id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-032975-7hugs419	SUN, J. D.	Two-Week, Repeated Inhalation Exposure of F344/N Rats and B6C3F Mice to Ferrocene(1)	1991-07-17		.txt	text/plain	3900	199	46	Nasal lesions were observed in all ferrocene-exposed animals and differed only in severity, which was dependent on the exposure concentration. In vitro metabolism studies of ferrocene showed that nasal tissue, particularly the olfactory epithelium, had 10 times higher "ferrocene hydroxylating" activity than did liver tissue from the same animals. Relative to control mice, male rats exposed to the highest concentration of ferrocene (40 mg/m 3 ) had statistically significant decreases in terminal body weight and rate of weight gain during the exposures. Male rats exposed to the highest concentration of ferrocene vapor had a statistically significant, although small, decrease in liver weights, compared to control animals. Similar nasal lesions were found in rats exposed to ferrocene vapor. We did not observe sex-related differences, and the severity of the lesion occurring after exposure to a given ferrocene concentration was about the same in rats and mice.	./cache/cord-032975-7hugs419.txt	./txt/cord-032975-7hugs419.txt