id author title date pages extension mime words sentences flesch summary cache txt cord-348091-pnvn0x4q Nolte, Thomas Nonproliferative and Proliferative Lesions of the Gastrointestinal Tract, Pancreas and Salivary Glands of the Rat and Mouse 2016-02-13 .txt text/plain 47176 3688 40 Synonym: Cell death Pathogenesis: Unregulated, energy independent, passive cell death with leakage of cytoplasm into surrounding tissue and subsequent inflammatory reaction (single cell necrosis) and/ or gene regulated, energy dependent process leading to formation of apoptotic bodies which are phagocytosed by adjacent cells (apoptosis); typically associated with cytotoxic chemotherapeutics that affect the mucosal epithelium of the tongue, esophagus and/or pharynx. In addition to the proliferative lesions of squamous cell origin, neoplasms of the bone, tooth, or adjacent soft tissues (malignant schwannoma, Zymbal's gland tumor) may extend into the oral cavity and be associated with a gross observation at this location. Synonym: Cell death Pathogenesis: Unregulated, energy independent, passive cell death with leakage of cytoplasm into surrounding tissue and subsequent inflammatory reaction (single cell necrosis) AND/OR gene regulated, energy dependent process leading to formation of apoptotic bodies which are phagocytosed by adjacent cells (apoptosis); typically associated with cytotoxic chemotherapeutics that affect the mucosal epithelium of the nonglandular stomach. ./cache/cord-348091-pnvn0x4q.txt ./txt/cord-348091-pnvn0x4q.txt