id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-003389-0yh5k6jk	Patton, John B.	Development of Onchocerca volvulus in humanized NSG mice and detection of parasite biomarkers in urine and serum	2018-12-12		.txt	text/plain	7953	400	51	title: Development of Onchocerca volvulus in humanized NSG mice and detection of parasite biomarkers in urine and serum volvulus specific biomarkers, screening for new therapeutic approaches and potentially studying the human immune response to infection with O. Based on the hypothesis that there is a genetic basis for mouse susceptibility and resistance to infection, novel strains of CC mice have been identified that are susceptible to specific bacteria, viruses, and parasites of humans [18] [19] [20] [21] [22] [23] . volvulus larvae after developing in NSG mice with or without human cells was in the same order of magnitude as that reported for the recovery of adult filarial worms, where infections were initiated by larvae recovered directly from the insect vector. Infected HuSkMc mice or BLT mice were selected for this analysis so the biomarkers identified would develop in the presence of human cells thereby potentially enhancing their specificity.	./cache/cord-003389-0yh5k6jk.txt	./txt/cord-003389-0yh5k6jk.txt