg	138	29	indicated	indicate	VBN
cord-287670-z6ckhkgg	138	30	by	by	IN
cord-287670-z6ckhkgg	138	31	the	the	DT
cord-287670-z6ckhkgg	138	32	observed	observed	JJ
cord-287670-z6ckhkgg	138	33	reduced	reduce	VBN
cord-287670-z6ckhkgg	138	34	viral	viral	JJ
cord-287670-z6ckhkgg	138	35	load	load	NN
cord-287670-z6ckhkgg	138	36	and	and	CC
cord-287670-z6ckhkgg	138	37	tissue	tissue	NN
cord-287670-z6ckhkgg	138	38	damage	damage	NN
cord-287670-z6ckhkgg	138	39	and	and	CC
cord-287670-z6ckhkgg	138	40	increased	increase	VBN
cord-287670-z6ckhkgg	138	41	animal	animal	NN
cord-287670-z6ckhkgg	138	42	survival	survival	NN
cord-287670-z6ckhkgg	138	43	[	[	-LRB-
cord-287670-z6ckhkgg	138	44	51	51	CD
cord-287670-z6ckhkgg	138	45	]	]	-RRB-
cord-287670-z6ckhkgg	138	46	.	.	.
cord-287670-z6ckhkgg	139	1	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	139	2	also	also	RB
cord-287670-z6ckhkgg	139	3	recognizes	recognize	VBZ
cord-287670-z6ckhkgg	139	4	specific	specific	JJ
cord-287670-z6ckhkgg	139	5	strains	strain	NNS
cord-287670-z6ckhkgg	139	6	of	of	IN
cord-287670-z6ckhkgg	139	7	H3N2-subtype	H3N2-subtype	NNP
cord-287670-z6ckhkgg	139	8	IAV	IAV	NNP
cord-287670-z6ckhkgg	139	9	by	by	IN
cord-287670-z6ckhkgg	139	10	interacting	interact	VBG
cord-287670-z6ckhkgg	139	11	with	with	IN
cord-287670-z6ckhkgg	139	12	viral	viral	JJ
cord-287670-z6ckhkgg	139	13	envelope	envelope	NN
cord-287670-z6ckhkgg	139	14	hemagglutinin	hemagglutinin	NN
cord-287670-z6ckhkgg	139	15	and	and	CC
cord-287670-z6ckhkgg	139	16	neuraminidase	neuraminidase	NN
cord-287670-z6ckhkgg	139	17	glycoproteins	glycoprotein	VBZ
cord-287670-z6ckhkgg	139	18	through	through	IN
cord-287670-z6ckhkgg	139	19	a	a	DT
cord-287670-z6ckhkgg	139	20	sialic	sialic	JJ
cord-287670-z6ckhkgg	139	21	acid	acid	NN
cord-287670-z6ckhkgg	139	22	residue	residue	NN
cord-287670-z6ckhkgg	139	23	on	on	IN
cord-287670-z6ckhkgg	139	24	its	-PRON-	PRP$
cord-287670-z6ckhkgg	139	25	glycosidic	glycosidic	JJ
cord-287670-z6ckhkgg	139	26	moiety	moiety	NN
cord-287670-z6ckhkgg	139	27	[	[	-LRB-
cord-287670-z6ckhkgg	139	28	29	29	CD
cord-287670-z6ckhkgg	139	29	]	]	-RRB-
cord-287670-z6ckhkgg	139	30	.	.	.
cord-287670-z6ckhkgg	140	1	In	in	IN
cord-287670-z6ckhkgg	140	2	this	this	DT
cord-287670-z6ckhkgg	140	3	manner	manner	NN
cord-287670-z6ckhkgg	140	4	,	,	,
cord-287670-z6ckhkgg	140	5	human	human	JJ
cord-287670-z6ckhkgg	140	6	and	and	CC
cord-287670-z6ckhkgg	140	7	murine	murine	JJ
cord-287670-z6ckhkgg	140	8	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	140	9	were	be	VBD
cord-287670-z6ckhkgg	140	10	shown	show	VBN
cord-287670-z6ckhkgg	140	11	to	to	TO
cord-287670-z6ckhkgg	140	12	act	act	VB
cord-287670-z6ckhkgg	140	13	as	as	IN
cord-287670-z6ckhkgg	140	14	'	'	''
cord-287670-z6ckhkgg	140	15	receptor	receptor	NN
cord-287670-z6ckhkgg	140	16	decoys	decoy	NNS
cord-287670-z6ckhkgg	140	17	'	'	''
cord-287670-z6ckhkgg	140	18	for	for	IN
cord-287670-z6ckhkgg	140	19	the	the	DT
cord-287670-z6ckhkgg	140	20	virus	virus	NN
cord-287670-z6ckhkgg	140	21	,	,	,
cord-287670-z6ckhkgg	140	22	preventing	prevent	VBG
cord-287670-z6ckhkgg	140	23	viral	viral	JJ
cord-287670-z6ckhkgg	140	24	spread	spread	NN
cord-287670-z6ckhkgg	140	25	and	and	CC
cord-287670-z6ckhkgg	140	26	infection	infection	NN
cord-287670-z6ckhkgg	140	27	by	by	IN
cord-287670-z6ckhkgg	140	28	specific	specific	JJ
cord-287670-z6ckhkgg	140	29	IAV	IAV	NNP
cord-287670-z6ckhkgg	140	30	strains	strain	NNS
cord-287670-z6ckhkgg	140	31	[	[	-LRB-
cord-287670-z6ckhkgg	140	32	29	29	CD
cord-287670-z6ckhkgg	140	33	]	]	-RRB-
cord-287670-z6ckhkgg	140	34	.	.	.
cord-287670-z6ckhkgg	141	1	In	in	IN
cord-287670-z6ckhkgg	141	2	line	line	NN
cord-287670-z6ckhkgg	141	3	with	with	IN
cord-287670-z6ckhkgg	141	4	these	these	DT
cord-287670-z6ckhkgg	141	5	data	datum	NNS
cord-287670-z6ckhkgg	141	6	,	,	,
cord-287670-z6ckhkgg	141	7	Ptx3	Ptx3	NNP
cord-287670-z6ckhkgg	141	8	À	à	NN
cord-287670-z6ckhkgg	141	9	/	/	SYM
cord-287670-z6ckhkgg	141	10	À	à	NN
cord-287670-z6ckhkgg	141	11	animals	animal	NNS
cord-287670-z6ckhkgg	141	12	were	be	VBD
cord-287670-z6ckhkgg	141	13	more	more	RBR
cord-287670-z6ckhkgg	141	14	susceptible	susceptible	JJ
cord-287670-z6ckhkgg	141	15	to	to	IN
cord-287670-z6ckhkgg	141	16	H3N2	H3N2	NNP
cord-287670-z6ckhkgg	141	17	infection	infection	NN
cord-287670-z6ckhkgg	141	18	than	than	IN
cord-287670-z6ckhkgg	141	19	wild	wild	JJ
cord-287670-z6ckhkgg	141	20	-	-	HYPH
cord-287670-z6ckhkgg	141	21	type	type	NN
cord-287670-z6ckhkgg	141	22	mice	mice	NN
cord-287670-z6ckhkgg	141	23	and	and	CC
cord-287670-z6ckhkgg	141	24	administration	administration	NN
cord-287670-z6ckhkgg	141	25	of	of	IN
cord-287670-z6ckhkgg	141	26	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	141	27	resulted	result	VBD
cord-287670-z6ckhkgg	141	28	in	in	IN
cord-287670-z6ckhkgg	141	29	a	a	DT
cord-287670-z6ckhkgg	141	30	protective	protective	JJ
cord-287670-z6ckhkgg	141	31	effect	effect	NN
cord-287670-z6ckhkgg	141	32	,	,	,
cord-287670-z6ckhkgg	141	33	as	as	IN
cord-287670-z6ckhkgg	141	34	evidenced	evidence	VBN
cord-287670-z6ckhkgg	141	35	by	by	IN
cord-287670-z6ckhkgg	141	36	increased	increase	VBN
cord-287670-z6ckhkgg	141	37	survival	survival	NN
cord-287670-z6ckhkgg	141	38	and	and	CC
cord-287670-z6ckhkgg	141	39	reduced	reduce	VBN
cord-287670-z6ckhkgg	141	40	viral	viral	JJ
cord-287670-z6ckhkgg	141	41	burden	burden	NN
cord-287670-z6ckhkgg	141	42	[	[	-LRB-
cord-287670-z6ckhkgg	141	43	29	29	CD
cord-287670-z6ckhkgg	141	44	]	]	-RRB-
cord-287670-z6ckhkgg	141	45	.	.	.
cord-287670-z6ckhkgg	142	1	By	by	IN
cord-287670-z6ckhkgg	142	2	contrast	contrast	NN
cord-287670-z6ckhkgg	142	3	,	,	,
cord-287670-z6ckhkgg	142	4	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	142	5	did	do	VBD
cord-287670-z6ckhkgg	142	6	not	not	RB
cord-287670-z6ckhkgg	142	7	result	result	VB
cord-287670-z6ckhkgg	142	8	in	in	IN
cord-287670-z6ckhkgg	142	9	antiviral	antiviral	JJ
cord-287670-z6ckhkgg	142	10	effects	effect	NNS
cord-287670-z6ckhkgg	142	11	against	against	IN
cord-287670-z6ckhkgg	142	12	seasonal	seasonal	JJ
cord-287670-z6ckhkgg	142	13	or	or	CC
cord-287670-z6ckhkgg	142	14	pandemic	pandemic	JJ
cord-287670-z6ckhkgg	142	15	H1N1	H1N1	NNP
cord-287670-z6ckhkgg	142	16	and	and	CC
cord-287670-z6ckhkgg	142	17	other	other	JJ
cord-287670-z6ckhkgg	142	18	H3N2	H3N2	NNP
cord-287670-z6ckhkgg	142	19	IAV	IAV	NNP
cord-287670-z6ckhkgg	142	20	strains	strain	NNS
cord-287670-z6ckhkgg	142	21	because	because	IN
cord-287670-z6ckhkgg	142	22	specific	specific	JJ
cord-287670-z6ckhkgg	142	23	amino	amino	NN
cord-287670-z6ckhkgg	142	24	acid	acid	NN
cord-287670-z6ckhkgg	142	25	residues	residue	NNS
cord-287670-z6ckhkgg	142	26	of	of	IN
cord-287670-z6ckhkgg	142	27	individual	individual	JJ
cord-287670-z6ckhkgg	142	28	viral	viral	JJ
cord-287670-z6ckhkgg	142	29	HA	HA	NNP
cord-287670-z6ckhkgg	142	30	sequences	sequence	NNS
cord-287670-z6ckhkgg	142	31	led	lead	VBD
cord-287670-z6ckhkgg	142	32	to	to	IN
cord-287670-z6ckhkgg	142	33	a	a	DT
cord-287670-z6ckhkgg	142	34	lack	lack	NN
cord-287670-z6ckhkgg	142	35	of	of	IN
cord-287670-z6ckhkgg	142	36	interacting	interact	VBG
cord-287670-z6ckhkgg	142	37	ability	ability	NN
cord-287670-z6ckhkgg	142	38	with	with	IN
cord-287670-z6ckhkgg	142	39	the	the	DT
cord-287670-z6ckhkgg	142	40	sialylated	sialylated	JJ
cord-287670-z6ckhkgg	142	41	residue	residue	NN
cord-287670-z6ckhkgg	142	42	of	of	IN
cord-287670-z6ckhkgg	142	43	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	142	44	[	[	-LRB-
cord-287670-z6ckhkgg	142	45	52,53	52,53	CD
cord-287670-z6ckhkgg	142	46	]	]	-RRB-
cord-287670-z6ckhkgg	142	47	.	.	.
cord-287670-z6ckhkgg	143	1	Hence	hence	RB
cord-287670-z6ckhkgg	143	2	,	,	,
cord-287670-z6ckhkgg	143	3	these	these	DT
cord-287670-z6ckhkgg	143	4	data	datum	NNS
cord-287670-z6ckhkgg	143	5	suggested	suggest	VBD
cord-287670-z6ckhkgg	143	6	selective	selective	JJ
cord-287670-z6ckhkgg	143	7	pressures	pressure	NNS
cord-287670-z6ckhkgg	143	8	on	on	IN
cord-287670-z6ckhkgg	143	9	HA	HA	NNP
cord-287670-z6ckhkgg	143	10	leading	lead	VBG
cord-287670-z6ckhkgg	143	11	to	to	IN
cord-287670-z6ckhkgg	143	12	viral	viral	JJ
cord-287670-z6ckhkgg	143	13	escape	escape	NN
cord-287670-z6ckhkgg	143	14	from	from	IN
cord-287670-z6ckhkgg	143	15	the	the	DT
cord-287670-z6ckhkgg	143	16	neutralizing	neutralize	VBG
cord-287670-z6ckhkgg	143	17	activity	activity	NN
cord-287670-z6ckhkgg	143	18	of	of	IN
cord-287670-z6ckhkgg	143	19	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	143	20	.	.	.
cord-287670-z6ckhkgg	144	1	Another	another	DT
cord-287670-z6ckhkgg	144	2	study	study	NN
cord-287670-z6ckhkgg	144	3	has	have	VBZ
cord-287670-z6ckhkgg	144	4	reported	report	VBN
cord-287670-z6ckhkgg	144	5	that	that	IN
cord-287670-z6ckhkgg	144	6	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	144	7	exerts	exert	VBZ
cord-287670-z6ckhkgg	144	8	a	a	DT
cord-287670-z6ckhkgg	144	9	protective	protective	JJ
cord-287670-z6ckhkgg	144	10	role	role	NN
cord-287670-z6ckhkgg	144	11	in	in	IN
cord-287670-z6ckhkgg	144	12	defense	defense	NN
cord-287670-z6ckhkgg	144	13	against	against	IN
cord-287670-z6ckhkgg	144	14	coronavirus	coronavirus	NN
cord-287670-z6ckhkgg	144	15	murine	murine	JJ
cord-287670-z6ckhkgg	144	16	hepatitis	hepatitis	NN
cord-287670-z6ckhkgg	144	17	virus	virus	NN
cord-287670-z6ckhkgg	145	1	strain	strain	NN
cord-287670-z6ckhkgg	145	2	1	1	CD
cord-287670-z6ckhkgg	145	3	(	(	-LRB-
cord-287670-z6ckhkgg	145	4	MHV-1	MHV-1	NNP
cord-287670-z6ckhkgg	145	5	)	)	-RRB-
cord-287670-z6ckhkgg	145	6	in	in	IN
cord-287670-z6ckhkgg	145	7	vitro	vitro	FW
cord-287670-z6ckhkgg	145	8	and	and	CC
cord-287670-z6ckhkgg	145	9	in	in	IN
cord-287670-z6ckhkgg	145	10	vivo	vivo	NNP
cord-287670-z6ckhkgg	145	11	[	[	-LRB-
cord-287670-z6ckhkgg	145	12	54	54	CD
cord-287670-z6ckhkgg	145	13	]	]	-RRB-
cord-287670-z6ckhkgg	145	14	.	.	.
cord-287670-z6ckhkgg	146	1	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	146	2	was	be	VBD
cord-287670-z6ckhkgg	146	3	shown	show	VBN
cord-287670-z6ckhkgg	146	4	to	to	TO
cord-287670-z6ckhkgg	146	5	bind	bind	VB
cord-287670-z6ckhkgg	146	6	to	to	IN
cord-287670-z6ckhkgg	146	7	MHV-1	MHV-1	NNP
cord-287670-z6ckhkgg	146	8	with	with	IN
cord-287670-z6ckhkgg	146	9	resulting	result	VBG
cord-287670-z6ckhkgg	146	10	reduced	reduce	VBN
cord-287670-z6ckhkgg	146	11	infectivity	infectivity	NN
cord-287670-z6ckhkgg	146	12	of	of	IN
cord-287670-z6ckhkgg	146	13	cells	cell	NNS
cord-287670-z6ckhkgg	146	14	in	in	IN
cord-287670-z6ckhkgg	146	15	culture	culture	NN
cord-287670-z6ckhkgg	146	16	.	.	.
cord-287670-z6ckhkgg	147	1	In	in	IN
cord-287670-z6ckhkgg	147	2	the	the	DT
cord-287670-z6ckhkgg	147	3	same	same	JJ
cord-287670-z6ckhkgg	147	4	study	study	NN
cord-287670-z6ckhkgg	147	5	,	,	,
cord-287670-z6ckhkgg	147	6	global	global	JJ
cord-287670-z6ckhkgg	147	7	PTX3-deficient	PTX3-deficient	NNP
cord-287670-z6ckhkgg	147	8	mice	mouse	NNS
cord-287670-z6ckhkgg	147	9	were	be	VBD
cord-287670-z6ckhkgg	147	10	more	more	RBR
cord-287670-z6ckhkgg	147	11	susceptible	susceptible	JJ
cord-287670-z6ckhkgg	147	12	than	than	IN
cord-287670-z6ckhkgg	147	13	their	-PRON-	PRP$
cord-287670-z6ckhkgg	147	14	wild	wild	JJ
cord-287670-z6ckhkgg	147	15	-	-	HYPH
cord-287670-z6ckhkgg	147	16	type	type	NN
cord-287670-z6ckhkgg	147	17	counterparts	counterpart	NNS
cord-287670-z6ckhkgg	147	18	to	to	IN
cord-287670-z6ckhkgg	147	19	MHV-1	MHV-1	NNP
cord-287670-z6ckhkgg	147	20	infection	infection	NN
cord-287670-z6ckhkgg	147	21	[	[	-LRB-
cord-287670-z6ckhkgg	147	22	54	54	CD
cord-287670-z6ckhkgg	147	23	]	]	-RRB-
cord-287670-z6ckhkgg	147	24	.	.	.
cord-287670-z6ckhkgg	148	1	Administration	Administration	NNP
cord-287670-z6ckhkgg	148	2	of	of	IN
cord-287670-z6ckhkgg	148	3	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	148	4	led	lead	VBD
cord-287670-z6ckhkgg	148	5	to	to	IN
cord-287670-z6ckhkgg	148	6	protection	protection	NN
cord-287670-z6ckhkgg	148	7	against	against	IN
cord-287670-z6ckhkgg	148	8	MHV-1	MHV-1	NNP
cord-287670-z6ckhkgg	148	9	,	,	,
cord-287670-z6ckhkgg	148	10	because	because	IN
cord-287670-z6ckhkgg	148	11	reduced	reduce	VBN
cord-287670-z6ckhkgg	148	12	lung	lung	NN
cord-287670-z6ckhkgg	148	13	injury	injury	NN
cord-287670-z6ckhkgg	148	14	and	and	CC
cord-287670-z6ckhkgg	148	15	inflammation	inflammation	NN
cord-287670-z6ckhkgg	148	16	and	and	CC
cord-287670-z6ckhkgg	148	17	accelerated	accelerate	VBN
cord-287670-z6ckhkgg	148	18	viral	viral	JJ
cord-287670-z6ckhkgg	148	19	clearance	clearance	NN
cord-287670-z6ckhkgg	148	20	were	be	VBD
cord-287670-z6ckhkgg	148	21	observed	observe	VBN
cord-287670-z6ckhkgg	148	22	[	[	-LRB-
cord-287670-z6ckhkgg	148	23	54	54	CD
cord-287670-z6ckhkgg	148	24	]	]	-RRB-
cord-287670-z6ckhkgg	148	25	.	.	.
cord-287670-z6ckhkgg	149	1	Although	although	IN
cord-287670-z6ckhkgg	149	2	collectively	collectively	RB
cord-287670-z6ckhkgg	149	3	these	these	DT
cord-287670-z6ckhkgg	149	4	results	result	NNS
cord-287670-z6ckhkgg	149	5	have	have	VBP
cord-287670-z6ckhkgg	149	6	demonstrated	demonstrate	VBN
cord-287670-z6ckhkgg	149	7	a	a	DT
cord-287670-z6ckhkgg	149	8	protective	protective	JJ
cord-287670-z6ckhkgg	149	9	role	role	NN
cord-287670-z6ckhkgg	149	10	of	of	IN
cord-287670-z6ckhkgg	149	11	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	149	12	during	during	IN
cord-287670-z6ckhkgg	149	13	microbial	microbial	JJ
cord-287670-z6ckhkgg	149	14	invasion	invasion	NN
cord-287670-z6ckhkgg	149	15	,	,	,
cord-287670-z6ckhkgg	149	16	there	there	EX
cord-287670-z6ckhkgg	149	17	are	be	VBP
cord-287670-z6ckhkgg	149	18	other	other	JJ
cord-287670-z6ckhkgg	149	19	studies	study	NNS
cord-287670-z6ckhkgg	149	20	where	where	WRB
cord-287670-z6ckhkgg	149	21	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	149	22	has	have	VBZ
cord-287670-z6ckhkgg	149	23	been	be	VBN
cord-287670-z6ckhkgg	149	24	found	find	VBN
cord-287670-z6ckhkgg	149	25	to	to	TO
cord-287670-z6ckhkgg	149	26	promote	promote	VB
cord-287670-z6ckhkgg	149	27	immunopathology	immunopathology	NN
cord-287670-z6ckhkgg	149	28	in	in	IN
cord-287670-z6ckhkgg	149	29	a	a	DT
cord-287670-z6ckhkgg	149	30	context	context	NN
cord-287670-z6ckhkgg	149	31	-	-	HYPH
cord-287670-z6ckhkgg	149	32	specific	specific	JJ
cord-287670-z6ckhkgg	149	33	manner	manner	NN
cord-287670-z6ckhkgg	149	34	(	(	-LRB-
cord-287670-z6ckhkgg	149	35	Figure	figure	NN
cord-287670-z6ckhkgg	149	36	2	2	CD
cord-287670-z6ckhkgg	149	37	)	)	-RRB-
cord-287670-z6ckhkgg	149	38	.	.	.
cord-287670-z6ckhkgg	150	1	In	in	IN
cord-287670-z6ckhkgg	150	2	a	a	DT
cord-287670-z6ckhkgg	150	3	model	model	NN
cord-287670-z6ckhkgg	150	4	of	of	IN
cord-287670-z6ckhkgg	150	5	K.	K.	NNP
cord-287670-z6ckhkgg	150	6	pneumoniae	pneumoniae	NN
cord-287670-z6ckhkgg	150	7	infection	infection	NN
cord-287670-z6ckhkgg	150	8	in	in	IN
cord-287670-z6ckhkgg	150	9	mice	mouse	NNS
cord-287670-z6ckhkgg	150	10	,	,	,
cord-287670-z6ckhkgg	150	11	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	150	12	overexpression	overexpression	NN
cord-287670-z6ckhkgg	150	13	was	be	VBD
cord-287670-z6ckhkgg	150	14	reported	report	VBN
cord-287670-z6ckhkgg	150	15	to	to	TO
cord-287670-z6ckhkgg	150	16	play	play	VB
cord-287670-z6ckhkgg	150	17	antagonistic	antagonistic	JJ
cord-287670-z6ckhkgg	150	18	roles	role	NNS
cord-287670-z6ckhkgg	150	19	depending	depend	VBG
cord-287670-z6ckhkgg	150	20	on	on	IN
cord-287670-z6ckhkgg	150	21	the	the	DT
cord-287670-z6ckhkgg	150	22	bacterial	bacterial	JJ
cord-287670-z6ckhkgg	150	23	concentrations	concentration	NNS
cord-287670-z6ckhkgg	150	24	used	use	VBN
cord-287670-z6ckhkgg	150	25	to	to	TO
cord-287670-z6ckhkgg	150	26	infect	infect	VB
cord-287670-z6ckhkgg	150	27	animals	animal	NNS
cord-287670-z6ckhkgg	150	28	[	[	-LRB-
cord-287670-z6ckhkgg	150	29	17	17	CD
cord-287670-z6ckhkgg	150	30	]	]	-RRB-
cord-287670-z6ckhkgg	150	31	.	.	.
cord-287670-z6ckhkgg	151	1	With	with	IN
cord-287670-z6ckhkgg	151	2	high	high	JJ
cord-287670-z6ckhkgg	151	3	bacterial	bacterial	JJ
cord-287670-z6ckhkgg	151	4	loads	load	NNS
cord-287670-z6ckhkgg	151	5	,	,	,
cord-287670-z6ckhkgg	151	6	transgenic	transgenic	JJ
cord-287670-z6ckhkgg	151	7	mice	mouse	NNS
cord-287670-z6ckhkgg	151	8	expressing	express	VBG
cord-287670-z6ckhkgg	151	9	multiple	multiple	JJ
cord-287670-z6ckhkgg	151	10	copies	copy	NNS
cord-287670-z6ckhkgg	151	11	of	of	IN
cord-287670-z6ckhkgg	151	12	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	151	13	under	under	IN
cord-287670-z6ckhkgg	151	14	the	the	DT
cord-287670-z6ckhkgg	151	15	control	control	NN
cord-287670-z6ckhkgg	151	16	of	of	IN
cord-287670-z6ckhkgg	151	17	its	-PRON-	PRP$
cord-287670-z6ckhkgg	151	18	own	own	JJ
cord-287670-z6ckhkgg	151	19	promoter	promoter	NN
cord-287670-z6ckhkgg	151	20	displayed	display	VBD
cord-287670-z6ckhkgg	151	21	faster	fast	JJR
cord-287670-z6ckhkgg	151	22	lethality	lethality	NN
cord-287670-z6ckhkgg	151	23	,	,	,
cord-287670-z6ckhkgg	151	24	reduced	reduce	VBN
cord-287670-z6ckhkgg	151	25	lung	lung	NN
cord-287670-z6ckhkgg	151	26	infiltration	infiltration	NN
cord-287670-z6ckhkgg	151	27	of	of	IN
cord-287670-z6ckhkgg	151	28	neutrophils	neutrophil	NNS
cord-287670-z6ckhkgg	151	29	,	,	,
cord-287670-z6ckhkgg	151	30	and	and	CC
cord-287670-z6ckhkgg	151	31	increased	increase	VBN
cord-287670-z6ckhkgg	151	32	bacterial	bacterial	JJ
cord-287670-z6ckhkgg	151	33	dissemination	dissemination	NN
cord-287670-z6ckhkgg	151	34	in	in	IN
cord-287670-z6ckhkgg	151	35	blood	blood	NN
cord-287670-z6ckhkgg	151	36	compared	compare	VBN
cord-287670-z6ckhkgg	151	37	with	with	IN
cord-287670-z6ckhkgg	151	38	wild	wild	JJ
cord-287670-z6ckhkgg	151	39	-	-	HYPH
cord-287670-z6ckhkgg	151	40	type	type	NN
cord-287670-z6ckhkgg	151	41	animals	animal	NNS
cord-287670-z6ckhkgg	151	42	[	[	-LRB-
cord-287670-z6ckhkgg	151	43	17	17	CD
cord-287670-z6ckhkgg	151	44	]	]	-RRB-
cord-287670-z6ckhkgg	151	45	.	.	.
cord-287670-z6ckhkgg	152	1	By	by	IN
cord-287670-z6ckhkgg	152	2	contrast	contrast	NN
cord-287670-z6ckhkgg	152	3	,	,	,
cord-287670-z6ckhkgg	152	4	with	with	IN
cord-287670-z6ckhkgg	152	5	lower	low	JJR
cord-287670-z6ckhkgg	152	6	K.	K.	NNP
cord-287670-z6ckhkgg	152	7	pneumonia	pneumonia	NN
cord-287670-z6ckhkgg	152	8	pulmonary	pulmonary	NN
cord-287670-z6ckhkgg	152	9	inocula	inocula	JJ
cord-287670-z6ckhkgg	152	10	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	152	11	overexpression	overexpression	NN
cord-287670-z6ckhkgg	152	12	conferred	confer	VBD
cord-287670-z6ckhkgg	152	13	protection	protection	NN
cord-287670-z6ckhkgg	152	14	on	on	IN
cord-287670-z6ckhkgg	152	15	mice	mouse	NNS
cord-287670-z6ckhkgg	152	16	by	by	IN
cord-287670-z6ckhkgg	152	17	increasing	increase	VBG
cord-287670-z6ckhkgg	152	18	the	the	DT
cord-287670-z6ckhkgg	152	19	expression	expression	NN
cord-287670-z6ckhkgg	152	20	of	of	IN
cord-287670-z6ckhkgg	152	21	proinflammatory	proinflammatory	JJ
cord-287670-z6ckhkgg	152	22	cytokines	cytokine	NNS
cord-287670-z6ckhkgg	152	23	and	and	CC
cord-287670-z6ckhkgg	152	24	the	the	DT
cord-287670-z6ckhkgg	152	25	recruitment	recruitment	NN
cord-287670-z6ckhkgg	152	26	of	of	IN
cord-287670-z6ckhkgg	152	27	neutrophils	neutrophil	NNS
cord-287670-z6ckhkgg	152	28	into	into	IN
cord-287670-z6ckhkgg	152	29	lung	lung	NN
cord-287670-z6ckhkgg	152	30	tissues	tissue	NNS
cord-287670-z6ckhkgg	152	31	and	and	CC
cord-287670-z6ckhkgg	152	32	by	by	IN
cord-287670-z6ckhkgg	152	33	promoting	promote	VBG
cord-287670-z6ckhkgg	152	34	bacterial	bacterial	JJ
cord-287670-z6ckhkgg	152	35	phagocytosis	phagocytosis	NN
cord-287670-z6ckhkgg	152	36	[	[	-LRB-
cord-287670-z6ckhkgg	152	37	17	17	CD
cord-287670-z6ckhkgg	152	38	]	]	-RRB-
cord-287670-z6ckhkgg	152	39	.	.	.
cord-287670-z6ckhkgg	153	1	KpOmpA	KpOmpA	NNP
cord-287670-z6ckhkgg	153	2	,	,	,
cord-287670-z6ckhkgg	153	3	a	a	DT
cord-287670-z6ckhkgg	153	4	conserved	conserved	JJ
cord-287670-z6ckhkgg	153	5	major	major	JJ
cord-287670-z6ckhkgg	153	6	component	component	NN
cord-287670-z6ckhkgg	153	7	of	of	IN
cord-287670-z6ckhkgg	153	8	the	the	DT
cord-287670-z6ckhkgg	153	9	outer	outer	JJ
cord-287670-z6ckhkgg	153	10	membrane	membrane	NN
cord-287670-z6ckhkgg	153	11	of	of	IN
cord-287670-z6ckhkgg	153	12	Enterobacteriaceae	Enterobacteriaceae	NNP
cord-287670-z6ckhkgg	153	13	,	,	,
cord-287670-z6ckhkgg	153	14	is	be	VBZ
cord-287670-z6ckhkgg	153	15	one	one	CD
cord-287670-z6ckhkgg	153	16	of	of	IN
cord-287670-z6ckhkgg	153	17	the	the	DT
cord-287670-z6ckhkgg	153	18	few	few	JJ
cord-287670-z6ckhkgg	153	19	characterized	characterize	VBN
cord-287670-z6ckhkgg	153	20	microbial	microbial	JJ
cord-287670-z6ckhkgg	153	21	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	153	22	ligands	ligand	NNS
cord-287670-z6ckhkgg	153	23	[	[	-LRB-
cord-287670-z6ckhkgg	153	24	46	46	CD
cord-287670-z6ckhkgg	153	25	]	]	-RRB-
cord-287670-z6ckhkgg	153	26	.	.	.
cord-287670-z6ckhkgg	154	1	In	in	IN
cord-287670-z6ckhkgg	154	2	the	the	DT
cord-287670-z6ckhkgg	154	3	mouse	mouse	NN
cord-287670-z6ckhkgg	154	4	air	air	NN
cord-287670-z6ckhkgg	154	5	pouch	pouch	NN
cord-287670-z6ckhkgg	154	6	and	and	CC
cord-287670-z6ckhkgg	154	7	footpad	footpad	NN
cord-287670-z6ckhkgg	154	8	swelling	swelling	NN
cord-287670-z6ckhkgg	154	9	model	model	NN
cord-287670-z6ckhkgg	154	10	,	,	,
cord-287670-z6ckhkgg	154	11	KpOmpA	KpOmpA	NNP
cord-287670-z6ckhkgg	154	12	has	have	VBZ
cord-287670-z6ckhkgg	154	13	been	be	VBN
cord-287670-z6ckhkgg	154	14	found	find	VBN
cord-287670-z6ckhkgg	154	15	to	to	TO
cord-287670-z6ckhkgg	154	16	induce	induce	VB
cord-287670-z6ckhkgg	154	17	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	154	18	production	production	NN
cord-287670-z6ckhkgg	154	19	and	and	CC
cord-287670-z6ckhkgg	154	20	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	154	21	,	,	,
cord-287670-z6ckhkgg	154	22	in	in	IN
cord-287670-z6ckhkgg	154	23	turn	turn	NN
cord-287670-z6ckhkgg	154	24	,	,	,
cord-287670-z6ckhkgg	154	25	can	can	MD
cord-287670-z6ckhkgg	154	26	amplify	amplify	VB
cord-287670-z6ckhkgg	154	27	TLR2-dependent	TLR2-dependent	NNP
cord-287670-z6ckhkgg	154	28	inflammatory	inflammatory	JJ
cord-287670-z6ckhkgg	154	29	responses	response	NNS
cord-287670-z6ckhkgg	154	30	such	such	JJ
cord-287670-z6ckhkgg	154	31	as	as	IN
cord-287670-z6ckhkgg	154	32	leukocyte	leukocyte	NN
cord-287670-z6ckhkgg	154	33	recruitment	recruitment	NN
cord-287670-z6ckhkgg	154	34	induced	induce	VBN
cord-287670-z6ckhkgg	154	35	following	follow	VBG
cord-287670-z6ckhkgg	154	36	KpOmpA	KpOmpA	NNP
cord-287670-z6ckhkgg	154	37	recognition	recognition	NN
cord-287670-z6ckhkgg	154	38	of	of	IN
cord-287670-z6ckhkgg	154	39	the	the	DT
cord-287670-z6ckhkgg	154	40	scavenger	scavenger	NN
cord-287670-z6ckhkgg	154	41	receptors	receptor	NNS
cord-287670-z6ckhkgg	154	42	lectin	lectin	NN
cord-287670-z6ckhkgg	154	43	-	-	HYPH
cord-287670-z6ckhkgg	154	44	like	like	JJ
cord-287670-z6ckhkgg	154	45	oxidized	oxidized	JJ
cord-287670-z6ckhkgg	154	46	lowdensity	lowdensity	NN
cord-287670-z6ckhkgg	154	47	lipoprotein	lipoprotein	NN
cord-287670-z6ckhkgg	154	48	receptor-1	receptor-1	NNP
cord-287670-z6ckhkgg	154	49	(	(	-LRB-
cord-287670-z6ckhkgg	154	50	LOX-1	LOX-1	NNP
cord-287670-z6ckhkgg	154	51	)	)	-RRB-
cord-287670-z6ckhkgg	154	52	and	and	CC
cord-287670-z6ckhkgg	154	53	scavenger	scavenger	NN
cord-287670-z6ckhkgg	154	54	receptor	receptor	NN
cord-287670-z6ckhkgg	154	55	expressed	express	VBN
cord-287670-z6ckhkgg	154	56	by	by	IN
cord-287670-z6ckhkgg	154	57	ECs	ec	NNS
cord-287670-z6ckhkgg	154	58	I	I	NNP
cord-287670-z6ckhkgg	154	59	(	(	-LRB-
cord-287670-z6ckhkgg	154	60	SREC	SREC	NNP
cord-287670-z6ckhkgg	154	61	-	-	HYPH
cord-287670-z6ckhkgg	154	62	I	I	NNP
cord-287670-z6ckhkgg	154	63	)	)	-RRB-
cord-287670-z6ckhkgg	154	64	[	[	-LRB-
cord-287670-z6ckhkgg	154	65	46	46	CD
cord-287670-z6ckhkgg	154	66	]	]	-RRB-
cord-287670-z6ckhkgg	154	67	.	.	.
cord-287670-z6ckhkgg	155	1	These	these	DT
cord-287670-z6ckhkgg	155	2	results	result	NNS
cord-287670-z6ckhkgg	155	3	suggest	suggest	VBP
cord-287670-z6ckhkgg	155	4	that	that	IN
cord-287670-z6ckhkgg	155	5	K.	K.	NNP
cord-287670-z6ckhkgg	155	6	pneumoniae	pneumoniae	NN
cord-287670-z6ckhkgg	155	7	-	-	HYPH
cord-287670-z6ckhkgg	155	8	induced	induce	VBN
cord-287670-z6ckhkgg	155	9	,	,	,
cord-287670-z6ckhkgg	155	10	amplified	amplify	VBD
cord-287670-z6ckhkgg	155	11	PTX3-dependent	PTX3-dependent	NNP
cord-287670-z6ckhkgg	155	12	inflammatory	inflammatory	JJ
cord-287670-z6ckhkgg	155	13	responses	response	NNS
cord-287670-z6ckhkgg	155	14	either	either	CC
cord-287670-z6ckhkgg	155	15	play	play	VBP
cord-287670-z6ckhkgg	155	16	protective	protective	JJ
cord-287670-z6ckhkgg	155	17	roles	role	NNS
cord-287670-z6ckhkgg	155	18	for	for	IN
cord-287670-z6ckhkgg	155	19	the	the	DT
cord-287670-z6ckhkgg	155	20	host	host	NN
cord-287670-z6ckhkgg	155	21	or	or	CC
cord-287670-z6ckhkgg	155	22	might	may	MD
cord-287670-z6ckhkgg	155	23	contribute	contribute	VB
cord-287670-z6ckhkgg	155	24	to	to	IN
cord-287670-z6ckhkgg	155	25	immunopathology	immunopathology	NN
cord-287670-z6ckhkgg	155	26	,	,	,
cord-287670-z6ckhkgg	155	27	depending	depend	VBG
cord-287670-z6ckhkgg	155	28	on	on	IN
cord-287670-z6ckhkgg	155	29	microbial	microbial	JJ
cord-287670-z6ckhkgg	155	30	load	load	NN
cord-287670-z6ckhkgg	155	31	.	.	.
cord-287670-z6ckhkgg	156	1	This	this	DT
cord-287670-z6ckhkgg	156	2	underlies	underlie	VBZ
cord-287670-z6ckhkgg	156	3	the	the	DT
cord-287670-z6ckhkgg	156	4	relevance	relevance	NN
cord-287670-z6ckhkgg	156	5	of	of	IN
cord-287670-z6ckhkgg	156	6	balanced	balanced	JJ
cord-287670-z6ckhkgg	156	7	and	and	CC
cord-287670-z6ckhkgg	156	8	finely	finely	RB
cord-287670-z6ckhkgg	156	9	tuned	tune	VBN
cord-287670-z6ckhkgg	156	10	inflammatory	inflammatory	JJ
cord-287670-z6ckhkgg	156	11	responses	response	NNS
cord-287670-z6ckhkgg	156	12	and	and	CC
cord-287670-z6ckhkgg	156	13	innate	innate	JJ
cord-287670-z6ckhkgg	156	14	resistance	resistance	NN
cord-287670-z6ckhkgg	156	15	to	to	IN
cord-287670-z6ckhkgg	156	16	this	this	DT
cord-287670-z6ckhkgg	156	17	type	type	NN
cord-287670-z6ckhkgg	156	18	of	of	IN
cord-287670-z6ckhkgg	156	19	bacterial	bacterial	JJ
cord-287670-z6ckhkgg	156	20	infection	infection	NN
cord-287670-z6ckhkgg	156	21	(	(	-LRB-
cord-287670-z6ckhkgg	156	22	Figure	figure	NN
cord-287670-z6ckhkgg	156	23	2	2	CD
cord-287670-z6ckhkgg	156	24	)	)	-RRB-
cord-287670-z6ckhkgg	156	25	.	.	.
cord-287670-z6ckhkgg	157	1	Although	although	IN
cord-287670-z6ckhkgg	157	2	future	future	JJ
cord-287670-z6ckhkgg	157	3	research	research	NN
cord-287670-z6ckhkgg	157	4	might	may	MD
cord-287670-z6ckhkgg	157	5	further	further	RB
cord-287670-z6ckhkgg	157	6	clarify	clarify	VB
cord-287670-z6ckhkgg	157	7	whether	whether	IN
cord-287670-z6ckhkgg	157	8	these	these	DT
cord-287670-z6ckhkgg	157	9	type	type	NN
cord-287670-z6ckhkgg	157	10	of	of	IN
cord-287670-z6ckhkgg	157	11	findings	finding	NNS
cord-287670-z6ckhkgg	157	12	could	could	MD
cord-287670-z6ckhkgg	157	13	be	be	VB
cord-287670-z6ckhkgg	157	14	influenced	influence	VBN
cord-287670-z6ckhkgg	157	15	by	by	IN
cord-287670-z6ckhkgg	157	16	particular	particular	JJ
cord-287670-z6ckhkgg	157	17	experimental	experimental	JJ
cord-287670-z6ckhkgg	157	18	conditions	condition	NNS
cord-287670-z6ckhkgg	157	19	,	,	,
cord-287670-z6ckhkgg	157	20	or	or	CC
cord-287670-z6ckhkgg	157	21	whether	whether	IN
cord-287670-z6ckhkgg	157	22	the	the	DT
cord-287670-z6ckhkgg	157	23	results	result	NNS
cord-287670-z6ckhkgg	157	24	hold	hold	VBP
cord-287670-z6ckhkgg	157	25	true	true	JJ
cord-287670-z6ckhkgg	157	26	for	for	IN
cord-287670-z6ckhkgg	157	27	different	different	JJ
cord-287670-z6ckhkgg	157	28	pathogen	pathogen	NN
cord-287670-z6ckhkgg	157	29	infections	infection	NNS
cord-287670-z6ckhkgg	157	30	,	,	,
cord-287670-z6ckhkgg	157	31	the	the	DT
cord-287670-z6ckhkgg	157	32	fact	fact	NN
cord-287670-z6ckhkgg	157	33	remains	remain	VBZ
cord-287670-z6ckhkgg	157	34	that	that	IN
cord-287670-z6ckhkgg	157	35	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	157	36	plays	play	VBZ
cord-287670-z6ckhkgg	157	37	a	a	DT
cord-287670-z6ckhkgg	157	38	complex	complex	JJ
cord-287670-z6ckhkgg	157	39	role	role	NN
cord-287670-z6ckhkgg	157	40	in	in	IN
cord-287670-z6ckhkgg	157	41	immunoregulation	immunoregulation	NN
cord-287670-z6ckhkgg	157	42	.	.	.
cord-287670-z6ckhkgg	158	1	Furthermore	furthermore	RB
cord-287670-z6ckhkgg	158	2	,	,	,
cord-287670-z6ckhkgg	158	3	a	a	DT
cord-287670-z6ckhkgg	158	4	pathogenic	pathogenic	JJ
cord-287670-z6ckhkgg	158	5	role	role	NN
cord-287670-z6ckhkgg	158	6	of	of	IN
cord-287670-z6ckhkgg	158	7	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	158	8	has	have	VBZ
cord-287670-z6ckhkgg	158	9	been	be	VBN
cord-287670-z6ckhkgg	158	10	demonstrated	demonstrate	VBN
cord-287670-z6ckhkgg	158	11	in	in	IN
cord-287670-z6ckhkgg	158	12	arthritogenic	arthritogenic	NNP
cord-287670-z6ckhkgg	158	13	alphavirus	alphavirus	NNP
cord-287670-z6ckhkgg	158	14	infections	infection	NNS
cord-287670-z6ckhkgg	158	15	induced	induce	VBN
cord-287670-z6ckhkgg	158	16	by	by	IN
cord-287670-z6ckhkgg	158	17	Chikungunya	Chikungunya	NNP
cord-287670-z6ckhkgg	158	18	virus	virus	NN
cord-287670-z6ckhkgg	158	19	(	(	-LRB-
cord-287670-z6ckhkgg	158	20	CHIKV	CHIKV	NNP
cord-287670-z6ckhkgg	158	21	)	)	-RRB-
cord-287670-z6ckhkgg	158	22	and	and	CC
cord-287670-z6ckhkgg	158	23	Ross	Ross	NNP
cord-287670-z6ckhkgg	158	24	River	River	NNP
cord-287670-z6ckhkgg	158	25	virus	virus	NN
cord-287670-z6ckhkgg	158	26	(	(	-LRB-
cord-287670-z6ckhkgg	158	27	RRV	RRV	NNP
cord-287670-z6ckhkgg	158	28	)	)	-RRB-
cord-287670-z6ckhkgg	159	1	[	[	-LRB-
cord-287670-z6ckhkgg	159	2	55	55	CD
cord-287670-z6ckhkgg	159	3	]	]	-RRB-
cord-287670-z6ckhkgg	159	4	(	(	-LRB-
cord-287670-z6ckhkgg	159	5	Figure	figure	NN
cord-287670-z6ckhkgg	159	6	2	2	CD
cord-287670-z6ckhkgg	159	7	)	)	-RRB-
cord-287670-z6ckhkgg	159	8	.	.	.
cord-287670-z6ckhkgg	160	1	For	for	IN
cord-287670-z6ckhkgg	160	2	instance	instance	NN
cord-287670-z6ckhkgg	160	3	,	,	,
cord-287670-z6ckhkgg	160	4	the	the	DT
cord-287670-z6ckhkgg	160	5	expression	expression	NN
cord-287670-z6ckhkgg	160	6	of	of	IN
cord-287670-z6ckhkgg	160	7	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	160	8	mRNA	mRNA	NNP
cord-287670-z6ckhkgg	160	9	in	in	IN
cord-287670-z6ckhkgg	160	10	peripheral	peripheral	JJ
cord-287670-z6ckhkgg	160	11	blood	blood	NN
cord-287670-z6ckhkgg	160	12	leukocytes	leukocyte	NNS
cord-287670-z6ckhkgg	160	13	and	and	CC
cord-287670-z6ckhkgg	160	14	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	160	15	levels	level	NNS
cord-287670-z6ckhkgg	160	16	in	in	IN
cord-287670-z6ckhkgg	160	17	serum	serum	NN
cord-287670-z6ckhkgg	160	18	have	have	VBP
cord-287670-z6ckhkgg	160	19	been	be	VBN
cord-287670-z6ckhkgg	160	20	found	find	VBN
cord-287670-z6ckhkgg	160	21	to	to	TO
cord-287670-z6ckhkgg	160	22	be	be	VB
cord-287670-z6ckhkgg	160	23	increased	increase	VBN
cord-287670-z6ckhkgg	160	24	during	during	IN
cord-287670-z6ckhkgg	160	25	the	the	DT
cord-287670-z6ckhkgg	160	26	acute	acute	JJ
cord-287670-z6ckhkgg	160	27	phase	phase	NN
cord-287670-z6ckhkgg	160	28	of	of	IN
cord-287670-z6ckhkgg	160	29	alphavirus	alphavirus	NN
cord-287670-z6ckhkgg	160	30	infection	infection	NN
cord-287670-z6ckhkgg	160	31	both	both	CC
cord-287670-z6ckhkgg	160	32	in	in	IN
cord-287670-z6ckhkgg	160	33	patients	patient	NNS
cord-287670-z6ckhkgg	160	34	and	and	CC
cord-287670-z6ckhkgg	160	35	in	in	IN
cord-287670-z6ckhkgg	160	36	animal	animal	NN
cord-287670-z6ckhkgg	160	37	models	model	NNS
cord-287670-z6ckhkgg	160	38	[	[	-LRB-
cord-287670-z6ckhkgg	160	39	55	55	CD
cord-287670-z6ckhkgg	160	40	]	]	-RRB-
cord-287670-z6ckhkgg	160	41	.	.	.
cord-287670-z6ckhkgg	161	1	Increased	increase	VBN
cord-287670-z6ckhkgg	161	2	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	161	3	expression	expression	NN
cord-287670-z6ckhkgg	161	4	was	be	VBD
cord-287670-z6ckhkgg	161	5	associated	associate	VBN
cord-287670-z6ckhkgg	161	6	not	not	RB
cord-287670-z6ckhkgg	161	7	only	only	RB
cord-287670-z6ckhkgg	161	8	with	with	IN
cord-287670-z6ckhkgg	161	9	enhanced	enhance	VBN
cord-287670-z6ckhkgg	161	10	viral	viral	JJ
cord-287670-z6ckhkgg	161	11	load	load	NN
cord-287670-z6ckhkgg	161	12	but	but	CC
cord-287670-z6ckhkgg	161	13	also	also	RB
cord-287670-z6ckhkgg	161	14	with	with	IN
cord-287670-z6ckhkgg	161	15	disease	disease	NN
cord-287670-z6ckhkgg	161	16	severity	severity	NN
cord-287670-z6ckhkgg	161	17	based	base	VBN
cord-287670-z6ckhkgg	161	18	on	on	IN
cord-287670-z6ckhkgg	161	19	temperature	temperature	NN
cord-287670-z6ckhkgg	161	20	,	,	,
cord-287670-z6ckhkgg	161	21	pulse	pulse	NN
cord-287670-z6ckhkgg	161	22	rate	rate	NN
cord-287670-z6ckhkgg	161	23	,	,	,
cord-287670-z6ckhkgg	161	24	and	and	CC
cord-287670-z6ckhkgg	161	25	platelet	platelet	NN
cord-287670-z6ckhkgg	161	26	counts	count	NNS
cord-287670-z6ckhkgg	161	27	[	[	-LRB-
cord-287670-z6ckhkgg	161	28	55	55	CD
cord-287670-z6ckhkgg	161	29	]	]	-RRB-
cord-287670-z6ckhkgg	161	30	.	.	.
cord-287670-z6ckhkgg	162	1	A	a	DT
cord-287670-z6ckhkgg	162	2	murine	murine	JJ
cord-287670-z6ckhkgg	162	3	model	model	NN
cord-287670-z6ckhkgg	162	4	of	of	IN
cord-287670-z6ckhkgg	162	5	acute	acute	JJ
cord-287670-z6ckhkgg	162	6	RRV	RRV	NNP
cord-287670-z6ckhkgg	162	7	infection	infection	NN
cord-287670-z6ckhkgg	162	8	revealed	reveal	VBD
cord-287670-z6ckhkgg	162	9	a	a	DT
cord-287670-z6ckhkgg	162	10	delay	delay	NN
cord-287670-z6ckhkgg	162	11	in	in	IN
cord-287670-z6ckhkgg	162	12	disease	disease	NN
cord-287670-z6ckhkgg	162	13	progression	progression	NN
cord-287670-z6ckhkgg	162	14	,	,	,
cord-287670-z6ckhkgg	162	15	as	as	IN
cord-287670-z6ckhkgg	162	16	shown	show	VBN
cord-287670-z6ckhkgg	162	17	by	by	IN
cord-287670-z6ckhkgg	162	18	increased	increase	VBN
cord-287670-z6ckhkgg	162	19	animal	animal	NN
cord-287670-z6ckhkgg	162	20	strength	strength	NN
cord-287670-z6ckhkgg	162	21	and	and	CC
cord-287670-z6ckhkgg	162	22	hind	hind	NN
cord-287670-z6ckhkgg	162	23	-	-	HYPH
cord-287670-z6ckhkgg	162	24	leg	leg	NN
cord-287670-z6ckhkgg	162	25	paralysis	paralysis	NN
cord-287670-z6ckhkgg	162	26	as	as	RB
cord-287670-z6ckhkgg	162	27	well	well	RB
cord-287670-z6ckhkgg	162	28	as	as	IN
cord-287670-z6ckhkgg	162	29	fast	fast	JJ
cord-287670-z6ckhkgg	162	30	recovery	recovery	NN
cord-287670-z6ckhkgg	162	31	in	in	IN
cord-287670-z6ckhkgg	162	32	global	global	JJ
cord-287670-z6ckhkgg	162	33	Ptx3	Ptx3	NNP
cord-287670-z6ckhkgg	162	34	À	à	NN
cord-287670-z6ckhkgg	162	35	/	/	SYM
cord-287670-z6ckhkgg	162	36	À	à	NN
cord-287670-z6ckhkgg	162	37	mice	mouse	NNS
cord-287670-z6ckhkgg	162	38	compared	compare	VBN
cord-287670-z6ckhkgg	162	39	with	with	IN
cord-287670-z6ckhkgg	162	40	wild	wild	JJ
cord-287670-z6ckhkgg	162	41	-	-	HYPH
cord-287670-z6ckhkgg	162	42	type	type	NN
cord-287670-z6ckhkgg	162	43	controls	control	NNS
cord-287670-z6ckhkgg	162	44	.	.	.
cord-287670-z6ckhkgg	163	1	In	in	IN
cord-287670-z6ckhkgg	163	2	addition	addition	NN
cord-287670-z6ckhkgg	163	3	,	,	,
cord-287670-z6ckhkgg	163	4	reduced	reduced	JJ
cord-287670-z6ckhkgg	163	5	leukocyte	leukocyte	NN
cord-287670-z6ckhkgg	163	6	recruitment	recruitment	NN
cord-287670-z6ckhkgg	163	7	,	,	,
cord-287670-z6ckhkgg	163	8	expression	expression	NN
cord-287670-z6ckhkgg	163	9	of	of	IN
cord-287670-z6ckhkgg	163	10	inflammatory	inflammatory	JJ
cord-287670-z6ckhkgg	163	11	mediators	mediator	NNS
cord-287670-z6ckhkgg	163	12	,	,	,
cord-287670-z6ckhkgg	163	13	and	and	CC
cord-287670-z6ckhkgg	163	14	viral	viral	JJ
cord-287670-z6ckhkgg	163	15	replication	replication	NN
cord-287670-z6ckhkgg	163	16	were	be	VBD
cord-287670-z6ckhkgg	163	17	reported	report	VBN
cord-287670-z6ckhkgg	163	18	with	with	IN
cord-287670-z6ckhkgg	163	19	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	163	20	deficiency	deficiency	NN
cord-287670-z6ckhkgg	163	21	.	.	.
cord-287670-z6ckhkgg	164	1	It	-PRON-	PRP
cord-287670-z6ckhkgg	164	2	was	be	VBD
cord-287670-z6ckhkgg	164	3	proposed	propose	VBN
cord-287670-z6ckhkgg	164	4	that	that	IN
cord-287670-z6ckhkgg	164	5	this	this	DT
cord-287670-z6ckhkgg	164	6	phenotype	phenotype	NN
cord-287670-z6ckhkgg	164	7	could	could	MD
cord-287670-z6ckhkgg	164	8	be	be	VB
cord-287670-z6ckhkgg	164	9	explained	explain	VBN
cord-287670-z6ckhkgg	164	10	by	by	IN
cord-287670-z6ckhkgg	164	11	early	early	JJ
cord-287670-z6ckhkgg	164	12	RRV	RRV	NNP
cord-287670-z6ckhkgg	164	13	and	and	CC
cord-287670-z6ckhkgg	164	14	CHIKV	CHIKV	NNP
cord-287670-z6ckhkgg	164	15	viral	viral	JJ
cord-287670-z6ckhkgg	164	16	entry	entry	NN
cord-287670-z6ckhkgg	164	17	and	and	CC
cord-287670-z6ckhkgg	164	18	replication	replication	NN
cord-287670-z6ckhkgg	164	19	,	,	,
cord-287670-z6ckhkgg	164	20	which	which	WDT
cord-287670-z6ckhkgg	164	21	were	be	VBD
cord-287670-z6ckhkgg	164	22	promoted	promote	VBN
cord-287670-z6ckhkgg	164	23	by	by	IN
cord-287670-z6ckhkgg	164	24	the	the	DT
cord-287670-z6ckhkgg	164	25	binding	binding	NN
cord-287670-z6ckhkgg	164	26	of	of	IN
cord-287670-z6ckhkgg	164	27	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	164	28	to	to	IN
cord-287670-z6ckhkgg	164	29	alphavirus	alphavirus	NNP
cord-287670-z6ckhkgg	164	30	,	,	,
cord-287670-z6ckhkgg	164	31	through	through	IN
cord-287670-z6ckhkgg	164	32	still	still	RB
cord-287670-z6ckhkgg	164	33	undefined	undefined	JJ
cord-287670-z6ckhkgg	164	34	mechanisms	mechanism	NNS
cord-287670-z6ckhkgg	164	35	[	[	-LRB-
cord-287670-z6ckhkgg	164	36	55	55	CD
cord-287670-z6ckhkgg	164	37	]	]	-RRB-
cord-287670-z6ckhkgg	164	38	.	.	.
cord-287670-z6ckhkgg	165	1	Interestingly	interestingly	RB
cord-287670-z6ckhkgg	165	2	,	,	,
cord-287670-z6ckhkgg	165	3	this	this	DT
cord-287670-z6ckhkgg	165	4	suggested	suggest	VBD
cord-287670-z6ckhkgg	165	5	that	that	IN
cord-287670-z6ckhkgg	165	6	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	165	7	might	may	MD
cord-287670-z6ckhkgg	165	8	potentially	potentially	RB
cord-287670-z6ckhkgg	165	9	be	be	VB
cord-287670-z6ckhkgg	165	10	exploited	exploit	VBN
cord-287670-z6ckhkgg	165	11	by	by	IN
cord-287670-z6ckhkgg	165	12	viruses	virus	NNS
cord-287670-z6ckhkgg	165	13	to	to	TO
cord-287670-z6ckhkgg	165	14	facilitate	facilitate	VB
cord-287670-z6ckhkgg	165	15	an	an	DT
cord-287670-z6ckhkgg	165	16	increase	increase	NN
cord-287670-z6ckhkgg	165	17	in	in	IN
cord-287670-z6ckhkgg	165	18	viral	viral	JJ
cord-287670-z6ckhkgg	165	19	entrance	entrance	NN
cord-287670-z6ckhkgg	165	20	and	and	CC
cord-287670-z6ckhkgg	165	21	replication	replication	NN
cord-287670-z6ckhkgg	165	22	in	in	IN
cord-287670-z6ckhkgg	165	23	host	host	NN
cord-287670-z6ckhkgg	165	24	cells	cell	NNS
cord-287670-z6ckhkgg	165	25	[	[	-LRB-
cord-287670-z6ckhkgg	165	26	55	55	CD
cord-287670-z6ckhkgg	165	27	]	]	-RRB-
cord-287670-z6ckhkgg	166	1	(	(	-LRB-
cord-287670-z6ckhkgg	166	2	Figure	figure	NN
cord-287670-z6ckhkgg	166	3	2	2	CD
cord-287670-z6ckhkgg	166	4	)	)	-RRB-
cord-287670-z6ckhkgg	166	5	.	.	.
cord-287670-z6ckhkgg	167	1	In	in	IN
cord-287670-z6ckhkgg	167	2	addition	addition	NN
cord-287670-z6ckhkgg	167	3	to	to	IN
cord-287670-z6ckhkgg	167	4	its	-PRON-	PRP$
cord-287670-z6ckhkgg	167	5	involvement	involvement	NN
cord-287670-z6ckhkgg	167	6	in	in	IN
cord-287670-z6ckhkgg	167	7	immunoregulation	immunoregulation	NN
cord-287670-z6ckhkgg	167	8	,	,	,
cord-287670-z6ckhkgg	167	9	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	167	10	has	have	VBZ
cord-287670-z6ckhkgg	167	11	been	be	VBN
cord-287670-z6ckhkgg	167	12	implicated	implicate	VBN
cord-287670-z6ckhkgg	167	13	in	in	IN
cord-287670-z6ckhkgg	167	14	various	various	JJ
cord-287670-z6ckhkgg	167	15	other	other	JJ
cord-287670-z6ckhkgg	167	16	biological	biological	JJ
cord-287670-z6ckhkgg	167	17	processes	process	NNS
cord-287670-z6ckhkgg	167	18	.	.	.
cord-287670-z6ckhkgg	168	1	For	for	IN
cord-287670-z6ckhkgg	168	2	instance	instance	NN
cord-287670-z6ckhkgg	168	3	,	,	,
cord-287670-z6ckhkgg	168	4	it	-PRON-	PRP
cord-287670-z6ckhkgg	168	5	has	have	VBZ
cord-287670-z6ckhkgg	168	6	been	be	VBN
cord-287670-z6ckhkgg	168	7	postulated	postulate	VBN
cord-287670-z6ckhkgg	168	8	that	that	IN
cord-287670-z6ckhkgg	168	9	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	168	10	also	also	RB
cord-287670-z6ckhkgg	168	11	contributes	contribute	VBZ
cord-287670-z6ckhkgg	168	12	to	to	IN
cord-287670-z6ckhkgg	168	13	tissue	tissue	NN
cord-287670-z6ckhkgg	168	14	remodeling	remodeling	NN
cord-287670-z6ckhkgg	168	15	under	under	IN
cord-287670-z6ckhkgg	168	16	physiological	physiological	JJ
cord-287670-z6ckhkgg	168	17	and	and	CC
cord-287670-z6ckhkgg	168	18	inflammatory	inflammatory	JJ
cord-287670-z6ckhkgg	168	19	conditions	condition	NNS
cord-287670-z6ckhkgg	168	20	(	(	-LRB-
cord-287670-z6ckhkgg	168	21	Figure	figure	NN
cord-287670-z6ckhkgg	168	22	1	1	CD
cord-287670-z6ckhkgg	168	23	)	)	-RRB-
cord-287670-z6ckhkgg	168	24	.	.	.
cord-287670-z6ckhkgg	169	1	The	the	DT
cord-287670-z6ckhkgg	169	2	involvement	involvement	NN
cord-287670-z6ckhkgg	169	3	of	of	IN
cord-287670-z6ckhkgg	169	4	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	169	5	in	in	IN
cord-287670-z6ckhkgg	169	6	physiological	physiological	JJ
cord-287670-z6ckhkgg	169	7	tissue	tissue	NN
cord-287670-z6ckhkgg	169	8	remodeling	remodeling	NN
cord-287670-z6ckhkgg	169	9	was	be	VBD
cord-287670-z6ckhkgg	169	10	first	first	RB
cord-287670-z6ckhkgg	169	11	identified	identify	VBN
cord-287670-z6ckhkgg	169	12	in	in	IN
cord-287670-z6ckhkgg	169	13	PTX3-deficient	PTX3-deficient	NNP
cord-287670-z6ckhkgg	169	14	infertile	infertile	JJ
cord-287670-z6ckhkgg	169	15	female	female	JJ
cord-287670-z6ckhkgg	169	16	mice	mouse	NNS
cord-287670-z6ckhkgg	169	17	[	[	-LRB-
cord-287670-z6ckhkgg	169	18	56	56	CD
cord-287670-z6ckhkgg	169	19	]	]	-RRB-
cord-287670-z6ckhkgg	169	20	.	.	.
cord-287670-z6ckhkgg	170	1	This	this	DT
cord-287670-z6ckhkgg	170	2	phenotype	phenotype	NN
cord-287670-z6ckhkgg	170	3	was	be	VBD
cord-287670-z6ckhkgg	170	4	reported	report	VBN
cord-287670-z6ckhkgg	170	5	to	to	TO
cord-287670-z6ckhkgg	170	6	be	be	VB
cord-287670-z6ckhkgg	170	7	due	due	JJ
cord-287670-z6ckhkgg	170	8	to	to	IN
cord-287670-z6ckhkgg	170	9	defective	defective	JJ
cord-287670-z6ckhkgg	170	10	assembly	assembly	NN
cord-287670-z6ckhkgg	170	11	of	of	IN
cord-287670-z6ckhkgg	170	12	the	the	DT
cord-287670-z6ckhkgg	170	13	hyaluronan	hyaluronan	NNP
cord-287670-z6ckhkgg	170	14	(	(	-LRB-
cord-287670-z6ckhkgg	170	15	HA)-rich	ha)-rich	CD
cord-287670-z6ckhkgg	170	16	matrix	matrix	NN
cord-287670-z6ckhkgg	170	17	that	that	WDT
cord-287670-z6ckhkgg	170	18	forms	form	VBZ
cord-287670-z6ckhkgg	170	19	around	around	IN
cord-287670-z6ckhkgg	170	20	oocytes	oocyte	NNS
cord-287670-z6ckhkgg	170	21	in	in	IN
cord-287670-z6ckhkgg	170	22	preovulatory	preovulatory	JJ
cord-287670-z6ckhkgg	170	23	follicles	follicle	NNS
cord-287670-z6ckhkgg	170	24	,	,	,
cord-287670-z6ckhkgg	170	25	a	a	DT
cord-287670-z6ckhkgg	170	26	process	process	NN
cord-287670-z6ckhkgg	170	27	that	that	WDT
cord-287670-z6ckhkgg	170	28	is	be	VBZ
cord-287670-z6ckhkgg	170	29	absolutely	absolutely	RB
cord-287670-z6ckhkgg	170	30	required	require	VBN
cord-287670-z6ckhkgg	170	31	for	for	IN
cord-287670-z6ckhkgg	170	32	fertilization	fertilization	NN
cord-287670-z6ckhkgg	170	33	in	in	IN
cord-287670-z6ckhkgg	170	34	vivo	vivo	NNP
cord-287670-z6ckhkgg	170	35	[	[	-LRB-
cord-287670-z6ckhkgg	170	36	56	56	CD
cord-287670-z6ckhkgg	170	37	]	]	-RRB-
cord-287670-z6ckhkgg	170	38	.	.	.
cord-287670-z6ckhkgg	171	1	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	171	2	produced	produce	VBN
cord-287670-z6ckhkgg	171	3	by	by	IN
cord-287670-z6ckhkgg	171	4	cumulus	cumulus	NN
cord-287670-z6ckhkgg	171	5	cells	cell	NNS
cord-287670-z6ckhkgg	171	6	during	during	IN
cord-287670-z6ckhkgg	171	7	the	the	DT
cord-287670-z6ckhkgg	171	8	preovulatory	preovulatory	JJ
cord-287670-z6ckhkgg	171	9	phase	phase	NN
cord-287670-z6ckhkgg	171	10	was	be	VBD
cord-287670-z6ckhkgg	171	11	found	find	VBN
cord-287670-z6ckhkgg	171	12	to	to	TO
cord-287670-z6ckhkgg	171	13	interact	interact	VB
cord-287670-z6ckhkgg	171	14	through	through	IN
cord-287670-z6ckhkgg	171	15	its	-PRON-	PRP$
cord-287670-z6ckhkgg	171	16	N	n	CD
cord-287670-z6ckhkgg	171	17	-	-	HYPH
cord-287670-z6ckhkgg	171	18	terminal	terminal	NN
cord-287670-z6ckhkgg	171	19	domain	domain	NN
cord-287670-z6ckhkgg	171	20	with	with	IN
cord-287670-z6ckhkgg	171	21	two	two	CD
cord-287670-z6ckhkgg	171	22	HA	HA	NNP
cord-287670-z6ckhkgg	171	23	-	-	HYPH
cord-287670-z6ckhkgg	171	24	binding	bind	VBG
cord-287670-z6ckhkgg	171	25	proteins	protein	NNS
cord-287670-z6ckhkgg	171	26	,	,	,
cord-287670-z6ckhkgg	171	27	TNF/-induced	tnf/-induce	VBD
cord-287670-z6ckhkgg	171	28	protein	protein	NN
cord-287670-z6ckhkgg	171	29	6	6	CD
cord-287670-z6ckhkgg	171	30	(	(	-LRB-
cord-287670-z6ckhkgg	171	31	TNFAIP6	tnfaip6	NN
cord-287670-z6ckhkgg	171	32	or	or	CC
cord-287670-z6ckhkgg	171	33	TSG-6	TSG-6	NNP
cord-287670-z6ckhkgg	171	34	)	)	-RRB-
cord-287670-z6ckhkgg	171	35	and	and	CC
cord-287670-z6ckhkgg	171	36	the	the	DT
cord-287670-z6ckhkgg	171	37	serum	serum	NN
cord-287670-z6ckhkgg	171	38	proteoglycan	proteoglycan	NN
cord-287670-z6ckhkgg	171	39	inter-/-trypsin	inter-/-trypsin	CD
cord-287670-z6ckhkgg	171	40	inhibitor	inhibitor	NN
cord-287670-z6ckhkgg	172	1	(	(	-LRB-
cord-287670-z6ckhkgg	172	2	I	i	NN
cord-287670-z6ckhkgg	172	3	/	/	,
cord-287670-z6ckhkgg	172	4	I	i	NN
cord-287670-z6ckhkgg	172	5	)	)	-RRB-
cord-287670-z6ckhkgg	172	6	,	,	,
cord-287670-z6ckhkgg	172	7	which	which	WDT
cord-287670-z6ckhkgg	172	8	are	be	VBP
cord-287670-z6ckhkgg	172	9	major	major	JJ
cord-287670-z6ckhkgg	172	10	functional	functional	JJ
cord-287670-z6ckhkgg	172	11	proteins	protein	NNS
cord-287670-z6ckhkgg	172	12	of	of	IN
cord-287670-z6ckhkgg	172	13	the	the	DT
cord-287670-z6ckhkgg	172	14	cumulus	cumulus	NN
cord-287670-z6ckhkgg	172	15	ECM	ECM	NNP
cord-287670-z6ckhkgg	172	16	,	,	,
cord-287670-z6ckhkgg	172	17	thus	thus	RB
cord-287670-z6ckhkgg	172	18	providing	provide	VBG
cord-287670-z6ckhkgg	172	19	structural	structural	JJ
cord-287670-z6ckhkgg	172	20	integrity	integrity	NN
cord-287670-z6ckhkgg	172	21	to	to	IN
cord-287670-z6ckhkgg	172	22	the	the	DT
cord-287670-z6ckhkgg	172	23	cumulus	cumulus	NN
cord-287670-z6ckhkgg	172	24	matrix	matrix	NN
cord-287670-z6ckhkgg	172	25	[	[	-LRB-
cord-287670-z6ckhkgg	172	26	56	56	CD
cord-287670-z6ckhkgg	172	27	,	,	,
cord-287670-z6ckhkgg	172	28	57	57	CD
cord-287670-z6ckhkgg	172	29	]	]	-RRB-
cord-287670-z6ckhkgg	172	30	.	.	.
cord-287670-z6ckhkgg	173	1	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	173	2	is	be	VBZ
cord-287670-z6ckhkgg	173	3	thus	thus	RB
cord-287670-z6ckhkgg	173	4	required	require	VBN
cord-287670-z6ckhkgg	173	5	to	to	TO
cord-287670-z6ckhkgg	173	6	facilitate	facilitate	VB
cord-287670-z6ckhkgg	173	7	murine	murine	JJ
cord-287670-z6ckhkgg	173	8	female	female	JJ
cord-287670-z6ckhkgg	173	9	fertility	fertility	NN
cord-287670-z6ckhkgg	173	10	.	.	.
cord-287670-z6ckhkgg	174	1	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	174	2	has	have	VBZ
cord-287670-z6ckhkgg	174	3	also	also	RB
cord-287670-z6ckhkgg	174	4	been	be	VBN
cord-287670-z6ckhkgg	174	5	found	find	VBN
cord-287670-z6ckhkgg	174	6	to	to	TO
cord-287670-z6ckhkgg	174	7	bind	bind	VB
cord-287670-z6ckhkgg	174	8	various	various	JJ
cord-287670-z6ckhkgg	174	9	fibroblast	fibroblast	NN
cord-287670-z6ckhkgg	174	10	growth	growth	NN
cord-287670-z6ckhkgg	174	11	factors	factor	NNS
cord-287670-z6ckhkgg	174	12	(	(	-LRB-
cord-287670-z6ckhkgg	174	13	FGFs	fgf	NNS
cord-287670-z6ckhkgg	174	14	)	)	-RRB-
cord-287670-z6ckhkgg	174	15	via	via	IN
cord-287670-z6ckhkgg	174	16	its	-PRON-	PRP$
cord-287670-z6ckhkgg	174	17	N	n	CD
cord-287670-z6ckhkgg	174	18	-	-	HYPH
cord-287670-z6ckhkgg	174	19	terminal	terminal	NN
cord-287670-z6ckhkgg	174	20	extension	extension	NN
cord-287670-z6ckhkgg	174	21	,	,	,
cord-287670-z6ckhkgg	174	22	including	include	VBG
cord-287670-z6ckhkgg	174	23	FGF2	FGF2	NNP
cord-287670-z6ckhkgg	174	24	,	,	,
cord-287670-z6ckhkgg	174	25	FGF6	FGF6	NNP
cord-287670-z6ckhkgg	174	26	,	,	,
cord-287670-z6ckhkgg	174	27	FGF8b	FGF8b	NNP
cord-287670-z6ckhkgg	174	28	,	,	,
cord-287670-z6ckhkgg	174	29	FGF10	fgf10	JJ
cord-287670-z6ckhkgg	174	30	,	,	,
cord-287670-z6ckhkgg	174	31	and	and	CC
cord-287670-z6ckhkgg	174	32	FGF17	FGF17	NNP
cord-287670-z6ckhkgg	174	33	[	[	-LRB-
cord-287670-z6ckhkgg	174	34	58	58	CD
cord-287670-z6ckhkgg	174	35	]	]	-RRB-
cord-287670-z6ckhkgg	174	36	[	[	-LRB-
cord-287670-z6ckhkgg	174	37	59	59	CD
cord-287670-z6ckhkgg	174	38	]	]	-RRB-
cord-287670-z6ckhkgg	174	39	[	[	-LRB-
cord-287670-z6ckhkgg	174	40	60	60	CD
cord-287670-z6ckhkgg	174	41	]	]	-RRB-
cord-287670-z6ckhkgg	174	42	,	,	,
cord-287670-z6ckhkgg	174	43	inhibiting	inhibit	VBG
cord-287670-z6ckhkgg	174	44	FGF	FGF	NNP
cord-287670-z6ckhkgg	174	45	-	-	HYPH
cord-287670-z6ckhkgg	174	46	dependent	dependent	JJ
cord-287670-z6ckhkgg	174	47	EC	EC	NNP
cord-287670-z6ckhkgg	174	48	proliferation	proliferation	NN
cord-287670-z6ckhkgg	174	49	in	in	IN
cord-287670-z6ckhkgg	174	50	vitro	vitro	FW
cord-287670-z6ckhkgg	174	51	and	and	CC
cord-287670-z6ckhkgg	174	52	angiogenesis	angiogenesis	NN
cord-287670-z6ckhkgg	174	53	in	in	IN
cord-287670-z6ckhkgg	174	54	vivo	vivo	NN
cord-287670-z6ckhkgg	174	55	in	in	IN
cord-287670-z6ckhkgg	174	56	an	an	DT
cord-287670-z6ckhkgg	174	57	animal	animal	NN
cord-287670-z6ckhkgg	174	58	model	model	NN
cord-287670-z6ckhkgg	174	59	using	use	VBG
cord-287670-z6ckhkgg	174	60	chick	chick	NNP
cord-287670-z6ckhkgg	174	61	embryo	embryo	NNP
cord-287670-z6ckhkgg	174	62	chorioallantoic	chorioallantoic	NNP
cord-287670-z6ckhkgg	174	63	membranes	membrane	NNS
cord-287670-z6ckhkgg	174	64	[	[	-LRB-
cord-287670-z6ckhkgg	174	65	61	61	CD
cord-287670-z6ckhkgg	174	66	]	]	-RRB-
cord-287670-z6ckhkgg	174	67	.	.	.
cord-287670-z6ckhkgg	175	1	In	in	IN
cord-287670-z6ckhkgg	175	2	addition	addition	NN
cord-287670-z6ckhkgg	175	3	,	,	,
cord-287670-z6ckhkgg	175	4	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	175	5	has	have	VBZ
cord-287670-z6ckhkgg	175	6	been	be	VBN
cord-287670-z6ckhkgg	175	7	demonstrated	demonstrate	VBN
cord-287670-z6ckhkgg	175	8	to	to	TO
cord-287670-z6ckhkgg	175	9	inhibit	inhibit	VB
cord-287670-z6ckhkgg	175	10	FGF2dependent	fgf2dependent	CD
cord-287670-z6ckhkgg	175	11	smooth	smooth	JJ
cord-287670-z6ckhkgg	175	12	muscle	muscle	NN
cord-287670-z6ckhkgg	175	13	cell	cell	NN
cord-287670-z6ckhkgg	175	14	(	(	-LRB-
cord-287670-z6ckhkgg	175	15	SMC	SMC	NNP
cord-287670-z6ckhkgg	175	16	)	)	-RRB-
cord-287670-z6ckhkgg	175	17	proliferation	proliferation	NN
cord-287670-z6ckhkgg	175	18	and	and	CC
cord-287670-z6ckhkgg	175	19	suppressed	suppress	VBD
cord-287670-z6ckhkgg	175	20	the	the	DT
cord-287670-z6ckhkgg	175	21	mitogenic	mitogenic	NNP
cord-287670-z6ckhkgg	175	22	and	and	CC
cord-287670-z6ckhkgg	175	23	chemotactic	chemotactic	JJ
cord-287670-z6ckhkgg	175	24	activity	activity	NN
cord-287670-z6ckhkgg	175	25	exerted	exert	VBN
cord-287670-z6ckhkgg	175	26	by	by	IN
cord-287670-z6ckhkgg	175	27	FGF2	FGF2	NNP
cord-287670-z6ckhkgg	175	28	on	on	IN
cord-287670-z6ckhkgg	175	29	these	these	DT
cord-287670-z6ckhkgg	175	30	cells	cell	NNS
cord-287670-z6ckhkgg	175	31	[	[	-LRB-
cord-287670-z6ckhkgg	175	32	62	62	CD
cord-287670-z6ckhkgg	175	33	]	]	-RRB-
cord-287670-z6ckhkgg	175	34	.	.	.
cord-287670-z6ckhkgg	176	1	It	-PRON-	PRP
cord-287670-z6ckhkgg	176	2	has	have	VBZ
cord-287670-z6ckhkgg	176	3	been	be	VBN
cord-287670-z6ckhkgg	176	4	therefore	therefore	RB
cord-287670-z6ckhkgg	176	5	suggested	suggest	VBN
cord-287670-z6ckhkgg	176	6	that	that	IN
cord-287670-z6ckhkgg	176	7	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	176	8	produced	produce	VBN
cord-287670-z6ckhkgg	176	9	by	by	IN
cord-287670-z6ckhkgg	176	10	ECs	ec	NNS
cord-287670-z6ckhkgg	176	11	and	and	CC
cord-287670-z6ckhkgg	176	12	inflammatory	inflammatory	JJ
cord-287670-z6ckhkgg	176	13	cells	cell	NNS
cord-287670-z6ckhkgg	176	14	,	,	,
cord-287670-z6ckhkgg	176	15	which	which	WDT
cord-287670-z6ckhkgg	176	16	are	be	VBP
cord-287670-z6ckhkgg	176	17	a	a	DT
cord-287670-z6ckhkgg	176	18	major	major	JJ
cord-287670-z6ckhkgg	176	19	source	source	NN
cord-287670-z6ckhkgg	176	20	of	of	IN
cord-287670-z6ckhkgg	176	21	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	176	22	,	,	,
cord-287670-z6ckhkgg	176	23	may	may	MD
cord-287670-z6ckhkgg	176	24	affect	affect	VB
cord-287670-z6ckhkgg	176	25	the	the	DT
cord-287670-z6ckhkgg	176	26	autocrine	autocrine	NN
cord-287670-z6ckhkgg	176	27	and	and	CC
cord-287670-z6ckhkgg	176	28	paracrine	paracrine	JJ
cord-287670-z6ckhkgg	176	29	activity	activity	NN
cord-287670-z6ckhkgg	176	30	of	of	IN
cord-287670-z6ckhkgg	176	31	FGFs	fgf	NNS
cord-287670-z6ckhkgg	176	32	on	on	IN
cord-287670-z6ckhkgg	176	33	endothelium	endothelium	NN
cord-287670-z6ckhkgg	176	34	and	and	CC
cord-287670-z6ckhkgg	176	35	SMCs	smc	NNS
cord-287670-z6ckhkgg	176	36	,	,	,
cord-287670-z6ckhkgg	176	37	providing	provide	VBG
cord-287670-z6ckhkgg	176	38	,	,	,
cord-287670-z6ckhkgg	176	39	in	in	IN
cord-287670-z6ckhkgg	176	40	turn	turn	NN
cord-287670-z6ckhkgg	176	41	,	,	,
cord-287670-z6ckhkgg	176	42	a	a	DT
cord-287670-z6ckhkgg	176	43	mechanism	mechanism	NN
cord-287670-z6ckhkgg	176	44	for	for	IN
cord-287670-z6ckhkgg	176	45	finely	finely	RB
cord-287670-z6ckhkgg	176	46	tuning	tune	VBG
cord-287670-z6ckhkgg	176	47	the	the	DT
cord-287670-z6ckhkgg	176	48	neovascularization	neovascularization	NN
cord-287670-z6ckhkgg	176	49	processes	process	NNS
cord-287670-z6ckhkgg	176	50	and	and	CC
cord-287670-z6ckhkgg	176	51	restenosis	restenosis	NN
cord-287670-z6ckhkgg	176	52	of	of	IN
cord-287670-z6ckhkgg	176	53	carotid	carotid	JJ
cord-287670-z6ckhkgg	176	54	arteries	artery	NNS
cord-287670-z6ckhkgg	176	55	in	in	IN
cord-287670-z6ckhkgg	176	56	rodent	rodent	NN
cord-287670-z6ckhkgg	176	57	models	model	NNS
cord-287670-z6ckhkgg	176	58	of	of	IN
cord-287670-z6ckhkgg	176	59	arterial	arterial	JJ
cord-287670-z6ckhkgg	176	60	balloon	balloon	NN
cord-287670-z6ckhkgg	176	61	injury	injury	NN
cord-287670-z6ckhkgg	176	62	[	[	-LRB-
cord-287670-z6ckhkgg	176	63	63	63	CD
cord-287670-z6ckhkgg	176	64	,	,	,
cord-287670-z6ckhkgg	176	65	64	64	CD
cord-287670-z6ckhkgg	176	66	]	]	-RRB-
cord-287670-z6ckhkgg	176	67	.	.	.
cord-287670-z6ckhkgg	177	1	Additional	additional	JJ
cord-287670-z6ckhkgg	177	2	evidence	evidence	NN
cord-287670-z6ckhkgg	177	3	has	have	VBZ
cord-287670-z6ckhkgg	177	4	indicated	indicate	VBN
cord-287670-z6ckhkgg	177	5	that	that	IN
cord-287670-z6ckhkgg	177	6	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	177	7	is	be	VBZ
cord-287670-z6ckhkgg	177	8	involved	involve	VBN
cord-287670-z6ckhkgg	177	9	in	in	IN
cord-287670-z6ckhkgg	177	10	modulating	modulate	VBG
cord-287670-z6ckhkgg	177	11	inflammation	inflammation	NN
cord-287670-z6ckhkgg	177	12	and	and	CC
cord-287670-z6ckhkgg	177	13	tissue	tissue	NN
cord-287670-z6ckhkgg	177	14	damage	damage	NN
cord-287670-z6ckhkgg	177	15	in	in	IN
cord-287670-z6ckhkgg	177	16	animal	animal	NN
cord-287670-z6ckhkgg	177	17	models	model	NNS
cord-287670-z6ckhkgg	177	18	of	of	IN
cord-287670-z6ckhkgg	177	19	sterile	sterile	JJ
cord-287670-z6ckhkgg	177	20	injury	injury	NN
cord-287670-z6ckhkgg	177	21	[	[	-LRB-
cord-287670-z6ckhkgg	177	22	22	22	CD
cord-287670-z6ckhkgg	177	23	,	,	,
cord-287670-z6ckhkgg	177	24	65	65	CD
cord-287670-z6ckhkgg	177	25	]	]	-RRB-
cord-287670-z6ckhkgg	177	26	.	.	.
cord-287670-z6ckhkgg	178	1	For	for	IN
cord-287670-z6ckhkgg	178	2	example	example	NN
cord-287670-z6ckhkgg	178	3	,	,	,
cord-287670-z6ckhkgg	178	4	in	in	IN
cord-287670-z6ckhkgg	178	5	a	a	DT
cord-287670-z6ckhkgg	178	6	murine	murine	JJ
cord-287670-z6ckhkgg	178	7	model	model	NN
cord-287670-z6ckhkgg	178	8	of	of	IN
cord-287670-z6ckhkgg	178	9	cardiac	cardiac	JJ
cord-287670-z6ckhkgg	178	10	ischemia	ischemia	NN
cord-287670-z6ckhkgg	178	11	/	/	SYM
cord-287670-z6ckhkgg	178	12	reperfusion	reperfusion	NN
cord-287670-z6ckhkgg	178	13	injury	injury	NN
cord-287670-z6ckhkgg	178	14	,	,	,
cord-287670-z6ckhkgg	178	15	global	global	JJ
cord-287670-z6ckhkgg	178	16	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	178	17	deficiency	deficiency	NN
cord-287670-z6ckhkgg	178	18	was	be	VBD
cord-287670-z6ckhkgg	178	19	associated	associate	VBN
cord-287670-z6ckhkgg	178	20	with	with	IN
cord-287670-z6ckhkgg	178	21	increased	increase	VBN
cord-287670-z6ckhkgg	178	22	tissue	tissue	NN
cord-287670-z6ckhkgg	178	23	damage	damage	NN
cord-287670-z6ckhkgg	178	24	and	and	CC
cord-287670-z6ckhkgg	178	25	neutrophil	neutrophil	NN
cord-287670-z6ckhkgg	178	26	infiltration	infiltration	NN
cord-287670-z6ckhkgg	178	27	in	in	IN
cord-287670-z6ckhkgg	178	28	the	the	DT
cord-287670-z6ckhkgg	178	29	myocardium	myocardium	NN
cord-287670-z6ckhkgg	178	30	[	[	-LRB-
cord-287670-z6ckhkgg	178	31	22	22	CD
cord-287670-z6ckhkgg	178	32	]	]	-RRB-
cord-287670-z6ckhkgg	178	33	.	.	.
cord-287670-z6ckhkgg	179	1	Since	since	IN
cord-287670-z6ckhkgg	179	2	higher	high	JJR
cord-287670-z6ckhkgg	179	3	deposition	deposition	NN
cord-287670-z6ckhkgg	179	4	of	of	IN
cord-287670-z6ckhkgg	179	5	complement	complement	NN
cord-287670-z6ckhkgg	179	6	C3	C3	NNP
cord-287670-z6ckhkgg	179	7	was	be	VBD
cord-287670-z6ckhkgg	179	8	observed	observe	VBN
cord-287670-z6ckhkgg	179	9	in	in	IN
cord-287670-z6ckhkgg	179	10	the	the	DT
cord-287670-z6ckhkgg	179	11	infarct	infarct	NN
cord-287670-z6ckhkgg	179	12	area	area	NN
cord-287670-z6ckhkgg	179	13	of	of	IN
cord-287670-z6ckhkgg	179	14	PTX3-deficient	PTX3-deficient	NNP
cord-287670-z6ckhkgg	179	15	mice	mouse	NNS
cord-287670-z6ckhkgg	179	16	relative	relative	JJ
cord-287670-z6ckhkgg	179	17	to	to	IN
cord-287670-z6ckhkgg	179	18	controls	control	NNS
cord-287670-z6ckhkgg	179	19	[	[	-LRB-
cord-287670-z6ckhkgg	179	20	22	22	CD
cord-287670-z6ckhkgg	179	21	]	]	-RRB-
cord-287670-z6ckhkgg	179	22	,	,	,
cord-287670-z6ckhkgg	179	23	it	-PRON-	PRP
cord-287670-z6ckhkgg	179	24	was	be	VBD
cord-287670-z6ckhkgg	179	25	hypothesized	hypothesize	VBN
cord-287670-z6ckhkgg	179	26	that	that	IN
cord-287670-z6ckhkgg	179	27	this	this	DT
cord-287670-z6ckhkgg	179	28	phenotype	phenotype	NN
cord-287670-z6ckhkgg	179	29	could	could	MD
cord-287670-z6ckhkgg	179	30	be	be	VB
cord-287670-z6ckhkgg	179	31	attributed	attribute	VBN
cord-287670-z6ckhkgg	179	32	to	to	IN
cord-287670-z6ckhkgg	179	33	the	the	DT
cord-287670-z6ckhkgg	179	34	potential	potential	JJ
cord-287670-z6ckhkgg	179	35	defective	defective	JJ
cord-287670-z6ckhkgg	179	36	regulation	regulation	NN
cord-287670-z6ckhkgg	179	37	of	of	IN
cord-287670-z6ckhkgg	179	38	complement	complement	JJ
cord-287670-z6ckhkgg	179	39	activation	activation	NN
cord-287670-z6ckhkgg	179	40	via	via	IN
cord-287670-z6ckhkgg	179	41	Factor	factor	NN
cord-287670-z6ckhkgg	179	42	H	H	NNP
cord-287670-z6ckhkgg	179	43	[	[	-LRB-
cord-287670-z6ckhkgg	179	44	27	27	CD
cord-287670-z6ckhkgg	179	45	]	]	-RRB-
cord-287670-z6ckhkgg	179	46	.	.	.
cord-287670-z6ckhkgg	180	1	Surface	surface	NN
cord-287670-z6ckhkgg	180	2	-	-	HYPH
cord-287670-z6ckhkgg	180	3	bound	bind	VBN
cord-287670-z6ckhkgg	180	4	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	180	5	was	be	VBD
cord-287670-z6ckhkgg	180	6	found	find	VBN
cord-287670-z6ckhkgg	180	7	to	to	TO
cord-287670-z6ckhkgg	180	8	enhance	enhance	VB
cord-287670-z6ckhkgg	180	9	the	the	DT
cord-287670-z6ckhkgg	180	10	recruitment	recruitment	NN
cord-287670-z6ckhkgg	180	11	of	of	IN
cord-287670-z6ckhkgg	180	12	Factor	Factor	NNP
cord-287670-z6ckhkgg	180	13	H	H	NNP
cord-287670-z6ckhkgg	180	14	,	,	,
cord-287670-z6ckhkgg	180	15	which	which	WDT
cord-287670-z6ckhkgg	180	16	retained	retain	VBD
cord-287670-z6ckhkgg	180	17	its	-PRON-	PRP$
cord-287670-z6ckhkgg	180	18	cofactor	cofactor	NN
cord-287670-z6ckhkgg	180	19	activity	activity	NN
cord-287670-z6ckhkgg	180	20	leading	lead	VBG
cord-287670-z6ckhkgg	180	21	to	to	IN
cord-287670-z6ckhkgg	180	22	C3b	c3b	NN
cord-287670-z6ckhkgg	180	23	cleavage	cleavage	NN
cord-287670-z6ckhkgg	180	24	[	[	-LRB-
cord-287670-z6ckhkgg	180	25	27	27	CD
cord-287670-z6ckhkgg	180	26	]	]	-RRB-
cord-287670-z6ckhkgg	180	27	.	.	.
cord-287670-z6ckhkgg	181	1	This	this	DT
cord-287670-z6ckhkgg	181	2	indicated	indicate	VBD
cord-287670-z6ckhkgg	181	3	that	that	IN
cord-287670-z6ckhkgg	181	4	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	181	5	participates	participate	VBZ
cord-287670-z6ckhkgg	181	6	in	in	IN
cord-287670-z6ckhkgg	181	7	the	the	DT
cord-287670-z6ckhkgg	181	8	localization	localization	NN
cord-287670-z6ckhkgg	181	9	of	of	IN
cord-287670-z6ckhkgg	181	10	functionally	functionally	RB
cord-287670-z6ckhkgg	181	11	active	active	JJ
cord-287670-z6ckhkgg	181	12	Factor	factor	NN
cord-287670-z6ckhkgg	181	13	H	h	NN
cord-287670-z6ckhkgg	181	14	in	in	IN
cord-287670-z6ckhkgg	181	15	sites	site	NNS
cord-287670-z6ckhkgg	181	16	of	of	IN
cord-287670-z6ckhkgg	181	17	tissue	tissue	NN
cord-287670-z6ckhkgg	181	18	damage	damage	NN
cord-287670-z6ckhkgg	181	19	[	[	-LRB-
cord-287670-z6ckhkgg	181	20	27	27	CD
cord-287670-z6ckhkgg	181	21	]	]	-RRB-
cord-287670-z6ckhkgg	181	22	.	.	.
cord-287670-z6ckhkgg	182	1	Moreover	moreover	RB
cord-287670-z6ckhkgg	182	2	,	,	,
cord-287670-z6ckhkgg	182	3	PTX3-deficiency	PTX3-deficiency	NNP
cord-287670-z6ckhkgg	182	4	in	in	IN
cord-287670-z6ckhkgg	182	5	apolipoprotein	apolipoprotein	NN
cord-287670-z6ckhkgg	182	6	E	e	NN
cord-287670-z6ckhkgg	182	7	knockout	knockout	NN
cord-287670-z6ckhkgg	182	8	mice	mouse	NNS
cord-287670-z6ckhkgg	183	1	(	(	-LRB-
cord-287670-z6ckhkgg	183	2	ApoE	ApoE	NNS
cord-287670-z6ckhkgg	183	3	mice	mouse	NNS
cord-287670-z6ckhkgg	183	4	)	)	-RRB-
cord-287670-z6ckhkgg	183	5	was	be	VBD
cord-287670-z6ckhkgg	183	6	associated	associate	VBN
cord-287670-z6ckhkgg	183	7	with	with	IN
cord-287670-z6ckhkgg	183	8	increased	increase	VBN
cord-287670-z6ckhkgg	183	9	atherosclerosis	atherosclerosis	NN
cord-287670-z6ckhkgg	183	10	and	and	CC
cord-287670-z6ckhkgg	183	11	macrophage	macrophage	NN
cord-287670-z6ckhkgg	183	12	accumulation	accumulation	NN
cord-287670-z6ckhkgg	183	13	within	within	IN
cord-287670-z6ckhkgg	183	14	atherosclerotic	atherosclerotic	JJ
cord-287670-z6ckhkgg	183	15	plaques	plaque	NNS
cord-287670-z6ckhkgg	183	16	as	as	RB
cord-287670-z6ckhkgg	183	17	well	well	RB
cord-287670-z6ckhkgg	183	18	as	as	IN
cord-287670-z6ckhkgg	183	19	with	with	IN
cord-287670-z6ckhkgg	183	20	more	more	RBR
cord-287670-z6ckhkgg	183	21	pronounced	pronounce	VBN
cord-287670-z6ckhkgg	183	22	inflammatory	inflammatory	JJ
cord-287670-z6ckhkgg	183	23	profiles	profile	NNS
cord-287670-z6ckhkgg	183	24	in	in	IN
cord-287670-z6ckhkgg	183	25	vascular	vascular	JJ
cord-287670-z6ckhkgg	183	26	walls	wall	NNS
cord-287670-z6ckhkgg	183	27	,	,	,
cord-287670-z6ckhkgg	183	28	as	as	IN
cord-287670-z6ckhkgg	183	29	revealed	reveal	VBN
cord-287670-z6ckhkgg	183	30	by	by	IN
cord-287670-z6ckhkgg	183	31	the	the	DT
cord-287670-z6ckhkgg	183	32	increased	increase	VBN
cord-287670-z6ckhkgg	183	33	expression	expression	NN
cord-287670-z6ckhkgg	183	34	of	of	IN
cord-287670-z6ckhkgg	183	35	inflammatory	inflammatory	JJ
cord-287670-z6ckhkgg	183	36	mediators	mediator	NNS
cord-287670-z6ckhkgg	183	37	and	and	CC
cord-287670-z6ckhkgg	183	38	macrophage	macrophage	NN
cord-287670-z6ckhkgg	183	39	recruitment	recruitment	NN
cord-287670-z6ckhkgg	183	40	within	within	IN
cord-287670-z6ckhkgg	183	41	plaques	plaque	NNS
cord-287670-z6ckhkgg	183	42	[	[	-LRB-
cord-287670-z6ckhkgg	183	43	65	65	CD
cord-287670-z6ckhkgg	183	44	]	]	-RRB-
cord-287670-z6ckhkgg	183	45	.	.	.
cord-287670-z6ckhkgg	184	1	In	in	IN
cord-287670-z6ckhkgg	184	2	addition	addition	NN
cord-287670-z6ckhkgg	184	3	to	to	IN
cord-287670-z6ckhkgg	184	4	regulating	regulating	NN
cord-287670-z6ckhkgg	184	5	complement	complement	NN
cord-287670-z6ckhkgg	184	6	,	,	,
cord-287670-z6ckhkgg	184	7	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	184	8	has	have	VBZ
cord-287670-z6ckhkgg	184	9	been	be	VBN
cord-287670-z6ckhkgg	184	10	reported	report	VBN
cord-287670-z6ckhkgg	184	11	to	to	TO
cord-287670-z6ckhkgg	184	12	selectively	selectively	RB
cord-287670-z6ckhkgg	184	13	bind	bind	VB
cord-287670-z6ckhkgg	184	14	P	p	NN
cord-287670-z6ckhkgg	184	15	-	-	HYPH
cord-287670-z6ckhkgg	184	16	selectin	selectin	NNP
cord-287670-z6ckhkgg	184	17	via	via	IN
cord-287670-z6ckhkgg	184	18	its	-PRON-	PRP$
cord-287670-z6ckhkgg	184	19	N	n	CD
cord-287670-z6ckhkgg	184	20	-	-	HYPH
cord-287670-z6ckhkgg	184	21	linked	link	VBN
cord-287670-z6ckhkgg	184	22	glycosidic	glycosidic	NN
cord-287670-z6ckhkgg	184	23	moiety	moiety	NN
cord-287670-z6ckhkgg	184	24	,	,	,
cord-287670-z6ckhkgg	184	25	thus	thus	RB
cord-287670-z6ckhkgg	184	26	inhibiting	inhibit	VBG
cord-287670-z6ckhkgg	184	27	leukocyte	leukocyte	NN
cord-287670-z6ckhkgg	184	28	rolling	roll	VBG
cord-287670-z6ckhkgg	184	29	on	on	IN
cord-287670-z6ckhkgg	184	30	endothelium	endothelium	NN
cord-287670-z6ckhkgg	184	31	and	and	CC
cord-287670-z6ckhkgg	184	32	providing	provide	VBG
cord-287670-z6ckhkgg	184	33	a	a	DT
cord-287670-z6ckhkgg	184	34	negative	negative	JJ
cord-287670-z6ckhkgg	184	35	feedback	feedback	NN
cord-287670-z6ckhkgg	184	36	loop	loop	NN
cord-287670-z6ckhkgg	184	37	that	that	WDT
cord-287670-z6ckhkgg	184	38	prevents	prevent	VBZ
cord-287670-z6ckhkgg	184	39	excessive	excessive	JJ
cord-287670-z6ckhkgg	184	40	P	p	NN
cord-287670-z6ckhkgg	184	41	-	-	HYPH
cord-287670-z6ckhkgg	184	42	selectin	selectin	JJ
cord-287670-z6ckhkgg	184	43	-	-	HYPH
cord-287670-z6ckhkgg	184	44	dependent	dependent	JJ
cord-287670-z6ckhkgg	184	45	recruitment	recruitment	NN
cord-287670-z6ckhkgg	184	46	of	of	IN
cord-287670-z6ckhkgg	184	47	neutrophils	neutrophil	NNS
cord-287670-z6ckhkgg	184	48	and	and	CC
cord-287670-z6ckhkgg	184	49	tissue	tissue	NN
cord-287670-z6ckhkgg	184	50	damage	damage	NN
cord-287670-z6ckhkgg	184	51	in	in	IN
cord-287670-z6ckhkgg	184	52	murine	murine	JJ
cord-287670-z6ckhkgg	184	53	models	model	NNS
cord-287670-z6ckhkgg	184	54	of	of	IN
cord-287670-z6ckhkgg	184	55	acute	acute	JJ
cord-287670-z6ckhkgg	184	56	lung	lung	NN
cord-287670-z6ckhkgg	184	57	injury	injury	NN
cord-287670-z6ckhkgg	184	58	,	,	,
cord-287670-z6ckhkgg	184	59	pleurisy	pleurisy	NN
cord-287670-z6ckhkgg	184	60	,	,	,
cord-287670-z6ckhkgg	184	61	and	and	CC
cord-287670-z6ckhkgg	184	62	mesenteric	mesenteric	JJ
cord-287670-z6ckhkgg	184	63	inflammation	inflammation	NN
cord-287670-z6ckhkgg	184	64	[	[	-LRB-
cord-287670-z6ckhkgg	184	65	30	30	CD
cord-287670-z6ckhkgg	184	66	]	]	-RRB-
cord-287670-z6ckhkgg	184	67	as	as	RB
cord-287670-z6ckhkgg	184	68	well	well	RB
cord-287670-z6ckhkgg	184	69	as	as	IN
cord-287670-z6ckhkgg	184	70	in	in	IN
cord-287670-z6ckhkgg	184	71	post	post	JJ
cord-287670-z6ckhkgg	184	72	-	-	JJ
cord-287670-z6ckhkgg	184	73	ischemic	ischemic	JJ
cord-287670-z6ckhkgg	184	74	acute	acute	JJ
cord-287670-z6ckhkgg	184	75	kidney	kidney	NN
cord-287670-z6ckhkgg	184	76	injury	injury	NN
cord-287670-z6ckhkgg	184	77	[	[	-LRB-
cord-287670-z6ckhkgg	184	78	66	66	CD
cord-287670-z6ckhkgg	184	79	]	]	-RRB-
cord-287670-z6ckhkgg	184	80	.	.	.
cord-287670-z6ckhkgg	185	1	Recently	recently	RB
cord-287670-z6ckhkgg	185	2	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	185	3	was	be	VBD
cord-287670-z6ckhkgg	185	4	demonstrated	demonstrate	VBN
cord-287670-z6ckhkgg	185	5	to	to	TO
cord-287670-z6ckhkgg	185	6	play	play	VB
cord-287670-z6ckhkgg	185	7	a	a	DT
cord-287670-z6ckhkgg	185	8	nonredundant	nonredundant	JJ
cord-287670-z6ckhkgg	185	9	role	role	NN
cord-287670-z6ckhkgg	185	10	in	in	IN
cord-287670-z6ckhkgg	185	11	tissue	tissue	NN
cord-287670-z6ckhkgg	185	12	repair	repair	NN
cord-287670-z6ckhkgg	185	13	,	,	,
cord-287670-z6ckhkgg	185	14	through	through	IN
cord-287670-z6ckhkgg	185	15	a	a	DT
cord-287670-z6ckhkgg	185	16	novel	novel	JJ
cord-287670-z6ckhkgg	185	17	mechanism	mechanism	NN
cord-287670-z6ckhkgg	185	18	[	[	-LRB-
cord-287670-z6ckhkgg	185	19	5	5	CD
cord-287670-z6ckhkgg	185	20	]	]	-RRB-
cord-287670-z6ckhkgg	185	21	.	.	.
cord-287670-z6ckhkgg	186	1	In	in	IN
cord-287670-z6ckhkgg	186	2	various	various	JJ
cord-287670-z6ckhkgg	186	3	murine	murine	JJ
cord-287670-z6ckhkgg	186	4	models	model	NNS
cord-287670-z6ckhkgg	186	5	of	of	IN
cord-287670-z6ckhkgg	186	6	tissue	tissue	NN
cord-287670-z6ckhkgg	186	7	damage	damage	NN
cord-287670-z6ckhkgg	186	8	,	,	,
cord-287670-z6ckhkgg	186	9	including	include	VBG
cord-287670-z6ckhkgg	186	10	skin	skin	NN
cord-287670-z6ckhkgg	186	11	-	-	HYPH
cord-287670-z6ckhkgg	186	12	wound	wound	NN
cord-287670-z6ckhkgg	186	13	healing	healing	NN
cord-287670-z6ckhkgg	186	14	,	,	,
cord-287670-z6ckhkgg	186	15	chemically	chemically	RB
cord-287670-z6ckhkgg	186	16	induced	induce	VBN
cord-287670-z6ckhkgg	186	17	sterile	sterile	JJ
cord-287670-z6ckhkgg	186	18	liver	liver	NN
cord-287670-z6ckhkgg	186	19	and	and	CC
cord-287670-z6ckhkgg	186	20	lung	lung	NN
cord-287670-z6ckhkgg	186	21	injury	injury	NN
cord-287670-z6ckhkgg	186	22	and	and	CC
cord-287670-z6ckhkgg	186	23	arterial	arterial	JJ
cord-287670-z6ckhkgg	186	24	thrombosis	thrombosis	NN
cord-287670-z6ckhkgg	186	25	,	,	,
cord-287670-z6ckhkgg	186	26	global	global	JJ
cord-287670-z6ckhkgg	186	27	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	186	28	deficiency	deficiency	NN
cord-287670-z6ckhkgg	186	29	was	be	VBD
cord-287670-z6ckhkgg	186	30	associated	associate	VBN
cord-287670-z6ckhkgg	186	31	with	with	IN
cord-287670-z6ckhkgg	186	32	increased	increase	VBN
cord-287670-z6ckhkgg	186	33	clot	clot	NN
cord-287670-z6ckhkgg	186	34	formation	formation	NN
cord-287670-z6ckhkgg	186	35	as	as	RB
cord-287670-z6ckhkgg	186	36	well	well	RB
cord-287670-z6ckhkgg	186	37	as	as	IN
cord-287670-z6ckhkgg	186	38	with	with	IN
cord-287670-z6ckhkgg	186	39	fibrin	fibrin	NN
cord-287670-z6ckhkgg	186	40	and	and	CC
cord-287670-z6ckhkgg	186	41	collagen	collagen	NN
cord-287670-z6ckhkgg	186	42	deposition/	deposition/	NN
cord-287670-z6ckhkgg	186	43	persistence	persistence	NN
cord-287670-z6ckhkgg	186	44	in	in	IN
cord-287670-z6ckhkgg	186	45	sites	site	NNS
cord-287670-z6ckhkgg	186	46	of	of	IN
cord-287670-z6ckhkgg	186	47	tissue	tissue	NN
cord-287670-z6ckhkgg	186	48	damage	damage	NN
cord-287670-z6ckhkgg	186	49	.	.	.
cord-287670-z6ckhkgg	187	1	Under	under	IN
cord-287670-z6ckhkgg	187	2	these	these	DT
cord-287670-z6ckhkgg	187	3	conditions	condition	NNS
cord-287670-z6ckhkgg	187	4	,	,	,
cord-287670-z6ckhkgg	187	5	macrophages	macrophage	NNS
cord-287670-z6ckhkgg	187	6	and	and	CC
cord-287670-z6ckhkgg	187	7	mesenchymal	mesenchymal	JJ
cord-287670-z6ckhkgg	187	8	cells	cell	NNS
cord-287670-z6ckhkgg	187	9	produced	produce	VBD
cord-287670-z6ckhkgg	187	10	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	187	11	in	in	IN
cord-287670-z6ckhkgg	187	12	response	response	NN
cord-287670-z6ckhkgg	187	13	to	to	IN
cord-287670-z6ckhkgg	187	14	TLR	TLR	NNP
cord-287670-z6ckhkgg	187	15	activation	activation	NN
cord-287670-z6ckhkgg	187	16	and	and	CC
cord-287670-z6ckhkgg	187	17	amplification	amplification	NN
cord-287670-z6ckhkgg	187	18	by	by	IN
cord-287670-z6ckhkgg	187	19	IL-1	IL-1	NNP
cord-287670-z6ckhkgg	187	20	,	,	,
cord-287670-z6ckhkgg	187	21	localizing	localize	VBG
cord-287670-z6ckhkgg	187	22	to	to	IN
cord-287670-z6ckhkgg	187	23	the	the	DT
cord-287670-z6ckhkgg	187	24	pericellular	pericellular	JJ
cord-287670-z6ckhkgg	187	25	matrix	matrix	NN
cord-287670-z6ckhkgg	187	26	of	of	IN
cord-287670-z6ckhkgg	187	27	macrophages	macrophage	NNS
cord-287670-z6ckhkgg	187	28	and	and	CC
cord-287670-z6ckhkgg	187	29	mesenchymal	mesenchymal	JJ
cord-287670-z6ckhkgg	187	30	remodeling	remodeling	NN
cord-287670-z6ckhkgg	187	31	cells	cell	NNS
cord-287670-z6ckhkgg	187	32	[	[	-LRB-
cord-287670-z6ckhkgg	187	33	5	5	CD
cord-287670-z6ckhkgg	187	34	]	]	-RRB-
cord-287670-z6ckhkgg	187	35	.	.	.
cord-287670-z6ckhkgg	188	1	Moreover	moreover	RB
cord-287670-z6ckhkgg	188	2	,	,	,
cord-287670-z6ckhkgg	188	3	PTX3deficient	PTX3deficient	NNP
cord-287670-z6ckhkgg	188	4	mesenchymal	mesenchymal	JJ
cord-287670-z6ckhkgg	188	5	remodeling	remodeling	NN
cord-287670-z6ckhkgg	188	6	cells	cell	NNS
cord-287670-z6ckhkgg	188	7	exhibited	exhibit	VBD
cord-287670-z6ckhkgg	188	8	defective	defective	JJ
cord-287670-z6ckhkgg	188	9	pericellular	pericellular	FW
cord-287670-z6ckhkgg	188	10	fibrinolysis	fibrinolysis	NN
cord-287670-z6ckhkgg	188	11	in	in	IN
cord-287670-z6ckhkgg	188	12	vitro	vitro	FW
cord-287670-z6ckhkgg	188	13	and	and	CC
cord-287670-z6ckhkgg	188	14	impaired	impair	VBN
cord-287670-z6ckhkgg	188	15	directional	directional	JJ
cord-287670-z6ckhkgg	188	16	collective	collective	JJ
cord-287670-z6ckhkgg	188	17	migration	migration	NN
cord-287670-z6ckhkgg	188	18	in	in	IN
cord-287670-z6ckhkgg	188	19	the	the	DT
cord-287670-z6ckhkgg	188	20	provisional	provisional	JJ
cord-287670-z6ckhkgg	188	21	fibrin	fibrin	NN
cord-287670-z6ckhkgg	188	22	-	-	HYPH
cord-287670-z6ckhkgg	188	23	rich	rich	JJ
cord-287670-z6ckhkgg	188	24	inflammatory	inflammatory	JJ
cord-287670-z6ckhkgg	188	25	matrix	matrix	NN
cord-287670-z6ckhkgg	188	26	in	in	IN
cord-287670-z6ckhkgg	188	27	mice	mouse	NNS
cord-287670-z6ckhkgg	188	28	in	in	IN
cord-287670-z6ckhkgg	188	29	vivo	vivo	NNP
cord-287670-z6ckhkgg	188	30	.	.	.
cord-287670-z6ckhkgg	189	1	It	-PRON-	PRP
cord-287670-z6ckhkgg	189	2	was	be	VBD
cord-287670-z6ckhkgg	189	3	proposed	propose	VBN
cord-287670-z6ckhkgg	189	4	that	that	IN
cord-287670-z6ckhkgg	189	5	this	this	DT
cord-287670-z6ckhkgg	189	6	phenotype	phenotype	NN
cord-287670-z6ckhkgg	189	7	resulted	result	VBD
cord-287670-z6ckhkgg	189	8	from	from	IN
cord-287670-z6ckhkgg	189	9	the	the	DT
cord-287670-z6ckhkgg	189	10	interaction	interaction	NN
cord-287670-z6ckhkgg	189	11	of	of	IN
cord-287670-z6ckhkgg	189	12	the	the	DT
cord-287670-z6ckhkgg	189	13	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	189	14	N	N	NNP
cord-287670-z6ckhkgg	189	15	-	-	HYPH
cord-287670-z6ckhkgg	189	16	terminal	terminal	NN
cord-287670-z6ckhkgg	189	17	domain	domain	NN
cord-287670-z6ckhkgg	189	18	with	with	IN
cord-287670-z6ckhkgg	189	19	fibrin	fibrin	NN
cord-287670-z6ckhkgg	189	20	and	and	CC
cord-287670-z6ckhkgg	189	21	plasminogen	plasminogen	NN
cord-287670-z6ckhkgg	189	22	proteins	protein	NNS
cord-287670-z6ckhkgg	189	23	at	at	IN
cord-287670-z6ckhkgg	189	24	an	an	DT
cord-287670-z6ckhkgg	189	25	acidic	acidic	JJ
cord-287670-z6ckhkgg	189	26	pH	ph	NN
cord-287670-z6ckhkgg	189	27	and	and	CC
cord-287670-z6ckhkgg	189	28	that	that	IN
cord-287670-z6ckhkgg	189	29	this	this	DT
cord-287670-z6ckhkgg	189	30	occurred	occur	VBD
cord-287670-z6ckhkgg	189	31	in	in	IN
cord-287670-z6ckhkgg	189	32	vivo	vivo	NN
cord-287670-z6ckhkgg	189	33	as	as	IN
cord-287670-z6ckhkgg	189	34	a	a	DT
cord-287670-z6ckhkgg	189	35	consequence	consequence	NN
cord-287670-z6ckhkgg	189	36	of	of	IN
cord-287670-z6ckhkgg	189	37	cell	cell	NN
cord-287670-z6ckhkgg	189	38	metabolic	metabolic	JJ
cord-287670-z6ckhkgg	189	39	adaptation	adaptation	NN
cord-287670-z6ckhkgg	189	40	under	under	IN
cord-287670-z6ckhkgg	189	41	conditions	condition	NNS
cord-287670-z6ckhkgg	189	42	of	of	IN
cord-287670-z6ckhkgg	189	43	tissue	tissue	NN
cord-287670-z6ckhkgg	189	44	damage	damage	NN
cord-287670-z6ckhkgg	189	45	-	-	HYPH
cord-287670-z6ckhkgg	189	46	associated	associate	VBN
cord-287670-z6ckhkgg	189	47	hypoperfusion	hypoperfusion	NN
cord-287670-z6ckhkgg	189	48	and	and	CC
cord-287670-z6ckhkgg	189	49	hypoxia	hypoxia	NN
cord-287670-z6ckhkgg	189	50	[	[	-LRB-
cord-287670-z6ckhkgg	189	51	5	5	CD
cord-287670-z6ckhkgg	189	52	]	]	-RRB-
cord-287670-z6ckhkgg	189	53	.	.	.
cord-287670-z6ckhkgg	190	1	Furthermore	furthermore	RB
cord-287670-z6ckhkgg	190	2	,	,	,
cord-287670-z6ckhkgg	190	3	this	this	DT
cord-287670-z6ckhkgg	190	4	work	work	NN
cord-287670-z6ckhkgg	190	5	argued	argue	VBD
cord-287670-z6ckhkgg	190	6	that	that	IN
cord-287670-z6ckhkgg	190	7	the	the	DT
cord-287670-z6ckhkgg	190	8	tripartite	tripartite	JJ
cord-287670-z6ckhkgg	190	9	interaction	interaction	NN
cord-287670-z6ckhkgg	190	10	between	between	IN
cord-287670-z6ckhkgg	190	11	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	190	12	,	,	,
cord-287670-z6ckhkgg	190	13	fibrin	fibrin	NN
cord-287670-z6ckhkgg	190	14	,	,	,
cord-287670-z6ckhkgg	190	15	and	and	CC
cord-287670-z6ckhkgg	190	16	plasminogen	plasminogen	NN
cord-287670-z6ckhkgg	190	17	at	at	IN
cord-287670-z6ckhkgg	190	18	sites	site	NNS
cord-287670-z6ckhkgg	190	19	of	of	IN
cord-287670-z6ckhkgg	190	20	tissue	tissue	NN
cord-287670-z6ckhkgg	190	21	repair	repair	NN
cord-287670-z6ckhkgg	190	22	facilitated	facilitate	VBN
cord-287670-z6ckhkgg	190	23	plasminogen	plasminogen	NN
cord-287670-z6ckhkgg	190	24	-	-	HYPH
cord-287670-z6ckhkgg	190	25	dependent	dependent	JJ
cord-287670-z6ckhkgg	190	26	fibrinolysis	fibrinolysis	NN
cord-287670-z6ckhkgg	190	27	[	[	-LRB-
cord-287670-z6ckhkgg	190	28	5	5	CD
cord-287670-z6ckhkgg	190	29	]	]	-RRB-
cord-287670-z6ckhkgg	190	30	.	.	.
cord-287670-z6ckhkgg	191	1	Deposited	deposit	VBN
cord-287670-z6ckhkgg	191	2	fibrin	fibrin	NN
cord-287670-z6ckhkgg	191	3	in	in	IN
cord-287670-z6ckhkgg	191	4	damaged	damage	VBN
cord-287670-z6ckhkgg	191	5	tissues	tissue	NNS
cord-287670-z6ckhkgg	191	6	acts	act	VBZ
cord-287670-z6ckhkgg	191	7	as	as	IN
cord-287670-z6ckhkgg	191	8	a	a	DT
cord-287670-z6ckhkgg	191	9	provisional	provisional	JJ
cord-287670-z6ckhkgg	191	10	matrix	matrix	NN
cord-287670-z6ckhkgg	191	11	component	component	NN
cord-287670-z6ckhkgg	191	12	and	and	CC
cord-287670-z6ckhkgg	191	13	its	-PRON-	PRP$
cord-287670-z6ckhkgg	191	14	timely	timely	JJ
cord-287670-z6ckhkgg	191	15	remodeling	remodeling	NN
cord-287670-z6ckhkgg	191	16	is	be	VBZ
cord-287670-z6ckhkgg	191	17	essential	essential	JJ
cord-287670-z6ckhkgg	191	18	for	for	IN
cord-287670-z6ckhkgg	191	19	normal	normal	JJ
cord-287670-z6ckhkgg	191	20	tissue	tissue	NN
cord-287670-z6ckhkgg	191	21	repair	repair	NN
cord-287670-z6ckhkgg	191	22	[	[	-LRB-
cord-287670-z6ckhkgg	191	23	67	67	CD
cord-287670-z6ckhkgg	191	24	]	]	-RRB-
cord-287670-z6ckhkgg	191	25	.	.	.
cord-287670-z6ckhkgg	192	1	Consequently	consequently	RB
cord-287670-z6ckhkgg	192	2	,	,	,
cord-287670-z6ckhkgg	192	3	the	the	DT
cord-287670-z6ckhkgg	192	4	phenotype	phenotype	NN
cord-287670-z6ckhkgg	192	5	of	of	IN
cord-287670-z6ckhkgg	192	6	Ptx3	Ptx3	NNP
cord-287670-z6ckhkgg	192	7	À	à	NN
cord-287670-z6ckhkgg	192	8	/	/	SYM
cord-287670-z6ckhkgg	192	9	À	à	NN
cord-287670-z6ckhkgg	192	10	mice	mouse	NNS
cord-287670-z6ckhkgg	192	11	described	describe	VBN
cord-287670-z6ckhkgg	192	12	by	by	IN
cord-287670-z6ckhkgg	192	13	Doni	Doni	NNP
cord-287670-z6ckhkgg	192	14	et	et	FW
cord-287670-z6ckhkgg	192	15	al	al	NNP
cord-287670-z6ckhkgg	192	16	.	.	.
cord-287670-z6ckhkgg	193	1	[	[	-LRB-
cord-287670-z6ckhkgg	193	2	5	5	LS
cord-287670-z6ckhkgg	193	3	]	]	-RRB-
cord-287670-z6ckhkgg	193	4	demonstrates	demonstrate	VBZ
cord-287670-z6ckhkgg	193	5	that	that	IN
cord-287670-z6ckhkgg	193	6	the	the	DT
cord-287670-z6ckhkgg	193	7	PTX3-dependent	PTX3-dependent	NNP
cord-287670-z6ckhkgg	193	8	promotion	promotion	NN
cord-287670-z6ckhkgg	193	9	of	of	IN
cord-287670-z6ckhkgg	193	10	fibrin	fibrin	NN
cord-287670-z6ckhkgg	193	11	-	-	HYPH
cord-287670-z6ckhkgg	193	12	rich	rich	JJ
cord-287670-z6ckhkgg	193	13	inflammatory	inflammatory	JJ
cord-287670-z6ckhkgg	193	14	matrix	matrix	NN
cord-287670-z6ckhkgg	193	15	remodeling	remodeling	NN
cord-287670-z6ckhkgg	193	16	contributes	contribute	VBZ
cord-287670-z6ckhkgg	193	17	to	to	IN
cord-287670-z6ckhkgg	193	18	tissue	tissue	NN
cord-287670-z6ckhkgg	193	19	repair	repair	NN
cord-287670-z6ckhkgg	193	20	.	.	.
cord-287670-z6ckhkgg	194	1	Along	along	IN
cord-287670-z6ckhkgg	194	2	the	the	DT
cord-287670-z6ckhkgg	194	3	same	same	JJ
cord-287670-z6ckhkgg	194	4	lines	line	NNS
cord-287670-z6ckhkgg	194	5	,	,	,
cord-287670-z6ckhkgg	194	6	in	in	IN
cord-287670-z6ckhkgg	194	7	another	another	DT
cord-287670-z6ckhkgg	194	8	murine	murine	JJ
cord-287670-z6ckhkgg	194	9	study	study	NN
cord-287670-z6ckhkgg	194	10	PTX3-deficient	ptx3-deficient	NN
cord-287670-z6ckhkgg	194	11	mesenchymal	mesenchymal	JJ
cord-287670-z6ckhkgg	194	12	stromal	stromal	NN
cord-287670-z6ckhkgg	194	13	cells	cell	NNS
cord-287670-z6ckhkgg	194	14	were	be	VBD
cord-287670-z6ckhkgg	194	15	found	find	VBN
cord-287670-z6ckhkgg	194	16	to	to	TO
cord-287670-z6ckhkgg	194	17	be	be	VB
cord-287670-z6ckhkgg	194	18	impaired	impair	VBN
cord-287670-z6ckhkgg	194	19	in	in	IN
cord-287670-z6ckhkgg	194	20	their	-PRON-	PRP$
cord-287670-z6ckhkgg	194	21	ability	ability	NN
cord-287670-z6ckhkgg	194	22	to	to	TO
cord-287670-z6ckhkgg	194	23	promote	promote	VB
cord-287670-z6ckhkgg	194	24	skin	skin	NN
cord-287670-z6ckhkgg	194	25	-	-	HYPH
cord-287670-z6ckhkgg	194	26	wound	wound	NN
cord-287670-z6ckhkgg	194	27	healing	healing	NN
cord-287670-z6ckhkgg	194	28	and	and	CC
cord-287670-z6ckhkgg	194	29	were	be	VBD
cord-287670-z6ckhkgg	194	30	also	also	RB
cord-287670-z6ckhkgg	194	31	associated	associate	VBN
cord-287670-z6ckhkgg	194	32	with	with	IN
cord-287670-z6ckhkgg	194	33	defective	defective	JJ
cord-287670-z6ckhkgg	194	34	pericellular	pericellular	FW
cord-287670-z6ckhkgg	194	35	fibrinolysis	fibrinolysis	NN
cord-287670-z6ckhkgg	194	36	and	and	CC
cord-287670-z6ckhkgg	194	37	cell	cell	NN
cord-287670-z6ckhkgg	194	38	migration	migration	NN
cord-287670-z6ckhkgg	194	39	through	through	IN
cord-287670-z6ckhkgg	194	40	fibrin	fibrin	NN
cord-287670-z6ckhkgg	194	41	[	[	-LRB-
cord-287670-z6ckhkgg	194	42	68	68	CD
cord-287670-z6ckhkgg	194	43	]	]	-RRB-
cord-287670-z6ckhkgg	194	44	.	.	.
cord-287670-z6ckhkgg	195	1	These	these	DT
cord-287670-z6ckhkgg	195	2	studies	study	NNS
cord-287670-z6ckhkgg	195	3	provide	provide	VBP
cord-287670-z6ckhkgg	195	4	further	further	JJ
cord-287670-z6ckhkgg	195	5	evidence	evidence	NN
cord-287670-z6ckhkgg	195	6	of	of	IN
cord-287670-z6ckhkgg	195	7	the	the	DT
cord-287670-z6ckhkgg	195	8	interaction	interaction	NN
cord-287670-z6ckhkgg	195	9	between	between	IN
cord-287670-z6ckhkgg	195	10	humoral	humoral	JJ
cord-287670-z6ckhkgg	195	11	pattern	pattern	NN
cord-287670-z6ckhkgg	195	12	recognition	recognition	NN
cord-287670-z6ckhkgg	195	13	molecules	molecule	NNS
cord-287670-z6ckhkgg	195	14	and	and	CC
cord-287670-z6ckhkgg	195	15	ECM	ECM	NNP
cord-287670-z6ckhkgg	195	16	components	component	NNS
cord-287670-z6ckhkgg	195	17	and	and	CC
cord-287670-z6ckhkgg	195	18	underscore	underscore	VB
cord-287670-z6ckhkgg	195	19	the	the	DT
cord-287670-z6ckhkgg	195	20	evolutionary	evolutionary	JJ
cord-287670-z6ckhkgg	195	21	link	link	NN
cord-287670-z6ckhkgg	195	22	that	that	WDT
cord-287670-z6ckhkgg	195	23	exists	exist	VBZ
cord-287670-z6ckhkgg	195	24	between	between	IN
cord-287670-z6ckhkgg	195	25	microbial	microbial	NN
cord-287670-z6ckhkgg	195	26	and	and	CC
cord-287670-z6ckhkgg	195	27	ECM	ECM	NNP
cord-287670-z6ckhkgg	195	28	recognition	recognition	NN
cord-287670-z6ckhkgg	195	29	in	in	IN
cord-287670-z6ckhkgg	195	30	the	the	DT
cord-287670-z6ckhkgg	195	31	humoral	humoral	JJ
cord-287670-z6ckhkgg	195	32	arm	arm	NN
cord-287670-z6ckhkgg	195	33	of	of	IN
cord-287670-z6ckhkgg	195	34	innate	innate	JJ
cord-287670-z6ckhkgg	195	35	immunity	immunity	NN
cord-287670-z6ckhkgg	195	36	[	[	-LRB-
cord-287670-z6ckhkgg	195	37	3	3	CD
cord-287670-z6ckhkgg	195	38	,	,	,
cord-287670-z6ckhkgg	195	39	69	69	CD
cord-287670-z6ckhkgg	195	40	]	]	-RRB-
cord-287670-z6ckhkgg	195	41	.	.	.
cord-287670-z6ckhkgg	196	1	Regarding	regard	VBG
cord-287670-z6ckhkgg	196	2	the	the	DT
cord-287670-z6ckhkgg	196	3	involvement	involvement	NN
cord-287670-z6ckhkgg	196	4	of	of	IN
cord-287670-z6ckhkgg	196	5	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	196	6	in	in	IN
cord-287670-z6ckhkgg	196	7	inflammatory	inflammatory	JJ
cord-287670-z6ckhkgg	196	8	processes	process	NNS
cord-287670-z6ckhkgg	196	9	,	,	,
cord-287670-z6ckhkgg	196	10	other	other	JJ
cord-287670-z6ckhkgg	196	11	studies	study	NNS
cord-287670-z6ckhkgg	196	12	have	have	VBP
cord-287670-z6ckhkgg	196	13	provided	provide	VBN
cord-287670-z6ckhkgg	196	14	interesting	interesting	JJ
cord-287670-z6ckhkgg	196	15	data	datum	NNS
cord-287670-z6ckhkgg	196	16	.	.	.
cord-287670-z6ckhkgg	197	1	For	for	IN
cord-287670-z6ckhkgg	197	2	example	example	NN
cord-287670-z6ckhkgg	197	3	,	,	,
cord-287670-z6ckhkgg	197	4	in	in	IN
cord-287670-z6ckhkgg	197	5	a	a	DT
cord-287670-z6ckhkgg	197	6	model	model	NN
cord-287670-z6ckhkgg	197	7	of	of	IN
cord-287670-z6ckhkgg	197	8	mouse	mouse	NN
cord-287670-z6ckhkgg	197	9	cardiomyocyte	cardiomyocyte	NNP
cord-287670-z6ckhkgg	197	10	death	death	NN
cord-287670-z6ckhkgg	197	11	resulting	result	VBG
cord-287670-z6ckhkgg	197	12	from	from	IN
cord-287670-z6ckhkgg	197	13	coxsackievirus	coxsackievirus	NNP
cord-287670-z6ckhkgg	197	14	B3	B3	NNP
cord-287670-z6ckhkgg	197	15	(	(	-LRB-
cord-287670-z6ckhkgg	197	16	CVB3	cvb3	JJ
cord-287670-z6ckhkgg	197	17	)	)	-RRB-
cord-287670-z6ckhkgg	197	18	viral	viral	JJ
cord-287670-z6ckhkgg	197	19	infection	infection	NN
cord-287670-z6ckhkgg	197	20	,	,	,
cord-287670-z6ckhkgg	197	21	global	global	JJ
cord-287670-z6ckhkgg	197	22	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	197	23	deficiency	deficiency	NN
cord-287670-z6ckhkgg	197	24	increased	increase	VBD
cord-287670-z6ckhkgg	197	25	heart	heart	NN
cord-287670-z6ckhkgg	197	26	injury	injury	NN
cord-287670-z6ckhkgg	197	27	,	,	,
cord-287670-z6ckhkgg	197	28	as	as	IN
cord-287670-z6ckhkgg	197	29	evidenced	evidence	VBN
cord-287670-z6ckhkgg	197	30	by	by	IN
cord-287670-z6ckhkgg	197	31	increased	increase	VBN
cord-287670-z6ckhkgg	197	32	serum	serum	NN
cord-287670-z6ckhkgg	197	33	creatinine	creatinine	NN
cord-287670-z6ckhkgg	197	34	kinase	kinase	NN
cord-287670-z6ckhkgg	197	35	activity	activity	NN
cord-287670-z6ckhkgg	197	36	and	and	CC
cord-287670-z6ckhkgg	197	37	cardiomyocyte	cardiomyocyte	NN
cord-287670-z6ckhkgg	197	38	apoptosis	apoptosis	NN
cord-287670-z6ckhkgg	197	39	,	,	,
cord-287670-z6ckhkgg	197	40	albeit	albeit	IN
cord-287670-z6ckhkgg	197	41	without	without	IN
cord-287670-z6ckhkgg	197	42	affecting	affect	VBG
cord-287670-z6ckhkgg	197	43	viral	viral	JJ
cord-287670-z6ckhkgg	197	44	titers	titer	NNS
cord-287670-z6ckhkgg	197	45	[	[	-LRB-
cord-287670-z6ckhkgg	197	46	70	70	CD
cord-287670-z6ckhkgg	197	47	]	]	-RRB-
cord-287670-z6ckhkgg	197	48	and	and	CC
cord-287670-z6ckhkgg	197	49	through	through	IN
cord-287670-z6ckhkgg	197	50	a	a	DT
cord-287670-z6ckhkgg	197	51	poorly	poorly	RB
cord-287670-z6ckhkgg	197	52	defined	define	VBN
cord-287670-z6ckhkgg	197	53	mechanism	mechanism	NN
cord-287670-z6ckhkgg	197	54	.	.	.
cord-287670-z6ckhkgg	198	1	In	in	IN
cord-287670-z6ckhkgg	198	2	this	this	DT
cord-287670-z6ckhkgg	198	3	context	context	NN
cord-287670-z6ckhkgg	198	4	,	,	,
cord-287670-z6ckhkgg	198	5	it	-PRON-	PRP
cord-287670-z6ckhkgg	198	6	was	be	VBD
cord-287670-z6ckhkgg	198	7	proposed	propose	VBN
cord-287670-z6ckhkgg	198	8	that	that	IN
cord-287670-z6ckhkgg	198	9	the	the	DT
cord-287670-z6ckhkgg	198	10	catalytic	catalytic	JJ
cord-287670-z6ckhkgg	198	11	activity	activity	NN
cord-287670-z6ckhkgg	198	12	of	of	IN
cord-287670-z6ckhkgg	198	13	the	the	DT
cord-287670-z6ckhkgg	198	14	immunoproteasome	immunoproteasome	NN
cord-287670-z6ckhkgg	198	15	that	that	WDT
cord-287670-z6ckhkgg	198	16	prevents	prevent	VBZ
cord-287670-z6ckhkgg	198	17	exacerbation	exacerbation	NN
cord-287670-z6ckhkgg	198	18	of	of	IN
cord-287670-z6ckhkgg	198	19	CVB3-induced	cvb3-induce	VBN
cord-287670-z6ckhkgg	198	20	myocardial	myocardial	JJ
cord-287670-z6ckhkgg	198	21	destruction	destruction	NN
cord-287670-z6ckhkgg	198	22	regulated	regulate	VBD
cord-287670-z6ckhkgg	198	23	the	the	DT
cord-287670-z6ckhkgg	198	24	timely	timely	JJ
cord-287670-z6ckhkgg	198	25	availability	availability	NN
cord-287670-z6ckhkgg	198	26	of	of	IN
cord-287670-z6ckhkgg	198	27	certain	certain	JJ
cord-287670-z6ckhkgg	198	28	factors	factor	NNS
cord-287670-z6ckhkgg	198	29	(	(	-LRB-
cord-287670-z6ckhkgg	198	30	ERK1/2	ERK1/2	NNP
cord-287670-z6ckhkgg	198	31	and	and	CC
cord-287670-z6ckhkgg	198	32	p38	p38	CD
cord-287670-z6ckhkgg	198	33	)	)	-RRB-
cord-287670-z6ckhkgg	198	34	for	for	IN
cord-287670-z6ckhkgg	198	35	controlling	control	VBG
cord-287670-z6ckhkgg	198	36	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	198	37	mRNA	mRNA	NNP
cord-287670-z6ckhkgg	198	38	expression	expression	NN
cord-287670-z6ckhkgg	198	39	and	and	CC
cord-287670-z6ckhkgg	198	40	protein	protein	NN
cord-287670-z6ckhkgg	198	41	production	production	NN
cord-287670-z6ckhkgg	198	42	during	during	IN
cord-287670-z6ckhkgg	198	43	the	the	DT
cord-287670-z6ckhkgg	198	44	infection	infection	NN
cord-287670-z6ckhkgg	198	45	[	[	-LRB-
cord-287670-z6ckhkgg	198	46	70	70	CD
cord-287670-z6ckhkgg	198	47	]	]	-RRB-
cord-287670-z6ckhkgg	198	48	.	.	.
cord-287670-z6ckhkgg	199	1	This	this	DT
cord-287670-z6ckhkgg	199	2	suggested	suggest	VBD
cord-287670-z6ckhkgg	199	3	that	that	IN
cord-287670-z6ckhkgg	199	4	the	the	DT
cord-287670-z6ckhkgg	199	5	cardioprotective	cardioprotective	JJ
cord-287670-z6ckhkgg	199	6	function	function	NN
cord-287670-z6ckhkgg	199	7	of	of	IN
cord-287670-z6ckhkgg	199	8	immunoproteasome	immunoproteasome	NN
cord-287670-z6ckhkgg	199	9	-	-	HYPH
cord-287670-z6ckhkgg	199	10	dependent	dependent	JJ
cord-287670-z6ckhkgg	199	11	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	199	12	expression	expression	NN
cord-287670-z6ckhkgg	199	13	was	be	VBD
cord-287670-z6ckhkgg	199	14	a	a	DT
cord-287670-z6ckhkgg	199	15	crucial	crucial	JJ
cord-287670-z6ckhkgg	199	16	mechanism	mechanism	NN
cord-287670-z6ckhkgg	199	17	of	of	IN
cord-287670-z6ckhkgg	199	18	stress	stress	NN
cord-287670-z6ckhkgg	199	19	-	-	HYPH
cord-287670-z6ckhkgg	199	20	induced	induce	VBN
cord-287670-z6ckhkgg	199	21	damage	damage	NN
cord-287670-z6ckhkgg	199	22	response	response	NN
cord-287670-z6ckhkgg	199	23	in	in	IN
cord-287670-z6ckhkgg	199	24	myocardial	myocardial	JJ
cord-287670-z6ckhkgg	199	25	inflammation	inflammation	NN
cord-287670-z6ckhkgg	199	26	during	during	IN
cord-287670-z6ckhkgg	199	27	CVB3	cvb3	JJ
cord-287670-z6ckhkgg	199	28	viral	viral	JJ
cord-287670-z6ckhkgg	199	29	infection	infection	NN
cord-287670-z6ckhkgg	199	30	[	[	-LRB-
cord-287670-z6ckhkgg	199	31	70	70	CD
cord-287670-z6ckhkgg	199	32	]	]	-RRB-
cord-287670-z6ckhkgg	199	33	.	.	.
cord-287670-z6ckhkgg	200	1	From	from	IN
cord-287670-z6ckhkgg	200	2	a	a	DT
cord-287670-z6ckhkgg	200	3	different	different	JJ
cord-287670-z6ckhkgg	200	4	perspective	perspective	NN
cord-287670-z6ckhkgg	200	5	,	,	,
cord-287670-z6ckhkgg	200	6	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	200	7	has	have	VBZ
cord-287670-z6ckhkgg	200	8	also	also	RB
cord-287670-z6ckhkgg	200	9	been	be	VBN
cord-287670-z6ckhkgg	200	10	shown	show	VBN
cord-287670-z6ckhkgg	200	11	to	to	TO
cord-287670-z6ckhkgg	200	12	play	play	VB
cord-287670-z6ckhkgg	200	13	a	a	DT
cord-287670-z6ckhkgg	200	14	protective	protective	JJ
cord-287670-z6ckhkgg	200	15	role	role	NN
cord-287670-z6ckhkgg	200	16	in	in	IN
cord-287670-z6ckhkgg	200	17	various	various	JJ
cord-287670-z6ckhkgg	200	18	brain	brain	NN
cord-287670-z6ckhkgg	200	19	disorders	disorder	NNS
cord-287670-z6ckhkgg	200	20	.	.	.
cord-287670-z6ckhkgg	201	1	For	for	IN
cord-287670-z6ckhkgg	201	2	example	example	NN
cord-287670-z6ckhkgg	201	3	,	,	,
cord-287670-z6ckhkgg	201	4	in	in	IN
cord-287670-z6ckhkgg	201	5	a	a	DT
cord-287670-z6ckhkgg	201	6	murine	murine	JJ
cord-287670-z6ckhkgg	201	7	model	model	NN
cord-287670-z6ckhkgg	201	8	of	of	IN
cord-287670-z6ckhkgg	201	9	limbic	limbic	JJ
cord-287670-z6ckhkgg	201	10	seizure	seizure	NN
cord-287670-z6ckhkgg	201	11	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	201	12	synthesis	synthesis	NN
cord-287670-z6ckhkgg	201	13	was	be	VBD
cord-287670-z6ckhkgg	201	14	induced	induce	VBN
cord-287670-z6ckhkgg	201	15	in	in	IN
cord-287670-z6ckhkgg	201	16	the	the	DT
cord-287670-z6ckhkgg	201	17	brain	brain	NN
cord-287670-z6ckhkgg	201	18	,	,	,
cord-287670-z6ckhkgg	201	19	exerting	exert	VBG
cord-287670-z6ckhkgg	201	20	a	a	DT
cord-287670-z6ckhkgg	201	21	protective	protective	JJ
cord-287670-z6ckhkgg	201	22	role	role	NN
cord-287670-z6ckhkgg	201	23	in	in	IN
cord-287670-z6ckhkgg	201	24	seizure	seizure	NN
cord-287670-z6ckhkgg	201	25	-	-	HYPH
cord-287670-z6ckhkgg	201	26	induced	induce	VBN
cord-287670-z6ckhkgg	201	27	neurodegeneration	neurodegeneration	NN
cord-287670-z6ckhkgg	201	28	as	as	IN
cord-287670-z6ckhkgg	201	29	evidenced	evidence	VBN
cord-287670-z6ckhkgg	201	30	by	by	IN
cord-287670-z6ckhkgg	201	31	a	a	DT
cord-287670-z6ckhkgg	201	32	lower	low	JJR
cord-287670-z6ckhkgg	201	33	number	number	NN
cord-287670-z6ckhkgg	201	34	of	of	IN
cord-287670-z6ckhkgg	201	35	degenerating	degenerate	VBG
cord-287670-z6ckhkgg	201	36	neurons	neuron	NNS
cord-287670-z6ckhkgg	201	37	in	in	IN
cord-287670-z6ckhkgg	201	38	wild	wild	JJ
cord-287670-z6ckhkgg	201	39	-	-	HYPH
cord-287670-z6ckhkgg	201	40	type	type	NN
cord-287670-z6ckhkgg	201	41	mice	mouse	NNS
cord-287670-z6ckhkgg	201	42	compared	compare	VBN
cord-287670-z6ckhkgg	201	43	with	with	IN
cord-287670-z6ckhkgg	201	44	PTX3-deficient	PTX3-deficient	NNP
cord-287670-z6ckhkgg	201	45	mice	mouse	NNS
cord-287670-z6ckhkgg	201	46	[	[	-LRB-
cord-287670-z6ckhkgg	201	47	71	71	CD
cord-287670-z6ckhkgg	201	48	]	]	-RRB-
cord-287670-z6ckhkgg	201	49	.	.	.
cord-287670-z6ckhkgg	202	1	In	in	IN
cord-287670-z6ckhkgg	202	2	cerebral	cerebral	JJ
cord-287670-z6ckhkgg	202	3	ischemia	ischemia	NN
cord-287670-z6ckhkgg	202	4	mouse	mouse	NN
cord-287670-z6ckhkgg	202	5	models	model	NNS
cord-287670-z6ckhkgg	202	6	,	,	,
cord-287670-z6ckhkgg	202	7	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	202	8	production	production	NN
cord-287670-z6ckhkgg	202	9	was	be	VBD
cord-287670-z6ckhkgg	202	10	induced	induce	VBN
cord-287670-z6ckhkgg	202	11	in	in	IN
cord-287670-z6ckhkgg	202	12	neurons	neuron	NNS
cord-287670-z6ckhkgg	202	13	and	and	CC
cord-287670-z6ckhkgg	202	14	glia	glia	NNS
cord-287670-z6ckhkgg	202	15	,	,	,
cord-287670-z6ckhkgg	202	16	and	and	CC
cord-287670-z6ckhkgg	202	17	although	although	IN
cord-287670-z6ckhkgg	202	18	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	202	19	deficiency	deficiency	NN
cord-287670-z6ckhkgg	202	20	did	do	VBD
cord-287670-z6ckhkgg	202	21	not	not	RB
cord-287670-z6ckhkgg	202	22	affect	affect	VB
cord-287670-z6ckhkgg	202	23	acute	acute	JJ
cord-287670-z6ckhkgg	202	24	ischemic	ischemic	JJ
cord-287670-z6ckhkgg	202	25	brain	brain	NN
cord-287670-z6ckhkgg	202	26	injury	injury	NN
cord-287670-z6ckhkgg	202	27	it	-PRON-	PRP
cord-287670-z6ckhkgg	202	28	did	do	VBD
cord-287670-z6ckhkgg	202	29	,	,	,
cord-287670-z6ckhkgg	202	30	however	however	RB
cord-287670-z6ckhkgg	202	31	,	,	,
cord-287670-z6ckhkgg	202	32	compromise	compromise	JJ
cord-287670-z6ckhkgg	202	33	blood	blood	NN
cord-287670-z6ckhkgg	202	34	-	-	HYPH
cord-287670-z6ckhkgg	202	35	brain	brain	NN
cord-287670-z6ckhkgg	202	36	barrier	barrier	NN
cord-287670-z6ckhkgg	202	37	integrity	integrity	NN
cord-287670-z6ckhkgg	202	38	and	and	CC
cord-287670-z6ckhkgg	202	39	resolution	resolution	NN
cord-287670-z6ckhkgg	202	40	of	of	IN
cord-287670-z6ckhkgg	202	41	brain	brain	NN
cord-287670-z6ckhkgg	202	42	edema	edema	NN
cord-287670-z6ckhkgg	202	43	during	during	IN
cord-287670-z6ckhkgg	202	44	recovery	recovery	NN
cord-287670-z6ckhkgg	202	45	as	as	RB
cord-287670-z6ckhkgg	202	46	well	well	RB
cord-287670-z6ckhkgg	202	47	as	as	IN
cord-287670-z6ckhkgg	202	48	impairing	impair	VBG
cord-287670-z6ckhkgg	202	49	glial	glial	JJ
cord-287670-z6ckhkgg	202	50	scar	scar	NN
cord-287670-z6ckhkgg	202	51	formation	formation	NN
cord-287670-z6ckhkgg	202	52	and	and	CC
cord-287670-z6ckhkgg	202	53	neurogenesis	neurogenesis	NN
cord-287670-z6ckhkgg	202	54	[	[	-LRB-
cord-287670-z6ckhkgg	202	55	72	72	CD
cord-287670-z6ckhkgg	202	56	,	,	,
cord-287670-z6ckhkgg	202	57	73	73	CD
cord-287670-z6ckhkgg	202	58	]	]	-RRB-
cord-287670-z6ckhkgg	202	59	.	.	.
cord-287670-z6ckhkgg	203	1	Thus	thus	RB
cord-287670-z6ckhkgg	203	2	,	,	,
cord-287670-z6ckhkgg	203	3	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	203	4	has	have	VBZ
cord-287670-z6ckhkgg	203	5	been	be	VBN
cord-287670-z6ckhkgg	203	6	proposed	propose	VBN
cord-287670-z6ckhkgg	203	7	to	to	TO
cord-287670-z6ckhkgg	203	8	support	support	VB
cord-287670-z6ckhkgg	203	9	bloodbrain	bloodbrain	NN
cord-287670-z6ckhkgg	203	10	barrier	barrier	NN
cord-287670-z6ckhkgg	203	11	integrity	integrity	NN
cord-287670-z6ckhkgg	203	12	[	[	-LRB-
cord-287670-z6ckhkgg	203	13	74	74	CD
cord-287670-z6ckhkgg	203	14	]	]	-RRB-
cord-287670-z6ckhkgg	203	15	.	.	.
cord-287670-z6ckhkgg	204	1	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	204	2	induction	induction	NN
cord-287670-z6ckhkgg	204	3	in	in	IN
cord-287670-z6ckhkgg	204	4	association	association	NN
cord-287670-z6ckhkgg	204	5	with	with	IN
cord-287670-z6ckhkgg	204	6	tissue	tissue	NN
cord-287670-z6ckhkgg	204	7	damage	damage	NN
cord-287670-z6ckhkgg	204	8	has	have	VBZ
cord-287670-z6ckhkgg	204	9	also	also	RB
cord-287670-z6ckhkgg	204	10	been	be	VBN
cord-287670-z6ckhkgg	204	11	identified	identify	VBN
cord-287670-z6ckhkgg	204	12	in	in	IN
cord-287670-z6ckhkgg	204	13	other	other	JJ
cord-287670-z6ckhkgg	204	14	pathological	pathological	JJ
cord-287670-z6ckhkgg	204	15	contexts	context	NNS
cord-287670-z6ckhkgg	204	16	[	[	-LRB-
cord-287670-z6ckhkgg	204	17	70	70	CD
cord-287670-z6ckhkgg	204	18	]	]	-RRB-
cord-287670-z6ckhkgg	205	1	(	(	-LRB-
cord-287670-z6ckhkgg	205	2	Figure	figure	NN
cord-287670-z6ckhkgg	205	3	3	3	CD
cord-287670-z6ckhkgg	205	4	,	,	,
cord-287670-z6ckhkgg	205	5	Key	Key	NNP
cord-287670-z6ckhkgg	205	6	Figure	Figure	NNP
cord-287670-z6ckhkgg	205	7	)	)	-RRB-
cord-287670-z6ckhkgg	205	8	.	.	.
cord-287670-z6ckhkgg	206	1	For	for	IN
cord-287670-z6ckhkgg	206	2	instance	instance	NN
cord-287670-z6ckhkgg	206	3	,	,	,
cord-287670-z6ckhkgg	206	4	in	in	IN
cord-287670-z6ckhkgg	206	5	a	a	DT
cord-287670-z6ckhkgg	206	6	mouse	mouse	NN
cord-287670-z6ckhkgg	206	7	model	model	NN
cord-287670-z6ckhkgg	206	8	of	of	IN
cord-287670-z6ckhkgg	206	9	superior	superior	JJ
cord-287670-z6ckhkgg	206	10	mesenteric	mesenteric	JJ
cord-287670-z6ckhkgg	206	11	artery	artery	NN
cord-287670-z6ckhkgg	206	12	ischemia	ischemia	NN
cord-287670-z6ckhkgg	206	13	and	and	CC
cord-287670-z6ckhkgg	206	14	reperfusion	reperfusion	NN
cord-287670-z6ckhkgg	206	15	,	,	,
cord-287670-z6ckhkgg	206	16	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	206	17	deficiency	deficiency	NN
cord-287670-z6ckhkgg	206	18	was	be	VBD
cord-287670-z6ckhkgg	206	19	associated	associate	VBN
cord-287670-z6ckhkgg	206	20	with	with	IN
cord-287670-z6ckhkgg	206	21	inhibition	inhibition	NN
cord-287670-z6ckhkgg	206	22	of	of	IN
cord-287670-z6ckhkgg	206	23	local	local	JJ
cord-287670-z6ckhkgg	206	24	and	and	CC
cord-287670-z6ckhkgg	206	25	remote	remote	JJ
cord-287670-z6ckhkgg	206	26	inflammation	inflammation	NN
cord-287670-z6ckhkgg	206	27	and	and	CC
cord-287670-z6ckhkgg	206	28	tissue	tissue	NN
cord-287670-z6ckhkgg	206	29	injury	injury	NN
cord-287670-z6ckhkgg	206	30	,	,	,
cord-287670-z6ckhkgg	206	31	whereas	whereas	IN
cord-287670-z6ckhkgg	206	32	genetic	genetic	JJ
cord-287670-z6ckhkgg	206	33	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	206	34	overexpression	overexpression	NN
cord-287670-z6ckhkgg	206	35	or	or	CC
cord-287670-z6ckhkgg	206	36	i.v	i.v	NNP
cord-287670-z6ckhkgg	206	37	.	.	.
cord-287670-z6ckhkgg	206	38	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	206	39	administration	administration	NN
cord-287670-z6ckhkgg	206	40	worsened	worsen	VBD
cord-287670-z6ckhkgg	206	41	tissue	tissue	NN
cord-287670-z6ckhkgg	206	42	injury	injury	NN
cord-287670-z6ckhkgg	206	43	and	and	CC
cord-287670-z6ckhkgg	206	44	lethality	lethality	NN
cord-287670-z6ckhkgg	206	45	[	[	-LRB-
cord-287670-z6ckhkgg	206	46	75	75	CD
cord-287670-z6ckhkgg	206	47	,	,	,
cord-287670-z6ckhkgg	206	48	76	76	CD
cord-287670-z6ckhkgg	206	49	]	]	-RRB-
cord-287670-z6ckhkgg	206	50	.	.	.
cord-287670-z6ckhkgg	207	1	Accordingly	accordingly	RB
cord-287670-z6ckhkgg	207	2	,	,	,
cord-287670-z6ckhkgg	207	3	in	in	IN
cord-287670-z6ckhkgg	207	4	another	another	DT
cord-287670-z6ckhkgg	207	5	murine	murine	JJ
cord-287670-z6ckhkgg	207	6	study	study	NN
cord-287670-z6ckhkgg	207	7	,	,	,
cord-287670-z6ckhkgg	207	8	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	207	9	overexpression	overexpression	NN
cord-287670-z6ckhkgg	207	10	resulted	result	VBD
cord-287670-z6ckhkgg	207	11	in	in	IN
cord-287670-z6ckhkgg	207	12	increased	increase	VBN
cord-287670-z6ckhkgg	207	13	inflammatory	inflammatory	JJ
cord-287670-z6ckhkgg	207	14	responses	response	NNS
cord-287670-z6ckhkgg	207	15	and	and	CC
cord-287670-z6ckhkgg	207	16	a	a	DT
cord-287670-z6ckhkgg	207	17	faster	fast	JJR
cord-287670-z6ckhkgg	207	18	decline	decline	NN
cord-287670-z6ckhkgg	207	19	in	in	IN
cord-287670-z6ckhkgg	207	20	a	a	DT
cord-287670-z6ckhkgg	207	21	model	model	NN
cord-287670-z6ckhkgg	207	22	of	of	IN
cord-287670-z6ckhkgg	207	23	ventilator	ventilator	NN
cord-287670-z6ckhkgg	207	24	-	-	HYPH
cord-287670-z6ckhkgg	207	25	induced	induce	VBN
cord-287670-z6ckhkgg	207	26	lung	lung	NN
cord-287670-z6ckhkgg	207	27	injury	injury	NN
cord-287670-z6ckhkgg	207	28	[	[	-LRB-
cord-287670-z6ckhkgg	207	29	77	77	CD
cord-287670-z6ckhkgg	207	30	]	]	-RRB-
cord-287670-z6ckhkgg	207	31	.	.	.
cord-287670-z6ckhkgg	208	1	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	208	2	overexpression	overexpression	NN
cord-287670-z6ckhkgg	208	3	also	also	RB
cord-287670-z6ckhkgg	208	4	led	lead	VBD
cord-287670-z6ckhkgg	208	5	to	to	IN
cord-287670-z6ckhkgg	208	6	increased	increase	VBN
cord-287670-z6ckhkgg	208	7	hypertrophic	hypertrophic	JJ
cord-287670-z6ckhkgg	208	8	responses	response	NNS
cord-287670-z6ckhkgg	208	9	and	and	CC
cord-287670-z6ckhkgg	208	10	ventricular	ventricular	JJ
cord-287670-z6ckhkgg	208	11	dysfunction	dysfunction	NN
cord-287670-z6ckhkgg	208	12	following	follow	VBG
cord-287670-z6ckhkgg	208	13	increased	increase	VBN
cord-287670-z6ckhkgg	208	14	pressure	pressure	NN
cord-287670-z6ckhkgg	208	15	overload	overload	NN
cord-287670-z6ckhkgg	208	16	in	in	IN
cord-287670-z6ckhkgg	208	17	a	a	DT
cord-287670-z6ckhkgg	208	18	murine	murine	JJ
cord-287670-z6ckhkgg	208	19	cardiac	cardiac	JJ
cord-287670-z6ckhkgg	208	20	injury	injury	NN
cord-287670-z6ckhkgg	208	21	model	model	NN
cord-287670-z6ckhkgg	208	22	[	[	-LRB-
cord-287670-z6ckhkgg	208	23	78	78	CD
cord-287670-z6ckhkgg	208	24	]	]	-RRB-
cord-287670-z6ckhkgg	208	25	.	.	.
cord-287670-z6ckhkgg	209	1	More	more	RBR
cord-287670-z6ckhkgg	209	2	recently	recently	RB
cord-287670-z6ckhkgg	209	3	,	,	,
cord-287670-z6ckhkgg	209	4	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	209	5	has	have	VBZ
cord-287670-z6ckhkgg	209	6	been	be	VBN
cord-287670-z6ckhkgg	209	7	found	find	VBN
cord-287670-z6ckhkgg	209	8	to	to	TO
cord-287670-z6ckhkgg	209	9	induce	induce	VB
cord-287670-z6ckhkgg	209	10	mouse	mouse	NN
cord-287670-z6ckhkgg	209	11	EC	EC	NNP
cord-287670-z6ckhkgg	209	12	dysfunction	dysfunction	NN
cord-287670-z6ckhkgg	209	13	by	by	IN
cord-287670-z6ckhkgg	209	14	inhibiting	inhibit	VBG
cord-287670-z6ckhkgg	209	15	acetylcholine	acetylcholine	NN
cord-287670-z6ckhkgg	209	16	-	-	HYPH
cord-287670-z6ckhkgg	209	17	evoked	evoke	VBN
cord-287670-z6ckhkgg	209	18	vasorelaxation	vasorelaxation	NN
cord-287670-z6ckhkgg	209	19	in	in	IN
cord-287670-z6ckhkgg	209	20	an	an	DT
cord-287670-z6ckhkgg	209	21	in	in	FW
cord-287670-z6ckhkgg	209	22	vitro	vitro	FW
cord-287670-z6ckhkgg	209	23	model	model	NN
cord-287670-z6ckhkgg	209	24	of	of	IN
cord-287670-z6ckhkgg	209	25	the	the	DT
cord-287670-z6ckhkgg	209	26	vascular	vascular	JJ
cord-287670-z6ckhkgg	209	27	reactivity	reactivity	NN
cord-287670-z6ckhkgg	209	28	of	of	IN
cord-287670-z6ckhkgg	209	29	resistance	resistance	NN
cord-287670-z6ckhkgg	209	30	vessels	vessel	NNS
cord-287670-z6ckhkgg	209	31	and	and	CC
cord-287670-z6ckhkgg	209	32	by	by	IN
cord-287670-z6ckhkgg	209	33	inducing	induce	VBG
cord-287670-z6ckhkgg	209	34	morphological	morphological	JJ
cord-287670-z6ckhkgg	209	35	changes	change	NNS
cord-287670-z6ckhkgg	209	36	in	in	IN
cord-287670-z6ckhkgg	209	37	ECs	ec	NNS
cord-287670-z6ckhkgg	209	38	[	[	-LRB-
cord-287670-z6ckhkgg	209	39	79	79	CD
cord-287670-z6ckhkgg	209	40	]	]	-RRB-
cord-287670-z6ckhkgg	209	41	.	.	.
cord-287670-z6ckhkgg	210	1	These	these	DT
cord-287670-z6ckhkgg	210	2	effects	effect	NNS
cord-287670-z6ckhkgg	210	3	were	be	VBD
cord-287670-z6ckhkgg	210	4	The	the	DT
cord-287670-z6ckhkgg	210	5	Yin	Yin	NNP
cord-287670-z6ckhkgg	210	6	-	-	HYPH
cord-287670-z6ckhkgg	210	7	Yang	Yang	NNP
cord-287670-z6ckhkgg	210	8	of	of	IN
cord-287670-z6ckhkgg	210	9	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	210	10	in	in	IN
cord-287670-z6ckhkgg	210	11	Innate	Innate	NNP
cord-287670-z6ckhkgg	210	12	Immunity	Immunity	NNP
cord-287670-z6ckhkgg	210	13	,	,	,
cord-287670-z6ckhkgg	210	14	Inflammation	inflammation	NN
cord-287670-z6ckhkgg	210	15	,	,	,
cord-287670-z6ckhkgg	210	16	Tissue	tissue	NN
cord-287670-z6ckhkgg	210	17	Damage	damage	NN
cord-287670-z6ckhkgg	210	18	,	,	,
cord-287670-z6ckhkgg	210	19	and	and	CC
cord-287670-z6ckhkgg	210	20	Cancer	Cancer	NNP
cord-287670-z6ckhkgg	210	21	reported	report	VBD
cord-287670-z6ckhkgg	210	22	to	to	TO
cord-287670-z6ckhkgg	210	23	be	be	VB
cord-287670-z6ckhkgg	210	24	mediated	mediate	VBN
cord-287670-z6ckhkgg	210	25	by	by	IN
cord-287670-z6ckhkgg	210	26	a	a	DT
cord-287670-z6ckhkgg	210	27	P	p	NN
cord-287670-z6ckhkgg	210	28	-	-	HYPH
cord-287670-z6ckhkgg	210	29	selectin	selectin	NN
cord-287670-z6ckhkgg	210	30	/	/	SYM
cord-287670-z6ckhkgg	210	31	matrix	matrix	NN
cord-287670-z6ckhkgg	210	32	metalloproteinase-1-dependent	metalloproteinase-1-dependent	NNP
cord-287670-z6ckhkgg	210	33	pathway	pathway	NN
cord-287670-z6ckhkgg	210	34	leading	lead	VBG
cord-287670-z6ckhkgg	210	35	to	to	IN
cord-287670-z6ckhkgg	210	36	impaired	impaired	JJ
cord-287670-z6ckhkgg	210	37	phosphorylation	phosphorylation	NN
cord-287670-z6ckhkgg	210	38	of	of	IN
cord-287670-z6ckhkgg	210	39	eNOS	enos	JJ
cord-287670-z6ckhkgg	210	40	and	and	CC
cord-287670-z6ckhkgg	210	41	nitric	nitric	JJ
cord-287670-z6ckhkgg	210	42	oxide	oxide	NN
cord-287670-z6ckhkgg	210	43	production	production	NN
cord-287670-z6ckhkgg	210	44	in	in	IN
cord-287670-z6ckhkgg	210	45	vitro	vitro	FW
cord-287670-z6ckhkgg	210	46	[	[	-LRB-
cord-287670-z6ckhkgg	210	47	79	79	CD
cord-287670-z6ckhkgg	210	48	]	]	-RRB-
cord-287670-z6ckhkgg	210	49	.	.	.
cord-287670-z6ckhkgg	211	1	In	in	IN
cord-287670-z6ckhkgg	211	2	agreement	agreement	NN
cord-287670-z6ckhkgg	211	3	,	,	,
cord-287670-z6ckhkgg	211	4	i.v	i.v	NNP
cord-287670-z6ckhkgg	211	5	.	.	.
cord-287670-z6ckhkgg	211	6	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	211	7	administration	administration	NN
cord-287670-z6ckhkgg	211	8	caused	cause	VBD
cord-287670-z6ckhkgg	211	9	hypertension	hypertension	NN
cord-287670-z6ckhkgg	211	10	in	in	IN
cord-287670-z6ckhkgg	211	11	wild	wild	JJ
cord-287670-z6ckhkgg	211	12	-	-	HYPH
cord-287670-z6ckhkgg	211	13	type	type	NN
cord-287670-z6ckhkgg	211	14	animals	animal	NNS
cord-287670-z6ckhkgg	211	15	but	but	CC
cord-287670-z6ckhkgg	211	16	not	not	RB
cord-287670-z6ckhkgg	211	17	in	in	IN
cord-287670-z6ckhkgg	211	18	P	p	NN
cord-287670-z6ckhkgg	211	19	-	-	HYPH
cord-287670-z6ckhkgg	211	20	selectin	selectin	NN
cord-287670-z6ckhkgg	211	21	-	-	HYPH
cord-287670-z6ckhkgg	211	22	deficient	deficient	JJ
cord-287670-z6ckhkgg	211	23	mice	mouse	NNS
cord-287670-z6ckhkgg	211	24	[	[	-LRB-
cord-287670-z6ckhkgg	211	25	79	79	CD
cord-287670-z6ckhkgg	211	26	]	]	-RRB-
cord-287670-z6ckhkgg	211	27	.	.	.
cord-287670-z6ckhkgg	212	1	These	these	DT
cord-287670-z6ckhkgg	212	2	results	result	NNS
cord-287670-z6ckhkgg	212	3	suggest	suggest	VBP
cord-287670-z6ckhkgg	212	4	that	that	IN
cord-287670-z6ckhkgg	212	5	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	212	6	may	may	MD
cord-287670-z6ckhkgg	212	7	have	have	VB
cord-287670-z6ckhkgg	212	8	a	a	DT
cord-287670-z6ckhkgg	212	9	possible	possible	JJ
cord-287670-z6ckhkgg	212	10	direct	direct	JJ
cord-287670-z6ckhkgg	212	11	role	role	NN
cord-287670-z6ckhkgg	212	12	on	on	IN
cord-287670-z6ckhkgg	212	13	blood	blood	NN
cord-287670-z6ckhkgg	212	14	pressure	pressure	NN
cord-287670-z6ckhkgg	212	15	homeostasis	homeostasis	NN
cord-287670-z6ckhkgg	212	16	and	and	CC
cord-287670-z6ckhkgg	212	17	endothelial	endothelial	JJ
cord-287670-z6ckhkgg	212	18	function	function	NN
cord-287670-z6ckhkgg	212	19	.	.	.
cord-287670-z6ckhkgg	213	1	Inflammation	inflammation	NN
cord-287670-z6ckhkgg	213	2	is	be	VBZ
cord-287670-z6ckhkgg	213	3	an	an	DT
cord-287670-z6ckhkgg	213	4	essential	essential	JJ
cord-287670-z6ckhkgg	213	5	component	component	NN
cord-287670-z6ckhkgg	213	6	of	of	IN
cord-287670-z6ckhkgg	213	7	tumor	tumor	NN
cord-287670-z6ckhkgg	213	8	microenvironments	microenvironment	NNS
cord-287670-z6ckhkgg	213	9	in	in	IN
cord-287670-z6ckhkgg	213	10	cancer	cancer	NN
cord-287670-z6ckhkgg	213	11	,	,	,
cord-287670-z6ckhkgg	213	12	sustaining	sustain	VBG
cord-287670-z6ckhkgg	213	13	tumor	tumor	NN
cord-287670-z6ckhkgg	213	14	development	development	NN
cord-287670-z6ckhkgg	213	15	and	and	CC
cord-287670-z6ckhkgg	213	16	growth	growth	NN
cord-287670-z6ckhkgg	213	17	[	[	-LRB-
cord-287670-z6ckhkgg	213	18	80	80	CD
cord-287670-z6ckhkgg	213	19	]	]	-RRB-
cord-287670-z6ckhkgg	213	20	.	.	.
cord-287670-z6ckhkgg	214	1	However	however	RB
cord-287670-z6ckhkgg	214	2	,	,	,
cord-287670-z6ckhkgg	214	3	the	the	DT
cord-287670-z6ckhkgg	214	4	role	role	NN
cord-287670-z6ckhkgg	214	5	of	of	IN
cord-287670-z6ckhkgg	214	6	the	the	DT
cord-287670-z6ckhkgg	214	7	humoral	humoral	JJ
cord-287670-z6ckhkgg	214	8	arm	arm	NN
cord-287670-z6ckhkgg	214	9	of	of	IN
cord-287670-z6ckhkgg	214	10	the	the	DT
cord-287670-z6ckhkgg	214	11	innate	innate	JJ
cord-287670-z6ckhkgg	214	12	immune	immune	JJ
cord-287670-z6ckhkgg	214	13	system	system	NN
cord-287670-z6ckhkgg	214	14	in	in	IN
cord-287670-z6ckhkgg	214	15	cancer	cancer	NN
cord-287670-z6ckhkgg	214	16	is	be	VBZ
cord-287670-z6ckhkgg	214	17	poorly	poorly	RB
cord-287670-z6ckhkgg	214	18	understood	understand	VBN
cord-287670-z6ckhkgg	214	19	.	.	.
cord-287670-z6ckhkgg	215	1	Various	various	JJ
cord-287670-z6ckhkgg	215	2	reports	report	NNS
cord-287670-z6ckhkgg	215	3	have	have	VBP
cord-287670-z6ckhkgg	215	4	associated	associate	VBN
cord-287670-z6ckhkgg	215	5	increased	increase	VBN
cord-287670-z6ckhkgg	215	6	plasma	plasma	NN
cord-287670-z6ckhkgg	215	7	levels	level	NNS
cord-287670-z6ckhkgg	215	8	of	of	IN
cord-287670-z6ckhkgg	215	9	CRP	CRP	NNP
cord-287670-z6ckhkgg	215	10	with	with	IN
cord-287670-z6ckhkgg	215	11	cancer	cancer	NN
cord-287670-z6ckhkgg	215	12	risk	risk	NN
cord-287670-z6ckhkgg	215	13	[	[	-LRB-
cord-287670-z6ckhkgg	215	14	81	81	CD
cord-287670-z6ckhkgg	215	15	]	]	-RRB-
cord-287670-z6ckhkgg	215	16	[	[	-LRB-
cord-287670-z6ckhkgg	215	17	82	82	CD
cord-287670-z6ckhkgg	215	18	]	]	-RRB-
cord-287670-z6ckhkgg	215	19	[	[	-LRB-
cord-287670-z6ckhkgg	215	20	83	83	CD
cord-287670-z6ckhkgg	215	21	]	]	-RRB-
cord-287670-z6ckhkgg	215	22	.	.	.
cord-287670-z6ckhkgg	216	1	Furthermore	furthermore	RB
cord-287670-z6ckhkgg	216	2	,	,	,
cord-287670-z6ckhkgg	216	3	elevated	elevate	VBN
cord-287670-z6ckhkgg	216	4	local	local	JJ
cord-287670-z6ckhkgg	216	5	or	or	CC
cord-287670-z6ckhkgg	216	6	systemic	systemic	JJ
cord-287670-z6ckhkgg	216	7	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	216	8	levels	level	NNS
cord-287670-z6ckhkgg	216	9	have	have	VBP
cord-287670-z6ckhkgg	216	10	been	be	VBN
cord-287670-z6ckhkgg	216	11	observed	observe	VBN
cord-287670-z6ckhkgg	216	12	for	for	IN
cord-287670-z6ckhkgg	216	13	several	several	JJ
cord-287670-z6ckhkgg	216	14	cancers	cancer	NNS
cord-287670-z6ckhkgg	216	15	,	,	,
cord-287670-z6ckhkgg	216	16	including	include	VBG
cord-287670-z6ckhkgg	216	17	glioma	glioma	NN
cord-287670-z6ckhkgg	216	18	,	,	,
cord-287670-z6ckhkgg	216	19	liposarcoma	liposarcoma	NNP
cord-287670-z6ckhkgg	216	20	,	,	,
cord-287670-z6ckhkgg	216	21	lung	lung	NN
cord-287670-z6ckhkgg	216	22	cancer	cancer	NN
cord-287670-z6ckhkgg	216	23	,	,	,
cord-287670-z6ckhkgg	216	24	prostate	prostate	NN
cord-287670-z6ckhkgg	216	25	carcinoma	carcinoma	NN
cord-287670-z6ckhkgg	216	26	,	,	,
cord-287670-z6ckhkgg	216	27	pancreatic	pancreatic	JJ
cord-287670-z6ckhkgg	216	28	carcinoma	carcinoma	NN
cord-287670-z6ckhkgg	216	29	,	,	,
cord-287670-z6ckhkgg	216	30	and	and	CC
cord-287670-z6ckhkgg	216	31	breast	breast	NN
cord-287670-z6ckhkgg	216	32	cancer	cancer	NN
cord-287670-z6ckhkgg	216	33	bone	bone	NN
cord-287670-z6ckhkgg	216	34	metastases	metastasis	NNS
cord-287670-z6ckhkgg	216	35	,	,	,
cord-287670-z6ckhkgg	216	36	that	that	WDT
cord-287670-z6ckhkgg	216	37	correlate	correlate	VBP
cord-287670-z6ckhkgg	216	38	with	with	IN
cord-287670-z6ckhkgg	216	39	either	either	DT
cord-287670-z6ckhkgg	216	40	grade	grade	NN
cord-287670-z6ckhkgg	216	41	of	of	IN
cord-287670-z6ckhkgg	216	42	malignancy	malignancy	NN
cord-287670-z6ckhkgg	216	43	or	or	CC
cord-287670-z6ckhkgg	216	44	a	a	DT
cord-287670-z6ckhkgg	216	45	poor	poor	JJ
cord-287670-z6ckhkgg	216	46	prognosis	prognosis	NN
cord-287670-z6ckhkgg	216	47	[	[	-LRB-
cord-287670-z6ckhkgg	216	48	18	18	CD
cord-287670-z6ckhkgg	216	49	,	,	,
cord-287670-z6ckhkgg	216	50	[	[	-LRB-
cord-287670-z6ckhkgg	216	51	84	84	CD
cord-287670-z6ckhkgg	216	52	]	]	-RRB-
cord-287670-z6ckhkgg	216	53	[	[	-LRB-
cord-287670-z6ckhkgg	216	54	85	85	CD
cord-287670-z6ckhkgg	216	55	]	]	-RRB-
cord-287670-z6ckhkgg	216	56	[	[	-LRB-
cord-287670-z6ckhkgg	216	57	86	86	CD
cord-287670-z6ckhkgg	216	58	]	]	-RRB-
cord-287670-z6ckhkgg	216	59	[	[	-LRB-
cord-287670-z6ckhkgg	216	60	87	87	CD
cord-287670-z6ckhkgg	216	61	]	]	-RRB-
cord-287670-z6ckhkgg	216	62	[	[	-LRB-
cord-287670-z6ckhkgg	216	63	88	88	CD
cord-287670-z6ckhkgg	216	64	]	]	-RRB-
cord-287670-z6ckhkgg	216	65	.	.	.
cord-287670-z6ckhkgg	217	1	Gene	gene	NN
cord-287670-z6ckhkgg	217	2	expression	expression	NN
cord-287670-z6ckhkgg	217	3	profiling	profiling	NN
cord-287670-z6ckhkgg	217	4	has	have	VBZ
cord-287670-z6ckhkgg	217	5	identified	identify	VBN
cord-287670-z6ckhkgg	217	6	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	217	7	as	as	IN
cord-287670-z6ckhkgg	217	8	one	one	CD
cord-287670-z6ckhkgg	217	9	of	of	IN
cord-287670-z6ckhkgg	217	10	the	the	DT
cord-287670-z6ckhkgg	217	11	expressed	express	VBN
cord-287670-z6ckhkgg	217	12	genes	gene	NNS
cord-287670-z6ckhkgg	217	13	associated	associate	VBN
cord-287670-z6ckhkgg	217	14	with	with	IN
cord-287670-z6ckhkgg	217	15	the	the	DT
cord-287670-z6ckhkgg	217	16	stromal	stromal	JJ
cord-287670-z6ckhkgg	217	17	response	response	NN
cord-287670-z6ckhkgg	217	18	/	/	SYM
cord-287670-z6ckhkgg	217	19	ECM	ECM	NNP
cord-287670-z6ckhkgg	217	20	signature	signature	NN
cord-287670-z6ckhkgg	217	21	and	and	CC
cord-287670-z6ckhkgg	217	22	poor	poor	JJ
cord-287670-z6ckhkgg	217	23	prognosis	prognosis	NN
cord-287670-z6ckhkgg	217	24	in	in	IN
cord-287670-z6ckhkgg	217	25	human	human	JJ
cord-287670-z6ckhkgg	217	26	ovarian	ovarian	JJ
cord-287670-z6ckhkgg	217	27	cancer	cancer	NN
cord-287670-z6ckhkgg	217	28	[	[	-LRB-
cord-287670-z6ckhkgg	217	29	89	89	CD
cord-287670-z6ckhkgg	217	30	]	]	-RRB-
cord-287670-z6ckhkgg	217	31	.	.	.
cord-287670-z6ckhkgg	218	1	In	in	IN
cord-287670-z6ckhkgg	218	2	addition	addition	NN
cord-287670-z6ckhkgg	218	3	,	,	,
cord-287670-z6ckhkgg	218	4	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	218	5	genetic	genetic	JJ
cord-287670-z6ckhkgg	218	6	variants	variant	NNS
cord-287670-z6ckhkgg	218	7	have	have	VBP
cord-287670-z6ckhkgg	218	8	been	be	VBN
cord-287670-z6ckhkgg	218	9	associated	associate	VBN
cord-287670-z6ckhkgg	218	10	with	with	IN
cord-287670-z6ckhkgg	218	11	increased	increase	VBN
cord-287670-z6ckhkgg	218	12	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	218	13	plasma	plasma	NN
cord-287670-z6ckhkgg	218	14	levels	level	NNS
cord-287670-z6ckhkgg	218	15	and	and	CC
cord-287670-z6ckhkgg	218	16	a	a	DT
cord-287670-z6ckhkgg	218	17	risk	risk	NN
cord-287670-z6ckhkgg	218	18	of	of	IN
cord-287670-z6ckhkgg	218	19	developing	develop	VBG
cord-287670-z6ckhkgg	218	20	hepatocellular	hepatocellular	JJ
cord-287670-z6ckhkgg	218	21	carcinoma	carcinoma	NN
cord-287670-z6ckhkgg	218	22	in	in	IN
cord-287670-z6ckhkgg	218	23	hepatitis	hepatitis	NN
cord-287670-z6ckhkgg	218	24	C	C	NNP
cord-287670-z6ckhkgg	218	25	virus	virus	NN
cord-287670-z6ckhkgg	218	26	-	-	HYPH
cord-287670-z6ckhkgg	218	27	infected	infect	VBN
cord-287670-z6ckhkgg	218	28	subjects	subject	NNS
cord-287670-z6ckhkgg	218	29	[	[	-LRB-
cord-287670-z6ckhkgg	218	30	90	90	CD
cord-287670-z6ckhkgg	218	31	]	]	-RRB-
cord-287670-z6ckhkgg	218	32	.	.	.
cord-287670-z6ckhkgg	219	1	To	to	TO
cord-287670-z6ckhkgg	219	2	investigate	investigate	VB
cord-287670-z6ckhkgg	219	3	the	the	DT
cord-287670-z6ckhkgg	219	4	role	role	NN
cord-287670-z6ckhkgg	219	5	of	of	IN
cord-287670-z6ckhkgg	219	6	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	219	7	as	as	IN
cord-287670-z6ckhkgg	219	8	a	a	DT
cord-287670-z6ckhkgg	219	9	marker	marker	NN
cord-287670-z6ckhkgg	219	10	of	of	IN
cord-287670-z6ckhkgg	219	11	cancer	cancer	NN
cord-287670-z6ckhkgg	219	12	-	-	HYPH
cord-287670-z6ckhkgg	219	13	related	relate	VBN
cord-287670-z6ckhkgg	219	14	inflammation	inflammation	NN
cord-287670-z6ckhkgg	219	15	and	and	CC
cord-287670-z6ckhkgg	219	16	malignant	malignant	JJ
cord-287670-z6ckhkgg	219	17	transformation	transformation	NN
cord-287670-z6ckhkgg	219	18	and/or	and/or	CC
cord-287670-z6ckhkgg	219	19	an	an	DT
cord-287670-z6ckhkgg	219	20	active	active	JJ
cord-287670-z6ckhkgg	219	21	player	player	NN
cord-287670-z6ckhkgg	219	22	in	in	IN
cord-287670-z6ckhkgg	219	23	pathogenesis	pathogenesis	NN
cord-287670-z6ckhkgg	219	24	,	,	,
cord-287670-z6ckhkgg	219	25	our	-PRON-	PRP$
cord-287670-z6ckhkgg	219	26	group	group	NN
cord-287670-z6ckhkgg	219	27	addressed	address	VBD
cord-287670-z6ckhkgg	219	28	the	the	DT
cord-287670-z6ckhkgg	219	29	susceptibility	susceptibility	NN
cord-287670-z6ckhkgg	219	30	of	of	IN
cord-287670-z6ckhkgg	219	31	PTX3-deficient	PTX3-deficient	NNP
cord-287670-z6ckhkgg	219	32	mice	mouse	NNS
cord-287670-z6ckhkgg	219	33	to	to	IN
cord-287670-z6ckhkgg	219	34	mesenchymal	mesenchymal	JJ
cord-287670-z6ckhkgg	219	35	and	and	CC
cord-287670-z6ckhkgg	219	36	epithelial	epithelial	JJ
cord-287670-z6ckhkgg	219	37	carcinogenesis	carcinogenesis	NN
cord-287670-z6ckhkgg	219	38	in	in	IN
cord-287670-z6ckhkgg	219	39	models	model	NNS
cord-287670-z6ckhkgg	219	40	of	of	IN
cord-287670-z6ckhkgg	219	41	3-MCA	3-mca	CD
cord-287670-z6ckhkgg	219	42	-	-	HYPH
cord-287670-z6ckhkgg	219	43	induced	induce	VBN
cord-287670-z6ckhkgg	219	44	carcinogenesis	carcinogenesis	NN
cord-287670-z6ckhkgg	219	45	and	and	CC
cord-287670-z6ckhkgg	219	46	7,12-dimethylbenz	7,12-dimethylbenz	CD
cord-287670-z6ckhkgg	219	47	[	[	-LRB-
cord-287670-z6ckhkgg	219	48	/	/	SYM
cord-287670-z6ckhkgg	219	49	]	]	-RRB-
cord-287670-z6ckhkgg	219	50	anthracene	anthracene	NN
cord-287670-z6ckhkgg	219	51	/	/	SYM
cord-287670-z6ckhkgg	219	52	terephthalic	terephthalic	NN
cord-287670-z6ckhkgg	219	53	acid	acid	NN
cord-287670-z6ckhkgg	219	54	(	(	-LRB-
cord-287670-z6ckhkgg	219	55	DMBA	DMBA	NNP
cord-287670-z6ckhkgg	219	56	/	/	SYM
cord-287670-z6ckhkgg	219	57	TPA)-induced	TPA)-induced	NNP
cord-287670-z6ckhkgg	219	58	skin	skin	NN
cord-287670-z6ckhkgg	219	59	carcinogenesis	carcinogenesis	NN
cord-287670-z6ckhkgg	219	60	[	[	-LRB-
cord-287670-z6ckhkgg	219	61	12	12	CD
cord-287670-z6ckhkgg	219	62	]	]	-RRB-
cord-287670-z6ckhkgg	219	63	.	.	.
cord-287670-z6ckhkgg	220	1	In	in	IN
cord-287670-z6ckhkgg	220	2	these	these	DT
cord-287670-z6ckhkgg	220	3	models	model	NNS
cord-287670-z6ckhkgg	220	4	global	global	JJ
cord-287670-z6ckhkgg	220	5	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	220	6	deficiency	deficiency	NN
cord-287670-z6ckhkgg	220	7	was	be	VBD
cord-287670-z6ckhkgg	220	8	associated	associate	VBN
cord-287670-z6ckhkgg	220	9	with	with	IN
cord-287670-z6ckhkgg	220	10	more	more	RBR
cord-287670-z6ckhkgg	220	11	pronounced	pronounce	VBN
cord-287670-z6ckhkgg	220	12	cancer	cancer	NN
cord-287670-z6ckhkgg	220	13	-	-	HYPH
cord-287670-z6ckhkgg	220	14	related	relate	VBN
cord-287670-z6ckhkgg	220	15	inflammation	inflammation	NN
cord-287670-z6ckhkgg	220	16	relative	relative	JJ
cord-287670-z6ckhkgg	220	17	to	to	IN
cord-287670-z6ckhkgg	220	18	controls	control	NNS
cord-287670-z6ckhkgg	220	19	,	,	,
cord-287670-z6ckhkgg	220	20	displayed	display	VBD
cord-287670-z6ckhkgg	220	21	a	a	DT
cord-287670-z6ckhkgg	220	22	higher	high	JJR
cord-287670-z6ckhkgg	220	23	number	number	NN
cord-287670-z6ckhkgg	220	24	of	of	IN
cord-287670-z6ckhkgg	220	25	tumor	tumor	NN
cord-287670-z6ckhkgg	220	26	-	-	HYPH
cord-287670-z6ckhkgg	220	27	infiltrating	infiltrate	VBG
cord-287670-z6ckhkgg	220	28	macrophages	macrophage	NNS
cord-287670-z6ckhkgg	220	29	that	that	WDT
cord-287670-z6ckhkgg	220	30	showed	show	VBD
cord-287670-z6ckhkgg	220	31	upregulated	upregulated	JJ
cord-287670-z6ckhkgg	220	32	expression	expression	NN
cord-287670-z6ckhkgg	220	33	of	of	IN
cord-287670-z6ckhkgg	220	34	genes	gene	NNS
cord-287670-z6ckhkgg	220	35	associated	associate	VBN
cord-287670-z6ckhkgg	220	36	with	with	IN
cord-287670-z6ckhkgg	220	37	macrophage	macrophage	NN
cord-287670-z6ckhkgg	220	38	M2-like	M2-like	NNS
cord-287670-z6ckhkgg	220	39	polarization	polarization	NN
cord-287670-z6ckhkgg	220	40	,	,	,
cord-287670-z6ckhkgg	220	41	as	as	RB
cord-287670-z6ckhkgg	220	42	well	well	RB
cord-287670-z6ckhkgg	220	43	as	as	IN
cord-287670-z6ckhkgg	220	44	increased	increase	VBN
cord-287670-z6ckhkgg	220	45	angiogenesis	angiogenesis	NN
cord-287670-z6ckhkgg	220	46	,	,	,
cord-287670-z6ckhkgg	220	47	secretion	secretion	NN
cord-287670-z6ckhkgg	220	48	of	of	IN
cord-287670-z6ckhkgg	220	49	proinflammatory	proinflammatory	JJ
cord-287670-z6ckhkgg	220	50	cytokines	cytokine	NNS
cord-287670-z6ckhkgg	220	51	,	,	,
cord-287670-z6ckhkgg	220	52	and	and	CC
cord-287670-z6ckhkgg	220	53	complement	complement	NN
cord-287670-z6ckhkgg	220	54	activation	activation	NN
cord-287670-z6ckhkgg	220	55	(	(	-LRB-
cord-287670-z6ckhkgg	220	56	with	with	IN
cord-287670-z6ckhkgg	220	57	increased	increase	VBN
cord-287670-z6ckhkgg	220	58	C3	c3	NN
cord-287670-z6ckhkgg	220	59	and	and	CC
cord-287670-z6ckhkgg	220	60	lower	low	JJR
cord-287670-z6ckhkgg	220	61	Factor	factor	NN
cord-287670-z6ckhkgg	220	62	H	h	NN
cord-287670-z6ckhkgg	220	63	localization	localization	NN
cord-287670-z6ckhkgg	220	64	in	in	IN
cord-287670-z6ckhkgg	220	65	tumor	tumor	NN
cord-287670-z6ckhkgg	220	66	tissues	tissue	NNS
cord-287670-z6ckhkgg	220	67	in	in	IN
cord-287670-z6ckhkgg	220	68	addition	addition	NN
cord-287670-z6ckhkgg	220	69	to	to	IN
cord-287670-z6ckhkgg	220	70	higher	high	JJR
cord-287670-z6ckhkgg	220	71	C5a	C5a	NNS
cord-287670-z6ckhkgg	220	72	levels	level	NNS
cord-287670-z6ckhkgg	220	73	in	in	IN
cord-287670-z6ckhkgg	220	74	tumor	tumor	NN
cord-287670-z6ckhkgg	220	75	homogenates	homogenate	NNS
cord-287670-z6ckhkgg	220	76	)	)	-RRB-
cord-287670-z6ckhkgg	220	77	[	[	-LRB-
cord-287670-z6ckhkgg	220	78	12	12	CD
cord-287670-z6ckhkgg	220	79	]	]	-RRB-
cord-287670-z6ckhkgg	221	1	(	(	-LRB-
cord-287670-z6ckhkgg	221	2	Figure	figure	NN
cord-287670-z6ckhkgg	221	3	4	4	CD
cord-287670-z6ckhkgg	221	4	)	)	-RRB-
cord-287670-z6ckhkgg	221	5	.	.	.
cord-287670-z6ckhkgg	222	1	Moreover	moreover	RB
cord-287670-z6ckhkgg	222	2	,	,	,
cord-287670-z6ckhkgg	222	3	PTX3-deficient	ptx3-deficient	JJ
cord-287670-z6ckhkgg	222	4	tumors	tumor	NNS
cord-287670-z6ckhkgg	222	5	were	be	VBD
cord-287670-z6ckhkgg	222	6	also	also	RB
cord-287670-z6ckhkgg	222	7	characterized	characterize	VBN
cord-287670-z6ckhkgg	222	8	by	by	IN
cord-287670-z6ckhkgg	222	9	enhanced	enhanced	JJ
cord-287670-z6ckhkgg	222	10	genetic	genetic	JJ
cord-287670-z6ckhkgg	222	11	damage	damage	NN
cord-287670-z6ckhkgg	222	12	as	as	IN
cord-287670-z6ckhkgg	222	13	indicated	indicate	VBN
cord-287670-z6ckhkgg	222	14	by	by	IN
cord-287670-z6ckhkgg	222	15	increased	increase	VBN
cord-287670-z6ckhkgg	222	16	Trp53	Trp53	NNP
cord-287670-z6ckhkgg	222	17	mutations	mutation	NNS
cord-287670-z6ckhkgg	222	18	,	,	,
cord-287670-z6ckhkgg	222	19	oxidative	oxidative	JJ
cord-287670-z6ckhkgg	222	20	DNA	dna	NN
cord-287670-z6ckhkgg	222	21	damage	damage	NN
cord-287670-z6ckhkgg	222	22	,	,	,
cord-287670-z6ckhkgg	222	23	and	and	CC
cord-287670-z6ckhkgg	222	24	expression	expression	NN
cord-287670-z6ckhkgg	222	25	of	of	IN
cord-287670-z6ckhkgg	222	26	DNA	dna	NN
cord-287670-z6ckhkgg	222	27	damage	damage	NN
cord-287670-z6ckhkgg	222	28	markers	marker	NNS
cord-287670-z6ckhkgg	222	29	,	,	,
cord-287670-z6ckhkgg	222	30	in	in	IN
cord-287670-z6ckhkgg	222	31	line	line	NN
cord-287670-z6ckhkgg	222	32	with	with	IN
cord-287670-z6ckhkgg	222	33	the	the	DT
cord-287670-z6ckhkgg	222	34	hypothesis	hypothesis	NN
cord-287670-z6ckhkgg	222	35	that	that	IN
cord-287670-z6ckhkgg	222	36	inflammation	inflammation	NN
cord-287670-z6ckhkgg	222	37	contributes	contribute	VBZ
cord-287670-z6ckhkgg	222	38	to	to	IN
cord-287670-z6ckhkgg	222	39	genetic	genetic	JJ
cord-287670-z6ckhkgg	222	40	events	event	NNS
cord-287670-z6ckhkgg	222	41	that	that	WDT
cord-287670-z6ckhkgg	222	42	can	can	MD
cord-287670-z6ckhkgg	222	43	lead	lead	VB
cord-287670-z6ckhkgg	222	44	to	to	IN
cord-287670-z6ckhkgg	222	45	cancer	cancer	NN
cord-287670-z6ckhkgg	222	46	and	and	CC
cord-287670-z6ckhkgg	222	47	to	to	IN
cord-287670-z6ckhkgg	222	48	the	the	DT
cord-287670-z6ckhkgg	222	49	genetic	genetic	JJ
cord-287670-z6ckhkgg	222	50	instability	instability	NN
cord-287670-z6ckhkgg	222	51	observed	observe	VBN
cord-287670-z6ckhkgg	222	52	in	in	IN
cord-287670-z6ckhkgg	222	53	tumors	tumor	NNS
cord-287670-z6ckhkgg	222	54	[	[	-LRB-
cord-287670-z6ckhkgg	222	55	91	91	CD
cord-287670-z6ckhkgg	222	56	]	]	-RRB-
cord-287670-z6ckhkgg	222	57	.	.	.
cord-287670-z6ckhkgg	223	1	Importantly	importantly	RB
cord-287670-z6ckhkgg	223	2	,	,	,
cord-287670-z6ckhkgg	223	3	C3	c3	JJ
cord-287670-z6ckhkgg	223	4	deficiency	deficiency	NN
cord-287670-z6ckhkgg	223	5	in	in	IN
cord-287670-z6ckhkgg	223	6	mice	mice	NN
cord-287670-z6ckhkgg	223	7	or	or	CC
cord-287670-z6ckhkgg	223	8	inhibition	inhibition	NN
cord-287670-z6ckhkgg	223	9	through	through	IN
cord-287670-z6ckhkgg	223	10	a	a	DT
cord-287670-z6ckhkgg	223	11	blocking	block	VBG
cord-287670-z6ckhkgg	223	12	antibody	antibody	NN
cord-287670-z6ckhkgg	223	13	of	of	IN
cord-287670-z6ckhkgg	223	14	the	the	DT
cord-287670-z6ckhkgg	223	15	chemokine	chemokine	NN
cord-287670-z6ckhkgg	223	16	CCL2	CCL2	NNP
cord-287670-z6ckhkgg	223	17	led	lead	VBD
cord-287670-z6ckhkgg	223	18	to	to	IN
cord-287670-z6ckhkgg	223	19	a	a	DT
cord-287670-z6ckhkgg	223	20	reduction	reduction	NN
cord-287670-z6ckhkgg	223	21	in	in	IN
cord-287670-z6ckhkgg	223	22	tumor	tumor	NN
cord-287670-z6ckhkgg	223	23	macrophages	macrophage	NNS
cord-287670-z6ckhkgg	223	24	,	,	,
cord-287670-z6ckhkgg	223	25	an	an	DT
cord-287670-z6ckhkgg	223	26	outcome	outcome	NN
cord-287670-z6ckhkgg	223	27	that	that	WDT
cord-287670-z6ckhkgg	223	28	was	be	VBD
cord-287670-z6ckhkgg	223	29	sufficient	sufficient	JJ
cord-287670-z6ckhkgg	223	30	to	to	TO
cord-287670-z6ckhkgg	223	31	revert	revert	VB
cord-287670-z6ckhkgg	223	32	the	the	DT
cord-287670-z6ckhkgg	223	33	increased	increase	VBN
cord-287670-z6ckhkgg	223	34	susceptibility	susceptibility	NN
cord-287670-z6ckhkgg	223	35	to	to	TO
cord-287670-z6ckhkgg	223	36	chemically	chemically	RB
cord-287670-z6ckhkgg	223	37	induced	induce	VBN
cord-287670-z6ckhkgg	223	38	carcinogenesis	carcinogenesis	NN
cord-287670-z6ckhkgg	223	39	of	of	IN
cord-287670-z6ckhkgg	223	40	PTX3-deficient	PTX3-deficient	NNP
cord-287670-z6ckhkgg	223	41	mice	mouse	NNS
cord-287670-z6ckhkgg	223	42	.	.	.
cord-287670-z6ckhkgg	224	1	These	these	DT
cord-287670-z6ckhkgg	224	2	results	result	NNS
cord-287670-z6ckhkgg	224	3	indicate	indicate	VBP
cord-287670-z6ckhkgg	224	4	that	that	IN
cord-287670-z6ckhkgg	224	5	,	,	,
cord-287670-z6ckhkgg	224	6	at	at	IN
cord-287670-z6ckhkgg	224	7	least	least	JJS
cord-287670-z6ckhkgg	224	8	in	in	IN
cord-287670-z6ckhkgg	224	9	mice	mouse	NNS
cord-287670-z6ckhkgg	224	10	,	,	,
cord-287670-z6ckhkgg	224	11	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	224	12	exerts	exert	VBZ
cord-287670-z6ckhkgg	224	13	a	a	DT
cord-287670-z6ckhkgg	224	14	protective	protective	JJ
cord-287670-z6ckhkgg	224	15	role	role	NN
cord-287670-z6ckhkgg	224	16	in	in	IN
cord-287670-z6ckhkgg	224	17	carcinogenesis	carcinogenesis	NN
cord-287670-z6ckhkgg	224	18	and	and	CC
cord-287670-z6ckhkgg	224	19	that	that	IN
cord-287670-z6ckhkgg	224	20	this	this	DT
cord-287670-z6ckhkgg	224	21	effect	effect	NN
cord-287670-z6ckhkgg	224	22	is	be	VBZ
cord-287670-z6ckhkgg	224	23	based	base	VBN
cord-287670-z6ckhkgg	224	24	on	on	IN
cord-287670-z6ckhkgg	224	25	the	the	DT
cord-287670-z6ckhkgg	224	26	regulation	regulation	NN
cord-287670-z6ckhkgg	224	27	of	of	IN
cord-287670-z6ckhkgg	224	28	complement	complement	JJ
cord-287670-z6ckhkgg	224	29	activation	activation	NN
cord-287670-z6ckhkgg	224	30	[	[	-LRB-
cord-287670-z6ckhkgg	224	31	12	12	CD
cord-287670-z6ckhkgg	224	32	]	]	-RRB-
cord-287670-z6ckhkgg	224	33	(	(	-LRB-
cord-287670-z6ckhkgg	224	34	Figure	figure	NN
cord-287670-z6ckhkgg	224	35	3	3	CD
cord-287670-z6ckhkgg	224	36	)	)	-RRB-
cord-287670-z6ckhkgg	224	37	.	.	.
cord-287670-z6ckhkgg	225	1	The	the	DT
cord-287670-z6ckhkgg	225	2	potential	potential	JJ
cord-287670-z6ckhkgg	225	3	protumoral	protumoral	JJ
cord-287670-z6ckhkgg	225	4	role	role	NN
cord-287670-z6ckhkgg	225	5	of	of	IN
cord-287670-z6ckhkgg	225	6	the	the	DT
cord-287670-z6ckhkgg	225	7	complement	complement	NN
cord-287670-z6ckhkgg	225	8	system	system	NN
cord-287670-z6ckhkgg	225	9	has	have	VBZ
cord-287670-z6ckhkgg	225	10	also	also	RB
cord-287670-z6ckhkgg	225	11	been	be	VBN
cord-287670-z6ckhkgg	225	12	suggested	suggest	VBN
cord-287670-z6ckhkgg	225	13	by	by	IN
cord-287670-z6ckhkgg	225	14	a	a	DT
cord-287670-z6ckhkgg	225	15	recent	recent	JJ
cord-287670-z6ckhkgg	225	16	study	study	NN
cord-287670-z6ckhkgg	225	17	showing	show	VBG
cord-287670-z6ckhkgg	225	18	that	that	DT
cord-287670-z6ckhkgg	225	19	deficiency	deficiency	NN
cord-287670-z6ckhkgg	225	20	in	in	IN
cord-287670-z6ckhkgg	225	21	key	key	JJ
cord-287670-z6ckhkgg	225	22	components	component	NNS
cord-287670-z6ckhkgg	225	23	of	of	IN
cord-287670-z6ckhkgg	225	24	the	the	DT
cord-287670-z6ckhkgg	225	25	complement	complement	JJ
cord-287670-z6ckhkgg	225	26	pathway	pathway	NN
cord-287670-z6ckhkgg	225	27	(	(	-LRB-
cord-287670-z6ckhkgg	225	28	e.g.	e.g.	RB
cord-287670-z6ckhkgg	225	29	,	,	,
cord-287670-z6ckhkgg	225	30	C3	C3	NNP
cord-287670-z6ckhkgg	225	31	,	,	,
cord-287670-z6ckhkgg	225	32	C5	C5	NNP
cord-287670-z6ckhkgg	225	33	,	,	,
cord-287670-z6ckhkgg	225	34	C5a	C5a	NNP
cord-287670-z6ckhkgg	225	35	receptor	receptor	NN
cord-287670-z6ckhkgg	225	36	)	)	-RRB-
cord-287670-z6ckhkgg	225	37	can	can	MD
cord-287670-z6ckhkgg	225	38	be	be	VB
cord-287670-z6ckhkgg	225	39	linked	link	VBN
cord-287670-z6ckhkgg	225	40	to	to	IN
cord-287670-z6ckhkgg	225	41	colitis	colitis	NN
cord-287670-z6ckhkgg	225	42	-	-	HYPH
cord-287670-z6ckhkgg	225	43	associated	associate	VBN
cord-287670-z6ckhkgg	225	44	colon	colon	NN
cord-287670-z6ckhkgg	225	45	cancer	cancer	NN
cord-287670-z6ckhkgg	225	46	resistance	resistance	NN
cord-287670-z6ckhkgg	225	47	in	in	IN
cord-287670-z6ckhkgg	225	48	mice	mouse	NNS
cord-287670-z6ckhkgg	225	49	[	[	-LRB-
cord-287670-z6ckhkgg	225	50	92	92	CD
cord-287670-z6ckhkgg	225	51	]	]	-RRB-
cord-287670-z6ckhkgg	225	52	.	.	.
cord-287670-z6ckhkgg	226	1	However	however	RB
cord-287670-z6ckhkgg	226	2	,	,	,
cord-287670-z6ckhkgg	226	3	in	in	IN
cord-287670-z6ckhkgg	226	4	specific	specific	JJ
cord-287670-z6ckhkgg	226	5	mouse	mouse	NN
cord-287670-z6ckhkgg	226	6	models	model	NNS
cord-287670-z6ckhkgg	226	7	,	,	,
cord-287670-z6ckhkgg	226	8	cancer	cancer	NN
cord-287670-z6ckhkgg	226	9	-	-	HYPH
cord-287670-z6ckhkgg	226	10	related	relate	VBN
cord-287670-z6ckhkgg	226	11	inflammation	inflammation	NN
cord-287670-z6ckhkgg	226	12	was	be	VBD
cord-287670-z6ckhkgg	226	13	found	find	VBN
cord-287670-z6ckhkgg	226	14	to	to	TO
cord-287670-z6ckhkgg	226	15	be	be	VB
cord-287670-z6ckhkgg	226	16	complement	complement	JJ
cord-287670-z6ckhkgg	226	17	independent	independent	JJ
cord-287670-z6ckhkgg	226	18	[	[	-LRB-
cord-287670-z6ckhkgg	226	19	93	93	CD
cord-287670-z6ckhkgg	226	20	,	,	,
cord-287670-z6ckhkgg	226	21	94	94	CD
cord-287670-z6ckhkgg	226	22	]	]	-RRB-
cord-287670-z6ckhkgg	226	23	,	,	,
cord-287670-z6ckhkgg	226	24	indicating	indicate	VBG
cord-287670-z6ckhkgg	226	25	that	that	IN
cord-287670-z6ckhkgg	226	26	complement	complement	NN
cord-287670-z6ckhkgg	226	27	activation	activation	NN
cord-287670-z6ckhkgg	226	28	may	may	MD
cord-287670-z6ckhkgg	226	29	contribute	contribute	VB
cord-287670-z6ckhkgg	226	30	to	to	IN
cord-287670-z6ckhkgg	226	31	cancer	cancer	NN
cord-287670-z6ckhkgg	226	32	-	-	HYPH
cord-287670-z6ckhkgg	226	33	related	relate	VBN
cord-287670-z6ckhkgg	226	34	inflammation	inflammation	NN
cord-287670-z6ckhkgg	226	35	depending	depend	VBG
cord-287670-z6ckhkgg	226	36	on	on	IN
cord-287670-z6ckhkgg	226	37	the	the	DT
cord-287670-z6ckhkgg	226	38	tissue	tissue	NN
cord-287670-z6ckhkgg	226	39	context	context	NN
cord-287670-z6ckhkgg	226	40	and	and	CC
cord-287670-z6ckhkgg	226	41	driving	drive	VBG
cord-287670-z6ckhkgg	226	42	molecular	molecular	JJ
cord-287670-z6ckhkgg	226	43	pathways	pathway	NNS
cord-287670-z6ckhkgg	226	44	.	.	.
cord-287670-z6ckhkgg	227	1	The	the	DT
cord-287670-z6ckhkgg	227	2	functional	functional	JJ
cord-287670-z6ckhkgg	227	3	relevance	relevance	NN
cord-287670-z6ckhkgg	227	4	of	of	IN
cord-287670-z6ckhkgg	227	5	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	227	6	in	in	IN
cord-287670-z6ckhkgg	227	7	human	human	JJ
cord-287670-z6ckhkgg	227	8	cancer	cancer	NN
cord-287670-z6ckhkgg	227	9	has	have	VBZ
cord-287670-z6ckhkgg	227	10	been	be	VBN
cord-287670-z6ckhkgg	227	11	further	further	RB
cord-287670-z6ckhkgg	227	12	strengthened	strengthen	VBN
cord-287670-z6ckhkgg	227	13	by	by	IN
cord-287670-z6ckhkgg	227	14	results	result	NNS
cord-287670-z6ckhkgg	227	15	showing	show	VBG
cord-287670-z6ckhkgg	227	16	that	that	IN
cord-287670-z6ckhkgg	227	17	the	the	DT
cord-287670-z6ckhkgg	227	18	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	227	19	promoter	promoter	NN
cord-287670-z6ckhkgg	227	20	and	and	CC
cord-287670-z6ckhkgg	227	21	regulatory	regulatory	JJ
cord-287670-z6ckhkgg	227	22	regions	region	NNS
cord-287670-z6ckhkgg	227	23	of	of	IN
cord-287670-z6ckhkgg	227	24	the	the	DT
cord-287670-z6ckhkgg	227	25	locus	locus	NN
cord-287670-z6ckhkgg	227	26	are	be	VBP
cord-287670-z6ckhkgg	227	27	highly	highly	RB
cord-287670-z6ckhkgg	227	28	methylated	methylate	VBN
cord-287670-z6ckhkgg	227	29	in	in	IN
cord-287670-z6ckhkgg	227	30	human	human	JJ
cord-287670-z6ckhkgg	227	31	mesenchymal	mesenchymal	JJ
cord-287670-z6ckhkgg	227	32	and	and	CC
cord-287670-z6ckhkgg	227	33	epithelial	epithelial	JJ
cord-287670-z6ckhkgg	227	34	tumors	tumor	NNS
cord-287670-z6ckhkgg	227	35	,	,	,
cord-287670-z6ckhkgg	227	36	in	in	IN
cord-287670-z6ckhkgg	227	37	contrast	contrast	NN
cord-287670-z6ckhkgg	227	38	to	to	IN
cord-287670-z6ckhkgg	227	39	normal	normal	JJ
cord-287670-z6ckhkgg	227	40	healthy	healthy	JJ
cord-287670-z6ckhkgg	227	41	tissue	tissue	NN
cord-287670-z6ckhkgg	227	42	,	,	,
cord-287670-z6ckhkgg	227	43	and	and	CC
cord-287670-z6ckhkgg	227	44	,	,	,
cord-287670-z6ckhkgg	227	45	furthermore	furthermore	RB
cord-287670-z6ckhkgg	227	46	,	,	,
cord-287670-z6ckhkgg	227	47	that	that	IN
cord-287670-z6ckhkgg	227	48	such	such	JJ
cord-287670-z6ckhkgg	227	49	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	227	50	methylation	methylation	NN
cord-287670-z6ckhkgg	227	51	can	can	MD
cord-287670-z6ckhkgg	227	52	result	result	VB
cord-287670-z6ckhkgg	227	53	in	in	IN
cord-287670-z6ckhkgg	227	54	silencing	silencing	NN
cord-287670-z6ckhkgg	227	55	of	of	IN
cord-287670-z6ckhkgg	227	56	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	227	57	protein	protein	NN
cord-287670-z6ckhkgg	227	58	expression	expression	NN
cord-287670-z6ckhkgg	227	59	[	[	-LRB-
cord-287670-z6ckhkgg	227	60	12	12	CD
cord-287670-z6ckhkgg	227	61	]	]	-RRB-
cord-287670-z6ckhkgg	227	62	.	.	.
cord-287670-z6ckhkgg	228	1	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	228	2	promoter	promoter	NN
cord-287670-z6ckhkgg	228	3	hypermethylation	hypermethylation	NN
cord-287670-z6ckhkgg	228	4	and	and	CC
cord-287670-z6ckhkgg	228	5	reduced	reduce	VBD
cord-287670-z6ckhkgg	228	6	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	228	7	expression	expression	NN
cord-287670-z6ckhkgg	228	8	have	have	VBP
cord-287670-z6ckhkgg	228	9	also	also	RB
cord-287670-z6ckhkgg	228	10	been	be	VBN
cord-287670-z6ckhkgg	228	11	reported	report	VBN
cord-287670-z6ckhkgg	228	12	in	in	IN
cord-287670-z6ckhkgg	228	13	human	human	JJ
cord-287670-z6ckhkgg	228	14	esophageal	esophageal	JJ
cord-287670-z6ckhkgg	228	15	squamous	squamous	JJ
cord-287670-z6ckhkgg	228	16	cell	cell	NN
cord-287670-z6ckhkgg	228	17	carcinomas	carcinoma	NNS
cord-287670-z6ckhkgg	228	18	[	[	-LRB-
cord-287670-z6ckhkgg	228	19	95	95	CD
cord-287670-z6ckhkgg	228	20	]	]	-RRB-
cord-287670-z6ckhkgg	228	21	.	.	.
cord-287670-z6ckhkgg	229	1	Taken	take	VBN
cord-287670-z6ckhkgg	229	2	together	together	RB
cord-287670-z6ckhkgg	229	3	,	,	,
cord-287670-z6ckhkgg	229	4	these	these	DT
cord-287670-z6ckhkgg	229	5	studies	study	NNS
cord-287670-z6ckhkgg	229	6	indicate	indicate	VBP
cord-287670-z6ckhkgg	229	7	that	that	IN
cord-287670-z6ckhkgg	229	8	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	229	9	,	,	,
cord-287670-z6ckhkgg	229	10	which	which	WDT
cord-287670-z6ckhkgg	229	11	is	be	VBZ
cord-287670-z6ckhkgg	229	12	an	an	DT
cord-287670-z6ckhkgg	229	13	essential	essential	JJ
cord-287670-z6ckhkgg	229	14	component	component	NN
cord-287670-z6ckhkgg	229	15	of	of	IN
cord-287670-z6ckhkgg	229	16	humoral	humoral	JJ
cord-287670-z6ckhkgg	229	17	innate	innate	JJ
cord-287670-z6ckhkgg	229	18	immunity	immunity	NN
cord-287670-z6ckhkgg	229	19	and	and	CC
cord-287670-z6ckhkgg	229	20	a	a	DT
cord-287670-z6ckhkgg	229	21	regulator	regulator	NN
cord-287670-z6ckhkgg	229	22	of	of	IN
cord-287670-z6ckhkgg	229	23	complement	complement	JJ
cord-287670-z6ckhkgg	229	24	activation	activation	NN
cord-287670-z6ckhkgg	229	25	,	,	,
cord-287670-z6ckhkgg	229	26	also	also	RB
cord-287670-z6ckhkgg	229	27	acts	act	VBZ
cord-287670-z6ckhkgg	229	28	as	as	IN
cord-287670-z6ckhkgg	229	29	an	an	DT
cord-287670-z6ckhkgg	229	30	extrinsic	extrinsic	JJ
cord-287670-z6ckhkgg	229	31	oncosuppressor	oncosuppressor	NN
cord-287670-z6ckhkgg	229	32	gene	gene	NN
cord-287670-z6ckhkgg	229	33	in	in	IN
cord-287670-z6ckhkgg	229	34	mouse	mouse	NN
cord-287670-z6ckhkgg	229	35	and	and	CC
cord-287670-z6ckhkgg	229	36	man	man	NN
cord-287670-z6ckhkgg	229	37	.	.	.
cord-287670-z6ckhkgg	230	1	Moreover	moreover	RB
cord-287670-z6ckhkgg	230	2	,	,	,
cord-287670-z6ckhkgg	230	3	its	-PRON-	PRP$
cord-287670-z6ckhkgg	230	4	oncosuppressive	oncosuppressive	JJ
cord-287670-z6ckhkgg	230	5	role	role	NN
cord-287670-z6ckhkgg	230	6	appears	appear	VBZ
cord-287670-z6ckhkgg	230	7	to	to	TO
cord-287670-z6ckhkgg	230	8	act	act	VB
cord-287670-z6ckhkgg	230	9	at	at	IN
cord-287670-z6ckhkgg	230	10	the	the	DT
cord-287670-z6ckhkgg	230	11	level	level	NN
cord-287670-z6ckhkgg	230	12	of	of	IN
cord-287670-z6ckhkgg	230	13	complement	complement	NN
cord-287670-z6ckhkgg	230	14	-	-	HYPH
cord-287670-z6ckhkgg	230	15	mediated	mediate	VBN
cord-287670-z6ckhkgg	230	16	,	,	,
cord-287670-z6ckhkgg	230	17	macrophagesustained	macrophagesustaine	VBN
cord-287670-z6ckhkgg	230	18	,	,	,
cord-287670-z6ckhkgg	230	19	tumor	tumor	NN
cord-287670-z6ckhkgg	230	20	-	-	HYPH
cord-287670-z6ckhkgg	230	21	promoting	promote	VBG
cord-287670-z6ckhkgg	230	22	inflammation	inflammation	NN
cord-287670-z6ckhkgg	230	23	inhibition	inhibition	NN
cord-287670-z6ckhkgg	230	24	[	[	-LRB-
cord-287670-z6ckhkgg	230	25	95	95	CD
cord-287670-z6ckhkgg	230	26	]	]	-RRB-
cord-287670-z6ckhkgg	230	27	.	.	.
cord-287670-z6ckhkgg	231	1	Of	of	IN
cord-287670-z6ckhkgg	231	2	note	note	NN
cord-287670-z6ckhkgg	231	3	,	,	,
cord-287670-z6ckhkgg	231	4	since	since	IN
cord-287670-z6ckhkgg	231	5	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	231	6	binds	bind	VBZ
cord-287670-z6ckhkgg	231	7	certain	certain	JJ
cord-287670-z6ckhkgg	231	8	FGFs	fgf	NNS
cord-287670-z6ckhkgg	231	9	(	(	-LRB-
cord-287670-z6ckhkgg	231	10	i.e.	i.e.	FW
cord-287670-z6ckhkgg	231	11	,	,	,
cord-287670-z6ckhkgg	231	12	FGF2	FGF2	NNP
cord-287670-z6ckhkgg	231	13	,	,	,
cord-287670-z6ckhkgg	231	14	FGF8	FGF8	NNP
cord-287670-z6ckhkgg	231	15	)	)	-RRB-
cord-287670-z6ckhkgg	231	16	,	,	,
cord-287670-z6ckhkgg	231	17	impairing	impair	VBG
cord-287670-z6ckhkgg	231	18	the	the	DT
cord-287670-z6ckhkgg	231	19	interaction	interaction	NN
cord-287670-z6ckhkgg	231	20	with	with	IN
cord-287670-z6ckhkgg	231	21	their	-PRON-	PRP$
cord-287670-z6ckhkgg	231	22	cognate	cognate	JJ
cord-287670-z6ckhkgg	231	23	receptors	receptor	NNS
cord-287670-z6ckhkgg	231	24	[	[	-LRB-
cord-287670-z6ckhkgg	231	25	60	60	CD
cord-287670-z6ckhkgg	231	26	,	,	,
cord-287670-z6ckhkgg	231	27	61	61	CD
cord-287670-z6ckhkgg	231	28	]	]	-RRB-
cord-287670-z6ckhkgg	231	29	,	,	,
cord-287670-z6ckhkgg	231	30	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	231	31	plays	play	VBZ
cord-287670-z6ckhkgg	231	32	a	a	DT
cord-287670-z6ckhkgg	231	33	protective	protective	JJ
cord-287670-z6ckhkgg	231	34	role	role	NN
cord-287670-z6ckhkgg	231	35	in	in	IN
cord-287670-z6ckhkgg	231	36	inhibiting	inhibit	VBG
cord-287670-z6ckhkgg	231	37	tumor	tumor	NN
cord-287670-z6ckhkgg	231	38	growth	growth	NN
cord-287670-z6ckhkgg	231	39	by	by	IN
cord-287670-z6ckhkgg	231	40	regulating	regulate	VBG
cord-287670-z6ckhkgg	231	41	FGF	FGF	NNP
cord-287670-z6ckhkgg	231	42	-	-	HYPH
cord-287670-z6ckhkgg	231	43	dependent	dependent	JJ
cord-287670-z6ckhkgg	231	44	effects	effect	NNS
cord-287670-z6ckhkgg	231	45	as	as	RB
cord-287670-z6ckhkgg	231	46	well	well	RB
cord-287670-z6ckhkgg	231	47	[	[	-LRB-
cord-287670-z6ckhkgg	231	48	60	60	CD
cord-287670-z6ckhkgg	231	49	,	,	,
cord-287670-z6ckhkgg	231	50	96	96	CD
cord-287670-z6ckhkgg	231	51	]	]	-RRB-
cord-287670-z6ckhkgg	232	1	(	(	-LRB-
cord-287670-z6ckhkgg	232	2	Figure	figure	NN
cord-287670-z6ckhkgg	232	3	4	4	CD
cord-287670-z6ckhkgg	232	4	)	)	-RRB-
cord-287670-z6ckhkgg	232	5	.	.	.
cord-287670-z6ckhkgg	233	1	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	233	2	overexpression	overexpression	NN
cord-287670-z6ckhkgg	233	3	,	,	,
cord-287670-z6ckhkgg	233	4	under	under	IN
cord-287670-z6ckhkgg	233	5	the	the	DT
cord-287670-z6ckhkgg	233	6	control	control	NN
cord-287670-z6ckhkgg	233	7	of	of	IN
cord-287670-z6ckhkgg	233	8	the	the	DT
cord-287670-z6ckhkgg	233	9	endothelium	endothelium	NN
cord-287670-z6ckhkgg	233	10	-	-	HYPH
cord-287670-z6ckhkgg	233	11	specific	specific	JJ
cord-287670-z6ckhkgg	233	12	Tie2	Tie2	NNP
cord-287670-z6ckhkgg	233	13	/	/	SYM
cord-287670-z6ckhkgg	233	14	Tek	Tek	NNP
cord-287670-z6ckhkgg	233	15	transcription	transcription	NN
cord-287670-z6ckhkgg	233	16	regulatory	regulatory	JJ
cord-287670-z6ckhkgg	233	17	sequences	sequence	NNS
cord-287670-z6ckhkgg	233	18	,	,	,
cord-287670-z6ckhkgg	233	19	has	have	VBZ
cord-287670-z6ckhkgg	233	20	been	be	VBN
cord-287670-z6ckhkgg	233	21	associated	associate	VBN
cord-287670-z6ckhkgg	233	22	with	with	IN
cord-287670-z6ckhkgg	233	23	reduced	reduce	VBN
cord-287670-z6ckhkgg	233	24	malignant	malignant	JJ
cord-287670-z6ckhkgg	233	25	growth	growth	NN
cord-287670-z6ckhkgg	233	26	of	of	IN
cord-287670-z6ckhkgg	233	27	FGF2-dependent	FGF2-dependent	NNP
cord-287670-z6ckhkgg	233	28	mouse	mouse	NN
cord-287670-z6ckhkgg	233	29	TRAMP	tramp	NN
cord-287670-z6ckhkgg	233	30	-	-	HYPH
cord-287670-z6ckhkgg	233	31	C2	C2	NNP
cord-287670-z6ckhkgg	233	32	prostate	prostate	NN
cord-287670-z6ckhkgg	233	33	cancer	cancer	NN
cord-287670-z6ckhkgg	233	34	and	and	CC
cord-287670-z6ckhkgg	233	35	B16	B16	NNP
cord-287670-z6ckhkgg	233	36	melanoma	melanoma	NN
cord-287670-z6ckhkgg	233	37	as	as	RB
cord-287670-z6ckhkgg	233	38	well	well	RB
cord-287670-z6ckhkgg	233	39	as	as	IN
cord-287670-z6ckhkgg	233	40	reduced	reduce	VBN
cord-287670-z6ckhkgg	233	41	melanoma	melanoma	NN
cord-287670-z6ckhkgg	233	42	metastasis	metastasis	NN
cord-287670-z6ckhkgg	233	43	and	and	CC
cord-287670-z6ckhkgg	233	44	cancer	cancer	NN
cord-287670-z6ckhkgg	233	45	-	-	HYPH
cord-287670-z6ckhkgg	233	46	associated	associate	VBN
cord-287670-z6ckhkgg	233	47	angiogenesis	angiogenesis	NN
cord-287670-z6ckhkgg	233	48	[	[	-LRB-
cord-287670-z6ckhkgg	233	49	96	96	CD
cord-287670-z6ckhkgg	233	50	]	]	-RRB-
cord-287670-z6ckhkgg	233	51	.	.	.
cord-287670-z6ckhkgg	234	1	Furthermore	furthermore	RB
cord-287670-z6ckhkgg	234	2	,	,	,
cord-287670-z6ckhkgg	234	3	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	234	4	has	have	VBZ
cord-287670-z6ckhkgg	234	5	also	also	RB
cord-287670-z6ckhkgg	234	6	been	be	VBN
cord-287670-z6ckhkgg	234	7	shown	show	VBN
cord-287670-z6ckhkgg	234	8	to	to	TO
cord-287670-z6ckhkgg	234	9	impair	impair	VB
cord-287670-z6ckhkgg	234	10	cell	cell	NN
cord-287670-z6ckhkgg	234	11	proliferation	proliferation	NN
cord-287670-z6ckhkgg	234	12	and	and	CC
cord-287670-z6ckhkgg	234	13	epithelial	epithelial	NN
cord-287670-z6ckhkgg	234	14	-	-	HYPH
cord-287670-z6ckhkgg	234	15	mesenchymal	mesenchymal	JJ
cord-287670-z6ckhkgg	234	16	transition	transition	NN
cord-287670-z6ckhkgg	234	17	(	(	-LRB-
cord-287670-z6ckhkgg	234	18	EMT	EMT	NNP
cord-287670-z6ckhkgg	234	19	)	)	-RRB-
cord-287670-z6ckhkgg	234	20	in	in	IN
cord-287670-z6ckhkgg	234	21	human	human	JJ
cord-287670-z6ckhkgg	234	22	melanoma	melanoma	NN
cord-287670-z6ckhkgg	234	23	cells	cell	NNS
cord-287670-z6ckhkgg	234	24	in	in	IN
cord-287670-z6ckhkgg	234	25	vitro	vitro	FW
cord-287670-z6ckhkgg	234	26	[	[	-LRB-
cord-287670-z6ckhkgg	234	27	60	60	CD
cord-287670-z6ckhkgg	234	28	]	]	-RRB-
cord-287670-z6ckhkgg	234	29	.	.	.
cord-287670-z6ckhkgg	235	1	However	however	RB
cord-287670-z6ckhkgg	235	2	,	,	,
cord-287670-z6ckhkgg	235	3	contrary	contrary	JJ
cord-287670-z6ckhkgg	235	4	to	to	IN
cord-287670-z6ckhkgg	235	5	the	the	DT
cord-287670-z6ckhkgg	235	6	reports	report	NNS
cord-287670-z6ckhkgg	235	7	describing	describe	VBG
cord-287670-z6ckhkgg	235	8	a	a	DT
cord-287670-z6ckhkgg	235	9	protective	protective	JJ
cord-287670-z6ckhkgg	235	10	role	role	NN
cord-287670-z6ckhkgg	235	11	of	of	IN
cord-287670-z6ckhkgg	235	12	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	235	13	against	against	IN
cord-287670-z6ckhkgg	235	14	cancer	cancer	NN
cord-287670-z6ckhkgg	235	15	,	,	,
cord-287670-z6ckhkgg	235	16	other	other	JJ
cord-287670-z6ckhkgg	235	17	studies	study	NNS
cord-287670-z6ckhkgg	235	18	have	have	VBP
cord-287670-z6ckhkgg	235	19	suggested	suggest	VBN
cord-287670-z6ckhkgg	235	20	a	a	DT
cord-287670-z6ckhkgg	235	21	protumorigenic	protumorigenic	JJ
cord-287670-z6ckhkgg	235	22	effect	effect	NN
cord-287670-z6ckhkgg	235	23	(	(	-LRB-
cord-287670-z6ckhkgg	235	24	Figure	figure	NN
cord-287670-z6ckhkgg	235	25	3	3	CD
cord-287670-z6ckhkgg	235	26	)	)	-RRB-
cord-287670-z6ckhkgg	235	27	.	.	.
cord-287670-z6ckhkgg	236	1	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	236	2	has	have	VBZ
cord-287670-z6ckhkgg	236	3	been	be	VBN
cord-287670-z6ckhkgg	236	4	reported	report	VBN
cord-287670-z6ckhkgg	236	5	to	to	TO
cord-287670-z6ckhkgg	236	6	promote	promote	VB
cord-287670-z6ckhkgg	236	7	in	in	IN
cord-287670-z6ckhkgg	236	8	vitro	vitro	FW
cord-287670-z6ckhkgg	236	9	migration	migration	NN
cord-287670-z6ckhkgg	236	10	and	and	CC
cord-287670-z6ckhkgg	236	11	invasion	invasion	NN
cord-287670-z6ckhkgg	236	12	of	of	IN
cord-287670-z6ckhkgg	236	13	human	human	JJ
cord-287670-z6ckhkgg	236	14	pancreatic	pancreatic	NN
cord-287670-z6ckhkgg	236	15	tumor	tumor	NN
cord-287670-z6ckhkgg	236	16	cells	cell	NNS
cord-287670-z6ckhkgg	236	17	,	,	,
cord-287670-z6ckhkgg	236	18	breast	breast	NN
cord-287670-z6ckhkgg	236	19	carcinoma	carcinoma	NN
cord-287670-z6ckhkgg	236	20	,	,	,
cord-287670-z6ckhkgg	236	21	and	and	CC
cord-287670-z6ckhkgg	236	22	head	head	NN
cord-287670-z6ckhkgg	236	23	and	and	CC
cord-287670-z6ckhkgg	236	24	neck	neck	NN
cord-287670-z6ckhkgg	236	25	squamous	squamous	JJ
cord-287670-z6ckhkgg	236	26	cell	cell	NN
cord-287670-z6ckhkgg	236	27	carcinoma	carcinoma	NN
cord-287670-z6ckhkgg	236	28	,	,	,
cord-287670-z6ckhkgg	236	29	as	as	RB
cord-287670-z6ckhkgg	236	30	well	well	RB
cord-287670-z6ckhkgg	236	31	as	as	IN
cord-287670-z6ckhkgg	236	32	macrophage	macrophage	NN
cord-287670-z6ckhkgg	236	33	chemotaxis	chemotaxis	NN
cord-287670-z6ckhkgg	236	34	,	,	,
cord-287670-z6ckhkgg	236	35	by	by	IN
cord-287670-z6ckhkgg	236	36	still	still	RB
cord-287670-z6ckhkgg	236	37	poorly	poorly	RB
cord-287670-z6ckhkgg	236	38	defined	define	VBN
cord-287670-z6ckhkgg	236	39	molecular	molecular	JJ
cord-287670-z6ckhkgg	236	40	mechanisms	mechanism	NNS
cord-287670-z6ckhkgg	236	41	[	[	-LRB-
cord-287670-z6ckhkgg	236	42	82	82	CD
cord-287670-z6ckhkgg	236	43	,	,	,
cord-287670-z6ckhkgg	236	44	84	84	CD
cord-287670-z6ckhkgg	236	45	,	,	,
cord-287670-z6ckhkgg	236	46	97	97	CD
cord-287670-z6ckhkgg	236	47	,	,	,
cord-287670-z6ckhkgg	236	48	98	98	CD
cord-287670-z6ckhkgg	236	49	]	]	-RRB-
cord-287670-z6ckhkgg	236	50	.	.	.
cord-287670-z6ckhkgg	237	1	In	in	IN
cord-287670-z6ckhkgg	237	2	another	another	DT
cord-287670-z6ckhkgg	237	3	study	study	NN
cord-287670-z6ckhkgg	237	4	,	,	,
cord-287670-z6ckhkgg	237	5	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	237	6	silencing	silencing	NN
cord-287670-z6ckhkgg	237	7	was	be	VBD
cord-287670-z6ckhkgg	237	8	found	find	VBN
cord-287670-z6ckhkgg	237	9	to	to	TO
cord-287670-z6ckhkgg	237	10	promote	promote	VB
cord-287670-z6ckhkgg	237	11	the	the	DT
cord-287670-z6ckhkgg	237	12	gastric	gastric	JJ
cord-287670-z6ckhkgg	237	13	cancer	cancer	NN
cord-287670-z6ckhkgg	237	14	cell	cell	NN
cord-287670-z6ckhkgg	237	15	migratory	migratory	JJ
cord-287670-z6ckhkgg	237	16	potential	potential	NN
cord-287670-z6ckhkgg	237	17	,	,	,
cord-287670-z6ckhkgg	237	18	the	the	DT
cord-287670-z6ckhkgg	237	19	recruitment	recruitment	NN
cord-287670-z6ckhkgg	237	20	of	of	IN
cord-287670-z6ckhkgg	237	21	macrophages	macrophage	NNS
cord-287670-z6ckhkgg	237	22	,	,	,
cord-287670-z6ckhkgg	237	23	and	and	CC
cord-287670-z6ckhkgg	237	24	their	-PRON-	PRP$
cord-287670-z6ckhkgg	237	25	subsequent	subsequent	JJ
cord-287670-z6ckhkgg	237	26	binding	binding	NN
cord-287670-z6ckhkgg	237	27	to	to	IN
cord-287670-z6ckhkgg	237	28	gastric	gastric	JJ
cord-287670-z6ckhkgg	237	29	cancer	cancer	NN
cord-287670-z6ckhkgg	237	30	cells	cell	NNS
cord-287670-z6ckhkgg	237	31	[	[	-LRB-
cord-287670-z6ckhkgg	237	32	98	98	CD
cord-287670-z6ckhkgg	237	33	]	]	-RRB-
cord-287670-z6ckhkgg	237	34	.	.	.
cord-287670-z6ckhkgg	238	1	In	in	IN
cord-287670-z6ckhkgg	238	2	addition	addition	NN
cord-287670-z6ckhkgg	238	3	,	,	,
cord-287670-z6ckhkgg	238	4	the	the	DT
cord-287670-z6ckhkgg	238	5	transcription	transcription	NN
cord-287670-z6ckhkgg	238	6	factor	factor	NN
cord-287670-z6ckhkgg	238	7	CCAAT	CCAAT	NNP
cord-287670-z6ckhkgg	238	8	/	/	SYM
cord-287670-z6ckhkgg	238	9	enhancerbinding	enhancerbinde	VBG
cord-287670-z6ckhkgg	238	10	protein	protein	NN
cord-287670-z6ckhkgg	238	11	delta	delta	NN
cord-287670-z6ckhkgg	238	12	(	(	-LRB-
cord-287670-z6ckhkgg	238	13	CEBPD	CEBPD	NNP
cord-287670-z6ckhkgg	238	14	)	)	-RRB-
cord-287670-z6ckhkgg	238	15	was	be	VBD
cord-287670-z6ckhkgg	238	16	shown	show	VBN
cord-287670-z6ckhkgg	238	17	to	to	TO
cord-287670-z6ckhkgg	238	18	activate	activate	VB
cord-287670-z6ckhkgg	238	19	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	238	20	transcription	transcription	NN
cord-287670-z6ckhkgg	238	21	by	by	IN
cord-287670-z6ckhkgg	238	22	directly	directly	RB
cord-287670-z6ckhkgg	238	23	binding	bind	VBG
cord-287670-z6ckhkgg	238	24	to	to	IN
cord-287670-z6ckhkgg	238	25	its	-PRON-	PRP$
cord-287670-z6ckhkgg	238	26	promoter	promoter	NN
cord-287670-z6ckhkgg	238	27	region	region	NN
cord-287670-z6ckhkgg	238	28	in	in	IN
cord-287670-z6ckhkgg	238	29	response	response	NN
cord-287670-z6ckhkgg	238	30	to	to	IN
cord-287670-z6ckhkgg	238	31	cisplatin	cisplatin	NN
cord-287670-z6ckhkgg	238	32	or	or	CC
cord-287670-z6ckhkgg	238	33	5-fluorouracil	5-fluorouracil	CD
cord-287670-z6ckhkgg	238	34	treatment	treatment	NN
cord-287670-z6ckhkgg	238	35	in	in	IN
cord-287670-z6ckhkgg	238	36	human	human	JJ
cord-287670-z6ckhkgg	238	37	and	and	CC
cord-287670-z6ckhkgg	238	38	murine	murine	JJ
cord-287670-z6ckhkgg	238	39	M2	M2	NNP
cord-287670-z6ckhkgg	238	40	Figure	Figure	NNP
cord-287670-z6ckhkgg	238	41	4	4	CD
cord-287670-z6ckhkgg	238	42	.	.	.
cord-287670-z6ckhkgg	239	1	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	239	2	as	as	IN
cord-287670-z6ckhkgg	239	3	an	an	DT
cord-287670-z6ckhkgg	239	4	Extrinsic	Extrinsic	NNP
cord-287670-z6ckhkgg	239	5	Oncosuppressor	Oncosuppressor	NNP
cord-287670-z6ckhkgg	239	6	in	in	IN
cord-287670-z6ckhkgg	239	7	Cancer	Cancer	NNP
cord-287670-z6ckhkgg	239	8	.	.	.
cord-287670-z6ckhkgg	240	1	In	in	IN
cord-287670-z6ckhkgg	240	2	cancer	cancer	NN
cord-287670-z6ckhkgg	240	3	,	,	,
cord-287670-z6ckhkgg	240	4	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	240	5	gene	gene	NN
cord-287670-z6ckhkgg	240	6	and	and	CC
cord-287670-z6ckhkgg	240	7	protein	protein	NN
cord-287670-z6ckhkgg	240	8	expression	expression	NN
cord-287670-z6ckhkgg	240	9	is	be	VBZ
cord-287670-z6ckhkgg	240	10	controlled	control	VBN
cord-287670-z6ckhkgg	240	11	by	by	IN
cord-287670-z6ckhkgg	240	12	the	the	DT
cord-287670-z6ckhkgg	240	13	presence	presence	NN
cord-287670-z6ckhkgg	240	14	of	of	IN
cord-287670-z6ckhkgg	240	15	inflammatory	inflammatory	JJ
cord-287670-z6ckhkgg	240	16	mediators	mediator	NNS
cord-287670-z6ckhkgg	240	17	(	(	-LRB-
cord-287670-z6ckhkgg	240	18	e.g.	e.g.	RB
cord-287670-z6ckhkgg	240	19	,	,	,
cord-287670-z6ckhkgg	240	20	IL-1	IL-1	NNP
cord-287670-z6ckhkgg	240	21	)	)	-RRB-
cord-287670-z6ckhkgg	240	22	and/or	and/or	CC
cord-287670-z6ckhkgg	240	23	by	by	IN
cord-287670-z6ckhkgg	240	24	genetic	genetic	JJ
cord-287670-z6ckhkgg	240	25	and	and	CC
cord-287670-z6ckhkgg	240	26	epigenetic	epigenetic	JJ
cord-287670-z6ckhkgg	240	27	mechanisms	mechanism	NNS
cord-287670-z6ckhkgg	240	28	.	.	.
cord-287670-z6ckhkgg	241	1	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	241	2	regulates	regulate	VBZ
cord-287670-z6ckhkgg	241	3	complement	complement	NN
cord-287670-z6ckhkgg	241	4	-	-	HYPH
cord-287670-z6ckhkgg	241	5	dependent	dependent	JJ
cord-287670-z6ckhkgg	241	6	tumor	tumor	NN
cord-287670-z6ckhkgg	241	7	-	-	HYPH
cord-287670-z6ckhkgg	241	8	promoting	promote	VBG
cord-287670-z6ckhkgg	241	9	inflammation	inflammation	NN
cord-287670-z6ckhkgg	241	10	in	in	IN
cord-287670-z6ckhkgg	241	11	a	a	DT
cord-287670-z6ckhkgg	241	12	host	host	NN
cord-287670-z6ckhkgg	241	13	,	,	,
cord-287670-z6ckhkgg	241	14	including	include	VBG
cord-287670-z6ckhkgg	241	15	macrophage	macrophage	NN
cord-287670-z6ckhkgg	241	16	infiltration	infiltration	NN
cord-287670-z6ckhkgg	241	17	and	and	CC
cord-287670-z6ckhkgg	241	18	cytokine	cytokine	NN
cord-287670-z6ckhkgg	241	19	production	production	NN
cord-287670-z6ckhkgg	241	20	,	,	,
cord-287670-z6ckhkgg	241	21	as	as	RB
cord-287670-z6ckhkgg	241	22	well	well	RB
cord-287670-z6ckhkgg	241	23	as	as	IN
cord-287670-z6ckhkgg	241	24	fibroblast	fibroblast	NN
cord-287670-z6ckhkgg	241	25	growth	growth	NN
cord-287670-z6ckhkgg	241	26	factor	factor	NN
cord-287670-z6ckhkgg	241	27	(	(	-LRB-
cord-287670-z6ckhkgg	241	28	FGF)-dependent	fgf)-dependent	JJ
cord-287670-z6ckhkgg	241	29	angiogenesis	angiogenesis	NN
cord-287670-z6ckhkgg	241	30	,	,	,
cord-287670-z6ckhkgg	241	31	which	which	WDT
cord-287670-z6ckhkgg	241	32	can	can	MD
cord-287670-z6ckhkgg	241	33	lead	lead	VB
cord-287670-z6ckhkgg	241	34	to	to	IN
cord-287670-z6ckhkgg	241	35	genetic	genetic	JJ
cord-287670-z6ckhkgg	241	36	instability	instability	NN
cord-287670-z6ckhkgg	241	37	and	and	CC
cord-287670-z6ckhkgg	241	38	tumor	tumor	NN
cord-287670-z6ckhkgg	241	39	promotion	promotion	NN
cord-287670-z6ckhkgg	241	40	.	.	.
cord-287670-z6ckhkgg	242	1	macrophages	macrophage	NNS
cord-287670-z6ckhkgg	242	2	and	and	CC
cord-287670-z6ckhkgg	242	3	cancer	cancer	NN
cord-287670-z6ckhkgg	242	4	-	-	HYPH
cord-287670-z6ckhkgg	242	5	associated	associate	VBN
cord-287670-z6ckhkgg	242	6	fibroblasts	fibroblast	NNS
cord-287670-z6ckhkgg	242	7	.	.	.
cord-287670-z6ckhkgg	243	1	As	as	IN
cord-287670-z6ckhkgg	243	2	a	a	DT
cord-287670-z6ckhkgg	243	3	result	result	NN
cord-287670-z6ckhkgg	243	4	,	,	,
cord-287670-z6ckhkgg	243	5	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	243	6	was	be	VBD
cord-287670-z6ckhkgg	243	7	found	find	VBN
cord-287670-z6ckhkgg	243	8	to	to	TO
cord-287670-z6ckhkgg	243	9	promote	promote	VB
cord-287670-z6ckhkgg	243	10	the	the	DT
cord-287670-z6ckhkgg	243	11	growth	growth	NN
cord-287670-z6ckhkgg	243	12	,	,	,
cord-287670-z6ckhkgg	243	13	metastasis	metastasis	NN
cord-287670-z6ckhkgg	243	14	,	,	,
cord-287670-z6ckhkgg	243	15	and	and	CC
cord-287670-z6ckhkgg	243	16	invasion	invasion	NN
cord-287670-z6ckhkgg	243	17	of	of	IN
cord-287670-z6ckhkgg	243	18	drug	drug	NN
cord-287670-z6ckhkgg	243	19	-	-	HYPH
cord-287670-z6ckhkgg	243	20	resistant	resistant	JJ
cord-287670-z6ckhkgg	243	21	human	human	JJ
cord-287670-z6ckhkgg	243	22	breast	breast	NN
cord-287670-z6ckhkgg	243	23	cancer	cancer	NN
cord-287670-z6ckhkgg	243	24	cells	cell	NNS
cord-287670-z6ckhkgg	243	25	in	in	IN
cord-287670-z6ckhkgg	243	26	immunodeficient	immunodeficient	JJ
cord-287670-z6ckhkgg	243	27	mice	mouse	NNS
cord-287670-z6ckhkgg	243	28	[	[	-LRB-
cord-287670-z6ckhkgg	243	29	19	19	CD
cord-287670-z6ckhkgg	243	30	]	]	-RRB-
cord-287670-z6ckhkgg	243	31	.	.	.
cord-287670-z6ckhkgg	244	1	These	these	DT
cord-287670-z6ckhkgg	244	2	murine	murine	JJ
cord-287670-z6ckhkgg	244	3	studies	study	NNS
cord-287670-z6ckhkgg	244	4	and	and	CC
cord-287670-z6ckhkgg	244	5	the	the	DT
cord-287670-z6ckhkgg	244	6	reports	report	NNS
cord-287670-z6ckhkgg	244	7	showing	show	VBG
cord-287670-z6ckhkgg	244	8	a	a	DT
cord-287670-z6ckhkgg	244	9	positive	positive	JJ
cord-287670-z6ckhkgg	244	10	correlation	correlation	NN
cord-287670-z6ckhkgg	244	11	between	between	IN
cord-287670-z6ckhkgg	244	12	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	244	13	expression	expression	NN
cord-287670-z6ckhkgg	244	14	and	and	CC
cord-287670-z6ckhkgg	244	15	poor	poor	JJ
cord-287670-z6ckhkgg	244	16	prognosis	prognosis	NN
cord-287670-z6ckhkgg	244	17	in	in	IN
cord-287670-z6ckhkgg	244	18	specific	specific	JJ
cord-287670-z6ckhkgg	244	19	human	human	JJ
cord-287670-z6ckhkgg	244	20	cancers	cancer	NNS
cord-287670-z6ckhkgg	244	21	suggest	suggest	VBP
cord-287670-z6ckhkgg	244	22	that	that	IN
cord-287670-z6ckhkgg	244	23	the	the	DT
cord-287670-z6ckhkgg	244	24	tumor	tumor	NN
cord-287670-z6ckhkgg	244	25	-	-	HYPH
cord-287670-z6ckhkgg	244	26	promoting	promote	VBG
cord-287670-z6ckhkgg	244	27	or	or	CC
cord-287670-z6ckhkgg	244	28	tumorsuppressing	tumorsuppressing	NN
cord-287670-z6ckhkgg	244	29	role	role	NN
cord-287670-z6ckhkgg	244	30	of	of	IN
cord-287670-z6ckhkgg	244	31	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	244	32	might	may	MD
cord-287670-z6ckhkgg	244	33	very	very	RB
cord-287670-z6ckhkgg	244	34	likely	likely	RB
cord-287670-z6ckhkgg	244	35	depend	depend	VB
cord-287670-z6ckhkgg	244	36	on	on	IN
cord-287670-z6ckhkgg	244	37	tissue	tissue	NN
cord-287670-z6ckhkgg	244	38	,	,	,
cord-287670-z6ckhkgg	244	39	cancer	cancer	NN
cord-287670-z6ckhkgg	244	40	type	type	NN
cord-287670-z6ckhkgg	244	41	,	,	,
cord-287670-z6ckhkgg	244	42	and	and	CC
cord-287670-z6ckhkgg	244	43	cellular	cellular	JJ
cord-287670-z6ckhkgg	244	44	source	source	NN
cord-287670-z6ckhkgg	244	45	(	(	-LRB-
cord-287670-z6ckhkgg	244	46	e.g.	e.g.	RB
cord-287670-z6ckhkgg	244	47	,	,	,
cord-287670-z6ckhkgg	244	48	cancer	cancer	NN
cord-287670-z6ckhkgg	244	49	cells	cell	NNS
cord-287670-z6ckhkgg	244	50	versus	versus	IN
cord-287670-z6ckhkgg	244	51	tumor	tumor	NN
cord-287670-z6ckhkgg	244	52	-	-	HYPH
cord-287670-z6ckhkgg	244	53	associated	associate	VBN
cord-287670-z6ckhkgg	244	54	macrophages	macrophage	NNS
cord-287670-z6ckhkgg	244	55	or	or	CC
cord-287670-z6ckhkgg	244	56	fibroblasts	fibroblast	NNS
cord-287670-z6ckhkgg	244	57	)	)	-RRB-
cord-287670-z6ckhkgg	244	58	and	and	CC
cord-287670-z6ckhkgg	244	59	contradict	contradict	VB
cord-287670-z6ckhkgg	244	60	the	the	DT
cord-287670-z6ckhkgg	244	61	assumption	assumption	NN
cord-287670-z6ckhkgg	244	62	that	that	IN
cord-287670-z6ckhkgg	244	63	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	244	64	plays	play	VBZ
cord-287670-z6ckhkgg	244	65	a	a	DT
cord-287670-z6ckhkgg	244	66	unique	unique	JJ
cord-287670-z6ckhkgg	244	67	role	role	NN
cord-287670-z6ckhkgg	244	68	in	in	IN
cord-287670-z6ckhkgg	244	69	cancer	cancer	NN
cord-287670-z6ckhkgg	244	70	(	(	-LRB-
cord-287670-z6ckhkgg	244	71	Figures	figure	NNS
cord-287670-z6ckhkgg	244	72	3	3	CD
cord-287670-z6ckhkgg	244	73	and	and	CC
cord-287670-z6ckhkgg	244	74	4	4	CD
cord-287670-z6ckhkgg	244	75	)	)	-RRB-
cord-287670-z6ckhkgg	244	76	.	.	.
cord-287670-z6ckhkgg	245	1	However	however	RB
cord-287670-z6ckhkgg	245	2	,	,	,
cord-287670-z6ckhkgg	245	3	it	-PRON-	PRP
cord-287670-z6ckhkgg	245	4	should	should	MD
cord-287670-z6ckhkgg	245	5	be	be	VB
cord-287670-z6ckhkgg	245	6	emphasized	emphasize	VBN
cord-287670-z6ckhkgg	245	7	that	that	IN
cord-287670-z6ckhkgg	245	8	hard	hard	JJ
cord-287670-z6ckhkgg	245	9	genetic	genetic	JJ
cord-287670-z6ckhkgg	245	10	data	datum	NNS
cord-287670-z6ckhkgg	245	11	in	in	IN
cord-287670-z6ckhkgg	245	12	mice	mouse	NNS
cord-287670-z6ckhkgg	245	13	and	and	CC
cord-287670-z6ckhkgg	245	14	humans	human	NNS
cord-287670-z6ckhkgg	245	15	demonstrate	demonstrate	VBP
cord-287670-z6ckhkgg	245	16	that	that	IN
cord-287670-z6ckhkgg	245	17	this	this	DT
cord-287670-z6ckhkgg	245	18	molecule	molecule	NN
cord-287670-z6ckhkgg	245	19	is	be	VBZ
cord-287670-z6ckhkgg	245	20	a	a	DT
cord-287670-z6ckhkgg	245	21	bona	bona	JJ
cord-287670-z6ckhkgg	245	22	fide	fide	JJ
cord-287670-z6ckhkgg	245	23	cancer	cancer	NN
cord-287670-z6ckhkgg	245	24	gene	gene	NN
cord-287670-z6ckhkgg	245	25	acting	act	VBG
cord-287670-z6ckhkgg	245	26	as	as	IN
cord-287670-z6ckhkgg	245	27	an	an	DT
cord-287670-z6ckhkgg	245	28	extrinsic	extrinsic	JJ
cord-287670-z6ckhkgg	245	29	oncosuppressor	oncosuppressor	NN
cord-287670-z6ckhkgg	245	30	.	.	.
cord-287670-z6ckhkgg	246	1	Further	further	JJ
cord-287670-z6ckhkgg	246	2	research	research	NN
cord-287670-z6ckhkgg	246	3	should	should	MD
cord-287670-z6ckhkgg	246	4	help	help	VB
cord-287670-z6ckhkgg	246	5	clarify	clarify	VB
cord-287670-z6ckhkgg	246	6	these	these	DT
cord-287670-z6ckhkgg	246	7	collective	collective	JJ
cord-287670-z6ckhkgg	246	8	context	context	NN
cord-287670-z6ckhkgg	246	9	-	-	HYPH
cord-287670-z6ckhkgg	246	10	dependent	dependent	JJ
cord-287670-z6ckhkgg	246	11	findings	finding	NNS
cord-287670-z6ckhkgg	246	12	.	.	.
cord-287670-z6ckhkgg	247	1	Pentraxins	pentraxin	NNS
cord-287670-z6ckhkgg	247	2	are	be	VBP
cord-287670-z6ckhkgg	247	3	a	a	DT
cord-287670-z6ckhkgg	247	4	phylogenetically	phylogenetically	RB
cord-287670-z6ckhkgg	247	5	conserved	conserve	VBN
cord-287670-z6ckhkgg	247	6	superfamily	superfamily	NN
cord-287670-z6ckhkgg	247	7	of	of	IN
cord-287670-z6ckhkgg	247	8	humoral	humoral	JJ
cord-287670-z6ckhkgg	247	9	PRMs	prm	NNS
cord-287670-z6ckhkgg	247	10	exerting	exert	VBG
cord-287670-z6ckhkgg	247	11	common	common	JJ
cord-287670-z6ckhkgg	247	12	essential	essential	JJ
cord-287670-z6ckhkgg	247	13	functions	function	NNS
cord-287670-z6ckhkgg	247	14	in	in	IN
cord-287670-z6ckhkgg	247	15	innate	innate	JJ
cord-287670-z6ckhkgg	247	16	responses	response	NNS
cord-287670-z6ckhkgg	247	17	to	to	IN
cord-287670-z6ckhkgg	247	18	pathogens	pathogen	NNS
cord-287670-z6ckhkgg	247	19	and	and	CC
cord-287670-z6ckhkgg	247	20	in	in	IN
cord-287670-z6ckhkgg	247	21	tissue	tissue	NN
cord-287670-z6ckhkgg	247	22	repair	repair	NN
cord-287670-z6ckhkgg	247	23	.	.	.
cord-287670-z6ckhkgg	248	1	CRP	CRP	NNP
cord-287670-z6ckhkgg	248	2	is	be	VBZ
cord-287670-z6ckhkgg	248	3	a	a	DT
cord-287670-z6ckhkgg	248	4	widely	widely	RB
cord-287670-z6ckhkgg	248	5	used	use	VBN
cord-287670-z6ckhkgg	248	6	biomarker	biomarker	NN
cord-287670-z6ckhkgg	248	7	of	of	IN
cord-287670-z6ckhkgg	248	8	inflammation	inflammation	NN
cord-287670-z6ckhkgg	248	9	in	in	IN
cord-287670-z6ckhkgg	248	10	humans	human	NNS
cord-287670-z6ckhkgg	248	11	.	.	.
cord-287670-z6ckhkgg	249	1	However	however	RB
cord-287670-z6ckhkgg	249	2	,	,	,
cord-287670-z6ckhkgg	249	3	the	the	DT
cord-287670-z6ckhkgg	249	4	lack	lack	NN
cord-287670-z6ckhkgg	249	5	of	of	IN
cord-287670-z6ckhkgg	249	6	strict	strict	JJ
cord-287670-z6ckhkgg	249	7	evolutionary	evolutionary	JJ
cord-287670-z6ckhkgg	249	8	conservation	conservation	NN
cord-287670-z6ckhkgg	249	9	between	between	IN
cord-287670-z6ckhkgg	249	10	mouse	mouse	NN
cord-287670-z6ckhkgg	249	11	and	and	CC
cord-287670-z6ckhkgg	249	12	human	human	NN
cord-287670-z6ckhkgg	249	13	has	have	VBZ
cord-287670-z6ckhkgg	249	14	precluded	preclude	VBN
cord-287670-z6ckhkgg	249	15	the	the	DT
cord-287670-z6ckhkgg	249	16	use	use	NN
cord-287670-z6ckhkgg	249	17	of	of	IN
cord-287670-z6ckhkgg	249	18	straightforward	straightforward	JJ
cord-287670-z6ckhkgg	249	19	genetic	genetic	JJ
cord-287670-z6ckhkgg	249	20	approaches	approach	NNS
cord-287670-z6ckhkgg	249	21	to	to	TO
cord-287670-z6ckhkgg	249	22	explore	explore	VB
cord-287670-z6ckhkgg	249	23	its	-PRON-	PRP$
cord-287670-z6ckhkgg	249	24	functions	function	NNS
cord-287670-z6ckhkgg	249	25	in	in	IN
cord-287670-z6ckhkgg	249	26	vivo	vivo	NN
cord-287670-z6ckhkgg	249	27	.	.	.
cord-287670-z6ckhkgg	250	1	By	by	IN
cord-287670-z6ckhkgg	250	2	contrast	contrast	NN
cord-287670-z6ckhkgg	250	3	,	,	,
cord-287670-z6ckhkgg	250	4	gene	gene	NN
cord-287670-z6ckhkgg	250	5	-	-	HYPH
cord-287670-z6ckhkgg	250	6	targeting	target	VBG
cord-287670-z6ckhkgg	250	7	mouse	mouse	NN
cord-287670-z6ckhkgg	250	8	studies	study	NNS
cord-287670-z6ckhkgg	250	9	have	have	VBP
cord-287670-z6ckhkgg	250	10	allowed	allow	VBN
cord-287670-z6ckhkgg	250	11	better	well	JJR
cord-287670-z6ckhkgg	250	12	definition	definition	NN
cord-287670-z6ckhkgg	250	13	of	of	IN
cord-287670-z6ckhkgg	250	14	the	the	DT
cord-287670-z6ckhkgg	250	15	functional	functional	JJ
cord-287670-z6ckhkgg	250	16	role	role	NN
cord-287670-z6ckhkgg	250	17	of	of	IN
cord-287670-z6ckhkgg	250	18	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	250	19	in	in	IN
cord-287670-z6ckhkgg	250	20	innate	innate	JJ
cord-287670-z6ckhkgg	250	21	immunity	immunity	NN
cord-287670-z6ckhkgg	250	22	,	,	,
cord-287670-z6ckhkgg	250	23	inflammation	inflammation	NN
cord-287670-z6ckhkgg	250	24	,	,	,
cord-287670-z6ckhkgg	250	25	and	and	CC
cord-287670-z6ckhkgg	250	26	tissue	tissue	NN
cord-287670-z6ckhkgg	250	27	remodeling	remodeling	NN
cord-287670-z6ckhkgg	250	28	.	.	.
cord-287670-z6ckhkgg	251	1	In	in	IN
cord-287670-z6ckhkgg	251	2	addition	addition	NN
cord-287670-z6ckhkgg	251	3	,	,	,
cord-287670-z6ckhkgg	251	4	genetic	genetic	JJ
cord-287670-z6ckhkgg	251	5	and	and	CC
cord-287670-z6ckhkgg	251	6	epigenetic	epigenetic	JJ
cord-287670-z6ckhkgg	251	7	data	datum	NNS
cord-287670-z6ckhkgg	251	8	are	be	VBP
cord-287670-z6ckhkgg	251	9	consistent	consistent	JJ
cord-287670-z6ckhkgg	251	10	with	with	IN
cord-287670-z6ckhkgg	251	11	the	the	DT
cord-287670-z6ckhkgg	251	12	hypothesis	hypothesis	NN
cord-287670-z6ckhkgg	251	13	that	that	WDT
cord-287670-z6ckhkgg	251	14	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	251	15	exerts	exert	VBZ
cord-287670-z6ckhkgg	251	16	similar	similar	JJ
cord-287670-z6ckhkgg	251	17	functions	function	NNS
cord-287670-z6ckhkgg	251	18	in	in	IN
cord-287670-z6ckhkgg	251	19	humans	human	NNS
cord-287670-z6ckhkgg	251	20	.	.	.
cord-287670-z6ckhkgg	252	1	From	from	IN
cord-287670-z6ckhkgg	252	2	the	the	DT
cord-287670-z6ckhkgg	252	3	results	result	NNS
cord-287670-z6ckhkgg	252	4	described	describe	VBN
cord-287670-z6ckhkgg	252	5	here	here	RB
cord-287670-z6ckhkgg	252	6	it	-PRON-	PRP
cord-287670-z6ckhkgg	252	7	has	have	VBZ
cord-287670-z6ckhkgg	252	8	been	be	VBN
cord-287670-z6ckhkgg	252	9	inferred	infer	VBN
cord-287670-z6ckhkgg	252	10	that	that	IN
cord-287670-z6ckhkgg	252	11	,	,	,
cord-287670-z6ckhkgg	252	12	on	on	IN
cord-287670-z6ckhkgg	252	13	selective	selective	JJ
cord-287670-z6ckhkgg	252	14	binding	binding	NN
cord-287670-z6ckhkgg	252	15	of	of	IN
cord-287670-z6ckhkgg	252	16	conserved	conserve	VBN
cord-287670-z6ckhkgg	252	17	microbial	microbial	JJ
cord-287670-z6ckhkgg	252	18	molecules	molecule	NNS
cord-287670-z6ckhkgg	252	19	,	,	,
cord-287670-z6ckhkgg	252	20	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	252	21	generally	generally	RB
cord-287670-z6ckhkgg	252	22	exhibits	exhibit	VBZ
cord-287670-z6ckhkgg	252	23	protective	protective	JJ
cord-287670-z6ckhkgg	252	24	antibodylike	antibodylike	NN
cord-287670-z6ckhkgg	252	25	functions	function	NNS
cord-287670-z6ckhkgg	252	26	such	such	JJ
cord-287670-z6ckhkgg	252	27	as	as	IN
cord-287670-z6ckhkgg	252	28	complement	complement	NN
cord-287670-z6ckhkgg	252	29	activation	activation	NN
cord-287670-z6ckhkgg	252	30	,	,	,
cord-287670-z6ckhkgg	252	31	opsonization	opsonization	NN
cord-287670-z6ckhkgg	252	32	of	of	IN
cord-287670-z6ckhkgg	252	33	microbes	microbe	NNS
cord-287670-z6ckhkgg	252	34	,	,	,
cord-287670-z6ckhkgg	252	35	and	and	CC
cord-287670-z6ckhkgg	252	36	glycosylationdependent	glycosylationdependent	NN
cord-287670-z6ckhkgg	252	37	regulation	regulation	NN
cord-287670-z6ckhkgg	252	38	of	of	IN
cord-287670-z6ckhkgg	252	39	inflammation	inflammation	NN
cord-287670-z6ckhkgg	252	40	.	.	.
cord-287670-z6ckhkgg	253	1	Furthermore	furthermore	RB
cord-287670-z6ckhkgg	253	2	,	,	,
cord-287670-z6ckhkgg	253	3	studies	study	NNS
cord-287670-z6ckhkgg	253	4	in	in	IN
cord-287670-z6ckhkgg	253	5	tissue	tissue	NN
cord-287670-z6ckhkgg	253	6	repair	repair	NN
cord-287670-z6ckhkgg	253	7	models	model	NNS
cord-287670-z6ckhkgg	253	8	have	have	VBP
cord-287670-z6ckhkgg	253	9	shown	show	VBN
cord-287670-z6ckhkgg	253	10	that	that	IN
cord-287670-z6ckhkgg	253	11	PTX3-dependent	ptx3-dependent	NN
cord-287670-z6ckhkgg	253	12	promotion	promotion	NN
cord-287670-z6ckhkgg	253	13	of	of	IN
cord-287670-z6ckhkgg	253	14	fibrin	fibrin	NN
cord-287670-z6ckhkgg	253	15	-	-	HYPH
cord-287670-z6ckhkgg	253	16	rich	rich	JJ
cord-287670-z6ckhkgg	253	17	inflammatory	inflammatory	JJ
cord-287670-z6ckhkgg	253	18	matrix	matrix	NN
cord-287670-z6ckhkgg	253	19	remodeling	remodeling	NN
cord-287670-z6ckhkgg	253	20	contributes	contribute	VBZ
cord-287670-z6ckhkgg	253	21	to	to	IN
cord-287670-z6ckhkgg	253	22	tissue	tissue	NN
cord-287670-z6ckhkgg	253	23	repair	repair	NN
cord-287670-z6ckhkgg	253	24	and	and	CC
cord-287670-z6ckhkgg	253	25	underline	underline	VB
cord-287670-z6ckhkgg	253	26	the	the	DT
cord-287670-z6ckhkgg	253	27	evolutionary	evolutionary	JJ
cord-287670-z6ckhkgg	253	28	link	link	NN
cord-287670-z6ckhkgg	253	29	that	that	WDT
cord-287670-z6ckhkgg	253	30	exists	exist	VBZ
cord-287670-z6ckhkgg	253	31	between	between	IN
cord-287670-z6ckhkgg	253	32	microbial	microbial	NN
cord-287670-z6ckhkgg	253	33	and	and	CC
cord-287670-z6ckhkgg	253	34	ECM	ECM	NNP
cord-287670-z6ckhkgg	253	35	recognition	recognition	NN
cord-287670-z6ckhkgg	253	36	in	in	IN
cord-287670-z6ckhkgg	253	37	the	the	DT
cord-287670-z6ckhkgg	253	38	humoral	humoral	JJ
cord-287670-z6ckhkgg	253	39	arm	arm	NN
cord-287670-z6ckhkgg	253	40	of	of	IN
cord-287670-z6ckhkgg	253	41	innate	innate	JJ
cord-287670-z6ckhkgg	253	42	immunity	immunity	NN
cord-287670-z6ckhkgg	253	43	.	.	.
cord-287670-z6ckhkgg	254	1	Thus	thus	RB
cord-287670-z6ckhkgg	254	2	,	,	,
cord-287670-z6ckhkgg	254	3	genetic	genetic	JJ
cord-287670-z6ckhkgg	254	4	evidence	evidence	NN
cord-287670-z6ckhkgg	254	5	in	in	IN
cord-287670-z6ckhkgg	254	6	mouse	mouse	NN
cord-287670-z6ckhkgg	254	7	and	and	CC
cord-287670-z6ckhkgg	254	8	human	human	NN
cord-287670-z6ckhkgg	254	9	indicates	indicate	VBZ
cord-287670-z6ckhkgg	254	10	that	that	IN
cord-287670-z6ckhkgg	254	11	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	254	12	is	be	VBZ
cord-287670-z6ckhkgg	254	13	essential	essential	JJ
cord-287670-z6ckhkgg	254	14	for	for	IN
cord-287670-z6ckhkgg	254	15	resistance	resistance	NN
cord-287670-z6ckhkgg	254	16	against	against	IN
cord-287670-z6ckhkgg	254	17	selected	select	VBN
cord-287670-z6ckhkgg	254	18	pathogens	pathogen	NNS
cord-287670-z6ckhkgg	254	19	and	and	CC
cord-287670-z6ckhkgg	254	20	that	that	IN
cord-287670-z6ckhkgg	254	21	it	-PRON-	PRP
cord-287670-z6ckhkgg	254	22	also	also	RB
cord-287670-z6ckhkgg	254	23	promotes	promote	VBZ
cord-287670-z6ckhkgg	254	24	tissue	tissue	NN
cord-287670-z6ckhkgg	254	25	repair	repair	NN
cord-287670-z6ckhkgg	254	26	.	.	.
cord-287670-z6ckhkgg	255	1	The	the	DT
cord-287670-z6ckhkgg	255	2	described	describe	VBN
cord-287670-z6ckhkgg	255	3	findings	finding	NNS
cord-287670-z6ckhkgg	255	4	strongly	strongly	RB
cord-287670-z6ckhkgg	255	5	support	support	VBP
cord-287670-z6ckhkgg	255	6	the	the	DT
cord-287670-z6ckhkgg	255	7	promising	promising	JJ
cord-287670-z6ckhkgg	255	8	potential	potential	NN
cord-287670-z6ckhkgg	255	9	of	of	IN
cord-287670-z6ckhkgg	255	10	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	255	11	in	in	IN
cord-287670-z6ckhkgg	255	12	prophylaxis	prophylaxis	NN
cord-287670-z6ckhkgg	255	13	and	and	CC
cord-287670-z6ckhkgg	255	14	therapy	therapy	NN
cord-287670-z6ckhkgg	255	15	against	against	IN
cord-287670-z6ckhkgg	255	16	infectious	infectious	JJ
cord-287670-z6ckhkgg	255	17	diseases	disease	NNS
cord-287670-z6ckhkgg	255	18	in	in	IN
cord-287670-z6ckhkgg	255	19	specific	specific	JJ
cord-287670-z6ckhkgg	255	20	clinical	clinical	JJ
cord-287670-z6ckhkgg	255	21	settings	setting	NNS
cord-287670-z6ckhkgg	255	22	.	.	.
cord-287670-z6ckhkgg	256	1	Of	of	IN
cord-287670-z6ckhkgg	256	2	note	note	NN
cord-287670-z6ckhkgg	256	3	,	,	,
cord-287670-z6ckhkgg	256	4	the	the	DT
cord-287670-z6ckhkgg	256	5	regulation	regulation	NN
cord-287670-z6ckhkgg	256	6	of	of	IN
cord-287670-z6ckhkgg	256	7	complement	complement	JJ
cord-287670-z6ckhkgg	256	8	activation	activation	NN
cord-287670-z6ckhkgg	256	9	also	also	RB
cord-287670-z6ckhkgg	256	10	appears	appear	VBZ
cord-287670-z6ckhkgg	256	11	to	to	TO
cord-287670-z6ckhkgg	256	12	be	be	VB
cord-287670-z6ckhkgg	256	13	an	an	DT
cord-287670-z6ckhkgg	256	14	essential	essential	JJ
cord-287670-z6ckhkgg	256	15	mechanism	mechanism	NN
cord-287670-z6ckhkgg	256	16	of	of	IN
cord-287670-z6ckhkgg	256	17	action	action	NN
cord-287670-z6ckhkgg	256	18	for	for	IN
cord-287670-z6ckhkgg	256	19	the	the	DT
cord-287670-z6ckhkgg	256	20	oncosuppressive	oncosuppressive	JJ
cord-287670-z6ckhkgg	256	21	role	role	NN
cord-287670-z6ckhkgg	256	22	of	of	IN
cord-287670-z6ckhkgg	256	23	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	256	24	that	that	WDT
cord-287670-z6ckhkgg	256	25	has	have	VBZ
cord-287670-z6ckhkgg	256	26	been	be	VBN
cord-287670-z6ckhkgg	256	27	recently	recently	RB
cord-287670-z6ckhkgg	256	28	described	describe	VBN
cord-287670-z6ckhkgg	256	29	,	,	,
cord-287670-z6ckhkgg	256	30	suggesting	suggest	VBG
cord-287670-z6ckhkgg	256	31	that	that	IN
cord-287670-z6ckhkgg	256	32	novel	novel	JJ
cord-287670-z6ckhkgg	256	33	therapeutic	therapeutic	JJ
cord-287670-z6ckhkgg	256	34	approaches	approach	NNS
cord-287670-z6ckhkgg	256	35	could	could	MD
cord-287670-z6ckhkgg	256	36	be	be	VB
cord-287670-z6ckhkgg	256	37	envisioned	envision	VBN
cord-287670-z6ckhkgg	256	38	.	.	.
cord-287670-z6ckhkgg	257	1	However	however	RB
cord-287670-z6ckhkgg	257	2	,	,	,
cord-287670-z6ckhkgg	257	3	several	several	JJ
cord-287670-z6ckhkgg	257	4	issues	issue	NNS
cord-287670-z6ckhkgg	257	5	remain	remain	VBP
cord-287670-z6ckhkgg	257	6	(	(	-LRB-
cord-287670-z6ckhkgg	257	7	see	see	VB
cord-287670-z6ckhkgg	257	8	Outstanding	Outstanding	NNP
cord-287670-z6ckhkgg	257	9	Questions	Questions	NNPS
cord-287670-z6ckhkgg	257	10	)	)	-RRB-
cord-287670-z6ckhkgg	257	11	.	.	.
cord-287670-z6ckhkgg	258	1	For	for	IN
cord-287670-z6ckhkgg	258	2	example	example	NN
cord-287670-z6ckhkgg	258	3	,	,	,
cord-287670-z6ckhkgg	258	4	it	-PRON-	PRP
cord-287670-z6ckhkgg	258	5	is	be	VBZ
cord-287670-z6ckhkgg	258	6	important	important	JJ
cord-287670-z6ckhkgg	258	7	to	to	TO
cord-287670-z6ckhkgg	258	8	take	take	VB
cord-287670-z6ckhkgg	258	9	into	into	IN
cord-287670-z6ckhkgg	258	10	account	account	NN
cord-287670-z6ckhkgg	258	11	that	that	WDT
cord-287670-z6ckhkgg	258	12	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	258	13	could	could	MD
cord-287670-z6ckhkgg	258	14	potentially	potentially	RB
cord-287670-z6ckhkgg	258	15	lead	lead	VB
cord-287670-z6ckhkgg	258	16	to	to	IN
cord-287670-z6ckhkgg	258	17	harmful	harmful	JJ
cord-287670-z6ckhkgg	258	18	consequences	consequence	NNS
cord-287670-z6ckhkgg	258	19	in	in	IN
cord-287670-z6ckhkgg	258	20	an	an	DT
cord-287670-z6ckhkgg	258	21	organism	organism	NN
cord-287670-z6ckhkgg	258	22	under	under	IN
cord-287670-z6ckhkgg	258	23	certain	certain	JJ
cord-287670-z6ckhkgg	258	24	circumstances	circumstance	NNS
cord-287670-z6ckhkgg	258	25	.	.	.
cord-287670-z6ckhkgg	259	1	Consequently	consequently	RB
cord-287670-z6ckhkgg	259	2	,	,	,
cord-287670-z6ckhkgg	259	3	when	when	WRB
cord-287670-z6ckhkgg	259	4	considering	consider	VBG
cord-287670-z6ckhkgg	259	5	the	the	DT
cord-287670-z6ckhkgg	259	6	exploitation	exploitation	NN
cord-287670-z6ckhkgg	259	7	of	of	IN
cord-287670-z6ckhkgg	259	8	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	259	9	by	by	IN
cord-287670-z6ckhkgg	259	10	viruses	virus	NNS
cord-287670-z6ckhkgg	259	11	(	(	-LRB-
cord-287670-z6ckhkgg	259	12	such	such	JJ
cord-287670-z6ckhkgg	259	13	as	as	IN
cord-287670-z6ckhkgg	259	14	alphaviruses	alphaviruses	NNP
cord-287670-z6ckhkgg	259	15	)	)	-RRB-
cord-287670-z6ckhkgg	259	16	to	to	TO
cord-287670-z6ckhkgg	259	17	facilitate	facilitate	VB
cord-287670-z6ckhkgg	259	18	viral	viral	JJ
cord-287670-z6ckhkgg	259	19	entry	entry	NN
cord-287670-z6ckhkgg	259	20	into	into	IN
cord-287670-z6ckhkgg	259	21	host	host	NN
cord-287670-z6ckhkgg	259	22	cells	cell	NNS
cord-287670-z6ckhkgg	259	23	[	[	-LRB-
cord-287670-z6ckhkgg	259	24	55	55	CD
cord-287670-z6ckhkgg	259	25	]	]	-RRB-
cord-287670-z6ckhkgg	259	26	(	(	-LRB-
cord-287670-z6ckhkgg	259	27	Figures	figure	NNS
cord-287670-z6ckhkgg	259	28	2	2	CD
cord-287670-z6ckhkgg	259	29	and	and	CC
cord-287670-z6ckhkgg	259	30	3	3	CD
cord-287670-z6ckhkgg	259	31	)	)	-RRB-
cord-287670-z6ckhkgg	259	32	,	,	,
cord-287670-z6ckhkgg	259	33	the	the	DT
cord-287670-z6ckhkgg	259	34	interaction	interaction	NN
cord-287670-z6ckhkgg	259	35	of	of	IN
cord-287670-z6ckhkgg	259	36	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	259	37	with	with	IN
cord-287670-z6ckhkgg	259	38	collectins	collectin	NNS
cord-287670-z6ckhkgg	259	39	and	and	CC
cord-287670-z6ckhkgg	259	40	ficolins	ficolins	NNPS
cord-287670-z6ckhkgg	259	41	,	,	,
cord-287670-z6ckhkgg	259	42	which	which	WDT
cord-287670-z6ckhkgg	259	43	can	can	MD
cord-287670-z6ckhkgg	259	44	lead	lead	VB
cord-287670-z6ckhkgg	259	45	to	to	IN
cord-287670-z6ckhkgg	259	46	potent	potent	JJ
cord-287670-z6ckhkgg	259	47	synergic	synergic	JJ
cord-287670-z6ckhkgg	259	48	complement	complement	NN
cord-287670-z6ckhkgg	259	49	activation	activation	NN
cord-287670-z6ckhkgg	259	50	[	[	-LRB-
cord-287670-z6ckhkgg	259	51	32	32	CD
cord-287670-z6ckhkgg	259	52	]	]	-RRB-
cord-287670-z6ckhkgg	259	53	,	,	,
cord-287670-z6ckhkgg	259	54	as	as	RB
cord-287670-z6ckhkgg	259	55	well	well	RB
cord-287670-z6ckhkgg	259	56	as	as	IN
cord-287670-z6ckhkgg	259	57	its	-PRON-	PRP$
cord-287670-z6ckhkgg	259	58	potential	potential	NN
cord-287670-z6ckhkgg	259	59	to	to	TO
cord-287670-z6ckhkgg	259	60	induce	induce	VB
cord-287670-z6ckhkgg	259	61	endothelial	endothelial	JJ
cord-287670-z6ckhkgg	259	62	dysfunction	dysfunction	NN
cord-287670-z6ckhkgg	259	63	[	[	-LRB-
cord-287670-z6ckhkgg	259	64	79	79	CD
cord-287670-z6ckhkgg	259	65	]	]	-RRB-
cord-287670-z6ckhkgg	259	66	and	and	CC
cord-287670-z6ckhkgg	259	67	inflammation	inflammation	NN
cord-287670-z6ckhkgg	259	68	[	[	-LRB-
cord-287670-z6ckhkgg	259	69	19	19	CD
cord-287670-z6ckhkgg	259	70	,	,	,
cord-287670-z6ckhkgg	259	71	76	76	CD
cord-287670-z6ckhkgg	259	72	]	]	-RRB-
cord-287670-z6ckhkgg	260	1	(	(	-LRB-
cord-287670-z6ckhkgg	260	2	Figure	figure	NN
cord-287670-z6ckhkgg	260	3	3	3	CD
cord-287670-z6ckhkgg	260	4	)	)	-RRB-
cord-287670-z6ckhkgg	260	5	,	,	,
cord-287670-z6ckhkgg	260	6	future	future	JJ
cord-287670-z6ckhkgg	260	7	clinical	clinical	JJ
cord-287670-z6ckhkgg	260	8	trials	trial	NNS
cord-287670-z6ckhkgg	260	9	involving	involve	VBG
cord-287670-z6ckhkgg	260	10	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	260	11	administration	administration	NN
cord-287670-z6ckhkgg	260	12	(	(	-LRB-
cord-287670-z6ckhkgg	260	13	or	or	CC
cord-287670-z6ckhkgg	260	14	blockade	blockade	NN
cord-287670-z6ckhkgg	260	15	)	)	-RRB-
cord-287670-z6ckhkgg	260	16	should	should	MD
cord-287670-z6ckhkgg	260	17	carefully	carefully	RB
cord-287670-z6ckhkgg	260	18	assess	assess	VB
cord-287670-z6ckhkgg	260	19	the	the	DT
cord-287670-z6ckhkgg	260	20	possibility	possibility	NN
cord-287670-z6ckhkgg	260	21	of	of	IN
cord-287670-z6ckhkgg	260	22	generating	generate	VBG
cord-287670-z6ckhkgg	260	23	unbalanced	unbalanced	JJ
cord-287670-z6ckhkgg	260	24	inflammatory	inflammatory	JJ
cord-287670-z6ckhkgg	260	25	responses	response	NNS
cord-287670-z6ckhkgg	260	26	and	and	CC
cord-287670-z6ckhkgg	260	27	other	other	JJ
cord-287670-z6ckhkgg	260	28	adverse	adverse	JJ
cord-287670-z6ckhkgg	260	29	clinical	clinical	JJ
cord-287670-z6ckhkgg	260	30	outcomes	outcome	NNS
cord-287670-z6ckhkgg	260	31	.	.	.
cord-287670-z6ckhkgg	261	1	Finally	finally	RB
cord-287670-z6ckhkgg	261	2	,	,	,
cord-287670-z6ckhkgg	261	3	a	a	DT
cord-287670-z6ckhkgg	261	4	call	call	NN
cord-287670-z6ckhkgg	261	5	is	be	VBZ
cord-287670-z6ckhkgg	261	6	made	make	VBN
cord-287670-z6ckhkgg	261	7	to	to	TO
cord-287670-z6ckhkgg	261	8	strive	strive	VB
cord-287670-z6ckhkgg	261	9	to	to	TO
cord-287670-z6ckhkgg	261	10	achieve	achieve	VB
cord-287670-z6ckhkgg	261	11	a	a	DT
cord-287670-z6ckhkgg	261	12	better	well	JJR
cord-287670-z6ckhkgg	261	13	understanding	understanding	NN
cord-287670-z6ckhkgg	261	14	of	of	IN
cord-287670-z6ckhkgg	261	15	the	the	DT
cord-287670-z6ckhkgg	261	16	multiple	multiple	JJ
cord-287670-z6ckhkgg	261	17	mechanistic	mechanistic	JJ
cord-287670-z6ckhkgg	261	18	pathways	pathway	NNS
cord-287670-z6ckhkgg	261	19	in	in	IN
cord-287670-z6ckhkgg	261	20	which	which	WDT
cord-287670-z6ckhkgg	261	21	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	261	22	is	be	VBZ
cord-287670-z6ckhkgg	261	23	involved	involve	VBN
cord-287670-z6ckhkgg	261	24	.	.	.
cord-287670-z6ckhkgg	262	1	Deciphering	decipher	VBG
cord-287670-z6ckhkgg	262	2	more	more	RBR
cord-287670-z6ckhkgg	262	3	clearly	clearly	RB
cord-287670-z6ckhkgg	262	4	the	the	DT
cord-287670-z6ckhkgg	262	5	multifaceted	multifaceted	JJ
cord-287670-z6ckhkgg	262	6	functional	functional	JJ
cord-287670-z6ckhkgg	262	7	roles	role	NNS
cord-287670-z6ckhkgg	262	8	of	of	IN
cord-287670-z6ckhkgg	262	9	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	262	10	in	in	IN
cord-287670-z6ckhkgg	262	11	physiology	physiology	NN
cord-287670-z6ckhkgg	262	12	may	may	MD
cord-287670-z6ckhkgg	262	13	facilitate	facilitate	VB
cord-287670-z6ckhkgg	262	14	the	the	DT
cord-287670-z6ckhkgg	262	15	development	development	NN
cord-287670-z6ckhkgg	262	16	of	of	IN
cord-287670-z6ckhkgg	262	17	targeted	target	VBN
cord-287670-z6ckhkgg	262	18	therapeutic	therapeutic	JJ
cord-287670-z6ckhkgg	262	19	approaches	approach	NNS
cord-287670-z6ckhkgg	262	20	in	in	IN
cord-287670-z6ckhkgg	262	21	various	various	JJ
cord-287670-z6ckhkgg	262	22	clinical	clinical	JJ
cord-287670-z6ckhkgg	262	23	conditions	condition	NNS
cord-287670-z6ckhkgg	262	24	.	.	.
cord-287670-z6ckhkgg	263	1	The	the	DT
cord-287670-z6ckhkgg	263	2	.	.	.
cord-287670-z6ckhkgg	264	1	What	what	WP
cord-287670-z6ckhkgg	264	2	is	be	VBZ
cord-287670-z6ckhkgg	264	3	the	the	DT
cord-287670-z6ckhkgg	264	4	impact	impact	NN
cord-287670-z6ckhkgg	264	5	of	of	IN
cord-287670-z6ckhkgg	264	6	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	264	7	as	as	IN
cord-287670-z6ckhkgg	264	8	a	a	DT
cord-287670-z6ckhkgg	264	9	genetic	genetic	JJ
cord-287670-z6ckhkgg	264	10	or	or	CC
cord-287670-z6ckhkgg	264	11	circulating	circulate	VBG
cord-287670-z6ckhkgg	264	12	protein	protein	NN
cord-287670-z6ckhkgg	264	13	marker	marker	NN
cord-287670-z6ckhkgg	264	14	on	on	IN
cord-287670-z6ckhkgg	264	15	disease	disease	NN
cord-287670-z6ckhkgg	264	16	management	management	NN
cord-287670-z6ckhkgg	264	17	for	for	IN
cord-287670-z6ckhkgg	264	18	specific	specific	JJ
cord-287670-z6ckhkgg	264	19	clinical	clinical	JJ
cord-287670-z6ckhkgg	264	20	conditions	condition	NNS
cord-287670-z6ckhkgg	264	21	?	?	.
cord-287670-z6ckhkgg	265	1	In	in	IN
cord-287670-z6ckhkgg	265	2	what	what	WP
cord-287670-z6ckhkgg	265	3	immediate	immediate	JJ
cord-287670-z6ckhkgg	265	4	conditions	condition	NNS
cord-287670-z6ckhkgg	265	5	can	can	MD
cord-287670-z6ckhkgg	265	6	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	265	7	be	be	VB
cord-287670-z6ckhkgg	265	8	assessed	assess	VBN
cord-287670-z6ckhkgg	265	9	?	?	.
cord-287670-z6ckhkgg	266	1	What	what	WP
cord-287670-z6ckhkgg	266	2	is	be	VBZ
cord-287670-z6ckhkgg	266	3	the	the	DT
cord-287670-z6ckhkgg	266	4	mechanistic	mechanistic	JJ
cord-287670-z6ckhkgg	266	5	basis	basis	NN
cord-287670-z6ckhkgg	266	6	of	of	IN
cord-287670-z6ckhkgg	266	7	the	the	DT
cord-287670-z6ckhkgg	266	8	oncosuppressive	oncosuppressive	JJ
cord-287670-z6ckhkgg	266	9	role	role	NN
cord-287670-z6ckhkgg	266	10	of	of	IN
cord-287670-z6ckhkgg	266	11	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	266	12	in	in	IN
cord-287670-z6ckhkgg	266	13	various	various	JJ
cord-287670-z6ckhkgg	266	14	forms	form	NNS
cord-287670-z6ckhkgg	266	15	of	of	IN
cord-287670-z6ckhkgg	266	16	cancer	cancer	NN
cord-287670-z6ckhkgg	266	17	?	?	.
cord-287670-z6ckhkgg	267	1	Does	do	VBZ
cord-287670-z6ckhkgg	267	2	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	267	3	play	play	VB
cord-287670-z6ckhkgg	267	4	differential	differential	NN
cord-287670-z6ckhkgg	267	5	or	or	CC
cord-287670-z6ckhkgg	267	6	redundant	redundant	JJ
cord-287670-z6ckhkgg	267	7	roles	role	NNS
cord-287670-z6ckhkgg	267	8	in	in	IN
cord-287670-z6ckhkgg	267	9	diverse	diverse	JJ
cord-287670-z6ckhkgg	267	10	forms	form	NNS
cord-287670-z6ckhkgg	267	11	of	of	IN
cord-287670-z6ckhkgg	267	12	cancer	cancer	NN
cord-287670-z6ckhkgg	267	13	?	?	.
cord-287670-z6ckhkgg	268	1	What	what	WP
cord-287670-z6ckhkgg	268	2	is	be	VBZ
cord-287670-z6ckhkgg	268	3	the	the	DT
cord-287670-z6ckhkgg	268	4	role	role	NN
cord-287670-z6ckhkgg	268	5	of	of	IN
cord-287670-z6ckhkgg	268	6	complement	complement	NN
cord-287670-z6ckhkgg	268	7	in	in	IN
cord-287670-z6ckhkgg	268	8	carcinogenesis	carcinogenesis	NN
cord-287670-z6ckhkgg	268	9	and	and	CC
cord-287670-z6ckhkgg	268	10	human	human	JJ
cord-287670-z6ckhkgg	268	11	cancer	cancer	NN
cord-287670-z6ckhkgg	268	12	?	?	.
cord-287670-z6ckhkgg	269	1	What	what	WP
cord-287670-z6ckhkgg	269	2	is	be	VBZ
cord-287670-z6ckhkgg	269	3	the	the	DT
cord-287670-z6ckhkgg	269	4	role	role	NN
cord-287670-z6ckhkgg	269	5	of	of	IN
cord-287670-z6ckhkgg	269	6	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	269	7	in	in	IN
cord-287670-z6ckhkgg	269	8	antiviral	antiviral	JJ
cord-287670-z6ckhkgg	269	9	resistance	resistance	NN
cord-287670-z6ckhkgg	269	10	?	?	.
cord-287670-z6ckhkgg	270	1	What	what	WDT
cord-287670-z6ckhkgg	270	2	impact	impact	NN
cord-287670-z6ckhkgg	270	3	does	do	VBZ
cord-287670-z6ckhkgg	270	4	it	-PRON-	PRP
cord-287670-z6ckhkgg	270	5	have	have	VB
cord-287670-z6ckhkgg	270	6	in	in	IN
cord-287670-z6ckhkgg	270	7	mediating	mediate	VBG
cord-287670-z6ckhkgg	270	8	antiviral	antiviral	JJ
cord-287670-z6ckhkgg	270	9	defense	defense	NN
cord-287670-z6ckhkgg	270	10	versus	versus	IN
cord-287670-z6ckhkgg	270	11	facilitating	facilitate	VBG
cord-287670-z6ckhkgg	270	12	viral	viral	JJ
cord-287670-z6ckhkgg	270	13	entry	entry	NN
cord-287670-z6ckhkgg	270	14	?	?	.
cord-287670-z6ckhkgg	271	1	For	for	IN
cord-287670-z6ckhkgg	271	2	which	which	WDT
cord-287670-z6ckhkgg	271	3	different	different	JJ
cord-287670-z6ckhkgg	271	4	types	type	NNS
cord-287670-z6ckhkgg	271	5	of	of	IN
cord-287670-z6ckhkgg	271	6	virus	virus	NN
cord-287670-z6ckhkgg	271	7	does	do	VBZ
cord-287670-z6ckhkgg	271	8	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	271	9	facilitate	facilitate	VB
cord-287670-z6ckhkgg	271	10	viral	viral	JJ
cord-287670-z6ckhkgg	271	11	entry	entry	NN
cord-287670-z6ckhkgg	271	12	?	?	.
cord-287670-z6ckhkgg	272	1	What	what	WP
cord-287670-z6ckhkgg	272	2	is	be	VBZ
cord-287670-z6ckhkgg	272	3	the	the	DT
cord-287670-z6ckhkgg	272	4	therapeutic	therapeutic	JJ
cord-287670-z6ckhkgg	272	5	potential	potential	NN
cord-287670-z6ckhkgg	272	6	of	of	IN
cord-287670-z6ckhkgg	272	7	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	272	8	in	in	IN
cord-287670-z6ckhkgg	272	9	specific	specific	JJ
cord-287670-z6ckhkgg	272	10	microbial	microbial	JJ
cord-287670-z6ckhkgg	272	11	infections	infection	NNS
cord-287670-z6ckhkgg	272	12	(	(	-LRB-
cord-287670-z6ckhkgg	272	13	e.g.	e.g.	RB
cord-287670-z6ckhkgg	272	14	,	,	,
cord-287670-z6ckhkgg	272	15	Aspergillus	aspergillus	NN
cord-287670-z6ckhkgg	272	16	fumigatus	fumigatus	NN
cord-287670-z6ckhkgg	272	17	,	,	,
cord-287670-z6ckhkgg	272	18	Pseudomonas	Pseudomonas	NNP
cord-287670-z6ckhkgg	272	19	aeruginosa	aeruginosa	NN
cord-287670-z6ckhkgg	272	20	)	)	-RRB-
cord-287670-z6ckhkgg	272	21	?	?	.
cord-287670-z6ckhkgg	273	1	What	what	WP
cord-287670-z6ckhkgg	273	2	is	be	VBZ
cord-287670-z6ckhkgg	273	3	the	the	DT
cord-287670-z6ckhkgg	273	4	mechanistic	mechanistic	JJ
cord-287670-z6ckhkgg	273	5	basis	basis	NN
cord-287670-z6ckhkgg	273	6	for	for	IN
cord-287670-z6ckhkgg	273	7	the	the	DT
cord-287670-z6ckhkgg	273	8	observed	observed	JJ
cord-287670-z6ckhkgg	273	9	antagonistic	antagonistic	JJ
cord-287670-z6ckhkgg	273	10	effects	effect	NNS
cord-287670-z6ckhkgg	273	11	of	of	IN
cord-287670-z6ckhkgg	273	12	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	273	13	in	in	IN
cord-287670-z6ckhkgg	273	14	response	response	NN
cord-287670-z6ckhkgg	273	15	to	to	IN
cord-287670-z6ckhkgg	273	16	varying	vary	VBG
cord-287670-z6ckhkgg	273	17	bacterial	bacterial	JJ
cord-287670-z6ckhkgg	273	18	burdens	burden	NNS
cord-287670-z6ckhkgg	273	19	during	during	IN
cord-287670-z6ckhkgg	273	20	an	an	DT
cord-287670-z6ckhkgg	273	21	infection	infection	NN
cord-287670-z6ckhkgg	273	22	and	and	CC
cord-287670-z6ckhkgg	273	23	is	be	VBZ
cord-287670-z6ckhkgg	273	24	there	there	EX
cord-287670-z6ckhkgg	273	25	a	a	DT
cord-287670-z6ckhkgg	273	26	threshold	threshold	NN
cord-287670-z6ckhkgg	273	27	?	?	.
cord-287670-z6ckhkgg	274	1	Would	Would	MD
cord-287670-z6ckhkgg	274	2	this	this	DT
cord-287670-z6ckhkgg	274	3	phenomenon	phenomenon	NN
cord-287670-z6ckhkgg	274	4	apply	apply	VB
cord-287670-z6ckhkgg	274	5	to	to	IN
cord-287670-z6ckhkgg	274	6	different	different	JJ
cord-287670-z6ckhkgg	274	7	pathogens	pathogen	NNS
cord-287670-z6ckhkgg	274	8	?	?	.
cord-287670-z6ckhkgg	275	1	Is	be	VBZ
cord-287670-z6ckhkgg	275	2	there	there	EX
cord-287670-z6ckhkgg	275	3	an	an	DT
cord-287670-z6ckhkgg	275	4	underlying	underlie	VBG
cord-287670-z6ckhkgg	275	5	functional	functional	JJ
cord-287670-z6ckhkgg	275	6	advantage	advantage	NN
cord-287670-z6ckhkgg	275	7	in	in	IN
cord-287670-z6ckhkgg	275	8	response	response	NN
cord-287670-z6ckhkgg	275	9	to	to	IN
cord-287670-z6ckhkgg	275	10	these	these	DT
cord-287670-z6ckhkgg	275	11	different	different	JJ
cord-287670-z6ckhkgg	275	12	scenarios	scenario	NNS
cord-287670-z6ckhkgg	275	13	for	for	IN
cord-287670-z6ckhkgg	275	14	the	the	DT
cord-287670-z6ckhkgg	275	15	host	host	NN
cord-287670-z6ckhkgg	275	16	?	?	.
cord-287670-z6ckhkgg	275	17	 	 	_SP
cord-287670-z6ckhkgg	276	1	Acute	acute	JJ
cord-287670-z6ckhkgg	276	2	-	-	HYPH
cord-287670-z6ckhkgg	276	3	phase	phase	NN
cord-287670-z6ckhkgg	276	4	proteins	protein	NNS
cord-287670-z6ckhkgg	276	5	and	and	CC
cord-287670-z6ckhkgg	276	6	other	other	JJ
cord-287670-z6ckhkgg	276	7	systemic	systemic	JJ
cord-287670-z6ckhkgg	276	8	responses	response	NNS
cord-287670-z6ckhkgg	276	9	to	to	IN
cord-287670-z6ckhkgg	276	10	inflammation	inflammation	NN
cord-287670-z6ckhkgg	276	11	Negative	negative	JJ
cord-287670-z6ckhkgg	276	12	regulatory	regulatory	JJ
cord-287670-z6ckhkgg	276	13	receptors	receptor	NNS
cord-287670-z6ckhkgg	276	14	of	of	IN
cord-287670-z6ckhkgg	277	1	the	the	DT
cord-287670-z6ckhkgg	277	2	IL-1	IL-1	NNP
cord-287670-z6ckhkgg	277	3	family	family	NN
cord-287670-z6ckhkgg	277	4	An	an	DT
cord-287670-z6ckhkgg	277	5	integrated	integrated	JJ
cord-287670-z6ckhkgg	277	6	view	view	NN
cord-287670-z6ckhkgg	277	7	of	of	IN
cord-287670-z6ckhkgg	277	8	humoral	humoral	JJ
cord-287670-z6ckhkgg	277	9	innate	innate	JJ
cord-287670-z6ckhkgg	277	10	immunity	immunity	NN
cord-287670-z6ckhkgg	277	11	:	:	:
cord-287670-z6ckhkgg	277	12	pentraxins	pentraxin	NNS
cord-287670-z6ckhkgg	277	13	as	as	IN
cord-287670-z6ckhkgg	277	14	a	a	DT
cord-287670-z6ckhkgg	277	15	paradigm	paradigm	NN
cord-287670-z6ckhkgg	277	16	Pentraxins	Pentraxins	NNP
cord-287670-z6ckhkgg	277	17	at	at	IN
cord-287670-z6ckhkgg	277	18	the	the	DT
cord-287670-z6ckhkgg	277	19	crossroads	crossroad	NNS
cord-287670-z6ckhkgg	277	20	between	between	IN
cord-287670-z6ckhkgg	277	21	innate	innate	JJ
cord-287670-z6ckhkgg	277	22	immunity	immunity	NN
cord-287670-z6ckhkgg	277	23	,	,	,
cord-287670-z6ckhkgg	277	24	inflammation	inflammation	NN
cord-287670-z6ckhkgg	277	25	,	,	,
cord-287670-z6ckhkgg	277	26	matrix	matrix	NN
cord-287670-z6ckhkgg	277	27	deposition	deposition	NN
cord-287670-z6ckhkgg	277	28	,	,	,
cord-287670-z6ckhkgg	277	29	and	and	CC
cord-287670-z6ckhkgg	277	30	female	female	JJ
cord-287670-z6ckhkgg	277	31	fertility	fertility	NN
cord-287670-z6ckhkgg	277	32	An	an	DT
cord-287670-z6ckhkgg	277	33	acidic	acidic	JJ
cord-287670-z6ckhkgg	277	34	microenvironment	microenvironment	NN
cord-287670-z6ckhkgg	277	35	sets	set	VBZ
cord-287670-z6ckhkgg	277	36	the	the	DT
cord-287670-z6ckhkgg	277	37	humoral	humoral	JJ
cord-287670-z6ckhkgg	277	38	pattern	pattern	NN
cord-287670-z6ckhkgg	277	39	recognition	recognition	NN
cord-287670-z6ckhkgg	277	40	molecule	molecule	NN
cord-287670-z6ckhkgg	277	41	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	277	42	in	in	IN
cord-287670-z6ckhkgg	277	43	a	a	DT
cord-287670-z6ckhkgg	277	44	tissue	tissue	NN
cord-287670-z6ckhkgg	277	45	repair	repair	NN
cord-287670-z6ckhkgg	277	46	mode	mode	NN
cord-287670-z6ckhkgg	277	47	The	the	DT
cord-287670-z6ckhkgg	277	48	humoral	humoral	JJ
cord-287670-z6ckhkgg	277	49	pattern	pattern	NN
cord-287670-z6ckhkgg	277	50	recognition	recognition	NN
cord-287670-z6ckhkgg	277	51	receptor	receptor	NN
cord-287670-z6ckhkgg	277	52	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	277	53	is	be	VBZ
cord-287670-z6ckhkgg	277	54	stored	store	VBN
cord-287670-z6ckhkgg	277	55	in	in	IN
cord-287670-z6ckhkgg	277	56	neutrophil	neutrophil	NN
cord-287670-z6ckhkgg	277	57	granules	granule	NNS
cord-287670-z6ckhkgg	277	58	and	and	CC
cord-287670-z6ckhkgg	277	59	localizes	localize	VBZ
cord-287670-z6ckhkgg	277	60	in	in	IN
cord-287670-z6ckhkgg	277	61	extracellular	extracellular	JJ
cord-287670-z6ckhkgg	277	62	traps	trap	NNS
cord-287670-z6ckhkgg	278	1	C	C	NNP
cord-287670-z6ckhkgg	278	2	-	-	HYPH
cord-287670-z6ckhkgg	278	3	reactive	reactive	JJ
cord-287670-z6ckhkgg	278	4	protein	protein	NN
cord-287670-z6ckhkgg	278	5	and	and	CC
cord-287670-z6ckhkgg	278	6	coronary	coronary	JJ
cord-287670-z6ckhkgg	278	7	heart	heart	NN
cord-287670-z6ckhkgg	278	8	disease	disease	NN
cord-287670-z6ckhkgg	278	9	:	:	:
cord-287670-z6ckhkgg	278	10	a	a	DT
cord-287670-z6ckhkgg	278	11	critical	critical	JJ
cord-287670-z6ckhkgg	278	12	review	review	NNP
cord-287670-z6ckhkgg	278	13	Association	Association	NNP
cord-287670-z6ckhkgg	278	14	between	between	IN
cord-287670-z6ckhkgg	278	15	C	C	NNP
cord-287670-z6ckhkgg	278	16	reactive	reactive	JJ
cord-287670-z6ckhkgg	278	17	protein	protein	NN
cord-287670-z6ckhkgg	278	18	and	and	CC
cord-287670-z6ckhkgg	278	19	coronary	coronary	JJ
cord-287670-z6ckhkgg	278	20	heart	heart	NN
cord-287670-z6ckhkgg	278	21	disease	disease	NN
cord-287670-z6ckhkgg	278	22	:	:	:
cord-287670-z6ckhkgg	278	23	Mendelian	mendelian	JJ
cord-287670-z6ckhkgg	278	24	randomisation	randomisation	NN
cord-287670-z6ckhkgg	278	25	analysis	analysis	NN
cord-287670-z6ckhkgg	278	26	based	base	VBN
cord-287670-z6ckhkgg	278	27	on	on	IN
cord-287670-z6ckhkgg	278	28	individual	individual	JJ
cord-287670-z6ckhkgg	278	29	participant	participant	NN
cord-287670-z6ckhkgg	278	30	data	datum	NNS
cord-287670-z6ckhkgg	279	1	The	the	DT
cord-287670-z6ckhkgg	279	2	long	long	JJ
cord-287670-z6ckhkgg	279	3	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	279	4	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	279	5	:	:	:
cord-287670-z6ckhkgg	279	6	a	a	DT
cord-287670-z6ckhkgg	279	7	modulator	modulator	NN
cord-287670-z6ckhkgg	279	8	of	of	IN
cord-287670-z6ckhkgg	279	9	the	the	DT
cord-287670-z6ckhkgg	279	10	immunoinflammatory	immunoinflammatory	NNP
cord-287670-z6ckhkgg	279	11	response	response	NN
cord-287670-z6ckhkgg	279	12	in	in	IN
cord-287670-z6ckhkgg	279	13	atherosclerosis	atherosclerosis	NN
cord-287670-z6ckhkgg	279	14	and	and	CC
cord-287670-z6ckhkgg	279	15	cardiovascular	cardiovascular	JJ
cord-287670-z6ckhkgg	279	16	diseases	disease	NNS
cord-287670-z6ckhkgg	280	1	Targeting	target	VBG
cord-287670-z6ckhkgg	280	2	C	c	NN
cord-287670-z6ckhkgg	280	3	-	-	HYPH
cord-287670-z6ckhkgg	280	4	reactive	reactive	JJ
cord-287670-z6ckhkgg	280	5	protein	protein	NN
cord-287670-z6ckhkgg	280	6	for	for	IN
cord-287670-z6ckhkgg	280	7	the	the	DT
cord-287670-z6ckhkgg	280	8	treatment	treatment	NN
cord-287670-z6ckhkgg	280	9	of	of	IN
cord-287670-z6ckhkgg	280	10	cardiovascular	cardiovascular	JJ
cord-287670-z6ckhkgg	280	11	disease	disease	NN
cord-287670-z6ckhkgg	280	12	Transgenic	Transgenic	NNP
cord-287670-z6ckhkgg	280	13	human	human	NN
cord-287670-z6ckhkgg	280	14	C	C	NNP
cord-287670-z6ckhkgg	280	15	-	-	HYPH
cord-287670-z6ckhkgg	280	16	reactive	reactive	JJ
cord-287670-z6ckhkgg	280	17	protein	protein	NN
cord-287670-z6ckhkgg	280	18	is	be	VBZ
cord-287670-z6ckhkgg	280	19	not	not	RB
cord-287670-z6ckhkgg	280	20	proatherogenic	proatherogenic	JJ
cord-287670-z6ckhkgg	280	21	in	in	IN
cord-287670-z6ckhkgg	280	22	apolipoprotein	apolipoprotein	NN
cord-287670-z6ckhkgg	280	23	E	e	NN
cord-287670-z6ckhkgg	280	24	-	-	JJ
cord-287670-z6ckhkgg	280	25	deficient	deficient	JJ
cord-287670-z6ckhkgg	280	26	mice	mouse	NNS
cord-287670-z6ckhkgg	280	27	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	280	28	is	be	VBZ
cord-287670-z6ckhkgg	280	29	an	an	DT
cord-287670-z6ckhkgg	280	30	extrinsic	extrinsic	JJ
cord-287670-z6ckhkgg	280	31	oncosuppressor	oncosuppressor	NN
cord-287670-z6ckhkgg	280	32	regulating	regulate	VBG
cord-287670-z6ckhkgg	280	33	complement	complement	NN
cord-287670-z6ckhkgg	280	34	-	-	HYPH
cord-287670-z6ckhkgg	280	35	dependent	dependent	JJ
cord-287670-z6ckhkgg	280	36	inflammation	inflammation	NN
cord-287670-z6ckhkgg	280	37	in	in	IN
cord-287670-z6ckhkgg	280	38	cancer	cancer	NN
cord-287670-z6ckhkgg	280	39	Recognition	recognition	NN
cord-287670-z6ckhkgg	280	40	of	of	IN
cord-287670-z6ckhkgg	280	41	Neisseria	Neisseria	NNP
cord-287670-z6ckhkgg	280	42	meningitidis	meningitidis	NN
cord-287670-z6ckhkgg	280	43	by	by	IN
cord-287670-z6ckhkgg	280	44	the	the	DT
cord-287670-z6ckhkgg	280	45	long	long	JJ
cord-287670-z6ckhkgg	280	46	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	280	47	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	280	48	and	and	CC
cord-287670-z6ckhkgg	280	49	its	-PRON-	PRP$
cord-287670-z6ckhkgg	280	50	role	role	NN
cord-287670-z6ckhkgg	280	51	as	as	IN
cord-287670-z6ckhkgg	280	52	an	an	DT
cord-287670-z6ckhkgg	280	53	endogenous	endogenous	JJ
cord-287670-z6ckhkgg	280	54	adjuvant	adjuvant	NN
cord-287670-z6ckhkgg	280	55	The	the	DT
cord-287670-z6ckhkgg	280	56	humoral	humoral	JJ
cord-287670-z6ckhkgg	280	57	pattern	pattern	NN
cord-287670-z6ckhkgg	280	58	recognition	recognition	NN
cord-287670-z6ckhkgg	280	59	molecule	molecule	NN
cord-287670-z6ckhkgg	280	60	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	280	61	is	be	VBZ
cord-287670-z6ckhkgg	280	62	a	a	DT
cord-287670-z6ckhkgg	280	63	key	key	JJ
cord-287670-z6ckhkgg	280	64	component	component	NN
cord-287670-z6ckhkgg	280	65	of	of	IN
cord-287670-z6ckhkgg	280	66	innate	innate	JJ
cord-287670-z6ckhkgg	280	67	immunity	immunity	NN
cord-287670-z6ckhkgg	280	68	against	against	IN
cord-287670-z6ckhkgg	280	69	urinary	urinary	JJ
cord-287670-z6ckhkgg	280	70	tract	tract	NN
cord-287670-z6ckhkgg	280	71	infection	infection	NN
cord-287670-z6ckhkgg	280	72	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	280	73	,	,	,
cord-287670-z6ckhkgg	280	74	a	a	DT
cord-287670-z6ckhkgg	280	75	humoral	humoral	JJ
cord-287670-z6ckhkgg	280	76	pattern	pattern	NN
cord-287670-z6ckhkgg	280	77	recognition	recognition	NN
cord-287670-z6ckhkgg	280	78	molecule	molecule	NN
cord-287670-z6ckhkgg	280	79	at	at	IN
cord-287670-z6ckhkgg	280	80	the	the	DT
cord-287670-z6ckhkgg	280	81	interface	interface	NN
cord-287670-z6ckhkgg	280	82	between	between	IN
cord-287670-z6ckhkgg	280	83	microbe	microbe	NN
cord-287670-z6ckhkgg	280	84	and	and	CC
cord-287670-z6ckhkgg	280	85	matrix	matrix	NN
cord-287670-z6ckhkgg	280	86	recognition	recognition	NN
cord-287670-z6ckhkgg	280	87	The	the	DT
cord-287670-z6ckhkgg	280	88	long	long	JJ
cord-287670-z6ckhkgg	280	89	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	280	90	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	280	91	as	as	IN
cord-287670-z6ckhkgg	280	92	a	a	DT
cord-287670-z6ckhkgg	280	93	key	key	JJ
cord-287670-z6ckhkgg	280	94	component	component	NN
cord-287670-z6ckhkgg	280	95	of	of	IN
cord-287670-z6ckhkgg	280	96	humoral	humoral	JJ
cord-287670-z6ckhkgg	280	97	innate	innate	JJ
cord-287670-z6ckhkgg	280	98	immunity	immunity	NN
cord-287670-z6ckhkgg	280	99	and	and	CC
cord-287670-z6ckhkgg	280	100	a	a	DT
cord-287670-z6ckhkgg	280	101	candidate	candidate	NN
cord-287670-z6ckhkgg	280	102	diagnostic	diagnostic	JJ
cord-287670-z6ckhkgg	280	103	for	for	IN
cord-287670-z6ckhkgg	280	104	inflammatory	inflammatory	JJ
cord-287670-z6ckhkgg	280	105	diseases	disease	NNS
cord-287670-z6ckhkgg	281	1	Dual	dual	JJ
cord-287670-z6ckhkgg	281	2	function	function	NN
cord-287670-z6ckhkgg	281	3	of	of	IN
cord-287670-z6ckhkgg	281	4	the	the	DT
cord-287670-z6ckhkgg	281	5	long	long	JJ
cord-287670-z6ckhkgg	281	6	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	281	7	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	281	8	in	in	IN
cord-287670-z6ckhkgg	281	9	resistance	resistance	NN
cord-287670-z6ckhkgg	281	10	against	against	IN
cord-287670-z6ckhkgg	281	11	pulmonary	pulmonary	JJ
cord-287670-z6ckhkgg	281	12	infection	infection	NN
cord-287670-z6ckhkgg	281	13	with	with	IN
cord-287670-z6ckhkgg	281	14	Klebsiella	Klebsiella	NNP
cord-287670-z6ckhkgg	281	15	pneumoniae	pneumoniae	NN
cord-287670-z6ckhkgg	281	16	in	in	IN
cord-287670-z6ckhkgg	281	17	transgenic	transgenic	JJ
cord-287670-z6ckhkgg	281	18	mice	mouse	NNS
cord-287670-z6ckhkgg	282	1	Prognostic	prognostic	JJ
cord-287670-z6ckhkgg	282	2	and	and	CC
cord-287670-z6ckhkgg	282	3	diagnostic	diagnostic	JJ
cord-287670-z6ckhkgg	282	4	potential	potential	NN
cord-287670-z6ckhkgg	282	5	of	of	IN
cord-287670-z6ckhkgg	282	6	local	local	JJ
cord-287670-z6ckhkgg	282	7	and	and	CC
cord-287670-z6ckhkgg	282	8	circulating	circulate	VBG
cord-287670-z6ckhkgg	282	9	levels	level	NNS
cord-287670-z6ckhkgg	282	10	of	of	IN
cord-287670-z6ckhkgg	282	11	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	282	12	3	3	CD
cord-287670-z6ckhkgg	282	13	in	in	IN
cord-287670-z6ckhkgg	282	14	lung	lung	NN
cord-287670-z6ckhkgg	282	15	cancer	cancer	NN
cord-287670-z6ckhkgg	282	16	patients	patient	NNS
cord-287670-z6ckhkgg	282	17	Targeting	target	VBG
cord-287670-z6ckhkgg	282	18	chemotherapy	chemotherapy	NN
cord-287670-z6ckhkgg	282	19	-	-	HYPH
cord-287670-z6ckhkgg	282	20	induced	induce	VBN
cord-287670-z6ckhkgg	282	21	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	282	22	in	in	IN
cord-287670-z6ckhkgg	282	23	tumor	tumor	NN
cord-287670-z6ckhkgg	282	24	stroma	stroma	NN
cord-287670-z6ckhkgg	282	25	to	to	TO
cord-287670-z6ckhkgg	282	26	prevent	prevent	VB
cord-287670-z6ckhkgg	282	27	the	the	DT
cord-287670-z6ckhkgg	282	28	progression	progression	NN
cord-287670-z6ckhkgg	282	29	of	of	IN
cord-287670-z6ckhkgg	282	30	drug	drug	NN
cord-287670-z6ckhkgg	282	31	-	-	HYPH
cord-287670-z6ckhkgg	282	32	resistant	resistant	JJ
cord-287670-z6ckhkgg	282	33	cancers	cancer	NNS
cord-287670-z6ckhkgg	282	34	Structural	structural	JJ
cord-287670-z6ckhkgg	282	35	recognition	recognition	NN
cord-287670-z6ckhkgg	282	36	and	and	CC
cord-287670-z6ckhkgg	282	37	functional	functional	JJ
cord-287670-z6ckhkgg	282	38	activation	activation	NN
cord-287670-z6ckhkgg	282	39	of	of	IN
cord-287670-z6ckhkgg	282	40	FcgR	FcgR	NNP
cord-287670-z6ckhkgg	282	41	by	by	IN
cord-287670-z6ckhkgg	282	42	innate	innate	JJ
cord-287670-z6ckhkgg	282	43	pentraxins	pentraxin	NNS
cord-287670-z6ckhkgg	282	44	Evolution	Evolution	NNP
cord-287670-z6ckhkgg	282	45	of	of	IN
cord-287670-z6ckhkgg	282	46	the	the	DT
cord-287670-z6ckhkgg	282	47	pentraxin	pentraxin	NNP
cord-287670-z6ckhkgg	282	48	family	family	NN
cord-287670-z6ckhkgg	282	49	:	:	:
cord-287670-z6ckhkgg	283	1	the	the	DT
cord-287670-z6ckhkgg	283	2	new	new	JJ
cord-287670-z6ckhkgg	283	3	entry	entry	NN
cord-287670-z6ckhkgg	283	4	PTX4	PTX4	NNP
cord-287670-z6ckhkgg	283	5	Cardioprotective	Cardioprotective	NNP
cord-287670-z6ckhkgg	283	6	function	function	NN
cord-287670-z6ckhkgg	283	7	of	of	IN
cord-287670-z6ckhkgg	283	8	the	the	DT
cord-287670-z6ckhkgg	283	9	long	long	JJ
cord-287670-z6ckhkgg	283	10	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	283	11	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	283	12	in	in	IN
cord-287670-z6ckhkgg	283	13	acute	acute	JJ
cord-287670-z6ckhkgg	283	14	myocardial	myocardial	JJ
cord-287670-z6ckhkgg	283	15	infarction	infarction	NN
cord-287670-z6ckhkgg	283	16	Promoter	Promoter	NNP
cord-287670-z6ckhkgg	283	17	structure	structure	NN
cord-287670-z6ckhkgg	283	18	and	and	CC
cord-287670-z6ckhkgg	283	19	transcriptional	transcriptional	JJ
cord-287670-z6ckhkgg	283	20	activation	activation	NN
cord-287670-z6ckhkgg	283	21	of	of	IN
cord-287670-z6ckhkgg	283	22	the	the	DT
cord-287670-z6ckhkgg	283	23	murine	murine	JJ
cord-287670-z6ckhkgg	283	24	TSG-14	TSG-14	NNP
cord-287670-z6ckhkgg	283	25	gene	gene	NN
cord-287670-z6ckhkgg	283	26	encoding	encoding	NN
cord-287670-z6ckhkgg	284	1	a	a	DT
cord-287670-z6ckhkgg	284	2	tumor	tumor	NN
cord-287670-z6ckhkgg	284	3	necrosis	necrosis	NN
cord-287670-z6ckhkgg	284	4	factor	factor	NN
cord-287670-z6ckhkgg	285	1	/interleukin-1-inducible	/interleukin-1-inducible	.
cord-287670-z6ckhkgg	286	1	pentraxin	pentraxin	NNP
cord-287670-z6ckhkgg	286	2	protein	protein	NNP
cord-287670-z6ckhkgg	286	3	Characterization	Characterization	NNP
cord-287670-z6ckhkgg	286	4	of	of	IN
cord-287670-z6ckhkgg	286	5	the	the	DT
cord-287670-z6ckhkgg	286	6	promoter	promoter	NN
cord-287670-z6ckhkgg	286	7	for	for	IN
cord-287670-z6ckhkgg	286	8	the	the	DT
cord-287670-z6ckhkgg	286	9	human	human	JJ
cord-287670-z6ckhkgg	286	10	long	long	JJ
cord-287670-z6ckhkgg	286	11	pentraxin	pentraxin	NNP
cord-287670-z6ckhkgg	286	12	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	286	13	.	.	.
cord-287670-z6ckhkgg	287	1	Role	role	NN
cord-287670-z6ckhkgg	287	2	of	of	IN
cord-287670-z6ckhkgg	287	3	NF	NF	NNP
cord-287670-z6ckhkgg	287	4	-	-	HYPH
cord-287670-z6ckhkgg	287	5	kB	kB	NNP
cord-287670-z6ckhkgg	287	6	in	in	IN
cord-287670-z6ckhkgg	287	7	tumor	tumor	NN
cord-287670-z6ckhkgg	287	8	necrosis	necrosis	NN
cord-287670-z6ckhkgg	287	9	factor-/	factor-/	.
cord-287670-z6ckhkgg	288	1	and	and	CC
cord-287670-z6ckhkgg	288	2	interleukin-1b	interleukin-1b	NNP
cord-287670-z6ckhkgg	288	3	regulation	regulation	NN
cord-287670-z6ckhkgg	288	4	Structural	structural	JJ
cord-287670-z6ckhkgg	288	5	characterization	characterization	NN
cord-287670-z6ckhkgg	288	6	of	of	IN
cord-287670-z6ckhkgg	288	7	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	288	8	disulfide	disulfide	NN
cord-287670-z6ckhkgg	288	9	bond	bond	NN
cord-287670-z6ckhkgg	288	10	network	network	NN
cord-287670-z6ckhkgg	288	11	and	and	CC
cord-287670-z6ckhkgg	288	12	its	-PRON-	PRP$
cord-287670-z6ckhkgg	288	13	multimeric	multimeric	JJ
cord-287670-z6ckhkgg	288	14	status	status	NN
cord-287670-z6ckhkgg	288	15	in	in	IN
cord-287670-z6ckhkgg	288	16	cumulus	cumulus	NNP
cord-287670-z6ckhkgg	288	17	matrix	matrix	NNP
cord-287670-z6ckhkgg	288	18	organization	organization	NNP
cord-287670-z6ckhkgg	288	19	Structure	Structure	NNP
cord-287670-z6ckhkgg	288	20	and	and	CC
cord-287670-z6ckhkgg	288	21	function	function	NN
cord-287670-z6ckhkgg	288	22	of	of	IN
cord-287670-z6ckhkgg	288	23	the	the	DT
cord-287670-z6ckhkgg	288	24	long	long	JJ
cord-287670-z6ckhkgg	288	25	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	288	26	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	288	27	glycosidic	glycosidic	NNP
cord-287670-z6ckhkgg	288	28	moiety	moiety	NN
cord-287670-z6ckhkgg	288	29	:	:	:
cord-287670-z6ckhkgg	288	30	fine	fine	JJ
cord-287670-z6ckhkgg	288	31	-	-	HYPH
cord-287670-z6ckhkgg	288	32	tuning	tuning	NN
cord-287670-z6ckhkgg	288	33	of	of	IN
cord-287670-z6ckhkgg	288	34	the	the	DT
cord-287670-z6ckhkgg	288	35	interaction	interaction	NN
cord-287670-z6ckhkgg	288	36	with	with	IN
cord-287670-z6ckhkgg	288	37	C1q	C1q	NNP
cord-287670-z6ckhkgg	288	38	and	and	CC
cord-287670-z6ckhkgg	288	39	complement	complement	NN
cord-287670-z6ckhkgg	288	40	activation	activation	NN
cord-287670-z6ckhkgg	288	41	Binding	Binding	NNP
cord-287670-z6ckhkgg	288	42	of	of	IN
cord-287670-z6ckhkgg	288	43	the	the	DT
cord-287670-z6ckhkgg	288	44	long	long	JJ
cord-287670-z6ckhkgg	288	45	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	288	46	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	288	47	to	to	IN
cord-287670-z6ckhkgg	288	48	Factor	factor	NN
cord-287670-z6ckhkgg	288	49	H	H	NNP
cord-287670-z6ckhkgg	288	50	:	:	:
cord-287670-z6ckhkgg	288	51	interacting	interact	VBG
cord-287670-z6ckhkgg	288	52	domains	domain	NNS
cord-287670-z6ckhkgg	288	53	and	and	CC
cord-287670-z6ckhkgg	288	54	function	function	VB
cord-287670-z6ckhkgg	288	55	in	in	IN
cord-287670-z6ckhkgg	288	56	the	the	DT
cord-287670-z6ckhkgg	288	57	regulation	regulation	NN
cord-287670-z6ckhkgg	288	58	of	of	IN
cord-287670-z6ckhkgg	288	59	complement	complement	JJ
cord-287670-z6ckhkgg	288	60	activation	activation	NN
cord-287670-z6ckhkgg	288	61	M	M	NNP
cord-287670-z6ckhkgg	288	62	-	-	HYPH
cord-287670-z6ckhkgg	288	63	ficolin	ficolin	NNP
cord-287670-z6ckhkgg	289	1	interacts	interact	VBZ
cord-287670-z6ckhkgg	289	2	with	with	IN
cord-287670-z6ckhkgg	289	3	the	the	DT
cord-287670-z6ckhkgg	289	4	long	long	JJ
cord-287670-z6ckhkgg	289	5	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	289	6	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	289	7	:	:	:
cord-287670-z6ckhkgg	289	8	a	a	DT
cord-287670-z6ckhkgg	289	9	novel	novel	JJ
cord-287670-z6ckhkgg	289	10	case	case	NN
cord-287670-z6ckhkgg	289	11	of	of	IN
cord-287670-z6ckhkgg	289	12	cross	cross	JJ
cord-287670-z6ckhkgg	289	13	-	-	NN
cord-287670-z6ckhkgg	289	14	talk	talk	NN
cord-287670-z6ckhkgg	289	15	between	between	IN
cord-287670-z6ckhkgg	289	16	soluble	soluble	JJ
cord-287670-z6ckhkgg	289	17	pattern	pattern	NN
cord-287670-z6ckhkgg	289	18	-	-	HYPH
cord-287670-z6ckhkgg	289	19	recognition	recognition	NN
cord-287670-z6ckhkgg	289	20	molecules	molecule	NNS
cord-287670-z6ckhkgg	290	1	Antiviral	antiviral	JJ
cord-287670-z6ckhkgg	290	2	activity	activity	NN
cord-287670-z6ckhkgg	290	3	of	of	IN
cord-287670-z6ckhkgg	290	4	the	the	DT
cord-287670-z6ckhkgg	290	5	long	long	JJ
cord-287670-z6ckhkgg	290	6	chain	chain	NN
cord-287670-z6ckhkgg	290	7	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	290	8	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	290	9	against	against	IN
cord-287670-z6ckhkgg	290	10	influenza	influenza	NN
cord-287670-z6ckhkgg	290	11	viruses	virus	NNS
cord-287670-z6ckhkgg	290	12	Regulation	regulation	NN
cord-287670-z6ckhkgg	290	13	of	of	IN
cord-287670-z6ckhkgg	290	14	leukocyte	leukocyte	NN
cord-287670-z6ckhkgg	290	15	recruitment	recruitment	NN
cord-287670-z6ckhkgg	290	16	by	by	IN
cord-287670-z6ckhkgg	290	17	the	the	DT
cord-287670-z6ckhkgg	290	18	long	long	JJ
cord-287670-z6ckhkgg	290	19	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	290	20	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	290	21	Early	early	JJ
cord-287670-z6ckhkgg	290	22	and	and	CC
cord-287670-z6ckhkgg	290	23	transient	transient	JJ
cord-287670-z6ckhkgg	290	24	release	release	NN
cord-287670-z6ckhkgg	290	25	of	of	IN
cord-287670-z6ckhkgg	290	26	leukocyte	leukocyte	NN
cord-287670-z6ckhkgg	290	27	pentraxin	pentraxin	NNP
cord-287670-z6ckhkgg	290	28	3	3	CD
cord-287670-z6ckhkgg	290	29	during	during	IN
cord-287670-z6ckhkgg	290	30	acute	acute	JJ
cord-287670-z6ckhkgg	290	31	myocardial	myocardial	JJ
cord-287670-z6ckhkgg	290	32	infarction	infarction	NN
cord-287670-z6ckhkgg	290	33	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	290	34	as	as	IN
cord-287670-z6ckhkgg	290	35	a	a	DT
cord-287670-z6ckhkgg	290	36	paradigm	paradigm	NN
cord-287670-z6ckhkgg	290	37	for	for	IN
cord-287670-z6ckhkgg	290	38	the	the	DT
cord-287670-z6ckhkgg	290	39	interaction	interaction	NN
cord-287670-z6ckhkgg	290	40	of	of	IN
cord-287670-z6ckhkgg	290	41	pentraxins	pentraxin	NNS
cord-287670-z6ckhkgg	290	42	with	with	IN
cord-287670-z6ckhkgg	290	43	the	the	DT
cord-287670-z6ckhkgg	290	44	complement	complement	NN
cord-287670-z6ckhkgg	290	45	system	system	NN
cord-287670-z6ckhkgg	290	46	Pentraxins	Pentraxins	NNP
cord-287670-z6ckhkgg	290	47	in	in	IN
cord-287670-z6ckhkgg	290	48	innate	innate	JJ
cord-287670-z6ckhkgg	290	49	immunity	immunity	NN
cord-287670-z6ckhkgg	290	50	:	:	:
cord-287670-z6ckhkgg	290	51	from	from	IN
cord-287670-z6ckhkgg	290	52	Creactive	Creactive	NNP
cord-287670-z6ckhkgg	290	53	protein	protein	NN
cord-287670-z6ckhkgg	290	54	to	to	IN
cord-287670-z6ckhkgg	290	55	the	the	DT
cord-287670-z6ckhkgg	290	56	long	long	JJ
cord-287670-z6ckhkgg	290	57	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	290	58	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	290	59	Circulating	circulate	VBG
cord-287670-z6ckhkgg	290	60	levels	level	NNS
cord-287670-z6ckhkgg	290	61	of	of	IN
cord-287670-z6ckhkgg	290	62	the	the	DT
cord-287670-z6ckhkgg	290	63	long	long	JJ
cord-287670-z6ckhkgg	290	64	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	290	65	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	290	66	correlate	correlate	VBP
cord-287670-z6ckhkgg	290	67	with	with	IN
cord-287670-z6ckhkgg	290	68	severity	severity	NN
cord-287670-z6ckhkgg	290	69	of	of	IN
cord-287670-z6ckhkgg	290	70	infection	infection	NN
cord-287670-z6ckhkgg	290	71	in	in	IN
cord-287670-z6ckhkgg	290	72	critically	critically	RB
cord-287670-z6ckhkgg	290	73	ill	ill	JJ
cord-287670-z6ckhkgg	290	74	patients	patient	NNS
cord-287670-z6ckhkgg	291	1	Long	long	RB
cord-287670-z6ckhkgg	291	2	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	291	3	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	291	4	is	be	VBZ
cord-287670-z6ckhkgg	291	5	associated	associate	VBN
cord-287670-z6ckhkgg	291	6	with	with	IN
cord-287670-z6ckhkgg	291	7	mortality	mortality	NN
cord-287670-z6ckhkgg	291	8	and	and	CC
cord-287670-z6ckhkgg	291	9	disease	disease	NN
cord-287670-z6ckhkgg	291	10	severity	severity	NN
cord-287670-z6ckhkgg	291	11	in	in	IN
cord-287670-z6ckhkgg	291	12	severe	severe	JJ
cord-287670-z6ckhkgg	291	13	leptospirosis	leptospirosis	NN
cord-287670-z6ckhkgg	292	1	Persisting	persist	VBG
cord-287670-z6ckhkgg	292	2	high	high	JJ
cord-287670-z6ckhkgg	292	3	levels	level	NNS
cord-287670-z6ckhkgg	292	4	of	of	IN
cord-287670-z6ckhkgg	292	5	plasma	plasma	NN
cord-287670-z6ckhkgg	292	6	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	292	7	3	3	CD
cord-287670-z6ckhkgg	292	8	over	over	IN
cord-287670-z6ckhkgg	292	9	the	the	DT
cord-287670-z6ckhkgg	292	10	first	first	JJ
cord-287670-z6ckhkgg	292	11	days	day	NNS
cord-287670-z6ckhkgg	292	12	after	after	IN
cord-287670-z6ckhkgg	292	13	severe	severe	JJ
cord-287670-z6ckhkgg	292	14	sepsis	sepsis	NN
cord-287670-z6ckhkgg	292	15	and	and	CC
cord-287670-z6ckhkgg	292	16	septic	septic	JJ
cord-287670-z6ckhkgg	292	17	shock	shock	NN
cord-287670-z6ckhkgg	292	18	onset	onset	NN
cord-287670-z6ckhkgg	292	19	are	be	VBP
cord-287670-z6ckhkgg	292	20	associated	associate	VBN
cord-287670-z6ckhkgg	292	21	with	with	IN
cord-287670-z6ckhkgg	292	22	mortality	mortality	NN
cord-287670-z6ckhkgg	292	23	Non	non	JJ
cord-287670-z6ckhkgg	292	24	-	-	JJ
cord-287670-z6ckhkgg	292	25	redundant	redundant	JJ
cord-287670-z6ckhkgg	292	26	role	role	NN
cord-287670-z6ckhkgg	292	27	of	of	IN
cord-287670-z6ckhkgg	292	28	the	the	DT
cord-287670-z6ckhkgg	292	29	long	long	JJ
cord-287670-z6ckhkgg	292	30	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	292	31	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	292	32	in	in	IN
cord-287670-z6ckhkgg	292	33	anti	anti	JJ
cord-287670-z6ckhkgg	292	34	-	-	JJ
cord-287670-z6ckhkgg	292	35	fungal	fungal	JJ
cord-287670-z6ckhkgg	292	36	innate	innate	JJ
cord-287670-z6ckhkgg	292	37	immune	immune	JJ
cord-287670-z6ckhkgg	292	38	response	response	NN
cord-287670-z6ckhkgg	292	39	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	292	40	function	function	NN
cord-287670-z6ckhkgg	292	41	as	as	IN
cord-287670-z6ckhkgg	292	42	an	an	DT
cord-287670-z6ckhkgg	292	43	opsonin	opsonin	NN
cord-287670-z6ckhkgg	292	44	for	for	IN
cord-287670-z6ckhkgg	292	45	the	the	DT
cord-287670-z6ckhkgg	292	46	Dectin-1-dependent	dectin-1-dependent	JJ
cord-287670-z6ckhkgg	292	47	internalization	internalization	NN
cord-287670-z6ckhkgg	292	48	of	of	IN
cord-287670-z6ckhkgg	292	49	zymosan	zymosan	NNP
cord-287670-z6ckhkgg	292	50	by	by	IN
cord-287670-z6ckhkgg	292	51	macrophages	macrophage	NNS
cord-287670-z6ckhkgg	292	52	Role	role	NN
cord-287670-z6ckhkgg	292	53	of	of	IN
cord-287670-z6ckhkgg	292	54	complement	complement	NN
cord-287670-z6ckhkgg	292	55	and	and	CC
cord-287670-z6ckhkgg	292	56	Fcg	Fcg	NNP
cord-287670-z6ckhkgg	292	57	receptors	receptor	NNS
cord-287670-z6ckhkgg	292	58	in	in	IN
cord-287670-z6ckhkgg	292	59	the	the	DT
cord-287670-z6ckhkgg	292	60	protective	protective	JJ
cord-287670-z6ckhkgg	292	61	activity	activity	NN
cord-287670-z6ckhkgg	292	62	of	of	IN
cord-287670-z6ckhkgg	292	63	the	the	DT
cord-287670-z6ckhkgg	292	64	long	long	JJ
cord-287670-z6ckhkgg	292	65	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	292	66	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	292	67	against	against	IN
cord-287670-z6ckhkgg	292	68	Aspergillus	aspergillus	NN
cord-287670-z6ckhkgg	292	69	fumigatus	fumigatus	NN
cord-287670-z6ckhkgg	292	70	Anti	anti	JJ
cord-287670-z6ckhkgg	292	71	-	-	JJ
cord-287670-z6ckhkgg	292	72	Aspergillus	aspergillus	JJ
cord-287670-z6ckhkgg	292	73	fumigatus	fumigatus	NN
cord-287670-z6ckhkgg	292	74	efficacy	efficacy	NN
cord-287670-z6ckhkgg	292	75	of	of	IN
cord-287670-z6ckhkgg	292	76	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	292	77	3	3	CD
cord-287670-z6ckhkgg	292	78	alone	alone	RB
cord-287670-z6ckhkgg	292	79	and	and	CC
cord-287670-z6ckhkgg	292	80	in	in	IN
cord-287670-z6ckhkgg	292	81	combination	combination	NN
cord-287670-z6ckhkgg	292	82	with	with	IN
cord-287670-z6ckhkgg	292	83	antifungals	antifungal	NNS
cord-287670-z6ckhkgg	292	84	Synergy	Synergy	NNP
cord-287670-z6ckhkgg	292	85	between	between	IN
cord-287670-z6ckhkgg	292	86	ficolin-2	ficolin-2	NNP
cord-287670-z6ckhkgg	292	87	and	and	CC
cord-287670-z6ckhkgg	292	88	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	292	89	3	3	CD
cord-287670-z6ckhkgg	292	90	boosts	boost	VBZ
cord-287670-z6ckhkgg	292	91	innate	innate	JJ
cord-287670-z6ckhkgg	292	92	immune	immune	JJ
cord-287670-z6ckhkgg	292	93	recognition	recognition	NN
cord-287670-z6ckhkgg	292	94	and	and	CC
cord-287670-z6ckhkgg	292	95	complement	complement	NN
cord-287670-z6ckhkgg	292	96	deposition	deposition	NN
cord-287670-z6ckhkgg	292	97	Ficolin-1-PTX3	Ficolin-1-PTX3	NNP
cord-287670-z6ckhkgg	292	98	complex	complex	JJ
cord-287670-z6ckhkgg	292	99	formation	formation	NN
cord-287670-z6ckhkgg	292	100	promotes	promote	VBZ
cord-287670-z6ckhkgg	292	101	clearance	clearance	NN
cord-287670-z6ckhkgg	292	102	of	of	IN
cord-287670-z6ckhkgg	292	103	altered	altered	JJ
cord-287670-z6ckhkgg	292	104	self	self	NN
cord-287670-z6ckhkgg	292	105	-	-	HYPH
cord-287670-z6ckhkgg	292	106	cells	cell	NNS
cord-287670-z6ckhkgg	292	107	and	and	CC
cord-287670-z6ckhkgg	292	108	modulates	modulate	VBZ
cord-287670-z6ckhkgg	292	109	IL-8	il-8	NN
cord-287670-z6ckhkgg	292	110	production	production	NN
cord-287670-z6ckhkgg	292	111	Genetic	Genetic	NNP
cord-287670-z6ckhkgg	292	112	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	292	113	deficiency	deficiency	NN
cord-287670-z6ckhkgg	292	114	and	and	CC
cord-287670-z6ckhkgg	292	115	aspergillosis	aspergillosis	NN
cord-287670-z6ckhkgg	292	116	in	in	IN
cord-287670-z6ckhkgg	292	117	stem	stem	NN
cord-287670-z6ckhkgg	292	118	-	-	HYPH
cord-287670-z6ckhkgg	292	119	cell	cell	NN
cord-287670-z6ckhkgg	292	120	transplantation	transplantation	NN
cord-287670-z6ckhkgg	292	121	Polymorphisms	polymorphism	NNS
cord-287670-z6ckhkgg	292	122	and	and	CC
cord-287670-z6ckhkgg	292	123	invasive	invasive	JJ
cord-287670-z6ckhkgg	292	124	mold	mold	NN
cord-287670-z6ckhkgg	292	125	infections	infection	NNS
cord-287670-z6ckhkgg	292	126	after	after	IN
cord-287670-z6ckhkgg	292	127	solid	solid	JJ
cord-287670-z6ckhkgg	292	128	organ	organ	NN
cord-287670-z6ckhkgg	292	129	transplant	transplant	NN
cord-287670-z6ckhkgg	293	1	PTX3-based	ptx3-based	JJ
cord-287670-z6ckhkgg	293	2	genetic	genetic	JJ
cord-287670-z6ckhkgg	293	3	testing	testing	NN
cord-287670-z6ckhkgg	293	4	for	for	IN
cord-287670-z6ckhkgg	293	5	risk	risk	NN
cord-287670-z6ckhkgg	293	6	of	of	IN
cord-287670-z6ckhkgg	293	7	Aspergillosis	Aspergillosis	NNP
cord-287670-z6ckhkgg	293	8	after	after	IN
cord-287670-z6ckhkgg	293	9	lung	lung	NN
cord-287670-z6ckhkgg	293	10	transplant	transplant	NN
cord-287670-z6ckhkgg	293	11	Complexity	complexity	NN
cord-287670-z6ckhkgg	293	12	and	and	CC
cord-287670-z6ckhkgg	293	13	complementarity	complementarity	NN
cord-287670-z6ckhkgg	293	14	of	of	IN
cord-287670-z6ckhkgg	293	15	outer	outer	JJ
cord-287670-z6ckhkgg	293	16	membrane	membrane	NN
cord-287670-z6ckhkgg	293	17	protein	protein	NN
cord-287670-z6ckhkgg	293	18	A	a	DT
cord-287670-z6ckhkgg	293	19	recognition	recognition	NN
cord-287670-z6ckhkgg	293	20	by	by	IN
cord-287670-z6ckhkgg	293	21	cellular	cellular	JJ
cord-287670-z6ckhkgg	293	22	and	and	CC
cord-287670-z6ckhkgg	293	23	humoral	humoral	JJ
cord-287670-z6ckhkgg	293	24	innate	innate	JJ
cord-287670-z6ckhkgg	293	25	immunity	immunity	NN
cord-287670-z6ckhkgg	293	26	receptors	receptor	NNS
cord-287670-z6ckhkgg	294	1	The	the	DT
cord-287670-z6ckhkgg	294	2	therapeutic	therapeutic	JJ
cord-287670-z6ckhkgg	294	3	potential	potential	NN
cord-287670-z6ckhkgg	294	4	of	of	IN
cord-287670-z6ckhkgg	294	5	the	the	DT
cord-287670-z6ckhkgg	294	6	humoral	humoral	JJ
cord-287670-z6ckhkgg	294	7	pattern	pattern	NN
cord-287670-z6ckhkgg	294	8	recognition	recognition	NN
cord-287670-z6ckhkgg	294	9	molecule	molecule	NN
cord-287670-z6ckhkgg	294	10	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	294	11	in	in	IN
cord-287670-z6ckhkgg	294	12	chronic	chronic	JJ
cord-287670-z6ckhkgg	294	13	lung	lung	NN
cord-287670-z6ckhkgg	294	14	infection	infection	NN
cord-287670-z6ckhkgg	294	15	caused	cause	VBN
cord-287670-z6ckhkgg	294	16	by	by	IN
cord-287670-z6ckhkgg	294	17	Pseudomonas	Pseudomonas	NNP
cord-287670-z6ckhkgg	294	18	aeruginosa	aeruginosa	VBZ
cord-287670-z6ckhkgg	294	19	Prototypic	Prototypic	NNP
cord-287670-z6ckhkgg	294	20	long	long	RB
cord-287670-z6ckhkgg	294	21	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	294	22	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	294	23	is	be	VBZ
cord-287670-z6ckhkgg	294	24	present	present	JJ
cord-287670-z6ckhkgg	294	25	in	in	IN
cord-287670-z6ckhkgg	294	26	breast	breast	NN
cord-287670-z6ckhkgg	294	27	milk	milk	NN
cord-287670-z6ckhkgg	294	28	,	,	,
cord-287670-z6ckhkgg	294	29	spreads	spread	VBZ
cord-287670-z6ckhkgg	294	30	in	in	IN
cord-287670-z6ckhkgg	294	31	tissues	tissue	NNS
cord-287670-z6ckhkgg	294	32	,	,	,
cord-287670-z6ckhkgg	294	33	and	and	CC
cord-287670-z6ckhkgg	294	34	protects	protect	VBZ
cord-287670-z6ckhkgg	294	35	neonate	neonate	NN
cord-287670-z6ckhkgg	294	36	mice	mouse	NNS
cord-287670-z6ckhkgg	294	37	from	from	IN
cord-287670-z6ckhkgg	294	38	Pseudomonas	Pseudomonas	NNP
cord-287670-z6ckhkgg	294	39	aeruginosa	aeruginosa	NN
cord-287670-z6ckhkgg	294	40	lung	lung	NN
cord-287670-z6ckhkgg	294	41	infection	infection	NN
cord-287670-z6ckhkgg	294	42	DC	DC	NNP
cord-287670-z6ckhkgg	294	43	-	-	HYPH
cord-287670-z6ckhkgg	294	44	SIGN	sign	NN
cord-287670-z6ckhkgg	294	45	(	(	-LRB-
cord-287670-z6ckhkgg	294	46	CD209	CD209	NNP
cord-287670-z6ckhkgg	294	47	)	)	-RRB-
cord-287670-z6ckhkgg	294	48	,	,	,
cord-287670-z6ckhkgg	294	49	pentraxin	pentraxin	NNP
cord-287670-z6ckhkgg	294	50	3	3	CD
cord-287670-z6ckhkgg	294	51	and	and	CC
cord-287670-z6ckhkgg	294	52	vitamin	vitamin	NN
cord-287670-z6ckhkgg	294	53	D	D	NNP
cord-287670-z6ckhkgg	294	54	receptor	receptor	NN
cord-287670-z6ckhkgg	294	55	gene	gene	NN
cord-287670-z6ckhkgg	294	56	variants	variant	NNS
cord-287670-z6ckhkgg	294	57	associate	associate	VBP
cord-287670-z6ckhkgg	294	58	with	with	IN
cord-287670-z6ckhkgg	294	59	pulmonary	pulmonary	JJ
cord-287670-z6ckhkgg	294	60	tuberculosis	tuberculosis	NN
cord-287670-z6ckhkgg	294	61	risk	risk	NN
cord-287670-z6ckhkgg	294	62	in	in	IN
cord-287670-z6ckhkgg	294	63	West	West	NNP
cord-287670-z6ckhkgg	294	64	Africans	Africans	NNPS
cord-287670-z6ckhkgg	294	65	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	295	1	interacts	interact	VBZ
cord-287670-z6ckhkgg	295	2	with	with	IN
cord-287670-z6ckhkgg	295	3	inter-/-trypsin	inter-/-trypsin	CD
cord-287670-z6ckhkgg	295	4	inhibitor	inhibitor	NN
cord-287670-z6ckhkgg	296	1	:	:	:
cord-287670-z6ckhkgg	296	2	implications	implication	NNS
cord-287670-z6ckhkgg	296	3	for	for	IN
cord-287670-z6ckhkgg	296	4	hyaluronan	hyaluronan	NNP
cord-287670-z6ckhkgg	296	5	organization	organization	NNP
cord-287670-z6ckhkgg	296	6	and	and	CC
cord-287670-z6ckhkgg	296	7	cumulus	cumulus	NNP
cord-287670-z6ckhkgg	296	8	oophorus	oophorus	NNP
cord-287670-z6ckhkgg	296	9	expansion	expansion	NN
cord-287670-z6ckhkgg	296	10	Identification	Identification	NNP
cord-287670-z6ckhkgg	296	11	of	of	IN
cord-287670-z6ckhkgg	296	12	an	an	DT
cord-287670-z6ckhkgg	296	13	antiangiogenic	antiangiogenic	JJ
cord-287670-z6ckhkgg	296	14	FGF2-binding	fgf2-binding	NN
cord-287670-z6ckhkgg	296	15	site	site	NN
cord-287670-z6ckhkgg	296	16	in	in	IN
cord-287670-z6ckhkgg	296	17	the	the	DT
cord-287670-z6ckhkgg	296	18	N	n	CD
cord-287670-z6ckhkgg	296	19	terminus	terminus	NN
cord-287670-z6ckhkgg	296	20	of	of	IN
cord-287670-z6ckhkgg	296	21	the	the	DT
cord-287670-z6ckhkgg	296	22	soluble	soluble	JJ
cord-287670-z6ckhkgg	296	23	pattern	pattern	NN
cord-287670-z6ckhkgg	296	24	recognition	recognition	NN
cord-287670-z6ckhkgg	296	25	receptor	receptor	NN
cord-287670-z6ckhkgg	296	26	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	296	27	Role	Role	NNP
cord-287670-z6ckhkgg	296	28	of	of	IN
cord-287670-z6ckhkgg	296	29	the	the	DT
cord-287670-z6ckhkgg	296	30	soluble	soluble	JJ
cord-287670-z6ckhkgg	296	31	pattern	pattern	NN
cord-287670-z6ckhkgg	296	32	recognition	recognition	NN
cord-287670-z6ckhkgg	296	33	receptor	receptor	NN
cord-287670-z6ckhkgg	296	34	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	296	35	in	in	IN
cord-287670-z6ckhkgg	296	36	vascular	vascular	JJ
cord-287670-z6ckhkgg	296	37	biology	biology	NN
cord-287670-z6ckhkgg	296	38	Long	Long	NNP
cord-287670-z6ckhkgg	296	39	pentraxin-3	pentraxin-3	NNP
cord-287670-z6ckhkgg	296	40	as	as	IN
cord-287670-z6ckhkgg	296	41	an	an	DT
cord-287670-z6ckhkgg	296	42	epithelial	epithelial	JJ
cord-287670-z6ckhkgg	296	43	-	-	HYPH
cord-287670-z6ckhkgg	296	44	stromal	stromal	JJ
cord-287670-z6ckhkgg	296	45	fibroblast	fibroblast	NN
cord-287670-z6ckhkgg	296	46	growth	growth	NN
cord-287670-z6ckhkgg	296	47	factor	factor	NN
cord-287670-z6ckhkgg	296	48	-	-	HYPH
cord-287670-z6ckhkgg	296	49	targeting	target	VBG
cord-287670-z6ckhkgg	296	50	inhibitor	inhibitor	NN
cord-287670-z6ckhkgg	296	51	in	in	IN
cord-287670-z6ckhkgg	296	52	prostate	prostate	NN
cord-287670-z6ckhkgg	296	53	cancer	cancer	NN
cord-287670-z6ckhkgg	296	54	Selective	selective	JJ
cord-287670-z6ckhkgg	296	55	recognition	recognition	NN
cord-287670-z6ckhkgg	296	56	of	of	IN
cord-287670-z6ckhkgg	296	57	fibroblast	fibroblast	NN
cord-287670-z6ckhkgg	296	58	growth	growth	NN
cord-287670-z6ckhkgg	296	59	factor-2	factor-2	JJ
cord-287670-z6ckhkgg	296	60	by	by	IN
cord-287670-z6ckhkgg	296	61	the	the	DT
cord-287670-z6ckhkgg	296	62	long	long	JJ
cord-287670-z6ckhkgg	296	63	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	296	64	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	296	65	inhibits	inhibit	VBZ
cord-287670-z6ckhkgg	296	66	angiogenesis	angiogenesis	NN
cord-287670-z6ckhkgg	297	1	Pentraxin	Pentraxin	NNP
cord-287670-z6ckhkgg	297	2	3	3	CD
cord-287670-z6ckhkgg	297	3	inhibits	inhibit	VBZ
cord-287670-z6ckhkgg	298	1	fibroblast	fibroblast	NN
cord-287670-z6ckhkgg	298	2	growth	growth	NN
cord-287670-z6ckhkgg	298	3	factor	factor	NN
cord-287670-z6ckhkgg	298	4	2-dependent	2-dependent	CD
cord-287670-z6ckhkgg	298	5	activation	activation	NN
cord-287670-z6ckhkgg	298	6	of	of	IN
cord-287670-z6ckhkgg	298	7	smooth	smooth	JJ
cord-287670-z6ckhkgg	298	8	muscle	muscle	NN
cord-287670-z6ckhkgg	298	9	cells	cell	NNS
cord-287670-z6ckhkgg	298	10	in	in	IN
cord-287670-z6ckhkgg	298	11	vitro	vitro	FW
cord-287670-z6ckhkgg	298	12	and	and	CC
cord-287670-z6ckhkgg	298	13	neointima	neointima	NNP
cord-287670-z6ckhkgg	298	14	formation	formation	NN
cord-287670-z6ckhkgg	298	15	in	in	IN
cord-287670-z6ckhkgg	298	16	vivo	vivo	NNP
cord-287670-z6ckhkgg	298	17	Fibroblast	Fibroblast	NNP
cord-287670-z6ckhkgg	298	18	growth	growth	NN
cord-287670-z6ckhkgg	298	19	factor-2	factor-2	JJ
cord-287670-z6ckhkgg	298	20	antagonist	antagonist	NN
cord-287670-z6ckhkgg	298	21	and	and	CC
cord-287670-z6ckhkgg	298	22	antiangiogenic	antiangiogenic	JJ
cord-287670-z6ckhkgg	298	23	activity	activity	NN
cord-287670-z6ckhkgg	298	24	of	of	IN
cord-287670-z6ckhkgg	298	25	long	long	JJ
cord-287670-z6ckhkgg	298	26	-	-	HYPH
cord-287670-z6ckhkgg	298	27	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	298	28	3-derived	3-derived	CD
cord-287670-z6ckhkgg	298	29	synthetic	synthetic	JJ
cord-287670-z6ckhkgg	298	30	peptides	peptide	NNS
cord-287670-z6ckhkgg	298	31	Anti	Anti	NNP
cord-287670-z6ckhkgg	298	32	-	-	JJ
cord-287670-z6ckhkgg	298	33	FGF2	fgf2	JJ
cord-287670-z6ckhkgg	298	34	approaches	approach	NNS
cord-287670-z6ckhkgg	298	35	as	as	IN
cord-287670-z6ckhkgg	298	36	a	a	DT
cord-287670-z6ckhkgg	298	37	strategy	strategy	NN
cord-287670-z6ckhkgg	298	38	to	to	TO
cord-287670-z6ckhkgg	298	39	compensate	compensate	VB
cord-287670-z6ckhkgg	298	40	resistance	resistance	NN
cord-287670-z6ckhkgg	298	41	to	to	IN
cord-287670-z6ckhkgg	298	42	anti	anti	JJ
cord-287670-z6ckhkgg	298	43	-	-	JJ
cord-287670-z6ckhkgg	298	44	VEGF	vegf	JJ
cord-287670-z6ckhkgg	298	45	therapy	therapy	NN
cord-287670-z6ckhkgg	298	46	:	:	:
cord-287670-z6ckhkgg	298	47	long	long	RB
cord-287670-z6ckhkgg	298	48	-	-	HYPH
cord-287670-z6ckhkgg	298	49	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	298	50	3	3	CD
cord-287670-z6ckhkgg	298	51	as	as	IN
cord-287670-z6ckhkgg	298	52	a	a	DT
cord-287670-z6ckhkgg	298	53	novel	novel	NN
cord-287670-z6ckhkgg	298	54	antiangiogenic	antiangiogenic	NNP
cord-287670-z6ckhkgg	298	55	FGF2-antagonist	FGF2-antagonist	NNP
cord-287670-z6ckhkgg	298	56	Deficiency	Deficiency	NNP
cord-287670-z6ckhkgg	298	57	of	of	IN
cord-287670-z6ckhkgg	298	58	the	the	DT
cord-287670-z6ckhkgg	298	59	long	long	JJ
cord-287670-z6ckhkgg	298	60	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	298	61	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	298	62	promotes	promote	VBZ
cord-287670-z6ckhkgg	298	63	vascular	vascular	JJ
cord-287670-z6ckhkgg	298	64	inflammation	inflammation	NN
cord-287670-z6ckhkgg	298	65	and	and	CC
cord-287670-z6ckhkgg	299	1	atherosclerosis	atherosclerosis	NN
cord-287670-z6ckhkgg	299	2	Endogenous	endogenous	JJ
cord-287670-z6ckhkgg	299	3	and	and	CC
cord-287670-z6ckhkgg	299	4	exogenous	exogenous	JJ
cord-287670-z6ckhkgg	299	5	pentraxin-3	pentraxin-3	NNP
cord-287670-z6ckhkgg	299	6	limits	limit	VBZ
cord-287670-z6ckhkgg	299	7	postischemic	postischemic	JJ
cord-287670-z6ckhkgg	299	8	acute	acute	JJ
cord-287670-z6ckhkgg	299	9	and	and	CC
cord-287670-z6ckhkgg	299	10	chronic	chronic	JJ
cord-287670-z6ckhkgg	299	11	kidney	kidney	NN
cord-287670-z6ckhkgg	299	12	injury	injury	NN
cord-287670-z6ckhkgg	299	13	Loss	loss	NN
cord-287670-z6ckhkgg	299	14	of	of	IN
cord-287670-z6ckhkgg	299	15	fibrinogen	fibrinogen	NN
cord-287670-z6ckhkgg	299	16	rescues	rescue	VBZ
cord-287670-z6ckhkgg	299	17	mice	mouse	NNS
cord-287670-z6ckhkgg	299	18	from	from	IN
cord-287670-z6ckhkgg	299	19	the	the	DT
cord-287670-z6ckhkgg	299	20	pleiotropic	pleiotropic	JJ
cord-287670-z6ckhkgg	299	21	effects	effect	NNS
cord-287670-z6ckhkgg	299	22	of	of	IN
cord-287670-z6ckhkgg	299	23	plasminogen	plasminogen	NN
cord-287670-z6ckhkgg	299	24	deficiency	deficiency	NN
cord-287670-z6ckhkgg	299	25	Mesenchymal	Mesenchymal	NNP
cord-287670-z6ckhkgg	299	26	stromal	stromal	JJ
cord-287670-z6ckhkgg	299	27	cell	cell	NN
cord-287670-z6ckhkgg	299	28	-	-	HYPH
cord-287670-z6ckhkgg	299	29	derived	derive	VBN
cord-287670-z6ckhkgg	299	30	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	299	31	promotes	promote	VBZ
cord-287670-z6ckhkgg	299	32	wound	wound	VBP
cord-287670-z6ckhkgg	299	33	healing	healing	NN
cord-287670-z6ckhkgg	299	34	via	via	IN
cord-287670-z6ckhkgg	299	35	fibrin	fibrin	NN
cord-287670-z6ckhkgg	299	36	remodeling	remodeling	NN
cord-287670-z6ckhkgg	299	37	The	the	DT
cord-287670-z6ckhkgg	299	38	primary	primary	JJ
cord-287670-z6ckhkgg	299	39	role	role	NN
cord-287670-z6ckhkgg	299	40	of	of	IN
cord-287670-z6ckhkgg	299	41	fibrinogen	fibrinogen	NN
cord-287670-z6ckhkgg	299	42	-	-	HYPH
cord-287670-z6ckhkgg	299	43	related	relate	VBN
cord-287670-z6ckhkgg	299	44	proteins	protein	NNS
cord-287670-z6ckhkgg	299	45	in	in	IN
cord-287670-z6ckhkgg	299	46	invertebrates	invertebrate	NNS
cord-287670-z6ckhkgg	299	47	is	be	VBZ
cord-287670-z6ckhkgg	299	48	defense	defense	NN
cord-287670-z6ckhkgg	299	49	,	,	,
cord-287670-z6ckhkgg	299	50	not	not	RB
cord-287670-z6ckhkgg	299	51	coagulation	coagulation	NN
cord-287670-z6ckhkgg	300	1	The	the	DT
cord-287670-z6ckhkgg	300	2	immunoproteasome	immunoproteasome	NNP
cord-287670-z6ckhkgg	300	3	controls	control	VBZ
cord-287670-z6ckhkgg	300	4	the	the	DT
cord-287670-z6ckhkgg	300	5	availability	availability	NN
cord-287670-z6ckhkgg	300	6	of	of	IN
cord-287670-z6ckhkgg	300	7	the	the	DT
cord-287670-z6ckhkgg	300	8	cardioprotective	cardioprotective	JJ
cord-287670-z6ckhkgg	300	9	pattern	pattern	NN
cord-287670-z6ckhkgg	300	10	recognition	recognition	NN
cord-287670-z6ckhkgg	300	11	molecule	molecule	NN
cord-287670-z6ckhkgg	300	12	pentraxin3	pentraxin3	NN
cord-287670-z6ckhkgg	300	13	Dynamic	dynamic	JJ
cord-287670-z6ckhkgg	300	14	induction	induction	NN
cord-287670-z6ckhkgg	300	15	of	of	IN
cord-287670-z6ckhkgg	300	16	the	the	DT
cord-287670-z6ckhkgg	300	17	long	long	JJ
cord-287670-z6ckhkgg	300	18	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	300	19	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	300	20	in	in	IN
cord-287670-z6ckhkgg	300	21	the	the	DT
cord-287670-z6ckhkgg	300	22	CNS	CNS	NNP
cord-287670-z6ckhkgg	300	23	after	after	IN
cord-287670-z6ckhkgg	300	24	limbic	limbic	JJ
cord-287670-z6ckhkgg	300	25	seizures	seizure	NNS
cord-287670-z6ckhkgg	300	26	:	:	:
cord-287670-z6ckhkgg	300	27	evidence	evidence	NN
cord-287670-z6ckhkgg	300	28	for	for	IN
cord-287670-z6ckhkgg	300	29	a	a	DT
cord-287670-z6ckhkgg	300	30	protective	protective	JJ
cord-287670-z6ckhkgg	300	31	role	role	NN
cord-287670-z6ckhkgg	300	32	in	in	IN
cord-287670-z6ckhkgg	300	33	seizure	seizure	NN
cord-287670-z6ckhkgg	300	34	-	-	HYPH
cord-287670-z6ckhkgg	300	35	induced	induce	VBN
cord-287670-z6ckhkgg	300	36	neurodegeneration	neurodegeneration	NN
cord-287670-z6ckhkgg	301	1	The	the	DT
cord-287670-z6ckhkgg	301	2	acute	acute	JJ
cord-287670-z6ckhkgg	301	3	-	-	HYPH
cord-287670-z6ckhkgg	301	4	phase	phase	NN
cord-287670-z6ckhkgg	301	5	protein	protein	NN
cord-287670-z6ckhkgg	301	6	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	301	7	is	be	VBZ
cord-287670-z6ckhkgg	301	8	an	an	DT
cord-287670-z6ckhkgg	301	9	essential	essential	JJ
cord-287670-z6ckhkgg	301	10	mediator	mediator	NN
cord-287670-z6ckhkgg	301	11	of	of	IN
cord-287670-z6ckhkgg	301	12	glial	glial	JJ
cord-287670-z6ckhkgg	301	13	scar	scar	NN
cord-287670-z6ckhkgg	301	14	formation	formation	NN
cord-287670-z6ckhkgg	301	15	and	and	CC
cord-287670-z6ckhkgg	301	16	resolution	resolution	NN
cord-287670-z6ckhkgg	301	17	of	of	IN
cord-287670-z6ckhkgg	301	18	brain	brain	NN
cord-287670-z6ckhkgg	301	19	edema	edema	NN
cord-287670-z6ckhkgg	301	20	after	after	IN
cord-287670-z6ckhkgg	301	21	ischemic	ischemic	JJ
cord-287670-z6ckhkgg	301	22	injury	injury	NN
cord-287670-z6ckhkgg	302	1	Pentraxin	Pentraxin	NNP
cord-287670-z6ckhkgg	302	2	3	3	CD
cord-287670-z6ckhkgg	302	3	mediates	mediate	VBZ
cord-287670-z6ckhkgg	302	4	neurogenesis	neurogenesis	NN
cord-287670-z6ckhkgg	302	5	and	and	CC
cord-287670-z6ckhkgg	302	6	angiogenesis	angiogenesis	NN
cord-287670-z6ckhkgg	302	7	after	after	IN
cord-287670-z6ckhkgg	302	8	cerebral	cerebral	JJ
cord-287670-z6ckhkgg	302	9	ischaemia	ischaemia	NN
cord-287670-z6ckhkgg	302	10	Astrocyte	Astrocyte	NNP
cord-287670-z6ckhkgg	302	11	-	-	HYPH
cord-287670-z6ckhkgg	302	12	derived	derive	VBN
cord-287670-z6ckhkgg	302	13	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	302	14	3	3	CD
cord-287670-z6ckhkgg	302	15	supports	support	VBZ
cord-287670-z6ckhkgg	302	16	blood	blood	NN
cord-287670-z6ckhkgg	302	17	-	-	HYPH
cord-287670-z6ckhkgg	302	18	brain	brain	NN
cord-287670-z6ckhkgg	302	19	barrier	barrier	NN
cord-287670-z6ckhkgg	302	20	integrity	integrity	NN
cord-287670-z6ckhkgg	302	21	under	under	IN
cord-287670-z6ckhkgg	302	22	acute	acute	JJ
cord-287670-z6ckhkgg	302	23	phase	phase	NN
cord-287670-z6ckhkgg	302	24	of	of	IN
cord-287670-z6ckhkgg	302	25	stroke	stroke	NN
cord-287670-z6ckhkgg	303	1	The	the	DT
cord-287670-z6ckhkgg	303	2	long	long	JJ
cord-287670-z6ckhkgg	303	3	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	303	4	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	303	5	is	be	VBZ
cord-287670-z6ckhkgg	303	6	crucial	crucial	JJ
cord-287670-z6ckhkgg	303	7	for	for	IN
cord-287670-z6ckhkgg	303	8	tissue	tissue	NN
cord-287670-z6ckhkgg	303	9	inflammation	inflammation	NN
cord-287670-z6ckhkgg	303	10	after	after	IN
cord-287670-z6ckhkgg	303	11	intestinal	intestinal	JJ
cord-287670-z6ckhkgg	303	12	ischemia	ischemia	NN
cord-287670-z6ckhkgg	303	13	and	and	CC
cord-287670-z6ckhkgg	303	14	reperfusion	reperfusion	NN
cord-287670-z6ckhkgg	303	15	in	in	IN
cord-287670-z6ckhkgg	303	16	mice	mouse	NNS
cord-287670-z6ckhkgg	303	17	Increased	increase	VBD
cord-287670-z6ckhkgg	303	18	mortality	mortality	NN
cord-287670-z6ckhkgg	303	19	and	and	CC
cord-287670-z6ckhkgg	303	20	inflammation	inflammation	NN
cord-287670-z6ckhkgg	303	21	in	in	IN
cord-287670-z6ckhkgg	303	22	tumor	tumor	NN
cord-287670-z6ckhkgg	303	23	necrosis	necrosis	NN
cord-287670-z6ckhkgg	303	24	factor	factor	NN
cord-287670-z6ckhkgg	303	25	-	-	HYPH
cord-287670-z6ckhkgg	303	26	stimulated	stimulate	VBN
cord-287670-z6ckhkgg	303	27	gene-14	gene-14	CD
cord-287670-z6ckhkgg	303	28	transgenic	transgenic	JJ
cord-287670-z6ckhkgg	303	29	mice	mouse	NNS
cord-287670-z6ckhkgg	303	30	after	after	IN
cord-287670-z6ckhkgg	303	31	ischemia	ischemia	NN
cord-287670-z6ckhkgg	303	32	and	and	CC
cord-287670-z6ckhkgg	303	33	reperfusion	reperfusion	NN
cord-287670-z6ckhkgg	303	34	injury	injury	NN
cord-287670-z6ckhkgg	304	1	Pentraxin	Pentraxin	NNP
cord-287670-z6ckhkgg	304	2	3	3	CD
cord-287670-z6ckhkgg	304	3	accelerates	accelerate	VBZ
cord-287670-z6ckhkgg	304	4	lung	lung	NN
cord-287670-z6ckhkgg	304	5	injury	injury	NN
cord-287670-z6ckhkgg	304	6	in	in	IN
cord-287670-z6ckhkgg	304	7	high	high	JJ
cord-287670-z6ckhkgg	304	8	tidal	tidal	JJ
cord-287670-z6ckhkgg	304	9	volume	volume	NN
cord-287670-z6ckhkgg	304	10	ventilation	ventilation	NN
cord-287670-z6ckhkgg	304	11	in	in	IN
cord-287670-z6ckhkgg	304	12	mice	mouse	NNS
cord-287670-z6ckhkgg	305	1	Long	long	RB
cord-287670-z6ckhkgg	305	2	pentraxin	pentraxin	NNP
cord-287670-z6ckhkgg	305	3	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	305	4	exacerbates	exacerbate	VBZ
cord-287670-z6ckhkgg	305	5	pressure	pressure	NN
cord-287670-z6ckhkgg	305	6	overload	overload	NN
cord-287670-z6ckhkgg	305	7	-	-	HYPH
cord-287670-z6ckhkgg	305	8	induced	induce	VBN
cord-287670-z6ckhkgg	305	9	left	leave	VBN
cord-287670-z6ckhkgg	305	10	ventricular	ventricular	JJ
cord-287670-z6ckhkgg	305	11	dysfunction	dysfunction	NN
cord-287670-z6ckhkgg	306	1	Pentraxin	Pentraxin	NNP
cord-287670-z6ckhkgg	306	2	3	3	CD
cord-287670-z6ckhkgg	306	3	induces	induce	VBZ
cord-287670-z6ckhkgg	306	4	vascular	vascular	JJ
cord-287670-z6ckhkgg	306	5	endothelial	endothelial	JJ
cord-287670-z6ckhkgg	306	6	dysfunction	dysfunction	NN
cord-287670-z6ckhkgg	306	7	through	through	IN
cord-287670-z6ckhkgg	306	8	a	a	DT
cord-287670-z6ckhkgg	306	9	P	p	NN
cord-287670-z6ckhkgg	306	10	-	-	HYPH
cord-287670-z6ckhkgg	306	11	selectin	selectin	NN
cord-287670-z6ckhkgg	306	12	/	/	SYM
cord-287670-z6ckhkgg	306	13	matrix	matrix	NN
cord-287670-z6ckhkgg	306	14	metalloproteinase-1	metalloproteinase-1	NNP
cord-287670-z6ckhkgg	306	15	pathway	pathway	NN
cord-287670-z6ckhkgg	306	16	Cancer	cancer	NN
cord-287670-z6ckhkgg	306	17	-	-	HYPH
cord-287670-z6ckhkgg	306	18	related	relate	VBN
cord-287670-z6ckhkgg	306	19	inflammation	inflammation	NN
cord-287670-z6ckhkgg	306	20	C	c	NN
cord-287670-z6ckhkgg	306	21	-	-	HYPH
cord-287670-z6ckhkgg	306	22	reactive	reactive	JJ
cord-287670-z6ckhkgg	306	23	protein	protein	NN
cord-287670-z6ckhkgg	306	24	and	and	CC
cord-287670-z6ckhkgg	306	25	risk	risk	NN
cord-287670-z6ckhkgg	306	26	of	of	IN
cord-287670-z6ckhkgg	306	27	breast	breast	NN
cord-287670-z6ckhkgg	306	28	cancer	cancer	NN
cord-287670-z6ckhkgg	306	29	:	:	:
cord-287670-z6ckhkgg	307	1	a	a	DT
cord-287670-z6ckhkgg	307	2	systematic	systematic	JJ
cord-287670-z6ckhkgg	307	3	review	review	NN
cord-287670-z6ckhkgg	307	4	and	and	CC
cord-287670-z6ckhkgg	307	5	meta	meta	NNP
cord-287670-z6ckhkgg	307	6	-	-	HYPH
cord-287670-z6ckhkgg	307	7	analysis	analysis	NN
cord-287670-z6ckhkgg	307	8	Clinical	clinical	JJ
cord-287670-z6ckhkgg	307	9	impact	impact	NN
cord-287670-z6ckhkgg	307	10	of	of	IN
cord-287670-z6ckhkgg	307	11	pentraxin	pentraxin	NNP
cord-287670-z6ckhkgg	307	12	family	family	NN
cord-287670-z6ckhkgg	307	13	expression	expression	NN
cord-287670-z6ckhkgg	307	14	on	on	IN
cord-287670-z6ckhkgg	307	15	prognosis	prognosis	NN
cord-287670-z6ckhkgg	307	16	of	of	IN
cord-287670-z6ckhkgg	307	17	pancreatic	pancreatic	JJ
cord-287670-z6ckhkgg	307	18	carcinoma	carcinoma	NN
cord-287670-z6ckhkgg	307	19	Construction	construction	NN
cord-287670-z6ckhkgg	307	20	and	and	CC
cord-287670-z6ckhkgg	307	21	validation	validation	NN
cord-287670-z6ckhkgg	307	22	of	of	IN
cord-287670-z6ckhkgg	307	23	a	a	DT
cord-287670-z6ckhkgg	307	24	prognostic	prognostic	JJ
cord-287670-z6ckhkgg	307	25	index	index	NN
cord-287670-z6ckhkgg	307	26	for	for	IN
cord-287670-z6ckhkgg	307	27	patients	patient	NNS
cord-287670-z6ckhkgg	307	28	with	with	IN
cord-287670-z6ckhkgg	307	29	metastatic	metastatic	JJ
cord-287670-z6ckhkgg	307	30	pancreatic	pancreatic	JJ
cord-287670-z6ckhkgg	307	31	adenocarcinoma	adenocarcinoma	NN
cord-287670-z6ckhkgg	307	32	Elevated	elevate	VBN
cord-287670-z6ckhkgg	307	33	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	307	34	3	3	CD
cord-287670-z6ckhkgg	307	35	in	in	IN
cord-287670-z6ckhkgg	307	36	bone	bone	NN
cord-287670-z6ckhkgg	307	37	metastatic	metastatic	JJ
cord-287670-z6ckhkgg	307	38	breast	breast	NN
cord-287670-z6ckhkgg	307	39	cancer	cancer	NN
cord-287670-z6ckhkgg	307	40	is	be	VBZ
cord-287670-z6ckhkgg	307	41	correlated	correlate	VBN
cord-287670-z6ckhkgg	307	42	with	with	IN
cord-287670-z6ckhkgg	307	43	osteolytic	osteolytic	JJ
cord-287670-z6ckhkgg	307	44	function	function	NN
cord-287670-z6ckhkgg	307	45	Pentraxin-3	Pentraxin-3	NNP
cord-287670-z6ckhkgg	307	46	is	be	VBZ
cord-287670-z6ckhkgg	307	47	a	a	DT
cord-287670-z6ckhkgg	307	48	novel	novel	JJ
cord-287670-z6ckhkgg	307	49	biomarker	biomarker	NN
cord-287670-z6ckhkgg	307	50	of	of	IN
cord-287670-z6ckhkgg	307	51	lung	lung	NN
cord-287670-z6ckhkgg	307	52	carcinoma	carcinoma	NN
cord-287670-z6ckhkgg	307	53	Antitumor	Antitumor	NNP
cord-287670-z6ckhkgg	307	54	and	and	CC
cord-287670-z6ckhkgg	307	55	anti	anti	JJ
cord-287670-z6ckhkgg	307	56	-	-	JJ
cord-287670-z6ckhkgg	307	57	inflammatory	inflammatory	JJ
cord-287670-z6ckhkgg	307	58	effects	effect	NNS
cord-287670-z6ckhkgg	307	59	of	of	IN
cord-287670-z6ckhkgg	307	60	trabectedin	trabectedin	NNS
cord-287670-z6ckhkgg	307	61	on	on	IN
cord-287670-z6ckhkgg	307	62	human	human	JJ
cord-287670-z6ckhkgg	307	63	myxoid	myxoid	NNP
cord-287670-z6ckhkgg	307	64	liposarcoma	liposarcoma	NNP
cord-287670-z6ckhkgg	307	65	cells	cell	NNS
cord-287670-z6ckhkgg	308	1	The	the	DT
cord-287670-z6ckhkgg	308	2	long	long	JJ
cord-287670-z6ckhkgg	308	3	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	308	4	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	308	5	as	as	IN
cord-287670-z6ckhkgg	308	6	a	a	DT
cord-287670-z6ckhkgg	308	7	correlate	correlate	NN
cord-287670-z6ckhkgg	308	8	of	of	IN
cord-287670-z6ckhkgg	308	9	cancer	cancer	NN
cord-287670-z6ckhkgg	308	10	-	-	HYPH
cord-287670-z6ckhkgg	308	11	related	relate	VBN
cord-287670-z6ckhkgg	308	12	inflammation	inflammation	NN
cord-287670-z6ckhkgg	308	13	and	and	CC
cord-287670-z6ckhkgg	308	14	prognosis	prognosis	NN
cord-287670-z6ckhkgg	308	15	of	of	IN
cord-287670-z6ckhkgg	308	16	malignancy	malignancy	NN
cord-287670-z6ckhkgg	308	17	in	in	IN
cord-287670-z6ckhkgg	308	18	gliomas	gliomas	NN
cord-287670-z6ckhkgg	309	1	Pentraxin	Pentraxin	NNP
cord-287670-z6ckhkgg	309	2	3	3	CD
cord-287670-z6ckhkgg	309	3	:	:	:
cord-287670-z6ckhkgg	309	4	a	a	DT
cord-287670-z6ckhkgg	309	5	novel	novel	NN
cord-287670-z6ckhkgg	309	6	biomarker	biomarker	NN
cord-287670-z6ckhkgg	309	7	for	for	IN
cord-287670-z6ckhkgg	309	8	predicting	predict	VBG
cord-287670-z6ckhkgg	309	9	progression	progression	NN
cord-287670-z6ckhkgg	309	10	from	from	IN
cord-287670-z6ckhkgg	309	11	prostatic	prostatic	JJ
cord-287670-z6ckhkgg	309	12	inflammation	inflammation	NN
cord-287670-z6ckhkgg	309	13	to	to	IN
cord-287670-z6ckhkgg	309	14	prostate	prostate	NN
cord-287670-z6ckhkgg	309	15	cancer	cancer	NN
cord-287670-z6ckhkgg	309	16	Novel	Novel	NNP
cord-287670-z6ckhkgg	309	17	molecular	molecular	JJ
cord-287670-z6ckhkgg	309	18	subtypes	subtype	NNS
cord-287670-z6ckhkgg	309	19	of	of	IN
cord-287670-z6ckhkgg	309	20	serous	serous	JJ
cord-287670-z6ckhkgg	309	21	and	and	CC
cord-287670-z6ckhkgg	309	22	endometrioid	endometrioid	JJ
cord-287670-z6ckhkgg	309	23	ovarian	ovarian	JJ
cord-287670-z6ckhkgg	309	24	cancer	cancer	NN
cord-287670-z6ckhkgg	309	25	linked	link	VBN
cord-287670-z6ckhkgg	309	26	to	to	IN
cord-287670-z6ckhkgg	309	27	clinical	clinical	JJ
cord-287670-z6ckhkgg	309	28	outcome	outcome	NN
cord-287670-z6ckhkgg	309	29	Genetic	genetic	JJ
cord-287670-z6ckhkgg	309	30	variation	variation	NN
cord-287670-z6ckhkgg	309	31	in	in	IN
cord-287670-z6ckhkgg	309	32	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	309	33	and	and	CC
cord-287670-z6ckhkgg	309	34	plasma	plasma	NN
cord-287670-z6ckhkgg	309	35	levels	level	NNS
cord-287670-z6ckhkgg	309	36	associated	associate	VBN
cord-287670-z6ckhkgg	309	37	with	with	IN
cord-287670-z6ckhkgg	309	38	hepatocellular	hepatocellular	JJ
cord-287670-z6ckhkgg	309	39	carcinoma	carcinoma	NN
cord-287670-z6ckhkgg	309	40	in	in	IN
cord-287670-z6ckhkgg	309	41	patients	patient	NNS
cord-287670-z6ckhkgg	309	42	with	with	IN
cord-287670-z6ckhkgg	309	43	HCV	HCV	NNP
cord-287670-z6ckhkgg	309	44	Cancer	Cancer	NNP
cord-287670-z6ckhkgg	309	45	-	-	HYPH
cord-287670-z6ckhkgg	309	46	related	relate	VBN
cord-287670-z6ckhkgg	309	47	inflammation	inflammation	NN
cord-287670-z6ckhkgg	309	48	,	,	,
cord-287670-z6ckhkgg	309	49	the	the	DT
cord-287670-z6ckhkgg	309	50	seventh	seventh	JJ
cord-287670-z6ckhkgg	309	51	hallmark	hallmark	NN
cord-287670-z6ckhkgg	309	52	of	of	IN
cord-287670-z6ckhkgg	309	53	cancer	cancer	NN
cord-287670-z6ckhkgg	309	54	:	:	:
cord-287670-z6ckhkgg	310	1	links	link	NNS
cord-287670-z6ckhkgg	310	2	to	to	IN
cord-287670-z6ckhkgg	310	3	genetic	genetic	JJ
cord-287670-z6ckhkgg	310	4	instability	instability	NN
cord-287670-z6ckhkgg	310	5	Complement	Complement	NNP
cord-287670-z6ckhkgg	310	6	activation	activation	NN
cord-287670-z6ckhkgg	310	7	promotes	promote	VBZ
cord-287670-z6ckhkgg	310	8	colitisassociated	colitisassociated	JJ
cord-287670-z6ckhkgg	310	9	carcinogenesis	carcinogenesis	NN
cord-287670-z6ckhkgg	310	10	through	through	IN
cord-287670-z6ckhkgg	310	11	activating	activate	VBG
cord-287670-z6ckhkgg	310	12	intestinal	intestinal	JJ
cord-287670-z6ckhkgg	310	13	IL-1b	IL-1b	NNS
cord-287670-z6ckhkgg	310	14	/	/	SYM
cord-287670-z6ckhkgg	310	15	IL-17A	IL-17A	NNP
cord-287670-z6ckhkgg	310	16	axis	axis	NN
cord-287670-z6ckhkgg	310	17	FcRg	FcRg	NNP
cord-287670-z6ckhkgg	310	18	activation	activation	NN
cord-287670-z6ckhkgg	310	19	regulates	regulate	VBZ
cord-287670-z6ckhkgg	310	20	inflammationassociated	inflammationassociate	VBN
cord-287670-z6ckhkgg	310	21	squamous	squamous	JJ
cord-287670-z6ckhkgg	310	22	carcinogenesis	carcinogenesis	NN
cord-287670-z6ckhkgg	311	1	Early	early	JJ
cord-287670-z6ckhkgg	311	2	neoplastic	neoplastic	JJ
cord-287670-z6ckhkgg	311	3	progression	progression	NN
cord-287670-z6ckhkgg	311	4	is	be	VBZ
cord-287670-z6ckhkgg	311	5	complement	complement	VB
cord-287670-z6ckhkgg	311	6	independent	independent	JJ
cord-287670-z6ckhkgg	311	7	Aberrant	aberrant	JJ
cord-287670-z6ckhkgg	311	8	methylation	methylation	NN
cord-287670-z6ckhkgg	311	9	of	of	IN
cord-287670-z6ckhkgg	311	10	the	the	DT
cord-287670-z6ckhkgg	311	11	3q25	3q25	CD
cord-287670-z6ckhkgg	311	12	tumor	tumor	NN
cord-287670-z6ckhkgg	311	13	suppressor	suppressor	NN
cord-287670-z6ckhkgg	311	14	gene	gene	NN
cord-287670-z6ckhkgg	311	15	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	311	16	in	in	IN
cord-287670-z6ckhkgg	311	17	human	human	JJ
cord-287670-z6ckhkgg	311	18	esophageal	esophageal	JJ
cord-287670-z6ckhkgg	311	19	squamous	squamous	JJ
cord-287670-z6ckhkgg	311	20	cell	cell	NN
cord-287670-z6ckhkgg	311	21	carcinoma	carcinoma	NN
cord-287670-z6ckhkgg	311	22	Long	long	JJ
cord-287670-z6ckhkgg	311	23	-	-	HYPH
cord-287670-z6ckhkgg	311	24	pentraxin	pentraxin	NN
cord-287670-z6ckhkgg	311	25	3	3	CD
cord-287670-z6ckhkgg	311	26	derivative	derivative	JJ
cord-287670-z6ckhkgg	311	27	as	as	IN
cord-287670-z6ckhkgg	311	28	a	a	DT
cord-287670-z6ckhkgg	311	29	smallmolecule	smallmolecule	JJ
cord-287670-z6ckhkgg	311	30	FGF	FGF	NNP
cord-287670-z6ckhkgg	311	31	trap	trap	NN
cord-287670-z6ckhkgg	311	32	for	for	IN
cord-287670-z6ckhkgg	311	33	cancer	cancer	NN
cord-287670-z6ckhkgg	311	34	therapy	therapy	NN
cord-287670-z6ckhkgg	311	35	PTX3	PTX3	NNP
cord-287670-z6ckhkgg	311	36	gene	gene	NN
cord-287670-z6ckhkgg	311	37	activation	activation	NN
cord-287670-z6ckhkgg	311	38	in	in	IN
cord-287670-z6ckhkgg	311	39	EGF	EGF	NNP
cord-287670-z6ckhkgg	311	40	-	-	HYPH
cord-287670-z6ckhkgg	311	41	induced	induce	VBN
cord-287670-z6ckhkgg	311	42	head	head	NN
cord-287670-z6ckhkgg	311	43	and	and	CC
cord-287670-z6ckhkgg	311	44	neck	neck	NN
cord-287670-z6ckhkgg	311	45	cancer	cancer	NN
cord-287670-z6ckhkgg	311	46	cell	cell	NN
cord-287670-z6ckhkgg	311	47	metastasis	metastasis	NN
cord-287670-z6ckhkgg	312	1	Pentraxin-3	pentraxin-3	NN
cord-287670-z6ckhkgg	313	1	silencing	silence	VBG
cord-287670-z6ckhkgg	313	2	suppresses	suppress	VBZ
cord-287670-z6ckhkgg	313	3	gastric	gastric	JJ
cord-287670-z6ckhkgg	313	4	cancer	cancer	NN
cord-287670-z6ckhkgg	313	5	-	-	HYPH
cord-287670-z6ckhkgg	313	6	related	relate	VBN
cord-287670-z6ckhkgg	313	7	inflammation	inflammation	NN
cord-287670-z6ckhkgg	313	8	by	by	IN
cord-287670-z6ckhkgg	313	9	inhibiting	inhibit	VBG
cord-287670-z6ckhkgg	313	10	chemotactic	chemotactic	JJ
cord-287670-z6ckhkgg	313	11	migration	migration	NN
cord-287670-z6ckhkgg	313	12	of	of	IN
cord-287670-z6ckhkgg	313	13	macrophages	macrophage	NNS