id author title date pages extension mime words sentences flesch summary cache txt cord-010278-loey5xq9 Huh, Changgoo Structural organization, expression and chromosomal mapping of the mouse cystatin-C-encoding gene (Cst3) 1995-01-23 .txt text/plain 2835 170 62 The structure of the mouse CstC-encoding gene (Cst3) was examined by sequencing a 6.1-kb genomic DNA containing the entire gene, as well as 0.9 kb of 5′ flanking and 1.7 kb of its 3′ flanking region. An exact match of nine nt with the pituitary transcription factor (Pit-l) recognition element is centered around nt -795 from the start codon, but is probably of low significance for the expression of the gene because multiple recognition elements have been shown to be needed for markedly increased expression of the rat prolactin gene by Pit-1 (Ingraham et al., 1988 recognized by the leader binding protein (LBP-1), 5'-WCTGG-3' or its inverse, that is present in several copies in the HIV-1 promoter and contribute to its basal function (Jones et al., 1988) , is strikingly abundant in the 5'-flanking region of the mouse Cst3 gene. The presence of the two AP-l-like binding sites in the promoter indicates that Differences between the mouse Cst3 gene sequence and that of the published eDNA (Solem et al., 1990) Position" ./cache/cord-010278-loey5xq9.txt ./txt/cord-010278-loey5xq9.txt