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Jessica E.; Rasoanomenjanahary, Anjarasoa title: Long-term trends in seasonality of mortality in urban Madagascar: the role of the epidemiological transition date: 2020-02-06 journal: Glob Health Action DOI: 10.1080/16549716.2020.1717411 sha: doc_id: 298201 cord_uid: z68j0c63 file: cache/cord-015651-yhi83hgq.json key: cord-015651-yhi83hgq authors: Kovács, Katalin title: Social Disparities in the Evolution of an Epidemiological Profile: Transition Processes in Mortality Between 1971 and 2008 in an Industrialized Middle Income Country: The Case of Hungary date: 2014-03-25 journal: Mortality in an International Perspective DOI: 10.1007/978-3-319-03029-6_4 sha: doc_id: 15651 cord_uid: yhi83hgq file: cache/cord-337098-33yj5g5v.json key: cord-337098-33yj5g5v authors: Agarwal, Shivani; Schechter, Clyde; Southern, Will; Crandall, Jill P.; Tomer, Yaron title: Preadmission Diabetes-Specific Risk Factors for Mortality in Hospitalized Patients With Diabetes and Coronavirus Disease 2019 date: 2020-08-07 journal: Diabetes Care DOI: 10.2337/dc20-1543 sha: doc_id: 337098 cord_uid: 33yj5g5v file: cache/cord-337692-b89ow1mf.json key: cord-337692-b89ow1mf authors: Petti, S.; Cowling, B. J. title: Ecologic association between influenza and COVID-19 mortality rates in European countries date: 2020-09-11 journal: Epidemiol Infect DOI: 10.1017/s0950268820002125 sha: doc_id: 337692 cord_uid: b89ow1mf file: cache/cord-353895-tgn1kk07.json key: cord-353895-tgn1kk07 authors: Kavanagh, Matthew M; Katz, Ingrid T; Holmes, Charles B title: Reckoning with mortality: global health, HIV, and the politics of data date: 2020-07-03 journal: Lancet DOI: 10.1016/s0140-6736(20)31046-1 sha: doc_id: 353895 cord_uid: tgn1kk07 file: cache/cord-018834-4ligp4ak.json key: cord-018834-4ligp4ak authors: Farag, Ehab; Ebrahim, Zeyd Y. title: The Perioperative Use of Albumin date: 2016-06-23 journal: Perioperative Fluid Management DOI: 10.1007/978-3-319-39141-0_9 sha: doc_id: 18834 cord_uid: 4ligp4ak file: cache/cord-294645-yzh8h7zo.json key: cord-294645-yzh8h7zo authors: Freeman, David W.; Noren Hooten, Nicole; Kim, Yoonseo; Mode, Nicolle A.; Ejiogu, Ngozi; Zonderman, Alan B.; Evans, Michele K. title: Association between GDF15, poverty and mortality in urban middle-aged African American and white adults date: 2020-08-07 journal: PLoS One DOI: 10.1371/journal.pone.0237059 sha: doc_id: 294645 cord_uid: yzh8h7zo file: cache/cord-000522-d498qj2b.json key: cord-000522-d498qj2b authors: Vincent, Jean-Louis; Abraham, Edward; Annane, Djillali; Bernard, Gordon; Rivers, Emanuel; Van den Berghe, Greet title: Reducing mortality in sepsis: new directions date: 2002-12-05 journal: Crit Care DOI: 10.1186/cc1860 sha: doc_id: 522 cord_uid: d498qj2b file: cache/cord-015126-cyhcbk1j.json key: cord-015126-cyhcbk1j authors: nan title: PS 0036-0344 date: 2007-08-25 journal: Intensive Care Med DOI: 10.1007/s00134-007-0820-y sha: doc_id: 15126 cord_uid: cyhcbk1j file: cache/cord-306205-l42w2jyk.json key: cord-306205-l42w2jyk authors: Ransome, Yusuf title: Is investing in religious institutions a viable pathway to reduce mortality in the population? date: 2020-06-08 journal: Soc Sci Med DOI: 10.1016/j.socscimed.2020.113106 sha: doc_id: 306205 cord_uid: l42w2jyk file: cache/cord-015082-l629n8is.json key: cord-015082-l629n8is authors: nan title: Poster Sessions 323-461 date: 2002-08-29 journal: Intensive Care Med DOI: 10.1007/s00134-002-1455-7 sha: doc_id: 15082 cord_uid: l629n8is file: cache/cord-027259-f4sgobcz.json key: cord-027259-f4sgobcz authors: Metsker, Oleg; Igor, Vozniuk; Kopanitsa, Georgy; Morozova, Elena; Maria, Prohorova title: Stroke ICU Patient Mortality Day Prediction date: 2020-05-23 journal: Computational Science - ICCS 2020 DOI: 10.1007/978-3-030-50423-6_29 sha: doc_id: 27259 cord_uid: f4sgobcz file: cache/cord-293861-n6733nfd.json key: cord-293861-n6733nfd authors: Juhász, Attila; Nagy, Csilla; Varga, Orsolya; Boruzs, Klára; Csernoch, Mária; Szabó, Zoltán; Ádány, Róza title: Antithrombotic Preventive Medication Prescription Redemption and Socioeconomic Status in Hungary in 2016: A Cross-Sectional Study date: 2020-09-19 journal: Int J Environ Res Public Health DOI: 10.3390/ijerph17186855 sha: doc_id: 293861 cord_uid: n6733nfd file: cache/cord-003340-nqc1pduk.json key: cord-003340-nqc1pduk authors: Dahal, Sushma; Mizumoto, Kenji; Bolin, Bob; Viboud, Cécile; Chowell, Gerardo title: Natality Decline and Spatial Variation in Excess Death Rates During the 1918–1920 Influenza Pandemic in Arizona, United States date: 2018-07-26 journal: Am J Epidemiol DOI: 10.1093/aje/kwy146 sha: doc_id: 3340 cord_uid: nqc1pduk file: cache/cord-290295-gl144dh9.json key: cord-290295-gl144dh9 authors: Martínez-López, Joaquín; Mateos, María-Victoria; Encinas, Cristina; Sureda, Anna; Hernández-Rivas, José Ángel; Lopez de la Guía, Ana; Conde, Diego; Krsnik, Isabel; Prieto, Elena; Riaza Grau, Rosalía; Gironella, Mercedes; Blanchard, María Jesús; Caminos, Nerea; Fernández de Larrea, Carlos; Senin, María Alicia; Escalante, Fernando; de la Puerta, José Enrique; Giménez, Eugenio; Martínez-Barranco, Pilar; Mateos, Juan José; Casado, Luis Felipe; Bladé, Joan; Lahuerta, Juan José; de la Cruz, Javier; San-Miguel, Jesús title: Multiple myeloma and SARS-CoV-2 infection: clinical characteristics and prognostic factors of inpatient mortality date: 2020-10-19 journal: Blood Cancer J DOI: 10.1038/s41408-020-00372-5 sha: doc_id: 290295 cord_uid: gl144dh9 file: cache/cord-284332-p4c1fneh.json key: cord-284332-p4c1fneh authors: Bosma, Karen J.; Taneja, Ravi; Lewis, James F. title: Pharmacotherapy for Prevention and Treatment of Acute Respiratory Distress Syndrome: Current and Experimental Approaches date: 2012-09-19 journal: Drugs DOI: 10.2165/10898570-000000000-00000 sha: doc_id: 284332 cord_uid: p4c1fneh file: cache/cord-273283-gb0m6fue.json key: cord-273283-gb0m6fue authors: Altschul, David J.; Unda, Santiago R.; Benton, Joshua; de la Garza Ramos, Rafael; Cezayirli, Phillip; Mehler, Mark; Eskandar, Emad N. title: A novel severity score to predict inpatient mortality in COVID-19 patients date: 2020-10-07 journal: Sci Rep DOI: 10.1038/s41598-020-73962-9 sha: doc_id: 273283 cord_uid: gb0m6fue file: cache/cord-269777-dm6te7nw.json key: cord-269777-dm6te7nw authors: Vukina, T; Barnes, HJ; Solakoglu, MN title: Intervention decision model to prevent spiking mortality of turkeys date: 1998-07-01 journal: Poultry Science DOI: 10.1093/ps/77.7.950 sha: doc_id: 269777 cord_uid: dm6te7nw file: cache/cord-014538-6a2pviol.json key: cord-014538-6a2pviol authors: Kamilia, Chtara; Regaieg, Kais; Baccouch, Najeh; Chelly, Hedi; Bahloul, Mabrouk; Bouaziz, Mounir; Jendoubi, Ali; Abbes, Ahmed; Belhaouane, Houda; Nasri, Oussama; Jenzri, Layla; Ghedira, Salma; Houissa, Mohamed; Belkadi, Kamal; Harti, Youness; Nsiri, Afak; Khaleq, Khalid; Hamoudi, Driss; Harrar, Rachid; Thieffry, Camille; Wallet, Frédéric; 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Ghadhoune, Hatem; Chaari, Anis; Jihene, Guissouma; Allouche, Hend; Trabelsi, Insaf; Brahmi, Habib; Samet, Mohamed; Ghord, Hatem El; Habiba, Ben Sik Ali; Hajer, Nouira; Tilouch, Najla; Yaakoubi, Sondes; Jaoued, Oussama; Gharbi, Rim; Hassen, Mohamed Fekih; Elatrous, Souheil; Arcizet, Julien; Leroy, Bertrand; Abdulmalack, Caroline; Renzullo, Catherine; Hamet, Maël; Doise, Jean-Marc; Coutet, Jérôme; Cheikh, Chaigar Mohammed; Quechar, Zakaria; Joris, Magalie; Beauport, Dimitri Titeca; Kontar, Loay; Lebon, Delphine; Gruson, Bérengère; Slama, Michel; Marolleau, Jean-Pierre; Maizel, Julien; Gorham, Julie; Ameye, Lieveke; Berghmans, Thierry; Paesmans, Marianne; Sculier, Jean-Paul; Meert, Anne-Pascale; Guillot, Max; Ledoux, Marie-Pierre; Braun, Thierry; Maestraggi, Quentin; Michard, Baptiste; Castelain, Vincent; Herbrecht, Raoul; Schneider, Francis; Couffin, Severine; Lobo, David; Mongardon, Nicolas; Dhonneur, Gilles; Mounier, Roman; Le Borgne, Pierrick; Couraud, Sophie; Herbrecht, Jean-Etienne; 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G.; Herbland, Alexandre; Richard, Marie; Girard, Nicolas; Lambron, Lucile; Lesieur, Olivier; Wainschtein, Sarah; Hubert, Sidonie; Hugues, Albane; Tran, Marc; Bouillard, Philippe; Loteanu, Vlad; Leloup, Maxime; Laurent, Alexandra; Lheureux, Florent; Prestifilippo, Alessia; Cruz, Martin Delgado Maria; Romain, Rigal; Antonelli, Massimo; Blanch, Torra Lluis; Bonnetain, Franck; Grazzia-Bocci, Maria; Mancebo, Jordi; Samain, Emmanuel; Paul, Hebert; Capellier, Gilles; Zavgorodniaia, Taissa; Soichot, Marion; Malissin, Isabelle; Voicu, Sebastian; Garçon, Pierre; Goury, Antoine; Kerdjana, Lamia; Deye, Nicolas; Bourgogne, Emmanuel; Megarbane, Bruno; Mejri, Olfa; Hmida, Marwa Ben; Tannous, Salma; Chevillard, Lucie; Labat, Laurence; Risede, Patricia; Fredj, Hana; Léger, Maxime; Brunet, Marion; Le Roux, Gaël; Boels, David; Lerolle, Nicolas; Farah, Souaad; Amiel-Niemann, Hélène; Kubis, Nathalie; Declèves, Xavier; Peyraux, Nicoals; Baud, Frederic; Serafini, Micaela; Alvarez, Jean-Claude; Heinzelman, Annette; 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Lacherade, Jean-Claude; Lebert, Christine; Vinatier, Isabelle; Yehia, Aihem; Joret, Aurélie; Menunier-Beillard, Nicolas; Benzekri-Lefevre, Dalila; Desachy, Arnaud; Bellec, Fréderic; Plantefève, Gaëtan; Quenot, Jean-Pierre; Meziani, Ferhat; Tavernier, Elsa; Ehrmann, Stephan; Chudeau, Nicolas; Raveau, Tommy; Moal, Valérie; Houillier, Pascal; Rouve, Emmanuelle; Lakhal, Karim; Gandonnière, Charlotte Salmon; Jouan, Youenn; Bodet-Contentin, Laetitia; Balmier, Adrien; Messika, Jonathan; De Montmollin, Etienne; Pouyet, Victorine; Sztrymf, Benjamin; Thiagarajah, Abirami; Roux, Damien; De Chambrun, Marc Pineton; Luyt, Charles-Edouard; Beloncle, François; Zapella, Nathalie; Ledochowsky, Stanislas; Terzi, Nicolas; Mazou, Jean-Marc; Sonneville, Romain; Paulus, Sylvie; Fedun, Yannick; Landais, Mickael; Raphalen, Jean-Herlé; Combes, Alain; Amoura, Zahir; Jacquemin, Aemilia; Guerrero, Felipe; Marcheix, Bertrand; Hernandez, Nicolas; Fourcade, Olivier; Georges, Bernard; Delmas, Clément; Makoudi, Sarah; Genton, Audrey; Bernard, Rémy; Lebreton, Guillaume; Amour, Julien; Mazet, Charlotte; Bounes, Fanny; Murat, Gurbuz; Cronier, Laure; Robin, Guillaume; Biendel, Caroline; Silva, Stein; Boubeche, Samia; Abriou, Caroline; Wurtz, Véronique; Scherrer, Vincent; Rey, Nathalie; Gastaldi, Gioia; Veber, Benoit; Doguet, Fabien; Gay, Arnaud; Dureuil, Bertrand; Besnier, Emmanuel; Rouget, Antoine; Gantois, Guillaume; Magalhaes, Eric; Wanono, Ruben; Smonig, Roland; Lermuzeaux, Mathilde; Lebut, Jordane; Olivier, Andremont; Dupuis, Claire; Radjou, Aguila; Mourvillier, Bruno; Neuville, Mathilde; D’ortho, Marie Pia; Bouadma, Lila; Rouvel-Tallec, Anny; Rudler, Marika; Weiss, Nicolas; Perlbarg, Vincent; Galanaud, Damien; Thabut, Dominique; Rachdi, Emna; Mhamdi, Ghada; Trifi, Ahlem; Abdelmalek, Rim; Abdellatif, Sami; Daly, Foued; Nasri, Rochdi; Tiouiri, Hanene; Lakhal, Salah Ben; Rousseau, Geoffroy; Asmolov, Romain; Grammatico-Guillon, Leslie; Auvet, Adrien; Laribi, Said; Garot, Denis; Dequin, Pierre François; Guillon, Antoine; Fergé, Jean-Louis; Abgrall, Gwénolé; Hinault, Ronan; Vally, Shazima; Roze, Benoit; Chaplain, Agathe; Chabartier, Cyrille; Savidan, Anne-Charlotte; Marie, Sabia; Cabie, Andre; Resiere, Dabor; Valentino, Ruddy; Mehdaoui, Hossein; Benarous, Lucas; Soda-Diop, Marième; Bouzana, Fouad; Perrin, Gilles; Bourenne, Jeremy; Eon, Béatrice; Lambert, Dominique; Trebuchon, Agnes; Poncelet, Géraldine; Le Bourgeois, Fleur; Michael, Levy; Camille, Guillot; Naudin, Jérôme; Deho, Anna; Dauger, Stéphane; Sauthier, Michaël; Bergeron-Gallant, Krystale; Emeriaud, Guillaume; Jouvet, Philippe; Tiebergien, Nicolas; Jacquet-Lagrèze, Matthias; Fellahi, Jean-Luc; Baudin, Florent; Essouri, Sandrine; Javouhey, Etienne; Guérin, Claude; Lampin, Marie; Mamouri, Ouardia; Devos, Patrick; Karaca-Altintas, Yasemin; Vinchon, Matthieu; Brossier, David; Eltaani, Redha; Teyssedre, Sonia; Sabine, Meyet; Bouchut, Jean-Christophe; Peguet, Olivier; Petitdemange, Lucie; Guilbert, Anne Sophie; Aoul, Nabil Tabet; Addou, Zakaria; Aouffen, Nabil; Anas, Benqqa; Kalouch, Samira; Yaqini, Khalid; Chlilek, Aziz; Abdou, Rchi; Gravellier, Perrine; Chantreuil, Julie; Travers, Nadine; Listrat, Antoine; Le Reun, Claire; Favrais, Geraldine; Coppere, Zoe; Blanot, Stéphane; Montmayeur, Juliette; Bronchard, Régis; Rolando, Stephane; Orliaguet, Gilles; Leger, Pierre-Louis; Rambaud, Jérôme; Thueux, Emilie; De Larrard, Alexandra; Berthelot, Véronique; Denot, Julien; Reymond, Marie; Amblard, Alain; Morin-Zorman, Sarah; Lengliné, Etienne; Pichereau, Claire; Mariotte, Eric; Emmanuel, Canet; Poujade, Julien; Trumpff, Guillaume; Janssen-Langenstein, Ralf; Harlay, Marie-Line; Zaid, Noorah; Ait-Ammar, Nawel; Bonnal, Christine; Merle, Jean-Claude; Botterel, Francoise; Levesque, Eric; Riad, Zakaria; Mezidi, Mehdi; Yonis, Hodane; Aublanc, Mylène; Perinel-Ragey, Sophie; Lissonde, Floriane; Louf-Durier, Aurore; Tapponnier, Romain; Louis, Bruno; Forel, Jean-Marie; Bisbal, Magali; Lehingue, Samuel; Rambaud, Romain; Adda, Mélanie; Hraiech, Sami; Marchi, Elisa; Roch, Antoine; Guerin, Vincent; Rozencwajg, Sacha; Schmidt, Matthieu; Hekimian, Guillaume; Bréchot, Nicolas; Trouillet, Jean Louis; Besset, Sébastien; Franchineau, Guillaume; Nieszkowska, Ania; Pascal, Leprince; Loiselle, Maud; Sarah, Chemam; Laurence, Dangers; Guillemette, Thomas; Jacquens, Alice; Kerever, Sebastien; Guidet, Bertrand; Aegerter, Philippe; Das, Vincent; Fartoukh, Muriel; Hayon, Jan; Desmard, Mathieu; Fulgencio, Jean-Pierre; Zuber, Benjamin; Soufi, A.; Khaleq, K.; Hamoudi, D.; Garret, Charlotte; Peron, Matthieu; Coron, Emmanuel; Bretonnière, Cédric; Audureau, Etienne; Audrey, Winters; Christophe, Duvoux; Christian, Jacquelinet; Daniel, Azoulay; Cyrille, Feray; Aissaoui, Wissal; Rghioui, Kawtar; Haddad, Wafae; Barrou, Houcine; Carteaux-Taeib, Anna; Lupinacci, Renato; Manceau, Gilles; Jeune, Florence; Tresallet, Christophe; Habacha, Sahar; Fathallah, Ines; Zoubli, Aymen; Aloui, Rafaa; Kouraichi, Nadia; Jouet, Emilie; Badin, Julie; Fermier, Brice; Feller, Marc; Serie, Mathieu; Pillot, Jérôme; Marie, William; Gisbert-Mora, Chloé; Vinclair, Camille; Lesbordes, Pierre; Mathieu, Pascal; De Brabant, Fabienne; Muller, Emmanuel; Robaux, Marie-Aline; Giabicani, Mikhael; Marchalot, Antoine; Gelinotte, Stéphanie; Declercq, Pierre Louis; Eraldi, Jean-Pierre; Bougerol, François; Meunier-Beillard, Nicolas; Devilliers, Hervé; Rigaud, Jean-Philippe; Verrière, Camille; Ardisson, Fanny; Kentish-Barnes, Nancy; Jacq, Gwenaëlle; Chermak, Akli; Lautrette, Alexandre; Legrand, Matthieu; Soummer, Alexis; Thiery, Guillaume; Cottereau, Alice; Canet, Emmanuel; Caujolle, Marie; Allyn, Jérôme; Valance, Dorothée; Brulliard, Caroline; Martinet, Olivier; Jabot, Julien; Gallas, Thomas; Vandroux, David; Allou, Nicolas; Durand, Arthur; Nevière, Rémi; Delguste, Florian; Boulanger, Eric; Preau, Sebastien; Martin, Ruste; Cochet, Hélène; Ponthus, Jean Pierre; Amilien, Virginie; Tchir, Martial; Barsam, Elise; Ayoub, Mohsen; Georger, Jean Francois; Guillame, Izaute; Assaraf, Julie; Tripon, Simona; Mallet, Maxime; Barbara, Guilaume; Louis, Guillaume; Gaudry, Stéphane; Barbarot, Nicolas; Jamet, Angéline; Outin, Hervé; Gibot, Sébastien; Bollaert, Pierre-Edouard; Holleville, Mathilde; Legriel, Stéphane; Chateauneuf, Anne Laure; Cavelot, Sébastien; Moyer, Jean-Denis; Bedos, Jean Pierre; Merle, Philippe; Laine, Aurelie; Natalie, De Sa; Cornuault, Mathieu; Libot, Jérome; Asehnoune, Karim; Rozec, Bertrand; Dantal, Jacques; Videcoq, Michel; Degroote, Thècle; Jaillette, Emmanuelle; Zerimech, Farid; Malika, Balduyck; Llitjos, Jean-François; Amara, Marlène; Lacave, Guillaume; Pangon, Béatrice; Mavinga, José; Makunza, Joseph Nsiala; Mafuta, M. E.; Yanga, Yves; Eric, Amisi; Ilunga, Jp; Kilembe, Ma; Alby-Laurent, Fanny; Toubiana, Julie; Mokline, Amel; Laajili, Achraf; Amri, Helmi; Rahmani, Imene; Mensi, Nidhal; Gharsallah, Lazheri; Tlaili, Sofiene; Gasri, Bahija; Hammouda, Rym; Messadi, Amen Allah; Allain, Pierre-Antoine; Gault, Nathallie; Paugam-Burtz, Catherine; Foucrier, Arnaud; Chatbri, Bassem; Bourbiaa, Yousra; Thabet, Lamia; Neuschwander, Arthur; Vincent, Looten; Beck, Jennifer; Vibol, Chhor; Amelie, Yavchitz; Resche-Rigon, Matthieu; Pirracchio, Jean MantzRomain; Bureau, Côme; Decavèle, Maxens; Campion, Sébastien; Ainsouya, Roukia; Niérat, Marie-Cécile; Prodanovic, Hélène; Raux, Mathieu; Similowski, Thomas; Dubé, Bruno-Pierre; Demiri, Suela; Dres, Martin; May, Faten; Quintard, Hervé; Kounis, Ilias; Saliba, Faouzi; André, Stephane; Boudon, Marc; Ichai, Philippe; Younes, Aline; Nakad, Lionel; Coilly, Audrey; Antonini, Teresa; Sobesky, Rodolphe; De Martin, Eleonora; Samuel, Didier; Hubert, Noemie; Nay, Mai-Anh; Auchabie, Johann; Giraudeau, Bruno; Jean, Reignier; Darmon, Michaël; Ruckly, Stephane; Garrouste-Orgeas, Maïté; Gratia, Elisabeth; Goldgran-Toledano, Dany; Jamali, Samir; Dumenil, Anne Sylvie; Schwebel, Carole; Brisard, Laurent; Bizouarn, Philippe; Lepoivre, Thierry; Nicolet, Johanna; Rigal, Jean Christophe; Roussel, Jean Christian; Cheurfa, Cherifa; Abily, Julien; Lescot, Thomas; Page, Isaline; Warnier, Stéphanie; Nys, Monique; Rousseau, Anne-Françoise; Damas, Pierre; Uhel, Fabrice; Lesouhaitier, Mathieu; Grégoire, Murielle; Gaudriot, Baptiste; Gacouin, Arnaud; Le Tulzo, Yves; Flecher, Erwan; Tarte, Karin; Tadié, Jean-Marc; Georges, Quentin; Soares, M.; Jeon, Kyeongman; Oeyen, Sandra; Rhee, Chin Kook; Gruber, Pascale; Ostermann, Marlies; Hill, Quentin; Depuydt, Peter; Ferra, Christelle; Muller, Alice; Aurelie, Bourmaud; Niles, Christopher; Herbert, Fabien; Pied, Sylviane; Loridant, Séverine; François, Nadine; Bignon, Anne; Sendid, Boualem; Lemaitre, Caroline; Dupre, Celine; Zayene, Aymen; Portier, Lucie; De Freitas Caires, Nathalie; Lassalle, Philippe; Le Neindre, Aymeric; Selot, Pascal; Ferreiro, Daniel; Bonarek, Maria; Henriot, Stépahen; Rodriguez, Julie; Taddei, Mara; Di Bari, Mauro; Hickmann, Cheryl; Castanares-Zapatero, Diego; Deldicque, Louise; Van Den Bergh, Peter; Caty, Gilles; Roeseler, Jean; Francaux, Marc; Laterre, Pierre-François; Dupuis, Bastien; Machayeckhi, Sharam; Sarfati, Celine; Moore, Alex; Mendialdua, Paula; Rodet, Emilie; Pilorge, Catherine; Stephan, Francois; Rezaiguia-Delclaux, Saida; Dugernier, Jonathan; Hesse, Michel; Jumetz, Thibaud; Bialais, Emilie; Depoortere, Virginie; Michotte, Jean Bernard; Wittebole, Xavier; Jamar, François title: Proceedings of Réanimation 2017, the French Intensive Care Society International Congress date: 2017-01-10 journal: Ann Intensive Care DOI: 10.1186/s13613-016-0224-7 sha: doc_id: 14538 cord_uid: 6a2pviol file: cache/cord-282660-9x937eus.json key: cord-282660-9x937eus authors: Muñoz Vives, Josep Maria; Jornet-Gibert, Montsant; Cámara-Cabrera, J.; Esteban, Pedro L.; Brunet, Laia; Delgado-Flores, Luis; Camacho-Carrasco, P.; Torner, P.; Marcano-Fernández, Francesc title: Mortality Rates of Patients with Proximal Femoral Fracture in a Worldwide Pandemic: Preliminary Results of the Spanish HIP-COVID Observational Study date: 2020-05-06 journal: J Bone Joint Surg Am DOI: 10.2106/jbjs.20.00686 sha: doc_id: 282660 cord_uid: 9x937eus file: cache/cord-355892-9kkqmm6h.json key: cord-355892-9kkqmm6h authors: Miller, Larry E.; Bhattacharyya, Ruemon; Miller, Anna L. title: Diabetes mellitus increases the risk of hospital mortality in patients with Covid-19: Systematic review with meta-analysis date: 2020-10-02 journal: Medicine (Baltimore) DOI: 10.1097/md.0000000000022439 sha: doc_id: 355892 cord_uid: 9kkqmm6h file: cache/cord-284786-pua14ogz.json key: cord-284786-pua14ogz authors: Coker, Eric S.; Cavalli, Laura; Fabrizi, Enrico; Guastella, Gianni; Lippo, Enrico; Parisi, Maria Laura; Pontarollo, Nicola; Rizzati, Massimiliano; Varacca, Alessandro; Vergalli, Sergio title: The Effects of Air Pollution on COVID-19 Related Mortality in Northern Italy date: 2020-08-04 journal: Environ Resour Econ (Dordr) DOI: 10.1007/s10640-020-00486-1 sha: doc_id: 284786 cord_uid: pua14ogz file: cache/cord-005777-6rvfsx4p.json key: cord-005777-6rvfsx4p authors: nan title: PS 0420-0716 date: 2007-08-25 journal: Intensive Care Med DOI: 10.1007/s00134-007-0823-8 sha: doc_id: 5777 cord_uid: 6rvfsx4p file: cache/cord-305936-tdswzj7r.json key: cord-305936-tdswzj7r authors: Freitas, André Ricardo Ribas; Donalisio, Maria Rita title: Excess of Mortality in Adults and Elderly and Circulation of Subtypes of Influenza Virus in Southern Brazil date: 2018-01-08 journal: Front Immunol DOI: 10.3389/fimmu.2017.01903 sha: doc_id: 305936 cord_uid: tdswzj7r file: cache/cord-314152-wd153s1g.json key: cord-314152-wd153s1g authors: Noor, Farha Musharrat; Islam, Md. Momin title: Prevalence and Associated Risk Factors of Mortality Among COVID-19 Patients: A Meta-Analysis date: 2020-09-12 journal: J Community Health DOI: 10.1007/s10900-020-00920-x sha: doc_id: 314152 cord_uid: wd153s1g file: cache/cord-005816-i54q5gsu.json key: cord-005816-i54q5gsu authors: nan title: 10(th) European Congress of Trauma and Emergency Surgery: May 13–17, 2009 Antalya, Turkey date: 2009-08-06 journal: Eur J Trauma Emerg Surg DOI: 10.1007/s00068-009-8001-z sha: doc_id: 5816 cord_uid: i54q5gsu file: cache/cord-299613-5ju5fcf4.json key: cord-299613-5ju5fcf4 authors: Arthi, Vellore; Parman, John title: Disease, downturns, and wellbeing: Economic history and the long-run impacts of COVID-19 date: 2020-11-03 journal: Explor Econ Hist DOI: 10.1016/j.eeh.2020.101381 sha: doc_id: 299613 cord_uid: 5ju5fcf4 file: cache/cord-351163-lyj94xn8.json key: cord-351163-lyj94xn8 authors: Rocha-Singh, Krishna J. title: Retrospective Real-World Studies of Paclitaxel and Mortality: Defining the Many Faces of Bias date: 2020-05-14 journal: JACC Cardiovasc Interv DOI: 10.1016/j.jcin.2020.05.006 sha: doc_id: 351163 cord_uid: lyj94xn8 file: cache/cord-294350-6veeygzp.json key: cord-294350-6veeygzp authors: Yu, Caizheng; Lei, Qing; Li, Wenkai; Wang, Xiong; Liu, Wei; Fan, Xionglin; Li, Wengang title: Clinical Characteristics, Associated Factors, and Predicting COVID-19 Mortality Risk: A Retrospective Study in Wuhan, China date: 2020-05-27 journal: Am J Prev Med DOI: 10.1016/j.amepre.2020.05.002 sha: doc_id: 294350 cord_uid: 6veeygzp file: cache/cord-013338-0jlxuksk.json key: cord-013338-0jlxuksk authors: Duong, William; Grigorian, Areg; Nahmias, Jeffry; Farzaneh, Cyrus; Christian, Ashton; Dolich, Matthew; Lekawa, Michael; Schubl, Sebastian title: An increasing trend in geriatric trauma patients undergoing surgical stabilization of rib fractures date: 2020-10-23 journal: Eur J Trauma Emerg Surg DOI: 10.1007/s00068-020-01526-7 sha: doc_id: 13338 cord_uid: 0jlxuksk file: cache/cord-335975-m6lkrehi.json key: cord-335975-m6lkrehi authors: nan title: Proceedings of Réanimation 2018, the French Intensive Care Society International Congress date: 2018-02-05 journal: Ann Intensive Care DOI: 10.1186/s13613-017-0345-7 sha: doc_id: 335975 cord_uid: m6lkrehi file: cache/cord-352685-0ie6tkgm.json key: cord-352685-0ie6tkgm authors: Coleman, T. S. title: Estimating Lower Bounds for COVID-19 Mortality from Northern Italian Towns date: 2020-06-12 journal: nan DOI: 10.1101/2020.06.10.20125005 sha: doc_id: 352685 cord_uid: 0ie6tkgm file: cache/cord-003532-lcgeingz.json key: cord-003532-lcgeingz authors: nan title: 39th International Symposium on Intensive Care and Emergency Medicine: Brussels, Belgium, 19-22 March 2019 date: 2019-03-19 journal: Crit Care DOI: 10.1186/s13054-019-2358-0 sha: doc_id: 3532 cord_uid: lcgeingz file: cache/cord-005497-w81ysjf9.json key: cord-005497-w81ysjf9 authors: nan title: 40th International Symposium on Intensive Care & Emergency Medicine: Brussels, Belgium. 24-27 March 2020 date: 2020-03-24 journal: Crit Care DOI: 10.1186/s13054-020-2772-3 sha: doc_id: 5497 cord_uid: w81ysjf9 file: cache/cord-014996-p6q0f37c.json key: cord-014996-p6q0f37c authors: nan title: Posters_Monday_12 October 2009 date: 2009-08-06 journal: Intensive Care Med DOI: 10.1007/s00134-009-1593-2 sha: doc_id: 14996 cord_uid: p6q0f37c file: cache/cord-014464-m5n250r2.json key: cord-014464-m5n250r2 authors: Sole-Violan, J; Sologuren, I; Betancor, E; Zhang, S; Pérez, C; Herrera-Ramos, E; Martínez-Saavedra, M; López-Rodríguez, M; Pestano, J; Ruiz-Hernández, J; Ferrer, J; Rodríguez de Castro, F; Casanova, J; Rodríguez-Gallego, C title: Lethal influenza virus A H1N1 infection in two relatives with autosomal dominant GATA-2 deficiency date: 2013-03-19 journal: Crit Care DOI: 10.1186/cc11953 sha: doc_id: 14464 cord_uid: m5n250r2 file: cache/cord-355038-o2hr5mox.json key: cord-355038-o2hr5mox authors: nan title: Proceedings of Réanimation 2020, the French Intensive Care Society International Congress date: 2020-02-11 journal: Ann Intensive Care DOI: 10.1186/s13613-020-0623-7 sha: doc_id: 355038 cord_uid: o2hr5mox file: cache/cord-010980-sizuef1v.json key: cord-010980-sizuef1v authors: nan title: ECTES Abstracts 2020 date: 2020-05-11 journal: Eur J Trauma Emerg Surg DOI: 10.1007/s00068-020-01343-y sha: doc_id: 10980 cord_uid: sizuef1v file: cache/cord-341063-3rqnu5bu.json key: cord-341063-3rqnu5bu authors: nan title: 38th International Symposium on Intensive Care and Emergency Medicine: Brussels, Belgium. 20-23 March 2018 date: 2018-03-29 journal: Crit Care DOI: 10.1186/s13054-018-1973-5 sha: doc_id: 341063 cord_uid: 3rqnu5bu file: cache/cord-005814-ak5pq312.json key: cord-005814-ak5pq312 authors: nan title: 8th European Congress of Intensive Care Medicine Athens - Greece, October 18–22, 1995 Abstracts date: 1995 journal: Intensive Care Med DOI: 10.1007/bf02426401 sha: doc_id: 5814 cord_uid: ak5pq312 Reading metadata file and updating bibliogrpahics === updating bibliographic database Building study carrel named keyword-mortality-cord === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 48166 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 48246 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 48402 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 47093 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 48710 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 49787 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 50539 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 50013 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 50164 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 48917 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 49412 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === id: cord-261377-m5djp8mh author: Grech, Victor title: COVID-19 and potential global mortality - Revisited date: 2020-04-30 pages: extension: .txt txt: ./txt/cord-261377-m5djp8mh.txt cache: ./cache/cord-261377-m5djp8mh.txt Content-Encoding ISO-8859-1 Content-Type text/plain; charset=ISO-8859-1 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 2 resourceName b'cord-261377-m5djp8mh.txt' === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 48171 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === id: cord-306205-l42w2jyk author: Ransome, Yusuf title: Is investing in religious institutions a viable pathway to reduce mortality in the population? date: 2020-06-08 pages: extension: .txt txt: ./txt/cord-306205-l42w2jyk.txt cache: ./cache/cord-306205-l42w2jyk.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 3 resourceName b'cord-306205-l42w2jyk.txt' === file2bib.sh === id: cord-353895-tgn1kk07 author: Kavanagh, Matthew M title: Reckoning with mortality: global health, HIV, and the politics of data date: 2020-07-03 pages: extension: .txt txt: ./txt/cord-353895-tgn1kk07.txt cache: ./cache/cord-353895-tgn1kk07.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 2 resourceName b'cord-353895-tgn1kk07.txt' === file2bib.sh === id: cord-003011-vclnb0eh author: de Almeida, Carlos Podalirio Borges title: Predictors of In-Hospital Mortality among Patients with Pulmonary Tuberculosis: A Systematic Review and Meta-analysis date: 2018-05-08 pages: extension: .txt txt: ./txt/cord-003011-vclnb0eh.txt cache: ./cache/cord-003011-vclnb0eh.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 3 resourceName b'cord-003011-vclnb0eh.txt' === file2bib.sh === id: cord-337692-b89ow1mf author: Petti, S. title: Ecologic association between influenza and COVID-19 mortality rates in European countries date: 2020-09-11 pages: extension: .txt txt: ./txt/cord-337692-b89ow1mf.txt cache: ./cache/cord-337692-b89ow1mf.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 4 resourceName b'cord-337692-b89ow1mf.txt' === file2bib.sh === id: cord-003340-nqc1pduk author: Dahal, Sushma title: Natality Decline and Spatial Variation in Excess Death Rates During the 1918–1920 Influenza Pandemic in Arizona, United States date: 2018-07-26 pages: extension: .txt txt: ./txt/cord-003340-nqc1pduk.txt cache: ./cache/cord-003340-nqc1pduk.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 2 resourceName b'cord-003340-nqc1pduk.txt' === file2bib.sh === id: cord-294645-yzh8h7zo author: Freeman, David W. title: Association between GDF15, poverty and mortality in urban middle-aged African American and white adults date: 2020-08-07 pages: extension: .txt txt: ./txt/cord-294645-yzh8h7zo.txt cache: ./cache/cord-294645-yzh8h7zo.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 3 resourceName b'cord-294645-yzh8h7zo.txt' === file2bib.sh === id: cord-305936-tdswzj7r author: Freitas, André Ricardo Ribas title: Excess of Mortality in Adults and Elderly and Circulation of Subtypes of Influenza Virus in Southern Brazil date: 2018-01-08 pages: extension: .txt txt: ./txt/cord-305936-tdswzj7r.txt cache: ./cache/cord-305936-tdswzj7r.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 4 resourceName b'cord-305936-tdswzj7r.txt' === file2bib.sh === id: cord-337098-33yj5g5v author: Agarwal, Shivani title: Preadmission Diabetes-Specific Risk Factors for Mortality in Hospitalized Patients With Diabetes and Coronavirus Disease 2019 date: 2020-08-07 pages: extension: .txt txt: ./txt/cord-337098-33yj5g5v.txt cache: ./cache/cord-337098-33yj5g5v.txt Content-Encoding ISO-8859-1 Content-Type text/plain; charset=ISO-8859-1 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 3 resourceName b'cord-337098-33yj5g5v.txt' === file2bib.sh === id: cord-003571-upogtny6 author: Viboud, Cécile title: The 1918 Influenza Pandemic: Looking Back, Looking Forward date: 2018-10-20 pages: extension: .txt txt: ./txt/cord-003571-upogtny6.txt cache: ./cache/cord-003571-upogtny6.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 2 resourceName b'cord-003571-upogtny6.txt' === file2bib.sh === id: cord-280348-vrnxucye author: Argano, Christiano title: Pattern of comorbidities and 1-year mortality in elderly patients with COPD hospitalized in internal medicine wards: data from the RePoSI Registry date: 2020-07-27 pages: extension: .txt txt: ./txt/cord-280348-vrnxucye.txt cache: ./cache/cord-280348-vrnxucye.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 3 resourceName b'cord-280348-vrnxucye.txt' === file2bib.sh === id: cord-027259-f4sgobcz author: Metsker, Oleg title: Stroke ICU Patient Mortality Day Prediction date: 2020-05-23 pages: extension: .txt txt: ./txt/cord-027259-f4sgobcz.txt cache: ./cache/cord-027259-f4sgobcz.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 4 resourceName b'cord-027259-f4sgobcz.txt' === file2bib.sh === id: cord-290295-gl144dh9 author: Martínez-López, Joaquín title: Multiple myeloma and SARS-CoV-2 infection: clinical characteristics and prognostic factors of inpatient mortality date: 2020-10-19 pages: extension: .txt txt: ./txt/cord-290295-gl144dh9.txt cache: ./cache/cord-290295-gl144dh9.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 3 resourceName b'cord-290295-gl144dh9.txt' === file2bib.sh === id: cord-298201-z68j0c63 author: Schlüter, Benjamin-Samuel title: Long-term trends in seasonality of mortality in urban Madagascar: the role of the epidemiological transition date: 2020-02-06 pages: extension: .txt txt: ./txt/cord-298201-z68j0c63.txt cache: ./cache/cord-298201-z68j0c63.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 3 resourceName b'cord-298201-z68j0c63.txt' === file2bib.sh === id: cord-293861-n6733nfd author: Juhász, Attila title: Antithrombotic Preventive Medication Prescription Redemption and Socioeconomic Status in Hungary in 2016: A Cross-Sectional Study date: 2020-09-19 pages: extension: .txt txt: ./txt/cord-293861-n6733nfd.txt cache: ./cache/cord-293861-n6733nfd.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 2 resourceName b'cord-293861-n6733nfd.txt' === file2bib.sh === id: cord-000522-d498qj2b author: Vincent, Jean-Louis title: Reducing mortality in sepsis: new directions date: 2002-12-05 pages: extension: .txt txt: ./txt/cord-000522-d498qj2b.txt cache: ./cache/cord-000522-d498qj2b.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 4 resourceName b'cord-000522-d498qj2b.txt' === file2bib.sh === id: cord-015651-yhi83hgq author: Kovács, Katalin title: Social Disparities in the Evolution of an Epidemiological Profile: Transition Processes in Mortality Between 1971 and 2008 in an Industrialized Middle Income Country: The Case of Hungary date: 2014-03-25 pages: extension: .txt txt: ./txt/cord-015651-yhi83hgq.txt cache: ./cache/cord-015651-yhi83hgq.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 3 resourceName b'cord-015651-yhi83hgq.txt' === file2bib.sh === id: cord-299613-5ju5fcf4 author: Arthi, Vellore title: Disease, downturns, and wellbeing: Economic history and the long-run impacts of COVID-19 date: 2020-11-03 pages: extension: .txt txt: ./txt/cord-299613-5ju5fcf4.txt cache: ./cache/cord-299613-5ju5fcf4.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 4 resourceName b'cord-299613-5ju5fcf4.txt' === file2bib.sh === id: cord-015082-l629n8is author: nan title: Poster Sessions 323-461 date: 2002-08-29 pages: extension: .txt txt: ./txt/cord-015082-l629n8is.txt cache: ./cache/cord-015082-l629n8is.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 3 resourceName b'cord-015082-l629n8is.txt' === file2bib.sh === id: cord-015126-cyhcbk1j author: nan title: PS 0036-0344 date: 2007-08-25 pages: extension: .txt txt: ./txt/cord-015126-cyhcbk1j.txt cache: ./cache/cord-015126-cyhcbk1j.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 5 resourceName b'cord-015126-cyhcbk1j.txt' === file2bib.sh === id: cord-014538-6a2pviol author: Kamilia, Chtara title: Proceedings of Réanimation 2017, the French Intensive Care Society International Congress date: 2017-01-10 pages: extension: .txt txt: ./txt/cord-014538-6a2pviol.txt cache: ./cache/cord-014538-6a2pviol.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 6 resourceName b'cord-014538-6a2pviol.txt' === file2bib.sh === id: cord-005777-6rvfsx4p author: nan title: PS 0420-0716 date: 2007-08-25 pages: extension: .txt txt: ./txt/cord-005777-6rvfsx4p.txt cache: ./cache/cord-005777-6rvfsx4p.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 7 resourceName b'cord-005777-6rvfsx4p.txt' === file2bib.sh === id: cord-003532-lcgeingz author: nan title: 39th International Symposium on Intensive Care and Emergency Medicine: Brussels, Belgium, 19-22 March 2019 date: 2019-03-19 pages: extension: .txt txt: ./txt/cord-003532-lcgeingz.txt cache: ./cache/cord-003532-lcgeingz.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 8 resourceName b'cord-003532-lcgeingz.txt' === file2bib.sh === id: cord-005816-i54q5gsu author: nan title: 10(th) European Congress of Trauma and Emergency Surgery: May 13–17, 2009 Antalya, Turkey date: 2009-08-06 pages: extension: .txt txt: ./txt/cord-005816-i54q5gsu.txt cache: ./cache/cord-005816-i54q5gsu.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 10 resourceName b'cord-005816-i54q5gsu.txt' === file2bib.sh === id: cord-014996-p6q0f37c author: nan title: Posters_Monday_12 October 2009 date: 2009-08-06 pages: extension: .txt txt: ./txt/cord-014996-p6q0f37c.txt cache: ./cache/cord-014996-p6q0f37c.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 8 resourceName b'cord-014996-p6q0f37c.txt' === file2bib.sh === id: cord-335975-m6lkrehi author: nan title: Proceedings of Réanimation 2018, the French Intensive Care Society International Congress date: 2018-02-05 pages: extension: .txt txt: ./txt/cord-335975-m6lkrehi.txt cache: ./cache/cord-335975-m6lkrehi.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 19 resourceName b'cord-335975-m6lkrehi.txt' === file2bib.sh === id: cord-341063-3rqnu5bu author: nan title: 38th International Symposium on Intensive Care and Emergency Medicine: Brussels, Belgium. 20-23 March 2018 date: 2018-03-29 pages: extension: .txt txt: ./txt/cord-341063-3rqnu5bu.txt cache: ./cache/cord-341063-3rqnu5bu.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 18 resourceName b'cord-341063-3rqnu5bu.txt' === file2bib.sh === id: cord-355038-o2hr5mox author: nan title: Proceedings of Réanimation 2020, the French Intensive Care Society International Congress date: 2020-02-11 pages: extension: .txt txt: ./txt/cord-355038-o2hr5mox.txt cache: ./cache/cord-355038-o2hr5mox.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 10 resourceName b'cord-355038-o2hr5mox.txt' === file2bib.sh === id: cord-005497-w81ysjf9 author: nan title: 40th International Symposium on Intensive Care & Emergency Medicine: Brussels, Belgium. 24-27 March 2020 date: 2020-03-24 pages: extension: .txt txt: ./txt/cord-005497-w81ysjf9.txt cache: ./cache/cord-005497-w81ysjf9.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 15 resourceName b'cord-005497-w81ysjf9.txt' === file2bib.sh === id: cord-014464-m5n250r2 author: Sole-Violan, J title: Lethal influenza virus A H1N1 infection in two relatives with autosomal dominant GATA-2 deficiency date: 2013-03-19 pages: extension: .txt txt: ./txt/cord-014464-m5n250r2.txt cache: ./cache/cord-014464-m5n250r2.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 10 resourceName b'cord-014464-m5n250r2.txt' === file2bib.sh === id: cord-010980-sizuef1v author: nan title: ECTES Abstracts 2020 date: 2020-05-11 pages: extension: .txt txt: ./txt/cord-010980-sizuef1v.txt cache: ./cache/cord-010980-sizuef1v.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 10 resourceName b'cord-010980-sizuef1v.txt' === file2bib.sh === id: cord-005814-ak5pq312 author: nan title: 8th European Congress of Intensive Care Medicine Athens - Greece, October 18–22, 1995 Abstracts date: 1995 pages: extension: .txt txt: ./txt/cord-005814-ak5pq312.txt cache: ./cache/cord-005814-ak5pq312.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 12 resourceName b'cord-005814-ak5pq312.txt' Que is empty; done keyword-mortality-cord === reduce.pl bib === id = cord-280348-vrnxucye author = Argano, Christiano title = Pattern of comorbidities and 1-year mortality in elderly patients with COPD hospitalized in internal medicine wards: data from the RePoSI Registry date = 2020-07-27 pages = extension = .txt mime = text/plain words = 4641 sentences = 257 flesch = 39 summary = Chronic obstructive pulmonary disease (COPD) represents an important leading cause of morbidity and mortality with high economic and social costs: according to the WHO, COPD is the fourth most common cause of death worldwide, and it is estimated to be the third by 2020; furthermore, the global burden of COPD is expected to increase in the coming years, due to the prevalence of smoking and aging of the world population [1] . The following clinical characteristics were evaluated: respiratory and non-respiratory disease distribution at hospital admission (according to International Classification of Diseases-Ninth Revision); cognitive status and mood disorders (by the Short-Blessed-Test [SBT] [9] and the Geriatric-Depression-Scale [GDS] [10] ,respectively; performance in activities of daily living at hospital admission (measured by means of the Barthel Index [BI] [11] ; severity and comorbidity index(assessed by the Cumulative-Illness-Rating-Scale CIRS-s and CIRS-c, respectively) [12] , glomerular filtration rate (using the Chronic Kidney Disease Epidemiology Collaboration-formula [13] ), length of hospital stay, drugs prescriptions (at admission, discharge, at 3 and 12 months follow-up), destination at discharge, in-hospital and 3-month and 1-year mortality rate. cache = ./cache/cord-280348-vrnxucye.txt txt = ./txt/cord-280348-vrnxucye.txt === reduce.pl bib === id = cord-003011-vclnb0eh author = de Almeida, Carlos Podalirio Borges title = Predictors of In-Hospital Mortality among Patients with Pulmonary Tuberculosis: A Systematic Review and Meta-analysis date = 2018-05-08 pages = extension = .txt mime = text/plain words = 2833 sentences = 173 flesch = 45 summary = title: Predictors of In-Hospital Mortality among Patients with Pulmonary Tuberculosis: A Systematic Review and Meta-analysis The aim of this systematic review and meta-analysis is to identify predictors of in-hospital mortality among patients with PTB. Methods: We searched MEDLINE, EMBASE, and Global Health, for cohort and case-control studies that reported risk factors for in-hospital mortality in PTB. We therefore conducted a systematic review and meta-analysis to establish predictors of in-hospital mortality among patients with pulmonary TB. Eligible trials met the following criteria 1 : cohort or case-control design 2 ; explored risk factors for in-hospital mortality among patients with pulmonary TB in an adjusted analysis. This systematic review and meta-analysis is expected to serve as a basis for evidence to reduce in-hospital mortality in TB patients, and as a guide for future research based on identified knowledge gaps. Predictors of in-hospital mortality among patients with pulmonary tuberculosis: a protocol of systematic review and meta-analysis of observational studies cache = ./cache/cord-003011-vclnb0eh.txt txt = ./txt/cord-003011-vclnb0eh.txt === reduce.pl bib === id = cord-003571-upogtny6 author = Viboud, Cécile title = The 1918 Influenza Pandemic: Looking Back, Looking Forward date = 2018-10-20 pages = extension = .txt mime = text/plain words = 3831 sentences = 155 flesch = 41 summary = In the present commentary, we place these 12 articles in the context of a growing body of work on the archeo-epidemiology of past pandemics, the socioeconomic and geographic drivers of influenza mortality and natality impact, and renewed interest in immune imprinting mechanisms and the development of novel influenza vaccines. In the present commentary, we place these 12 articles in the context of a growing body of work on the archeo-epidemiology of past pandemics, the socioeconomic and geographic drivers of influenza mortality and natality impact, and renewed interest in immune imprinting mechanisms and the development of novel influenza vaccines. age patterns; history of epidemiology; influenza; mortality; pandemic; prior immunity One hundred years after the fact, the 1918 influenza pandemic remains one of the most important epidemics of the modern medical era; it was significant for its impact on both human health and the development of epidemiology and other medical sciences. cache = ./cache/cord-003571-upogtny6.txt txt = ./txt/cord-003571-upogtny6.txt === reduce.pl bib === id = cord-261377-m5djp8mh author = Grech, Victor title = COVID-19 and potential global mortality - Revisited date = 2020-04-30 pages = extension = .txt mime = text/plain words = 389 sentences = 34 flesch = 63 summary = title: COVID-19 and potential global mortality Revisited (1) In a previous paper,(2) this author attempted to assess potential COVID-19 continent-based mortality based on initial WHO data from China which estimated that 14% of infected cases are severe and require hospitalisation, 5% of infected cases are very severe and require intensive care admission, mostly for ventilation, and 4% of infected die. For this reason, the table in the initial paper showing continent and global estimates (2) has been recalculated with a correction factor, an estimated 10% symptomatic proportion of infected individuals. Clearly, this pandemic has the potential to be as severe in terms of mortality as the influenza pandemic of 1918 which killed more than 50 million people and caused more than 500 million infections worldwide.(5) The conclusions of the previous paper stand. Unknown unknowns -COVID-19 and potential global mortality cache = ./cache/cord-261377-m5djp8mh.txt txt = ./txt/cord-261377-m5djp8mh.txt === reduce.pl bib === id = cord-298201-z68j0c63 author = Schlüter, Benjamin-Samuel title = Long-term trends in seasonality of mortality in urban Madagascar: the role of the epidemiological transition date = 2020-02-06 pages = extension = .txt mime = text/plain words = 6359 sentences = 307 flesch = 54 summary = Objective: Based on death notification data from Antananarivo, the capital city of Madagascar, this study assesses seasonal patterns of all-cause and cause-specific mortality by age groups and evaluates how these patterns changed over the period 1976–2015. In adults aged 60 and above, all-cause mortality rates are the highest in the dry and cold season, due to peaks in cardiovascular diseases, with little change over time. Considering children aged 1 to 5, seasonality of mortality associated with these two broad causes of death (the group of diarrhea, lower respiratory, and other common infectious diseases, and the group of nutritional deficiencies) also exhibit this pattern but with a larger amplitude. In infants, the seasonality of deaths is dominated by the association between hot temperatures and rainfall, and two groups of causes: (1) diarrhea, lower respiratory, and other common infectious diseases, and (2) nutritional deficiencies. cache = ./cache/cord-298201-z68j0c63.txt txt = ./txt/cord-298201-z68j0c63.txt === reduce.pl bib === id = cord-337098-33yj5g5v author = Agarwal, Shivani title = Preadmission Diabetes-Specific Risk Factors for Mortality in Hospitalized Patients With Diabetes and Coronavirus Disease 2019 date = 2020-08-07 pages = extension = .txt mime = text/plain words = 3625 sentences = 163 flesch = 40 summary = OBJECTIVE: To examine whether HbA(1c), outpatient diabetes treatment regimen, demographics, and clinical characteristics are associated with mortality in hospitalized patients with diabetes and coronavirus disease 2019 (COVID-19). CONCLUSIONS: In this large U.S. cohort of hospitalized patients with diabetes and COVID-19, insulin treatment, as a possible proxy for diabetes duration, and obesity rather than long-term glycemic control were predictive of mortality. Few studies have specifically examined the effect of preadmission glycemic control in patients with diabetes and risk of in-hospital mortality from COVID-19, despite having great implications for outpatient glycemic management during the pandemic. The goal of this study was to use a U.S. cohort to examine the association of outpatient glycemic control, diabetes treatment, and other characteristics with mortality among hospitalized patients with diabetes and COVID-19. We investigated whether HbA 1c levels, outpatient diabetes treatment, and other characteristics were associated with in-hospital mortality among patients with COVID-19 and preexisting diabetes. cache = ./cache/cord-337098-33yj5g5v.txt txt = ./txt/cord-337098-33yj5g5v.txt === reduce.pl bib === id = cord-015651-yhi83hgq author = Kovács, Katalin title = Social Disparities in the Evolution of an Epidemiological Profile: Transition Processes in Mortality Between 1971 and 2008 in an Industrialized Middle Income Country: The Case of Hungary date = 2014-03-25 pages = extension = .txt mime = text/plain words = 11309 sentences = 512 flesch = 48 summary = One of main conclusions has been that they have not so far undergone the healthier life style changes that have occurred in Western Europe, and this has resulted in a "reversed epidemiological transition", in which an elevated burden of cardiovascular diseases dominates the pattern of mortality (Vallin and Meslé 2004) . In this paper I shall review recent developments in epidemiological transition theory, and test the applicability of some of these theories to the evolution of cause-and education-specific mortality inequalities in Hungary between 1971 and 2008. Omran, starting from his very first publication, continuously mentioned social disparities in mortality as well as the driving forces listed above but he did not provide a theoretical framework for the application of these in connection with particular mortality or disease patterns specific for single countries or population sub-groups. cache = ./cache/cord-015651-yhi83hgq.txt txt = ./txt/cord-015651-yhi83hgq.txt === reduce.pl bib === id = cord-337692-b89ow1mf author = Petti, S. title = Ecologic association between influenza and COVID-19 mortality rates in European countries date = 2020-09-11 pages = extension = .txt mime = text/plain words = 5103 sentences = 251 flesch = 41 summary = Ecologic studies investigating COVID-19 mortality determinants, used to make predictions and design public health control measures, generally focused on population-based variable counterparts of individual-based risk factors. We considered the 3-year average influenza (2014–2016) and COVID-19 (31 May 2020) crude mortality rates in 34 countries using EUROSTAT and ECDC databases and performed correlation and regression analyses. An apparently perplexing characteristic of the reported association between the two mortality rates was that while influenza virus circulation during the seasons considered in the present analysis was uncontrolled, SARS-CoV-2 circulation was probably limited by the widespread exceptional public health measures implemented in Europe [32] . This study reported an inverse association between number of hospital beds and mortality rates (Table 2) , thus showing that high influenza and COVID-19 mortality was also due to inefficiencies of the healthcare systems, and corroborated by data from several European countries [45] . cache = ./cache/cord-337692-b89ow1mf.txt txt = ./txt/cord-337692-b89ow1mf.txt === reduce.pl bib === id = cord-353895-tgn1kk07 author = Kavanagh, Matthew M title = Reckoning with mortality: global health, HIV, and the politics of data date = 2020-07-03 pages = extension = .txt mime = text/plain words = 1848 sentences = 94 flesch = 46 summary = Studies in South Africa, Kenya, Zambia, and the Democratic Republic of the Congo have shown that most patients with HIV admitted to hospital have already been on antiretroviral therapy (often for years) but they either stop treatment or are on a treatment regimen that is not effectively suppressing the virus. In South Africa, in particular, tracking the mortality of young people using systems at the local level helped monitor the effectiveness of HIV programmes. 20 Hopefully, this step will improve patient outcomes by incentivising effective interventions for advanced HIV disease and support for people who have stopped treatment to re-enter care. 17 Third, we can move towards a variety of outcomeoriented global health programmes beyond HIV, for which measures of success move from the number of patients receiving services to explicit reductions in mortality rates. cache = ./cache/cord-353895-tgn1kk07.txt txt = ./txt/cord-353895-tgn1kk07.txt === reduce.pl bib === === reduce.pl bib === id = cord-294645-yzh8h7zo author = Freeman, David W. title = Association between GDF15, poverty and mortality in urban middle-aged African American and white adults date = 2020-08-07 pages = extension = .txt mime = text/plain words = 4977 sentences = 221 flesch = 43 summary = Multivariable adjusted Cox regression models were used to assess the association between log-transformed GDF15 (logGDF15) and 12-year mortality outcomes (all-cause, cardiovascularand cancer-specific outcomes) and interactions with sex, race and poverty status. The objectives of the present study were to assess the association between serum GDF15 and all-cause and cause-specific mortality, and to identify interactions between GDF15 and sex, race and poverty status in a large cohort of community-based middle-aged adults recruited from Baltimore, Maryland. In a community-dwelling cohort of younger urban adults (mean age 49.6) with diverse racial and socioeconomic status, we found that elevated serum GDF15 level was strongly associated with all-cause mortality, CVD-and cancer-specific mortality risk. Our findings of increased risk of mortality due to all-causes and CVD and elevated GDF15 levels in a diverse cohort are consistent with results of previous studies conducted in apparently healthy, community-dwelling adults [12-15, 17, 18] . cache = ./cache/cord-294645-yzh8h7zo.txt txt = ./txt/cord-294645-yzh8h7zo.txt === reduce.pl bib === id = cord-000522-d498qj2b author = Vincent, Jean-Louis title = Reducing mortality in sepsis: new directions date = 2002-12-05 pages = extension = .txt mime = text/plain words = 8709 sentences = 431 flesch = 48 summary = Five topics were selected that have been shown in randomized, controlled trials to reduce mortality: limiting the tidal volume in acute lung injury or acute respiratory distress syndrome, early goal-directed therapy, use of drotrecogin alfa (activated), use of moderate doses of steroids, and tight control of blood sugar. The present article provides guidelines from experts in the field on optimal patient selection and timing for each intervention, and provides advice on how to integrate new therapies into ICU practice, including protocol development, so that mortality rates from this disease process can be reduced. The interventions discussed encompassed low tidal volume in patients with acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) (Edward Abraham), early goal-directed therapy (EGDT) (Emanuel Rivers), drotrecogin alfa (activated) (Gordon Bernard), moderate-dose corticosteroids (Djillali Annane), and tight control of blood sugar (Greet Van den Berghe). cache = ./cache/cord-000522-d498qj2b.txt txt = ./txt/cord-000522-d498qj2b.txt === reduce.pl bib === id = cord-306205-l42w2jyk author = Ransome, Yusuf title = Is investing in religious institutions a viable pathway to reduce mortality in the population? date = 2020-06-08 pages = extension = .txt mime = text/plain words = 2980 sentences = 156 flesch = 35 summary = The religious ecology or characteristics of religion within an area or geographic level (e.g., county, ZIP-code, country), has been linked with overall and cause-specific mortality, but directions of findings are mixed. The study found some support of an indirect association from county-level religious denominational composition, through investments in health spending, on Black and White all-cause mortality rates. Ecological studies have showed that religious ecology or characteristics of religion in area or geographic level (e.g., county, ZIP-code, country), is associated with overall and cause-specific mortality such as suicide rates (Stack 1980 , Dwyer, Clarke et al. The study found some support for an indirect association from county-level religious denominational composition to Black and White all-cause mortality rates, through investments in total institutional spending. The study (SSM-D-19-03928R2) investigated the mediating role of investments/spending in local health shaping institutions as a link between the religious ecology and all-cause mortality. cache = ./cache/cord-306205-l42w2jyk.txt txt = ./txt/cord-306205-l42w2jyk.txt === reduce.pl bib === id = cord-015126-cyhcbk1j author = nan title = PS 0036-0344 date = 2007-08-25 pages = extension = .txt mime = text/plain words = 59175 sentences = 3672 flesch = 54 summary = We compared them with ≥70 years old and an ICU stay < 30 days patients, the differences in ICU mortality, Apache II, age, gender and the necessity for renal replacement therapy (RRT) were not significant (see table) . The patients with mild form of acute pancreatitis had low mortality rate (similar to general ward population) despite positive ICU admission criteria in our case series with fifty per cent development of severe form with organ dysfunction/failure later on. Collected data:Demographics,Management prior and during ICU hospitalization (sedation, catecolamin drug use, blood product transfusion, intra-cranial pressure monitoring, neurosurgical emergency surgery etc.),CT-Scan results, Daily worst Glasgow coma scale, admission Simplified Acute Physiology Score II. This prospective interventional study performed in a surgical Intensive Care Unit of a tertiary University Hospital included 35 (21 males) mechanically ventilated and sedated patients with acute cardiovascular failure requiring cardiac output measurement (transpulmonary thermodilution technique)and a fluid challenge. cache = ./cache/cord-015126-cyhcbk1j.txt txt = ./txt/cord-015126-cyhcbk1j.txt === reduce.pl bib === id = cord-015082-l629n8is author = nan title = Poster Sessions 323-461 date = 2002-08-29 pages = extension = .txt mime = text/plain words = 26569 sentences = 1648 flesch = 52 summary = 14 patients awaiting urgent cardiac surgical re-vascularisation were studied with measurement of: spirometry; percentage increase in transfer factor from sitting to lying position (TF) as an indicator of micro-vascular lung disease; overnight oximetry on air; and 24hour holter monitoring Patients, who were reintubated on decreased indices of arterial oxygenation under MOSF progressing died in 100% cases ( NIMV is effective method in complex therapy of ARF, developing in postoperative period after cardiac surgery, that leads to significant improvement of lungs biomechanics and gases change function. In a prospective observational study we performed bedside ptO2 measurements in 8 patients with sepsis/septic shock to gain insight in ptO2 values and their dynamic changes related to the course of the illness, as well as investigating the practical applicability of tissue oxygen measurement in the ICU setting. cache = ./cache/cord-015082-l629n8is.txt txt = ./txt/cord-015082-l629n8is.txt === reduce.pl bib === id = cord-027259-f4sgobcz author = Metsker, Oleg title = Stroke ICU Patient Mortality Day Prediction date = 2020-05-23 pages = extension = .txt mime = text/plain words = 5328 sentences = 204 flesch = 42 summary = On the basis of the analysis of 12 modern prognostic models from 10 countries we can identify some of the most stable (main) predictors for the causes of intra-hospital mortality: age [16, [20] [21] [22] [23] [24] ; type of stroke [25] ; lesion location [25] ; level of consciousness [11, 20, 23, 25, 26] upon admission; NIHSS stroke severity [10, 21, 22, 24] ; comorbidity [22, 27] , Charlson comorbidity index [23] , Atrial fibrillation [11, 22] , case history Transitor ischemic attack (TIA) [31]; hospital complications (high intracranial pressure) [16] , pneumonia, seizures, anxiety/depression, infections, limb pains and constipation [22, 27] . Early mortality in each subgroup was associated with a number of demographic, clinical, and instrumental-laboratory characteristics based on the interpretation of the results of calculating the significance of predictors of binary classification models by machine learning methods from the Scikit-Learn library 2 . cache = ./cache/cord-027259-f4sgobcz.txt txt = ./txt/cord-027259-f4sgobcz.txt === reduce.pl bib === id = cord-293861-n6733nfd author = Juhász, Attila title = Antithrombotic Preventive Medication Prescription Redemption and Socioeconomic Status in Hungary in 2016: A Cross-Sectional Study date = 2020-09-19 pages = extension = .txt mime = text/plain words = 6067 sentences = 245 flesch = 32 summary = Risk analysis capabilities were applied to estimate the relationships between socioeconomic status, which was characterized by quintiles of a multidimensional composite indicator (deprivation index), and mortality due to thromboembolic diseases as well as antithrombotic medications for the year 2016 at the district level in Hungary. Although data on the level and availability of secondary prevention at the country level would be essential for planning and targeting national health system policies that can decrease premature CVD mortality and morbidity, only a few studies have been published on the link between the utilization of antiplatelet drugs and anticoagulants (hereafter antithrombotic agents) for preventive purposes and socioeconomic status. Since physicians in general practice play a major role in initiating, coordinating, and providing long-term follow-up for the prevention of non-communicable diseases [23] , our study examined the prescription and redemption rates of the most common oral antiplatelet drugs and anticoagulants prescribed for thrombosis prevention from all general practices and defined their relationships with socioeconomic status in Hungary. cache = ./cache/cord-293861-n6733nfd.txt txt = ./txt/cord-293861-n6733nfd.txt === reduce.pl bib === id = cord-290295-gl144dh9 author = Martínez-López, Joaquín title = Multiple myeloma and SARS-CoV-2 infection: clinical characteristics and prognostic factors of inpatient mortality date = 2020-10-19 pages = extension = .txt mime = text/plain words = 4086 sentences = 186 flesch = 36 summary = Among MM patients, inpatient mortality was 41% in males, 42% in patients aged >65 years, 49% in patients with active/progressive MM at hospitalization, and 59% in patients with comorbid renal disease at hospitalization, which were independent prognostic factors on adjusted multivariate analysis. There are cumulative data indicating that patients with cancer may be at increased risk for more severe COVID-19 and associated complications, including those receiving or not receiving treatment within the month prior to infection 5, 6 , although other recent results suggest mortality may be primarily associated with age, male sex, and comorbidities 7 . To our knowledge, this is the first large case-series study to describe comprehensively the clinical characteristics of COVID-19 in hospitalized MM patients, compare outcomes with a noncancer cohort of COVID-19 patients, and identify preadmission prognostic factors of inpatient mortality. cache = ./cache/cord-290295-gl144dh9.txt txt = ./txt/cord-290295-gl144dh9.txt === reduce.pl bib === id = cord-003340-nqc1pduk author = Dahal, Sushma title = Natality Decline and Spatial Variation in Excess Death Rates During the 1918–1920 Influenza Pandemic in Arizona, United States date = 2018-07-26 pages = extension = .txt mime = text/plain words = 3326 sentences = 167 flesch = 49 summary = title: Natality Decline and Spatial Variation in Excess Death Rates During the 1918–1920 Influenza Pandemic in Arizona, United States Moreover, excess mortality rates were highest in northern Arizona counties, where Native Americans were historically concentrated, suggesting a link between ethnic and/or sociodemographic factors and risk of pandemic-related death. Moreover, excess mortality rates were highest in northern Arizona counties, where Native Americans were historically concentrated, suggesting a link between ethnic and/or sociodemographic factors and risk of pandemic-related death. We also analyzed 21,334 individual birth certificates to quantify the impact of the 1918-1920 influenza pandemic on natality fluctuations in Maricopa county, the most populous county in Arizona state. Likewise, our results suggest that northern counties in Arizona with high Native American population density (e.g., Apache, Coconino, and Navajo) experienced higher excess pandemic death rates compared with other counties in the state. cache = ./cache/cord-003340-nqc1pduk.txt txt = ./txt/cord-003340-nqc1pduk.txt === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === id = cord-014538-6a2pviol author = Kamilia, Chtara title = Proceedings of Réanimation 2017, the French Intensive Care Society International Congress date = 2017-01-10 pages = extension = .txt mime = text/plain words = 61068 sentences = 3463 flesch = 49 summary = Other parameters that were significantly different between the patients who died and those who survived were an advanced age, an elevated IGS II score at hospital admission, an elevated SOFA score at study entry, a late healthcare-associated infection and several biological variables: a high C reactive protein, low albumin and prealbumin and a poor percent of monocytes expressing HLA-DR, all measured at day 7. Parameters collected were demographic features, comorbidities, regular treatment, dyspnea assessed by the MRC scale, initial clinical severity reflected by SAPS II and APACHE II scores, modalities and ICU admission deadlines, initial arterial blood gas analysis, management of patients in the ICU (ventilation modalities, prescription of antibiotics, use of vasoactive drugs) and their outcomes (incidence of nosocomial infections and their sites, length of stay and ICU mortality). cache = ./cache/cord-014538-6a2pviol.txt txt = ./txt/cord-014538-6a2pviol.txt === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === id = cord-005777-6rvfsx4p author = nan title = PS 0420-0716 date = 2007-08-25 pages = extension = .txt mime = text/plain words = 59217 sentences = 3634 flesch = 53 summary = We prospectively recorded data of all patients who were newly diagnosed with AF and all those with a septic shock on a surgical ICU (no cardiac surgery) during a one year period according to the requirements of the local ethical committee. Our aim was to evaluate the predictive role of admission APACHE II, admission and total maximum SOFA score, hypoalbuminemia, increased serum creatinine, C-reactive protein, lactate, and serum blood glucose for the 30-day mortality of septic patients admitted to medical ICU. The aim of this study was to analyze the clinical presentation and to evaluate mortality associated factors (timing and accurancy of diagnosis, timing of surgery, severity score and organ failure, surgical and medical treatments). Data were extracted independently to assess intention to treat intensive care unit (ICU) and hospital mortality, days of mechanical ventilation, length of stay, incidence of ventilator-associated pneumonia and pneumothorax, and associated complications of the implemented intervention. cache = ./cache/cord-005777-6rvfsx4p.txt txt = ./txt/cord-005777-6rvfsx4p.txt === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === id = cord-305936-tdswzj7r author = Freitas, André Ricardo Ribas title = Excess of Mortality in Adults and Elderly and Circulation of Subtypes of Influenza Virus in Southern Brazil date = 2018-01-08 pages = extension = .txt mime = text/plain words = 4343 sentences = 193 flesch = 39 summary = Despite not controlling for comorbidities, climate, and vaccination, for the >70 years, ratio of respiratory diseases excess mortality rates between AH1N1 (2009) and severe year of H3N2 (2007) shows protection in the pandemic year and great vulnerability during AH3N2 virus predominance. We analyzed particularly the most predominant variants (AH1N1 and AH3N2) on excess of mortality in the adults and elderly of different age groups in a region with marked seasonality of respiratory diseases in Brazil. Among adults (24-59 years), we observe a large excess of deaths rates during the 2009 pandemic (953 obits), which correspond to 7.1 excess deaths from all causes, and 99 excess mortality from respiratory diseases associated with viral infection in every 100,000 individuals of the age group. Although the elderly are the most vulnerable group to viral respiratory infections, we found relative small excess of deaths in years of circulating AH1N1 pre pandemic (2002 and 2008) . cache = ./cache/cord-305936-tdswzj7r.txt txt = ./txt/cord-305936-tdswzj7r.txt === reduce.pl bib === === reduce.pl bib === id = cord-005816-i54q5gsu author = nan title = 10(th) European Congress of Trauma and Emergency Surgery: May 13–17, 2009 Antalya, Turkey date = 2009-08-06 pages = extension = .txt mime = text/plain words = 83124 sentences = 5617 flesch = 53 summary = Several factors such as the initial lack of symptoms, a low diagnostic sensitivity of the CT (34% false negatives), and the nonoperative management of solid organ injuries, have contributed to a delayed diagnosis in one of every five patients in our series, but this has not led to a significant increase in septic complications in this group. Method: The demographic features, the treatments, the intensity of the illness and mortality rate of the 155 patients in Afyon Kocatepe University General Surgery clinic between the years 2006 Background: Enterocutaneous fistula continues to be a serious surgical problem. Introduction: In our previous study, we examined the treatment results of burn patients older than 45 years, and found a significant increase in mortality with increasing age groups. Methods: Data on emergency surgical cases and admissions to the surgical service over a 3-month period were collected and analyzed; this included patient demographics, referral sources, diagnosis, operation, and length of stay (LOS Conclusion: Emergency workload represents a significant part of the work for the general surgeons. cache = ./cache/cord-005816-i54q5gsu.txt txt = ./txt/cord-005816-i54q5gsu.txt === reduce.pl bib === id = cord-299613-5ju5fcf4 author = Arthi, Vellore title = Disease, downturns, and wellbeing: Economic history and the long-run impacts of COVID-19 date = 2020-11-03 pages = extension = .txt mime = text/plain words = 17509 sentences = 810 flesch = 48 summary = In this paper, we review the evidence on the long-run effects on health, labor, and human capital of both historical pandemics (with a focus on the 1918 Influenza Pandemic) and historical recessions (with a focus on the Great Depression). Thus, a historical perspective allows us to use rich data to look at not only the short-term effects of crises like COVID-19 on health, labor, and human capital, but also the long-term and intergenerational impacts along these dimensions for both individuals and the wider economy. To examine how history can inform our view of the coronavirus pandemic and associated policy responses as they relate to long-run wellbeing, we begin in Section II by reviewing the features of COVID-19 that will determine its potential health and economic impacts, and placing these features in historical context. cache = ./cache/cord-299613-5ju5fcf4.txt txt = ./txt/cord-299613-5ju5fcf4.txt === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === id = cord-335975-m6lkrehi author = nan title = Proceedings of Réanimation 2018, the French Intensive Care Society International Congress date = 2018-02-05 pages = extension = .txt mime = text/plain words = 89374 sentences = 5327 flesch = 52 summary = A qSOFA score relying on 3 simple clinical criteria (respiratory rate, mental status and systolic blood pressure) has been proposed to better identify septic patients with associated higher mortality outside the intensive care unit (Seymour CW et al., JAMA 2016) . We propose to determine whether the arterial oxygen pressure (PaO2) at intensive care unit (ICU) admission affects mortality at day 28 (D28) in patients with septic shock subjected to mechanical out-of-hospital ventilation. Conclusion: In this study, we report a significant association between hyperoxemia at ICU admission and mortality at D28 in patients with septic shock subjected to pre-hospital invasive mechanical ventilation. The aim of this study was to describe outcome of pediatric patient with hematologic disease hospitalized in our intensive care unit for respiratory failure and to investigate the clinical variables associated with mortality. cache = ./cache/cord-335975-m6lkrehi.txt txt = ./txt/cord-335975-m6lkrehi.txt === reduce.pl bib === === reduce.pl bib === id = cord-003532-lcgeingz author = nan title = 39th International Symposium on Intensive Care and Emergency Medicine: Brussels, Belgium, 19-22 March 2019 date = 2019-03-19 pages = extension = .txt mime = text/plain words = 79997 sentences = 5146 flesch = 52 summary = It's proposed to evaluate the association between myocardial injury biomarkers, high-sensitive troponin T (hs-cTnT) and N-terminal pro-brain natriuretic peptide (NT-ProBNP), with inflammatory mediators (IL-6, IL-1Β , IL-8, IL-10, IL-12 / IL-23p40, IL17A, IL-21 and TNF-α ) and biomarkers, C protein reactive (CPR) and procalcitonin (PCT), in septic patients Methods: This was a prospective cohort study performed in three intensive care units, from September 2007 to September 2010 enrolling patients with sepsis (infection associated with organ dysfunction), and septic shock (hypotension refractory by fluids infusion requiring vasopressor). Blood samples were collected up to 48h after the development of first organ dysfunction (D0) and on the 7th day after inclusion in the study (D7) Results: Ninety-five patients were enrolled, with median age 64 years (interquatile?48-78), APACHE II: median 19 (14-22), SOFA: median 8 (5-10); 24.2% were admitted in ICU with sepsis and 75.8% with septic shock. cache = ./cache/cord-003532-lcgeingz.txt txt = ./txt/cord-003532-lcgeingz.txt === reduce.pl bib === id = cord-014996-p6q0f37c author = nan title = Posters_Monday_12 October 2009 date = 2009-08-06 pages = extension = .txt mime = text/plain words = 85190 sentences = 5288 flesch = 54 summary = Data recorded on admission were the patient demographics with, acute physiology and chronic health evaluation II score (APACHE II), and type of admission; during intensive care stay, sepsis-related organ failure assessment score (SOFA) and clinical concomitant factors and conditions. For each severe septic patient the following data was registered: time delay, APACHE II and SOFA scores at ICU admission, diagnosis, the rate of compliance with the resucitation and management bundles, microbiological data, evolution of levels of serum lactate, empiric antibiotic therapy, length of stay and mortality in ICU. Sepsis and septic shock remain the most important causes of acute kidney injury (AKI) in critically ill patients and account for more than 50% of cases of acute renal failure (ARF) in intensive care units (ICU). There were no significant differences between the demographic data (sex, age) or the data on admission to intensive care (APACHE II score, ratio of medical to surgical patients) and duration of mechanical ventilation between the two groups. cache = ./cache/cord-014996-p6q0f37c.txt txt = ./txt/cord-014996-p6q0f37c.txt === reduce.pl bib === id = cord-005497-w81ysjf9 author = nan title = 40th International Symposium on Intensive Care & Emergency Medicine: Brussels, Belgium. 24-27 March 2020 date = 2020-03-24 pages = extension = .txt mime = text/plain words = 103623 sentences = 6176 flesch = 53 summary = The positive NC group had more plasma transfusion (p-value 0.03) and a lower median hematocrit at 24 hrs (p-value 0.013), but similar hospital length of stay (p=0.17) and mortality rate (p=0.80) Conclusions: NC at ICU admission identifies subclinical AKI in TBI patients and it maight be used to predictclinical AKI. In patients with pneumonia requiring intensive care (ICU) admission, we hypothesise that abnormal right ventricular (RV) function is associated with an increased 90-day mortality. The objective of this study was to describe the incidence of each AKI stages as defined by KDIGO definition (with evaluation of urine output, serum creatinine and initiation of renal replacement therapy (RRT)), in a mixed medical and surgical population of patients hospitalized in ICU and PCU over a 10-year period (2008-2018). This study aimed at investigating the relationship of goal-directed energy and protein adequacy on clinical outcomes which includes mortality, intensive care unit(ICU) and hospital length of stay (LOS), and length of mechanical ventilation (LOMV). cache = ./cache/cord-005497-w81ysjf9.txt txt = ./txt/cord-005497-w81ysjf9.txt === reduce.pl bib === id = cord-014464-m5n250r2 author = Sole-Violan, J title = Lethal influenza virus A H1N1 infection in two relatives with autosomal dominant GATA-2 deficiency date = 2013-03-19 pages = extension = .txt mime = text/plain words = 98961 sentences = 5553 flesch = 54 summary = Results In preliminary analysis of categorical data, a signifi cantly (Fisher exact test) greater proportion of patients with compared with without the following fi ndings did not survive; history of alcohol use (P = 0.05); the presence of lethargy (P = 0.01), confusion (P = 0.03), nausea (P = 0.04), abdominal pain (P = 0.02), or the need for vasopressors (P = 0.002), oxygen, mechanical ventilation, or steroids (all P = 0.004) at presentation; and excessive bleeding at surgery (P = 0.01). Methods To prospectively re-evaluate the normal range and to analyze the potential impact of biometric data on ICG-PDR, we measured ICG-PDR (i.v. injection of 0.25 mg/kg ICG; LiMON, Pulsion, Munich, Introduction Mixed venous oxygen saturation (SVO 2 ) represents a well-recognized parameter of oxygen delivery (DO 2 )-consumption (VO 2 ) mismatch and its use has been advocated in critically ill patients in order to guide hemodynamic resuscitation [1] and oxygen delivery optimization. cache = ./cache/cord-014464-m5n250r2.txt txt = ./txt/cord-014464-m5n250r2.txt === reduce.pl bib === id = cord-355038-o2hr5mox author = nan title = Proceedings of Réanimation 2020, the French Intensive Care Society International Congress date = 2020-02-11 pages = extension = .txt mime = text/plain words = 102485 sentences = 7028 flesch = 52 summary = Conclusion: In patients with moderate-to-severe ARDS, a higher tidal volume under PSV within the 72 h following neuromuscular blockers cessation is independently associated with the 28-day mortality.Compliance with ethics regulations: Yes. Kaplan-Meier estimate of the cumulative probability of survival according to the mean tidal volume (Vt)-lower of higher than 8 ml/ kg-under pressure support ventilation (PSV) during the "transition period" transfusion is associated with adverse events, and equipoise remains on the optimal transfusion strategy in oncologic patients in surgical setting. Compliance with ethics regulations: Yes. Patients and methods: In a retrospective monocentric study (01/2013-01/2017) conducted in cardio-vascular surgical intensive care unit (ICU) in Henri Mondor teaching hospital, all consecutive adult patients who underwent peripheral VA-ECMO were included, with exclusion of those dying in the first 24 h. Compliance with ethics regulations: Yes. Rationale: Acute respiratory failure is the leading reason for intensive care unit (ICU) admission in immunocompromised patients and the need for invasive mechanical ventilation has become a major clinical end-point in randomized controlled trials (RCT). cache = ./cache/cord-355038-o2hr5mox.txt txt = ./txt/cord-355038-o2hr5mox.txt === reduce.pl bib === id = cord-005814-ak5pq312 author = nan title = 8th European Congress of Intensive Care Medicine Athens - Greece, October 18–22, 1995 Abstracts date = 1995 pages = extension = .txt mime = text/plain words = 179164 sentences = 12028 flesch = 56 summary = Results: In 5 patients with treated SS, 16 tests were performed (VL n=8; Dobu n=4; NA n=4 Method: Septic shock was defined as severe sepsis with either persistent hypotension (mean arterial pressure; MAP<70 mmHg) or the requirement for a noradrenaline (NA) infusion ~> 0.1 ~g/kg/min with a MAP _< 90mmHg. Cardiovascular support was limited to NA + dobutamine (DB), 546C88 was administered for up to 8 h at a fixed dose-rate of either i, 2.5, 5, 10 or 20 mg/kg/h iv. Methods: Fourteen cases were s~udied,their gestational age ranged from(27-32)ws.Continnous positive air way pressure was applied to six cases at Peep level from (3-6)cm H2o through nasal pronge,(group I),the other 8 cases were managed as routine,(group II).Blood gases, TcPO2,TcCo2,resp.rate,depth and pattern were monitored for assessment of tissue Oxygenation and ventilation, Results: Our rasults showed that early application of CPAP improve ventilation among (83.3%)of cases,while (16.7%)of cases need IMV.The cases of group II need IMV among (75%)of the studied cases during the second or the third day of life. cache = ./cache/cord-005814-ak5pq312.txt txt = ./txt/cord-005814-ak5pq312.txt === reduce.pl bib === id = cord-341063-3rqnu5bu author = nan title = 38th International Symposium on Intensive Care and Emergency Medicine: Brussels, Belgium. 20-23 March 2018 date = 2018-03-29 pages = extension = .txt mime = text/plain words = 98602 sentences = 6494 flesch = 52 summary = Procacitonin (PCT) emerges as a possible predictive tool in cardiothoracic intensive care unit (CTICU).We aim at testing the predictive power of PCT for early morbidity, prolonged ventilation, ICU and hospital stay, in patients developing early fever after cardiac surgery Methods: A retrospective descriptive study done in tertiary cardiac center, enrolling patients who stayed for more than 24 hours post-operatively in the CTICU Risk stratification included additive Euro score and PCT immunoluminometricaly prior to surgery and every 48 hours in response to onset of fever. Prognostic accuracy of quick sequential organ failure assessment (qSOFA) score for mortality: systematic review and meta-analysis Introduction: The purpose of this study was to summarize the evidence assessing the qSOFA [1] , calculated in admission of the patient in emergency department (ED) or intensive care unit (ICU), as a predictor of mortality. cache = ./cache/cord-341063-3rqnu5bu.txt txt = ./txt/cord-341063-3rqnu5bu.txt === reduce.pl bib === id = cord-010980-sizuef1v author = nan title = ECTES Abstracts 2020 date = 2020-05-11 pages = extension = .txt mime = text/plain words = 132644 sentences = 8727 flesch = 53 summary = We hypothesized that presentation to a PTC would yield increased mortality when subspecialty intervention was required and that this would be most pronounced at night when in-house attending coverage is absent at all state PTCs. Materials and methods: A review of the Pennsylvania Trauma Outcome Study (PTOS) database was performed to capture patients aged 12-18 who underwent any non-orthopedic trauma surgery. Traumatic subaxial cervical fractures: functional prognostic factors and survival analysis Introduction: The main goal of this study is to identify the risk factors for poor functional outcomes and to analyze the overall survival (OS) and complications rate in patients with traumatic cervical spinal cord injury (SCI) and subaxial cervical fracture (SACF) treated with open surgical fixation. After applying a multiple imputation on all the study variables, a logistic regression generalized estimating equation after adjustment for age, sex, mechanism of trauma, and the injury severity score as covariates and hospitals as a cluster assessed an association between quartile of patient volume in intensive care unit and hospital mortality. cache = ./cache/cord-010980-sizuef1v.txt txt = ./txt/cord-010980-sizuef1v.txt ===== Reducing email addresses cord-014538-6a2pviol cord-335975-m6lkrehi cord-355038-o2hr5mox Creating transaction Updating adr table ===== Reducing keywords cord-280348-vrnxucye cord-003011-vclnb0eh cord-003571-upogtny6 cord-261377-m5djp8mh cord-337098-33yj5g5v cord-298201-z68j0c63 cord-015651-yhi83hgq cord-337692-b89ow1mf cord-353895-tgn1kk07 cord-018834-4ligp4ak cord-294645-yzh8h7zo cord-000522-d498qj2b cord-015126-cyhcbk1j cord-306205-l42w2jyk cord-015082-l629n8is cord-293861-n6733nfd cord-027259-f4sgobcz cord-290295-gl144dh9 cord-273283-gb0m6fue cord-284332-p4c1fneh cord-014538-6a2pviol cord-003340-nqc1pduk cord-005777-6rvfsx4p cord-282660-9x937eus cord-269777-dm6te7nw cord-355892-9kkqmm6h cord-284786-pua14ogz cord-305936-tdswzj7r cord-314152-wd153s1g cord-005816-i54q5gsu cord-299613-5ju5fcf4 cord-351163-lyj94xn8 cord-335975-m6lkrehi cord-013338-0jlxuksk cord-352685-0ie6tkgm cord-294350-6veeygzp cord-003532-lcgeingz cord-005497-w81ysjf9 cord-014996-p6q0f37c cord-010980-sizuef1v cord-355038-o2hr5mox cord-014464-m5n250r2 cord-341063-3rqnu5bu cord-005814-ak5pq312 Creating transaction Updating wrd table ===== Reducing urls cord-003011-vclnb0eh cord-003571-upogtny6 cord-298201-z68j0c63 cord-294645-yzh8h7zo cord-000522-d498qj2b cord-027259-f4sgobcz cord-003340-nqc1pduk cord-273283-gb0m6fue cord-005777-6rvfsx4p cord-299613-5ju5fcf4 cord-352685-0ie6tkgm cord-014996-p6q0f37c cord-014464-m5n250r2 cord-010980-sizuef1v Creating transaction Updating url table ===== Reducing named entities cord-280348-vrnxucye cord-003011-vclnb0eh cord-003571-upogtny6 cord-261377-m5djp8mh cord-298201-z68j0c63 cord-337098-33yj5g5v cord-015651-yhi83hgq cord-337692-b89ow1mf cord-353895-tgn1kk07 cord-018834-4ligp4ak cord-294645-yzh8h7zo cord-000522-d498qj2b cord-306205-l42w2jyk cord-015126-cyhcbk1j cord-015082-l629n8is cord-027259-f4sgobcz cord-293861-n6733nfd cord-003340-nqc1pduk cord-290295-gl144dh9 cord-273283-gb0m6fue cord-282660-9x937eus cord-269777-dm6te7nw cord-284332-p4c1fneh cord-355892-9kkqmm6h cord-014538-6a2pviol cord-005777-6rvfsx4p cord-305936-tdswzj7r cord-284786-pua14ogz cord-314152-wd153s1g cord-299613-5ju5fcf4 cord-294350-6veeygzp cord-351163-lyj94xn8 cord-013338-0jlxuksk cord-352685-0ie6tkgm cord-005816-i54q5gsu cord-014996-p6q0f37c cord-341063-3rqnu5bu cord-003532-lcgeingz cord-005497-w81ysjf9 cord-014464-m5n250r2 cord-010980-sizuef1v cord-355038-o2hr5mox cord-335975-m6lkrehi cord-005814-ak5pq312 Creating transaction Updating ent table ===== Reducing parts of speech cord-280348-vrnxucye cord-003011-vclnb0eh cord-003571-upogtny6 cord-261377-m5djp8mh cord-337098-33yj5g5v cord-353895-tgn1kk07 cord-298201-z68j0c63 cord-337692-b89ow1mf cord-015651-yhi83hgq cord-018834-4ligp4ak cord-306205-l42w2jyk cord-294645-yzh8h7zo cord-000522-d498qj2b cord-027259-f4sgobcz cord-290295-gl144dh9 cord-293861-n6733nfd cord-003340-nqc1pduk cord-273283-gb0m6fue cord-284332-p4c1fneh cord-269777-dm6te7nw cord-282660-9x937eus cord-355892-9kkqmm6h cord-015082-l629n8is cord-305936-tdswzj7r cord-284786-pua14ogz cord-314152-wd153s1g cord-351163-lyj94xn8 cord-013338-0jlxuksk cord-294350-6veeygzp cord-299613-5ju5fcf4 cord-352685-0ie6tkgm cord-015126-cyhcbk1j cord-014538-6a2pviol cord-005777-6rvfsx4p cord-005816-i54q5gsu cord-003532-lcgeingz cord-335975-m6lkrehi cord-014996-p6q0f37c cord-014464-m5n250r2 cord-005497-w81ysjf9 cord-341063-3rqnu5bu cord-355038-o2hr5mox cord-010980-sizuef1v cord-005814-ak5pq312 Creating transaction Updating pos table Building ./etc/reader.txt cord-005497-w81ysjf9 cord-014996-p6q0f37c cord-005814-ak5pq312 cord-005497-w81ysjf9 cord-005814-ak5pq312 cord-014996-p6q0f37c number of items: 44 sum of words: 1,356,456 average size in words: 42,389 average readability score: 47 nouns: patients; mortality; study; results; group; care; methods; data; hospital; days; blood; treatment; time; patient; risk; age; analysis; cases; rate; years; sepsis; admission; injury; groups; introduction; trauma; score; ventilation; pressure; outcome; surgery; period; shock; failure; levels; therapy; day; conclusions; factors; hours; use; stay; level; infection; disease; studies; conclusion; ml; complications; lung verbs: used; included; associated; increased; compared; showed; performed; following; admitted; assessed; evaluated; found; receiving; requiring; measured; treated; reduce; identify; observed; related; improving; based; develop; determine; presented; undergo; reported; studied; decrease; according; collected; considered; predict; remains; defined; analyzed; inducing; provide; occur; need; died; obtain; investigate; suggested; lead; recording; make; describe; mean; conducted adjectives: clinical; acute; higher; severe; high; significant; respiratory; mean; septic; cardiac; intensive; first; non; medical; surgical; early; mechanical; pulmonary; lower; low; ill; different; renal; median; retrospective; arterial; prospective; total; positive; common; patient; abdominal; critical; primary; major; postoperative; new; initial; average; normal; important; specific; post; similar; fluid; negative; multiple; long; present; invasive adverbs: significantly; also; however; respectively; critically; well; often; statistically; even; therefore; especially; still; frequently; prior; mechanically; prospectively; less; retrospectively; least; previously; later; mainly; independently; particularly; clinically; recently; highly; commonly; usually; moreover; immediately; directly; finally; first; potentially; nt; furthermore; currently; severely; almost; rather; alone; successfully; randomly; mostly; already; better; initially; approximately; relatively pronouns: we; our; it; their; its; they; them; i; he; his; she; us; her; one; itself; you; themselves; your; him; my; me; himself; ours; s; em; rrt; p=0.0007; ≥151; ≥110; yourself; yhi83hgq; tv/; tnfrt; theirs; thee; t; sglt2-inhibitors; p~; pk/; p279; p.dligh]cine; ourselves; olhf).the; ol!guria; mrs; isap; ifitem; https://apps.dtic.mil/docs/citations/ada403148; hom'~; herself proper nouns: ICU; ARDS; II; Care; ±; CI; AKI; CT; Hospital; Fig; mg; C; APACHE; VAP; January; Intensive; COVID-19; ECMO; kg; University; Group; L; ED; PCT; MV; A; December; COPD; TBI; NIV; LPS; LOS; IQR; Table; T; S; SAPS; Unit; GCS; CO; B; IV; Department; Introduction; CONCLUSION; Critical; Medical; ICP; ISS; Emergency keywords: mortality; patient; study; icu; group; result; method; day; care; hospital; covid-19; ards; introduction; conclusion; vap; sofa; intensive; apache; aki; january; high; ecmo; university; peep; tbi; sepsis; score; pct; lps; iqr; treatment; table; saps; pandemic; niv; los; level; influenza; increase; gcs; critical; copd; cause; blood; acute; year; unit; trauma; surgery; respiratory one topic; one dimension: patients file(s): https://www.ncbi.nlm.nih.gov/pubmed/32720248/ titles(s): Pattern of comorbidities and 1-year mortality in elderly patients with COPD hospitalized in internal medicine wards: data from the RePoSI Registry three topics; one dimension: patients; patients; mortality file(s): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7223217/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225389/, https://api.elsevier.com/content/article/pii/S0014498320300838 titles(s): ECTES Abstracts 2020 | Proceedings of Réanimation 2017, the French Intensive Care Society International Congress | Disease, downturns, and wellbeing: Economic history and the long-run impacts of COVID-19 five topics; three dimensions: patients icu study; patients group mortality; patients trauma results; mortality patients fi; albumin hsa 2020 file(s): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092506/, https://www.ncbi.nlm.nih.gov/pubmed/20568833/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095784/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114985/, http://medrxiv.org/cgi/content/short/2020.06.10.20125005v1?rss=1 titles(s): 40th International Symposium on Intensive Care & Emergency Medicine: Brussels, Belgium. 24-27 March 2020 | Pharmacotherapy for Prevention and Treatment of Acute Respiratory Distress Syndrome: Current and Experimental Approaches | 10(th) European Congress of Trauma and Emergency Surgery: May 13–17, 2009 Antalya, Turkey | Social Disparities in the Evolution of an Epidemiological Profile: Transition Processes in Mortality Between 1971 and 2008 in an Industrialized Middle Income Country: The Case of Hungary | Estimating Lower Bounds for COVID-19 Mortality from Northern Italian Towns Type: cord title: keyword-mortality-cord date: 2021-05-25 time: 15:36 username: emorgan patron: Eric Morgan email: emorgan@nd.edu input: keywords:mortality ==== make-pages.sh htm files ==== make-pages.sh complex files ==== make-pages.sh named enities ==== making bibliographics id: cord-337098-33yj5g5v author: Agarwal, Shivani title: Preadmission Diabetes-Specific Risk Factors for Mortality in Hospitalized Patients With Diabetes and Coronavirus Disease 2019 date: 2020-08-07 words: 3625.0 sentences: 163.0 pages: flesch: 40.0 cache: ./cache/cord-337098-33yj5g5v.txt txt: ./txt/cord-337098-33yj5g5v.txt summary: OBJECTIVE: To examine whether HbA(1c), outpatient diabetes treatment regimen, demographics, and clinical characteristics are associated with mortality in hospitalized patients with diabetes and coronavirus disease 2019 (COVID-19). CONCLUSIONS: In this large U.S. cohort of hospitalized patients with diabetes and COVID-19, insulin treatment, as a possible proxy for diabetes duration, and obesity rather than long-term glycemic control were predictive of mortality. Few studies have specifically examined the effect of preadmission glycemic control in patients with diabetes and risk of in-hospital mortality from COVID-19, despite having great implications for outpatient glycemic management during the pandemic. The goal of this study was to use a U.S. cohort to examine the association of outpatient glycemic control, diabetes treatment, and other characteristics with mortality among hospitalized patients with diabetes and COVID-19. We investigated whether HbA 1c levels, outpatient diabetes treatment, and other characteristics were associated with in-hospital mortality among patients with COVID-19 and preexisting diabetes. abstract: OBJECTIVE: To examine whether HbA(1c), outpatient diabetes treatment regimen, demographics, and clinical characteristics are associated with mortality in hospitalized patients with diabetes and coronavirus disease 2019 (COVID-19). RESEARCH DESIGN AND METHODS: This was a retrospective cohort analysis of patients with diabetes hospitalized with confirmed COVID-19 infection from 11 March to 7 May 2020 at a large academic medical center in New York City. Multivariate modeling was used to assess the independent association of HbA(1c) levels and outpatient diabetes treatment regimen with mortality, in addition to independent effects of demographic and clinical characteristics. RESULTS: We included 1,126 hospitalized patients with diabetes and COVID-19 for analysis, among whom mean age was 68 years, 50% were male, 75% were Black, mean BMI was 30 kg/m(2), 98% had type 2 diabetes, mean HbA(1c) was 7.5%, and 33.1% died. HbA(1c) levels were not associated with mortality in unadjusted or adjusted analyses, but an outpatient regimen with any insulin treatment was strongly predictive. Additionally, age, sex, and BMI interacted such that in all age categories, mortality was higher with increasing BMI in males compared with females. CONCLUSIONS: In this large U.S. cohort of hospitalized patients with diabetes and COVID-19, insulin treatment, as a possible proxy for diabetes duration, and obesity rather than long-term glycemic control were predictive of mortality. Further investigation of underlying mechanisms of mortality and inpatient glycemic control is needed. url: https://www.ncbi.nlm.nih.gov/pubmed/32769128/ doi: 10.2337/dc20-1543 id: cord-273283-gb0m6fue author: Altschul, David J. title: A novel severity score to predict inpatient mortality in COVID-19 patients date: 2020-10-07 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: COVID-19 is commonly mild and self-limiting, but in a considerable portion of patients the disease is severe and fatal. Determining which patients are at high risk of severe illness or mortality is essential for appropriate clinical decision making. We propose a novel severity score specifically for COVID-19 to help predict disease severity and mortality. 4711 patients with confirmed SARS-CoV-2 infection were included. We derived a risk model using the first half of the cohort (n = 2355 patients) by logistic regression and bootstrapping methods. The discriminative power of the risk model was assessed by calculating the area under the receiver operating characteristic curves (AUC). The severity score was validated in a second half of 2356 patients. Mortality incidence was 26.4% in the derivation cohort and 22.4% in the validation cohort. A COVID-19 severity score ranging from 0 to 10, consisting of age, oxygen saturation, mean arterial pressure, blood urea nitrogen, C-Reactive protein, and the international normalized ratio was developed. A ROC curve analysis was performed in the derivation cohort achieved an AUC of 0.824 (95% CI 0.814–0.851) and an AUC of 0.798 (95% CI 0.789–0.818) in the validation cohort. Furthermore, based on the risk categorization the probability of mortality was 11.8%, 39% and 78% for patient with low (0–3), moderate (4–6) and high (7–10) COVID-19 severity score. This developed and validated novel COVID-19 severity score will aid physicians in predicting mortality during surge periods. url: https://www.ncbi.nlm.nih.gov/pubmed/33028914/ doi: 10.1038/s41598-020-73962-9 id: cord-280348-vrnxucye author: Argano, Christiano title: Pattern of comorbidities and 1-year mortality in elderly patients with COPD hospitalized in internal medicine wards: data from the RePoSI Registry date: 2020-07-27 words: 4641.0 sentences: 257.0 pages: flesch: 39.0 cache: ./cache/cord-280348-vrnxucye.txt txt: ./txt/cord-280348-vrnxucye.txt summary: Chronic obstructive pulmonary disease (COPD) represents an important leading cause of morbidity and mortality with high economic and social costs: according to the WHO, COPD is the fourth most common cause of death worldwide, and it is estimated to be the third by 2020; furthermore, the global burden of COPD is expected to increase in the coming years, due to the prevalence of smoking and aging of the world population [1] . The following clinical characteristics were evaluated: respiratory and non-respiratory disease distribution at hospital admission (according to International Classification of Diseases-Ninth Revision); cognitive status and mood disorders (by the Short-Blessed-Test [SBT] [9] and the Geriatric-Depression-Scale [GDS] [10] ,respectively; performance in activities of daily living at hospital admission (measured by means of the Barthel Index [BI] [11] ; severity and comorbidity index(assessed by the Cumulative-Illness-Rating-Scale CIRS-s and CIRS-c, respectively) [12] , glomerular filtration rate (using the Chronic Kidney Disease Epidemiology Collaboration-formula [13] ), length of hospital stay, drugs prescriptions (at admission, discharge, at 3 and 12 months follow-up), destination at discharge, in-hospital and 3-month and 1-year mortality rate. abstract: Currently, chronic obstructive pulmonary disease (COPD) represents the fourth cause of death worldwide with significant economic burden. Comorbidities increase in number and severity with age and are identified as important determinants that influence the prognosis. In this observational study, we retrospectively analyzed data collected from the RePoSI register. We aimed to investigate comorbidities and outcomes in a cohort of hospitalized elderly patients with the clinical diagnosis of COPD. Socio-demographic, clinical characteristics and laboratory findings were considered. The association between variables and in-hospital, 3-month and 1-year follow-up were analyzed. Among 4696 in-patients, 932 (19.8%) had a diagnosis of COPD. Patients with COPD had more hospitalization, a significant overt cognitive impairment, a clinically significant disability and more depression in comparison with non-COPD subjects. COPD patients took more drugs, both at admission, in-hospital stay, discharge and 3-month and 1-year follow-up. 14 comorbidities were more frequent in COPD patients. Cerebrovascular disease was an independent predictor of in-hospital mortality. At 3-month follow-up, male sex and hepatic cirrhosis were independently associated with mortality. ICS-LABA therapy was predictor of mortality at in-hospital, 3-month and 1-year follow-up. This analysis showed the severity of impact of COPD and its comorbidities in the real life of internal medicine and geriatric wards. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s11739-020-02412-1) contains supplementary material, which is available to authorized users. url: https://www.ncbi.nlm.nih.gov/pubmed/32720248/ doi: 10.1007/s11739-020-02412-1 id: cord-299613-5ju5fcf4 author: Arthi, Vellore title: Disease, downturns, and wellbeing: Economic history and the long-run impacts of COVID-19 date: 2020-11-03 words: 17509.0 sentences: 810.0 pages: flesch: 48.0 cache: ./cache/cord-299613-5ju5fcf4.txt txt: ./txt/cord-299613-5ju5fcf4.txt summary: In this paper, we review the evidence on the long-run effects on health, labor, and human capital of both historical pandemics (with a focus on the 1918 Influenza Pandemic) and historical recessions (with a focus on the Great Depression). Thus, a historical perspective allows us to use rich data to look at not only the short-term effects of crises like COVID-19 on health, labor, and human capital, but also the long-term and intergenerational impacts along these dimensions for both individuals and the wider economy. To examine how history can inform our view of the coronavirus pandemic and associated policy responses as they relate to long-run wellbeing, we begin in Section II by reviewing the features of COVID-19 that will determine its potential health and economic impacts, and placing these features in historical context. abstract: How might COVID-19 affect human capital and wellbeing in the long run? The COVID-19 pandemic has already imposed a heavy human cost—taken together, this public health crisis and its attendant economic downturn appear poised to dwarf the scope, scale, and disruptiveness of most modern pandemics. What evidence we do have about other modern pandemics is largely limited to short-run impacts. Consequently, recent experience can do little to help us anticipate and respond to COVID-19’s potential long-run impact on individuals over decades and even generations. History, however, offers a solution. Historical crises offer closer analogues to COVID-19 in each of its key dimensions—as a global pandemic, as a global recession—and offer the runway necessary to study the life-course and intergenerational outcomes. In this paper, we review the evidence on the long-run effects on health, labor, and human capital of both historical pandemics (with a focus on the 1918 Influenza Pandemic) and historical recessions (with a focus on the Great Depression). We conclude by discussing how past crises can inform our approach to COVID-19—helping tell us what to look for, what to prepare for, and what data we ought to collect now. url: https://api.elsevier.com/content/article/pii/S0014498320300838 doi: 10.1016/j.eeh.2020.101381 id: cord-284332-p4c1fneh author: Bosma, Karen J. title: Pharmacotherapy for Prevention and Treatment of Acute Respiratory Distress Syndrome: Current and Experimental Approaches date: 2012-09-19 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: The acute respiratory distress syndrome (ARDS) arises from direct and indirect injury to the lungs and results in a life-threatening form of respiratory failure in a heterogeneous, critically ill patient population. Critical care technologies used to support patients with ARDS, including strategies for mechanical ventilation, have resulted in improved outcomes in the last decade. However, there is still a need for effective pharmacotherapies to treat ARDS, as mortality rates remain high. To date, no single pharmacotherapy has proven effective in decreasing mortality in adult patients with ARDS, although exogenous surfactant replacement has been shown to reduce mortality in the paediatric population with ARDS from direct causes. Several promising therapies are currently being investigated in preclinical and clinical trials for treatment of ARDS in its acute and subacute, exudative phases. These include exogenous surfactant therapy, β(2)-adrenergic receptor agonists, antioxidants, immunomodulating agents and HMG-CoA reductase inhibitors (statins). Recent research has also focused on prevention of acute lung injury and acute respiratory distress in patients at risk. Drugs such as captopril, rosiglitazone and incyclinide (COL-3), a tetracycline derivative, have shown promising results in animal models, but have not yet been tested clinically. Further research is needed to discover therapies to treat ARDS in its late, fibroproliferative phase. Given the vast number of negative clinical trials to date, it is unlikely that a single pharmacotherapy will effectively treat all patients with ARDS from differing causes. Future randomized controlled trials should target specific, more homogeneous subgroups of patients for single or combination therapy. url: https://www.ncbi.nlm.nih.gov/pubmed/20568833/ doi: 10.2165/10898570-000000000-00000 id: cord-284786-pua14ogz author: Coker, Eric S. title: The Effects of Air Pollution on COVID-19 Related Mortality in Northern Italy date: 2020-08-04 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: Long-term exposure to ambient air pollutant concentrations is known to cause chronic lung inflammation, a condition that may promote increased severity of COVID-19 syndrome caused by the novel coronavirus (SARS-CoV-2). In this paper, we empirically investigate the ecologic association between long-term concentrations of area-level fine particulate matter (PM(2.5)) and excess deaths in the first quarter of 2020 in municipalities of Northern Italy. The study accounts for potentially spatial confounding factors related to urbanization that may have influenced the spreading of SARS-CoV-2 and related COVID-19 mortality. Our epidemiological analysis uses geographical information (e.g., municipalities) and negative binomial regression to assess whether both ambient PM(2.5) concentration and excess mortality have a similar spatial distribution. Our analysis suggests a positive association of ambient PM(2.5) concentration on excess mortality in Northern Italy related to the COVID-19 epidemic. Our estimates suggest that a one-unit increase in PM(2.5) concentration (µg/m(3)) is associated with a 9% (95% confidence interval: 6–12%) increase in COVID-19 related mortality. url: https://www.ncbi.nlm.nih.gov/pubmed/32836855/ doi: 10.1007/s10640-020-00486-1 id: cord-352685-0ie6tkgm author: Coleman, T. S. title: Estimating Lower Bounds for COVID-19 Mortality from Northern Italian Towns date: 2020-06-12 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: For COVID-19 the Infection Fatality Rate or IFR - a crucial variable in epidemiological modeling - is difficult to estimate because many cases are asymptomatic and the overall infection rate is generally not known. Circumstances in the Italian provinces of Milano, Bergamo, Brescia, and Lodi allow estimation of lower bounds for age- and sex-specific all-cause excess mortality (a proxy for IFR) since anecdotal reports indicate some towns were close to fully infected. Using data from ISTAT on mortality from January 1 through April 15 for 2020 and the three preceding years, I estimate excess mortality by sex and age categories (0-14, 15-54, 55-64, 65-74, and 75+ years) while controlling for town-specific mortality that proxies for town-specific infection rate. The 99th percentile from the tail of the town distribution gives a lower-bound estimate for COVID-19 mortality. The overall population-weighted mortality at the 99th percentile is 1.09 percent (95% CI 1.06-1.14). The age- and sex-specific rates vary considerably: for men age 65-74 the estimate is 2.10 percent (95% CI 1.94-2.28) which is 3.5-times higher than men 55-64 and 2.7-times higher than women 65-74. url: http://medrxiv.org/cgi/content/short/2020.06.10.20125005v1?rss=1 doi: 10.1101/2020.06.10.20125005 id: cord-003340-nqc1pduk author: Dahal, Sushma title: Natality Decline and Spatial Variation in Excess Death Rates During the 1918–1920 Influenza Pandemic in Arizona, United States date: 2018-07-26 words: 3326.0 sentences: 167.0 pages: flesch: 49.0 cache: ./cache/cord-003340-nqc1pduk.txt txt: ./txt/cord-003340-nqc1pduk.txt summary: title: Natality Decline and Spatial Variation in Excess Death Rates During the 1918–1920 Influenza Pandemic in Arizona, United States Moreover, excess mortality rates were highest in northern Arizona counties, where Native Americans were historically concentrated, suggesting a link between ethnic and/or sociodemographic factors and risk of pandemic-related death. Moreover, excess mortality rates were highest in northern Arizona counties, where Native Americans were historically concentrated, suggesting a link between ethnic and/or sociodemographic factors and risk of pandemic-related death. We also analyzed 21,334 individual birth certificates to quantify the impact of the 1918-1920 influenza pandemic on natality fluctuations in Maricopa county, the most populous county in Arizona state. Likewise, our results suggest that northern counties in Arizona with high Native American population density (e.g., Apache, Coconino, and Navajo) experienced higher excess pandemic death rates compared with other counties in the state. abstract: A large body of epidemiologic research has concentrated on the 1918 influenza pandemic, but more work is needed to understand spatial variation in pandemic mortality and its effects on natality. We collected and analyzed 35,151 death records from Arizona for 1915–1921 and 21,334 birth records from Maricopa county for 1915–1925. We estimated the number of excess deaths and births before, during, and after the pandemic period, and we found a significant decline in the number of births occurring 9–11 months after peak pandemic mortality. Moreover, excess mortality rates were highest in northern Arizona counties, where Native Americans were historically concentrated, suggesting a link between ethnic and/or sociodemographic factors and risk of pandemic-related death. The relationship between birth patterns and pandemic mortality risk should be further studied at different spatial scales and in different ethnic groups. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269250/ doi: 10.1093/aje/kwy146 id: cord-013338-0jlxuksk author: Duong, William title: An increasing trend in geriatric trauma patients undergoing surgical stabilization of rib fractures date: 2020-10-23 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: PURPOSE: The proportion of geriatric trauma patients (GTPs) (age ≥ 65 years old) with chest wall injury undergoing surgical stabilization of rib fractures (SSRF) nationally is unknown. We hypothesize a growing trend of GTPs undergoing SSRF, and sought to evaluate risk of respiratory complications and mortality for GTPs compared to younger adults (18–64 years old) undergoing SSRF. METHODS: The Trauma Quality Improvement Program (2010–2016) was queried for patients with rib fracture(s) who underwent SSRF. GTPs were compared to younger adults. A multivariable logistic regression analysis was performed. RESULTS: From 21,517 patients undergoing SSRF, 3,001 (16.2%) were GTPs. Of all patients undergoing SSRF in 2010, 10.6% occurred on GTPs increasing to 17.9% in 2016 (p < 0.001) with a geometric-mean-annual increase of 11.5%. GTPs had a lower median injury severity score (18 vs. 22, p < 0.001), but had a higher rate of mortality (4.7% vs. 1.2%, p < 0.001). After controlling for covariates, GTPs had an increased associated risk of mortality (OR 4.80, CI 3.62–6.36, p < 0.001). On a separate multivariate analysis for all trauma patients with isolated chest Abbreviated Injury Scale 3, GTPs were associated with a similar four-fold risk of mortality (OR 4.21, CI 1.98–6.32, p < 0.001). CONCLUSION: Spanning 7 years of data, the proportion of GTPs undergoing SSRF increased by over 7%. Although GTPs undergoing SSRF had lesser injuries, their risk of mortality was four times higher than other adult trauma patients undergoing SSRF, which was similar to their increased background risk of mortality. Ultimately, SSRF in GTPs should be considered on an individualized basis with careful attention to risk–benefit ratio. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s00068-020-01526-7) contains supplementary material, which is available to authorized users. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583690/ doi: 10.1007/s00068-020-01526-7 id: cord-018834-4ligp4ak author: Farag, Ehab title: The Perioperative Use of Albumin date: 2016-06-23 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: Human serum albumin (HSA) is the predominant product of hepatic protein synthesis and one of the more abundant plasma proteins. HSA is a monomeric multidomain macromolecule, representing the main determinant of plasma oncotic pressure and the main modulator of fluid distribution between body compartments. HSA displays an essential role in maintaining the integrity of the vascular barrier. HSA is the most important antioxidant capacity of human plasma, in addition to its ability to protect the body from the harmful effects of heavy metals such as iron and copper and reduce their ability to produce reactive oxygen radicals. HSA is the main depot for nitric oxide (NO) transport in the blood. HSA represents the main carrier for fatty acids, affects pharmacokinetics of many drugs, and provides the metabolic modification of some drugs and displays pseudo-enzymatic properties. HSA has been widely used successfully for more than 50 years in many settings of perioperative medicine including hypovolemia, shock, burns, surgical blood loss, sepsis, and acute respiratory distress syndrome (ARDS). Recently, the use of HSA has shown a promising neuroprotective effect in patients with subarachnoid hemorrhage. The most recent evidence-based functions and uses of HSA in the perioperative period are reviewed in this chapter. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7123816/ doi: 10.1007/978-3-319-39141-0_9 id: cord-294645-yzh8h7zo author: Freeman, David W. title: Association between GDF15, poverty and mortality in urban middle-aged African American and white adults date: 2020-08-07 words: 4977.0 sentences: 221.0 pages: flesch: 43.0 cache: ./cache/cord-294645-yzh8h7zo.txt txt: ./txt/cord-294645-yzh8h7zo.txt summary: Multivariable adjusted Cox regression models were used to assess the association between log-transformed GDF15 (logGDF15) and 12-year mortality outcomes (all-cause, cardiovascularand cancer-specific outcomes) and interactions with sex, race and poverty status. The objectives of the present study were to assess the association between serum GDF15 and all-cause and cause-specific mortality, and to identify interactions between GDF15 and sex, race and poverty status in a large cohort of community-based middle-aged adults recruited from Baltimore, Maryland. In a community-dwelling cohort of younger urban adults (mean age 49.6) with diverse racial and socioeconomic status, we found that elevated serum GDF15 level was strongly associated with all-cause mortality, CVD-and cancer-specific mortality risk. Our findings of increased risk of mortality due to all-causes and CVD and elevated GDF15 levels in a diverse cohort are consistent with results of previous studies conducted in apparently healthy, community-dwelling adults [12-15, 17, 18] . abstract: Mortality disparities are influenced by race and poverty. There is limited information about whether poverty influences biologic markers of mortality risk. Emerging data suggests that growth differentiation factor 15 (GDF15) is associated with mortality; however, the interplay between GDF15, sociodemographic factors and mortality is not known. We sought to evaluate the interactions between GDF15 and sex, race and poverty status on mortality. Serum GDF15 was measured in 1036 African American and white middle-aged men and women above and below 125% of the Federal poverty status from the Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS) study. Multivariable adjusted Cox regression models were used to assess the association between log-transformed GDF15 (logGDF15) and 12-year mortality outcomes (all-cause, cardiovascular- and cancer-specific outcomes) and interactions with sex, race and poverty status. Likelihood ratio tests were used to assess significance of the interaction terms. Median GDF15 was 655.2 pg/mL (IQR = 575.1). During 12.2 years of follow-up, 331 died of which 94 cardiovascular- and 87 were cancer-specific deaths. One unit of increase in logGDF15 was associated with a hazard ratio for all-cause mortality, cardiovascular- and cancer-specific mortality of 2.26 (95% confidence interval [CI], 1.94–2.64), 2.74 (95%CI, 2.06–3.63) and 1.41 (95%CI, 1.00–2.00), respectively. There was an interaction between logGDF15 and poverty status on all-cause mortality (p<0.05). The GDF15×poverty status interaction term improved model calibration for all-cause mortality. Our study provides the first evidence that the effect of elevated GDF15 on all-cause mortality is modified by poverty status. url: https://www.ncbi.nlm.nih.gov/pubmed/32764826/ doi: 10.1371/journal.pone.0237059 id: cord-305936-tdswzj7r author: Freitas, André Ricardo Ribas title: Excess of Mortality in Adults and Elderly and Circulation of Subtypes of Influenza Virus in Southern Brazil date: 2018-01-08 words: 4343.0 sentences: 193.0 pages: flesch: 39.0 cache: ./cache/cord-305936-tdswzj7r.txt txt: ./txt/cord-305936-tdswzj7r.txt summary: Despite not controlling for comorbidities, climate, and vaccination, for the >70 years, ratio of respiratory diseases excess mortality rates between AH1N1 (2009) and severe year of H3N2 (2007) shows protection in the pandemic year and great vulnerability during AH3N2 virus predominance. We analyzed particularly the most predominant variants (AH1N1 and AH3N2) on excess of mortality in the adults and elderly of different age groups in a region with marked seasonality of respiratory diseases in Brazil. Among adults (24-59 years), we observe a large excess of deaths rates during the 2009 pandemic (953 obits), which correspond to 7.1 excess deaths from all causes, and 99 excess mortality from respiratory diseases associated with viral infection in every 100,000 individuals of the age group. Although the elderly are the most vulnerable group to viral respiratory infections, we found relative small excess of deaths in years of circulating AH1N1 pre pandemic (2002 and 2008) . abstract: PURPOSE: In the elderly population, the influenza infection and its clinical complications are important causes of hospitalization and death, particularly, in longer-lived age. The objective of this study is to analyze the impact of influenza virus circulation on mortality in the elderly and adults, in years with different predominant virus strains. METHODS: We performed a time trend study to evaluated excess of mortality for pneumonia and influenza, respiratory disease, and all-causes in southern region of Brazil, from 2002 to 2015. After considering other models, we opted for Serfling regression. Excess of death rates per 100,000 inhabitants were analyzed in specific age groups (24–59, 60–69, 70–79, ≥80 years) and by year of occurrence. Mortality information were taken from Brazilian Mortality Information System and etiological data were accessed in Sentinel Virological Surveillance database, getting the weekly positivity of the immunofluorescence tests for influenza A (H1N1, H3N2), and B. RESULTS: In southern Brazil, there is an evident seasonal pattern of all death outcomes among different age groups in the dry and cold season (April–September). The highest excess mortality rates occurs among older, particularly in years of circulation of influenza AH3N2, especially among people ≥80 years, in 2003 and 2007—years of great severity of influenza activity. After 2009, with the introduction of the pandemic influenza AH1N1, we observed a lower impact on the mortality of the elderly compared to <60 years. DISCUSSION: A cross reactivity antibody response from past exposure probably provided protection against disease in the elderly. Despite not controlling for comorbidities, climate, and vaccination, for the >70 years, ratio of respiratory diseases excess mortality rates between AH1N1 (2009) and severe year of H3N2 (2007) shows protection in the pandemic year and great vulnerability during AH3N2 virus predominance. CONCLUSION: The reduced immune response to infection, and to vaccination, and presence of comorbidities recommend a special attention to this age group in Brazil. Besides medical assistance, the timeliness of vaccine campaigns, its composition, and etiological surveillance of respiratory diseases are some of the preventive and public health measures. url: https://doi.org/10.3389/fimmu.2017.01903 doi: 10.3389/fimmu.2017.01903 id: cord-261377-m5djp8mh author: Grech, Victor title: COVID-19 and potential global mortality - Revisited date: 2020-04-30 words: 389.0 sentences: 34.0 pages: flesch: 63.0 cache: ./cache/cord-261377-m5djp8mh.txt txt: ./txt/cord-261377-m5djp8mh.txt summary: title: COVID-19 and potential global mortality Revisited (1) In a previous paper,(2) this author attempted to assess potential COVID-19 continent-based mortality based on initial WHO data from China which estimated that 14% of infected cases are severe and require hospitalisation, 5% of infected cases are very severe and require intensive care admission, mostly for ventilation, and 4% of infected die. For this reason, the table in the initial paper showing continent and global estimates (2) has been recalculated with a correction factor, an estimated 10% symptomatic proportion of infected individuals. Clearly, this pandemic has the potential to be as severe in terms of mortality as the influenza pandemic of 1918 which killed more than 50 million people and caused more than 500 million infections worldwide.(5) The conclusions of the previous paper stand. Unknown unknowns -COVID-19 and potential global mortality abstract: nan url: https://www.ncbi.nlm.nih.gov/pubmed/32387001/ doi: 10.1016/j.earlhumdev.2020.105054 id: cord-293861-n6733nfd author: Juhász, Attila title: Antithrombotic Preventive Medication Prescription Redemption and Socioeconomic Status in Hungary in 2016: A Cross-Sectional Study date: 2020-09-19 words: 6067.0 sentences: 245.0 pages: flesch: 32.0 cache: ./cache/cord-293861-n6733nfd.txt txt: ./txt/cord-293861-n6733nfd.txt summary: Risk analysis capabilities were applied to estimate the relationships between socioeconomic status, which was characterized by quintiles of a multidimensional composite indicator (deprivation index), and mortality due to thromboembolic diseases as well as antithrombotic medications for the year 2016 at the district level in Hungary. Although data on the level and availability of secondary prevention at the country level would be essential for planning and targeting national health system policies that can decrease premature CVD mortality and morbidity, only a few studies have been published on the link between the utilization of antiplatelet drugs and anticoagulants (hereafter antithrombotic agents) for preventive purposes and socioeconomic status. Since physicians in general practice play a major role in initiating, coordinating, and providing long-term follow-up for the prevention of non-communicable diseases [23] , our study examined the prescription and redemption rates of the most common oral antiplatelet drugs and anticoagulants prescribed for thrombosis prevention from all general practices and defined their relationships with socioeconomic status in Hungary. abstract: This work was designed to investigate antithrombotic drug utilization and its link with the socioeconomic characteristics of specific population groups in Hungary by a comparative analysis of data for prescriptions by general practitioners and the redeemed prescriptions for antithrombotic drugs. Risk analysis capabilities were applied to estimate the relationships between socioeconomic status, which was characterized by quintiles of a multidimensional composite indicator (deprivation index), and mortality due to thromboembolic diseases as well as antithrombotic medications for the year 2016 at the district level in Hungary. According to our findings, although deprivation is a significant determinant of mortality due to thromboembolic diseases, clusters can be identified that represent exemptions to this rule: an eastern part of Hungary, consisting of two highly deprived counties, had significantly lower mortality than the country average; by contrast, the least-deprived northwestern part of the country, consisting of five counties, had significantly higher mortality than the country average. The fact that low socioeconomic status in general and poor adherence to antithrombotic drugs irrespective of socioeconomic status were associated with increased mortality indicates the importance of more efficient control of preventive medication and access to healthcare in all districts of the country to reduce mortality due to thromboembolic diseases. url: https://www.ncbi.nlm.nih.gov/pubmed/32961765/ doi: 10.3390/ijerph17186855 id: cord-014538-6a2pviol author: Kamilia, Chtara title: Proceedings of Réanimation 2017, the French Intensive Care Society International Congress date: 2017-01-10 words: 61068.0 sentences: 3463.0 pages: flesch: 49.0 cache: ./cache/cord-014538-6a2pviol.txt txt: ./txt/cord-014538-6a2pviol.txt summary: Other parameters that were significantly different between the patients who died and those who survived were an advanced age, an elevated IGS II score at hospital admission, an elevated SOFA score at study entry, a late healthcare-associated infection and several biological variables: a high C reactive protein, low albumin and prealbumin and a poor percent of monocytes expressing HLA-DR, all measured at day 7. Parameters collected were demographic features, comorbidities, regular treatment, dyspnea assessed by the MRC scale, initial clinical severity reflected by SAPS II and APACHE II scores, modalities and ICU admission deadlines, initial arterial blood gas analysis, management of patients in the ICU (ventilation modalities, prescription of antibiotics, use of vasoactive drugs) and their outcomes (incidence of nosocomial infections and their sites, length of stay and ICU mortality). abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225389/ doi: 10.1186/s13613-016-0224-7 id: cord-353895-tgn1kk07 author: Kavanagh, Matthew M title: Reckoning with mortality: global health, HIV, and the politics of data date: 2020-07-03 words: 1848.0 sentences: 94.0 pages: flesch: 46.0 cache: ./cache/cord-353895-tgn1kk07.txt txt: ./txt/cord-353895-tgn1kk07.txt summary: Studies in South Africa, Kenya, Zambia, and the Democratic Republic of the Congo have shown that most patients with HIV admitted to hospital have already been on antiretroviral therapy (often for years) but they either stop treatment or are on a treatment regimen that is not effectively suppressing the virus. In South Africa, in particular, tracking the mortality of young people using systems at the local level helped monitor the effectiveness of HIV programmes. 20 Hopefully, this step will improve patient outcomes by incentivising effective interventions for advanced HIV disease and support for people who have stopped treatment to re-enter care. 17 Third, we can move towards a variety of outcomeoriented global health programmes beyond HIV, for which measures of success move from the number of patients receiving services to explicit reductions in mortality rates. abstract: nan url: https://www.sciencedirect.com/science/article/pii/S0140673620310461 doi: 10.1016/s0140-6736(20)31046-1 id: cord-015651-yhi83hgq author: Kovács, Katalin title: Social Disparities in the Evolution of an Epidemiological Profile: Transition Processes in Mortality Between 1971 and 2008 in an Industrialized Middle Income Country: The Case of Hungary date: 2014-03-25 words: 11309.0 sentences: 512.0 pages: flesch: 48.0 cache: ./cache/cord-015651-yhi83hgq.txt txt: ./txt/cord-015651-yhi83hgq.txt summary: One of main conclusions has been that they have not so far undergone the healthier life style changes that have occurred in Western Europe, and this has resulted in a "reversed epidemiological transition", in which an elevated burden of cardiovascular diseases dominates the pattern of mortality (Vallin and Meslé 2004) . In this paper I shall review recent developments in epidemiological transition theory, and test the applicability of some of these theories to the evolution of cause-and education-specific mortality inequalities in Hungary between 1971 and 2008. Omran, starting from his very first publication, continuously mentioned social disparities in mortality as well as the driving forces listed above but he did not provide a theoretical framework for the application of these in connection with particular mortality or disease patterns specific for single countries or population sub-groups. abstract: The present paper seeks to understand the transformation of mortality patterns in Hungary, by which mortality inequalities by education began to appear in the early 1980s, continued to grow in the following 25 years, and now seem to be stabilising. The first part of this paper overviews the theoretical innovations of the last decades regarding the interpretation of cause-specific mortality dynamics, often referred to as epidemiological transition theories, and their relevance for the analysis of mortality inequalities. The paper then analyses the cause-specific trends of mortality for two educational classes between 1971 and 2008. The trends were corrected for changes in the coding system and divided into linear (stagnating, increasing or decreasing) periods. Causes of death were grouped according to the relationship between the sequences of these periods for the two educational classes. The 57 causes of death were finally clustered into six groups. One group, which is dominated by nutrition-related and cardiovascular diseases, is largely responsible for the onset of mortality inequalities in 1980. The results imply that the quality of nutrition has diverged for the educational classes since 1980, and this fact has left its footprint on the pattern of mortality. The history of food production and availability seems to be in line with nutrition-related mortality, and it is argued that nutrition transition theory provides a very plausible explanatory framework for the growth of mortality inequalities. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114985/ doi: 10.1007/978-3-319-03029-6_4 id: cord-290295-gl144dh9 author: Martínez-López, Joaquín title: Multiple myeloma and SARS-CoV-2 infection: clinical characteristics and prognostic factors of inpatient mortality date: 2020-10-19 words: 4086.0 sentences: 186.0 pages: flesch: 36.0 cache: ./cache/cord-290295-gl144dh9.txt txt: ./txt/cord-290295-gl144dh9.txt summary: Among MM patients, inpatient mortality was 41% in males, 42% in patients aged >65 years, 49% in patients with active/progressive MM at hospitalization, and 59% in patients with comorbid renal disease at hospitalization, which were independent prognostic factors on adjusted multivariate analysis. There are cumulative data indicating that patients with cancer may be at increased risk for more severe COVID-19 and associated complications, including those receiving or not receiving treatment within the month prior to infection 5, 6 , although other recent results suggest mortality may be primarily associated with age, male sex, and comorbidities 7 . To our knowledge, this is the first large case-series study to describe comprehensively the clinical characteristics of COVID-19 in hospitalized MM patients, compare outcomes with a noncancer cohort of COVID-19 patients, and identify preadmission prognostic factors of inpatient mortality. abstract: There is limited information on the characteristics, prognostic factors, and outcomes of patients with multiple myeloma (MM) hospitalized with COVID-19. This retrospective case series investigated 167 patients reported from 73 hospitals within the Spanish Myeloma Collaborative Group network in March and April, 2020. Outcomes were compared with 167 randomly selected, contemporary, age-/sex-matched noncancer patients with COVID-19 admitted at six participating hospitals. Among MM and noncancer patients, median age was 71 years, and 57% of patients were male; 75 and 77% of patients, respectively, had at least one comorbidity. COVID-19 clinical severity was moderate–severe in 77 and 89% of patients and critical in 8 and 4%, respectively. Supplemental oxygen was required by 47 and 55% of MM and noncancer patients, respectively, and 21%/9% vs 8%/6% required noninvasive/invasive ventilation. Inpatient mortality was 34 and 23% in MM and noncancer patients, respectively. Among MM patients, inpatient mortality was 41% in males, 42% in patients aged >65 years, 49% in patients with active/progressive MM at hospitalization, and 59% in patients with comorbid renal disease at hospitalization, which were independent prognostic factors on adjusted multivariate analysis. This case series demonstrates the increased risk and identifies predictors of inpatient mortality among MM patients hospitalized with COVID-19. url: https://doi.org/10.1038/s41408-020-00372-5 doi: 10.1038/s41408-020-00372-5 id: cord-027259-f4sgobcz author: Metsker, Oleg title: Stroke ICU Patient Mortality Day Prediction date: 2020-05-23 words: 5328.0 sentences: 204.0 pages: flesch: 42.0 cache: ./cache/cord-027259-f4sgobcz.txt txt: ./txt/cord-027259-f4sgobcz.txt summary: On the basis of the analysis of 12 modern prognostic models from 10 countries we can identify some of the most stable (main) predictors for the causes of intra-hospital mortality: age [16, [20] [21] [22] [23] [24] ; type of stroke [25] ; lesion location [25] ; level of consciousness [11, 20, 23, 25, 26] upon admission; NIHSS stroke severity [10, 21, 22, 24] ; comorbidity [22, 27] , Charlson comorbidity index [23] , Atrial fibrillation [11, 22] , case history Transitor ischemic attack (TIA) [31]; hospital complications (high intracranial pressure) [16] , pneumonia, seizures, anxiety/depression, infections, limb pains and constipation [22, 27] . Early mortality in each subgroup was associated with a number of demographic, clinical, and instrumental-laboratory characteristics based on the interpretation of the results of calculating the significance of predictors of binary classification models by machine learning methods from the Scikit-Learn library 2 . abstract: This article presents a study on development of methods for analysis of data reflecting the process of treatment of stroke inpatients to predict clinical outcomes at the emergency care unit. The aim of this work is to develop models for the creation of validated risk scales for early intravenous stroke with minimum number of parameters with maximum prognostic accuracy and possibility to calculate the time of “expected intravenous stroke mortality”. The study of experience in the development and use of medical information systems allows us to state the insufficient ability of existing models for adequate data analysis, weak formalization and lack of system approach in the collection of diagnostic data, insufficient personalization of diagnostic data on the factors determining early intravenous stroke mortality. In our study we divided patients into 3 subgroups according to the time of death - up to 1 day, 1 to 3 days, and 4 to 10 days. Early mortality in each subgroup was associated with a number of demographic, clinical, and instrumental-laboratory characteristics based on the interpretation of the results of calculating the significance of predictors of binary classification models by machine learning methods from the Scikit-Learn library. The target classes in training were “mortality rate of 1 day”, “mortality rate of 1–3 days”, “mortality rate from 4 days”. AUC ROC of trained models reached 91% for the method of random forest. The results of interpretation of decision trees and calculation of significance of predictors of built-in methods of random forest coincide that can prove to correctness of calculations. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303676/ doi: 10.1007/978-3-030-50423-6_29 id: cord-355892-9kkqmm6h author: Miller, Larry E. title: Diabetes mellitus increases the risk of hospital mortality in patients with Covid-19: Systematic review with meta-analysis date: 2020-10-02 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: BACKGROUND: The mortality rate associated with Covid-19 varies considerably among studies and determinants of this variability are not well characterized. METHODS: A systematic review of peer-reviewed literature published through March 31, 2020 was performed to estimate the mortality rate among hospitalized patients in China with a confirmed diagnosis of Covid-19. Hospital mortality rates were estimated using an inverse variance-weighted random-effects meta-analysis model. Funnel plot symmetry was evaluated for small-study effects, a one-study removed sensitivity analysis assessed the influence of individual studies on the pooled mortality rate, and metaregression assessed the association of potential confounding variables with mortality rates. RESULTS: The review included 16 observational studies involving 1832 hospitalized patients with a diagnosis of Covid-19. The surveillance period among studies ranged from December 16, 2019 to February 23, 2020. The median patient age was 53 years and 53% were males. A total of 38.5% of patients presented with at least 1 comorbidity, most commonly hypertension (24.0%), cardiac disease (15.1%), and diabetes mellitus (14.4%). Fever and cough, reported in 84.8% and 61.7% of patients respectively, were the most common patient symptoms. The pooled mortality rate was 9.9% (95% confidence interval 6.1% to 14.5%). Funnel plot asymmetry was not observed and the meta-analysis results were not substantially influenced by any single study since the pooled mortality rate ranged from 8.9% to 11.1% following iterative removal of one study at a time. Substantial heterogeneity in the mortality rate was identified among studies (I (2) = 87%; P < .001). In a metaregression that included demographics, patient risk factors, and presenting symptoms, only a higher prevalence of diabetes mellitus was associated with a higher mortality rate (P = .03). CONCLUSIONS: In a meta-analysis of hospitalized patients in China with a diagnosis of Covid-19, the mortality rate was 9.9% and a higher diabetes mellitus prevalence was independently associated with a worse prognosis. The independent influence of diabetes mellitus with Covid-19 mortality should be viewed as hypothesis-generating and warrants further study. url: https://doi.org/10.1097/md.0000000000022439 doi: 10.1097/md.0000000000022439 id: cord-282660-9x937eus author: Muñoz Vives, Josep Maria title: Mortality Rates of Patients with Proximal Femoral Fracture in a Worldwide Pandemic: Preliminary Results of the Spanish HIP-COVID Observational Study date: 2020-05-06 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: The outbreak of coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), in December 2019 in Wuhan, People’s Republic of China, has developed into an unprecedented pandemic with enormous pressure on health-care providers around the world. A higher mortality rate has been described in older infected individuals. Patients with hip fracture are a particularly vulnerable population during this pandemic because older age is associated with a higher mortality rate. Our aim was to describe the early mortality rate and demographic variables in a hip fracture sample population in Spain during the coronavirus pandemic. METHODS: This is a multicenter, observational, retrospective, descriptive study. We collected data from 13 major hospitals in Spain from the beginning of the national state of alarm (declared on March 14, 2020, by the Spanish government) until the end of our study period on April 4, 2020. All patients who were ≥65 years of age, presented to the Emergency Department of the participating hospitals during this period with a diagnosis of proximal femoral fracture, and had a minimum follow-up of 10 days were included in the cohort. In addition to mortality, demographic and other potential prognostic variables were also collected. RESULTS: In this study, 136 patients with a hip fracture were included. Of these patients, 124 underwent a surgical procedure and 12 were managed nonoperatively. The total mortality rate was 9.6%. Sixty-two patients were tested for COVID-19, with 23 patients being positive. The mortality rate for these 23 patients was 30.4% (7 of 23 patients) at a mean follow-up of 14 days. The mortality rate was 10.3% (4 of 39) for patients who had been tested and had a negative result and 2.7% (2 of 74) for patients who had not been tested. Of the 12 patients who were managed nonoperatively, 8 (67%) died, whereas, of the 124 patients who were surgically treated, 5 (4%) died. Results differed among centers. CONCLUSIONS: There is a higher mortality rate in patients with a hip fracture and an associated positive test for COVID-19. LEVEL OF EVIDENCE: Prognostic Level IV. See Instructions for Authors for a complete description of levels of evidence. url: https://www.ncbi.nlm.nih.gov/pubmed/32618917/ doi: 10.2106/jbjs.20.00686 id: cord-314152-wd153s1g author: Noor, Farha Musharrat title: Prevalence and Associated Risk Factors of Mortality Among COVID-19 Patients: A Meta-Analysis date: 2020-09-12 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: OBJECTIVES: The main aim of this study was to find the prevalence of mortality among hospitalized COVID-19 infected patients and associated risk factors for death. METHODS: Three electronic databases including PubMed, Science Direct and Google Scholar were searched to identify relevant cohort studies of COVID-19 disease from January 1, 2020, to August 11, 2020. A random-effects model was used to calculate pooled prevalence rate (PR), risk ratio (RR) and 95% confidence interval (CI) for both effect measures. Cochrane chi-square test statistic Q, [Formula: see text] , and [Formula: see text] tests were used to measure the presence of heterogeneity. Publication bias and sensitivity of the included studies were also tested. RESULTS: In this meta-analysis, a total of 58 studies with 122,191 patients were analyzed. The pooled prevalence rate of mortality among the hospitalized COVID-19 patients was 18.88%, 95% CI (16.46–21.30), p < 0.001. Highest mortality was found in Europe [PR 26.85%, 95% CI (19.41–34.29), p < 0.001] followed by North America [PR 21.47%, 95% CI (16.27–26.68), p < 0.001] and Asia [PR 14.83%, 95% CI (12.46- 17.21), p < 0.001]. An significant association were found between mortality among COVID-19 infected patients and older age (> 65 years vs. < 65 years) [RR 3.59, 95% CI (1.87–6.90), p < 0.001], gender (male vs. female) [RR 1.63, 95% CI (1.43–1.87), p < 0.001], ICU admitted patients [RR 3.72, 95% CI (2.70–5.13), p < 0.001], obesity [RR 2.18, 95% CI (1.10–4.34), p < 0.05], hypertension [RR 2.08,95% CI (1.79–2.43) p < 0.001], diabetes [RR 1.87, 95% CI (1.23–2.84), p < 0.001], cardiovascular disease [RR 2.51, 95% CI (1.20–5.26), p < 0.05], and cancer [RR 2.31, 95% CI (1.80–2.97), p < 0.001]. In addition, significant association for high risk of mortality were also found for cerebrovascular disease, COPD, coronary heart disease, chronic renal disease, chronic liver disease, chronic lung disease and chronic kidney disease. CONCLUSION: This meta-analysis revealed that the mortality rate among COVID-19 patients was highest in the European region and older age, gender, ICU patients, patients with comorbidity had a high risk for case fatality. Those findings would help the health care providers to reduce the mortality rate and combat this pandemic to save lives using limited resources. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s10900-020-00920-x) contains supplementary material, which is available to authorized users. url: https://doi.org/10.1007/s10900-020-00920-x doi: 10.1007/s10900-020-00920-x id: cord-337692-b89ow1mf author: Petti, S. title: Ecologic association between influenza and COVID-19 mortality rates in European countries date: 2020-09-11 words: 5103.0 sentences: 251.0 pages: flesch: 41.0 cache: ./cache/cord-337692-b89ow1mf.txt txt: ./txt/cord-337692-b89ow1mf.txt summary: Ecologic studies investigating COVID-19 mortality determinants, used to make predictions and design public health control measures, generally focused on population-based variable counterparts of individual-based risk factors. We considered the 3-year average influenza (2014–2016) and COVID-19 (31 May 2020) crude mortality rates in 34 countries using EUROSTAT and ECDC databases and performed correlation and regression analyses. An apparently perplexing characteristic of the reported association between the two mortality rates was that while influenza virus circulation during the seasons considered in the present analysis was uncontrolled, SARS-CoV-2 circulation was probably limited by the widespread exceptional public health measures implemented in Europe [32] . This study reported an inverse association between number of hospital beds and mortality rates (Table 2) , thus showing that high influenza and COVID-19 mortality was also due to inefficiencies of the healthcare systems, and corroborated by data from several European countries [45] . abstract: Ecologic studies investigating COVID-19 mortality determinants, used to make predictions and design public health control measures, generally focused on population-based variable counterparts of individual-based risk factors. Influenza is not causally associated with COVID-19, but shares population-based determinants, such as similar incidence/mortality trends, transmission patterns, efficacy of non-pharmaceutical interventions, comorbidities and underdiagnosis. We investigated the ecologic association between influenza mortality rates and COVID-19 mortality rates in the European context. We considered the 3-year average influenza (2014–2016) and COVID-19 (31 May 2020) crude mortality rates in 34 countries using EUROSTAT and ECDC databases and performed correlation and regression analyses. The two variables – log transformed, showed significant Spearman's correlation ρ = 0.439 (P = 0.01), and regression coefficients, b = 0.743 (95% confidence interval, 0.272–1.214; R(2) = 0.244; P = 0.003), b = 0.472 (95% confidence interval, 0.067–0.878; R(2) = 0.549; P = 0.02), unadjusted and adjusted for confounders (population size and cardiovascular disease mortality), respectively. Common significant determinants of both COVID-19 and influenza mortality rates were life expectancy, influenza vaccination in the elderly (direct associations), number of hospital beds per population unit and crude cardiovascular disease mortality rate (inverse associations). This analysis suggests that influenza mortality rates were independently associated with COVID-19 mortality rates in Europe, with implications for public health preparedness, and implies preliminary undetected SARS-CoV-2 spread in Europe. url: https://www.ncbi.nlm.nih.gov/pubmed/32912363/ doi: 10.1017/s0950268820002125 id: cord-306205-l42w2jyk author: Ransome, Yusuf title: Is investing in religious institutions a viable pathway to reduce mortality in the population? date: 2020-06-08 words: 2980.0 sentences: 156.0 pages: flesch: 35.0 cache: ./cache/cord-306205-l42w2jyk.txt txt: ./txt/cord-306205-l42w2jyk.txt summary: The religious ecology or characteristics of religion within an area or geographic level (e.g., county, ZIP-code, country), has been linked with overall and cause-specific mortality, but directions of findings are mixed. The study found some support of an indirect association from county-level religious denominational composition, through investments in health spending, on Black and White all-cause mortality rates. Ecological studies have showed that religious ecology or characteristics of religion in area or geographic level (e.g., county, ZIP-code, country), is associated with overall and cause-specific mortality such as suicide rates (Stack 1980 , Dwyer, Clarke et al. The study found some support for an indirect association from county-level religious denominational composition to Black and White all-cause mortality rates, through investments in total institutional spending. The study (SSM-D-19-03928R2) investigated the mediating role of investments/spending in local health shaping institutions as a link between the religious ecology and all-cause mortality. abstract: There is established and consistent findings from epidemiologic studies, among individuals, that religion— broadly assessed through frequency of attending worship services—is associated with lower all-cause and cause-specific mortality attributed to suicide, alcohol, cardiovascular disease and cancer. Religious norms, social support, character, virtue, compassion, love, generosity, and religious community are among some mechanisms purported to explain lower mortality, on aggregate. The religious ecology or characteristics of religion within an area or geographic level (e.g., county, ZIP-code, country), has been linked with overall and cause-specific mortality, but directions of findings are mixed. Mechanisms to explain the links between the religious ecology and mortality included social integration, civic engagement, and social control. The manuscript (SSM-D-19-03928R2) adds a fresh and timely perspective by investigating another mechanism: investment in local healthcare spending. The study found some support of an indirect association from county-level religious denominational composition, through investments in health spending, on Black and White all-cause mortality rates. Should society or government invest finances in religious institutions to indirectly improve population health? This work adds evidence to debate that question. Future work on the topic will need to address several conceptual and methodological challenges. Conceptually, is investigating the market share of religious denominations (i.e., % Catholics vs % Protestants) relevant today given diversity in population and declining trends of worship attendance? Is mortality the most relevant for moving policy or should the focus be on well-being? Methodologically, are there alternate observable measures religious investments/spending in the local economy? Mechanisms, challenges, and opportunities for social epidemiology research on this topic are discussed. url: https://www.sciencedirect.com/science/article/pii/S0277953620303257?v=s5 doi: 10.1016/j.socscimed.2020.113106 id: cord-351163-lyj94xn8 author: Rocha-Singh, Krishna J. title: Retrospective Real-World Studies of Paclitaxel and Mortality: Defining the Many Faces of Bias date: 2020-05-14 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: [Figure: see text] url: https://www.ncbi.nlm.nih.gov/pubmed/32412550/ doi: 10.1016/j.jcin.2020.05.006 id: cord-298201-z68j0c63 author: Schlüter, Benjamin-Samuel title: Long-term trends in seasonality of mortality in urban Madagascar: the role of the epidemiological transition date: 2020-02-06 words: 6359.0 sentences: 307.0 pages: flesch: 54.0 cache: ./cache/cord-298201-z68j0c63.txt txt: ./txt/cord-298201-z68j0c63.txt summary: Objective: Based on death notification data from Antananarivo, the capital city of Madagascar, this study assesses seasonal patterns of all-cause and cause-specific mortality by age groups and evaluates how these patterns changed over the period 1976–2015. In adults aged 60 and above, all-cause mortality rates are the highest in the dry and cold season, due to peaks in cardiovascular diseases, with little change over time. Considering children aged 1 to 5, seasonality of mortality associated with these two broad causes of death (the group of diarrhea, lower respiratory, and other common infectious diseases, and the group of nutritional deficiencies) also exhibit this pattern but with a larger amplitude. In infants, the seasonality of deaths is dominated by the association between hot temperatures and rainfall, and two groups of causes: (1) diarrhea, lower respiratory, and other common infectious diseases, and (2) nutritional deficiencies. abstract: Background: Seasonal patterns of mortality have been identified in Sub-Saharan Africa but their changes over time are not well documented. Objective: Based on death notification data from Antananarivo, the capital city of Madagascar, this study assesses seasonal patterns of all-cause and cause-specific mortality by age groups and evaluates how these patterns changed over the period 1976–2015. Methods: Monthly numbers of deaths by cause were obtained from death registers maintained by the Municipal Hygiene Office in charge of verifying deaths before the issuance of burial permits. Generalized Additive Mixed regression models (GAMM) were used to test for seasonality in mortality and its changes over the last four decades, controlling for long-term trends in mortality. Results: Among children, risks of dying were the highest during the hot and rainy season, but seasonality in child mortality has significantly declined since the mid-1970s, as a result of declines in the burden of infectious diseases and nutritional deficiencies. In adults aged 60 and above, all-cause mortality rates are the highest in the dry and cold season, due to peaks in cardiovascular diseases, with little change over time. Overall, changes in the seasonality of all-cause mortality have been driven by shifts in the hierarchy of causes of death, while changes in the seasonality within broad categories of causes of death have been modest. Conclusion: Shifts in disease patterns brought about by the epidemiological transition, rather than changes in seasonal variation in cause-specific mortality, are the main drivers of trends in the seasonality of all-cause mortality. url: https://doi.org/10.1080/16549716.2020.1717411 doi: 10.1080/16549716.2020.1717411 id: cord-014464-m5n250r2 author: Sole-Violan, J title: Lethal influenza virus A H1N1 infection in two relatives with autosomal dominant GATA-2 deficiency date: 2013-03-19 words: 98961.0 sentences: 5553.0 pages: flesch: 54.0 cache: ./cache/cord-014464-m5n250r2.txt txt: ./txt/cord-014464-m5n250r2.txt summary: Results In preliminary analysis of categorical data, a signifi cantly (Fisher exact test) greater proportion of patients with compared with without the following fi ndings did not survive; history of alcohol use (P = 0.05); the presence of lethargy (P = 0.01), confusion (P = 0.03), nausea (P = 0.04), abdominal pain (P = 0.02), or the need for vasopressors (P = 0.002), oxygen, mechanical ventilation, or steroids (all P = 0.004) at presentation; and excessive bleeding at surgery (P = 0.01). Methods To prospectively re-evaluate the normal range and to analyze the potential impact of biometric data on ICG-PDR, we measured ICG-PDR (i.v. injection of 0.25 mg/kg ICG; LiMON, Pulsion, Munich, Introduction Mixed venous oxygen saturation (SVO 2 ) represents a well-recognized parameter of oxygen delivery (DO 2 )-consumption (VO 2 ) mismatch and its use has been advocated in critically ill patients in order to guide hemodynamic resuscitation [1] and oxygen delivery optimization. abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642469/ doi: 10.1186/cc11953 id: cord-003571-upogtny6 author: Viboud, Cécile title: The 1918 Influenza Pandemic: Looking Back, Looking Forward date: 2018-10-20 words: 3831.0 sentences: 155.0 pages: flesch: 41.0 cache: ./cache/cord-003571-upogtny6.txt txt: ./txt/cord-003571-upogtny6.txt summary: In the present commentary, we place these 12 articles in the context of a growing body of work on the archeo-epidemiology of past pandemics, the socioeconomic and geographic drivers of influenza mortality and natality impact, and renewed interest in immune imprinting mechanisms and the development of novel influenza vaccines. In the present commentary, we place these 12 articles in the context of a growing body of work on the archeo-epidemiology of past pandemics, the socioeconomic and geographic drivers of influenza mortality and natality impact, and renewed interest in immune imprinting mechanisms and the development of novel influenza vaccines. age patterns; history of epidemiology; influenza; mortality; pandemic; prior immunity One hundred years after the fact, the 1918 influenza pandemic remains one of the most important epidemics of the modern medical era; it was significant for its impact on both human health and the development of epidemiology and other medical sciences. abstract: In commemoration of the centennial of the 1918 influenza pandemic, the American Journal of Epidemiology has convened a collection of 12 articles that further illuminate the epidemiology of that pandemic and consider whether we would be more prepared if an equally deadly influenza virus were to emerge again. In the present commentary, we place these 12 articles in the context of a growing body of work on the archeo-epidemiology of past pandemics, the socioeconomic and geographic drivers of influenza mortality and natality impact, and renewed interest in immune imprinting mechanisms and the development of novel influenza vaccines. We also highlight persisting mysteries in the origins and severity of the 1918 pandemic and the need to preserve rapidly decaying information that may provide treasure troves for future generations. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454441/ doi: 10.1093/aje/kwy207 id: cord-000522-d498qj2b author: Vincent, Jean-Louis title: Reducing mortality in sepsis: new directions date: 2002-12-05 words: 8709.0 sentences: 431.0 pages: flesch: 48.0 cache: ./cache/cord-000522-d498qj2b.txt txt: ./txt/cord-000522-d498qj2b.txt summary: Five topics were selected that have been shown in randomized, controlled trials to reduce mortality: limiting the tidal volume in acute lung injury or acute respiratory distress syndrome, early goal-directed therapy, use of drotrecogin alfa (activated), use of moderate doses of steroids, and tight control of blood sugar. The present article provides guidelines from experts in the field on optimal patient selection and timing for each intervention, and provides advice on how to integrate new therapies into ICU practice, including protocol development, so that mortality rates from this disease process can be reduced. The interventions discussed encompassed low tidal volume in patients with acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) (Edward Abraham), early goal-directed therapy (EGDT) (Emanuel Rivers), drotrecogin alfa (activated) (Gordon Bernard), moderate-dose corticosteroids (Djillali Annane), and tight control of blood sugar (Greet Van den Berghe). abstract: Considerable progress has been made in the past few years in the development of therapeutic interventions that can reduce mortality in sepsis. However, encouraging physicians to put the results of new studies into practice is not always simple. A roundtable was thus convened to provide guidance for clinicians on the integration and implementation of new interventions into the intensive care unit (ICU). Five topics were selected that have been shown in randomized, controlled trials to reduce mortality: limiting the tidal volume in acute lung injury or acute respiratory distress syndrome, early goal-directed therapy, use of drotrecogin alfa (activated), use of moderate doses of steroids, and tight control of blood sugar. One of the principal investigators for each study was invited to participate in the roundtable. The discussions and questions that followed the presentation of data by each panel member enabled a consensus recommendation to be derived regarding when each intervention should be used. Each new intervention has a place in the management of patients with sepsis. Furthermore, and importantly, the therapies are not mutually exclusive; many patients will need a combination of several approaches – an 'ICU package'. The present article provides guidelines from experts in the field on optimal patient selection and timing for each intervention, and provides advice on how to integrate new therapies into ICU practice, including protocol development, so that mortality rates from this disease process can be reduced. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239386/ doi: 10.1186/cc1860 id: cord-269777-dm6te7nw author: Vukina, T title: Intervention decision model to prevent spiking mortality of turkeys date: 1998-07-01 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: Abstract Based on the daily records on turkeys' mortalities for the series of flocks placed on different farms in a relatively compact geographical area for the period of approximately 2 yr and other relevant explanatory variables, the goal of the research was to design a decision model to determine whether or not to use the fluorquinolone antibiotic, sarafloxacin, to prevent spiking mortality of turkeys. The core of the designed decision model is the forecasting model that attempts to ex-ante predict the cumulative flock mortality for the period between 8 and 28 d of age. Forecasts were generated with the parameters of the linear regression model where continuous values of daily mortalities served as a dependent variable. The decision variable is a binary (yes/no) choice variable, where “yes” means “go ahead with treatment” and “no” means “do nothing”. If the predicted cumulative mortality for the period between 8 and 28 d of age exceeds 9% of the total initial placement, the model generates a “yes” signal. If the predicted cumulative mortality for the same period is below 9% of the total initial placement, the model generates a “no” signal. The results indicate a reasonable accuracy of the prediction model where the number of correct prediction increases and the number of incorrect predictions falls very fast as the forecasting window shortens. The intervention decision model could help veterinarians in making decisions on whether or not to treat the suspect flocks. url: https://www.sciencedirect.com/science/article/pii/S0032579119409061 doi: 10.1093/ps/77.7.950 id: cord-294350-6veeygzp author: Yu, Caizheng title: Clinical Characteristics, Associated Factors, and Predicting COVID-19 Mortality Risk: A Retrospective Study in Wuhan, China date: 2020-05-27 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: Introduction Coronavirus disease 2019 (COVID-19) has become a serious global pandemic. This study investigates the clinical characteristics and risk factors for COVID-19 mortality, and establishes a novel scoring system to predict mortality risk in COVID-19 patients. Methods A cohort of 1,663 hospitalized COVID-19 patients in Wuhan, China, of whom 212 died and 1,252 recovered, were included in the present study. Demographic, clinical, and laboratory data on admission were collected from electronic medical records between January 14, 2020, and February 28, 2020. Clinical outcomes were collected until March 26, 2020. Multivariable logistic regression was used to explore the association between potential risk factors and COVID-19 mortality. The receiver operating characteristic curve was used to predict COVID-19 mortality risk. All analyses were conducted in April 2020. Results Multivariable regression showed increased odds of COVID-19 mortality associated with older age (OR=2.15, 95% CI=1.35, 3.43), male sex (OR=1.97, 95% CI=1.29, 2.99), history of diabetes (OR=2.34, 95% CI=1.45, 3.76), lymphopenia (OR=1.59, 95% CI=1.03, 2.46), and increased procalcitonin (OR=3.91, 95% CI=2.22, 6.91, per SD increase) on admission. Spline regression analysis indicated that the correlation between procalcitonin levels and COVID-19 mortality was nonlinear (p=0.0004 for nonlinearity). The area under the receiver operating curve of the COVID-19 mortality risk was 0.765 (95% CI=0.725, 0.805). Conclusions The independent risk factors for COVID-19 mortality included older age, male sex, history of diabetes, lymphopenia, and increased procalcitonin, which could help clinicians to identify COVID-19 patients with poor prognosis at an earlier stage. The COVID-19 mortality risk score model may assist clinicians in reducing COVID-19-related mortality by implementing better strategies for more effective use of limited medical resources. url: https://api.elsevier.com/content/article/pii/S074937972030218X doi: 10.1016/j.amepre.2020.05.002 id: cord-003011-vclnb0eh author: de Almeida, Carlos Podalirio Borges title: Predictors of In-Hospital Mortality among Patients with Pulmonary Tuberculosis: A Systematic Review and Meta-analysis date: 2018-05-08 words: 2833.0 sentences: 173.0 pages: flesch: 45.0 cache: ./cache/cord-003011-vclnb0eh.txt txt: ./txt/cord-003011-vclnb0eh.txt summary: title: Predictors of In-Hospital Mortality among Patients with Pulmonary Tuberculosis: A Systematic Review and Meta-analysis The aim of this systematic review and meta-analysis is to identify predictors of in-hospital mortality among patients with PTB. Methods: We searched MEDLINE, EMBASE, and Global Health, for cohort and case-control studies that reported risk factors for in-hospital mortality in PTB. We therefore conducted a systematic review and meta-analysis to establish predictors of in-hospital mortality among patients with pulmonary TB. Eligible trials met the following criteria 1 : cohort or case-control design 2 ; explored risk factors for in-hospital mortality among patients with pulmonary TB in an adjusted analysis. This systematic review and meta-analysis is expected to serve as a basis for evidence to reduce in-hospital mortality in TB patients, and as a guide for future research based on identified knowledge gaps. Predictors of in-hospital mortality among patients with pulmonary tuberculosis: a protocol of systematic review and meta-analysis of observational studies abstract: Background: There is uncertainty regarding which factors are associated with in-hospital mortality among patients with pulmonary TB (PTB). The aim of this systematic review and meta-analysis is to identify predictors of in-hospital mortality among patients with PTB. Methods: We searched MEDLINE, EMBASE, and Global Health, for cohort and case-control studies that reported risk factors for in-hospital mortality in PTB. We pooled all factors that were assessed for an association, and presented relative associations as pooled odds ratios (ORs). Results: We identified 2,969 records, of which we retrieved 51 in full text; 11 cohort studies that evaluated 5,468 patients proved eligible. Moderate quality evidence suggested an association with co-morbid malignancy and in-hospital mortality (OR 1.85; 95% CI 1.01–3.40). Low quality evidence showed no association with positive sputum smear (OR 0.99; 95% CI 0.40–2.48), or male sex (OR 1.09, 95% CI 0.84–1.41), and very low quality evidence showed no association with diabetes mellitus (OR 1.31, 95% IC 0.38–4.46), and previous TB infection (OR 2.66, 95% CI 0.48–14.87). Conclusion: Co-morbid malignancy was associated with increased risk of in-hospital death among pulmonary TB patients. There is insufficient evidence to confirm positive sputum smear, male sex, diabetes mellitus, and previous TB infection as predictors of in-hospital mortality in TB patients. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940698/ doi: 10.1038/s41598-018-25409-5 id: cord-003532-lcgeingz author: nan title: 39th International Symposium on Intensive Care and Emergency Medicine: Brussels, Belgium, 19-22 March 2019 date: 2019-03-19 words: 79997.0 sentences: 5146.0 pages: flesch: 52.0 cache: ./cache/cord-003532-lcgeingz.txt txt: ./txt/cord-003532-lcgeingz.txt summary: It''s proposed to evaluate the association between myocardial injury biomarkers, high-sensitive troponin T (hs-cTnT) and N-terminal pro-brain natriuretic peptide (NT-ProBNP), with inflammatory mediators (IL-6, IL-1Β , IL-8, IL-10, IL-12 / IL-23p40, IL17A, IL-21 and TNF-α ) and biomarkers, C protein reactive (CPR) and procalcitonin (PCT), in septic patients Methods: This was a prospective cohort study performed in three intensive care units, from September 2007 to September 2010 enrolling patients with sepsis (infection associated with organ dysfunction), and septic shock (hypotension refractory by fluids infusion requiring vasopressor). Blood samples were collected up to 48h after the development of first organ dysfunction (D0) and on the 7th day after inclusion in the study (D7) Results: Ninety-five patients were enrolled, with median age 64 years (interquatile?48-78), APACHE II: median 19 (14-22), SOFA: median 8 (5-10); 24.2% were admitted in ICU with sepsis and 75.8% with septic shock. abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423782/ doi: 10.1186/s13054-019-2358-0 id: cord-005497-w81ysjf9 author: nan title: 40th International Symposium on Intensive Care & Emergency Medicine: Brussels, Belgium. 24-27 March 2020 date: 2020-03-24 words: 103623.0 sentences: 6176.0 pages: flesch: 53.0 cache: ./cache/cord-005497-w81ysjf9.txt txt: ./txt/cord-005497-w81ysjf9.txt summary: The positive NC group had more plasma transfusion (p-value 0.03) and a lower median hematocrit at 24 hrs (p-value 0.013), but similar hospital length of stay (p=0.17) and mortality rate (p=0.80) Conclusions: NC at ICU admission identifies subclinical AKI in TBI patients and it maight be used to predictclinical AKI. In patients with pneumonia requiring intensive care (ICU) admission, we hypothesise that abnormal right ventricular (RV) function is associated with an increased 90-day mortality. The objective of this study was to describe the incidence of each AKI stages as defined by KDIGO definition (with evaluation of urine output, serum creatinine and initiation of renal replacement therapy (RRT)), in a mixed medical and surgical population of patients hospitalized in ICU and PCU over a 10-year period (2008-2018). This study aimed at investigating the relationship of goal-directed energy and protein adequacy on clinical outcomes which includes mortality, intensive care unit(ICU) and hospital length of stay (LOS), and length of mechanical ventilation (LOMV). abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092506/ doi: 10.1186/s13054-020-2772-3 id: cord-005777-6rvfsx4p author: nan title: PS 0420-0716 date: 2007-08-25 words: 59217.0 sentences: 3634.0 pages: flesch: 53.0 cache: ./cache/cord-005777-6rvfsx4p.txt txt: ./txt/cord-005777-6rvfsx4p.txt summary: We prospectively recorded data of all patients who were newly diagnosed with AF and all those with a septic shock on a surgical ICU (no cardiac surgery) during a one year period according to the requirements of the local ethical committee. Our aim was to evaluate the predictive role of admission APACHE II, admission and total maximum SOFA score, hypoalbuminemia, increased serum creatinine, C-reactive protein, lactate, and serum blood glucose for the 30-day mortality of septic patients admitted to medical ICU. The aim of this study was to analyze the clinical presentation and to evaluate mortality associated factors (timing and accurancy of diagnosis, timing of surgery, severity score and organ failure, surgical and medical treatments). Data were extracted independently to assess intention to treat intensive care unit (ICU) and hospital mortality, days of mechanical ventilation, length of stay, incidence of ventilator-associated pneumonia and pneumothorax, and associated complications of the implemented intervention. abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095424/ doi: 10.1007/s00134-007-0823-8 id: cord-005814-ak5pq312 author: nan title: 8th European Congress of Intensive Care Medicine Athens - Greece, October 18–22, 1995 Abstracts date: 1995 words: 179164.0 sentences: 12028.0 pages: flesch: 56.0 cache: ./cache/cord-005814-ak5pq312.txt txt: ./txt/cord-005814-ak5pq312.txt summary: Results: In 5 patients with treated SS, 16 tests were performed (VL n=8; Dobu n=4; NA n=4 Method: Septic shock was defined as severe sepsis with either persistent hypotension (mean arterial pressure; MAP<70 mmHg) or the requirement for a noradrenaline (NA) infusion ~> 0.1 ~g/kg/min with a MAP _< 90mmHg. Cardiovascular support was limited to NA + dobutamine (DB), 546C88 was administered for up to 8 h at a fixed dose-rate of either i, 2.5, 5, 10 or 20 mg/kg/h iv. Methods: Fourteen cases were s~udied,their gestational age ranged from(27-32)ws.Continnous positive air way pressure was applied to six cases at Peep level from (3-6)cm H2o through nasal pronge,(group I),the other 8 cases were managed as routine,(group II).Blood gases, TcPO2,TcCo2,resp.rate,depth and pattern were monitored for assessment of tissue Oxygenation and ventilation, Results: Our rasults showed that early application of CPAP improve ventilation among (83.3%)of cases,while (16.7%)of cases need IMV.The cases of group II need IMV among (75%)of the studied cases during the second or the third day of life. abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095534/ doi: 10.1007/bf02426401 id: cord-005816-i54q5gsu author: nan title: 10(th) European Congress of Trauma and Emergency Surgery: May 13–17, 2009 Antalya, Turkey date: 2009-08-06 words: 83124.0 sentences: 5617.0 pages: flesch: 53.0 cache: ./cache/cord-005816-i54q5gsu.txt txt: ./txt/cord-005816-i54q5gsu.txt summary: Several factors such as the initial lack of symptoms, a low diagnostic sensitivity of the CT (34% false negatives), and the nonoperative management of solid organ injuries, have contributed to a delayed diagnosis in one of every five patients in our series, but this has not led to a significant increase in septic complications in this group. Method: The demographic features, the treatments, the intensity of the illness and mortality rate of the 155 patients in Afyon Kocatepe University General Surgery clinic between the years 2006 Background: Enterocutaneous fistula continues to be a serious surgical problem. Introduction: In our previous study, we examined the treatment results of burn patients older than 45 years, and found a significant increase in mortality with increasing age groups. Methods: Data on emergency surgical cases and admissions to the surgical service over a 3-month period were collected and analyzed; this included patient demographics, referral sources, diagnosis, operation, and length of stay (LOS Conclusion: Emergency workload represents a significant part of the work for the general surgeons. abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095784/ doi: 10.1007/s00068-009-8001-z id: cord-010980-sizuef1v author: nan title: ECTES Abstracts 2020 date: 2020-05-11 words: 132644.0 sentences: 8727.0 pages: flesch: 53.0 cache: ./cache/cord-010980-sizuef1v.txt txt: ./txt/cord-010980-sizuef1v.txt summary: We hypothesized that presentation to a PTC would yield increased mortality when subspecialty intervention was required and that this would be most pronounced at night when in-house attending coverage is absent at all state PTCs. Materials and methods: A review of the Pennsylvania Trauma Outcome Study (PTOS) database was performed to capture patients aged 12-18 who underwent any non-orthopedic trauma surgery. Traumatic subaxial cervical fractures: functional prognostic factors and survival analysis Introduction: The main goal of this study is to identify the risk factors for poor functional outcomes and to analyze the overall survival (OS) and complications rate in patients with traumatic cervical spinal cord injury (SCI) and subaxial cervical fracture (SACF) treated with open surgical fixation. After applying a multiple imputation on all the study variables, a logistic regression generalized estimating equation after adjustment for age, sex, mechanism of trauma, and the injury severity score as covariates and hospitals as a cluster assessed an association between quartile of patient volume in intensive care unit and hospital mortality. abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7223217/ doi: 10.1007/s00068-020-01343-y id: cord-014996-p6q0f37c author: nan title: Posters_Monday_12 October 2009 date: 2009-08-06 words: 85190.0 sentences: 5288.0 pages: flesch: 54.0 cache: ./cache/cord-014996-p6q0f37c.txt txt: ./txt/cord-014996-p6q0f37c.txt summary: Data recorded on admission were the patient demographics with, acute physiology and chronic health evaluation II score (APACHE II), and type of admission; during intensive care stay, sepsis-related organ failure assessment score (SOFA) and clinical concomitant factors and conditions. For each severe septic patient the following data was registered: time delay, APACHE II and SOFA scores at ICU admission, diagnosis, the rate of compliance with the resucitation and management bundles, microbiological data, evolution of levels of serum lactate, empiric antibiotic therapy, length of stay and mortality in ICU. Sepsis and septic shock remain the most important causes of acute kidney injury (AKI) in critically ill patients and account for more than 50% of cases of acute renal failure (ARF) in intensive care units (ICU). There were no significant differences between the demographic data (sex, age) or the data on admission to intensive care (APACHE II score, ratio of medical to surgical patients) and duration of mechanical ventilation between the two groups. abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094934/ doi: 10.1007/s00134-009-1593-2 id: cord-015082-l629n8is author: nan title: Poster Sessions 323-461 date: 2002-08-29 words: 26569.0 sentences: 1648.0 pages: flesch: 52.0 cache: ./cache/cord-015082-l629n8is.txt txt: ./txt/cord-015082-l629n8is.txt summary: 14 patients awaiting urgent cardiac surgical re-vascularisation were studied with measurement of: spirometry; percentage increase in transfer factor from sitting to lying position (TF) as an indicator of micro-vascular lung disease; overnight oximetry on air; and 24hour holter monitoring Patients, who were reintubated on decreased indices of arterial oxygenation under MOSF progressing died in 100% cases ( NIMV is effective method in complex therapy of ARF, developing in postoperative period after cardiac surgery, that leads to significant improvement of lungs biomechanics and gases change function. In a prospective observational study we performed bedside ptO2 measurements in 8 patients with sepsis/septic shock to gain insight in ptO2 values and their dynamic changes related to the course of the illness, as well as investigating the practical applicability of tissue oxygen measurement in the ICU setting. abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095316/ doi: 10.1007/s00134-002-1455-7 id: cord-015126-cyhcbk1j author: nan title: PS 0036-0344 date: 2007-08-25 words: 59175.0 sentences: 3672.0 pages: flesch: 54.0 cache: ./cache/cord-015126-cyhcbk1j.txt txt: ./txt/cord-015126-cyhcbk1j.txt summary: We compared them with ≥70 years old and an ICU stay < 30 days patients, the differences in ICU mortality, Apache II, age, gender and the necessity for renal replacement therapy (RRT) were not significant (see table) . The patients with mild form of acute pancreatitis had low mortality rate (similar to general ward population) despite positive ICU admission criteria in our case series with fifty per cent development of severe form with organ dysfunction/failure later on. Collected data:Demographics,Management prior and during ICU hospitalization (sedation, catecolamin drug use, blood product transfusion, intra-cranial pressure monitoring, neurosurgical emergency surgery etc.),CT-Scan results, Daily worst Glasgow coma scale, admission Simplified Acute Physiology Score II. This prospective interventional study performed in a surgical Intensive Care Unit of a tertiary University Hospital included 35 (21 males) mechanically ventilated and sedated patients with acute cardiovascular failure requiring cardiac output measurement (transpulmonary thermodilution technique)and a fluid challenge. abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095535/ doi: 10.1007/s00134-007-0820-y id: cord-335975-m6lkrehi author: nan title: Proceedings of Réanimation 2018, the French Intensive Care Society International Congress date: 2018-02-05 words: 89374.0 sentences: 5327.0 pages: flesch: 52.0 cache: ./cache/cord-335975-m6lkrehi.txt txt: ./txt/cord-335975-m6lkrehi.txt summary: A qSOFA score relying on 3 simple clinical criteria (respiratory rate, mental status and systolic blood pressure) has been proposed to better identify septic patients with associated higher mortality outside the intensive care unit (Seymour CW et al., JAMA 2016) . We propose to determine whether the arterial oxygen pressure (PaO2) at intensive care unit (ICU) admission affects mortality at day 28 (D28) in patients with septic shock subjected to mechanical out-of-hospital ventilation. Conclusion: In this study, we report a significant association between hyperoxemia at ICU admission and mortality at D28 in patients with septic shock subjected to pre-hospital invasive mechanical ventilation. The aim of this study was to describe outcome of pediatric patient with hematologic disease hospitalized in our intensive care unit for respiratory failure and to investigate the clinical variables associated with mortality. abstract: nan url: https://doi.org/10.1186/s13613-017-0345-7 doi: 10.1186/s13613-017-0345-7 id: cord-341063-3rqnu5bu author: nan title: 38th International Symposium on Intensive Care and Emergency Medicine: Brussels, Belgium. 20-23 March 2018 date: 2018-03-29 words: 98602.0 sentences: 6494.0 pages: flesch: 52.0 cache: ./cache/cord-341063-3rqnu5bu.txt txt: ./txt/cord-341063-3rqnu5bu.txt summary: Procacitonin (PCT) emerges as a possible predictive tool in cardiothoracic intensive care unit (CTICU).We aim at testing the predictive power of PCT for early morbidity, prolonged ventilation, ICU and hospital stay, in patients developing early fever after cardiac surgery Methods: A retrospective descriptive study done in tertiary cardiac center, enrolling patients who stayed for more than 24 hours post-operatively in the CTICU Risk stratification included additive Euro score and PCT immunoluminometricaly prior to surgery and every 48 hours in response to onset of fever. Prognostic accuracy of quick sequential organ failure assessment (qSOFA) score for mortality: systematic review and meta-analysis Introduction: The purpose of this study was to summarize the evidence assessing the qSOFA [1] , calculated in admission of the patient in emergency department (ED) or intensive care unit (ICU), as a predictor of mortality. abstract: nan url: https://doi.org/10.1186/s13054-018-1973-5 doi: 10.1186/s13054-018-1973-5 id: cord-355038-o2hr5mox author: nan title: Proceedings of Réanimation 2020, the French Intensive Care Society International Congress date: 2020-02-11 words: 102485.0 sentences: 7028.0 pages: flesch: 52.0 cache: ./cache/cord-355038-o2hr5mox.txt txt: ./txt/cord-355038-o2hr5mox.txt summary: Conclusion: In patients with moderate-to-severe ARDS, a higher tidal volume under PSV within the 72 h following neuromuscular blockers cessation is independently associated with the 28-day mortality.Compliance with ethics regulations: Yes. Kaplan-Meier estimate of the cumulative probability of survival according to the mean tidal volume (Vt)-lower of higher than 8 ml/ kg-under pressure support ventilation (PSV) during the "transition period" transfusion is associated with adverse events, and equipoise remains on the optimal transfusion strategy in oncologic patients in surgical setting. Compliance with ethics regulations: Yes. Patients and methods: In a retrospective monocentric study (01/2013-01/2017) conducted in cardio-vascular surgical intensive care unit (ICU) in Henri Mondor teaching hospital, all consecutive adult patients who underwent peripheral VA-ECMO were included, with exclusion of those dying in the first 24 h. Compliance with ethics regulations: Yes. Rationale: Acute respiratory failure is the leading reason for intensive care unit (ICU) admission in immunocompromised patients and the need for invasive mechanical ventilation has become a major clinical end-point in randomized controlled trials (RCT). abstract: nan url: https://www.ncbi.nlm.nih.gov/pubmed/32048060/ doi: 10.1186/s13613-020-0623-7 ==== make-pages.sh questions [ERIC WAS HERE] ==== make-pages.sh search /data-disk/reader-compute/reader-cord/bin/make-pages.sh: line 77: /data-disk/reader-compute/reader-cord/tmp/search.htm: No such file or directory Traceback (most recent call last): File "/data-disk/reader-compute/reader-cord/bin/tsv2htm-search.py", line 51, in with open( TEMPLATE, 'r' ) as handle : htm = handle.read() FileNotFoundError: [Errno 2] No such file or directory: '/data-disk/reader-compute/reader-cord/tmp/search.htm' ==== make-pages.sh topic modeling corpus Zipping study carrel