id sid tid token lemma pos cord-027201-owzhv0xy 1 1 key key NN cord-027201-owzhv0xy 1 2 : : : cord-027201-owzhv0xy 2 1 cord-027201-owzhv0xy cord-027201-owzhv0xy NNP cord-027201-owzhv0xy 2 2 authors author NNS cord-027201-owzhv0xy 2 3 : : : cord-027201-owzhv0xy 2 4 Tkacz Tkacz NNP cord-027201-owzhv0xy 2 5 , , , cord-027201-owzhv0xy 2 6 Magdalena Magdalena NNP cord-027201-owzhv0xy 2 7 A. a. NN cord-027201-owzhv0xy 2 8 ; ; : cord-027201-owzhv0xy 2 9 Chromiński Chromiński NNP cord-027201-owzhv0xy 2 10 , , , cord-027201-owzhv0xy 2 11 Kornel Kornel NNP cord-027201-owzhv0xy 2 12 title title NN cord-027201-owzhv0xy 2 13 : : : cord-027201-owzhv0xy 3 1 Advantage advantage NN cord-027201-owzhv0xy 3 2 of of IN cord-027201-owzhv0xy 3 3 Using use VBG cord-027201-owzhv0xy 3 4 Spherical Spherical NNP cord-027201-owzhv0xy 3 5 over over IN cord-027201-owzhv0xy 3 6 Cartesian Cartesian NNP cord-027201-owzhv0xy 3 7 Coordinates Coordinates NNPS cord-027201-owzhv0xy 3 8 in in IN cord-027201-owzhv0xy 3 9 the the DT cord-027201-owzhv0xy 3 10 Chromosome Chromosome NNP cord-027201-owzhv0xy 3 11 Territories Territories NNPS cord-027201-owzhv0xy 3 12 3D 3D NNP cord-027201-owzhv0xy 3 13 Modeling Modeling NNP cord-027201-owzhv0xy 3 14 date date NN cord-027201-owzhv0xy 3 15 : : : cord-027201-owzhv0xy 3 16 2020 2020 CD cord-027201-owzhv0xy 3 17 - - HYPH cord-027201-owzhv0xy 3 18 06 06 CD cord-027201-owzhv0xy 3 19 - - SYM cord-027201-owzhv0xy 3 20 15 15 CD cord-027201-owzhv0xy 3 21 journal journal NN cord-027201-owzhv0xy 3 22 : : : cord-027201-owzhv0xy 4 1 Computational Computational NNP cord-027201-owzhv0xy 4 2 Science Science NNP cord-027201-owzhv0xy 4 3 - - HYPH cord-027201-owzhv0xy 4 4 ICCS ICCS NNP cord-027201-owzhv0xy 4 5 2020 2020 CD cord-027201-owzhv0xy 5 1 DOI DOI NNP cord-027201-owzhv0xy 5 2 : : : cord-027201-owzhv0xy 5 3 10.1007/978 10.1007/978 CD cord-027201-owzhv0xy 5 4 - - HYPH cord-027201-owzhv0xy 5 5 3 3 CD cord-027201-owzhv0xy 5 6 - - HYPH cord-027201-owzhv0xy 5 7 030 030 CD cord-027201-owzhv0xy 5 8 - - HYPH cord-027201-owzhv0xy 5 9 50417 50417 CD cord-027201-owzhv0xy 5 10 - - HYPH cord-027201-owzhv0xy 5 11 5_49 5_49 CD cord-027201-owzhv0xy 5 12 sha sha NNP cord-027201-owzhv0xy 5 13 : : : cord-027201-owzhv0xy 5 14 ef49e2cfae011c9ddf73cd12ded62537f42529c5 ef49e2cfae011c9ddf73cd12ded62537f42529c5 NNP cord-027201-owzhv0xy 6 1 doc_id doc_id CD cord-027201-owzhv0xy 6 2 : : : cord-027201-owzhv0xy 6 3 27201 27201 CD cord-027201-owzhv0xy 6 4 cord_uid cord_uid NNS cord-027201-owzhv0xy 6 5 : : : cord-027201-owzhv0xy 7 1 owzhv0xy owzhv0xy FW cord-027201-owzhv0xy 7 2 This this DT cord-027201-owzhv0xy 7 3 paper paper NN cord-027201-owzhv0xy 7 4 shows show VBZ cord-027201-owzhv0xy 7 5 results result NNS cord-027201-owzhv0xy 7 6 of of IN cord-027201-owzhv0xy 7 7 chromosome chromosome NN cord-027201-owzhv0xy 7 8 territory territory NN cord-027201-owzhv0xy 7 9 modeling model VBG cord-027201-owzhv0xy 7 10 in in IN cord-027201-owzhv0xy 7 11 two two CD cord-027201-owzhv0xy 7 12 cases case NNS cord-027201-owzhv0xy 7 13 : : : cord-027201-owzhv0xy 7 14 when when WRB cord-027201-owzhv0xy 7 15 the the DT cord-027201-owzhv0xy 7 16 implementation implementation NN cord-027201-owzhv0xy 7 17 of of IN cord-027201-owzhv0xy 7 18 the the DT cord-027201-owzhv0xy 7 19 algorithm algorithm NN cord-027201-owzhv0xy 7 20 was be VBD cord-027201-owzhv0xy 7 21 based base VBN cord-027201-owzhv0xy 7 22 on on IN cord-027201-owzhv0xy 7 23 Cartesian cartesian JJ cord-027201-owzhv0xy 7 24 coordinates coordinate NNS cord-027201-owzhv0xy 7 25 and and CC cord-027201-owzhv0xy 7 26 when when WRB cord-027201-owzhv0xy 7 27 implementation implementation NN cord-027201-owzhv0xy 7 28 was be VBD cord-027201-owzhv0xy 7 29 made make VBN cord-027201-owzhv0xy 7 30 with with IN cord-027201-owzhv0xy 7 31 Spherical spherical JJ cord-027201-owzhv0xy 7 32 coordinates coordinate NNS cord-027201-owzhv0xy 7 33 . . . cord-027201-owzhv0xy 8 1 In in IN cord-027201-owzhv0xy 8 2 the the DT cord-027201-owzhv0xy 8 3 article article NN cord-027201-owzhv0xy 8 4 , , , cord-027201-owzhv0xy 8 5 the the DT cord-027201-owzhv0xy 8 6 summary summary NN cord-027201-owzhv0xy 8 7 of of IN cord-027201-owzhv0xy 8 8 measurements measurement NNS cord-027201-owzhv0xy 8 9 of of IN cord-027201-owzhv0xy 8 10 computational computational JJ cord-027201-owzhv0xy 8 11 times time NNS cord-027201-owzhv0xy 8 12 of of IN cord-027201-owzhv0xy 8 13 simulation simulation NN cord-027201-owzhv0xy 8 14 of of IN cord-027201-owzhv0xy 8 15 chromatin chromatin NN cord-027201-owzhv0xy 8 16 decondensation decondensation NN cord-027201-owzhv0xy 8 17 process process NN cord-027201-owzhv0xy 8 18 ( ( -LRB- cord-027201-owzhv0xy 8 19 which which WDT cord-027201-owzhv0xy 8 20 led lead VBD cord-027201-owzhv0xy 8 21 to to TO cord-027201-owzhv0xy 8 22 constitute constitute VB cord-027201-owzhv0xy 8 23 the the DT cord-027201-owzhv0xy 8 24 chromosome chromosome NN cord-027201-owzhv0xy 8 25 territory territory NN cord-027201-owzhv0xy 8 26 ) ) -RRB- cord-027201-owzhv0xy 8 27 was be VBD cord-027201-owzhv0xy 8 28 presented present VBN cord-027201-owzhv0xy 8 29 . . . cord-027201-owzhv0xy 9 1 Initially initially RB cord-027201-owzhv0xy 9 2 , , , cord-027201-owzhv0xy 9 3 when when WRB cord-027201-owzhv0xy 9 4 implementation implementation NN cord-027201-owzhv0xy 9 5 was be VBD cord-027201-owzhv0xy 9 6 made make VBN cord-027201-owzhv0xy 9 7 with with IN cord-027201-owzhv0xy 9 8 the the DT cord-027201-owzhv0xy 9 9 use use NN cord-027201-owzhv0xy 9 10 of of IN cord-027201-owzhv0xy 9 11 Cartesian Cartesian NNP cord-027201-owzhv0xy 9 12 Coordinates Coordinates NNPS cord-027201-owzhv0xy 9 13 , , , cord-027201-owzhv0xy 9 14 simulation simulation NN cord-027201-owzhv0xy 9 15 takes take VBZ cord-027201-owzhv0xy 9 16 a a DT cord-027201-owzhv0xy 9 17 lot lot NN cord-027201-owzhv0xy 9 18 of of IN cord-027201-owzhv0xy 9 19 time time NN cord-027201-owzhv0xy 9 20 to to TO cord-027201-owzhv0xy 9 21 create create VB cord-027201-owzhv0xy 9 22 a a DT cord-027201-owzhv0xy 9 23 model model NN cord-027201-owzhv0xy 9 24 ( ( -LRB- cord-027201-owzhv0xy 9 25 mean mean VB cord-027201-owzhv0xy 9 26 746.7[sec 746.7[sec CD cord-027201-owzhv0xy 9 27 ] ] -RRB- cord-027201-owzhv0xy 9 28 with with IN cord-027201-owzhv0xy 9 29 the the DT cord-027201-owzhv0xy 9 30 median median JJ cord-027201-owzhv0xy 9 31 569.1[sec 569.1[sec NN cord-027201-owzhv0xy 9 32 ] ] -RRB- cord-027201-owzhv0xy 9 33 ) ) -RRB- cord-027201-owzhv0xy 9 34 and and CC cord-027201-owzhv0xy 9 35 additionally additionally RB cord-027201-owzhv0xy 9 36 requires require VBZ cord-027201-owzhv0xy 9 37 restarts restart NNS cord-027201-owzhv0xy 9 38 of of IN cord-027201-owzhv0xy 9 39 the the DT cord-027201-owzhv0xy 9 40 algorithm algorithm NN cord-027201-owzhv0xy 9 41 , , , cord-027201-owzhv0xy 9 42 also also RB cord-027201-owzhv0xy 9 43 often often RB cord-027201-owzhv0xy 9 44 exceeds exceed VBZ cord-027201-owzhv0xy 9 45 acceptable acceptable JJ cord-027201-owzhv0xy 9 46 ( ( -LRB- cord-027201-owzhv0xy 9 47 given give VBN cord-027201-owzhv0xy 9 48 a a DT cord-027201-owzhv0xy 9 49 priori priori FW cord-027201-owzhv0xy 9 50 ) ) -RRB- cord-027201-owzhv0xy 9 51 time time NN cord-027201-owzhv0xy 9 52 for for IN cord-027201-owzhv0xy 9 53 the the DT cord-027201-owzhv0xy 9 54 computational computational JJ cord-027201-owzhv0xy 9 55 experiment experiment NN cord-027201-owzhv0xy 9 56 . . . cord-027201-owzhv0xy 10 1 Because because IN cord-027201-owzhv0xy 10 2 of of IN cord-027201-owzhv0xy 10 3 that that DT cord-027201-owzhv0xy 10 4 , , , cord-027201-owzhv0xy 10 5 authors author NNS cord-027201-owzhv0xy 10 6 attempted attempt VBD cord-027201-owzhv0xy 10 7 changing change VBG cord-027201-owzhv0xy 10 8 the the DT cord-027201-owzhv0xy 10 9 coordinate coordinate JJ cord-027201-owzhv0xy 10 10 system system NN cord-027201-owzhv0xy 10 11 to to IN cord-027201-owzhv0xy 10 12 Spherical Spherical NNP cord-027201-owzhv0xy 10 13 Coordinates Coordinates NNPS cord-027201-owzhv0xy 10 14 ( ( -LRB- cord-027201-owzhv0xy 10 15 in in IN cord-027201-owzhv0xy 10 16 a a DT cord-027201-owzhv0xy 10 17 few few JJ cord-027201-owzhv0xy 10 18 previous previous JJ cord-027201-owzhv0xy 10 19 projects project NNS cord-027201-owzhv0xy 10 20 it -PRON- PRP cord-027201-owzhv0xy 10 21 leads lead VBZ cord-027201-owzhv0xy 10 22 to to IN cord-027201-owzhv0xy 10 23 improving improve VBG cord-027201-owzhv0xy 10 24 the the DT cord-027201-owzhv0xy 10 25 efficiency efficiency NN cord-027201-owzhv0xy 10 26 of of IN cord-027201-owzhv0xy 10 27 implementation implementation NN cord-027201-owzhv0xy 10 28 ) ) -RRB- cord-027201-owzhv0xy 10 29 . . . cord-027201-owzhv0xy 11 1 After after IN cord-027201-owzhv0xy 11 2 changing change VBG cord-027201-owzhv0xy 11 3 the the DT cord-027201-owzhv0xy 11 4 way way NN cord-027201-owzhv0xy 11 5 that that WDT cord-027201-owzhv0xy 11 6 3D 3d JJ cord-027201-owzhv0xy 11 7 point point NN cord-027201-owzhv0xy 11 8 is be VBZ cord-027201-owzhv0xy 11 9 represented represent VBN cord-027201-owzhv0xy 11 10 in in IN cord-027201-owzhv0xy 11 11 3D 3d JJ cord-027201-owzhv0xy 11 12 space space NN cord-027201-owzhv0xy 11 13 the the DT cord-027201-owzhv0xy 11 14 time time NN cord-027201-owzhv0xy 11 15 required require VBN cord-027201-owzhv0xy 11 16 to to TO cord-027201-owzhv0xy 11 17 make make VB cord-027201-owzhv0xy 11 18 a a DT cord-027201-owzhv0xy 11 19 successful successful JJ cord-027201-owzhv0xy 11 20 model model NN cord-027201-owzhv0xy 11 21 reduced reduce VBN cord-027201-owzhv0xy 11 22 to to IN cord-027201-owzhv0xy 11 23 the the DT cord-027201-owzhv0xy 11 24 mean mean JJ cord-027201-owzhv0xy 11 25 25.3[sec 25.3[sec CD cord-027201-owzhv0xy 11 26 ] ] -RRB- cord-027201-owzhv0xy 11 27 with with IN cord-027201-owzhv0xy 11 28 a a DT cord-027201-owzhv0xy 11 29 median median JJ cord-027201-owzhv0xy 11 30 18.5[s 18.5[s CD cord-027201-owzhv0xy 11 31 ] ] -RRB- cord-027201-owzhv0xy 11 32 ( ( -LRB- cord-027201-owzhv0xy 11 33 alongside alongside RB cord-027201-owzhv0xy 11 34 with with IN cord-027201-owzhv0xy 11 35 lowering lower VBG cord-027201-owzhv0xy 11 36 the the DT cord-027201-owzhv0xy 11 37 number number NN cord-027201-owzhv0xy 11 38 of of IN cord-027201-owzhv0xy 11 39 necessary necessary JJ cord-027201-owzhv0xy 11 40 algorithm algorithm NN cord-027201-owzhv0xy 11 41 restarts restart VBZ cord-027201-owzhv0xy 11 42 ) ) -RRB- cord-027201-owzhv0xy 11 43 which which WDT cord-027201-owzhv0xy 11 44 gives give VBZ cord-027201-owzhv0xy 11 45 a a DT cord-027201-owzhv0xy 11 46 significant significant JJ cord-027201-owzhv0xy 11 47 difference difference NN cord-027201-owzhv0xy 11 48 in in IN cord-027201-owzhv0xy 11 49 the the DT cord-027201-owzhv0xy 11 50 efficiency efficiency NN cord-027201-owzhv0xy 11 51 of of IN cord-027201-owzhv0xy 11 52 model model NN cord-027201-owzhv0xy 11 53 ’s ’s POS cord-027201-owzhv0xy 11 54 creation creation NN cord-027201-owzhv0xy 11 55 . . . cord-027201-owzhv0xy 12 1 Therefore therefore RB cord-027201-owzhv0xy 12 2 we -PRON- PRP cord-027201-owzhv0xy 12 3 showed show VBD cord-027201-owzhv0xy 12 4 , , , cord-027201-owzhv0xy 12 5 that that IN cord-027201-owzhv0xy 12 6 a a DT cord-027201-owzhv0xy 12 7 more more RBR cord-027201-owzhv0xy 12 8 efficient efficient JJ cord-027201-owzhv0xy 12 9 way way NN cord-027201-owzhv0xy 12 10 for for IN cord-027201-owzhv0xy 12 11 implementation implementation NN cord-027201-owzhv0xy 12 12 was be VBD cord-027201-owzhv0xy 12 13 the the DT cord-027201-owzhv0xy 12 14 usage usage NN cord-027201-owzhv0xy 12 15 of of IN cord-027201-owzhv0xy 12 16 spherical spherical JJ cord-027201-owzhv0xy 12 17 coordinates coordinate NNS cord-027201-owzhv0xy 12 18 . . . cord-027201-owzhv0xy 13 1 Computational computational JJ cord-027201-owzhv0xy 13 2 power power NN cord-027201-owzhv0xy 13 3 gives give VBZ cord-027201-owzhv0xy 13 4 very very RB cord-027201-owzhv0xy 13 5 powerful powerful JJ cord-027201-owzhv0xy 13 6 support support NN cord-027201-owzhv0xy 13 7 in in IN cord-027201-owzhv0xy 13 8 the the DT cord-027201-owzhv0xy 13 9 life life NN cord-027201-owzhv0xy 13 10 sciences science NNS cord-027201-owzhv0xy 13 11 today today NN cord-027201-owzhv0xy 13 12 . . . cord-027201-owzhv0xy 14 1 A a DT cord-027201-owzhv0xy 14 2 lot lot NN cord-027201-owzhv0xy 14 3 of of IN cord-027201-owzhv0xy 14 4 experiments experiment NNS cord-027201-owzhv0xy 14 5 can can MD cord-027201-owzhv0xy 14 6 be be VB cord-027201-owzhv0xy 14 7 done do VBN cord-027201-owzhv0xy 14 8 -they -they : cord-027201-owzhv0xy 14 9 are be VBP cord-027201-owzhv0xy 14 10 cheaper cheap JJR cord-027201-owzhv0xy 14 11 to to TO cord-027201-owzhv0xy 14 12 conduct conduct VB cord-027201-owzhv0xy 14 13 , , , cord-027201-owzhv0xy 14 14 their -PRON- PRP$ cord-027201-owzhv0xy 14 15 parameters parameter NNS cord-027201-owzhv0xy 14 16 can can MD cord-027201-owzhv0xy 14 17 be be VB cord-027201-owzhv0xy 14 18 easily easily RB cord-027201-owzhv0xy 14 19 modified modify VBN cord-027201-owzhv0xy 14 20 . . . cord-027201-owzhv0xy 15 1 They -PRON- PRP cord-027201-owzhv0xy 15 2 are be VBP cord-027201-owzhv0xy 15 3 also also RB cord-027201-owzhv0xy 15 4 in in IN cord-027201-owzhv0xy 15 5 most most JJS cord-027201-owzhv0xy 15 6 cases case NNS cord-027201-owzhv0xy 15 7 reproducible reproducible JJ cord-027201-owzhv0xy 15 8 and and CC cord-027201-owzhv0xy 15 9 ethical ethical JJ cord-027201-owzhv0xy 15 10 ( ( -LRB- cord-027201-owzhv0xy 15 11 no no DT cord-027201-owzhv0xy 15 12 wronging wrong VBG cord-027201-owzhv0xy 15 13 living live VBG cord-027201-owzhv0xy 15 14 creatures creature NNS cord-027201-owzhv0xy 15 15 ) ) -RRB- cord-027201-owzhv0xy 15 16 . . . cord-027201-owzhv0xy 16 1 According accord VBG cord-027201-owzhv0xy 16 2 [ [ -LRB- cord-027201-owzhv0xy 16 3 1 1 CD cord-027201-owzhv0xy 16 4 ] ] -RRB- cord-027201-owzhv0xy 16 5 the the DT cord-027201-owzhv0xy 16 6 term term NN cord-027201-owzhv0xy 16 7 modeling modeling NN cord-027201-owzhv0xy 16 8 is be VBZ cord-027201-owzhv0xy 16 9 defined define VBN cord-027201-owzhv0xy 16 10 as as IN cord-027201-owzhv0xy 16 11 " " `` cord-027201-owzhv0xy 16 12 to to TO cord-027201-owzhv0xy 16 13 design design VB cord-027201-owzhv0xy 16 14 or or CC cord-027201-owzhv0xy 16 15 imitate imitate VB cord-027201-owzhv0xy 16 16 forms form NNS cord-027201-owzhv0xy 16 17 : : : cord-027201-owzhv0xy 16 18 make make VB cord-027201-owzhv0xy 16 19 a a DT cord-027201-owzhv0xy 16 20 pattern pattern NN cord-027201-owzhv0xy 16 21 " " '' cord-027201-owzhv0xy 16 22 or or CC cord-027201-owzhv0xy 16 23 " " `` cord-027201-owzhv0xy 16 24 producing produce VBG cord-027201-owzhv0xy 16 25 a a DT cord-027201-owzhv0xy 16 26 representation representation NN cord-027201-owzhv0xy 16 27 or or CC cord-027201-owzhv0xy 16 28 simulation simulation NN cord-027201-owzhv0xy 16 29 " " '' cord-027201-owzhv0xy 16 30 and and CC cord-027201-owzhv0xy 16 31 model model NN cord-027201-owzhv0xy 16 32 is be VBZ cord-027201-owzhv0xy 16 33 defined define VBN cord-027201-owzhv0xy 16 34 as as IN cord-027201-owzhv0xy 16 35 " " `` cord-027201-owzhv0xy 16 36 a a DT cord-027201-owzhv0xy 16 37 system system NN cord-027201-owzhv0xy 16 38 of of IN cord-027201-owzhv0xy 16 39 postulates postulate NNS cord-027201-owzhv0xy 16 40 , , , cord-027201-owzhv0xy 16 41 data datum NNS cord-027201-owzhv0xy 16 42 , , , cord-027201-owzhv0xy 16 43 and and CC cord-027201-owzhv0xy 16 44 inferences inference NNS cord-027201-owzhv0xy 16 45 presented present VBN cord-027201-owzhv0xy 16 46 as as IN cord-027201-owzhv0xy 16 47 a a DT cord-027201-owzhv0xy 16 48 mathematical mathematical JJ cord-027201-owzhv0xy 16 49 description description NN cord-027201-owzhv0xy 16 50 of of IN cord-027201-owzhv0xy 16 51 an an DT cord-027201-owzhv0xy 16 52 entity entity NN cord-027201-owzhv0xy 16 53 or or CC cord-027201-owzhv0xy 16 54 state state NN cord-027201-owzhv0xy 16 55 of of IN cord-027201-owzhv0xy 16 56 affairs affair NNS cord-027201-owzhv0xy 16 57 " " '' cord-027201-owzhv0xy 16 58 . . . cord-027201-owzhv0xy 17 1 In in IN cord-027201-owzhv0xy 17 2 fact fact NN cord-027201-owzhv0xy 17 3 , , , cord-027201-owzhv0xy 17 4 in in IN cord-027201-owzhv0xy 17 5 a a DT cord-027201-owzhv0xy 17 6 case case NN cord-027201-owzhv0xy 17 7 of of IN cord-027201-owzhv0xy 17 8 insilico insilico JJ cord-027201-owzhv0xy 17 9 experiments experiment NNS cord-027201-owzhv0xy 17 10 more more RBR cord-027201-owzhv0xy 17 11 precious precious JJ cord-027201-owzhv0xy 17 12 would would MD cord-027201-owzhv0xy 17 13 be be VB cord-027201-owzhv0xy 17 14 " " `` cord-027201-owzhv0xy 17 15 computational computational JJ cord-027201-owzhv0xy 17 16 model model NN cord-027201-owzhv0xy 17 17 " " '' cord-027201-owzhv0xy 17 18 and and CC cord-027201-owzhv0xy 17 19 " " `` cord-027201-owzhv0xy 17 20 computational computational JJ cord-027201-owzhv0xy 17 21 modeling modeling NN cord-027201-owzhv0xy 17 22 " " '' cord-027201-owzhv0xy 17 23 , , , cord-027201-owzhv0xy 17 24 but but CC cord-027201-owzhv0xy 17 25 in in IN cord-027201-owzhv0xy 17 26 this this DT cord-027201-owzhv0xy 17 27 paper paper NN cord-027201-owzhv0xy 17 28 , , , cord-027201-owzhv0xy 17 29 it -PRON- PRP cord-027201-owzhv0xy 17 30 will will MD cord-027201-owzhv0xy 17 31 be be VB cord-027201-owzhv0xy 17 32 referred refer VBN cord-027201-owzhv0xy 17 33 to to IN cord-027201-owzhv0xy 17 34 in in IN cord-027201-owzhv0xy 17 35 a a DT cord-027201-owzhv0xy 17 36 shorter short JJR cord-027201-owzhv0xy 17 37 form form NN cord-027201-owzhv0xy 17 38 . . . cord-027201-owzhv0xy 18 1 Sometimes sometimes RB cord-027201-owzhv0xy 18 2 term term NN cord-027201-owzhv0xy 18 3 " " `` cord-027201-owzhv0xy 18 4 modeling modeling NN cord-027201-owzhv0xy 18 5 " " '' cord-027201-owzhv0xy 18 6 is be VBZ cord-027201-owzhv0xy 18 7 used use VBN cord-027201-owzhv0xy 18 8 in in IN cord-027201-owzhv0xy 18 9 the the DT cord-027201-owzhv0xy 18 10 context context NN cord-027201-owzhv0xy 18 11 of of IN cord-027201-owzhv0xy 18 12 " " `` cord-027201-owzhv0xy 18 13 running run VBG cord-027201-owzhv0xy 18 14 computational computational JJ cord-027201-owzhv0xy 18 15 model model NN cord-027201-owzhv0xy 18 16 " " '' cord-027201-owzhv0xy 18 17 -but -but , cord-027201-owzhv0xy 18 18 in in IN cord-027201-owzhv0xy 18 19 this this DT cord-027201-owzhv0xy 18 20 paper paper NN cord-027201-owzhv0xy 18 21 , , , cord-027201-owzhv0xy 18 22 it -PRON- PRP cord-027201-owzhv0xy 18 23 will will MD cord-027201-owzhv0xy 18 24 be be VB cord-027201-owzhv0xy 18 25 referred refer VBN cord-027201-owzhv0xy 18 26 to to IN cord-027201-owzhv0xy 18 27 as as IN cord-027201-owzhv0xy 18 28 " " `` cord-027201-owzhv0xy 18 29 simulation simulation NN cord-027201-owzhv0xy 18 30 " " '' cord-027201-owzhv0xy 18 31 . . . cord-027201-owzhv0xy 19 1 For for IN cord-027201-owzhv0xy 19 2 many many JJ cord-027201-owzhv0xy 19 3 disciplines discipline NNS cord-027201-owzhv0xy 19 4 creating create VBG cord-027201-owzhv0xy 19 5 a a DT cord-027201-owzhv0xy 19 6 model model NN cord-027201-owzhv0xy 19 7 is be VBZ cord-027201-owzhv0xy 19 8 important important JJ cord-027201-owzhv0xy 19 9 -it -it : cord-027201-owzhv0xy 19 10 allows allow VBZ cord-027201-owzhv0xy 19 11 to to TO cord-027201-owzhv0xy 19 12 re re VB cord-027201-owzhv0xy 19 13 - - VB cord-027201-owzhv0xy 19 14 scale scale JJ cord-027201-owzhv0xy 19 15 ( ( -LRB- cord-027201-owzhv0xy 19 16 extend extend VB cord-027201-owzhv0xy 19 17 or or CC cord-027201-owzhv0xy 19 18 reduce reduce VB cord-027201-owzhv0xy 19 19 ) ) -RRB- cord-027201-owzhv0xy 19 20 object object NN cord-027201-owzhv0xy 19 21 , , , cord-027201-owzhv0xy 19 22 slow slow VB cord-027201-owzhv0xy 19 23 down down RP cord-027201-owzhv0xy 19 24 or or CC cord-027201-owzhv0xy 19 25 speed speed VB cord-027201-owzhv0xy 19 26 up up RP cord-027201-owzhv0xy 19 27 modeled model VBN cord-027201-owzhv0xy 19 28 process process NN cord-027201-owzhv0xy 19 29 , , , cord-027201-owzhv0xy 19 30 examine examine VB cord-027201-owzhv0xy 19 31 almost almost RB cord-027201-owzhv0xy 19 32 any any DT cord-027201-owzhv0xy 19 33 aspect aspect NN cord-027201-owzhv0xy 19 34 of of IN cord-027201-owzhv0xy 19 35 object object NN cord-027201-owzhv0xy 19 36 or or CC cord-027201-owzhv0xy 19 37 process process NN cord-027201-owzhv0xy 19 38 ( ( -LRB- cord-027201-owzhv0xy 19 39 separating separate VBG cord-027201-owzhv0xy 19 40 parameters parameter NNS cord-027201-owzhv0xy 19 41 or or CC cord-027201-owzhv0xy 19 42 taking take VBG cord-027201-owzhv0xy 19 43 into into IN cord-027201-owzhv0xy 19 44 account account NN cord-027201-owzhv0xy 19 45 a a DT cord-027201-owzhv0xy 19 46 given give VBN cord-027201-owzhv0xy 19 47 quantity quantity NN cord-027201-owzhv0xy 19 48 of of IN cord-027201-owzhv0xy 19 49 parameters parameter NNS cord-027201-owzhv0xy 19 50 ) ) -RRB- cord-027201-owzhv0xy 19 51 . . . cord-027201-owzhv0xy 20 1 With with IN cord-027201-owzhv0xy 20 2 the the DT cord-027201-owzhv0xy 20 3 use use NN cord-027201-owzhv0xy 20 4 of of IN cord-027201-owzhv0xy 20 5 computers computer NNS cord-027201-owzhv0xy 20 6 , , , cord-027201-owzhv0xy 20 7 it -PRON- PRP cord-027201-owzhv0xy 20 8 is be VBZ cord-027201-owzhv0xy 20 9 also also RB cord-027201-owzhv0xy 20 10 possible possible JJ cord-027201-owzhv0xy 20 11 to to TO cord-027201-owzhv0xy 20 12 make make VB cord-027201-owzhv0xy 20 13 visualizations visualization NNS cord-027201-owzhv0xy 20 14 and and CC cord-027201-owzhv0xy 20 15 animations animation NNS cord-027201-owzhv0xy 20 16 . . . cord-027201-owzhv0xy 21 1 This this DT cord-027201-owzhv0xy 21 2 paper paper NN cord-027201-owzhv0xy 21 3 describes describe VBZ cord-027201-owzhv0xy 21 4 some some DT cord-027201-owzhv0xy 21 5 aspects aspect NNS cord-027201-owzhv0xy 21 6 of of IN cord-027201-owzhv0xy 21 7 the the DT cord-027201-owzhv0xy 21 8 modeling modeling NN cord-027201-owzhv0xy 21 9 process process NN cord-027201-owzhv0xy 21 10 that that WDT cord-027201-owzhv0xy 21 11 occurs occur VBZ cord-027201-owzhv0xy 21 12 in in IN cord-027201-owzhv0xy 21 13 all all DT cord-027201-owzhv0xy 21 14 organisms organism NNS cord-027201-owzhv0xy 21 15 -precisely -precisely RB cord-027201-owzhv0xy 21 16 speaking speak VBG cord-027201-owzhv0xy 21 17 occurs occur VBZ cord-027201-owzhv0xy 21 18 in in IN cord-027201-owzhv0xy 21 19 almost almost RB cord-027201-owzhv0xy 21 20 every every DT cord-027201-owzhv0xy 21 21 living live VBG cord-027201-owzhv0xy 21 22 cell cell NN cord-027201-owzhv0xy 21 23 . . . cord-027201-owzhv0xy 22 1 This this DT cord-027201-owzhv0xy 22 2 process process NN cord-027201-owzhv0xy 22 3 also also RB cord-027201-owzhv0xy 22 4 occurs occur VBZ cord-027201-owzhv0xy 22 5 just just RB cord-027201-owzhv0xy 22 6 right right RB cord-027201-owzhv0xy 22 7 now now RB cord-027201-owzhv0xy 22 8 -in -in . cord-027201-owzhv0xy 22 9 my -PRON- PRP$ cord-027201-owzhv0xy 22 10 body body NN cord-027201-owzhv0xy 22 11 while while IN cord-027201-owzhv0xy 22 12 I -PRON- PRP cord-027201-owzhv0xy 22 13 'm be VBP cord-027201-owzhv0xy 22 14 writing write VBG cord-027201-owzhv0xy 22 15 this this DT cord-027201-owzhv0xy 22 16 text text NN cord-027201-owzhv0xy 22 17 , , , cord-027201-owzhv0xy 22 18 as as RB cord-027201-owzhv0xy 22 19 well well RB cord-027201-owzhv0xy 22 20 as as IN cord-027201-owzhv0xy 22 21 in in IN cord-027201-owzhv0xy 22 22 your -PRON- PRP$ cord-027201-owzhv0xy 22 23 -when -when . cord-027201-owzhv0xy 23 1 you -PRON- PRP cord-027201-owzhv0xy 23 2 read read VBP cord-027201-owzhv0xy 23 3 this this DT cord-027201-owzhv0xy 23 4 . . . cord-027201-owzhv0xy 24 1 This this DT cord-027201-owzhv0xy 24 2 is be VBZ cord-027201-owzhv0xy 24 3 the the DT cord-027201-owzhv0xy 24 4 process process NN cord-027201-owzhv0xy 24 5 of of IN cord-027201-owzhv0xy 24 6 transferring transfer VBG cord-027201-owzhv0xy 24 7 genetic genetic JJ cord-027201-owzhv0xy 24 8 material material NN cord-027201-owzhv0xy 24 9 , , , cord-027201-owzhv0xy 24 10 DNA dna NN cord-027201-owzhv0xy 24 11 - - HYPH cord-027201-owzhv0xy 24 12 during during IN cord-027201-owzhv0xy 24 13 cell cell NN cord-027201-owzhv0xy 24 14 division division NN cord-027201-owzhv0xy 24 15 . . . cord-027201-owzhv0xy 25 1 This this DT cord-027201-owzhv0xy 25 2 process process NN cord-027201-owzhv0xy 25 3 is be VBZ cord-027201-owzhv0xy 25 4 difficult difficult JJ cord-027201-owzhv0xy 25 5 to to TO cord-027201-owzhv0xy 25 6 examine examine VB cord-027201-owzhv0xy 25 7 -we -we : cord-027201-owzhv0xy 25 8 can can MD cord-027201-owzhv0xy 25 9 only only RB cord-027201-owzhv0xy 25 10 observe observe VB cord-027201-owzhv0xy 25 11 living living NN cord-027201-owzhv0xy 25 12 cells cell NNS cord-027201-owzhv0xy 25 13 during during IN cord-027201-owzhv0xy 25 14 a a DT cord-027201-owzhv0xy 25 15 relatively relatively RB cord-027201-owzhv0xy 25 16 short short JJ cord-027201-owzhv0xy 25 17 time time NN cord-027201-owzhv0xy 25 18 . . . cord-027201-owzhv0xy 26 1 Another another DT cord-027201-owzhv0xy 26 2 difficulty difficulty NN cord-027201-owzhv0xy 26 3 here here RB cord-027201-owzhv0xy 26 4 is be VBZ cord-027201-owzhv0xy 26 5 its -PRON- PRP$ cord-027201-owzhv0xy 26 6 microscale microscale JJ cord-027201-owzhv0xy 26 7 -to -to : cord-027201-owzhv0xy 26 8 observe observe VBP cord-027201-owzhv0xy 26 9 it -PRON- PRP cord-027201-owzhv0xy 26 10 we -PRON- PRP cord-027201-owzhv0xy 26 11 have have VBP cord-027201-owzhv0xy 26 12 to to TO cord-027201-owzhv0xy 26 13 use use VB cord-027201-owzhv0xy 26 14 microscopes microscope NNS cord-027201-owzhv0xy 26 15 . . . cord-027201-owzhv0xy 27 1 And and CC cord-027201-owzhv0xy 27 2 , , , cord-027201-owzhv0xy 27 3 besides besides IN cord-027201-owzhv0xy 27 4 of of IN cord-027201-owzhv0xy 27 5 a a DT cord-027201-owzhv0xy 27 6 scalewhen scalewhen NN cord-027201-owzhv0xy 27 7 we -PRON- PRP cord-027201-owzhv0xy 27 8 want want VBP cord-027201-owzhv0xy 27 9 to to TO cord-027201-owzhv0xy 27 10 examine examine VB cord-027201-owzhv0xy 27 11 the the DT cord-027201-owzhv0xy 27 12 interior interior NN cord-027201-owzhv0xy 27 13 of of IN cord-027201-owzhv0xy 27 14 the the DT cord-027201-owzhv0xy 27 15 cell cell NN cord-027201-owzhv0xy 27 16 -we -we : cord-027201-owzhv0xy 27 17 have have VBP cord-027201-owzhv0xy 27 18 to to TO cord-027201-owzhv0xy 27 19 destroy destroy VB cord-027201-owzhv0xy 27 20 ( ( -LRB- cord-027201-owzhv0xy 27 21 and and CC cord-027201-owzhv0xy 27 22 kill kill VB cord-027201-owzhv0xy 27 23 ) ) -RRB- cord-027201-owzhv0xy 27 24 it -PRON- PRP cord-027201-owzhv0xy 27 25 . . . cord-027201-owzhv0xy 27 26 . . . cord-027201-owzhv0xy 27 27 . . . cord-027201-owzhv0xy 28 1 There there EX cord-027201-owzhv0xy 28 2 are be VBP cord-027201-owzhv0xy 28 3 attempts attempt NNS cord-027201-owzhv0xy 28 4 to to TO cord-027201-owzhv0xy 28 5 create create VB cord-027201-owzhv0xy 28 6 an an DT cord-027201-owzhv0xy 28 7 " " `` cord-027201-owzhv0xy 28 8 artificial artificial JJ cord-027201-owzhv0xy 28 9 " " '' cord-027201-owzhv0xy 28 10 [ [ -LRB- cord-027201-owzhv0xy 28 11 2 2 CD cord-027201-owzhv0xy 28 12 ] ] -RRB- cord-027201-owzhv0xy 28 13 ( ( -LRB- cord-027201-owzhv0xy 28 14 or or CC cord-027201-owzhv0xy 28 15 " " `` cord-027201-owzhv0xy 28 16 synthetic synthetic JJ cord-027201-owzhv0xy 28 17 " " '' cord-027201-owzhv0xy 28 18 [ [ -LRB- cord-027201-owzhv0xy 28 19 3 3 CD cord-027201-owzhv0xy 28 20 ] ] -RRB- cord-027201-owzhv0xy 28 21 ) ) -RRB- cord-027201-owzhv0xy 28 22 cell cell NN cord-027201-owzhv0xy 28 23 , , , cord-027201-owzhv0xy 28 24 but but CC cord-027201-owzhv0xy 28 25 this this DT cord-027201-owzhv0xy 28 26 is be VBZ cord-027201-owzhv0xy 28 27 not not RB cord-027201-owzhv0xy 28 28 an an DT cord-027201-owzhv0xy 28 29 easy easy JJ cord-027201-owzhv0xy 28 30 task task NN cord-027201-owzhv0xy 28 31 . . . cord-027201-owzhv0xy 29 1 To to TO cord-027201-owzhv0xy 29 2 face face VB cord-027201-owzhv0xy 29 3 this this DT cord-027201-owzhv0xy 29 4 up up RP cord-027201-owzhv0xy 29 5 , , , cord-027201-owzhv0xy 29 6 using use VBG cord-027201-owzhv0xy 29 7 " " `` cord-027201-owzhv0xy 29 8 divide divide VB cord-027201-owzhv0xy 29 9 and and CC cord-027201-owzhv0xy 29 10 conquer conquer VB cord-027201-owzhv0xy 29 11 " " `` cord-027201-owzhv0xy 29 12 strategy strategy NN cord-027201-owzhv0xy 29 13 there there EX cord-027201-owzhv0xy 29 14 are be VBP cord-027201-owzhv0xy 29 15 attempts attempt NNS cord-027201-owzhv0xy 29 16 to to TO cord-027201-owzhv0xy 29 17 create create VB cord-027201-owzhv0xy 29 18 models model NNS cord-027201-owzhv0xy 29 19 of of IN cord-027201-owzhv0xy 29 20 certain certain JJ cord-027201-owzhv0xy 29 21 cell cell NN cord-027201-owzhv0xy 29 22 components component NNS cord-027201-owzhv0xy 29 23 and and CC cord-027201-owzhv0xy 29 24 processes process NNS cord-027201-owzhv0xy 29 25 . . . cord-027201-owzhv0xy 30 1 This this DT cord-027201-owzhv0xy 30 2 paper paper NN cord-027201-owzhv0xy 30 3 shows show VBZ cord-027201-owzhv0xy 30 4 some some DT cord-027201-owzhv0xy 30 5 new new JJ cord-027201-owzhv0xy 30 6 knowledge knowledge NN cord-027201-owzhv0xy 30 7 that that WDT cord-027201-owzhv0xy 30 8 we -PRON- PRP cord-027201-owzhv0xy 30 9 discover discover VBP cord-027201-owzhv0xy 30 10 while while IN cord-027201-owzhv0xy 30 11 trying try VBG cord-027201-owzhv0xy 30 12 to to TO cord-027201-owzhv0xy 30 13 model model VB cord-027201-owzhv0xy 30 14 chromosome chromosome NN cord-027201-owzhv0xy 30 15 territories territory NNS cord-027201-owzhv0xy 30 16 ( ( -LRB- cord-027201-owzhv0xy 31 1 CT CT NNP cord-027201-owzhv0xy 31 2 's 's POS cord-027201-owzhv0xy 31 3 ) ) -RRB- cord-027201-owzhv0xy 31 4 being be VBG cord-027201-owzhv0xy 31 5 a a DT cord-027201-owzhv0xy 31 6 final final JJ cord-027201-owzhv0xy 31 7 result result NN cord-027201-owzhv0xy 31 8 of of IN cord-027201-owzhv0xy 31 9 modeling modeling NN cord-027201-owzhv0xy 31 10 and and CC cord-027201-owzhv0xy 31 11 simulation simulation NN cord-027201-owzhv0xy 31 12 chromatin chromatin NN cord-027201-owzhv0xy 31 13 decondensation decondensation NN cord-027201-owzhv0xy 31 14 ( ( -LRB- cord-027201-owzhv0xy 31 15 CD CD NNP cord-027201-owzhv0xy 31 16 ) ) -RRB- cord-027201-owzhv0xy 31 17 process process NN cord-027201-owzhv0xy 31 18 and and CC cord-027201-owzhv0xy 31 19 documents document NNS cord-027201-owzhv0xy 31 20 some some DT cord-027201-owzhv0xy 31 21 problems problem NNS cord-027201-owzhv0xy 31 22 ( ( -LRB- cord-027201-owzhv0xy 31 23 and and CC cord-027201-owzhv0xy 31 24 the the DT cord-027201-owzhv0xy 31 25 way way NN cord-027201-owzhv0xy 31 26 we -PRON- PRP cord-027201-owzhv0xy 31 27 took take VBD cord-027201-owzhv0xy 31 28 to to TO cord-027201-owzhv0xy 31 29 solve solve VB cord-027201-owzhv0xy 31 30 them -PRON- PRP cord-027201-owzhv0xy 31 31 ) ) -RRB- cord-027201-owzhv0xy 31 32 to to TO cord-027201-owzhv0xy 31 33 make make VB cord-027201-owzhv0xy 31 34 the the DT cord-027201-owzhv0xy 31 35 working working NN cord-027201-owzhv0xy 31 36 model model NN cord-027201-owzhv0xy 31 37 . . . cord-027201-owzhv0xy 32 1 Some some DT cord-027201-owzhv0xy 32 2 time time NN cord-027201-owzhv0xy 32 3 ago ago RB cord-027201-owzhv0xy 32 4 we -PRON- PRP cord-027201-owzhv0xy 32 5 are be VBP cord-027201-owzhv0xy 32 6 asked ask VBN cord-027201-owzhv0xy 32 7 if if IN cord-027201-owzhv0xy 32 8 we -PRON- PRP cord-027201-owzhv0xy 32 9 can can MD cord-027201-owzhv0xy 32 10 help help VB cord-027201-owzhv0xy 32 11 in in IN cord-027201-owzhv0xy 32 12 the the DT cord-027201-owzhv0xy 32 13 creation creation NN cord-027201-owzhv0xy 32 14 of of IN cord-027201-owzhv0xy 32 15 a a DT cord-027201-owzhv0xy 32 16 probabilistic probabilistic JJ cord-027201-owzhv0xy 32 17 model model NN cord-027201-owzhv0xy 32 18 of of IN cord-027201-owzhv0xy 32 19 CT CT NNP cord-027201-owzhv0xy 32 20 's 's POS cord-027201-owzhv0xy 32 21 ( ( -LRB- cord-027201-owzhv0xy 32 22 in in IN cord-027201-owzhv0xy 32 23 short short JJ cord-027201-owzhv0xy 32 24 -CT -ct NN cord-027201-owzhv0xy 32 25 's 's POS cord-027201-owzhv0xy 33 1 are be VBP cord-027201-owzhv0xy 33 2 the the DT cord-027201-owzhv0xy 33 3 distinct distinct JJ cord-027201-owzhv0xy 33 4 3D 3d JJ cord-027201-owzhv0xy 33 5 space space NN cord-027201-owzhv0xy 33 6 occupied occupy VBN cord-027201-owzhv0xy 33 7 by by IN cord-027201-owzhv0xy 33 8 each each DT cord-027201-owzhv0xy 33 9 chromosome chromosome NN cord-027201-owzhv0xy 33 10 after after IN cord-027201-owzhv0xy 33 11 cell cell NN cord-027201-owzhv0xy 33 12 division division NN cord-027201-owzhv0xy 33 13 , , , cord-027201-owzhv0xy 33 14 see see VB cord-027201-owzhv0xy 33 15 also also RB cord-027201-owzhv0xy 33 16 Sect Sect NNP cord-027201-owzhv0xy 33 17 . . . cord-027201-owzhv0xy 34 1 1.2 1.2 CD cord-027201-owzhv0xy 34 2 ) ) -RRB- cord-027201-owzhv0xy 34 3 . . . cord-027201-owzhv0xy 35 1 We -PRON- PRP cord-027201-owzhv0xy 35 2 agreed agree VBD cord-027201-owzhv0xy 35 3 and and CC cord-027201-owzhv0xy 35 4 something something NN cord-027201-owzhv0xy 35 5 that that WDT cord-027201-owzhv0xy 35 6 we -PRON- PRP cord-027201-owzhv0xy 35 7 supposed suppose VBD cord-027201-owzhv0xy 35 8 to to TO cord-027201-owzhv0xy 35 9 be be VB cord-027201-owzhv0xy 35 10 a a DT cord-027201-owzhv0xy 35 11 project project NN cord-027201-owzhv0xy 35 12 for for IN cord-027201-owzhv0xy 35 13 a a DT cord-027201-owzhv0xy 35 14 few few JJ cord-027201-owzhv0xy 35 15 months month NNS cord-027201-owzhv0xy 35 16 of of IN cord-027201-owzhv0xy 35 17 work work NN cord-027201-owzhv0xy 35 18 , , , cord-027201-owzhv0xy 35 19 becomes become VBZ cord-027201-owzhv0xy 35 20 the the DT cord-027201-owzhv0xy 35 21 true true JJ cord-027201-owzhv0xy 35 22 mine mine NN cord-027201-owzhv0xy 35 23 of of IN cord-027201-owzhv0xy 35 24 many many JJ cord-027201-owzhv0xy 35 25 different different JJ cord-027201-owzhv0xy 35 26 problems problem NNS cord-027201-owzhv0xy 35 27 to to TO cord-027201-owzhv0xy 35 28 be be VB cord-027201-owzhv0xy 35 29 solved solve VBN cord-027201-owzhv0xy 35 30 . . . cord-027201-owzhv0xy 36 1 The the DT cord-027201-owzhv0xy 36 2 first first JJ cord-027201-owzhv0xy 36 3 one one NN cord-027201-owzhv0xy 36 4 we -PRON- PRP cord-027201-owzhv0xy 36 5 focused focus VBD cord-027201-owzhv0xy 36 6 on on IN cord-027201-owzhv0xy 36 7 , , , cord-027201-owzhv0xy 36 8 was be VBD cord-027201-owzhv0xy 36 9 the the DT cord-027201-owzhv0xy 36 10 problem problem NN cord-027201-owzhv0xy 36 11 of of IN cord-027201-owzhv0xy 36 12 creating create VBG cord-027201-owzhv0xy 36 13 appropriate appropriate JJ cord-027201-owzhv0xy 36 14 model model NN cord-027201-owzhv0xy 36 15 of of IN cord-027201-owzhv0xy 36 16 chromatin chromatin NN cord-027201-owzhv0xy 36 17 and and CC cord-027201-owzhv0xy 36 18 the the DT cord-027201-owzhv0xy 36 19 model model NN cord-027201-owzhv0xy 36 20 of of IN cord-027201-owzhv0xy 36 21 the the DT cord-027201-owzhv0xy 36 22 chromatin chromatin NN cord-027201-owzhv0xy 36 23 decondensation decondensation NN cord-027201-owzhv0xy 36 24 process process NN cord-027201-owzhv0xy 36 25 ( ( -LRB- cord-027201-owzhv0xy 36 26 to to TO cord-027201-owzhv0xy 36 27 be be VB cord-027201-owzhv0xy 36 28 able able JJ cord-027201-owzhv0xy 36 29 to to TO cord-027201-owzhv0xy 36 30 implement implement VB cord-027201-owzhv0xy 36 31 and and CC cord-027201-owzhv0xy 36 32 simulate simulate VB cord-027201-owzhv0xy 36 33 this this DT cord-027201-owzhv0xy 36 34 process process NN cord-027201-owzhv0xy 36 35 ) ) -RRB- cord-027201-owzhv0xy 36 36 in in IN cord-027201-owzhv0xy 36 37 a a DT cord-027201-owzhv0xy 36 38 phase phase NN cord-027201-owzhv0xy 36 39 just just RB cord-027201-owzhv0xy 36 40 right right RB cord-027201-owzhv0xy 36 41 after after IN cord-027201-owzhv0xy 36 42 cell cell NN cord-027201-owzhv0xy 36 43 division division NN cord-027201-owzhv0xy 36 44 . . . cord-027201-owzhv0xy 37 1 In in IN cord-027201-owzhv0xy 37 2 eukaryotic eukaryotic JJ cord-027201-owzhv0xy 37 3 cells cell NNS cord-027201-owzhv0xy 37 4 , , , cord-027201-owzhv0xy 37 5 genetic genetic JJ cord-027201-owzhv0xy 37 6 material material NN cord-027201-owzhv0xy 37 7 is be VBZ cord-027201-owzhv0xy 37 8 not not RB cord-027201-owzhv0xy 37 9 stored store VBN cord-027201-owzhv0xy 37 10 in in IN cord-027201-owzhv0xy 37 11 a a DT cord-027201-owzhv0xy 37 12 well well RB cord-027201-owzhv0xy 37 13 - - HYPH cord-027201-owzhv0xy 37 14 known know VBN cord-027201-owzhv0xy 37 15 form form NN cord-027201-owzhv0xy 37 16 of of IN cord-027201-owzhv0xy 37 17 a a DT cord-027201-owzhv0xy 37 18 helix helix NN cord-027201-owzhv0xy 37 19 because because IN cord-027201-owzhv0xy 37 20 DNA dna NN cord-027201-owzhv0xy 37 21 strand strand NN cord-027201-owzhv0xy 37 22 is be VBZ cord-027201-owzhv0xy 37 23 too too RB cord-027201-owzhv0xy 37 24 long long JJ cord-027201-owzhv0xy 37 25 ( ( -LRB- cord-027201-owzhv0xy 37 26 and and CC cord-027201-owzhv0xy 37 27 too too RB cord-027201-owzhv0xy 37 28 vulnerable vulnerable JJ cord-027201-owzhv0xy 37 29 to to IN cord-027201-owzhv0xy 37 30 damage damage NN cord-027201-owzhv0xy 37 31 ) ) -RRB- cord-027201-owzhv0xy 37 32 . . . cord-027201-owzhv0xy 38 1 It -PRON- PRP cord-027201-owzhv0xy 38 2 is be VBZ cord-027201-owzhv0xy 38 3 stored store VBN cord-027201-owzhv0xy 38 4 as as IN cord-027201-owzhv0xy 38 5 a a DT cord-027201-owzhv0xy 38 6 complex complex NN cord-027201-owzhv0xy 38 7 of of IN cord-027201-owzhv0xy 38 8 DNA dna NN cord-027201-owzhv0xy 38 9 strand strand NN cord-027201-owzhv0xy 38 10 and and CC cord-027201-owzhv0xy 38 11 proteins protein VBZ cord-027201-owzhv0xy 38 12 -altogether -altogether : cord-027201-owzhv0xy 38 13 called call VBN cord-027201-owzhv0xy 38 14 chromatin chromatin NN cord-027201-owzhv0xy 38 15 which which WDT cord-027201-owzhv0xy 38 16 is be VBZ cord-027201-owzhv0xy 38 17 being be VBG cord-027201-owzhv0xy 38 18 rolled roll VBN cord-027201-owzhv0xy 38 19 - - HYPH cord-027201-owzhv0xy 38 20 up up NN cord-027201-owzhv0xy 38 21 in in IN cord-027201-owzhv0xy 38 22 a a DT cord-027201-owzhv0xy 38 23 very very RB cord-027201-owzhv0xy 38 24 sophisticated sophisticated JJ cord-027201-owzhv0xy 38 25 way way NN cord-027201-owzhv0xy 38 26 [ [ -LRB- cord-027201-owzhv0xy 38 27 5 5 CD cord-027201-owzhv0xy 38 28 ] ] -RRB- cord-027201-owzhv0xy 38 29 . . . cord-027201-owzhv0xy 39 1 This this DT cord-027201-owzhv0xy 39 2 allows allow VBZ cord-027201-owzhv0xy 39 3 taking take VBG cord-027201-owzhv0xy 39 4 much much RB cord-027201-owzhv0xy 39 5 less less JJR cord-027201-owzhv0xy 39 6 space space NN cord-027201-owzhv0xy 39 7 and and CC cord-027201-owzhv0xy 39 8 store store NN cord-027201-owzhv0xy 39 9 DNA dna NN cord-027201-owzhv0xy 39 10 untangled untangle VBN cord-027201-owzhv0xy 39 11 . . . cord-027201-owzhv0xy 40 1 Probably probably RB cord-027201-owzhv0xy 40 2 it -PRON- PRP cord-027201-owzhv0xy 40 3 also also RB cord-027201-owzhv0xy 40 4 helps help VBZ cord-027201-owzhv0xy 40 5 in in IN cord-027201-owzhv0xy 40 6 preventing prevent VBG cord-027201-owzhv0xy 40 7 random random JJ cord-027201-owzhv0xy 40 8 breaks break NNS cord-027201-owzhv0xy 40 9 and and CC cord-027201-owzhv0xy 40 10 changes change NNS cord-027201-owzhv0xy 40 11 in in IN cord-027201-owzhv0xy 40 12 DNA dna NN cord-027201-owzhv0xy 40 13 sequences sequence NNS cord-027201-owzhv0xy 40 14 . . . cord-027201-owzhv0xy 41 1 Researches research NNS cord-027201-owzhv0xy 41 2 concerning concern VBG cord-027201-owzhv0xy 41 3 chromatin chromatin NN cord-027201-owzhv0xy 41 4 organization organization NN cord-027201-owzhv0xy 41 5 are be VBP cord-027201-owzhv0xy 41 6 important important JJ cord-027201-owzhv0xy 41 7 because because IN cord-027201-owzhv0xy 41 8 of of IN cord-027201-owzhv0xy 41 9 its -PRON- PRP$ cord-027201-owzhv0xy 41 10 influence influence NN cord-027201-owzhv0xy 41 11 on on IN cord-027201-owzhv0xy 41 12 gene gene NN cord-027201-owzhv0xy 41 13 transcription transcription NN cord-027201-owzhv0xy 41 14 [ [ -LRB- cord-027201-owzhv0xy 41 15 6 6 CD cord-027201-owzhv0xy 41 16 ] ] -RRB- cord-027201-owzhv0xy 41 17 . . . cord-027201-owzhv0xy 42 1 There there EX cord-027201-owzhv0xy 42 2 are be VBP cord-027201-owzhv0xy 42 3 levels level NNS cord-027201-owzhv0xy 42 4 of of IN cord-027201-owzhv0xy 42 5 chromatin chromatin NN cord-027201-owzhv0xy 42 6 organization organization NN cord-027201-owzhv0xy 42 7 ( ( -LRB- cord-027201-owzhv0xy 42 8 depending depend VBG cord-027201-owzhv0xy 42 9 on on IN cord-027201-owzhv0xy 42 10 the the DT cord-027201-owzhv0xy 42 11 level level NN cord-027201-owzhv0xy 42 12 of of IN cord-027201-owzhv0xy 42 13 packing packing NN cord-027201-owzhv0xy 42 14 ) ) -RRB- cord-027201-owzhv0xy 42 15 ( ( -LRB- cord-027201-owzhv0xy 42 16 [ [ -LRB- cord-027201-owzhv0xy 42 17 4 4 CD cord-027201-owzhv0xy 42 18 , , , cord-027201-owzhv0xy 42 19 7 7 CD cord-027201-owzhv0xy 42 20 ] ] -RRB- cord-027201-owzhv0xy 42 21 ) ) -RRB- cord-027201-owzhv0xy 42 22 . . . cord-027201-owzhv0xy 43 1 The the DT cord-027201-owzhv0xy 43 2 two two CD cord-027201-owzhv0xy 43 3 extreme extreme JJ cord-027201-owzhv0xy 43 4 levels level NNS cord-027201-owzhv0xy 43 5 of of IN cord-027201-owzhv0xy 43 6 packing packing NN cord-027201-owzhv0xy 43 7 are be VBP cord-027201-owzhv0xy 43 8 condensed condense VBN cord-027201-owzhv0xy 43 9 and and CC cord-027201-owzhv0xy 43 10 decondensed decondense VBN cord-027201-owzhv0xy 43 11 ones one NNS cord-027201-owzhv0xy 43 12 [ [ -LRB- cord-027201-owzhv0xy 43 13 11 11 CD cord-027201-owzhv0xy 43 14 ] ] -RRB- cord-027201-owzhv0xy 43 15 . . . cord-027201-owzhv0xy 44 1 The the DT cord-027201-owzhv0xy 44 2 one one CD cord-027201-owzhv0xy 44 3 -somewhere -somewhere NN cord-027201-owzhv0xy 45 1 in in IN cord-027201-owzhv0xy 45 2 between between IN cord-027201-owzhv0xy 45 3 extreme extreme JJ cord-027201-owzhv0xy 45 4 ones one NNS cord-027201-owzhv0xy 45 5 , , , cord-027201-owzhv0xy 45 6 that that IN cord-027201-owzhv0xy 45 7 we -PRON- PRP cord-027201-owzhv0xy 45 8 are be VBP cord-027201-owzhv0xy 45 9 interested interested JJ cord-027201-owzhv0xy 45 10 in in IN cord-027201-owzhv0xy 45 11 , , , cord-027201-owzhv0xy 45 12 is be VBZ cord-027201-owzhv0xy 45 13 called call VBN cord-027201-owzhv0xy 45 14 euchromatin euchromatin NN cord-027201-owzhv0xy 45 15 . . . cord-027201-owzhv0xy 46 1 This this DT cord-027201-owzhv0xy 46 2 level level NN cord-027201-owzhv0xy 46 3 of of IN cord-027201-owzhv0xy 46 4 organization organization NN cord-027201-owzhv0xy 46 5 is be VBZ cord-027201-owzhv0xy 46 6 often often RB cord-027201-owzhv0xy 46 7 referred refer VBN cord-027201-owzhv0xy 46 8 to to IN cord-027201-owzhv0xy 46 9 as as IN cord-027201-owzhv0xy 46 10 " " `` cord-027201-owzhv0xy 46 11 beads bead NNS cord-027201-owzhv0xy 46 12 on on IN cord-027201-owzhv0xy 46 13 a a DT cord-027201-owzhv0xy 46 14 strand strand NN cord-027201-owzhv0xy 46 15 " " '' cord-027201-owzhv0xy 46 16 ( ( -LRB- cord-027201-owzhv0xy 46 17 see see VB cord-027201-owzhv0xy 46 18 Fig Fig NNP cord-027201-owzhv0xy 46 19 . . NNP cord-027201-owzhv0xy 46 20 1 1 CD cord-027201-owzhv0xy 46 21 ) ) -RRB- cord-027201-owzhv0xy 46 22 . . . cord-027201-owzhv0xy 47 1 The the DT cord-027201-owzhv0xy 47 2 level level NN cord-027201-owzhv0xy 47 3 of of IN cord-027201-owzhv0xy 47 4 chromatin chromatin NN cord-027201-owzhv0xy 47 5 condensation condensation NN cord-027201-owzhv0xy 47 6 depends depend VBZ cord-027201-owzhv0xy 47 7 on on IN cord-027201-owzhv0xy 47 8 different different JJ cord-027201-owzhv0xy 47 9 factors factor NNS cord-027201-owzhv0xy 47 10 . . . cord-027201-owzhv0xy 48 1 It -PRON- PRP cord-027201-owzhv0xy 48 2 can can MD cord-027201-owzhv0xy 48 3 be be VB cord-027201-owzhv0xy 48 4 cell cell NN cord-027201-owzhv0xy 48 5 state state NN cord-027201-owzhv0xy 48 6 ( ( -LRB- cord-027201-owzhv0xy 48 7 during during IN cord-027201-owzhv0xy 48 8 cell cell NN cord-027201-owzhv0xy 48 9 cycle cycle NN cord-027201-owzhv0xy 48 10 ) ) -RRB- cord-027201-owzhv0xy 48 11 but but CC cord-027201-owzhv0xy 48 12 it -PRON- PRP cord-027201-owzhv0xy 48 13 is be VBZ cord-027201-owzhv0xy 48 14 also also RB cord-027201-owzhv0xy 48 15 known know VBN cord-027201-owzhv0xy 48 16 that that IN cord-027201-owzhv0xy 48 17 it -PRON- PRP cord-027201-owzhv0xy 48 18 can can MD cord-027201-owzhv0xy 48 19 be be VB cord-027201-owzhv0xy 48 20 controlled control VBN cord-027201-owzhv0xy 48 21 by by IN cord-027201-owzhv0xy 48 22 epigenetic epigenetic JJ cord-027201-owzhv0xy 48 23 modifications modification NNS cord-027201-owzhv0xy 48 24 [ [ -LRB- cord-027201-owzhv0xy 48 25 8 8 CD cord-027201-owzhv0xy 48 26 ] ] -RRB- cord-027201-owzhv0xy 48 27 or or CC cord-027201-owzhv0xy 48 28 biological biological JJ cord-027201-owzhv0xy 48 29 process process NN cord-027201-owzhv0xy 48 30 [ [ -LRB- cord-027201-owzhv0xy 48 31 10 10 CD cord-027201-owzhv0xy 48 32 ] ] -RRB- cord-027201-owzhv0xy 48 33 . . . cord-027201-owzhv0xy 49 1 The the DT cord-027201-owzhv0xy 49 2 risk risk NN cord-027201-owzhv0xy 49 3 of of IN cord-027201-owzhv0xy 49 4 DNA dna NN cord-027201-owzhv0xy 49 5 damage damage NN cord-027201-owzhv0xy 49 6 [ [ -LRB- cord-027201-owzhv0xy 49 7 9 9 CD cord-027201-owzhv0xy 49 8 ] ] -RRB- cord-027201-owzhv0xy 49 9 or or CC cord-027201-owzhv0xy 49 10 modification modification NN cord-027201-owzhv0xy 49 11 varies vary VBZ cord-027201-owzhv0xy 49 12 depending depend VBG cord-027201-owzhv0xy 49 13 on on IN cord-027201-owzhv0xy 49 14 the the DT cord-027201-owzhv0xy 49 15 chromatin chromatin NN cord-027201-owzhv0xy 49 16 condensation condensation NN cord-027201-owzhv0xy 49 17 level level NN cord-027201-owzhv0xy 49 18 . . . cord-027201-owzhv0xy 50 1 During during IN cord-027201-owzhv0xy 50 2 the the DT cord-027201-owzhv0xy 50 3 cell cell NN cord-027201-owzhv0xy 50 4 division division NN cord-027201-owzhv0xy 50 5 , , , cord-027201-owzhv0xy 50 6 chromatin chromatin NN cord-027201-owzhv0xy 50 7 fibers fiber NNS cord-027201-owzhv0xy 50 8 condense condense VBP cord-027201-owzhv0xy 50 9 into into IN cord-027201-owzhv0xy 50 10 structures structure NNS cord-027201-owzhv0xy 50 11 called call VBN cord-027201-owzhv0xy 50 12 chromosomes chromosome NNS cord-027201-owzhv0xy 50 13 . . . cord-027201-owzhv0xy 51 1 In in IN cord-027201-owzhv0xy 51 2 the the DT cord-027201-owzhv0xy 51 3 period period NN cord-027201-owzhv0xy 51 4 between between IN cord-027201-owzhv0xy 51 5 two two CD cord-027201-owzhv0xy 51 6 subsequent subsequent JJ cord-027201-owzhv0xy 51 7 divisions division NNS cord-027201-owzhv0xy 51 8 , , , cord-027201-owzhv0xy 51 9 called call VBN cord-027201-owzhv0xy 51 10 interphase interphase NN cord-027201-owzhv0xy 51 11 , , , cord-027201-owzhv0xy 51 12 chromosomes chromosome NNS cord-027201-owzhv0xy 51 13 decondense decondense NN cord-027201-owzhv0xy 51 14 and and CC cord-027201-owzhv0xy 51 15 occupy occupy VB cord-027201-owzhv0xy 51 16 3-D 3-d JJ cord-027201-owzhv0xy 51 17 areas area NNS cord-027201-owzhv0xy 51 18 within within IN cord-027201-owzhv0xy 51 19 the the DT cord-027201-owzhv0xy 51 20 nucleus nucleus NN cord-027201-owzhv0xy 51 21 . . . cord-027201-owzhv0xy 52 1 Those those DT cord-027201-owzhv0xy 52 2 distinct distinct JJ cord-027201-owzhv0xy 52 3 areas area NNS cord-027201-owzhv0xy 52 4 -called -called JJ cord-027201-owzhv0xy 52 5 " " '' cord-027201-owzhv0xy 52 6 chromosome chromosome NN cord-027201-owzhv0xy 52 7 territories territory NNS cord-027201-owzhv0xy 52 8 " " '' cord-027201-owzhv0xy 52 9 ( ( -LRB- cord-027201-owzhv0xy 52 10 CT CT NNP cord-027201-owzhv0xy 52 11 's 's POS cord-027201-owzhv0xy 52 12 ) ) -RRB- cord-027201-owzhv0xy 52 13 -are -are : cord-027201-owzhv0xy 52 14 regarded regard VBN cord-027201-owzhv0xy 52 15 as as IN cord-027201-owzhv0xy 52 16 a a DT cord-027201-owzhv0xy 52 17 major major JJ cord-027201-owzhv0xy 52 18 feature feature NN cord-027201-owzhv0xy 52 19 of of IN cord-027201-owzhv0xy 52 20 nuclear nuclear JJ cord-027201-owzhv0xy 52 21 structure structure NN cord-027201-owzhv0xy 52 22 ( ( -LRB- cord-027201-owzhv0xy 52 23 [ [ -LRB- cord-027201-owzhv0xy 52 24 12 12 CD cord-027201-owzhv0xy 52 25 , , , cord-027201-owzhv0xy 52 26 22 22 CD cord-027201-owzhv0xy 52 27 ] ] -RRB- cord-027201-owzhv0xy 52 28 ) ) -RRB- cord-027201-owzhv0xy 52 29 . . . cord-027201-owzhv0xy 53 1 Chromosome chromosome NN cord-027201-owzhv0xy 53 2 territories territory NNS cord-027201-owzhv0xy 53 3 can can MD cord-027201-owzhv0xy 53 4 be be VB cord-027201-owzhv0xy 53 5 visualized visualize VBN cord-027201-owzhv0xy 53 6 directly directly RB cord-027201-owzhv0xy 53 7 using use VBG cord-027201-owzhv0xy 53 8 in in IN cord-027201-owzhv0xy 53 9 - - HYPH cord-027201-owzhv0xy 53 10 situ situ NN cord-027201-owzhv0xy 53 11 hybridization hybridization NN cord-027201-owzhv0xy 53 12 with with IN cord-027201-owzhv0xy 53 13 fluorescently fluorescently RB cord-027201-owzhv0xy 53 14 labeled label VBN cord-027201-owzhv0xy 53 15 DNA dna NN cord-027201-owzhv0xy 53 16 probes probe NNS cord-027201-owzhv0xy 53 17 that that WDT cord-027201-owzhv0xy 53 18 paint paint VBP cord-027201-owzhv0xy 53 19 specifically specifically RB cord-027201-owzhv0xy 53 20 individual individual JJ cord-027201-owzhv0xy 53 21 chromosomes chromosome NNS cord-027201-owzhv0xy 53 22 ( ( -LRB- cord-027201-owzhv0xy 53 23 [ [ -LRB- cord-027201-owzhv0xy 53 24 18 18 CD cord-027201-owzhv0xy 53 25 , , , cord-027201-owzhv0xy 53 26 20 20 CD cord-027201-owzhv0xy 53 27 ] ] -RRB- cord-027201-owzhv0xy 53 28 ) ) -RRB- cord-027201-owzhv0xy 53 29 . . . cord-027201-owzhv0xy 54 1 Researches research NNS cord-027201-owzhv0xy 54 2 concerning concern VBG cord-027201-owzhv0xy 54 3 CT CT NNP cord-027201-owzhv0xy 54 4 's 's POS cord-027201-owzhv0xy 55 1 are be VBP cord-027201-owzhv0xy 55 2 : : : cord-027201-owzhv0xy 55 3 studying study VBG cord-027201-owzhv0xy 55 4 the the DT cord-027201-owzhv0xy 55 5 relationship relationship NN cord-027201-owzhv0xy 55 6 between between IN cord-027201-owzhv0xy 55 7 the the DT cord-027201-owzhv0xy 55 8 internal internal JJ cord-027201-owzhv0xy 55 9 architecture architecture NN cord-027201-owzhv0xy 55 10 of of IN cord-027201-owzhv0xy 55 11 the the DT cord-027201-owzhv0xy 55 12 cell cell NN cord-027201-owzhv0xy 55 13 nucleus nucleus NN cord-027201-owzhv0xy 55 14 and and CC cord-027201-owzhv0xy 55 15 crucial crucial JJ cord-027201-owzhv0xy 55 16 intranuclear intranuclear NN cord-027201-owzhv0xy 55 17 processes process NNS cord-027201-owzhv0xy 55 18 such such JJ cord-027201-owzhv0xy 55 19 as as IN cord-027201-owzhv0xy 55 20 regulation regulation NN cord-027201-owzhv0xy 55 21 of of IN cord-027201-owzhv0xy 55 22 gene gene NN cord-027201-owzhv0xy 55 23 expression expression NN cord-027201-owzhv0xy 55 24 , , , cord-027201-owzhv0xy 55 25 gene gene NN cord-027201-owzhv0xy 55 26 transcription transcription NN cord-027201-owzhv0xy 55 27 or or CC cord-027201-owzhv0xy 55 28 DNA dna NN cord-027201-owzhv0xy 55 29 repair repair NN cord-027201-owzhv0xy 55 30 ( ( -LRB- cord-027201-owzhv0xy 55 31 [ [ -LRB- cord-027201-owzhv0xy 55 32 17 17 CD cord-027201-owzhv0xy 55 33 , , , cord-027201-owzhv0xy 55 34 19 19 CD cord-027201-owzhv0xy 55 35 , , , cord-027201-owzhv0xy 55 36 21 21 CD cord-027201-owzhv0xy 55 37 ] ] -RRB- cord-027201-owzhv0xy 55 38 ) ) -RRB- cord-027201-owzhv0xy 55 39 . . . cord-027201-owzhv0xy 56 1 Those those DT cord-027201-owzhv0xy 56 2 studies study NNS cord-027201-owzhv0xy 56 3 are be VBP cord-027201-owzhv0xy 56 4 related relate VBN cord-027201-owzhv0xy 56 5 to to IN cord-027201-owzhv0xy 56 6 spatial spatial JJ cord-027201-owzhv0xy 56 7 arrangement arrangement NN cord-027201-owzhv0xy 56 8 , , , cord-027201-owzhv0xy 56 9 dynamics dynamic NNS cord-027201-owzhv0xy 56 10 ( ( -LRB- cord-027201-owzhv0xy 56 11 motion motion NN cord-027201-owzhv0xy 56 12 tracking tracking NN cord-027201-owzhv0xy 56 13 ) ) -RRB- cord-027201-owzhv0xy 56 14 [ [ -LRB- cord-027201-owzhv0xy 56 15 13 13 CD cord-027201-owzhv0xy 56 16 ] ] -RRB- cord-027201-owzhv0xy 56 17 , , , cord-027201-owzhv0xy 56 18 frequency frequency NN cord-027201-owzhv0xy 56 19 of of IN cord-027201-owzhv0xy 56 20 genomic genomic JJ cord-027201-owzhv0xy 56 21 translocations translocation NNS cord-027201-owzhv0xy 56 22 ( ( -LRB- cord-027201-owzhv0xy 56 23 [ [ -LRB- cord-027201-owzhv0xy 56 24 14 14 CD cord-027201-owzhv0xy 56 25 ] ] -RRB- cord-027201-owzhv0xy 56 26 ) ) -RRB- cord-027201-owzhv0xy 56 27 and and CC cord-027201-owzhv0xy 56 28 even even RB cord-027201-owzhv0xy 56 29 global global JJ cord-027201-owzhv0xy 56 30 regulation regulation NN cord-027201-owzhv0xy 56 31 of of IN cord-027201-owzhv0xy 56 32 the the DT cord-027201-owzhv0xy 56 33 genome genome NN cord-027201-owzhv0xy 56 34 [ [ -LRB- cord-027201-owzhv0xy 56 35 15 15 CD cord-027201-owzhv0xy 56 36 ] ] -RRB- cord-027201-owzhv0xy 56 37 . . . cord-027201-owzhv0xy 57 1 Possibility possibility NN cord-027201-owzhv0xy 57 2 of of IN cord-027201-owzhv0xy 57 3 making make VBG cord-027201-owzhv0xy 57 4 experiments experiment NNS cord-027201-owzhv0xy 57 5 in in IN cord-027201-owzhv0xy 57 6 - - HYPH cord-027201-owzhv0xy 57 7 silicowould silicowould NN cord-027201-owzhv0xy 57 8 speed speed VB cord-027201-owzhv0xy 57 9 up up RP cord-027201-owzhv0xy 57 10 and and CC cord-027201-owzhv0xy 57 11 make make VB cord-027201-owzhv0xy 57 12 some some DT cord-027201-owzhv0xy 57 13 of of IN cord-027201-owzhv0xy 57 14 the the DT cord-027201-owzhv0xy 57 15 experiments experiment NNS cord-027201-owzhv0xy 57 16 easier easier RBR cord-027201-owzhv0xy 57 17 and and CC cord-027201-owzhv0xy 57 18 cheaper cheap JJR cord-027201-owzhv0xy 57 19 . . . cord-027201-owzhv0xy 58 1 The the DT cord-027201-owzhv0xy 58 2 euchromatin euchromatin NNS cord-027201-owzhv0xy 58 3 was be VBD cord-027201-owzhv0xy 58 4 the the DT cord-027201-owzhv0xy 58 5 starting starting NN cord-027201-owzhv0xy 58 6 point point NN cord-027201-owzhv0xy 58 7 to to IN cord-027201-owzhv0xy 58 8 model model NN cord-027201-owzhv0xy 58 9 chromatin chromatin NN cord-027201-owzhv0xy 58 10 structure structure NN cord-027201-owzhv0xy 58 11 for for IN cord-027201-owzhv0xy 58 12 us -PRON- PRP cord-027201-owzhv0xy 58 13 : : : cord-027201-owzhv0xy 58 14 we -PRON- PRP cord-027201-owzhv0xy 58 15 decided decide VBD cord-027201-owzhv0xy 58 16 to to TO cord-027201-owzhv0xy 58 17 model model VB cord-027201-owzhv0xy 58 18 chromatin chromatin NN cord-027201-owzhv0xy 58 19 ( ( -LRB- cord-027201-owzhv0xy 58 20 and and CC cord-027201-owzhv0xy 58 21 arms arm NNS cord-027201-owzhv0xy 58 22 of of IN cord-027201-owzhv0xy 58 23 chromosomes chromosome NNS cord-027201-owzhv0xy 58 24 ) ) -RRB- cord-027201-owzhv0xy 58 25 as as IN cord-027201-owzhv0xy 58 26 a a DT cord-027201-owzhv0xy 58 27 sequence sequence NN cord-027201-owzhv0xy 58 28 of of IN cord-027201-owzhv0xy 58 29 tangent tangent JJ cord-027201-owzhv0xy 58 30 spheres sphere NNS cord-027201-owzhv0xy 58 31 ( ( -LRB- cord-027201-owzhv0xy 58 32 Fig Fig NNP cord-027201-owzhv0xy 58 33 . . NNP cord-027201-owzhv0xy 58 34 2 2 LS cord-027201-owzhv0xy 58 35 ) ) -RRB- cord-027201-owzhv0xy 58 36 -visually -visually : cord-027201-owzhv0xy 58 37 very very RB cord-027201-owzhv0xy 58 38 similar similar JJ cord-027201-owzhv0xy 58 39 to to IN cord-027201-owzhv0xy 58 40 euchromatin euchromatin VB cord-027201-owzhv0xy 58 41 ( ( -LRB- cord-027201-owzhv0xy 58 42 see see VB cord-027201-owzhv0xy 58 43 Fig Fig NNP cord-027201-owzhv0xy 58 44 . . NNP cord-027201-owzhv0xy 58 45 1 1 CD cord-027201-owzhv0xy 58 46 ) ) -RRB- cord-027201-owzhv0xy 58 47 . . . cord-027201-owzhv0xy 59 1 Because because IN cord-027201-owzhv0xy 59 2 euchromatin euchromatin NNP cord-027201-owzhv0xy 59 3 is be VBZ cord-027201-owzhv0xy 59 4 observed observe VBN cord-027201-owzhv0xy 59 5 as as IN cord-027201-owzhv0xy 59 6 " " `` cord-027201-owzhv0xy 59 7 beads bead NNS cord-027201-owzhv0xy 59 8 on on IN cord-027201-owzhv0xy 59 9 a a DT cord-027201-owzhv0xy 59 10 strand strand NN cord-027201-owzhv0xy 59 11 " " '' cord-027201-owzhv0xy 59 12 and and CC cord-027201-owzhv0xy 59 13 beads bead NNS cord-027201-owzhv0xy 59 14 ( ( -LRB- cord-027201-owzhv0xy 59 15 sometimes sometimes RB cord-027201-owzhv0xy 59 16 also also RB cord-027201-owzhv0xy 59 17 called call VBN cord-027201-owzhv0xy 59 18 " " `` cord-027201-owzhv0xy 59 19 domains domain NNS cord-027201-owzhv0xy 59 20 " " '' cord-027201-owzhv0xy 59 21 ) ) -RRB- cord-027201-owzhv0xy 59 22 are be VBP cord-027201-owzhv0xy 59 23 its -PRON- PRP$ cord-027201-owzhv0xy 59 24 basic basic JJ cord-027201-owzhv0xy 59 25 structural structural JJ cord-027201-owzhv0xy 59 26 units unit NNS cord-027201-owzhv0xy 59 27 , , , cord-027201-owzhv0xy 59 28 we -PRON- PRP cord-027201-owzhv0xy 59 29 decided decide VBD cord-027201-owzhv0xy 59 30 to to TO cord-027201-owzhv0xy 59 31 make make VB cord-027201-owzhv0xy 59 32 a a DT cord-027201-owzhv0xy 59 33 single single JJ cord-027201-owzhv0xy 59 34 sphere sphere NN cord-027201-owzhv0xy 59 35 our -PRON- PRP$ cord-027201-owzhv0xy 59 36 basic basic JJ cord-027201-owzhv0xy 59 37 part part NN cord-027201-owzhv0xy 59 38 of of IN cord-027201-owzhv0xy 59 39 the the DT cord-027201-owzhv0xy 59 40 chromatin chromatin NN cord-027201-owzhv0xy 59 41 chain chain NN cord-027201-owzhv0xy 59 42 component component NN cord-027201-owzhv0xy 59 43 ( ( -LRB- cord-027201-owzhv0xy 59 44 and and CC cord-027201-owzhv0xy 59 45 the the DT cord-027201-owzhv0xy 59 46 basic basic JJ cord-027201-owzhv0xy 59 47 structural structural JJ cord-027201-owzhv0xy 59 48 units unit NNS cord-027201-owzhv0xy 59 49 building build VBG cord-027201-owzhv0xy 59 50 up up RP cord-027201-owzhv0xy 59 51 CTs CTs NNP cord-027201-owzhv0xy 59 52 ) ) -RRB- cord-027201-owzhv0xy 59 53 . . . cord-027201-owzhv0xy 60 1 This this DT cord-027201-owzhv0xy 60 2 allows allow VBZ cord-027201-owzhv0xy 60 3 also also RB cord-027201-owzhv0xy 60 4 to to TO cord-027201-owzhv0xy 60 5 make make VB cord-027201-owzhv0xy 60 6 our -PRON- PRP$ cord-027201-owzhv0xy 60 7 model model NN cord-027201-owzhv0xy 60 8 scalable scalable JJ cord-027201-owzhv0xy 60 9 -by -by : cord-027201-owzhv0xy 60 10 changing change VBG cord-027201-owzhv0xy 60 11 the the DT cord-027201-owzhv0xy 60 12 size size NN cord-027201-owzhv0xy 60 13 of of IN cord-027201-owzhv0xy 60 14 the the DT cord-027201-owzhv0xy 60 15 sphere sphere NN cord-027201-owzhv0xy 60 16 we -PRON- PRP cord-027201-owzhv0xy 60 17 can can MD cord-027201-owzhv0xy 60 18 easily easily RB cord-027201-owzhv0xy 60 19 change change VB cord-027201-owzhv0xy 60 20 the the DT cord-027201-owzhv0xy 60 21 level level NN cord-027201-owzhv0xy 60 22 of of IN cord-027201-owzhv0xy 60 23 chromatin chromatin NN cord-027201-owzhv0xy 60 24 packing packing NN cord-027201-owzhv0xy 60 25 . . . cord-027201-owzhv0xy 61 1 A a DT cord-027201-owzhv0xy 61 2 sphere sphere NN cord-027201-owzhv0xy 61 3 can can MD cord-027201-owzhv0xy 61 4 be be VB cord-027201-owzhv0xy 61 5 also also RB cord-027201-owzhv0xy 61 6 easily easily RB cord-027201-owzhv0xy 61 7 rendered render VBN cord-027201-owzhv0xy 61 8 as as IN cord-027201-owzhv0xy 61 9 graphical graphical JJ cord-027201-owzhv0xy 61 10 primitive primitive NN cord-027201-owzhv0xy 61 11 in in IN cord-027201-owzhv0xy 61 12 most most JJS cord-027201-owzhv0xy 61 13 graphical graphical JJ cord-027201-owzhv0xy 61 14 libraries library NNS cord-027201-owzhv0xy 61 15 which which WDT cord-027201-owzhv0xy 61 16 were be VBD cord-027201-owzhv0xy 61 17 very very RB cord-027201-owzhv0xy 61 18 important important JJ cord-027201-owzhv0xy 61 19 to to TO cord-027201-owzhv0xy 61 20 guarantee guarantee VB cord-027201-owzhv0xy 61 21 the the DT cord-027201-owzhv0xy 61 22 possibility possibility NN cord-027201-owzhv0xy 61 23 of of IN cord-027201-owzhv0xy 61 24 further further JJ cord-027201-owzhv0xy 61 25 CT CT NNP cord-027201-owzhv0xy 61 26 's 's POS cord-027201-owzhv0xy 61 27 visualization visualization NN cord-027201-owzhv0xy 61 28 . . . cord-027201-owzhv0xy 62 1 Our -PRON- PRP$ cord-027201-owzhv0xy 62 2 modeling modeling NN cord-027201-owzhv0xy 62 3 process process NN cord-027201-owzhv0xy 62 4 was be VBD cord-027201-owzhv0xy 62 5 very very RB cord-027201-owzhv0xy 62 6 closely closely RB cord-027201-owzhv0xy 62 7 related related JJ cord-027201-owzhv0xy 62 8 to to IN cord-027201-owzhv0xy 62 9 geometrical geometrical JJ cord-027201-owzhv0xy 62 10 , , , cord-027201-owzhv0xy 62 11 visible visible JJ cord-027201-owzhv0xy 62 12 objects object NNS cord-027201-owzhv0xy 62 13 , , , cord-027201-owzhv0xy 62 14 because because IN cord-027201-owzhv0xy 62 15 it -PRON- PRP cord-027201-owzhv0xy 62 16 was be VBD cord-027201-owzhv0xy 62 17 very very RB cord-027201-owzhv0xy 62 18 important important JJ cord-027201-owzhv0xy 62 19 , , , cord-027201-owzhv0xy 62 20 that that IN cord-027201-owzhv0xy 62 21 the the DT cord-027201-owzhv0xy 62 22 final final JJ cord-027201-owzhv0xy 62 23 models model NNS cord-027201-owzhv0xy 62 24 could could MD cord-027201-owzhv0xy 62 25 be be VB cord-027201-owzhv0xy 62 26 visualized visualize VBN cord-027201-owzhv0xy 62 27 -to -to : cord-027201-owzhv0xy 62 28 allow allow VB cord-027201-owzhv0xy 62 29 visual visual JJ cord-027201-owzhv0xy 62 30 comparison comparison NN cord-027201-owzhv0xy 62 31 with with IN cord-027201-owzhv0xy 62 32 real real JJ cord-027201-owzhv0xy 62 33 images image NNS cord-027201-owzhv0xy 62 34 from from IN cord-027201-owzhv0xy 62 35 confocal confocal JJ cord-027201-owzhv0xy 62 36 microscopy microscopy NNS cord-027201-owzhv0xy 62 37 . . . cord-027201-owzhv0xy 63 1 We -PRON- PRP cord-027201-owzhv0xy 63 2 also also RB cord-027201-owzhv0xy 63 3 decide decide VBP cord-027201-owzhv0xy 63 4 to to TO cord-027201-owzhv0xy 63 5 model model VB cord-027201-owzhv0xy 63 6 the the DT cord-027201-owzhv0xy 63 7 decondensation decondensation NN cord-027201-owzhv0xy 63 8 process process NN cord-027201-owzhv0xy 63 9 by by IN cord-027201-owzhv0xy 63 10 adding add VBG cord-027201-owzhv0xy 63 11 tangent tangent JJ cord-027201-owzhv0xy 63 12 spheres sphere NNS cord-027201-owzhv0xy 63 13 around around IN cord-027201-owzhv0xy 63 14 existing exist VBG cord-027201-owzhv0xy 63 15 ones one NNS cord-027201-owzhv0xy 63 16 . . . cord-027201-owzhv0xy 64 1 This this DT cord-027201-owzhv0xy 64 2 effects effect NNS cord-027201-owzhv0xy 64 3 in in IN cord-027201-owzhv0xy 64 4 gradually gradually RB cord-027201-owzhv0xy 64 5 expanding expand VBG cord-027201-owzhv0xy 64 6 volume volume NN cord-027201-owzhv0xy 64 7 of of IN cord-027201-owzhv0xy 64 8 the the DT cord-027201-owzhv0xy 64 9 initial initial JJ cord-027201-owzhv0xy 64 10 strand strand NN cord-027201-owzhv0xy 64 11 of of IN cord-027201-owzhv0xy 64 12 spheres sphere NNS cord-027201-owzhv0xy 64 13 . . . cord-027201-owzhv0xy 65 1 The the DT cord-027201-owzhv0xy 65 2 process process NN cord-027201-owzhv0xy 65 3 continues continue VBZ cord-027201-owzhv0xy 65 4 until until IN cord-027201-owzhv0xy 65 5 the the DT cord-027201-owzhv0xy 65 6 stop stop NN cord-027201-owzhv0xy 65 7 condition condition NN cord-027201-owzhv0xy 65 8 was be VBD cord-027201-owzhv0xy 65 9 met meet VBN cord-027201-owzhv0xy 65 10 ( ( -LRB- cord-027201-owzhv0xy 65 11 volume volume NN cord-027201-owzhv0xy 65 12 or or CC cord-027201-owzhv0xy 65 13 size size NN cord-027201-owzhv0xy 65 14 of of IN cord-027201-owzhv0xy 65 15 decondensed decondense VBN cord-027201-owzhv0xy 65 16 chromatin chromatin NNP cord-027201-owzhv0xy 65 17 ) ) -RRB- cord-027201-owzhv0xy 65 18 . . . cord-027201-owzhv0xy 66 1 The the DT cord-027201-owzhv0xy 66 2 computational computational JJ cord-027201-owzhv0xy 66 3 problem problem NN cord-027201-owzhv0xy 66 4 was be VBD cord-027201-owzhv0xy 66 5 as as IN cord-027201-owzhv0xy 66 6 follows follow VBZ cord-027201-owzhv0xy 66 7 : : : cord-027201-owzhv0xy 66 8 starting start VBG cord-027201-owzhv0xy 66 9 from from IN cord-027201-owzhv0xy 66 10 the the DT cord-027201-owzhv0xy 66 11 initial initial NN cord-027201-owzhv0xy 66 12 ( ( -LRB- cord-027201-owzhv0xy 66 13 condensed condensed JJ cord-027201-owzhv0xy 66 14 ) ) -RRB- cord-027201-owzhv0xy 66 15 chromatin chromatin NN cord-027201-owzhv0xy 66 16 model model NN cord-027201-owzhv0xy 66 17 ( ( -LRB- cord-027201-owzhv0xy 66 18 in in IN cord-027201-owzhv0xy 66 19 a a DT cord-027201-owzhv0xy 66 20 form form NN cord-027201-owzhv0xy 66 21 " " `` cord-027201-owzhv0xy 66 22 beads bead NNS cord-027201-owzhv0xy 66 23 - - HYPH cord-027201-owzhv0xy 66 24 on on IN cord-027201-owzhv0xy 66 25 - - HYPH cord-027201-owzhv0xy 66 26 strand strand NN cord-027201-owzhv0xy 66 27 " " '' cord-027201-owzhv0xy 66 28 ) ) -RRB- cord-027201-owzhv0xy 66 29 , , , cord-027201-owzhv0xy 66 30 consisting consist VBG cord-027201-owzhv0xy 66 31 of of IN cord-027201-owzhv0xy 66 32 a a DT cord-027201-owzhv0xy 66 33 sequence sequence NN cord-027201-owzhv0xy 66 34 of of IN cord-027201-owzhv0xy 66 35 mutually mutually RB cord-027201-owzhv0xy 66 36 tangent tangent JJ cord-027201-owzhv0xy 66 37 spheres sphere NNS cord-027201-owzhv0xy 66 38 find find VBP cord-027201-owzhv0xy 66 39 coordinates coordinate NNS cord-027201-owzhv0xy 66 40 for for IN cord-027201-owzhv0xy 66 41 next next JJ cord-027201-owzhv0xy 66 42 N n CD cord-027201-owzhv0xy 66 43 spheres sphere NNS cord-027201-owzhv0xy 66 44 ( ( -LRB- cord-027201-owzhv0xy 66 45 where where WRB cord-027201-owzhv0xy 66 46 N N NNP cord-027201-owzhv0xy 66 47 denotes denote VBZ cord-027201-owzhv0xy 66 48 the the DT cord-027201-owzhv0xy 66 49 size size NN cord-027201-owzhv0xy 66 50 -number -number NN cord-027201-owzhv0xy 66 51 of of IN cord-027201-owzhv0xy 66 52 beads bead NNS cord-027201-owzhv0xy 66 53 of of IN cord-027201-owzhv0xy 66 54 chromatin chromatin NN cord-027201-owzhv0xy 66 55 after after IN cord-027201-owzhv0xy 66 56 decondensation decondensation NN cord-027201-owzhv0xy 66 57 ) ) -RRB- cord-027201-owzhv0xy 66 58 . . . cord-027201-owzhv0xy 67 1 Geometrically geometrically RB cord-027201-owzhv0xy 67 2 it -PRON- PRP cord-027201-owzhv0xy 67 3 is be VBZ cord-027201-owzhv0xy 67 4 a a DT cord-027201-owzhv0xy 67 5 problem problem NN cord-027201-owzhv0xy 67 6 of of IN cord-027201-owzhv0xy 67 7 finding finding NN cord-027201-owzhv0xy 67 8 ( ( -LRB- cord-027201-owzhv0xy 67 9 x x SYM cord-027201-owzhv0xy 67 10 , , , cord-027201-owzhv0xy 67 11 y y NNP cord-027201-owzhv0xy 67 12 , , , cord-027201-owzhv0xy 67 13 z z NNP cord-027201-owzhv0xy 67 14 ) ) -RRB- cord-027201-owzhv0xy 67 15 being be VBG cord-027201-owzhv0xy 67 16 the the DT cord-027201-owzhv0xy 67 17 center center NN cord-027201-owzhv0xy 67 18 of of IN cord-027201-owzhv0xy 67 19 a a DT cord-027201-owzhv0xy 67 20 new new JJ cord-027201-owzhv0xy 67 21 sphere sphere NN cord-027201-owzhv0xy 67 22 with with IN cord-027201-owzhv0xy 67 23 the the DT cord-027201-owzhv0xy 67 24 condition condition NN cord-027201-owzhv0xy 67 25 of of IN cord-027201-owzhv0xy 67 26 being be VBG cord-027201-owzhv0xy 67 27 tangent tangent JJ cord-027201-owzhv0xy 67 28 to to IN cord-027201-owzhv0xy 67 29 the the DT cord-027201-owzhv0xy 67 30 previous previous JJ cord-027201-owzhv0xy 67 31 one one NN cord-027201-owzhv0xy 67 32 and and CC cord-027201-owzhv0xy 67 33 not not RB cord-027201-owzhv0xy 67 34 in in IN cord-027201-owzhv0xy 67 35 collision collision NN cord-027201-owzhv0xy 67 36 in in IN cord-027201-owzhv0xy 67 37 any any DT cord-027201-owzhv0xy 67 38 other other JJ cord-027201-owzhv0xy 67 39 ( ( -LRB- cord-027201-owzhv0xy 67 40 previously previously RB cord-027201-owzhv0xy 67 41 generated generate VBN cord-027201-owzhv0xy 67 42 ) ) -RRB- cord-027201-owzhv0xy 67 43 . . . cord-027201-owzhv0xy 68 1 Our -PRON- PRP$ cord-027201-owzhv0xy 68 2 first first JJ cord-027201-owzhv0xy 68 3 goal goal NN cord-027201-owzhv0xy 68 4 was be VBD cord-027201-owzhv0xy 68 5 to to TO cord-027201-owzhv0xy 68 6 make make VB cord-027201-owzhv0xy 68 7 a a DT cord-027201-owzhv0xy 68 8 fully fully RB cord-027201-owzhv0xy 68 9 probabilistic probabilistic JJ cord-027201-owzhv0xy 68 10 model model NN cord-027201-owzhv0xy 68 11 -that -that NN cord-027201-owzhv0xy 68 12 means mean VBZ cord-027201-owzhv0xy 68 13 that that IN cord-027201-owzhv0xy 68 14 we -PRON- PRP cord-027201-owzhv0xy 68 15 do do VBP cord-027201-owzhv0xy 68 16 not not RB cord-027201-owzhv0xy 68 17 add add VB cord-027201-owzhv0xy 68 18 additional additional JJ cord-027201-owzhv0xy 68 19 conditions condition NNS cord-027201-owzhv0xy 68 20 like like IN cord-027201-owzhv0xy 68 21 the the DT cord-027201-owzhv0xy 68 22 position position NN cord-027201-owzhv0xy 68 23 of of IN cord-027201-owzhv0xy 68 24 centromeres centromere NNS cord-027201-owzhv0xy 68 25 , , , cord-027201-owzhv0xy 68 26 telomeres telomere NNS cord-027201-owzhv0xy 68 27 , , , cord-027201-owzhv0xy 68 28 nucleoplasm nucleoplasm JJ cord-027201-owzhv0xy 68 29 stickiness stickiness NN cord-027201-owzhv0xy 68 30 and and CC cord-027201-owzhv0xy 68 31 so so RB cord-027201-owzhv0xy 68 32 on on RB cord-027201-owzhv0xy 68 33 ( ( -LRB- cord-027201-owzhv0xy 68 34 extending extend VBG cord-027201-owzhv0xy 68 35 model model NN cord-027201-owzhv0xy 68 36 and and CC cord-027201-owzhv0xy 68 37 making make VBG cord-027201-owzhv0xy 68 38 it -PRON- PRP cord-027201-owzhv0xy 68 39 more more JJR cord-027201-owzhv0xy 68 40 " " `` cord-027201-owzhv0xy 68 41 real real JJ cord-027201-owzhv0xy 68 42 data data NN cord-027201-owzhv0xy 68 43 - - HYPH cord-027201-owzhv0xy 68 44 driven drive VBN cord-027201-owzhv0xy 68 45 " " '' cord-027201-owzhv0xy 68 46 are be VBP cord-027201-owzhv0xy 68 47 in in IN cord-027201-owzhv0xy 68 48 our -PRON- PRP$ cord-027201-owzhv0xy 68 49 current current JJ cord-027201-owzhv0xy 68 50 field field NN cord-027201-owzhv0xy 68 51 of of IN cord-027201-owzhv0xy 68 52 interest interest NN cord-027201-owzhv0xy 68 53 and and CC cord-027201-owzhv0xy 68 54 research research NN cord-027201-owzhv0xy 68 55 ) ) -RRB- cord-027201-owzhv0xy 68 56 . . . cord-027201-owzhv0xy 69 1 The the DT cord-027201-owzhv0xy 69 2 modeled model VBN cord-027201-owzhv0xy 69 3 process process NN cord-027201-owzhv0xy 69 4 of of IN cord-027201-owzhv0xy 69 5 decondensation decondensation NN cord-027201-owzhv0xy 69 6 can can MD cord-027201-owzhv0xy 69 7 be be VB cord-027201-owzhv0xy 69 8 somehow somehow RB cord-027201-owzhv0xy 69 9 regarded regard VBN cord-027201-owzhv0xy 69 10 as as IN cord-027201-owzhv0xy 69 11 a a DT cord-027201-owzhv0xy 69 12 Markov Markov NNP cord-027201-owzhv0xy 69 13 process process NN cord-027201-owzhv0xy 69 14 -the -the DT cord-027201-owzhv0xy 69 15 subsequent subsequent JJ cord-027201-owzhv0xy 69 16 state state NN cord-027201-owzhv0xy 70 1 i i PRP cord-027201-owzhv0xy 70 2 + + CC cord-027201-owzhv0xy 71 1 1 1 CD cord-027201-owzhv0xy 71 2 of of IN cord-027201-owzhv0xy 71 3 decondensation decondensation NN cord-027201-owzhv0xy 71 4 strictly strictly RB cord-027201-owzhv0xy 71 5 depends depend VBZ cord-027201-owzhv0xy 71 6 on on IN cord-027201-owzhv0xy 71 7 the the DT cord-027201-owzhv0xy 71 8 previous previous JJ cord-027201-owzhv0xy 71 9 one one CD cord-027201-owzhv0xy 71 10 i. i. NN cord-027201-owzhv0xy 72 1 The the DT cord-027201-owzhv0xy 72 2 very very RB cord-027201-owzhv0xy 72 3 basic basic JJ cord-027201-owzhv0xy 72 4 component component NN cord-027201-owzhv0xy 72 5 of of IN cord-027201-owzhv0xy 72 6 our -PRON- PRP$ cord-027201-owzhv0xy 72 7 model model NN cord-027201-owzhv0xy 72 8 was be VBD cord-027201-owzhv0xy 72 9 a a DT cord-027201-owzhv0xy 72 10 sphere sphere NN cord-027201-owzhv0xy 72 11 S((x S((x NNP cord-027201-owzhv0xy 72 12 , , , cord-027201-owzhv0xy 72 13 y y NNP cord-027201-owzhv0xy 72 14 , , , cord-027201-owzhv0xy 72 15 z z NNP cord-027201-owzhv0xy 72 16 ) ) -RRB- cord-027201-owzhv0xy 73 1 , , , cord-027201-owzhv0xy 73 2 r r LS cord-027201-owzhv0xy 73 3 ) ) -RRB- cord-027201-owzhv0xy 73 4 . . . cord-027201-owzhv0xy 74 1 This this DT cord-027201-owzhv0xy 74 2 notation notation NN cord-027201-owzhv0xy 74 3 should should MD cord-027201-owzhv0xy 74 4 be be VB cord-027201-owzhv0xy 74 5 read read VBN cord-027201-owzhv0xy 74 6 as as IN cord-027201-owzhv0xy 74 7 a a DT cord-027201-owzhv0xy 74 8 sphere sphere NN cord-027201-owzhv0xy 74 9 S s NN cord-027201-owzhv0xy 74 10 with with IN cord-027201-owzhv0xy 74 11 a a DT cord-027201-owzhv0xy 74 12 center center NN cord-027201-owzhv0xy 74 13 in in IN cord-027201-owzhv0xy 74 14 the the DT cord-027201-owzhv0xy 74 15 point point NN cord-027201-owzhv0xy 74 16 that that WDT cord-027201-owzhv0xy 74 17 has have VBZ cord-027201-owzhv0xy 74 18 ( ( -LRB- cord-027201-owzhv0xy 74 19 x x SYM cord-027201-owzhv0xy 74 20 , , , cord-027201-owzhv0xy 74 21 y y NNP cord-027201-owzhv0xy 74 22 , , , cord-027201-owzhv0xy 74 23 z z NNP cord-027201-owzhv0xy 74 24 ) ) -RRB- cord-027201-owzhv0xy 74 25 coordinates coordinate VBZ cord-027201-owzhv0xy 74 26 and and CC cord-027201-owzhv0xy 74 27 a a DT cord-027201-owzhv0xy 74 28 radius radius NN cord-027201-owzhv0xy 74 29 with with IN cord-027201-owzhv0xy 74 30 the the DT cord-027201-owzhv0xy 74 31 length length NN cord-027201-owzhv0xy 74 32 of of IN cord-027201-owzhv0xy 74 33 r r NN cord-027201-owzhv0xy 74 34 , , , cord-027201-owzhv0xy 74 35 ( ( -LRB- cord-027201-owzhv0xy 74 36 r r NN cord-027201-owzhv0xy 74 37 ≥ ≥ CD cord-027201-owzhv0xy 74 38 0 0 CD cord-027201-owzhv0xy 74 39 ) ) -RRB- cord-027201-owzhv0xy 74 40 . . . cord-027201-owzhv0xy 75 1 The the DT cord-027201-owzhv0xy 75 2 ordered order VBN cord-027201-owzhv0xy 75 3 chain chain NN cord-027201-owzhv0xy 75 4 of of IN cord-027201-owzhv0xy 75 5 spheres sphere NNS cord-027201-owzhv0xy 75 6 -makes -make VBZ cord-027201-owzhv0xy 75 7 our -PRON- PRP$ cord-027201-owzhv0xy 75 8 model model NN cord-027201-owzhv0xy 75 9 of of IN cord-027201-owzhv0xy 75 10 a a DT cord-027201-owzhv0xy 75 11 chromosome chromosome NN cord-027201-owzhv0xy 75 12 , , , cord-027201-owzhv0xy 75 13 a a DT cord-027201-owzhv0xy 75 14 set set NN cord-027201-owzhv0xy 75 15 of of IN cord-027201-owzhv0xy 75 16 indexed index VBN cord-027201-owzhv0xy 75 17 spheres sphere NNS cord-027201-owzhv0xy 75 18 makes make VBZ cord-027201-owzhv0xy 75 19 a a DT cord-027201-owzhv0xy 75 20 model model NN cord-027201-owzhv0xy 75 21 of of IN cord-027201-owzhv0xy 75 22 CT CT NNP cord-027201-owzhv0xy 75 23 . . . cord-027201-owzhv0xy 76 1 The the DT cord-027201-owzhv0xy 76 2 very very RB cord-027201-owzhv0xy 76 3 general general JJ cord-027201-owzhv0xy 76 4 algorithm algorithm NN cord-027201-owzhv0xy 76 5 for for IN cord-027201-owzhv0xy 76 6 CT CT NNP cord-027201-owzhv0xy 76 7 's 's POS cord-027201-owzhv0xy 76 8 modeling modeling NN cord-027201-owzhv0xy 76 9 is be VBZ cord-027201-owzhv0xy 76 10 presented present VBN cord-027201-owzhv0xy 76 11 in in IN cord-027201-owzhv0xy 76 12 Algorithm Algorithm NNP cord-027201-owzhv0xy 76 13 1 1 CD cord-027201-owzhv0xy 76 14 . . . cord-027201-owzhv0xy 77 1 Line Line NNP cord-027201-owzhv0xy 77 2 4 4 CD cord-027201-owzhv0xy 77 3 and and CC cord-027201-owzhv0xy 77 4 5 5 CD cord-027201-owzhv0xy 77 5 reflect reflect VBP cord-027201-owzhv0xy 77 6 creating create VBG cord-027201-owzhv0xy 77 7 initial initial JJ cord-027201-owzhv0xy 77 8 chromatin chromatin NN cord-027201-owzhv0xy 77 9 strand strand NN cord-027201-owzhv0xy 77 10 , , , cord-027201-owzhv0xy 77 11 line line NN cord-027201-owzhv0xy 77 12 6 6 CD cord-027201-owzhv0xy 77 13 simulation simulation NN cord-027201-owzhv0xy 77 14 of of IN cord-027201-owzhv0xy 77 15 decondensation decondensation NN cord-027201-owzhv0xy 77 16 . . . cord-027201-owzhv0xy 78 1 Altogether altogether RB cord-027201-owzhv0xy 78 2 , , , cord-027201-owzhv0xy 78 3 they -PRON- PRP cord-027201-owzhv0xy 78 4 led lead VBD cord-027201-owzhv0xy 78 5 to to IN cord-027201-owzhv0xy 78 6 the the DT cord-027201-owzhv0xy 78 7 generation generation NN cord-027201-owzhv0xy 78 8 of of IN cord-027201-owzhv0xy 78 9 the the DT cord-027201-owzhv0xy 78 10 model model NN cord-027201-owzhv0xy 78 11 of of IN cord-027201-owzhv0xy 78 12 the the DT cord-027201-owzhv0xy 78 13 certain certain JJ cord-027201-owzhv0xy 78 14 CT CT NNP cord-027201-owzhv0xy 78 15 . . . cord-027201-owzhv0xy 79 1 The the DT cord-027201-owzhv0xy 79 2 last last JJ cord-027201-owzhv0xy 79 3 step step NN cord-027201-owzhv0xy 79 4 of of IN cord-027201-owzhv0xy 79 5 the the DT cord-027201-owzhv0xy 79 6 algorithm algorithm NN cord-027201-owzhv0xy 79 7 ( ( -LRB- cord-027201-owzhv0xy 79 8 line line NN cord-027201-owzhv0xy 79 9 6 6 CD cord-027201-owzhv0xy 79 10 ) ) -RRB- cord-027201-owzhv0xy 79 11 proved prove VBD cord-027201-owzhv0xy 79 12 to to TO cord-027201-owzhv0xy 79 13 be be VB cord-027201-owzhv0xy 79 14 the the DT cord-027201-owzhv0xy 79 15 most most RBS cord-027201-owzhv0xy 79 16 demanding demanding JJ cord-027201-owzhv0xy 79 17 and and CC cord-027201-owzhv0xy 79 18 challenging challenging JJ cord-027201-owzhv0xy 79 19 , , , cord-027201-owzhv0xy 79 20 which which WDT cord-027201-owzhv0xy 79 21 is be VBZ cord-027201-owzhv0xy 79 22 described describe VBN cord-027201-owzhv0xy 79 23 in in IN cord-027201-owzhv0xy 79 24 the the DT cord-027201-owzhv0xy 79 25 next next JJ cord-027201-owzhv0xy 79 26 section section NN cord-027201-owzhv0xy 79 27 . . . cord-027201-owzhv0xy 80 1 In in IN cord-027201-owzhv0xy 80 2 the the DT cord-027201-owzhv0xy 80 3 following following JJ cord-027201-owzhv0xy 80 4 section section NN cord-027201-owzhv0xy 80 5 , , , cord-027201-owzhv0xy 80 6 we -PRON- PRP cord-027201-owzhv0xy 80 7 document document VBP cord-027201-owzhv0xy 80 8 the the DT cord-027201-owzhv0xy 80 9 way way NN cord-027201-owzhv0xy 80 10 we -PRON- PRP cord-027201-owzhv0xy 80 11 take take VBP cord-027201-owzhv0xy 80 12 to to TO cord-027201-owzhv0xy 80 13 successfully successfully RB cord-027201-owzhv0xy 80 14 made make VBN cord-027201-owzhv0xy 80 15 the the DT cord-027201-owzhv0xy 80 16 probabilistic probabilistic JJ cord-027201-owzhv0xy 80 17 model model NN cord-027201-owzhv0xy 80 18 of of IN cord-027201-owzhv0xy 80 19 CT CT NNP cord-027201-owzhv0xy 80 20 's 's POS cord-027201-owzhv0xy 80 21 . . . cord-027201-owzhv0xy 81 1 At at IN cord-027201-owzhv0xy 81 2 first first RB cord-027201-owzhv0xy 81 3 , , , cord-027201-owzhv0xy 81 4 we -PRON- PRP cord-027201-owzhv0xy 81 5 used use VBD cord-027201-owzhv0xy 81 6 the the DT cord-027201-owzhv0xy 81 7 Cartesian Cartesian NNP cord-027201-owzhv0xy 81 8 coordinates coordinate NNS cord-027201-owzhv0xy 81 9 ( ( -LRB- cord-027201-owzhv0xy 81 10 CC CC NNP cord-027201-owzhv0xy 81 11 ) ) -RRB- cord-027201-owzhv0xy 81 12 . . . cord-027201-owzhv0xy 82 1 First first RB cord-027201-owzhv0xy 82 2 , , , cord-027201-owzhv0xy 82 3 the the DT cord-027201-owzhv0xy 82 4 algorithm algorithm NN cord-027201-owzhv0xy 82 5 generates generate VBZ cord-027201-owzhv0xy 82 6 coordinates coordinate NNS cord-027201-owzhv0xy 82 7 for for IN cord-027201-owzhv0xy 82 8 the the DT cord-027201-owzhv0xy 82 9 sphere sphere NN cord-027201-owzhv0xy 82 10 that that WDT cord-027201-owzhv0xy 82 11 are be VBP cord-027201-owzhv0xy 82 12 denoted denote VBN cord-027201-owzhv0xy 82 13 as as IN cord-027201-owzhv0xy 82 14 the the DT cord-027201-owzhv0xy 82 15 centromere centromere NN cord-027201-owzhv0xy 82 16 , , , cord-027201-owzhv0xy 82 17 and and CC cord-027201-owzhv0xy 82 18 next next JJ cord-027201-owzhv0xy 82 19 add add NN cord-027201-owzhv0xy 82 20 to to IN cord-027201-owzhv0xy 82 21 it -PRON- PRP cord-027201-owzhv0xy 82 22 the the DT cord-027201-owzhv0xy 82 23 next next JJ cord-027201-owzhv0xy 82 24 ones one NNS cord-027201-owzhv0xy 82 25 until until IN cord-027201-owzhv0xy 82 26 it -PRON- PRP cord-027201-owzhv0xy 82 27 reaches reach VBZ cord-027201-owzhv0xy 82 28 the the DT cord-027201-owzhv0xy 82 29 ( ( -LRB- cord-027201-owzhv0xy 82 30 given give VBN cord-027201-owzhv0xy 82 31 a a DT cord-027201-owzhv0xy 82 32 - - HYPH cord-027201-owzhv0xy 82 33 priori priori FW cord-027201-owzhv0xy 82 34 ) ) -RRB- cord-027201-owzhv0xy 82 35 length length NN cord-027201-owzhv0xy 82 36 of of IN cord-027201-owzhv0xy 82 37 arms arm NNS cord-027201-owzhv0xy 82 38 for for IN cord-027201-owzhv0xy 82 39 certain certain JJ cord-027201-owzhv0xy 82 40 chromosome chromosome NN cord-027201-owzhv0xy 82 41 . . . cord-027201-owzhv0xy 83 1 Having have VBG cord-027201-owzhv0xy 83 2 model model NN cord-027201-owzhv0xy 83 3 of of IN cord-027201-owzhv0xy 83 4 the the DT cord-027201-owzhv0xy 83 5 entire entire JJ cord-027201-owzhv0xy 83 6 chromosome chromosome NN cord-027201-owzhv0xy 83 7 algorithm algorithm NN cord-027201-owzhv0xy 83 8 draw draw VBP cord-027201-owzhv0xy 83 9 a a DT cord-027201-owzhv0xy 83 10 i -PRON- PRP cord-027201-owzhv0xy 83 11 d d NN cord-027201-owzhv0xy 83 12 of of IN cord-027201-owzhv0xy 83 13 one one CD cord-027201-owzhv0xy 83 14 of of IN cord-027201-owzhv0xy 83 15 the the DT cord-027201-owzhv0xy 83 16 present present JJ cord-027201-owzhv0xy 83 17 spheres sphere NNS cord-027201-owzhv0xy 84 1 S S NNP cord-027201-owzhv0xy 84 2 i i CD cord-027201-owzhv0xy 85 1 ( ( -LRB- cord-027201-owzhv0xy 86 1 ( ( -LRB- cord-027201-owzhv0xy 86 2 x x NNP cord-027201-owzhv0xy 86 3 i i NNP cord-027201-owzhv0xy 86 4 , , , cord-027201-owzhv0xy 86 5 y y NNP cord-027201-owzhv0xy 86 6 i i NNP cord-027201-owzhv0xy 86 7 , , , cord-027201-owzhv0xy 86 8 z z NNP cord-027201-owzhv0xy 86 9 i i NNP cord-027201-owzhv0xy 86 10 ) ) -RRB- cord-027201-owzhv0xy 86 11 , , , cord-027201-owzhv0xy 86 12 r r LS cord-027201-owzhv0xy 86 13 ) ) -RRB- cord-027201-owzhv0xy 86 14 ( ( -LRB- cord-027201-owzhv0xy 86 15 from from IN cord-027201-owzhv0xy 86 16 those those DT cord-027201-owzhv0xy 86 17 composed compose VBN cord-027201-owzhv0xy 86 18 the the DT cord-027201-owzhv0xy 86 19 chromosome chromosome NN cord-027201-owzhv0xy 86 20 ) ) -RRB- cord-027201-owzhv0xy 86 21 and and CC cord-027201-owzhv0xy 86 22 then then RB cord-027201-owzhv0xy 86 23 draws draw VBZ cord-027201-owzhv0xy 86 24 " " `` cord-027201-owzhv0xy 86 25 candidate candidate NN cord-027201-owzhv0xy 86 26 coordinates coordinate VBZ cord-027201-owzhv0xy 86 27 " " '' cord-027201-owzhv0xy 86 28 : : : cord-027201-owzhv0xy 87 1 x x LS cord-027201-owzhv0xy 87 2 i+1 i+1 NN cord-027201-owzhv0xy 87 3 , , , cord-027201-owzhv0xy 87 4 y y NNP cord-027201-owzhv0xy 87 5 i+1 i+1 NN cord-027201-owzhv0xy 87 6 and and CC cord-027201-owzhv0xy 87 7 z z NNP cord-027201-owzhv0xy 87 8 i+1 i+1 NN cord-027201-owzhv0xy 87 9 for for IN cord-027201-owzhv0xy 87 10 the the DT cord-027201-owzhv0xy 87 11 center center NN cord-027201-owzhv0xy 87 12 for for IN cord-027201-owzhv0xy 87 13 the the DT cord-027201-owzhv0xy 87 14 next next JJ cord-027201-owzhv0xy 87 15 sphere sphere NN cord-027201-owzhv0xy 87 16 . . . cord-027201-owzhv0xy 88 1 The the DT cord-027201-owzhv0xy 88 2 new new JJ cord-027201-owzhv0xy 88 3 coordinates coordinate NNS cord-027201-owzhv0xy 88 4 are be VBP cord-027201-owzhv0xy 88 5 to to TO cord-027201-owzhv0xy 88 6 be be VB cord-027201-owzhv0xy 88 7 from from IN cord-027201-owzhv0xy 88 8 limited limited JJ cord-027201-owzhv0xy 88 9 range range NN cord-027201-owzhv0xy 88 10 -not -not : cord-027201-owzhv0xy 88 11 too too RB cord-027201-owzhv0xy 88 12 far far RB cord-027201-owzhv0xy 88 13 current current JJ cord-027201-owzhv0xy 88 14 sphere sphere NN cord-027201-owzhv0xy 88 15 's 's POS cord-027201-owzhv0xy 88 16 ( ( -LRB- cord-027201-owzhv0xy 88 17 as as IN cord-027201-owzhv0xy 88 18 they -PRON- PRP cord-027201-owzhv0xy 88 19 should should MD cord-027201-owzhv0xy 88 20 be be VB cord-027201-owzhv0xy 88 21 tangent tangent JJ cord-027201-owzhv0xy 88 22 ) ) -RRB- cord-027201-owzhv0xy 88 23 . . . cord-027201-owzhv0xy 89 1 To to TO cord-027201-owzhv0xy 89 2 allow allow VB cord-027201-owzhv0xy 89 3 small small JJ cord-027201-owzhv0xy 89 4 flexibility flexibility NN cord-027201-owzhv0xy 89 5 , , , cord-027201-owzhv0xy 89 6 the the DT cord-027201-owzhv0xy 89 7 ε ε NNP cord-027201-owzhv0xy 89 8 value value NN cord-027201-owzhv0xy 89 9 to to IN cord-027201-owzhv0xy 89 10 the the DT cord-027201-owzhv0xy 89 11 drawn draw VBN cord-027201-owzhv0xy 89 12 coordinates coordinate NNS cord-027201-owzhv0xy 89 13 was be VBD cord-027201-owzhv0xy 89 14 introduced introduce VBN cord-027201-owzhv0xy 89 15 . . . cord-027201-owzhv0xy 90 1 When when WRB cord-027201-owzhv0xy 90 2 we -PRON- PRP cord-027201-owzhv0xy 90 3 had have VBD cord-027201-owzhv0xy 90 4 coordinates coordinate NNS cord-027201-owzhv0xy 90 5 drawn draw VBN cord-027201-owzhv0xy 90 6 , , , cord-027201-owzhv0xy 90 7 the the DT cord-027201-owzhv0xy 90 8 distance distance NN cord-027201-owzhv0xy 90 9 dist(S dist( NNS cord-027201-owzhv0xy 91 1 i i PRP cord-027201-owzhv0xy 91 2 , , , cord-027201-owzhv0xy 91 3 S S NNP cord-027201-owzhv0xy 91 4 i+1 i+1 NN cord-027201-owzhv0xy 91 5 ) ) -RRB- cord-027201-owzhv0xy 91 6 was be VBD cord-027201-owzhv0xy 91 7 calculated calculate VBN cord-027201-owzhv0xy 91 8 to to TO cord-027201-owzhv0xy 91 9 check check VB cord-027201-owzhv0xy 91 10 whether whether IN cord-027201-owzhv0xy 91 11 a a DT cord-027201-owzhv0xy 91 12 new new JJ cord-027201-owzhv0xy 91 13 sphere sphere NN cord-027201-owzhv0xy 91 14 can can MD cord-027201-owzhv0xy 91 15 be be VB cord-027201-owzhv0xy 91 16 added add VBN cord-027201-owzhv0xy 91 17 . . . cord-027201-owzhv0xy 92 1 The the DT cord-027201-owzhv0xy 92 2 distance distance NN cord-027201-owzhv0xy 92 3 was be VBD cord-027201-owzhv0xy 92 4 computed compute VBN cord-027201-owzhv0xy 92 5 by by IN cord-027201-owzhv0xy 92 6 calculating calculate VBG cord-027201-owzhv0xy 92 7 ordinary ordinary JJ cord-027201-owzhv0xy 92 8 Euclidean euclidean JJ cord-027201-owzhv0xy 92 9 distance distance NN cord-027201-owzhv0xy 92 10 . . . cord-027201-owzhv0xy 93 1 If if IN cord-027201-owzhv0xy 93 2 dist(S dist( NNS cord-027201-owzhv0xy 94 1 i i PRP cord-027201-owzhv0xy 94 2 , , , cord-027201-owzhv0xy 94 3 S S NNP cord-027201-owzhv0xy 94 4 i+1 i+1 NN cord-027201-owzhv0xy 94 5 ) ) -RRB- cord-027201-owzhv0xy 94 6 was be VBD cord-027201-owzhv0xy 94 7 appropriate appropriate JJ cord-027201-owzhv0xy 94 8 , , , cord-027201-owzhv0xy 94 9 the the DT cord-027201-owzhv0xy 94 10 conditions condition NNS cord-027201-owzhv0xy 94 11 to to TO cord-027201-owzhv0xy 94 12 not not RB cord-027201-owzhv0xy 94 13 collide collide VB cord-027201-owzhv0xy 94 14 with with IN cord-027201-owzhv0xy 94 15 existing existing JJ cord-027201-owzhv0xy 94 16 elements element NNS cord-027201-owzhv0xy 94 17 were be VBD cord-027201-owzhv0xy 94 18 checked check VBN cord-027201-owzhv0xy 94 19 . . . cord-027201-owzhv0xy 95 1 If if IN cord-027201-owzhv0xy 95 2 all all DT cord-027201-owzhv0xy 95 3 conditions condition NNS cord-027201-owzhv0xy 95 4 are be VBP cord-027201-owzhv0xy 95 5 met meet VBN cord-027201-owzhv0xy 95 6 -new -new : cord-027201-owzhv0xy 95 7 sphere sphere NN cord-027201-owzhv0xy 95 8 were be VBD cord-027201-owzhv0xy 95 9 added add VBN cord-027201-owzhv0xy 95 10 ( ( -LRB- cord-027201-owzhv0xy 95 11 for for IN cord-027201-owzhv0xy 95 12 details detail NNS cord-027201-owzhv0xy 95 13 see see VBP cord-027201-owzhv0xy 95 14 [ [ -LRB- cord-027201-owzhv0xy 95 15 26 26 CD cord-027201-owzhv0xy 95 16 ] ] -RRB- cord-027201-owzhv0xy 95 17 ) ) -RRB- cord-027201-owzhv0xy 95 18 . . . cord-027201-owzhv0xy 96 1 There there EX cord-027201-owzhv0xy 96 2 were be VBD cord-027201-owzhv0xy 96 3 no no DT cord-027201-owzhv0xy 96 4 problems problem NNS cord-027201-owzhv0xy 96 5 with with IN cord-027201-owzhv0xy 96 6 the the DT cord-027201-owzhv0xy 96 7 generation generation NN cord-027201-owzhv0xy 96 8 of of IN cord-027201-owzhv0xy 96 9 the the DT cord-027201-owzhv0xy 96 10 initial initial JJ cord-027201-owzhv0xy 96 11 chromatin chromatin NN cord-027201-owzhv0xy 96 12 strand strand NN cord-027201-owzhv0xy 96 13 as as IN cord-027201-owzhv0xy 96 14 a a DT cord-027201-owzhv0xy 96 15 sequence sequence NN cord-027201-owzhv0xy 96 16 of of IN cord-027201-owzhv0xy 96 17 spheres sphere NNS cord-027201-owzhv0xy 96 18 ( ( -LRB- cord-027201-owzhv0xy 96 19 chromosome chromosome NN cord-027201-owzhv0xy 96 20 ) ) -RRB- cord-027201-owzhv0xy 96 21 . . . cord-027201-owzhv0xy 97 1 The the DT cord-027201-owzhv0xy 97 2 problem problem NN cord-027201-owzhv0xy 97 3 emerges emerge VBZ cord-027201-owzhv0xy 97 4 when when WRB cord-027201-owzhv0xy 97 5 we -PRON- PRP cord-027201-owzhv0xy 97 6 tried try VBD cord-027201-owzhv0xy 97 7 to to TO cord-027201-owzhv0xy 97 8 simulate simulate VB cord-027201-owzhv0xy 97 9 the the DT cord-027201-owzhv0xy 97 10 decondensation decondensation NN cord-027201-owzhv0xy 97 11 of of IN cord-027201-owzhv0xy 97 12 chromatin chromatin NN cord-027201-owzhv0xy 97 13 : : : cord-027201-owzhv0xy 97 14 generation generation NN cord-027201-owzhv0xy 97 15 of of IN cord-027201-owzhv0xy 97 16 a a DT cord-027201-owzhv0xy 97 17 model model NN cord-027201-owzhv0xy 97 18 takes take VBZ cord-027201-owzhv0xy 97 19 a a DT cord-027201-owzhv0xy 97 20 lot lot NN cord-027201-owzhv0xy 97 21 of of IN cord-027201-owzhv0xy 97 22 time time NN cord-027201-owzhv0xy 97 23 , , , cord-027201-owzhv0xy 97 24 and and CC cord-027201-owzhv0xy 97 25 we -PRON- PRP cord-027201-owzhv0xy 97 26 noticed notice VBD cord-027201-owzhv0xy 97 27 that that IN cord-027201-owzhv0xy 97 28 sometimes sometimes RB cord-027201-owzhv0xy 97 29 simulation simulation NN cord-027201-owzhv0xy 97 30 was be VBD cord-027201-owzhv0xy 97 31 unsuccessful unsuccessful JJ cord-027201-owzhv0xy 97 32 . . . cord-027201-owzhv0xy 98 1 We -PRON- PRP cord-027201-owzhv0xy 98 2 discovered discover VBD cord-027201-owzhv0xy 98 3 ( ( -LRB- cord-027201-owzhv0xy 98 4 after after IN cord-027201-owzhv0xy 98 5 log log NN cord-027201-owzhv0xy 98 6 analysis analysis NN cord-027201-owzhv0xy 98 7 ) ) -RRB- cord-027201-owzhv0xy 98 8 that that IN cord-027201-owzhv0xy 98 9 the the DT cord-027201-owzhv0xy 98 10 algorithm algorithm NN cord-027201-owzhv0xy 98 11 got get VBD cord-027201-owzhv0xy 98 12 stuck stick VBN cord-027201-owzhv0xy 98 13 trying try VBG cord-027201-owzhv0xy 98 14 to to TO cord-027201-owzhv0xy 98 15 find find VB cord-027201-owzhv0xy 98 16 coordinates coordinate NNS cord-027201-owzhv0xy 98 17 for for IN cord-027201-owzhv0xy 98 18 S S NNP cord-027201-owzhv0xy 98 19 i+1 i+1 NN cord-027201-owzhv0xy 98 20 . . . cord-027201-owzhv0xy 99 1 So so RB cord-027201-owzhv0xy 99 2 , , , cord-027201-owzhv0xy 99 3 we -PRON- PRP cord-027201-owzhv0xy 99 4 added add VBD cord-027201-owzhv0xy 99 5 additional additional JJ cord-027201-owzhv0xy 99 6 function function NN cord-027201-owzhv0xy 99 7 that that WDT cord-027201-owzhv0xy 99 8 triggers trigger VBZ cord-027201-owzhv0xy 99 9 restart restart NN cord-027201-owzhv0xy 99 10 of of IN cord-027201-owzhv0xy 99 11 algorithm algorithm NN cord-027201-owzhv0xy 99 12 after after IN cord-027201-owzhv0xy 99 13 500 500 CD cord-027201-owzhv0xy 99 14 unsuccessful unsuccessful JJ cord-027201-owzhv0xy 99 15 attempts attempt NNS cord-027201-owzhv0xy 99 16 for for IN cord-027201-owzhv0xy 99 17 placing place VBG cord-027201-owzhv0xy 99 18 S S NNP cord-027201-owzhv0xy 99 19 i+1 i+1 NN cord-027201-owzhv0xy 99 20 sphere sphere NN cord-027201-owzhv0xy 99 21 ( ( -LRB- cord-027201-owzhv0xy 99 22 see see VB cord-027201-owzhv0xy 99 23 Algorithm algorithm NN cord-027201-owzhv0xy 99 24 2 2 CD cord-027201-owzhv0xy 99 25 lines line NNS cord-027201-owzhv0xy 99 26 12 12 CD cord-027201-owzhv0xy 99 27 - - SYM cord-027201-owzhv0xy 99 28 14 14 CD cord-027201-owzhv0xy 99 29 ) ) -RRB- cord-027201-owzhv0xy 99 30 . . . cord-027201-owzhv0xy 100 1 If if IN cord-027201-owzhv0xy 100 2 S s NN cord-027201-owzhv0xy 100 3 i+1 i+1 NN cord-027201-owzhv0xy 100 4 can can MD cord-027201-owzhv0xy 100 5 not not RB cord-027201-owzhv0xy 100 6 be be VB cord-027201-owzhv0xy 100 7 placed place VBN cord-027201-owzhv0xy 100 8 -algorithm -algorithm : cord-027201-owzhv0xy 100 9 starts start NNS cord-027201-owzhv0xy 100 10 over over RB cord-027201-owzhv0xy 100 11 and and CC cord-027201-owzhv0xy 100 12 searches search VBZ cord-027201-owzhv0xy 100 13 possibility possibility NN cord-027201-owzhv0xy 100 14 to to TO cord-027201-owzhv0xy 100 15 add add VB cord-027201-owzhv0xy 100 16 S S NNP cord-027201-owzhv0xy 100 17 i+1 i+1 NN cord-027201-owzhv0xy 100 18 , , , cord-027201-owzhv0xy 100 19 but but CC cord-027201-owzhv0xy 100 20 for for IN cord-027201-owzhv0xy 100 21 another another DT cord-027201-owzhv0xy 100 22 sphere sphere JJ cord-027201-owzhv0xy 100 23 forming form VBG cord-027201-owzhv0xy 100 24 chromosome chromosome NN cord-027201-owzhv0xy 100 25 . . . cord-027201-owzhv0xy 101 1 The the DT cord-027201-owzhv0xy 101 2 pseudocode pseudocode NN cord-027201-owzhv0xy 101 3 for for IN cord-027201-owzhv0xy 101 4 this this DT cord-027201-owzhv0xy 101 5 version version NN cord-027201-owzhv0xy 101 6 of of IN cord-027201-owzhv0xy 101 7 the the DT cord-027201-owzhv0xy 101 8 algorithm algorithm NN cord-027201-owzhv0xy 101 9 is be VBZ cord-027201-owzhv0xy 101 10 shown show VBN cord-027201-owzhv0xy 101 11 in in IN cord-027201-owzhv0xy 101 12 Algorithm Algorithm NNP cord-027201-owzhv0xy 101 13 2 2 CD cord-027201-owzhv0xy 101 14 . . . cord-027201-owzhv0xy 102 1 In in IN cord-027201-owzhv0xy 102 2 the the DT cord-027201-owzhv0xy 102 3 first first JJ cord-027201-owzhv0xy 102 4 step step NN cord-027201-owzhv0xy 102 5 it -PRON- PRP cord-027201-owzhv0xy 102 6 generates generate VBZ cord-027201-owzhv0xy 102 7 the the DT cord-027201-owzhv0xy 102 8 " " `` cord-027201-owzhv0xy 102 9 candidate candidate NN cord-027201-owzhv0xy 102 10 coordinates coordinate VBZ cord-027201-owzhv0xy 102 11 " " '' cord-027201-owzhv0xy 102 12 for for IN cord-027201-owzhv0xy 102 13 S S NNP cord-027201-owzhv0xy 102 14 i+1 i+1 NN cord-027201-owzhv0xy 102 15 center center NN cord-027201-owzhv0xy 103 1 ( ( -LRB- cord-027201-owzhv0xy 103 2 Algorithm algorithm NN cord-027201-owzhv0xy 103 3 2 2 CD cord-027201-owzhv0xy 103 4 lines line NNS cord-027201-owzhv0xy 103 5 3 3 CD cord-027201-owzhv0xy 103 6 - - SYM cord-027201-owzhv0xy 103 7 6 6 CD cord-027201-owzhv0xy 103 8 ) ) -RRB- cord-027201-owzhv0xy 103 9 . . . cord-027201-owzhv0xy 104 1 Thanks thank NNS cord-027201-owzhv0xy 104 2 to to IN cord-027201-owzhv0xy 104 3 ε ε NNP cord-027201-owzhv0xy 104 4 a a DT cord-027201-owzhv0xy 104 5 possibility possibility NN cord-027201-owzhv0xy 104 6 that that IN cord-027201-owzhv0xy 104 7 new new JJ cord-027201-owzhv0xy 104 8 sphere sphere NN cord-027201-owzhv0xy 104 9 could could MD cord-027201-owzhv0xy 104 10 be be VB cord-027201-owzhv0xy 104 11 a a DT cord-027201-owzhv0xy 104 12 little little JJ cord-027201-owzhv0xy 104 13 too too RB cord-027201-owzhv0xy 104 14 far far RB cord-027201-owzhv0xy 104 15 , , , cord-027201-owzhv0xy 104 16 or or CC cord-027201-owzhv0xy 104 17 too too RB cord-027201-owzhv0xy 104 18 close close JJ cord-027201-owzhv0xy 104 19 the the DT cord-027201-owzhv0xy 104 20 previous previous JJ cord-027201-owzhv0xy 104 21 S S NNP cord-027201-owzhv0xy 104 22 i i NN cord-027201-owzhv0xy 104 23 . . . cord-027201-owzhv0xy 105 1 The the DT cord-027201-owzhv0xy 105 2 fine fine JJ cord-027201-owzhv0xy 105 3 - - HYPH cord-027201-owzhv0xy 105 4 tuning tuning NN cord-027201-owzhv0xy 105 5 is be VBZ cord-027201-owzhv0xy 105 6 made make VBN cord-027201-owzhv0xy 105 7 by by IN cord-027201-owzhv0xy 105 8 an an DT cord-027201-owzhv0xy 105 9 additional additional JJ cord-027201-owzhv0xy 105 10 function function NN cord-027201-owzhv0xy 105 11 that that WDT cord-027201-owzhv0xy 105 12 checks check VBZ cord-027201-owzhv0xy 105 13 the the DT cord-027201-owzhv0xy 105 14 distance distance NN cord-027201-owzhv0xy 105 15 from from IN cord-027201-owzhv0xy 105 16 the the DT cord-027201-owzhv0xy 105 17 previous previous JJ cord-027201-owzhv0xy 105 18 sphere sphere NN cord-027201-owzhv0xy 105 19 ( ( -LRB- cord-027201-owzhv0xy 105 20 Algorithm algorithm NN cord-027201-owzhv0xy 105 21 2 2 CD cord-027201-owzhv0xy 105 22 lines line NNS cord-027201-owzhv0xy 105 23 7 7 CD cord-027201-owzhv0xy 105 24 - - SYM cord-027201-owzhv0xy 105 25 8 8 CD cord-027201-owzhv0xy 105 26 ) ) -RRB- cord-027201-owzhv0xy 105 27 . . . cord-027201-owzhv0xy 106 1 Additional additional JJ cord-027201-owzhv0xy 106 2 code code NN cord-027201-owzhv0xy 106 3 for for IN cord-027201-owzhv0xy 106 4 stuck stuck JJ cord-027201-owzhv0xy 106 5 detection detection NN cord-027201-owzhv0xy 106 6 that that WDT cord-027201-owzhv0xy 106 7 triggers trigger VBZ cord-027201-owzhv0xy 106 8 restarting restart VBG cord-027201-owzhv0xy 106 9 computations computation NNS cord-027201-owzhv0xy 106 10 are be VBP cord-027201-owzhv0xy 106 11 in in IN cord-027201-owzhv0xy 106 12 ( ( -LRB- cord-027201-owzhv0xy 106 13 Algorithm algorithm NN cord-027201-owzhv0xy 106 14 2 2 CD cord-027201-owzhv0xy 106 15 lines line NNS cord-027201-owzhv0xy 106 16 12 12 CD cord-027201-owzhv0xy 106 17 - - SYM cord-027201-owzhv0xy 106 18 14 14 CD cord-027201-owzhv0xy 106 19 ) ) -RRB- cord-027201-owzhv0xy 106 20 . . . cord-027201-owzhv0xy 107 1 new new JJ cord-027201-owzhv0xy 107 2 sphere sphere NNP cord-027201-owzhv0xy 107 3 x x SYM cord-027201-owzhv0xy 107 4 = = SYM cord-027201-owzhv0xy 107 5 previous previous JJ cord-027201-owzhv0xy 107 6 sphere sphere NN cord-027201-owzhv0xy 107 7 x x NN cord-027201-owzhv0xy 107 8 ± ± NNP cord-027201-owzhv0xy 107 9 random(0 random(0 NN cord-027201-owzhv0xy 107 10 , , . cord-027201-owzhv0xy 108 1 2 2 LS cord-027201-owzhv0xy 108 2 · · NFP cord-027201-owzhv0xy 108 3 r r NN cord-027201-owzhv0xy 108 4 + + SYM cord-027201-owzhv0xy 108 5 2 2 CD cord-027201-owzhv0xy 108 6 · · NFP cord-027201-owzhv0xy 108 7 ε ε NN cord-027201-owzhv0xy 108 8 ) ) -RRB- cord-027201-owzhv0xy 108 9 6 6 CD cord-027201-owzhv0xy 108 10 new new JJ cord-027201-owzhv0xy 108 11 sphere sphere NN cord-027201-owzhv0xy 108 12 y y NNP cord-027201-owzhv0xy 108 13 = = SYM cord-027201-owzhv0xy 108 14 previous previous JJ cord-027201-owzhv0xy 108 15 spherey spherey NNP cord-027201-owzhv0xy 108 16 ± ± NNP cord-027201-owzhv0xy 108 17 random(0 random(0 NNP cord-027201-owzhv0xy 108 18 , , . cord-027201-owzhv0xy 109 1 2 2 LS cord-027201-owzhv0xy 109 2 · · NFP cord-027201-owzhv0xy 109 3 r r NN cord-027201-owzhv0xy 109 4 + + CC cord-027201-owzhv0xy 110 1 2 2 LS cord-027201-owzhv0xy 110 2 · · NFP cord-027201-owzhv0xy 110 3 ε ε NN cord-027201-owzhv0xy 110 4 ) ) -RRB- cord-027201-owzhv0xy 110 5 7 7 CD cord-027201-owzhv0xy 110 6 new new JJ cord-027201-owzhv0xy 110 7 sphere sphere NN cord-027201-owzhv0xy 110 8 z z NN cord-027201-owzhv0xy 110 9 = = SYM cord-027201-owzhv0xy 110 10 previous previous JJ cord-027201-owzhv0xy 110 11 spherez spherez NNP cord-027201-owzhv0xy 110 12 ± ± NNP cord-027201-owzhv0xy 110 13 random(0 random(0 NNP cord-027201-owzhv0xy 110 14 , , , cord-027201-owzhv0xy 110 15 2 2 CD cord-027201-owzhv0xy 110 16 · · NFP cord-027201-owzhv0xy 110 17 r r NN cord-027201-owzhv0xy 110 18 + + SYM cord-027201-owzhv0xy 110 19 2 2 CD cord-027201-owzhv0xy 110 20 · · NFP cord-027201-owzhv0xy 110 21 ε ε NNP cord-027201-owzhv0xy 110 22 ) ) -RRB- cord-027201-owzhv0xy 110 23 ; ; : cord-027201-owzhv0xy 110 24 8 8 CD cord-027201-owzhv0xy 110 25 check check NN cord-027201-owzhv0xy 110 26 distance distance NN cord-027201-owzhv0xy 110 27 from from IN cord-027201-owzhv0xy 110 28 previous previous JJ cord-027201-owzhv0xy 110 29 sphere sphere NN cord-027201-owzhv0xy 111 1 This this DT cord-027201-owzhv0xy 111 2 makes make VBZ cord-027201-owzhv0xy 111 3 the the DT cord-027201-owzhv0xy 111 4 simulation simulation NN cord-027201-owzhv0xy 111 5 of of IN cord-027201-owzhv0xy 111 6 CD CD NNP cord-027201-owzhv0xy 111 7 process process NN cord-027201-owzhv0xy 111 8 long long RB cord-027201-owzhv0xy 111 9 and and CC cord-027201-owzhv0xy 111 10 inefficient inefficient JJ cord-027201-owzhv0xy 111 11 , , , cord-027201-owzhv0xy 111 12 and and CC cord-027201-owzhv0xy 111 13 the the DT cord-027201-owzhv0xy 111 14 result result NN cord-027201-owzhv0xy 111 15 was be VBD cord-027201-owzhv0xy 111 16 disappointed disappoint VBN cord-027201-owzhv0xy 111 17 : : : cord-027201-owzhv0xy 111 18 the the DT cord-027201-owzhv0xy 111 19 algorithm algorithm NN cord-027201-owzhv0xy 111 20 got get VBD cord-027201-owzhv0xy 111 21 stuck stick VBN cord-027201-owzhv0xy 111 22 relatively relatively RB cord-027201-owzhv0xy 111 23 often often RB cord-027201-owzhv0xy 111 24 . . . cord-027201-owzhv0xy 112 1 The the DT cord-027201-owzhv0xy 112 2 measured measure VBN cord-027201-owzhv0xy 112 3 number number NN cord-027201-owzhv0xy 112 4 of of IN cord-027201-owzhv0xy 112 5 necessary necessary JJ cord-027201-owzhv0xy 112 6 restarts restart NNS cord-027201-owzhv0xy 112 7 to to TO cord-027201-owzhv0xy 112 8 complete complete VB cord-027201-owzhv0xy 112 9 model model NN cord-027201-owzhv0xy 112 10 creation creation NN cord-027201-owzhv0xy 112 11 is be VBZ cord-027201-owzhv0xy 112 12 shown show VBN cord-027201-owzhv0xy 112 13 in in IN cord-027201-owzhv0xy 112 14 Table Table NNP cord-027201-owzhv0xy 112 15 1 1 CD cord-027201-owzhv0xy 112 16 . . . cord-027201-owzhv0xy 113 1 In in IN cord-027201-owzhv0xy 113 2 one one CD cord-027201-owzhv0xy 113 3 model model NN cord-027201-owzhv0xy 113 4 creation creation NN cord-027201-owzhv0xy 113 5 , , , cord-027201-owzhv0xy 113 6 about about RB cord-027201-owzhv0xy 113 7 650 650 CD cord-027201-owzhv0xy 113 8 spheres sphere NNS cord-027201-owzhv0xy 113 9 should should MD cord-027201-owzhv0xy 113 10 be be VB cord-027201-owzhv0xy 113 11 placed place VBN cord-027201-owzhv0xy 113 12 as as IN cord-027201-owzhv0xy 113 13 the the DT cord-027201-owzhv0xy 113 14 tangent tangent JJ cord-027201-owzhv0xy 113 15 ones one NNS cord-027201-owzhv0xy 113 16 , , , cord-027201-owzhv0xy 113 17 so so CC cord-027201-owzhv0xy 113 18 it -PRON- PRP cord-027201-owzhv0xy 113 19 was be VBD cord-027201-owzhv0xy 113 20 easy easy JJ cord-027201-owzhv0xy 113 21 to to TO cord-027201-owzhv0xy 113 22 asses ass NNS cord-027201-owzhv0xy 113 23 the the DT cord-027201-owzhv0xy 113 24 number number NN cord-027201-owzhv0xy 113 25 of of IN cord-027201-owzhv0xy 113 26 inefficient inefficient JJ cord-027201-owzhv0xy 113 27 searches search NNS cord-027201-owzhv0xy 113 28 -they -they WP cord-027201-owzhv0xy 113 29 are be VBP cord-027201-owzhv0xy 113 30 presented present VBN cord-027201-owzhv0xy 113 31 in in IN cord-027201-owzhv0xy 113 32 the the DT cord-027201-owzhv0xy 113 33 last last JJ cord-027201-owzhv0xy 113 34 column column NN cord-027201-owzhv0xy 113 35 of of IN cord-027201-owzhv0xy 113 36 Table Table NNP cord-027201-owzhv0xy 113 37 1 1 CD cord-027201-owzhv0xy 113 38 . . . cord-027201-owzhv0xy 114 1 Table table NN cord-027201-owzhv0xy 114 2 2 2 CD cord-027201-owzhv0xy 114 3 showed show VBD cord-027201-owzhv0xy 114 4 the the DT cord-027201-owzhv0xy 114 5 time time NN cord-027201-owzhv0xy 114 6 needed need VBN cord-027201-owzhv0xy 114 7 to to TO cord-027201-owzhv0xy 114 8 generate generate VB cord-027201-owzhv0xy 114 9 one one CD cord-027201-owzhv0xy 114 10 CT CT NNP cord-027201-owzhv0xy 114 11 model model NN cord-027201-owzhv0xy 114 12 . . . cord-027201-owzhv0xy 115 1 Time time NN cord-027201-owzhv0xy 115 2 was be VBD cord-027201-owzhv0xy 115 3 measured measure VBN cord-027201-owzhv0xy 115 4 in in IN cord-027201-owzhv0xy 115 5 seconds second NNS cord-027201-owzhv0xy 115 6 , , , cord-027201-owzhv0xy 115 7 basic basic JJ cord-027201-owzhv0xy 115 8 statistics statistic NNS cord-027201-owzhv0xy 115 9 were be VBD cord-027201-owzhv0xy 115 10 also also RB cord-027201-owzhv0xy 115 11 given give VBN cord-027201-owzhv0xy 115 12 , , , cord-027201-owzhv0xy 115 13 measurements measurement NNS cord-027201-owzhv0xy 115 14 were be VBD cord-027201-owzhv0xy 115 15 made make VBN cord-027201-owzhv0xy 115 16 on on IN cord-027201-owzhv0xy 115 17 40 40 CD cord-027201-owzhv0xy 115 18 generated generate VBN cord-027201-owzhv0xy 115 19 models model NNS cord-027201-owzhv0xy 115 20 . . . cord-027201-owzhv0xy 116 1 That that DT cord-027201-owzhv0xy 116 2 was be VBD cord-027201-owzhv0xy 116 3 not not RB cord-027201-owzhv0xy 116 4 a a DT cord-027201-owzhv0xy 116 5 satisfactory satisfactory JJ cord-027201-owzhv0xy 116 6 result result NN cord-027201-owzhv0xy 116 7 . . . cord-027201-owzhv0xy 117 1 We -PRON- PRP cord-027201-owzhv0xy 117 2 had have VBD cord-027201-owzhv0xy 117 3 to to TO cord-027201-owzhv0xy 117 4 rethink rethink VB cord-027201-owzhv0xy 117 5 the the DT cord-027201-owzhv0xy 117 6 way way NN cord-027201-owzhv0xy 117 7 we -PRON- PRP cord-027201-owzhv0xy 117 8 implement implement VBP cord-027201-owzhv0xy 117 9 the the DT cord-027201-owzhv0xy 117 10 decondensation decondensation NN cord-027201-owzhv0xy 117 11 of of IN cord-027201-owzhv0xy 117 12 chromatin chromatin NN cord-027201-owzhv0xy 117 13 . . . cord-027201-owzhv0xy 118 1 We -PRON- PRP cord-027201-owzhv0xy 118 2 decided decide VBD cord-027201-owzhv0xy 118 3 to to TO cord-027201-owzhv0xy 118 4 try try VB cord-027201-owzhv0xy 118 5 to to TO cord-027201-owzhv0xy 118 6 add add VB cord-027201-owzhv0xy 118 7 -at -at HYPH cord-027201-owzhv0xy 118 8 first first JJ cord-027201-owzhv0xy 118 9 sightadditional sightadditional JJ cord-027201-owzhv0xy 118 10 computations computation NNS cord-027201-owzhv0xy 118 11 : : : cord-027201-owzhv0xy 118 12 shifting shift VBG cord-027201-owzhv0xy 118 13 ( ( -LRB- cord-027201-owzhv0xy 118 14 change change NN cord-027201-owzhv0xy 118 15 location location NN cord-027201-owzhv0xy 118 16 ) ) -RRB- cord-027201-owzhv0xy 118 17 of of IN cord-027201-owzhv0xy 118 18 the the DT cord-027201-owzhv0xy 118 19 center center NN cord-027201-owzhv0xy 118 20 of of IN cord-027201-owzhv0xy 118 21 coordinate coordinate JJ cord-027201-owzhv0xy 118 22 systems system NNS cord-027201-owzhv0xy 118 23 . . . cord-027201-owzhv0xy 119 1 Then then RB cord-027201-owzhv0xy 119 2 we -PRON- PRP cord-027201-owzhv0xy 119 3 were be VBD cord-027201-owzhv0xy 119 4 able able JJ cord-027201-owzhv0xy 119 5 to to TO cord-027201-owzhv0xy 119 6 use use VB cord-027201-owzhv0xy 119 7 the the DT cord-027201-owzhv0xy 119 8 notion notion NN cord-027201-owzhv0xy 119 9 of of IN cord-027201-owzhv0xy 119 10 the the DT cord-027201-owzhv0xy 119 11 neighborhood neighborhood NN cord-027201-owzhv0xy 119 12 with with IN cord-027201-owzhv0xy 119 13 a a DT cord-027201-owzhv0xy 119 14 fixed fix VBN cord-027201-owzhv0xy 119 15 radius radius NN cord-027201-owzhv0xy 119 16 ( ( -LRB- cord-027201-owzhv0xy 119 17 inspired inspire VBN cord-027201-owzhv0xy 119 18 by by IN cord-027201-owzhv0xy 119 19 a a DT cord-027201-owzhv0xy 119 20 topology topology NN cord-027201-owzhv0xy 119 21 ) ) -RRB- cord-027201-owzhv0xy 119 22 and and CC cord-027201-owzhv0xy 119 23 use use VB cord-027201-owzhv0xy 119 24 spherical spherical JJ cord-027201-owzhv0xy 119 25 coordinates coordinate NNS cord-027201-owzhv0xy 119 26 ( ( -LRB- cord-027201-owzhv0xy 119 27 see see VB cord-027201-owzhv0xy 119 28 Fig Fig NNP cord-027201-owzhv0xy 119 29 . . NNP cord-027201-owzhv0xy 119 30 4 4 CD cord-027201-owzhv0xy 119 31 ) ) -RRB- cord-027201-owzhv0xy 119 32 . . . cord-027201-owzhv0xy 120 1 We -PRON- PRP cord-027201-owzhv0xy 120 2 were be VBD cord-027201-owzhv0xy 120 3 aware aware JJ cord-027201-owzhv0xy 120 4 of of IN cord-027201-owzhv0xy 120 5 the the DT cord-027201-owzhv0xy 120 6 fact fact NN cord-027201-owzhv0xy 120 7 that that IN cord-027201-owzhv0xy 120 8 shifting shift VBG cord-027201-owzhv0xy 120 9 the the DT cord-027201-owzhv0xy 120 10 coordinate coordinate JJ cord-027201-owzhv0xy 120 11 system system NN cord-027201-owzhv0xy 120 12 takes take VBZ cord-027201-owzhv0xy 120 13 additional additional JJ cord-027201-owzhv0xy 120 14 time time NN cord-027201-owzhv0xy 120 15 -but -but . cord-027201-owzhv0xy 121 1 the the DT cord-027201-owzhv0xy 121 2 solution solution NN cord-027201-owzhv0xy 121 3 with with IN cord-027201-owzhv0xy 121 4 CC CC NNP cord-027201-owzhv0xy 121 5 works work NNS cord-027201-owzhv0xy 121 6 so so RB cord-027201-owzhv0xy 121 7 bad bad RB cord-027201-owzhv0xy 121 8 , , , cord-027201-owzhv0xy 121 9 that that IN cord-027201-owzhv0xy 121 10 we -PRON- PRP cord-027201-owzhv0xy 121 11 hope hope VBP cord-027201-owzhv0xy 121 12 that that IN cord-027201-owzhv0xy 121 13 this this DT cord-027201-owzhv0xy 121 14 approach approach NN cord-027201-owzhv0xy 121 15 will will MD cord-027201-owzhv0xy 121 16 work work VB cord-027201-owzhv0xy 121 17 a a DT cord-027201-owzhv0xy 121 18 little little JJ cord-027201-owzhv0xy 121 19 better well JJR cord-027201-owzhv0xy 121 20 . . . cord-027201-owzhv0xy 122 1 The the DT cord-027201-owzhv0xy 122 2 result result NN cord-027201-owzhv0xy 122 3 of of IN cord-027201-owzhv0xy 122 4 this this DT cord-027201-owzhv0xy 122 5 change change NN cord-027201-owzhv0xy 122 6 beats beat VBZ cord-027201-owzhv0xy 122 7 our -PRON- PRP$ cord-027201-owzhv0xy 122 8 expectations expectation NNS cord-027201-owzhv0xy 122 9 -which -which WP$ cord-027201-owzhv0xy 122 10 is be VBZ cord-027201-owzhv0xy 122 11 described describe VBN cord-027201-owzhv0xy 122 12 and and CC cord-027201-owzhv0xy 122 13 documented document VBN cord-027201-owzhv0xy 122 14 in in IN cord-027201-owzhv0xy 122 15 the the DT cord-027201-owzhv0xy 122 16 next next JJ cord-027201-owzhv0xy 122 17 sections section NNS cord-027201-owzhv0xy 122 18 . . . cord-027201-owzhv0xy 123 1 We -PRON- PRP cord-027201-owzhv0xy 123 2 decided decide VBD cord-027201-owzhv0xy 123 3 to to TO cord-027201-owzhv0xy 123 4 try try VB cord-027201-owzhv0xy 123 5 Spherical spherical JJ cord-027201-owzhv0xy 123 6 Coordinates Coordinates NNPS cord-027201-owzhv0xy 123 7 ( ( -LRB- cord-027201-owzhv0xy 123 8 SC SC NNP cord-027201-owzhv0xy 123 9 ) ) -RRB- cord-027201-owzhv0xy 123 10 [ [ -LRB- cord-027201-owzhv0xy 123 11 27 27 CD cord-027201-owzhv0xy 123 12 ] ] -RRB- cord-027201-owzhv0xy 123 13 instead instead RB cord-027201-owzhv0xy 123 14 of of IN cord-027201-owzhv0xy 123 15 CC CC NNP cord-027201-owzhv0xy 123 16 ( ( -LRB- cord-027201-owzhv0xy 123 17 for for IN cord-027201-owzhv0xy 123 18 those those DT cord-027201-owzhv0xy 123 19 , , , cord-027201-owzhv0xy 123 20 who who WP cord-027201-owzhv0xy 123 21 are be VBP cord-027201-owzhv0xy 123 22 not not RB cord-027201-owzhv0xy 123 23 familiar familiar JJ cord-027201-owzhv0xy 123 24 with with IN cord-027201-owzhv0xy 123 25 different different JJ cord-027201-owzhv0xy 123 26 coordinate coordinate JJ cord-027201-owzhv0xy 123 27 systems system NNS cord-027201-owzhv0xy 123 28 we -PRON- PRP cord-027201-owzhv0xy 123 29 recommend recommend VBP cord-027201-owzhv0xy 123 30 to to TO cord-027201-owzhv0xy 123 31 take take VB cord-027201-owzhv0xy 123 32 a a DT cord-027201-owzhv0xy 123 33 look look NN cord-027201-owzhv0xy 123 34 at at IN cord-027201-owzhv0xy 123 35 [ [ -LRB- cord-027201-owzhv0xy 123 36 28 28 CD cord-027201-owzhv0xy 123 37 ] ] -RRB- cord-027201-owzhv0xy 123 38 , , , cord-027201-owzhv0xy 123 39 [ [ -LRB- cord-027201-owzhv0xy 123 40 29 29 CD cord-027201-owzhv0xy 123 41 ] ] -RRB- cord-027201-owzhv0xy 123 42 ) ) -RRB- cord-027201-owzhv0xy 123 43 . . . cord-027201-owzhv0xy 124 1 When when WRB cord-027201-owzhv0xy 124 2 we -PRON- PRP cord-027201-owzhv0xy 124 3 wanted want VBD cord-027201-owzhv0xy 124 4 to to TO cord-027201-owzhv0xy 124 5 add add VB cord-027201-owzhv0xy 124 6 sphere sphere JJ cord-027201-owzhv0xy 124 7 S s NN cord-027201-owzhv0xy 124 8 i+1 i+1 NN cord-027201-owzhv0xy 124 9 to to IN cord-027201-owzhv0xy 124 10 the the DT cord-027201-owzhv0xy 124 11 certain certain JJ cord-027201-owzhv0xy 124 12 one one NN cord-027201-owzhv0xy 124 13 S s NN cord-027201-owzhv0xy 124 14 i i NN cord-027201-owzhv0xy 124 15 , , , cord-027201-owzhv0xy 124 16 we -PRON- PRP cord-027201-owzhv0xy 124 17 first first RB cord-027201-owzhv0xy 124 18 made make VBD cord-027201-owzhv0xy 124 19 a a DT cord-027201-owzhv0xy 124 20 shift shift NN cord-027201-owzhv0xy 124 21 of of IN cord-027201-owzhv0xy 124 22 the the DT cord-027201-owzhv0xy 124 23 center center NN cord-027201-owzhv0xy 124 24 of of IN cord-027201-owzhv0xy 124 25 the the DT cord-027201-owzhv0xy 124 26 coordinate coordinate JJ cord-027201-owzhv0xy 124 27 system system NN cord-027201-owzhv0xy 124 28 in in IN cord-027201-owzhv0xy 124 29 such such PDT cord-027201-owzhv0xy 124 30 a a DT cord-027201-owzhv0xy 124 31 way way NN cord-027201-owzhv0xy 124 32 , , , cord-027201-owzhv0xy 124 33 that that IN cord-027201-owzhv0xy 124 34 the the DT cord-027201-owzhv0xy 124 35 center center NN cord-027201-owzhv0xy 124 36 of of IN cord-027201-owzhv0xy 124 37 coordinate coordinate JJ cord-027201-owzhv0xy 124 38 system system NN cord-027201-owzhv0xy 124 39 was be VBD cord-027201-owzhv0xy 124 40 situated situate VBN cord-027201-owzhv0xy 124 41 in in IN cord-027201-owzhv0xy 124 42 the the DT cord-027201-owzhv0xy 124 43 middle middle NN cord-027201-owzhv0xy 124 44 of of IN cord-027201-owzhv0xy 124 45 S s NN cord-027201-owzhv0xy 125 1 i i PRP cord-027201-owzhv0xy 125 2 sphere sphere VBP cord-027201-owzhv0xy 125 3 ( ( -LRB- cord-027201-owzhv0xy 125 4 see see VB cord-027201-owzhv0xy 125 5 Fig Fig NNP cord-027201-owzhv0xy 125 6 . . NNP cord-027201-owzhv0xy 125 7 4 4 CD cord-027201-owzhv0xy 125 8 ) ) -RRB- cord-027201-owzhv0xy 125 9 . . . cord-027201-owzhv0xy 126 1 This this DT cord-027201-owzhv0xy 126 2 let let VB cord-027201-owzhv0xy 126 3 us -PRON- PRP cord-027201-owzhv0xy 126 4 search search VB cord-027201-owzhv0xy 126 5 for for IN cord-027201-owzhv0xy 126 6 the the DT cord-027201-owzhv0xy 126 7 S S NNP cord-027201-owzhv0xy 126 8 i+1 i+1 NN cord-027201-owzhv0xy 126 9 by by IN cord-027201-owzhv0xy 126 10 drawing draw VBG cord-027201-owzhv0xy 126 11 two two CD cord-027201-owzhv0xy 126 12 angles angle NNS cord-027201-owzhv0xy 126 13 and and CC cord-027201-owzhv0xy 126 14 using use VBG cord-027201-owzhv0xy 126 15 just just RB cord-027201-owzhv0xy 126 16 one one CD cord-027201-owzhv0xy 126 17 parameter parameter NN cord-027201-owzhv0xy 126 18 : : : cord-027201-owzhv0xy 126 19 2r 2r CD cord-027201-owzhv0xy 126 20 . . . cord-027201-owzhv0xy 127 1 After after IN cord-027201-owzhv0xy 127 2 switching switch VBG cord-027201-owzhv0xy 127 3 to to IN cord-027201-owzhv0xy 127 4 the the DT cord-027201-owzhv0xy 127 5 SC SC NNP cord-027201-owzhv0xy 127 6 , , , cord-027201-owzhv0xy 127 7 we -PRON- PRP cord-027201-owzhv0xy 127 8 got get VBD cord-027201-owzhv0xy 127 9 rid rid VBN cord-027201-owzhv0xy 127 10 of of IN cord-027201-owzhv0xy 127 11 the the DT cord-027201-owzhv0xy 127 12 problem problem NN cord-027201-owzhv0xy 127 13 of of IN cord-027201-owzhv0xy 127 14 looping loop VBG cord-027201-owzhv0xy 127 15 the the DT cord-027201-owzhv0xy 127 16 simulation simulation NN cord-027201-owzhv0xy 127 17 during during IN cord-027201-owzhv0xy 127 18 attempts attempt NNS cord-027201-owzhv0xy 127 19 of of IN cord-027201-owzhv0xy 127 20 finding find VBG cord-027201-owzhv0xy 127 21 the the DT cord-027201-owzhv0xy 127 22 location location NN cord-027201-owzhv0xy 127 23 for for IN cord-027201-owzhv0xy 127 24 the the DT cord-027201-owzhv0xy 127 25 S S NNP cord-027201-owzhv0xy 127 26 i+1 i+1 NN cord-027201-owzhv0xy 127 27 . . . cord-027201-owzhv0xy 128 1 Therefore therefore RB cord-027201-owzhv0xy 128 2 , , , cord-027201-owzhv0xy 128 3 the the DT cord-027201-owzhv0xy 128 4 function function NN cord-027201-owzhv0xy 128 5 that that WDT cord-027201-owzhv0xy 128 6 restarts restart VBZ cord-027201-owzhv0xy 128 7 CT CT NNP cord-027201-owzhv0xy 128 8 model model NN cord-027201-owzhv0xy 128 9 creation creation NN cord-027201-owzhv0xy 128 10 could could MD cord-027201-owzhv0xy 128 11 be be VB cord-027201-owzhv0xy 128 12 removed remove VBN cord-027201-owzhv0xy 128 13 . . . cord-027201-owzhv0xy 129 1 We -PRON- PRP cord-027201-owzhv0xy 129 2 made make VBD cord-027201-owzhv0xy 129 3 measurements measurement NNS cord-027201-owzhv0xy 129 4 -time -time RB cord-027201-owzhv0xy 129 5 necessary necessary JJ cord-027201-owzhv0xy 129 6 to to TO cord-027201-owzhv0xy 129 7 generate generate VB cord-027201-owzhv0xy 129 8 CT CT NNP cord-027201-owzhv0xy 129 9 models model NNS cord-027201-owzhv0xy 129 10 ( ( -LRB- cord-027201-owzhv0xy 129 11 equivalent equivalent JJ cord-027201-owzhv0xy 129 12 to to IN cord-027201-owzhv0xy 129 13 the the DT cord-027201-owzhv0xy 129 14 time time NN cord-027201-owzhv0xy 129 15 of of IN cord-027201-owzhv0xy 129 16 CD CD NNP cord-027201-owzhv0xy 129 17 simulation simulation NN cord-027201-owzhv0xy 129 18 ) ) -RRB- cord-027201-owzhv0xy 129 19 with with IN cord-027201-owzhv0xy 129 20 shifting shift VBG cord-027201-owzhv0xy 129 21 coordinate coordinate JJ cord-027201-owzhv0xy 129 22 system system NN cord-027201-owzhv0xy 129 23 and and CC cord-027201-owzhv0xy 129 24 using use VBG cord-027201-owzhv0xy 129 25 spherical spherical JJ cord-027201-owzhv0xy 129 26 coordinates coordinate NNS cord-027201-owzhv0xy 129 27 is be VBZ cord-027201-owzhv0xy 129 28 presented present VBN cord-027201-owzhv0xy 129 29 in in IN cord-027201-owzhv0xy 129 30 Table Table NNP cord-027201-owzhv0xy 129 31 3 3 CD cord-027201-owzhv0xy 129 32 . . . cord-027201-owzhv0xy 130 1 Time time NN cord-027201-owzhv0xy 130 2 of of IN cord-027201-owzhv0xy 130 3 creating create VBG cord-027201-owzhv0xy 130 4 CT CT NNP cord-027201-owzhv0xy 130 5 models model NNS cord-027201-owzhv0xy 130 6 decreases decrease VBZ cord-027201-owzhv0xy 130 7 significantly significantly RB cord-027201-owzhv0xy 130 8 in in IN cord-027201-owzhv0xy 130 9 comparison comparison NN cord-027201-owzhv0xy 130 10 to to IN cord-027201-owzhv0xy 130 11 the the DT cord-027201-owzhv0xy 130 12 use use NN cord-027201-owzhv0xy 130 13 of of IN cord-027201-owzhv0xy 130 14 CC CC NNP cord-027201-owzhv0xy 130 15 . . . cord-027201-owzhv0xy 131 1 This this DT cord-027201-owzhv0xy 131 2 had have VBD cord-027201-owzhv0xy 131 3 a a DT cord-027201-owzhv0xy 131 4 direct direct JJ cord-027201-owzhv0xy 131 5 and and CC cord-027201-owzhv0xy 131 6 significant significant JJ cord-027201-owzhv0xy 131 7 impact impact NN cord-027201-owzhv0xy 131 8 on on IN cord-027201-owzhv0xy 131 9 the the DT cord-027201-owzhv0xy 131 10 time time NN cord-027201-owzhv0xy 131 11 of of IN cord-027201-owzhv0xy 131 12 the the DT cord-027201-owzhv0xy 131 13 model model NN cord-027201-owzhv0xy 131 14 creation creation NN cord-027201-owzhv0xy 131 15 . . . cord-027201-owzhv0xy 132 1 6 6 CD cord-027201-owzhv0xy 132 2 new new JJ cord-027201-owzhv0xy 132 3 sphere sphere NN cord-027201-owzhv0xy 132 4 x x NN cord-027201-owzhv0xy 132 5 = = SYM cord-027201-owzhv0xy 132 6 previous previous JJ cord-027201-owzhv0xy 132 7 sphere sphere NN cord-027201-owzhv0xy 132 8 x x SYM cord-027201-owzhv0xy 132 9 + + SYM cord-027201-owzhv0xy 132 10 2 2 CD cord-027201-owzhv0xy 132 11 · · NFP cord-027201-owzhv0xy 132 12 r r NN cord-027201-owzhv0xy 132 13 · · NFP cord-027201-owzhv0xy 132 14 cos(ψ cos(ψ NN cord-027201-owzhv0xy 132 15 ) ) -RRB- cord-027201-owzhv0xy 132 16 · · NFP cord-027201-owzhv0xy 132 17 sin(φ sin(φ JJS cord-027201-owzhv0xy 132 18 ) ) -RRB- cord-027201-owzhv0xy 133 1 new new NNP cord-027201-owzhv0xy 133 2 sphere sphere NNP cord-027201-owzhv0xy 133 3 y y NNP cord-027201-owzhv0xy 133 4 = = NFP cord-027201-owzhv0xy 133 5 previous previous JJ cord-027201-owzhv0xy 133 6 sphere sphere NNP cord-027201-owzhv0xy 133 7 y y NNP cord-027201-owzhv0xy 133 8 + + CC cord-027201-owzhv0xy 134 1 2 2 LS cord-027201-owzhv0xy 134 2 · · NFP cord-027201-owzhv0xy 134 3 r r NN cord-027201-owzhv0xy 134 4 · · NFP cord-027201-owzhv0xy 134 5 sin(ψ sin(ψ NNP cord-027201-owzhv0xy 134 6 ) ) -RRB- cord-027201-owzhv0xy 134 7 · · NFP cord-027201-owzhv0xy 134 8 sin(φ sin(φ JJS cord-027201-owzhv0xy 134 9 ) ) -RRB- cord-027201-owzhv0xy 135 1 new new NNP cord-027201-owzhv0xy 135 2 sphere sphere NNP cord-027201-owzhv0xy 135 3 z z NNP cord-027201-owzhv0xy 135 4 = = SYM cord-027201-owzhv0xy 135 5 previous previous JJ cord-027201-owzhv0xy 135 6 sphere sphere NN cord-027201-owzhv0xy 135 7 z z NN cord-027201-owzhv0xy 135 8 + + SYM cord-027201-owzhv0xy 135 9 2 2 CD cord-027201-owzhv0xy 135 10 · · NFP cord-027201-owzhv0xy 135 11 r r NN cord-027201-owzhv0xy 135 12 · · NFP cord-027201-owzhv0xy 135 13 cos(φ cos(φ '' cord-027201-owzhv0xy 135 14 ) ) -RRB- cord-027201-owzhv0xy 135 15 ; ; : cord-027201-owzhv0xy 135 16 7 7 CD cord-027201-owzhv0xy 135 17 is be VBZ cord-027201-owzhv0xy 135 18 inside inside IN cord-027201-owzhv0xy 135 19 nucleus nucleus NN cord-027201-owzhv0xy 135 20 ; ; : cord-027201-owzhv0xy 135 21 _SP cord-027201-owzhv0xy 136 1 To to TO cord-027201-owzhv0xy 136 2 follow follow VB cord-027201-owzhv0xy 136 3 the the DT cord-027201-owzhv0xy 136 4 rigor rigor NN cord-027201-owzhv0xy 136 5 for for IN cord-027201-owzhv0xy 136 6 scientific scientific JJ cord-027201-owzhv0xy 136 7 publications publication NNS cord-027201-owzhv0xy 136 8 ( ( -LRB- cord-027201-owzhv0xy 136 9 despite despite IN cord-027201-owzhv0xy 136 10 very very RB cord-027201-owzhv0xy 136 11 clear clear JJ cord-027201-owzhv0xy 136 12 difference difference NN cord-027201-owzhv0xy 136 13 between between IN cord-027201-owzhv0xy 136 14 times time NNS cord-027201-owzhv0xy 136 15 showed show VBD cord-027201-owzhv0xy 136 16 in in IN cord-027201-owzhv0xy 136 17 Table Table NNP cord-027201-owzhv0xy 136 18 2 2 CD cord-027201-owzhv0xy 136 19 and and CC cord-027201-owzhv0xy 136 20 Table Table NNP cord-027201-owzhv0xy 136 21 3 3 CD cord-027201-owzhv0xy 136 22 ) ) -RRB- cord-027201-owzhv0xy 136 23 we -PRON- PRP cord-027201-owzhv0xy 136 24 made make VBD cord-027201-owzhv0xy 136 25 an an DT cord-027201-owzhv0xy 136 26 analysis analysis NN cord-027201-owzhv0xy 136 27 , , , cord-027201-owzhv0xy 136 28 presented present VBN cord-027201-owzhv0xy 136 29 in in IN cord-027201-owzhv0xy 136 30 this this DT cord-027201-owzhv0xy 136 31 section section NN cord-027201-owzhv0xy 136 32 . . . cord-027201-owzhv0xy 137 1 For for IN cord-027201-owzhv0xy 137 2 the the DT cord-027201-owzhv0xy 137 3 purpose purpose NN cord-027201-owzhv0xy 137 4 of of IN cord-027201-owzhv0xy 137 5 visual visual JJ cord-027201-owzhv0xy 137 6 comparison comparison NN cord-027201-owzhv0xy 137 7 of of IN cord-027201-owzhv0xy 137 8 the the DT cord-027201-owzhv0xy 137 9 times time NNS cord-027201-owzhv0xy 137 10 of of IN cord-027201-owzhv0xy 137 11 CT CT NNP cord-027201-owzhv0xy 137 12 model model NN cord-027201-owzhv0xy 137 13 creation creation NN cord-027201-owzhv0xy 137 14 we -PRON- PRP cord-027201-owzhv0xy 137 15 prepared prepare VBD cord-027201-owzhv0xy 137 16 a a DT cord-027201-owzhv0xy 137 17 boxplot boxplot NN cord-027201-owzhv0xy 137 18 ( ( -LRB- cord-027201-owzhv0xy 137 19 see see VB cord-027201-owzhv0xy 137 20 Fig Fig NNP cord-027201-owzhv0xy 137 21 . . . cord-027201-owzhv0xy 137 22 5 5 LS cord-027201-owzhv0xy 137 23 ) ) -RRB- cord-027201-owzhv0xy 137 24 for for IN cord-027201-owzhv0xy 137 25 general general JJ cord-027201-owzhv0xy 137 26 view view NN cord-027201-owzhv0xy 137 27 . . . cord-027201-owzhv0xy 138 1 In in IN cord-027201-owzhv0xy 138 2 Fig Fig NNP cord-027201-owzhv0xy 138 3 . . . cord-027201-owzhv0xy 139 1 5 5 LS cord-027201-owzhv0xy 139 2 the the DT cord-027201-owzhv0xy 139 3 difference difference NN cord-027201-owzhv0xy 139 4 , , , cord-027201-owzhv0xy 139 5 in in IN cord-027201-owzhv0xy 139 6 general general JJ cord-027201-owzhv0xy 139 7 , , , cord-027201-owzhv0xy 139 8 is be VBZ cord-027201-owzhv0xy 139 9 easy easy JJ cord-027201-owzhv0xy 139 10 to to TO cord-027201-owzhv0xy 139 11 notice notice VB cord-027201-owzhv0xy 139 12 . . . cord-027201-owzhv0xy 140 1 There there EX cord-027201-owzhv0xy 140 2 is be VBZ cord-027201-owzhv0xy 140 3 even even RB cord-027201-owzhv0xy 140 4 no no DT cord-027201-owzhv0xy 140 5 single single JJ cord-027201-owzhv0xy 140 6 element element NN cord-027201-owzhv0xy 140 7 of of IN cord-027201-owzhv0xy 140 8 the the DT cord-027201-owzhv0xy 140 9 chart chart NN cord-027201-owzhv0xy 140 10 ( ( -LRB- cord-027201-owzhv0xy 140 11 neither neither CC cord-027201-owzhv0xy 140 12 whiskers whisker NNS cord-027201-owzhv0xy 140 13 nor nor CC cord-027201-owzhv0xy 140 14 dots dot NNS cord-027201-owzhv0xy 140 15 ( ( -LRB- cord-027201-owzhv0xy 140 16 outliers outlier NNS cord-027201-owzhv0xy 140 17 ) ) -RRB- cord-027201-owzhv0xy 140 18 ) ) -RRB- cord-027201-owzhv0xy 140 19 that that WDT cord-027201-owzhv0xy 140 20 overlaps overlap VBZ cord-027201-owzhv0xy 140 21 each each DT cord-027201-owzhv0xy 140 22 other other JJ cord-027201-owzhv0xy 140 23 . . . cord-027201-owzhv0xy 141 1 It -PRON- PRP cord-027201-owzhv0xy 141 2 is be VBZ cord-027201-owzhv0xy 141 3 easy easy JJ cord-027201-owzhv0xy 141 4 to to TO cord-027201-owzhv0xy 141 5 notice notice VB cord-027201-owzhv0xy 141 6 a a DT cord-027201-owzhv0xy 141 7 huge huge JJ cord-027201-owzhv0xy 141 8 difference difference NN cord-027201-owzhv0xy 141 9 between between IN cord-027201-owzhv0xy 141 10 computing compute VBG cord-027201-owzhv0xy 141 11 time time NN cord-027201-owzhv0xy 141 12 ( ( -LRB- cord-027201-owzhv0xy 141 13 and and CC cord-027201-owzhv0xy 141 14 its -PRON- PRP$ cord-027201-owzhv0xy 141 15 stability stability NN cord-027201-owzhv0xy 141 16 ) ) -RRB- cord-027201-owzhv0xy 141 17 in in IN cord-027201-owzhv0xy 141 18 both both DT cord-027201-owzhv0xy 141 19 cases case NNS cord-027201-owzhv0xy 141 20 . . . cord-027201-owzhv0xy 142 1 For for IN cord-027201-owzhv0xy 142 2 the the DT cord-027201-owzhv0xy 142 3 record record NN cord-027201-owzhv0xy 142 4 we -PRON- PRP cord-027201-owzhv0xy 142 5 made make VBD cord-027201-owzhv0xy 142 6 statistical statistical JJ cord-027201-owzhv0xy 142 7 test test NN cord-027201-owzhv0xy 142 8 -the -the DT cord-027201-owzhv0xy 142 9 result result NN cord-027201-owzhv0xy 142 10 is be VBZ cord-027201-owzhv0xy 142 11 presented present VBN cord-027201-owzhv0xy 142 12 in in IN cord-027201-owzhv0xy 142 13 Table Table NNP cord-027201-owzhv0xy 142 14 4 4 CD cord-027201-owzhv0xy 142 15 . . . cord-027201-owzhv0xy 143 1 We -PRON- PRP cord-027201-owzhv0xy 143 2 calculated calculate VBD cord-027201-owzhv0xy 143 3 the the DT cord-027201-owzhv0xy 143 4 value value NN cord-027201-owzhv0xy 143 5 of of IN cord-027201-owzhv0xy 143 6 the the DT cord-027201-owzhv0xy 143 7 t t NN cord-027201-owzhv0xy 143 8 - - HYPH cord-027201-owzhv0xy 143 9 test test NN cord-027201-owzhv0xy 143 10 , , , cord-027201-owzhv0xy 143 11 to to TO cord-027201-owzhv0xy 143 12 confirm confirm VB cord-027201-owzhv0xy 143 13 that that IN cord-027201-owzhv0xy 143 14 the the DT cord-027201-owzhv0xy 143 15 difference difference NN cord-027201-owzhv0xy 143 16 in in IN cord-027201-owzhv0xy 143 17 creation creation NN cord-027201-owzhv0xy 143 18 times time NNS cord-027201-owzhv0xy 143 19 of of IN cord-027201-owzhv0xy 143 20 model model NN cord-027201-owzhv0xy 143 21 ( ( -LRB- cord-027201-owzhv0xy 143 22 CC CC NNP cord-027201-owzhv0xy 143 23 and and CC cord-027201-owzhv0xy 143 24 SC SC NNP cord-027201-owzhv0xy 143 25 ) ) -RRB- cord-027201-owzhv0xy 143 26 is be VBZ cord-027201-owzhv0xy 143 27 statistically statistically RB cord-027201-owzhv0xy 143 28 significant significant JJ cord-027201-owzhv0xy 144 1 ( ( -LRB- cord-027201-owzhv0xy 144 2 p p NN cord-027201-owzhv0xy 144 3 - - HYPH cord-027201-owzhv0xy 144 4 value value NN cord-027201-owzhv0xy 144 5 below below IN cord-027201-owzhv0xy 144 6 0.05 0.05 CD cord-027201-owzhv0xy 144 7 means mean NNS cord-027201-owzhv0xy 144 8 that that IN cord-027201-owzhv0xy 144 9 the the DT cord-027201-owzhv0xy 144 10 difference difference NN cord-027201-owzhv0xy 144 11 is be VBZ cord-027201-owzhv0xy 144 12 statistically statistically RB cord-027201-owzhv0xy 144 13 significant significant JJ cord-027201-owzhv0xy 144 14 ) ) -RRB- cord-027201-owzhv0xy 144 15 . . . cord-027201-owzhv0xy 145 1 This this DT cord-027201-owzhv0xy 145 2 proves prove VBZ cord-027201-owzhv0xy 145 3 the the DT cord-027201-owzhv0xy 145 4 statistical statistical JJ cord-027201-owzhv0xy 145 5 significance significance NN cord-027201-owzhv0xy 145 6 between between IN cord-027201-owzhv0xy 145 7 modeling model VBG cord-027201-owzhv0xy 145 8 time time NN cord-027201-owzhv0xy 145 9 in in IN cord-027201-owzhv0xy 145 10 described describe VBN cord-027201-owzhv0xy 145 11 two two CD cord-027201-owzhv0xy 145 12 methods method NNS cord-027201-owzhv0xy 145 13 . . . cord-027201-owzhv0xy 146 1 Based base VBN cord-027201-owzhv0xy 146 2 on on IN cord-027201-owzhv0xy 146 3 presented present VBN cord-027201-owzhv0xy 146 4 in in IN cord-027201-owzhv0xy 146 5 this this DT cord-027201-owzhv0xy 146 6 paper paper NN cord-027201-owzhv0xy 146 7 results result NNS cord-027201-owzhv0xy 146 8 we -PRON- PRP cord-027201-owzhv0xy 146 9 can can MD cord-027201-owzhv0xy 146 10 conclude conclude VB cord-027201-owzhv0xy 146 11 that that IN cord-027201-owzhv0xy 146 12 when when WRB cord-027201-owzhv0xy 146 13 you -PRON- PRP cord-027201-owzhv0xy 146 14 model model VBP cord-027201-owzhv0xy 146 15 in in IN cord-027201-owzhv0xy 146 16 3D 3d JJ cord-027201-owzhv0xy 146 17 space space NN cord-027201-owzhv0xy 146 18 , , , cord-027201-owzhv0xy 146 19 using use VBG cord-027201-owzhv0xy 146 20 Spherical spherical JJ cord-027201-owzhv0xy 146 21 coordinates coordinate NNS cord-027201-owzhv0xy 146 22 may may MD cord-027201-owzhv0xy 146 23 lead lead VB cord-027201-owzhv0xy 146 24 to to IN cord-027201-owzhv0xy 146 25 a a DT cord-027201-owzhv0xy 146 26 more more RBR cord-027201-owzhv0xy 146 27 efficient efficient JJ cord-027201-owzhv0xy 146 28 implementation implementation NN cord-027201-owzhv0xy 146 29 of of IN cord-027201-owzhv0xy 146 30 the the DT cord-027201-owzhv0xy 146 31 algorithm algorithm NN cord-027201-owzhv0xy 146 32 , , , cord-027201-owzhv0xy 146 33 even even RB cord-027201-owzhv0xy 146 34 when when WRB cord-027201-owzhv0xy 146 35 you -PRON- PRP cord-027201-owzhv0xy 146 36 have have VBP cord-027201-owzhv0xy 146 37 to to TO cord-027201-owzhv0xy 146 38 shift shift VB cord-027201-owzhv0xy 146 39 the the DT cord-027201-owzhv0xy 146 40 center center NN cord-027201-owzhv0xy 146 41 of of IN cord-027201-owzhv0xy 146 42 the the DT cord-027201-owzhv0xy 146 43 coordinate coordinate JJ cord-027201-owzhv0xy 146 44 systems system NNS cord-027201-owzhv0xy 146 45 . . . cord-027201-owzhv0xy 147 1 The the DT cord-027201-owzhv0xy 147 2 solution solution NN cord-027201-owzhv0xy 147 3 when when WRB cord-027201-owzhv0xy 147 4 using use VBG cord-027201-owzhv0xy 147 5 Euclidean euclidean JJ cord-027201-owzhv0xy 147 6 distance distance NN cord-027201-owzhv0xy 147 7 in in IN cord-027201-owzhv0xy 147 8 the the DT cord-027201-owzhv0xy 147 9 Cartesian cartesian JJ cord-027201-owzhv0xy 147 10 coordinate coordinate NN cord-027201-owzhv0xy 147 11 system system NN cord-027201-owzhv0xy 147 12 in in IN cord-027201-owzhv0xy 147 13 implementation implementation NN cord-027201-owzhv0xy 147 14 was be VBD cord-027201-owzhv0xy 147 15 much much RB cord-027201-owzhv0xy 147 16 more more JJR cord-027201-owzhv0xy 147 17 time time NN cord-027201-owzhv0xy 147 18 - - HYPH cord-027201-owzhv0xy 147 19 consuming consume VBG cord-027201-owzhv0xy 147 20 . . . cord-027201-owzhv0xy 148 1 What what WP cord-027201-owzhv0xy 148 2 is be VBZ cord-027201-owzhv0xy 148 3 more more RBR cord-027201-owzhv0xy 148 4 important important JJ cord-027201-owzhv0xy 148 5 -it -it : cord-027201-owzhv0xy 148 6 often often RB cord-027201-owzhv0xy 148 7 does do VBZ cord-027201-owzhv0xy 148 8 not not RB cord-027201-owzhv0xy 148 9 finish finish VB cord-027201-owzhv0xy 148 10 modeling modeling NN cord-027201-owzhv0xy 148 11 process process NN cord-027201-owzhv0xy 148 12 in in IN cord-027201-owzhv0xy 148 13 an an DT cord-027201-owzhv0xy 148 14 acceptable acceptable JJ cord-027201-owzhv0xy 148 15 time time NN cord-027201-owzhv0xy 148 16 ( ( -LRB- cord-027201-owzhv0xy 148 17 sometimes sometimes RB cord-027201-owzhv0xy 148 18 we -PRON- PRP cord-027201-owzhv0xy 148 19 have have VBP cord-027201-owzhv0xy 148 20 to to TO cord-027201-owzhv0xy 148 21 break break VB cord-027201-owzhv0xy 148 22 simulation simulation NN cord-027201-owzhv0xy 148 23 after after IN cord-027201-owzhv0xy 148 24 3 3 CD cord-027201-owzhv0xy 148 25 weeks week NNS cord-027201-owzhv0xy 148 26 of of IN cord-027201-owzhv0xy 148 27 computing compute VBG cord-027201-owzhv0xy 148 28 on on IN cord-027201-owzhv0xy 148 29 a a DT cord-027201-owzhv0xy 148 30 computer computer NN cord-027201-owzhv0xy 148 31 with with IN cord-027201-owzhv0xy 148 32 16 16 CD cord-027201-owzhv0xy 148 33 Gb Gb NNP cord-027201-owzhv0xy 148 34 RAM RAM NNP cord-027201-owzhv0xy 148 35 and and CC cord-027201-owzhv0xy 148 36 i5 i5 NNP cord-027201-owzhv0xy 148 37 processor processor NN cord-027201-owzhv0xy 148 38 ) ) -RRB- cord-027201-owzhv0xy 148 39 , , , cord-027201-owzhv0xy 148 40 if if IN cord-027201-owzhv0xy 148 41 it -PRON- PRP cord-027201-owzhv0xy 148 42 finishes finish VBZ cord-027201-owzhv0xy 148 43 at at RB cord-027201-owzhv0xy 148 44 all all RB cord-027201-owzhv0xy 148 45 ( ( -LRB- cord-027201-owzhv0xy 148 46 do do VBP cord-027201-owzhv0xy 148 47 not not RB cord-027201-owzhv0xy 148 48 got get VBN cord-027201-owzhv0xy 148 49 stuck stick VBN cord-027201-owzhv0xy 148 50 ) ) -RRB- cord-027201-owzhv0xy 148 51 . . . cord-027201-owzhv0xy 149 1 As as IN cord-027201-owzhv0xy 149 2 future future JJ cord-027201-owzhv0xy 149 3 work work NN cord-027201-owzhv0xy 149 4 , , , cord-027201-owzhv0xy 149 5 knowing know VBG cord-027201-owzhv0xy 149 6 that that IN cord-027201-owzhv0xy 149 7 using use VBG cord-027201-owzhv0xy 149 8 a a DT cord-027201-owzhv0xy 149 9 spherical spherical JJ cord-027201-owzhv0xy 149 10 coordinate coordinate JJ cord-027201-owzhv0xy 149 11 system system NN cord-027201-owzhv0xy 149 12 is be VBZ cord-027201-owzhv0xy 149 13 helpful helpful JJ cord-027201-owzhv0xy 149 14 we -PRON- PRP cord-027201-owzhv0xy 149 15 want want VBP cord-027201-owzhv0xy 149 16 to to TO cord-027201-owzhv0xy 149 17 examine examine VB cord-027201-owzhv0xy 149 18 the the DT cord-027201-owzhv0xy 149 19 effectiveness effectiveness NN cord-027201-owzhv0xy 149 20 of of IN cord-027201-owzhv0xy 149 21 quaternion quaternion NN cord-027201-owzhv0xy 149 22 - - HYPH cord-027201-owzhv0xy 149 23 based base VBN cord-027201-owzhv0xy 149 24 implementation implementation NN cord-027201-owzhv0xy 149 25 as as IN cord-027201-owzhv0xy 149 26 a a DT cord-027201-owzhv0xy 149 27 way way NN cord-027201-owzhv0xy 149 28 to to TO cord-027201-owzhv0xy 149 29 represent represent VB cord-027201-owzhv0xy 149 30 coordinates coordinate NNS cord-027201-owzhv0xy 149 31 in in IN cord-027201-owzhv0xy 149 32 3D 3d JJ cord-027201-owzhv0xy 149 33 space space NN cord-027201-owzhv0xy 149 34 . . . cord-027201-owzhv0xy 150 1 We -PRON- PRP cord-027201-owzhv0xy 150 2 also also RB cord-027201-owzhv0xy 150 3 want want VBP cord-027201-owzhv0xy 150 4 to to TO cord-027201-owzhv0xy 150 5 check check VB cord-027201-owzhv0xy 150 6 in in IN cord-027201-owzhv0xy 150 7 a a DT cord-027201-owzhv0xy 150 8 more more RBR cord-027201-owzhv0xy 150 9 detailed detailed JJ cord-027201-owzhv0xy 150 10 way way NN cord-027201-owzhv0xy 150 11 , , , cord-027201-owzhv0xy 150 12 what what WP cord-027201-owzhv0xy 150 13 has have VBZ cord-027201-owzhv0xy 150 14 an an DT cord-027201-owzhv0xy 150 15 impact impact NN cord-027201-owzhv0xy 150 16 : : : cord-027201-owzhv0xy 150 17 only only RB cord-027201-owzhv0xy 150 18 changing change VBG cord-027201-owzhv0xy 150 19 the the DT cord-027201-owzhv0xy 150 20 center center NN cord-027201-owzhv0xy 150 21 of of IN cord-027201-owzhv0xy 150 22 the the DT cord-027201-owzhv0xy 150 23 coordinate coordinate JJ cord-027201-owzhv0xy 150 24 system system NN cord-027201-owzhv0xy 150 25 , , , cord-027201-owzhv0xy 150 26 only only RB cord-027201-owzhv0xy 150 27 changing change VBG cord-027201-owzhv0xy 150 28 the the DT cord-027201-owzhv0xy 150 29 way way NN cord-027201-owzhv0xy 150 30 of of IN cord-027201-owzhv0xy 150 31 point point NN cord-027201-owzhv0xy 150 32 representation representation NN cord-027201-owzhv0xy 150 33 -or -or : cord-027201-owzhv0xy 150 34 both both DT cord-027201-owzhv0xy 150 35 . . . cord-027201-owzhv0xy 151 1 Because because IN cord-027201-owzhv0xy 151 2 it -PRON- PRP cord-027201-owzhv0xy 151 3 is be VBZ cord-027201-owzhv0xy 151 4 not not RB cord-027201-owzhv0xy 151 5 the the DT cord-027201-owzhv0xy 151 6 first first JJ cord-027201-owzhv0xy 151 7 time time NN cord-027201-owzhv0xy 151 8 when when WRB cord-027201-owzhv0xy 151 9 we -PRON- PRP cord-027201-owzhv0xy 151 10 noticed notice VBD cord-027201-owzhv0xy 151 11 significant significant JJ cord-027201-owzhv0xy 151 12 change change NN cord-027201-owzhv0xy 151 13 ( ( -LRB- cord-027201-owzhv0xy 151 14 in in IN cord-027201-owzhv0xy 151 15 plus plus NN cord-027201-owzhv0xy 151 16 ) ) -RRB- cord-027201-owzhv0xy 151 17 after after IN cord-027201-owzhv0xy 151 18 using use VBG cord-027201-owzhv0xy 151 19 Spherical Spherical NNP cord-027201-owzhv0xy 151 20 ( ( -LRB- cord-027201-owzhv0xy 151 21 or or CC cord-027201-owzhv0xy 151 22 hyperspherical hyperspherical JJ cord-027201-owzhv0xy 151 23 -in -in : cord-027201-owzhv0xy 151 24 more more JJR cord-027201-owzhv0xy 151 25 dimensions dimension NNS cord-027201-owzhv0xy 151 26 ) ) -RRB- cord-027201-owzhv0xy 151 27 Coordinates coordinate VBZ cord-027201-owzhv0xy 151 28 instead instead RB cord-027201-owzhv0xy 151 29 of of IN cord-027201-owzhv0xy 151 30 the the DT cord-027201-owzhv0xy 151 31 Cartesian cartesian JJ cord-027201-owzhv0xy 151 32 ones one NNS cord-027201-owzhv0xy 151 33 , , , cord-027201-owzhv0xy 151 34 we -PRON- PRP cord-027201-owzhv0xy 151 35 plan plan VBP cord-027201-owzhv0xy 151 36 ( ( -LRB- cord-027201-owzhv0xy 151 37 after after IN cord-027201-owzhv0xy 151 38 finishing finish VBG cord-027201-owzhv0xy 151 39 actual actual JJ cord-027201-owzhv0xy 151 40 projects project NNS cord-027201-owzhv0xy 151 41 with with IN cord-027201-owzhv0xy 151 42 deadlines deadline NNS cord-027201-owzhv0xy 151 43 ) ) -RRB- cord-027201-owzhv0xy 151 44 design design NN cord-027201-owzhv0xy 151 45 and and CC cord-027201-owzhv0xy 151 46 conduct conduct VB cord-027201-owzhv0xy 151 47 a a DT cord-027201-owzhv0xy 151 48 separate separate JJ cord-027201-owzhv0xy 151 49 experiment experiment NN cord-027201-owzhv0xy 151 50 . . . cord-027201-owzhv0xy 152 1 We -PRON- PRP cord-027201-owzhv0xy 152 2 want want VBP cord-027201-owzhv0xy 152 3 to to TO cord-027201-owzhv0xy 152 4 investigate investigate VB cord-027201-owzhv0xy 152 5 in in IN cord-027201-owzhv0xy 152 6 a a DT cord-027201-owzhv0xy 152 7 more more RBR cord-027201-owzhv0xy 152 8 methodological methodological JJ cord-027201-owzhv0xy 152 9 and and CC cord-027201-owzhv0xy 152 10 ordered order VBN cord-027201-owzhv0xy 152 11 way way NN cord-027201-owzhv0xy 152 12 to to TO cord-027201-owzhv0xy 152 13 answer answer VB cord-027201-owzhv0xy 152 14 the the DT cord-027201-owzhv0xy 152 15 question question NN cord-027201-owzhv0xy 152 16 : : : cord-027201-owzhv0xy 152 17 why why WRB cord-027201-owzhv0xy 152 18 Spherical spherical JJ cord-027201-owzhv0xy 152 19 coordinates coordinate NNS cord-027201-owzhv0xy 152 20 give give VBP cord-027201-owzhv0xy 152 21 better well JJR cord-027201-owzhv0xy 152 22 results result NNS cord-027201-owzhv0xy 152 23 in in IN cord-027201-owzhv0xy 152 24 computational computational JJ cord-027201-owzhv0xy 152 25 implementations implementation NNS cord-027201-owzhv0xy 152 26 ? ? . cord-027201-owzhv0xy 153 1 Our -PRON- PRP$ cord-027201-owzhv0xy 153 2 case case NN cord-027201-owzhv0xy 153 3 study study NN cord-027201-owzhv0xy 153 4 also also RB cord-027201-owzhv0xy 153 5 shows show VBZ cord-027201-owzhv0xy 153 6 that that IN cord-027201-owzhv0xy 153 7 it -PRON- PRP cord-027201-owzhv0xy 153 8 is be VBZ cord-027201-owzhv0xy 153 9 possible possible JJ cord-027201-owzhv0xy 153 10 that that IN cord-027201-owzhv0xy 153 11 geometrical geometrical JJ cord-027201-owzhv0xy 153 12 and and CC cord-027201-owzhv0xy 153 13 visual visual JJ cord-027201-owzhv0xy 153 14 thinking thinking NN cord-027201-owzhv0xy 153 15 while while IN cord-027201-owzhv0xy 153 16 modeling model VBG cord-027201-owzhv0xy 153 17 in in IN cord-027201-owzhv0xy 153 18 3D 3d JJ cord-027201-owzhv0xy 153 19 space space NN cord-027201-owzhv0xy 153 20 can can MD cord-027201-owzhv0xy 153 21 be be VB cord-027201-owzhv0xy 153 22 helpful helpful JJ cord-027201-owzhv0xy 153 23 . . . cord-027201-owzhv0xy 154 1 With with IN cord-027201-owzhv0xy 154 2 the the DT cord-027201-owzhv0xy 154 3 " " `` cord-027201-owzhv0xy 154 4 pure pure JJ cord-027201-owzhv0xy 154 5 algebraic algebraic NN cord-027201-owzhv0xy 154 6 " " '' cord-027201-owzhv0xy 154 7 thinking thinking NN cord-027201-owzhv0xy 154 8 ( ( -LRB- cord-027201-owzhv0xy 154 9 based base VBN cord-027201-owzhv0xy 154 10 on on IN cord-027201-owzhv0xy 154 11 the the DT cord-027201-owzhv0xy 154 12 calculation calculation NN cord-027201-owzhv0xy 154 13 on on IN cord-027201-owzhv0xy 154 14 coordinates coordinate NNS cord-027201-owzhv0xy 154 15 ) ) -RRB- cord-027201-owzhv0xy 154 16 finding find VBG cord-027201-owzhv0xy 154 17 the the DT cord-027201-owzhv0xy 154 18 idea idea NN cord-027201-owzhv0xy 154 19 -to -to ADD cord-027201-owzhv0xy 154 20 search search NN cord-027201-owzhv0xy 154 21 in in IN cord-027201-owzhv0xy 154 22 the the DT cord-027201-owzhv0xy 154 23 neighborhood neighborhood NN cord-027201-owzhv0xy 154 24 , , , cord-027201-owzhv0xy 154 25 shifting shift VBG cord-027201-owzhv0xy 154 26 the the DT cord-027201-owzhv0xy 154 27 center center NN cord-027201-owzhv0xy 154 28 of of IN cord-027201-owzhv0xy 154 29 the the DT cord-027201-owzhv0xy 154 30 coordinate coordinate JJ cord-027201-owzhv0xy 154 31 system system NN cord-027201-owzhv0xy 154 32 and and CC cord-027201-owzhv0xy 154 33 next next JJ cord-027201-owzhv0xy 154 34 using use VBG cord-027201-owzhv0xy 154 35 direction direction NN cord-027201-owzhv0xy 154 36 ( ( -LRB- cord-027201-owzhv0xy 154 37 angles angle NNS cord-027201-owzhv0xy 154 38 ) ) -RRB- cord-027201-owzhv0xy 154 39 and and CC cord-027201-owzhv0xy 154 40 fixed fix VBN cord-027201-owzhv0xy 154 41 distance distance NN cord-027201-owzhv0xy 154 42 -would -would MD cord-027201-owzhv0xy 154 43 be be VB cord-027201-owzhv0xy 154 44 more more RBR cord-027201-owzhv0xy 154 45 difficult difficult JJ cord-027201-owzhv0xy 154 46 ( ( -LRB- cord-027201-owzhv0xy 154 47 if if IN cord-027201-owzhv0xy 154 48 even even RB cord-027201-owzhv0xy 154 49 possible possible JJ cord-027201-owzhv0xy 154 50 ) ) -RRB- cord-027201-owzhv0xy 154 51 . . . cord-027201-owzhv0xy 155 1 Synthetic synthetic JJ cord-027201-owzhv0xy 155 2 Cell cell NN cord-027201-owzhv0xy 155 3 Project Project NNP cord-027201-owzhv0xy 156 1 The the DT cord-027201-owzhv0xy 156 2 genome genome NN cord-027201-owzhv0xy 156 3 - - HYPH cord-027201-owzhv0xy 156 4 seeing see VBG cord-027201-owzhv0xy 156 5 it -PRON- PRP cord-027201-owzhv0xy 156 6 clearly clearly RB cord-027201-owzhv0xy 156 7 now now RB cord-027201-owzhv0xy 156 8 Maternal maternal JJ cord-027201-owzhv0xy 156 9 prenatal prenatal JJ cord-027201-owzhv0xy 156 10 stress stress NN cord-027201-owzhv0xy 156 11 and and CC cord-027201-owzhv0xy 156 12 the the DT cord-027201-owzhv0xy 156 13 developmental developmental JJ cord-027201-owzhv0xy 156 14 origins origin NNS cord-027201-owzhv0xy 156 15 of of IN cord-027201-owzhv0xy 156 16 mental mental JJ cord-027201-owzhv0xy 156 17 health health NN cord-027201-owzhv0xy 156 18 . . . cord-027201-owzhv0xy 157 1 The the DT cord-027201-owzhv0xy 157 2 Epigenome Epigenome NNP cord-027201-owzhv0xy 157 3 and and CC cord-027201-owzhv0xy 157 4 Developmental Developmental NNP cord-027201-owzhv0xy 157 5 Origins Origins NNPS cord-027201-owzhv0xy 157 6 of of IN cord-027201-owzhv0xy 157 7 Health Health NNP cord-027201-owzhv0xy 157 8 and and CC cord-027201-owzhv0xy 157 9 Disease Disease NNP cord-027201-owzhv0xy 157 10 Multiple multiple JJ cord-027201-owzhv0xy 157 11 aspects aspect NNS cord-027201-owzhv0xy 157 12 of of IN cord-027201-owzhv0xy 157 13 gene gene NN cord-027201-owzhv0xy 157 14 dysregulation dysregulation NN cord-027201-owzhv0xy 157 15 in in IN cord-027201-owzhv0xy 157 16 Huntington Huntington NNP cord-027201-owzhv0xy 157 17 's 's POS cord-027201-owzhv0xy 157 18 disease disease NN cord-027201-owzhv0xy 157 19 . . . cord-027201-owzhv0xy 158 1 Front front NN cord-027201-owzhv0xy 158 2 . . . cord-027201-owzhv0xy 159 1 Neurol Neurol NNP cord-027201-owzhv0xy 159 2 Nucleosome Nucleosome NNP cord-027201-owzhv0xy 159 3 positioning positioning NN cord-027201-owzhv0xy 159 4 in in IN cord-027201-owzhv0xy 159 5 saccharomyces saccharomyce NNS cord-027201-owzhv0xy 159 6 cerevisiae cerevisiae NNS cord-027201-owzhv0xy 159 7 Chromatin Chromatin NNP cord-027201-owzhv0xy 159 8 condensation condensation NN cord-027201-owzhv0xy 159 9 modulates modulate VBZ cord-027201-owzhv0xy 159 10 access access NN cord-027201-owzhv0xy 159 11 and and CC cord-027201-owzhv0xy 159 12 binding binding NN cord-027201-owzhv0xy 159 13 of of IN cord-027201-owzhv0xy 159 14 nuclear nuclear JJ cord-027201-owzhv0xy 159 15 proteins protein NNS cord-027201-owzhv0xy 159 16 Activation Activation NNP cord-027201-owzhv0xy 159 17 of of IN cord-027201-owzhv0xy 159 18 DNA dna NN cord-027201-owzhv0xy 159 19 damage damage NN cord-027201-owzhv0xy 159 20 response response NN cord-027201-owzhv0xy 159 21 signaling signal VBG cord-027201-owzhv0xy 159 22 by by IN cord-027201-owzhv0xy 159 23 condensed condense VBN cord-027201-owzhv0xy 159 24 chromatin chromatin NN cord-027201-owzhv0xy 159 25 Nucleoplasmin Nucleoplasmin NNP cord-027201-owzhv0xy 159 26 regulates regulate VBZ cord-027201-owzhv0xy 159 27 chromatin chromatin NN cord-027201-owzhv0xy 159 28 condensation condensation NN cord-027201-owzhv0xy 159 29 during during IN cord-027201-owzhv0xy 159 30 apoptosis apoptosis NN cord-027201-owzhv0xy 159 31 Chromosome chromosome NN cord-027201-owzhv0xy 159 32 condensation condensation NN cord-027201-owzhv0xy 159 33 and and CC cord-027201-owzhv0xy 159 34 decondensation decondensation NN cord-027201-owzhv0xy 159 35 during during IN cord-027201-owzhv0xy 159 36 mitosis mitosis NN cord-027201-owzhv0xy 159 37 Chromosome Chromosome NNP cord-027201-owzhv0xy 159 38 territories territory NNS cord-027201-owzhv0xy 160 1 How how WRB cord-027201-owzhv0xy 160 2 do do VBP cord-027201-owzhv0xy 160 3 chromosome chromosome NN cord-027201-owzhv0xy 160 4 territory territory NN cord-027201-owzhv0xy 160 5 dynamics dynamic NNS cord-027201-owzhv0xy 160 6 affect affect VBP cord-027201-owzhv0xy 160 7 gene gene NN cord-027201-owzhv0xy 160 8 redistribution redistribution NN cord-027201-owzhv0xy 160 9 ? ? . cord-027201-owzhv0xy 161 1 https://www https://www . cord-027201-owzhv0xy 161 2 . . . cord-027201-owzhv0xy 162 1 mechanobio.info/genome-regulation/how-do-chromosome-territory-dynamicsaffect-gene-redistribution mechanobio.info/genome-regulation/how-do-chromosome-territory-dynamicsaffect-gene-redistribution NNP cord-027201-owzhv0xy 163 1 Chromosome chromosome NN cord-027201-owzhv0xy 163 2 territory territory NN cord-027201-owzhv0xy 163 3 formation formation NN cord-027201-owzhv0xy 163 4 attenuates attenuate VBZ cord-027201-owzhv0xy 163 5 the the DT cord-027201-owzhv0xy 163 6 translocation translocation NN cord-027201-owzhv0xy 163 7 potential potential NN cord-027201-owzhv0xy 163 8 of of IN cord-027201-owzhv0xy 163 9 cells cell NNS cord-027201-owzhv0xy 163 10 . . . cord-027201-owzhv0xy 164 1 eLife eLife NNP cord-027201-owzhv0xy 164 2 Chromosome Chromosome NNP cord-027201-owzhv0xy 164 3 territories territory NNS cord-027201-owzhv0xy 164 4 and and CC cord-027201-owzhv0xy 164 5 the the DT cord-027201-owzhv0xy 164 6 global global JJ cord-027201-owzhv0xy 164 7 regulation regulation NN cord-027201-owzhv0xy 164 8 of of IN cord-027201-owzhv0xy 164 9 the the DT cord-027201-owzhv0xy 164 10 genome genome NN cord-027201-owzhv0xy 164 11 Chromatin Chromatin NNP cord-027201-owzhv0xy 164 12 spheres sphere NNS cord-027201-owzhv0xy 164 13 and and CC cord-027201-owzhv0xy 164 14 the the DT cord-027201-owzhv0xy 164 15 interchromatin interchromatin NNP cord-027201-owzhv0xy 164 16 compartment compartment NN cord-027201-owzhv0xy 164 17 form form NN cord-027201-owzhv0xy 164 18 structurally structurally RB cord-027201-owzhv0xy 164 19 defined define VBN cord-027201-owzhv0xy 164 20 and and CC cord-027201-owzhv0xy 164 21 functionally functionally RB cord-027201-owzhv0xy 164 22 interacting interact VBG cord-027201-owzhv0xy 164 23 nuclear nuclear JJ cord-027201-owzhv0xy 164 24 networks network NNS cord-027201-owzhv0xy 164 25 Inheritance Inheritance NNP cord-027201-owzhv0xy 164 26 of of IN cord-027201-owzhv0xy 164 27 gene gene NN cord-027201-owzhv0xy 164 28 density density NN cord-027201-owzhv0xy 164 29 - - HYPH cord-027201-owzhv0xy 164 30 related relate VBN cord-027201-owzhv0xy 164 31 higher high JJR cord-027201-owzhv0xy 164 32 order order NN cord-027201-owzhv0xy 164 33 chromatin chromatin NN cord-027201-owzhv0xy 164 34 arrangements arrangement NNS cord-027201-owzhv0xy 164 35 in in IN cord-027201-owzhv0xy 164 36 normal normal JJ cord-027201-owzhv0xy 164 37 and and CC cord-027201-owzhv0xy 164 38 tumor tumor NN cord-027201-owzhv0xy 164 39 cell cell NN cord-027201-owzhv0xy 164 40 nuclei nucleus NNS cord-027201-owzhv0xy 164 41 Chromosome chromosome NN cord-027201-owzhv0xy 164 42 territories territory NNS cord-027201-owzhv0xy 164 43 , , , cord-027201-owzhv0xy 164 44 nuclear nuclear JJ cord-027201-owzhv0xy 164 45 architecture architecture NN cord-027201-owzhv0xy 164 46 and and CC cord-027201-owzhv0xy 164 47 gene gene NN cord-027201-owzhv0xy 164 48 regulation regulation NN cord-027201-owzhv0xy 164 49 in in IN cord-027201-owzhv0xy 164 50 mammalian mammalian JJ cord-027201-owzhv0xy 164 51 cells cell NNS cord-027201-owzhv0xy 164 52 Nuclear nuclear JJ cord-027201-owzhv0xy 164 53 organization organization NN cord-027201-owzhv0xy 164 54 of of IN cord-027201-owzhv0xy 164 55 the the DT cord-027201-owzhv0xy 164 56 genome genome NN cord-027201-owzhv0xy 164 57 and and CC cord-027201-owzhv0xy 164 58 the the DT cord-027201-owzhv0xy 164 59 potential potential NN cord-027201-owzhv0xy 164 60 for for IN cord-027201-owzhv0xy 164 61 gene gene NN cord-027201-owzhv0xy 164 62 regulation regulation NN cord-027201-owzhv0xy 164 63 Fluorescence Fluorescence NNP cord-027201-owzhv0xy 164 64 in in IN cord-027201-owzhv0xy 164 65 situ situ NN cord-027201-owzhv0xy 164 66 hybridization hybridization NN cord-027201-owzhv0xy 164 67 with with IN cord-027201-owzhv0xy 164 68 human human JJ cord-027201-owzhv0xy 164 69 chromosome chromosome NN cord-027201-owzhv0xy 164 70 - - HYPH cord-027201-owzhv0xy 164 71 specific specific JJ cord-027201-owzhv0xy 164 72 libraries library NNS cord-027201-owzhv0xy 164 73 : : : cord-027201-owzhv0xy 164 74 detection detection NN cord-027201-owzhv0xy 164 75 of of IN cord-027201-owzhv0xy 164 76 trisomy trisomy NN cord-027201-owzhv0xy 164 77 21 21 CD cord-027201-owzhv0xy 164 78 and and CC cord-027201-owzhv0xy 164 79 translocations translocation NNS cord-027201-owzhv0xy 164 80 of of IN cord-027201-owzhv0xy 164 81 chromosome chromosome NN cord-027201-owzhv0xy 164 82 4 4 CD cord-027201-owzhv0xy 164 83 Spatial spatial JJ cord-027201-owzhv0xy 164 84 organization organization NN cord-027201-owzhv0xy 164 85 of of IN cord-027201-owzhv0xy 164 86 the the DT cord-027201-owzhv0xy 164 87 mouse mouse NN cord-027201-owzhv0xy 164 88 genome genome NN cord-027201-owzhv0xy 164 89 and and CC cord-027201-owzhv0xy 164 90 its -PRON- PRP$ cord-027201-owzhv0xy 164 91 role role NN cord-027201-owzhv0xy 164 92 in in IN cord-027201-owzhv0xy 164 93 recurrent recurrent JJ cord-027201-owzhv0xy 164 94 chromosomal chromosomal JJ cord-027201-owzhv0xy 164 95 translocations translocation NNS cord-027201-owzhv0xy 164 96 Cell cell NN cord-027201-owzhv0xy 164 97 biology biology NN cord-027201-owzhv0xy 164 98 -chromosome -chromosome WDT cord-027201-owzhv0xy 164 99 territories territory NNS cord-027201-owzhv0xy 164 100 Chromosome Chromosome NNP cord-027201-owzhv0xy 164 101 territories territory NNS cord-027201-owzhv0xy 165 1 -a -a : cord-027201-owzhv0xy 166 1 functional functional JJ cord-027201-owzhv0xy 166 2 nuclear nuclear JJ cord-027201-owzhv0xy 166 3 landscape landscape NN cord-027201-owzhv0xy 166 4 Chromosome chromosome NN cord-027201-owzhv0xy 166 5 territories territory NNS cord-027201-owzhv0xy 166 6 : : : cord-027201-owzhv0xy 166 7 the the DT cord-027201-owzhv0xy 166 8 arrangement arrangement NN cord-027201-owzhv0xy 166 9 of of IN cord-027201-owzhv0xy 166 10 chromosomes chromosome NNS cord-027201-owzhv0xy 166 11 in in IN cord-027201-owzhv0xy 166 12 the the DT cord-027201-owzhv0xy 166 13 nucleus nucleus NN cord-027201-owzhv0xy 166 14 Chromosome Chromosome NNP cord-027201-owzhv0xy 166 15 territory territory NN cord-027201-owzhv0xy 166 16 modeler modeler NN cord-027201-owzhv0xy 166 17 and and CC cord-027201-owzhv0xy 166 18 viewer viewer VB cord-027201-owzhv0xy 166 19 Spherical spherical JJ cord-027201-owzhv0xy 166 20 coordinates coordinate NNS cord-027201-owzhv0xy 166 21 . . . cord-027201-owzhv0xy 167 1 From from IN cord-027201-owzhv0xy 167 2 math math NN cord-027201-owzhv0xy 167 3 insight insight NN cord-027201-owzhv0xy 167 4 Cartesian Cartesian NNP cord-027201-owzhv0xy 167 5 , , , cord-027201-owzhv0xy 167 6 polar polar JJ cord-027201-owzhv0xy 167 7 , , , cord-027201-owzhv0xy 167 8 cylindrical cylindrical JJ cord-027201-owzhv0xy 167 9 , , , cord-027201-owzhv0xy 167 10 and and CC cord-027201-owzhv0xy 167 11 spherical spherical JJ cord-027201-owzhv0xy 167 12 coordinates coordinate NNS