id	sid	tid	token	lemma	pos
cord-024061-gxv8y146	1	1	key	key	NN
cord-024061-gxv8y146	1	2	:	:	:
cord-024061-gxv8y146	2	1	cord-024061-gxv8y146	cord-024061-gxv8y146	NNP
cord-024061-gxv8y146	3	1	authors	author	NNS
cord-024061-gxv8y146	3	2	:	:	:
cord-024061-gxv8y146	3	3	Alkhamis	Alkhamis	NNP
cord-024061-gxv8y146	3	4	,	,	,
cord-024061-gxv8y146	3	5	Moh	Moh	NNP
cord-024061-gxv8y146	3	6	A.	a.	NN
cord-024061-gxv8y146	3	7	;	;	:
cord-024061-gxv8y146	3	8	Li	Li	NNP
cord-024061-gxv8y146	3	9	,	,	,
cord-024061-gxv8y146	3	10	Chong	Chong	NNP
cord-024061-gxv8y146	3	11	;	;	:
cord-024061-gxv8y146	3	12	Torremorell	Torremorell	NNP
cord-024061-gxv8y146	3	13	,	,	,
cord-024061-gxv8y146	3	14	Montserrat	Montserrat	NNP
cord-024061-gxv8y146	3	15	title	title	NN
cord-024061-gxv8y146	3	16	:	:	:
cord-024061-gxv8y146	3	17	Animal	Animal	NNP
cord-024061-gxv8y146	3	18	Disease	Disease	NNP
cord-024061-gxv8y146	3	19	Surveillance	surveillance	NN
cord-024061-gxv8y146	3	20	in	in	IN
cord-024061-gxv8y146	3	21	the	the	DT
cord-024061-gxv8y146	3	22	21st	21st	JJ
cord-024061-gxv8y146	3	23	Century	century	NN
cord-024061-gxv8y146	3	24	:	:	:
cord-024061-gxv8y146	4	1	Applications	application	NNS
cord-024061-gxv8y146	4	2	and	and	CC
cord-024061-gxv8y146	4	3	Robustness	Robustness	NNP
cord-024061-gxv8y146	4	4	of	of	IN
cord-024061-gxv8y146	4	5	Phylodynamic	Phylodynamic	NNP
cord-024061-gxv8y146	4	6	Methods	Methods	NNPS
cord-024061-gxv8y146	4	7	in	in	IN
cord-024061-gxv8y146	4	8	Recent	Recent	NNP
cord-024061-gxv8y146	4	9	U.S.	U.S.	NNP
cord-024061-gxv8y146	4	10	Human	Human	NNP
cord-024061-gxv8y146	4	11	-	-	HYPH
cord-024061-gxv8y146	4	12	Like	like	JJ
cord-024061-gxv8y146	4	13	H3	H3	NNP
cord-024061-gxv8y146	4	14	Swine	Swine	NNP
cord-024061-gxv8y146	4	15	Influenza	Influenza	NNP
cord-024061-gxv8y146	4	16	Outbreaks	outbreak	NNS
cord-024061-gxv8y146	4	17	date	date	NN
cord-024061-gxv8y146	4	18	:	:	:
cord-024061-gxv8y146	4	19	2020	2020	CD
cord-024061-gxv8y146	4	20	-	-	HYPH
cord-024061-gxv8y146	4	21	04	04	CD
cord-024061-gxv8y146	4	22	-	-	SYM
cord-024061-gxv8y146	4	23	21	21	CD
cord-024061-gxv8y146	4	24	journal	journal	NN
cord-024061-gxv8y146	4	25	:	:	:
cord-024061-gxv8y146	5	1	Front	front	JJ
cord-024061-gxv8y146	5	2	Vet	Vet	NNP
cord-024061-gxv8y146	5	3	Sci	Sci	NNP
cord-024061-gxv8y146	5	4	DOI	DOI	NNP
cord-024061-gxv8y146	6	1	:	:	:
cord-024061-gxv8y146	6	2	10.3389	10.3389	CD
cord-024061-gxv8y146	6	3	/	/	SYM
cord-024061-gxv8y146	6	4	fvets.2020.00176	fvets.2020.00176	CD
cord-024061-gxv8y146	6	5	sha	sha	NNP
cord-024061-gxv8y146	6	6	:	:	:
cord-024061-gxv8y146	6	7	80fbd7407b778e7aa4b5304e62ede135d2e8e59a	80fbd7407b778e7aa4b5304e62ede135d2e8e59a	CD
cord-024061-gxv8y146	6	8	doc_id	doc_id	CD
cord-024061-gxv8y146	6	9	:	:	:
cord-024061-gxv8y146	7	1	24061	24061	CD
cord-024061-gxv8y146	7	2	cord_uid	cord_uid	NNS
cord-024061-gxv8y146	7	3	:	:	:
cord-024061-gxv8y146	8	1	gxv8y146	gxv8y146	NNP
cord-024061-gxv8y146	8	2	Emerging	Emerging	NNP
cord-024061-gxv8y146	8	3	and	and	CC
cord-024061-gxv8y146	8	4	endemic	endemic	JJ
cord-024061-gxv8y146	8	5	animal	animal	NN
cord-024061-gxv8y146	8	6	viral	viral	JJ
cord-024061-gxv8y146	8	7	diseases	disease	NNS
cord-024061-gxv8y146	8	8	continue	continue	VBP
cord-024061-gxv8y146	8	9	to	to	TO
cord-024061-gxv8y146	8	10	impose	impose	VB
cord-024061-gxv8y146	8	11	substantial	substantial	JJ
cord-024061-gxv8y146	8	12	impacts	impact	NNS
cord-024061-gxv8y146	8	13	on	on	IN
cord-024061-gxv8y146	8	14	animal	animal	NN
cord-024061-gxv8y146	8	15	and	and	CC
cord-024061-gxv8y146	8	16	human	human	JJ
cord-024061-gxv8y146	8	17	health	health	NN
cord-024061-gxv8y146	8	18	.	.	.
cord-024061-gxv8y146	9	1	Most	most	RBS
cord-024061-gxv8y146	9	2	current	current	JJ
cord-024061-gxv8y146	9	3	and	and	CC
cord-024061-gxv8y146	9	4	past	past	JJ
cord-024061-gxv8y146	9	5	molecular	molecular	JJ
cord-024061-gxv8y146	9	6	surveillance	surveillance	NN
cord-024061-gxv8y146	9	7	studies	study	NNS
cord-024061-gxv8y146	9	8	of	of	IN
cord-024061-gxv8y146	9	9	animal	animal	NN
cord-024061-gxv8y146	9	10	diseases	disease	NNS
cord-024061-gxv8y146	9	11	investigated	investigate	VBD
cord-024061-gxv8y146	9	12	spatio	spatio	JJ
cord-024061-gxv8y146	9	13	-	-	HYPH
cord-024061-gxv8y146	9	14	temporal	temporal	JJ
cord-024061-gxv8y146	9	15	and	and	CC
cord-024061-gxv8y146	9	16	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	9	17	dynamics	dynamic	NNS
cord-024061-gxv8y146	9	18	of	of	IN
cord-024061-gxv8y146	9	19	the	the	DT
cord-024061-gxv8y146	9	20	viruses	virus	NNS
cord-024061-gxv8y146	9	21	in	in	IN
cord-024061-gxv8y146	9	22	a	a	DT
cord-024061-gxv8y146	9	23	disjointed	disjointed	JJ
cord-024061-gxv8y146	9	24	analytical	analytical	JJ
cord-024061-gxv8y146	9	25	framework	framework	NN
cord-024061-gxv8y146	9	26	,	,	,
cord-024061-gxv8y146	9	27	ignoring	ignore	VBG
cord-024061-gxv8y146	9	28	many	many	JJ
cord-024061-gxv8y146	9	29	uncertainties	uncertainty	NNS
cord-024061-gxv8y146	9	30	and	and	CC
cord-024061-gxv8y146	9	31	made	make	VBD
cord-024061-gxv8y146	9	32	joint	joint	JJ
cord-024061-gxv8y146	9	33	conclusions	conclusion	NNS
cord-024061-gxv8y146	9	34	from	from	IN
cord-024061-gxv8y146	9	35	both	both	DT
cord-024061-gxv8y146	9	36	analytical	analytical	JJ
cord-024061-gxv8y146	9	37	approaches	approach	NNS
cord-024061-gxv8y146	9	38	.	.	.
cord-024061-gxv8y146	10	1	Phylodynamic	Phylodynamic	NNP
cord-024061-gxv8y146	10	2	methods	method	NNS
cord-024061-gxv8y146	10	3	offer	offer	VBP
cord-024061-gxv8y146	10	4	a	a	DT
cord-024061-gxv8y146	10	5	uniquely	uniquely	RB
cord-024061-gxv8y146	10	6	integrated	integrate	VBN
cord-024061-gxv8y146	10	7	platform	platform	NN
cord-024061-gxv8y146	10	8	capable	capable	JJ
cord-024061-gxv8y146	10	9	of	of	IN
cord-024061-gxv8y146	10	10	inferring	infer	VBG
cord-024061-gxv8y146	10	11	complex	complex	JJ
cord-024061-gxv8y146	10	12	epidemiological	epidemiological	JJ
cord-024061-gxv8y146	10	13	and	and	CC
cord-024061-gxv8y146	10	14	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	10	15	processes	process	NNS
cord-024061-gxv8y146	10	16	from	from	IN
cord-024061-gxv8y146	10	17	the	the	DT
cord-024061-gxv8y146	10	18	phylogeny	phylogeny	NN
cord-024061-gxv8y146	10	19	of	of	IN
cord-024061-gxv8y146	10	20	viruses	virus	NNS
cord-024061-gxv8y146	10	21	in	in	IN
cord-024061-gxv8y146	10	22	populations	population	NNS
cord-024061-gxv8y146	10	23	using	use	VBG
cord-024061-gxv8y146	10	24	a	a	DT
cord-024061-gxv8y146	10	25	single	single	JJ
cord-024061-gxv8y146	10	26	Bayesian	bayesian	JJ
cord-024061-gxv8y146	10	27	statistical	statistical	JJ
cord-024061-gxv8y146	10	28	framework	framework	NN
cord-024061-gxv8y146	10	29	.	.	.
cord-024061-gxv8y146	11	1	In	in	IN
cord-024061-gxv8y146	11	2	this	this	DT
cord-024061-gxv8y146	11	3	study	study	NN
cord-024061-gxv8y146	11	4	,	,	,
cord-024061-gxv8y146	11	5	we	-PRON-	PRP
cord-024061-gxv8y146	11	6	reviewed	review	VBD
cord-024061-gxv8y146	11	7	and	and	CC
cord-024061-gxv8y146	11	8	outlined	outline	VBD
cord-024061-gxv8y146	11	9	basic	basic	JJ
cord-024061-gxv8y146	11	10	concepts	concept	NNS
cord-024061-gxv8y146	11	11	and	and	CC
cord-024061-gxv8y146	11	12	aspects	aspect	NNS
cord-024061-gxv8y146	11	13	of	of	IN
cord-024061-gxv8y146	11	14	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	11	15	methods	method	NNS
cord-024061-gxv8y146	11	16	and	and	CC
cord-024061-gxv8y146	11	17	attempted	attempt	VBD
cord-024061-gxv8y146	11	18	to	to	TO
cord-024061-gxv8y146	11	19	summarize	summarize	VB
cord-024061-gxv8y146	11	20	essential	essential	JJ
cord-024061-gxv8y146	11	21	components	component	NNS
cord-024061-gxv8y146	11	22	of	of	IN
cord-024061-gxv8y146	11	23	the	the	DT
cord-024061-gxv8y146	11	24	methodology	methodology	NN
cord-024061-gxv8y146	11	25	in	in	IN
cord-024061-gxv8y146	11	26	one	one	CD
cord-024061-gxv8y146	11	27	analytical	analytical	JJ
cord-024061-gxv8y146	11	28	pipeline	pipeline	NN
cord-024061-gxv8y146	11	29	to	to	TO
cord-024061-gxv8y146	11	30	facilitate	facilitate	VB
cord-024061-gxv8y146	11	31	the	the	DT
cord-024061-gxv8y146	11	32	proper	proper	JJ
cord-024061-gxv8y146	11	33	use	use	NN
cord-024061-gxv8y146	11	34	of	of	IN
cord-024061-gxv8y146	11	35	the	the	DT
cord-024061-gxv8y146	11	36	methods	method	NNS
cord-024061-gxv8y146	11	37	by	by	IN
cord-024061-gxv8y146	11	38	animal	animal	NN
cord-024061-gxv8y146	11	39	health	health	NN
cord-024061-gxv8y146	11	40	researchers	researcher	NNS
cord-024061-gxv8y146	11	41	.	.	.
cord-024061-gxv8y146	12	1	Also	also	RB
cord-024061-gxv8y146	12	2	,	,	,
cord-024061-gxv8y146	12	3	we	-PRON-	PRP
cord-024061-gxv8y146	12	4	challenged	challenge	VBD
cord-024061-gxv8y146	12	5	the	the	DT
cord-024061-gxv8y146	12	6	robustness	robustness	NN
cord-024061-gxv8y146	12	7	of	of	IN
cord-024061-gxv8y146	12	8	the	the	DT
cord-024061-gxv8y146	12	9	posterior	posterior	JJ
cord-024061-gxv8y146	12	10	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	12	11	parameters	parameter	NNS
cord-024061-gxv8y146	12	12	,	,	,
cord-024061-gxv8y146	12	13	inferred	infer	VBN
cord-024061-gxv8y146	12	14	by	by	IN
cord-024061-gxv8y146	12	15	the	the	DT
cord-024061-gxv8y146	12	16	commonly	commonly	RB
cord-024061-gxv8y146	12	17	used	use	VBN
cord-024061-gxv8y146	12	18	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	12	19	models	model	NNS
cord-024061-gxv8y146	12	20	,	,	,
cord-024061-gxv8y146	12	21	using	use	VBG
cord-024061-gxv8y146	12	22	hemagglutinin	hemagglutinin	NN
cord-024061-gxv8y146	12	23	(	(	-LRB-
cord-024061-gxv8y146	12	24	HA	HA	NNP
cord-024061-gxv8y146	12	25	)	)	-RRB-
cord-024061-gxv8y146	12	26	and	and	CC
cord-024061-gxv8y146	12	27	polymerase	polymerase	VB
cord-024061-gxv8y146	12	28	basic	basic	JJ
cord-024061-gxv8y146	12	29	2	2	CD
cord-024061-gxv8y146	12	30	(	(	-LRB-
cord-024061-gxv8y146	12	31	PB2	PB2	NNP
cord-024061-gxv8y146	12	32	)	)	-RRB-
cord-024061-gxv8y146	12	33	segments	segment	NNS
cord-024061-gxv8y146	12	34	of	of	IN
cord-024061-gxv8y146	12	35	the	the	DT
cord-024061-gxv8y146	12	36	currently	currently	RB
cord-024061-gxv8y146	12	37	circulating	circulate	VBG
cord-024061-gxv8y146	12	38	human	human	NN
cord-024061-gxv8y146	12	39	-	-	HYPH
cord-024061-gxv8y146	12	40	like	like	JJ
cord-024061-gxv8y146	12	41	H3	H3	NNP
cord-024061-gxv8y146	12	42	swine	swine	NN
cord-024061-gxv8y146	12	43	influenza	influenza	NN
cord-024061-gxv8y146	12	44	(	(	-LRB-
cord-024061-gxv8y146	12	45	SI	SI	NNP
cord-024061-gxv8y146	12	46	)	)	-RRB-
cord-024061-gxv8y146	12	47	viruses	virus	NNS
cord-024061-gxv8y146	12	48	isolated	isolate	VBN
cord-024061-gxv8y146	12	49	in	in	IN
cord-024061-gxv8y146	12	50	the	the	DT
cord-024061-gxv8y146	12	51	United	United	NNP
cord-024061-gxv8y146	12	52	States	States	NNP
cord-024061-gxv8y146	12	53	and	and	CC
cord-024061-gxv8y146	12	54	multiple	multiple	JJ
cord-024061-gxv8y146	12	55	priors	prior	NNS
cord-024061-gxv8y146	12	56	.	.	.
cord-024061-gxv8y146	13	1	Subsequently	subsequently	RB
cord-024061-gxv8y146	13	2	,	,	,
cord-024061-gxv8y146	13	3	we	-PRON-	PRP
cord-024061-gxv8y146	13	4	compared	compare	VBD
cord-024061-gxv8y146	13	5	similarities	similarity	NNS
cord-024061-gxv8y146	13	6	and	and	CC
cord-024061-gxv8y146	13	7	differences	difference	NNS
cord-024061-gxv8y146	13	8	between	between	IN
cord-024061-gxv8y146	13	9	the	the	DT
cord-024061-gxv8y146	13	10	posterior	posterior	JJ
cord-024061-gxv8y146	13	11	parameters	parameter	NNS
cord-024061-gxv8y146	13	12	inferred	infer	VBN
cord-024061-gxv8y146	13	13	from	from	IN
cord-024061-gxv8y146	13	14	sequence	sequence	NN
cord-024061-gxv8y146	13	15	data	datum	NNS
cord-024061-gxv8y146	13	16	using	use	VBG
cord-024061-gxv8y146	13	17	multiple	multiple	JJ
cord-024061-gxv8y146	13	18	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	13	19	models	model	NNS
cord-024061-gxv8y146	13	20	.	.	.
cord-024061-gxv8y146	14	1	Our	-PRON-	PRP$
cord-024061-gxv8y146	14	2	suggested	suggest	VBN
cord-024061-gxv8y146	14	3	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	14	4	approach	approach	NN
cord-024061-gxv8y146	14	5	attempts	attempt	VBZ
cord-024061-gxv8y146	14	6	to	to	TO
cord-024061-gxv8y146	14	7	reduce	reduce	VB
cord-024061-gxv8y146	14	8	the	the	DT
cord-024061-gxv8y146	14	9	impact	impact	NN
cord-024061-gxv8y146	14	10	of	of	IN
cord-024061-gxv8y146	14	11	its	-PRON-	PRP$
cord-024061-gxv8y146	14	12	inherent	inherent	JJ
cord-024061-gxv8y146	14	13	limitations	limitation	NNS
cord-024061-gxv8y146	14	14	to	to	TO
cord-024061-gxv8y146	14	15	offer	offer	VB
cord-024061-gxv8y146	14	16	less	less	RBR
cord-024061-gxv8y146	14	17	biased	biased	JJ
cord-024061-gxv8y146	14	18	and	and	CC
cord-024061-gxv8y146	14	19	biologically	biologically	RB
cord-024061-gxv8y146	14	20	plausible	plausible	JJ
cord-024061-gxv8y146	14	21	inferences	inference	NNS
cord-024061-gxv8y146	14	22	about	about	IN
cord-024061-gxv8y146	14	23	the	the	DT
cord-024061-gxv8y146	14	24	pathogen	pathogen	NN
cord-024061-gxv8y146	14	25	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	14	26	characteristics	characteristic	NNS
cord-024061-gxv8y146	14	27	to	to	TO
cord-024061-gxv8y146	14	28	properly	properly	RB
cord-024061-gxv8y146	14	29	guide	guide	VB
cord-024061-gxv8y146	14	30	intervention	intervention	NN
cord-024061-gxv8y146	14	31	activities	activity	NNS
cord-024061-gxv8y146	14	32	.	.	.
cord-024061-gxv8y146	15	1	We	-PRON-	PRP
cord-024061-gxv8y146	15	2	also	also	RB
cord-024061-gxv8y146	15	3	pinpointed	pinpoint	VBD
cord-024061-gxv8y146	15	4	requirements	requirement	NNS
cord-024061-gxv8y146	15	5	and	and	CC
cord-024061-gxv8y146	15	6	challenges	challenge	NNS
cord-024061-gxv8y146	15	7	for	for	IN
cord-024061-gxv8y146	15	8	integrating	integrate	VBG
cord-024061-gxv8y146	15	9	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	15	10	methods	method	NNS
cord-024061-gxv8y146	15	11	in	in	IN
cord-024061-gxv8y146	15	12	routine	routine	JJ
cord-024061-gxv8y146	15	13	animal	animal	NN
cord-024061-gxv8y146	15	14	disease	disease	NN
cord-024061-gxv8y146	15	15	surveillance	surveillance	NN
cord-024061-gxv8y146	15	16	activities	activity	NNS
cord-024061-gxv8y146	15	17	.	.	.
cord-024061-gxv8y146	16	1	In	in	IN
cord-024061-gxv8y146	16	2	the	the	DT
cord-024061-gxv8y146	16	3	past	past	JJ
cord-024061-gxv8y146	16	4	few	few	JJ
cord-024061-gxv8y146	16	5	decades	decade	NNS
cord-024061-gxv8y146	16	6	,	,	,
cord-024061-gxv8y146	16	7	genetic	genetic	JJ
cord-024061-gxv8y146	16	8	analysis	analysis	NN
cord-024061-gxv8y146	16	9	of	of	IN
cord-024061-gxv8y146	16	10	rapidly	rapidly	RB
cord-024061-gxv8y146	16	11	evolving	evolve	VBG
cord-024061-gxv8y146	16	12	pathogens	pathogen	NNS
cord-024061-gxv8y146	16	13	has	have	VBZ
cord-024061-gxv8y146	16	14	become	become	VBN
cord-024061-gxv8y146	16	15	an	an	DT
cord-024061-gxv8y146	16	16	integral	integral	JJ
cord-024061-gxv8y146	16	17	part	part	NN
cord-024061-gxv8y146	16	18	of	of	IN
cord-024061-gxv8y146	16	19	animal	animal	NN
cord-024061-gxv8y146	16	20	disease	disease	NN
cord-024061-gxv8y146	16	21	surveillance	surveillance	NN
cord-024061-gxv8y146	16	22	systems	system	NNS
cord-024061-gxv8y146	16	23	worldwide	worldwide	RB
cord-024061-gxv8y146	16	24	(	(	-LRB-
cord-024061-gxv8y146	16	25	1	1	CD
cord-024061-gxv8y146	16	26	)	)	-RRB-
cord-024061-gxv8y146	16	27	(	(	-LRB-
cord-024061-gxv8y146	16	28	2	2	LS
cord-024061-gxv8y146	16	29	)	)	-RRB-
cord-024061-gxv8y146	16	30	(	(	-LRB-
cord-024061-gxv8y146	16	31	3	3	LS
cord-024061-gxv8y146	16	32	)	)	-RRB-
cord-024061-gxv8y146	16	33	(	(	-LRB-
cord-024061-gxv8y146	16	34	4	4	LS
cord-024061-gxv8y146	16	35	)	)	-RRB-
cord-024061-gxv8y146	16	36	.	.	.
cord-024061-gxv8y146	17	1	Most	most	RBS
cord-024061-gxv8y146	17	2	current	current	JJ
cord-024061-gxv8y146	17	3	and	and	CC
cord-024061-gxv8y146	17	4	past	past	JJ
cord-024061-gxv8y146	17	5	molecular	molecular	JJ
cord-024061-gxv8y146	17	6	surveillance	surveillance	NN
cord-024061-gxv8y146	17	7	studies	study	NNS
cord-024061-gxv8y146	17	8	of	of	IN
cord-024061-gxv8y146	17	9	animal	animal	NN
cord-024061-gxv8y146	17	10	disease	disease	NN
cord-024061-gxv8y146	17	11	pathogens	pathogen	NNS
cord-024061-gxv8y146	17	12	of	of	IN
cord-024061-gxv8y146	17	13	both	both	DT
cord-024061-gxv8y146	17	14	public	public	JJ
cord-024061-gxv8y146	17	15	health	health	NN
cord-024061-gxv8y146	17	16	and	and	CC
cord-024061-gxv8y146	17	17	economical	economical	JJ
cord-024061-gxv8y146	17	18	importance	importance	NN
cord-024061-gxv8y146	17	19	such	such	JJ
cord-024061-gxv8y146	17	20	as	as	IN
cord-024061-gxv8y146	17	21	influenza	influenza	NN
cord-024061-gxv8y146	17	22	(	(	-LRB-
cord-024061-gxv8y146	17	23	5	5	LS
cord-024061-gxv8y146	17	24	)	)	-RRB-
cord-024061-gxv8y146	17	25	(	(	-LRB-
cord-024061-gxv8y146	17	26	6	6	LS
cord-024061-gxv8y146	17	27	)	)	-RRB-
cord-024061-gxv8y146	17	28	(	(	-LRB-
cord-024061-gxv8y146	17	29	7	7	CD
cord-024061-gxv8y146	17	30	)	)	-RRB-
cord-024061-gxv8y146	17	31	,	,	,
cord-024061-gxv8y146	17	32	foot	foot	NN
cord-024061-gxv8y146	17	33	-	-	HYPH
cord-024061-gxv8y146	17	34	and	and	CC
cord-024061-gxv8y146	17	35	-	-	HYPH
cord-024061-gxv8y146	17	36	mouth	mouth	NN
cord-024061-gxv8y146	17	37	disease	disease	NN
cord-024061-gxv8y146	17	38	(	(	-LRB-
cord-024061-gxv8y146	17	39	FMD	FMD	NNP
cord-024061-gxv8y146	17	40	)	)	-RRB-
cord-024061-gxv8y146	17	41	(	(	-LRB-
cord-024061-gxv8y146	17	42	8)	8)	NNP
cord-024061-gxv8y146	17	43	(	(	-LRB-
cord-024061-gxv8y146	17	44	9	9	CD
cord-024061-gxv8y146	17	45	)	)	-RRB-
cord-024061-gxv8y146	17	46	(	(	-LRB-
cord-024061-gxv8y146	17	47	10	10	CD
cord-024061-gxv8y146	17	48	)	)	-RRB-
cord-024061-gxv8y146	17	49	,	,	,
cord-024061-gxv8y146	17	50	and	and	CC
cord-024061-gxv8y146	17	51	porcine	porcine	JJ
cord-024061-gxv8y146	17	52	reproductive	reproductive	JJ
cord-024061-gxv8y146	17	53	and	and	CC
cord-024061-gxv8y146	17	54	respiratory	respiratory	JJ
cord-024061-gxv8y146	17	55	syndrome	syndrome	NN
cord-024061-gxv8y146	17	56	(	(	-LRB-
cord-024061-gxv8y146	17	57	PRRS	PRRS	NNP
cord-024061-gxv8y146	17	58	)	)	-RRB-
cord-024061-gxv8y146	18	1	(	(	-LRB-
cord-024061-gxv8y146	18	2	11	11	CD
cord-024061-gxv8y146	18	3	)	)	-RRB-
cord-024061-gxv8y146	18	4	(	(	-LRB-
cord-024061-gxv8y146	18	5	12	12	CD
cord-024061-gxv8y146	18	6	)	)	-RRB-
cord-024061-gxv8y146	18	7	(	(	-LRB-
cord-024061-gxv8y146	18	8	13	13	CD
cord-024061-gxv8y146	18	9	)	)	-RRB-
cord-024061-gxv8y146	18	10	viruses	virus	NNS
cord-024061-gxv8y146	18	11	are	be	VBP
cord-024061-gxv8y146	18	12	dependent	dependent	JJ
cord-024061-gxv8y146	18	13	on	on	IN
cord-024061-gxv8y146	18	14	classical	classical	JJ
cord-024061-gxv8y146	18	15	epidemiological	epidemiological	JJ
cord-024061-gxv8y146	18	16	and	and	CC
cord-024061-gxv8y146	18	17	phylogenetic	phylogenetic	JJ
cord-024061-gxv8y146	18	18	methods	method	NNS
cord-024061-gxv8y146	18	19	.	.	.
cord-024061-gxv8y146	19	1	These	these	DT
cord-024061-gxv8y146	19	2	studies	study	NNS
cord-024061-gxv8y146	19	3	or	or	CC
cord-024061-gxv8y146	19	4	surveillance	surveillance	NN
cord-024061-gxv8y146	19	5	systems	system	NNS
cord-024061-gxv8y146	19	6	used	use	VBD
cord-024061-gxv8y146	19	7	classical	classical	JJ
cord-024061-gxv8y146	19	8	phylogenetic	phylogenetic	JJ
cord-024061-gxv8y146	19	9	methods	method	NNS
cord-024061-gxv8y146	19	10	,	,	,
cord-024061-gxv8y146	19	11	including	include	VBG
cord-024061-gxv8y146	19	12	parsimony	parsimony	NN
cord-024061-gxv8y146	19	13	,	,	,
cord-024061-gxv8y146	19	14	neighbor	neighbor	NN
cord-024061-gxv8y146	19	15	-	-	HYPH
cord-024061-gxv8y146	19	16	joining	joining	NN
cord-024061-gxv8y146	19	17	,	,	,
cord-024061-gxv8y146	19	18	or	or	CC
cord-024061-gxv8y146	19	19	maximum	maximum	JJ
cord-024061-gxv8y146	19	20	likelihood	likelihood	NN
cord-024061-gxv8y146	19	21	(	(	-LRB-
cord-024061-gxv8y146	19	22	ML	ml	NN
cord-024061-gxv8y146	19	23	)	)	-RRB-
cord-024061-gxv8y146	19	24	approaches	approach	VBZ
cord-024061-gxv8y146	19	25	to	to	IN
cord-024061-gxv8y146	19	26	either	either	DT
cord-024061-gxv8y146	19	27	genotype	genotype	NN
cord-024061-gxv8y146	19	28	novel	novel	NN
cord-024061-gxv8y146	19	29	emerging	emerge	VBG
cord-024061-gxv8y146	19	30	strains	strain	NNS
cord-024061-gxv8y146	19	31	,	,	,
cord-024061-gxv8y146	19	32	classify	classify	VB
cord-024061-gxv8y146	19	33	viral	viral	JJ
cord-024061-gxv8y146	19	34	lineages	lineage	NNS
cord-024061-gxv8y146	19	35	,	,	,
cord-024061-gxv8y146	19	36	or	or	CC
cord-024061-gxv8y146	19	37	assess	assess	VB
cord-024061-gxv8y146	19	38	tree	tree	NN
cord-024061-gxv8y146	19	39	topologies	topology	NNS
cord-024061-gxv8y146	19	40	to	to	TO
cord-024061-gxv8y146	19	41	distinguish	distinguish	VB
cord-024061-gxv8y146	19	42	between	between	IN
cord-024061-gxv8y146	19	43	novel	novel	NN
cord-024061-gxv8y146	19	44	and	and	CC
cord-024061-gxv8y146	19	45	emerging	emerge	VBG
cord-024061-gxv8y146	19	46	strains	strain	NNS
cord-024061-gxv8y146	19	47	(	(	-LRB-
cord-024061-gxv8y146	19	48	6	6	CD
cord-024061-gxv8y146	19	49	,	,	,
cord-024061-gxv8y146	19	50	7	7	CD
cord-024061-gxv8y146	19	51	,	,	,
cord-024061-gxv8y146	19	52	13	13	CD
cord-024061-gxv8y146	19	53	)	)	-RRB-
cord-024061-gxv8y146	19	54	.	.	.
cord-024061-gxv8y146	20	1	In	in	IN
cord-024061-gxv8y146	20	2	addition	addition	NN
cord-024061-gxv8y146	20	3	,	,	,
cord-024061-gxv8y146	20	4	classical	classical	JJ
cord-024061-gxv8y146	20	5	phylogenetic	phylogenetic	NN
cord-024061-gxv8y146	20	6	approaches	approach	NNS
cord-024061-gxv8y146	20	7	were	be	VBD
cord-024061-gxv8y146	20	8	used	use	VBN
cord-024061-gxv8y146	20	9	to	to	TO
cord-024061-gxv8y146	20	10	assess	assess	VB
cord-024061-gxv8y146	20	11	correlations	correlation	NNS
cord-024061-gxv8y146	20	12	between	between	IN
cord-024061-gxv8y146	20	13	the	the	DT
cord-024061-gxv8y146	20	14	similarities	similarity	NNS
cord-024061-gxv8y146	20	15	of	of	IN
cord-024061-gxv8y146	20	16	nucleotide	nucleotide	JJ
cord-024061-gxv8y146	20	17	sequences	sequence	NNS
cord-024061-gxv8y146	20	18	and	and	CC
cord-024061-gxv8y146	20	19	related	relate	VBN
cord-024061-gxv8y146	20	20	epidemiological	epidemiological	JJ
cord-024061-gxv8y146	20	21	characteristics	characteristic	NNS
cord-024061-gxv8y146	20	22	,	,	,
cord-024061-gxv8y146	20	23	while	while	IN
cord-024061-gxv8y146	20	24	ignoring	ignore	VBG
cord-024061-gxv8y146	20	25	uncertainties	uncertainty	NNS
cord-024061-gxv8y146	20	26	associated	associate	VBN
cord-024061-gxv8y146	20	27	with	with	IN
cord-024061-gxv8y146	20	28	estimates	estimate	NNS
cord-024061-gxv8y146	20	29	of	of	IN
cord-024061-gxv8y146	20	30	phylogenetic	phylogenetic	JJ
cord-024061-gxv8y146	20	31	relationships	relationship	NNS
cord-024061-gxv8y146	20	32	,	,	,
cord-024061-gxv8y146	20	33	host	host	NN
cord-024061-gxv8y146	20	34	,	,	,
cord-024061-gxv8y146	20	35	temporal	temporal	JJ
cord-024061-gxv8y146	20	36	,	,	,
cord-024061-gxv8y146	20	37	and	and	CC
cord-024061-gxv8y146	20	38	spatial	spatial	JJ
cord-024061-gxv8y146	20	39	factors	factor	NNS
cord-024061-gxv8y146	20	40	(	(	-LRB-
cord-024061-gxv8y146	20	41	7	7	CD
cord-024061-gxv8y146	20	42	,	,	,
cord-024061-gxv8y146	20	43	10	10	CD
cord-024061-gxv8y146	20	44	,	,	,
cord-024061-gxv8y146	20	45	11	11	CD
cord-024061-gxv8y146	20	46	,	,	,
cord-024061-gxv8y146	20	47	14	14	CD
cord-024061-gxv8y146	20	48	)	)	-RRB-
cord-024061-gxv8y146	20	49	.	.	.
cord-024061-gxv8y146	21	1	Furthermore	furthermore	RB
cord-024061-gxv8y146	21	2	,	,	,
cord-024061-gxv8y146	21	3	they	-PRON-	PRP
cord-024061-gxv8y146	21	4	investigated	investigate	VBD
cord-024061-gxv8y146	21	5	spatio	spatio	JJ
cord-024061-gxv8y146	21	6	-	-	HYPH
cord-024061-gxv8y146	21	7	temporal	temporal	JJ
cord-024061-gxv8y146	21	8	and	and	CC
cord-024061-gxv8y146	21	9	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	21	10	dynamics	dynamic	NNS
cord-024061-gxv8y146	21	11	of	of	IN
cord-024061-gxv8y146	21	12	the	the	DT
cord-024061-gxv8y146	21	13	virus	virus	NN
cord-024061-gxv8y146	21	14	isolates	isolate	VBZ
cord-024061-gxv8y146	21	15	in	in	IN
cord-024061-gxv8y146	21	16	a	a	DT
cord-024061-gxv8y146	21	17	disjointed	disjointed	JJ
cord-024061-gxv8y146	21	18	analytical	analytical	JJ
cord-024061-gxv8y146	21	19	framework	framework	NN
cord-024061-gxv8y146	21	20	and	and	CC
cord-024061-gxv8y146	21	21	made	make	VBD
cord-024061-gxv8y146	21	22	joint	joint	JJ
cord-024061-gxv8y146	21	23	conclusions	conclusion	NNS
cord-024061-gxv8y146	21	24	from	from	IN
cord-024061-gxv8y146	21	25	both	both	DT
cord-024061-gxv8y146	21	26	analytical	analytical	JJ
cord-024061-gxv8y146	21	27	approaches	approach	NNS
cord-024061-gxv8y146	21	28	(	(	-LRB-
cord-024061-gxv8y146	21	29	7	7	CD
cord-024061-gxv8y146	21	30	,	,	,
cord-024061-gxv8y146	21	31	10	10	CD
cord-024061-gxv8y146	21	32	,	,	,
cord-024061-gxv8y146	21	33	11	11	CD
cord-024061-gxv8y146	21	34	,	,	,
cord-024061-gxv8y146	21	35	14	14	CD
cord-024061-gxv8y146	21	36	)	)	-RRB-
cord-024061-gxv8y146	21	37	.	.	.
cord-024061-gxv8y146	22	1	Therefore	therefore	RB
cord-024061-gxv8y146	22	2	,	,	,
cord-024061-gxv8y146	22	3	many	many	JJ
cord-024061-gxv8y146	22	4	of	of	IN
cord-024061-gxv8y146	22	5	the	the	DT
cord-024061-gxv8y146	22	6	past	past	JJ
cord-024061-gxv8y146	22	7	and	and	CC
cord-024061-gxv8y146	22	8	current	current	JJ
cord-024061-gxv8y146	22	9	molecular	molecular	JJ
cord-024061-gxv8y146	22	10	surveillance	surveillance	NN
cord-024061-gxv8y146	22	11	studies	study	NNS
cord-024061-gxv8y146	22	12	of	of	IN
cord-024061-gxv8y146	22	13	animal	animal	NN
cord-024061-gxv8y146	22	14	diseases	disease	NNS
cord-024061-gxv8y146	22	15	have	have	VBP
cord-024061-gxv8y146	22	16	ignored	ignore	VBN
cord-024061-gxv8y146	22	17	that	that	IN
cord-024061-gxv8y146	22	18	epidemiological	epidemiological	JJ
cord-024061-gxv8y146	22	19	and	and	CC
cord-024061-gxv8y146	22	20	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	22	21	dynamics	dynamic	NNS
cord-024061-gxv8y146	22	22	of	of	IN
cord-024061-gxv8y146	22	23	rapidly	rapidly	RB
cord-024061-gxv8y146	22	24	evolving	evolve	VBG
cord-024061-gxv8y146	22	25	viruses	virus	NNS
cord-024061-gxv8y146	22	26	occur	occur	VBP
cord-024061-gxv8y146	22	27	on	on	IN
cord-024061-gxv8y146	22	28	approximately	approximately	RB
cord-024061-gxv8y146	22	29	the	the	DT
cord-024061-gxv8y146	22	30	same	same	JJ
cord-024061-gxv8y146	22	31	time	time	NN
cord-024061-gxv8y146	22	32	-	-	HYPH
cord-024061-gxv8y146	22	33	scale	scale	NN
cord-024061-gxv8y146	22	34	(	(	-LRB-
cord-024061-gxv8y146	22	35	15	15	CD
cord-024061-gxv8y146	22	36	)	)	-RRB-
cord-024061-gxv8y146	22	37	.	.	.
cord-024061-gxv8y146	23	1	Thus	thus	RB
cord-024061-gxv8y146	23	2	,	,	,
cord-024061-gxv8y146	23	3	studying	study	VBG
cord-024061-gxv8y146	23	4	them	-PRON-	PRP
cord-024061-gxv8y146	23	5	in	in	IN
cord-024061-gxv8y146	23	6	a	a	DT
cord-024061-gxv8y146	23	7	unified	unified	JJ
cord-024061-gxv8y146	23	8	analytical	analytical	JJ
cord-024061-gxv8y146	23	9	framework	framework	NN
cord-024061-gxv8y146	23	10	will	will	MD
cord-024061-gxv8y146	23	11	refine	refine	VB
cord-024061-gxv8y146	23	12	their	-PRON-	PRP$
cord-024061-gxv8y146	23	13	interpretations	interpretation	NNS
cord-024061-gxv8y146	23	14	and	and	CC
cord-024061-gxv8y146	23	15	limit	limit	VB
cord-024061-gxv8y146	23	16	biased	biased	JJ
cord-024061-gxv8y146	23	17	conclusions	conclusion	NNS
cord-024061-gxv8y146	23	18	to	to	TO
cord-024061-gxv8y146	23	19	subsequently	subsequently	RB
cord-024061-gxv8y146	23	20	improving	improve	VBG
cord-024061-gxv8y146	23	21	the	the	DT
cord-024061-gxv8y146	23	22	related	relate	VBN
cord-024061-gxv8y146	23	23	molecular	molecular	JJ
cord-024061-gxv8y146	23	24	surveillance	surveillance	NN
cord-024061-gxv8y146	23	25	activities	activity	NNS
cord-024061-gxv8y146	23	26	.	.	.
cord-024061-gxv8y146	24	1	Classical	classical	JJ
cord-024061-gxv8y146	24	2	phylogenetic	phylogenetic	NN
cord-024061-gxv8y146	24	3	approaches	approach	NNS
cord-024061-gxv8y146	24	4	are	be	VBP
cord-024061-gxv8y146	24	5	not	not	RB
cord-024061-gxv8y146	24	6	capable	capable	JJ
cord-024061-gxv8y146	24	7	of	of	IN
cord-024061-gxv8y146	24	8	accounting	account	VBG
cord-024061-gxv8y146	24	9	for	for	IN
cord-024061-gxv8y146	24	10	the	the	DT
cord-024061-gxv8y146	24	11	uncertainties	uncertainty	NNS
cord-024061-gxv8y146	24	12	in	in	IN
cord-024061-gxv8y146	24	13	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	24	14	processes	process	NNS
cord-024061-gxv8y146	24	15	of	of	IN
cord-024061-gxv8y146	24	16	rapidly	rapidly	RB
cord-024061-gxv8y146	24	17	evolving	evolve	VBG
cord-024061-gxv8y146	24	18	pathogens	pathogen	NNS
cord-024061-gxv8y146	24	19	or	or	CC
cord-024061-gxv8y146	24	20	integrating	integrate	VBG
cord-024061-gxv8y146	24	21	related	related	JJ
cord-024061-gxv8y146	24	22	epidemiological	epidemiological	JJ
cord-024061-gxv8y146	24	23	features	feature	NNS
cord-024061-gxv8y146	24	24	into	into	IN
cord-024061-gxv8y146	24	25	their	-PRON-	PRP$
cord-024061-gxv8y146	24	26	phylogeny	phylogeny	NN
cord-024061-gxv8y146	24	27	,	,	,
cord-024061-gxv8y146	24	28	which	which	WDT
cord-024061-gxv8y146	24	29	is	be	VBZ
cord-024061-gxv8y146	24	30	an	an	DT
cord-024061-gxv8y146	24	31	important	important	JJ
cord-024061-gxv8y146	24	32	advantage	advantage	NN
cord-024061-gxv8y146	24	33	of	of	IN
cord-024061-gxv8y146	24	34	Bayesian	bayesian	JJ
cord-024061-gxv8y146	24	35	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	24	36	methods	method	NNS
cord-024061-gxv8y146	24	37	.	.	.
cord-024061-gxv8y146	25	1	The	the	DT
cord-024061-gxv8y146	25	2	Bayesian	bayesian	JJ
cord-024061-gxv8y146	25	3	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	25	4	methods	method	NNS
cord-024061-gxv8y146	25	5	were	be	VBD
cord-024061-gxv8y146	25	6	borrowed	borrow	VBN
cord-024061-gxv8y146	25	7	from	from	IN
cord-024061-gxv8y146	25	8	the	the	DT
cord-024061-gxv8y146	25	9	field	field	NN
cord-024061-gxv8y146	25	10	of	of	IN
cord-024061-gxv8y146	25	11	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	25	12	biology	biology	NN
cord-024061-gxv8y146	25	13	and	and	CC
cord-024061-gxv8y146	25	14	have	have	VBP
cord-024061-gxv8y146	25	15	become	become	VBN
cord-024061-gxv8y146	25	16	a	a	DT
cord-024061-gxv8y146	25	17	powerful	powerful	JJ
cord-024061-gxv8y146	25	18	tool	tool	NN
cord-024061-gxv8y146	25	19	for	for	IN
cord-024061-gxv8y146	25	20	exploring	explore	VBG
cord-024061-gxv8y146	25	21	the	the	DT
cord-024061-gxv8y146	25	22	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	25	23	epidemiology	epidemiology	NN
cord-024061-gxv8y146	25	24	of	of	IN
cord-024061-gxv8y146	25	25	infectious	infectious	JJ
cord-024061-gxv8y146	25	26	pathogens	pathogen	NNS
cord-024061-gxv8y146	25	27	(	(	-LRB-
cord-024061-gxv8y146	25	28	14	14	CD
cord-024061-gxv8y146	25	29	)	)	-RRB-
cord-024061-gxv8y146	25	30	(	(	-LRB-
cord-024061-gxv8y146	25	31	15	15	CD
cord-024061-gxv8y146	25	32	)	)	-RRB-
cord-024061-gxv8y146	25	33	(	(	-LRB-
cord-024061-gxv8y146	25	34	16	16	CD
cord-024061-gxv8y146	25	35	)	)	-RRB-
cord-024061-gxv8y146	25	36	(	(	-LRB-
cord-024061-gxv8y146	25	37	17	17	CD
cord-024061-gxv8y146	25	38	)	)	-RRB-
cord-024061-gxv8y146	25	39	.	.	.
cord-024061-gxv8y146	26	1	During	during	IN
cord-024061-gxv8y146	26	2	the	the	DT
cord-024061-gxv8y146	26	3	last	last	JJ
cord-024061-gxv8y146	26	4	two	two	CD
cord-024061-gxv8y146	26	5	decades	decade	NNS
cord-024061-gxv8y146	26	6	,	,	,
cord-024061-gxv8y146	26	7	the	the	DT
cord-024061-gxv8y146	26	8	rapid	rapid	JJ
cord-024061-gxv8y146	26	9	growth	growth	NN
cord-024061-gxv8y146	26	10	of	of	IN
cord-024061-gxv8y146	26	11	pathogens	pathogen	NNS
cord-024061-gxv8y146	26	12	'	'	POS
cord-024061-gxv8y146	26	13	genetic	genetic	JJ
cord-024061-gxv8y146	26	14	data	datum	NNS
cord-024061-gxv8y146	26	15	and	and	CC
cord-024061-gxv8y146	26	16	computational	computational	JJ
cord-024061-gxv8y146	26	17	resources	resource	NNS
cord-024061-gxv8y146	26	18	increased	increase	VBD
cord-024061-gxv8y146	26	19	the	the	DT
cord-024061-gxv8y146	26	20	applications	application	NNS
cord-024061-gxv8y146	26	21	of	of	IN
cord-024061-gxv8y146	26	22	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	26	23	methods	method	NNS
cord-024061-gxv8y146	26	24	in	in	IN
cord-024061-gxv8y146	26	25	animal	animal	NN
cord-024061-gxv8y146	26	26	and	and	CC
cord-024061-gxv8y146	26	27	human	human	JJ
cord-024061-gxv8y146	26	28	disease	disease	NN
cord-024061-gxv8y146	26	29	surveillance	surveillance	NN
cord-024061-gxv8y146	26	30	(	(	-LRB-
cord-024061-gxv8y146	26	31	17	17	CD
cord-024061-gxv8y146	26	32	)	)	-RRB-
cord-024061-gxv8y146	26	33	.	.	.
cord-024061-gxv8y146	27	1	These	these	DT
cord-024061-gxv8y146	27	2	methods	method	NNS
cord-024061-gxv8y146	27	3	are	be	VBP
cord-024061-gxv8y146	27	4	capable	capable	JJ
cord-024061-gxv8y146	27	5	of	of	IN
cord-024061-gxv8y146	27	6	accounting	account	VBG
cord-024061-gxv8y146	27	7	for	for	IN
cord-024061-gxv8y146	27	8	uncertainties	uncertainty	NNS
cord-024061-gxv8y146	27	9	,	,	,
cord-024061-gxv8y146	27	10	and	and	CC
cord-024061-gxv8y146	27	11	uniquely	uniquely	RB
cord-024061-gxv8y146	27	12	integrate	integrate	VB
cord-024061-gxv8y146	27	13	complex	complex	JJ
cord-024061-gxv8y146	27	14	epidemiological	epidemiological	JJ
cord-024061-gxv8y146	27	15	and	and	CC
cord-024061-gxv8y146	27	16	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	27	17	processes	process	NNS
cord-024061-gxv8y146	27	18	in	in	IN
cord-024061-gxv8y146	27	19	populations	population	NNS
cord-024061-gxv8y146	27	20	using	use	VBG
cord-024061-gxv8y146	27	21	a	a	DT
cord-024061-gxv8y146	27	22	single	single	JJ
cord-024061-gxv8y146	27	23	Bayesian	bayesian	JJ
cord-024061-gxv8y146	27	24	statistical	statistical	JJ
cord-024061-gxv8y146	27	25	framework	framework	NN
cord-024061-gxv8y146	27	26	(	(	-LRB-
cord-024061-gxv8y146	27	27	18	18	CD
cord-024061-gxv8y146	27	28	,	,	,
cord-024061-gxv8y146	27	29	19	19	CD
cord-024061-gxv8y146	27	30	)	)	-RRB-
cord-024061-gxv8y146	27	31	.	.	.
cord-024061-gxv8y146	28	1	This	this	DT
cord-024061-gxv8y146	28	2	framework	framework	NN
cord-024061-gxv8y146	28	3	handles	handle	VBZ
cord-024061-gxv8y146	28	4	the	the	DT
cord-024061-gxv8y146	28	5	parameters	parameter	NNS
cord-024061-gxv8y146	28	6	of	of	IN
cord-024061-gxv8y146	28	7	the	the	DT
cord-024061-gxv8y146	28	8	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	28	9	model	model	NN
cord-024061-gxv8y146	28	10	as	as	IN
cord-024061-gxv8y146	28	11	random	random	JJ
cord-024061-gxv8y146	28	12	variables	variable	NNS
cord-024061-gxv8y146	28	13	,	,	,
cord-024061-gxv8y146	28	14	in	in	IN
cord-024061-gxv8y146	28	15	which	which	WDT
cord-024061-gxv8y146	28	16	each	each	DT
cord-024061-gxv8y146	28	17	parameter	parameter	NN
cord-024061-gxv8y146	28	18	is	be	VBZ
cord-024061-gxv8y146	28	19	set	set	VBN
cord-024061-gxv8y146	28	20	by	by	IN
cord-024061-gxv8y146	28	21	a	a	DT
cord-024061-gxv8y146	28	22	specified	specify	VBN
cord-024061-gxv8y146	28	23	prior	prior	JJ
cord-024061-gxv8y146	28	24	probability	probability	NN
cord-024061-gxv8y146	28	25	distribution	distribution	NN
cord-024061-gxv8y146	28	26	(	(	-LRB-
cord-024061-gxv8y146	28	27	and	and	CC
cord-024061-gxv8y146	28	28	a	a	DT
cord-024061-gxv8y146	28	29	parallel	parallel	NN
cord-024061-gxv8y146	28	30	inferred	infer	VBN
cord-024061-gxv8y146	28	31	posterior	posterior	JJ
cord-024061-gxv8y146	28	32	probability	probability	NN
cord-024061-gxv8y146	28	33	distribution	distribution	NN
cord-024061-gxv8y146	28	34	)	)	-RRB-
cord-024061-gxv8y146	28	35	.	.	.
cord-024061-gxv8y146	29	1	Therefore	therefore	RB
cord-024061-gxv8y146	29	2	,	,	,
cord-024061-gxv8y146	29	3	this	this	DT
cord-024061-gxv8y146	29	4	innovative	innovative	JJ
cord-024061-gxv8y146	29	5	quantitative	quantitative	JJ
cord-024061-gxv8y146	29	6	integration	integration	NN
cord-024061-gxv8y146	29	7	improved	improve	VBD
cord-024061-gxv8y146	29	8	disease	disease	NN
cord-024061-gxv8y146	29	9	investigation	investigation	NN
cord-024061-gxv8y146	29	10	by	by	IN
cord-024061-gxv8y146	29	11	answering	answer	VBG
cord-024061-gxv8y146	29	12	novel	novel	JJ
cord-024061-gxv8y146	29	13	epidemiological	epidemiological	JJ
cord-024061-gxv8y146	29	14	questions	question	NNS
cord-024061-gxv8y146	29	15	about	about	IN
cord-024061-gxv8y146	29	16	the	the	DT
cord-024061-gxv8y146	29	17	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	29	18	history	history	NN
cord-024061-gxv8y146	29	19	,	,	,
cord-024061-gxv8y146	29	20	spatiotemporal	spatiotemporal	JJ
cord-024061-gxv8y146	29	21	origins	origin	NNS
cord-024061-gxv8y146	29	22	,	,	,
cord-024061-gxv8y146	29	23	within	within	IN
cord-024061-gxv8y146	29	24	and	and	CC
cord-024061-gxv8y146	29	25	between	between	IN
cord-024061-gxv8y146	29	26	-	-	HYPH
cord-024061-gxv8y146	29	27	host	host	NN
cord-024061-gxv8y146	29	28	transmission	transmission	NN
cord-024061-gxv8y146	29	29	,	,	,
cord-024061-gxv8y146	29	30	and	and	CC
cord-024061-gxv8y146	29	31	environmental	environmental	JJ
cord-024061-gxv8y146	29	32	risk	risk	NN
cord-024061-gxv8y146	29	33	factors	factor	NNS
cord-024061-gxv8y146	29	34	for	for	IN
cord-024061-gxv8y146	29	35	rapidly	rapidly	RB
cord-024061-gxv8y146	29	36	evolving	evolve	VBG
cord-024061-gxv8y146	29	37	pathogens	pathogen	NNS
cord-024061-gxv8y146	29	38	(	(	-LRB-
cord-024061-gxv8y146	29	39	17	17	CD
cord-024061-gxv8y146	29	40	)	)	-RRB-
cord-024061-gxv8y146	29	41	.	.	.
cord-024061-gxv8y146	30	1	In	in	IN
cord-024061-gxv8y146	30	2	fact	fact	NN
cord-024061-gxv8y146	30	3	,	,	,
cord-024061-gxv8y146	30	4	during	during	IN
cord-024061-gxv8y146	30	5	the	the	DT
cord-024061-gxv8y146	30	6	last	last	JJ
cord-024061-gxv8y146	30	7	decade	decade	NN
cord-024061-gxv8y146	30	8	,	,	,
cord-024061-gxv8y146	30	9	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	30	10	models	model	NNS
cord-024061-gxv8y146	30	11	have	have	VBP
cord-024061-gxv8y146	30	12	become	become	VBN
cord-024061-gxv8y146	30	13	well	well	RB
cord-024061-gxv8y146	30	14	-	-	HYPH
cord-024061-gxv8y146	30	15	established	establish	VBN
cord-024061-gxv8y146	30	16	tools	tool	NNS
cord-024061-gxv8y146	30	17	for	for	IN
cord-024061-gxv8y146	30	18	studying	study	VBG
cord-024061-gxv8y146	30	19	the	the	DT
cord-024061-gxv8y146	30	20	evolution	evolution	NN
cord-024061-gxv8y146	30	21	of	of	IN
cord-024061-gxv8y146	30	22	animal	animal	NN
cord-024061-gxv8y146	30	23	viral	viral	JJ
cord-024061-gxv8y146	30	24	diseases	disease	NNS
cord-024061-gxv8y146	31	1	specially	specially	RB
cord-024061-gxv8y146	31	2	influenza	influenza	NN
cord-024061-gxv8y146	31	3	(	(	-LRB-
cord-024061-gxv8y146	31	4	20	20	CD
cord-024061-gxv8y146	31	5	)	)	-RRB-
cord-024061-gxv8y146	31	6	,	,	,
cord-024061-gxv8y146	31	7	FMD	FMD	NNP
cord-024061-gxv8y146	31	8	(	(	-LRB-
cord-024061-gxv8y146	31	9	17	17	CD
cord-024061-gxv8y146	31	10	)	)	-RRB-
cord-024061-gxv8y146	31	11	,	,	,
cord-024061-gxv8y146	31	12	and	and	CC
cord-024061-gxv8y146	31	13	PRRS	PRRS	NNP
cord-024061-gxv8y146	31	14	(	(	-LRB-
cord-024061-gxv8y146	31	15	21	21	CD
cord-024061-gxv8y146	31	16	)	)	-RRB-
cord-024061-gxv8y146	31	17	.	.	.
cord-024061-gxv8y146	32	1	Besides	besides	RB
cord-024061-gxv8y146	32	2	,	,	,
cord-024061-gxv8y146	32	3	several	several	JJ
cord-024061-gxv8y146	32	4	studies	study	NNS
cord-024061-gxv8y146	32	5	advocated	advocate	VBD
cord-024061-gxv8y146	32	6	for	for	IN
cord-024061-gxv8y146	32	7	the	the	DT
cord-024061-gxv8y146	32	8	integration	integration	NN
cord-024061-gxv8y146	32	9	of	of	IN
cord-024061-gxv8y146	32	10	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	32	11	methods	method	NNS
cord-024061-gxv8y146	32	12	in	in	IN
cord-024061-gxv8y146	32	13	the	the	DT
cord-024061-gxv8y146	32	14	routinely	routinely	RB
cord-024061-gxv8y146	32	15	molecular	molecular	JJ
cord-024061-gxv8y146	32	16	surveillance	surveillance	NN
cord-024061-gxv8y146	32	17	pipelines	pipeline	NNS
cord-024061-gxv8y146	32	18	of	of	IN
cord-024061-gxv8y146	32	19	animal	animal	NN
cord-024061-gxv8y146	32	20	diseases	disease	NNS
cord-024061-gxv8y146	32	21	with	with	IN
cord-024061-gxv8y146	32	22	the	the	DT
cord-024061-gxv8y146	32	23	objectives	objective	NNS
cord-024061-gxv8y146	32	24	of	of	IN
cord-024061-gxv8y146	32	25	reclassifying	reclassify	VBG
cord-024061-gxv8y146	32	26	viral	viral	JJ
cord-024061-gxv8y146	32	27	genotypes	genotype	NNS
cord-024061-gxv8y146	32	28	,	,	,
cord-024061-gxv8y146	32	29	distinguishing	distinguish	VBG
cord-024061-gxv8y146	32	30	between	between	IN
cord-024061-gxv8y146	32	31	emerging	emerge	VBG
cord-024061-gxv8y146	32	32	and	and	CC
cord-024061-gxv8y146	32	33	endemic	endemic	JJ
cord-024061-gxv8y146	32	34	viral	viral	JJ
cord-024061-gxv8y146	32	35	strains	strain	NNS
cord-024061-gxv8y146	32	36	,	,	,
cord-024061-gxv8y146	32	37	and	and	CC
cord-024061-gxv8y146	32	38	selecting	select	VBG
cord-024061-gxv8y146	32	39	proper	proper	JJ
cord-024061-gxv8y146	32	40	vaccine	vaccine	NN
cord-024061-gxv8y146	32	41	strains	strain	NNS
cord-024061-gxv8y146	32	42	(	(	-LRB-
cord-024061-gxv8y146	32	43	17	17	CD
cord-024061-gxv8y146	32	44	,	,	,
cord-024061-gxv8y146	32	45	(	(	-LRB-
cord-024061-gxv8y146	32	46	21	21	CD
cord-024061-gxv8y146	32	47	)	)	-RRB-
cord-024061-gxv8y146	32	48	(	(	-LRB-
cord-024061-gxv8y146	32	49	22	22	CD
cord-024061-gxv8y146	32	50	)	)	-RRB-
cord-024061-gxv8y146	32	51	(	(	-LRB-
cord-024061-gxv8y146	32	52	23	23	CD
cord-024061-gxv8y146	32	53	)	)	-RRB-
cord-024061-gxv8y146	32	54	.	.	.
cord-024061-gxv8y146	33	1	These	these	DT
cord-024061-gxv8y146	33	2	approaches	approach	NNS
cord-024061-gxv8y146	33	3	will	will	MD
cord-024061-gxv8y146	33	4	provide	provide	VB
cord-024061-gxv8y146	33	5	a	a	DT
cord-024061-gxv8y146	33	6	robust	robust	JJ
cord-024061-gxv8y146	33	7	platform	platform	NN
cord-024061-gxv8y146	33	8	for	for	IN
cord-024061-gxv8y146	33	9	guiding	guide	VBG
cord-024061-gxv8y146	33	10	the	the	DT
cord-024061-gxv8y146	33	11	allocation	allocation	NN
cord-024061-gxv8y146	33	12	of	of	IN
cord-024061-gxv8y146	33	13	resources	resource	NNS
cord-024061-gxv8y146	33	14	within	within	IN
cord-024061-gxv8y146	33	15	a	a	DT
cord-024061-gxv8y146	33	16	surveillance	surveillance	NN
cord-024061-gxv8y146	33	17	system	system	NN
cord-024061-gxv8y146	33	18	,	,	,
cord-024061-gxv8y146	33	19	for	for	IN
cord-024061-gxv8y146	33	20	example	example	NN
cord-024061-gxv8y146	33	21	,	,	,
cord-024061-gxv8y146	33	22	targeting	target	VBG
cord-024061-gxv8y146	33	23	emerging	emerge	VBG
cord-024061-gxv8y146	33	24	strains	strain	NNS
cord-024061-gxv8y146	33	25	with	with	IN
cord-024061-gxv8y146	33	26	higher	high	JJR
cord-024061-gxv8y146	33	27	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	33	28	rates	rate	NNS
cord-024061-gxv8y146	33	29	or	or	CC
cord-024061-gxv8y146	33	30	hosts	host	NNS
cord-024061-gxv8y146	33	31	at	at	IN
cord-024061-gxv8y146	33	32	high	high	JJ
cord-024061-gxv8y146	33	33	risk	risk	NN
cord-024061-gxv8y146	33	34	of	of	IN
cord-024061-gxv8y146	33	35	generating	generate	VBG
cord-024061-gxv8y146	33	36	new	new	JJ
cord-024061-gxv8y146	33	37	strains	strain	NNS
cord-024061-gxv8y146	33	38	,	,	,
cord-024061-gxv8y146	33	39	which	which	WDT
cord-024061-gxv8y146	33	40	subsequently	subsequently	RB
cord-024061-gxv8y146	33	41	will	will	MD
cord-024061-gxv8y146	33	42	reduce	reduce	VB
cord-024061-gxv8y146	33	43	the	the	DT
cord-024061-gxv8y146	33	44	economic	economic	JJ
cord-024061-gxv8y146	33	45	costs	cost	NNS
cord-024061-gxv8y146	33	46	of	of	IN
cord-024061-gxv8y146	33	47	sampling	sampling	NN
cord-024061-gxv8y146	33	48	,	,	,
cord-024061-gxv8y146	33	49	control	control	NN
cord-024061-gxv8y146	33	50	,	,	,
cord-024061-gxv8y146	33	51	and	and	CC
cord-024061-gxv8y146	33	52	prevention	prevention	NN
cord-024061-gxv8y146	33	53	activities	activity	NNS
cord-024061-gxv8y146	33	54	.	.	.
cord-024061-gxv8y146	34	1	Phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	34	2	methods	method	NNS
cord-024061-gxv8y146	34	3	are	be	VBP
cord-024061-gxv8y146	34	4	implemented	implement	VBN
cord-024061-gxv8y146	34	5	in	in	IN
cord-024061-gxv8y146	34	6	many	many	JJ
cord-024061-gxv8y146	34	7	open	open	JJ
cord-024061-gxv8y146	34	8	-	-	HYPH
cord-024061-gxv8y146	34	9	source	source	NN
cord-024061-gxv8y146	34	10	statistical	statistical	JJ
cord-024061-gxv8y146	34	11	software	software	NN
cord-024061-gxv8y146	34	12	packages	package	NNS
cord-024061-gxv8y146	34	13	,	,	,
cord-024061-gxv8y146	34	14	while	while	IN
cord-024061-gxv8y146	34	15	the	the	DT
cord-024061-gxv8y146	34	16	most	most	RBS
cord-024061-gxv8y146	34	17	popular	popular	JJ
cord-024061-gxv8y146	34	18	user	user	NN
cord-024061-gxv8y146	34	19	-	-	HYPH
cord-024061-gxv8y146	34	20	friendly	friendly	JJ
cord-024061-gxv8y146	34	21	software	software	NN
cord-024061-gxv8y146	34	22	package	package	NN
cord-024061-gxv8y146	34	23	is	be	VBZ
cord-024061-gxv8y146	34	24	formally	formally	RB
cord-024061-gxv8y146	34	25	known	know	VBN
cord-024061-gxv8y146	34	26	as	as	IN
cord-024061-gxv8y146	34	27	Bayesian	bayesian	JJ
cord-024061-gxv8y146	34	28	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	34	29	analysis	analysis	NN
cord-024061-gxv8y146	34	30	by	by	IN
cord-024061-gxv8y146	34	31	sampling	sampling	NN
cord-024061-gxv8y146	34	32	tree	tree	NN
cord-024061-gxv8y146	34	33	(	(	-LRB-
cord-024061-gxv8y146	34	34	BEAST	beast	NN
cord-024061-gxv8y146	34	35	)	)	-RRB-
cord-024061-gxv8y146	34	36	(	(	-LRB-
cord-024061-gxv8y146	34	37	24	24	CD
cord-024061-gxv8y146	34	38	)	)	-RRB-
cord-024061-gxv8y146	34	39	.	.	.
cord-024061-gxv8y146	35	1	While	while	IN
cord-024061-gxv8y146	35	2	past	past	JJ
cord-024061-gxv8y146	35	3	studies	study	NNS
cord-024061-gxv8y146	35	4	illustrated	illustrate	VBD
cord-024061-gxv8y146	35	5	the	the	DT
cord-024061-gxv8y146	35	6	great	great	JJ
cord-024061-gxv8y146	35	7	potential	potential	NN
cord-024061-gxv8y146	35	8	of	of	IN
cord-024061-gxv8y146	35	9	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	35	10	tools	tool	NNS
cord-024061-gxv8y146	35	11	,	,	,
cord-024061-gxv8y146	35	12	the	the	DT
cord-024061-gxv8y146	35	13	methods	method	NNS
cord-024061-gxv8y146	35	14	are	be	VBP
cord-024061-gxv8y146	35	15	sensitive	sensitive	JJ
cord-024061-gxv8y146	35	16	to	to	IN
cord-024061-gxv8y146	35	17	the	the	DT
cord-024061-gxv8y146	35	18	density	density	NN
cord-024061-gxv8y146	35	19	and	and	CC
cord-024061-gxv8y146	35	20	coverage	coverage	NN
cord-024061-gxv8y146	35	21	of	of	IN
cord-024061-gxv8y146	35	22	sequence	sequence	NN
cord-024061-gxv8y146	35	23	sampling	sampling	NN
cord-024061-gxv8y146	35	24	,	,	,
cord-024061-gxv8y146	35	25	selection	selection	NN
cord-024061-gxv8y146	35	26	of	of	IN
cord-024061-gxv8y146	35	27	genetic	genetic	JJ
cord-024061-gxv8y146	35	28	regions	region	NNS
cord-024061-gxv8y146	35	29	,	,	,
cord-024061-gxv8y146	35	30	quality	quality	NN
cord-024061-gxv8y146	35	31	and	and	CC
cord-024061-gxv8y146	35	32	quantity	quantity	NN
cord-024061-gxv8y146	35	33	of	of	IN
cord-024061-gxv8y146	35	34	the	the	DT
cord-024061-gxv8y146	35	35	associated	associate	VBN
cord-024061-gxv8y146	35	36	surveillance	surveillance	NN
cord-024061-gxv8y146	35	37	data	datum	NNS
cord-024061-gxv8y146	35	38	,	,	,
cord-024061-gxv8y146	35	39	and	and	CC
cord-024061-gxv8y146	35	40	prior	prior	JJ
cord-024061-gxv8y146	35	41	selection	selection	NN
cord-024061-gxv8y146	35	42	for	for	IN
cord-024061-gxv8y146	35	43	the	the	DT
cord-024061-gxv8y146	35	44	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	35	45	parameters	parameter	NNS
cord-024061-gxv8y146	35	46	(	(	-LRB-
cord-024061-gxv8y146	35	47	15	15	CD
cord-024061-gxv8y146	35	48	,	,	,
cord-024061-gxv8y146	35	49	25	25	CD
cord-024061-gxv8y146	35	50	,	,	,
cord-024061-gxv8y146	35	51	26	26	CD
cord-024061-gxv8y146	35	52	)	)	-RRB-
cord-024061-gxv8y146	35	53	.	.	.
cord-024061-gxv8y146	36	1	These	these	DT
cord-024061-gxv8y146	36	2	limitations	limitation	NNS
cord-024061-gxv8y146	36	3	may	may	MD
cord-024061-gxv8y146	36	4	result	result	VB
cord-024061-gxv8y146	36	5	in	in	IN
cord-024061-gxv8y146	36	6	biased	biased	JJ
cord-024061-gxv8y146	36	7	posterior	posterior	JJ
cord-024061-gxv8y146	36	8	inferences	inference	NNS
cord-024061-gxv8y146	36	9	,	,	,
cord-024061-gxv8y146	36	10	which	which	WDT
cord-024061-gxv8y146	36	11	subsequently	subsequently	RB
cord-024061-gxv8y146	36	12	lead	lead	VBP
cord-024061-gxv8y146	36	13	to	to	IN
cord-024061-gxv8y146	36	14	inaccurate	inaccurate	JJ
cord-024061-gxv8y146	36	15	or	or	CC
cord-024061-gxv8y146	36	16	biological	biological	JJ
cord-024061-gxv8y146	36	17	implausible	implausible	JJ
cord-024061-gxv8y146	36	18	conclusions	conclusion	NNS
cord-024061-gxv8y146	36	19	about	about	IN
cord-024061-gxv8y146	36	20	the	the	DT
cord-024061-gxv8y146	36	21	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	36	22	epidemiology	epidemiology	NN
cord-024061-gxv8y146	36	23	of	of	IN
cord-024061-gxv8y146	36	24	the	the	DT
cord-024061-gxv8y146	36	25	pathogen	pathogen	NN
cord-024061-gxv8y146	36	26	under	under	IN
cord-024061-gxv8y146	36	27	study	study	NN
cord-024061-gxv8y146	36	28	(	(	-LRB-
cord-024061-gxv8y146	36	29	e.g.	e.g.	RB
cord-024061-gxv8y146	36	30	,	,	,
cord-024061-gxv8y146	36	31	false	false	JJ
cord-024061-gxv8y146	36	32	divergence	divergence	NN
cord-024061-gxv8y146	36	33	time	time	NN
cord-024061-gxv8y146	36	34	or	or	CC
cord-024061-gxv8y146	36	35	geographical	geographical	JJ
cord-024061-gxv8y146	36	36	origins	origin	NNS
cord-024061-gxv8y146	36	37	)	)	-RRB-
cord-024061-gxv8y146	36	38	.	.	.
cord-024061-gxv8y146	37	1	That	that	DT
cord-024061-gxv8y146	37	2	said	say	VBD
cord-024061-gxv8y146	37	3	,	,	,
cord-024061-gxv8y146	37	4	most	most	JJS
cord-024061-gxv8y146	37	5	phylogenetic	phylogenetic	JJ
cord-024061-gxv8y146	37	6	studies	study	NNS
cord-024061-gxv8y146	37	7	suffer	suffer	VBP
cord-024061-gxv8y146	37	8	from	from	IN
cord-024061-gxv8y146	37	9	these	these	DT
cord-024061-gxv8y146	37	10	inherent	inherent	JJ
cord-024061-gxv8y146	37	11	limitations	limitation	NNS
cord-024061-gxv8y146	37	12	.	.	.
cord-024061-gxv8y146	38	1	However	however	RB
cord-024061-gxv8y146	38	2	,	,	,
cord-024061-gxv8y146	38	3	setting	set	VBG
cord-024061-gxv8y146	38	4	a	a	DT
cord-024061-gxv8y146	38	5	thorough	thorough	JJ
cord-024061-gxv8y146	38	6	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	38	7	analytical	analytical	JJ
cord-024061-gxv8y146	38	8	pipeline	pipeline	NN
cord-024061-gxv8y146	38	9	,	,	,
cord-024061-gxv8y146	38	10	while	while	IN
cord-024061-gxv8y146	38	11	acknowledging	acknowledge	VBG
cord-024061-gxv8y146	38	12	these	these	DT
cord-024061-gxv8y146	38	13	limitations	limitation	NNS
cord-024061-gxv8y146	38	14	,	,	,
cord-024061-gxv8y146	38	15	can	can	MD
cord-024061-gxv8y146	38	16	reduce	reduce	VB
cord-024061-gxv8y146	38	17	their	-PRON-	PRP$
cord-024061-gxv8y146	38	18	impact	impact	NN
cord-024061-gxv8y146	38	19	on	on	IN
cord-024061-gxv8y146	38	20	the	the	DT
cord-024061-gxv8y146	38	21	resulting	result	VBG
cord-024061-gxv8y146	38	22	posterior	posterior	JJ
cord-024061-gxv8y146	38	23	inferences	inference	NNS
cord-024061-gxv8y146	38	24	and	and	CC
cord-024061-gxv8y146	38	25	their	-PRON-	PRP$
cord-024061-gxv8y146	38	26	related	related	JJ
cord-024061-gxv8y146	38	27	conclusions	conclusion	NNS
cord-024061-gxv8y146	38	28	.	.	.
cord-024061-gxv8y146	39	1	Unfortunately	unfortunately	RB
cord-024061-gxv8y146	39	2	,	,	,
cord-024061-gxv8y146	39	3	many	many	JJ
cord-024061-gxv8y146	39	4	published	publish	VBN
cord-024061-gxv8y146	39	5	phylodynamic	phylodynamic	NNP
cord-024061-gxv8y146	39	6	studies	study	NNS
cord-024061-gxv8y146	39	7	ignored	ignore	VBD
cord-024061-gxv8y146	39	8	such	such	JJ
cord-024061-gxv8y146	39	9	limitations	limitation	NNS
cord-024061-gxv8y146	39	10	,	,	,
cord-024061-gxv8y146	39	11	particularly	particularly	RB
cord-024061-gxv8y146	39	12	in	in	IN
cord-024061-gxv8y146	39	13	their	-PRON-	PRP$
cord-024061-gxv8y146	39	14	analytical	analytical	JJ
cord-024061-gxv8y146	39	15	approach	approach	NN
cord-024061-gxv8y146	39	16	,	,	,
cord-024061-gxv8y146	39	17	in	in	IN
cord-024061-gxv8y146	39	18	which	which	WDT
cord-024061-gxv8y146	39	19	they	-PRON-	PRP
cord-024061-gxv8y146	39	20	used	use	VBD
cord-024061-gxv8y146	39	21	simple	simple	JJ
cord-024061-gxv8y146	39	22	naïve	naïve	JJ
cord-024061-gxv8y146	39	23	priors	prior	NNS
cord-024061-gxv8y146	39	24	for	for	IN
cord-024061-gxv8y146	39	25	their	-PRON-	PRP$
cord-024061-gxv8y146	39	26	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	39	27	parameters	parameter	NNS
cord-024061-gxv8y146	39	28	while	while	IN
cord-024061-gxv8y146	39	29	ignoring	ignore	VBG
cord-024061-gxv8y146	39	30	the	the	DT
cord-024061-gxv8y146	39	31	underlying	underlie	VBG
cord-024061-gxv8y146	39	32	assumptions	assumption	NNS
cord-024061-gxv8y146	39	33	for	for	IN
cord-024061-gxv8y146	39	34	these	these	DT
cord-024061-gxv8y146	39	35	priors	prior	NNS
cord-024061-gxv8y146	39	36	(	(	-LRB-
cord-024061-gxv8y146	39	37	27	27	CD
cord-024061-gxv8y146	39	38	)	)	-RRB-
cord-024061-gxv8y146	39	39	(	(	-LRB-
cord-024061-gxv8y146	39	40	28	28	CD
cord-024061-gxv8y146	39	41	)	)	-RRB-
cord-024061-gxv8y146	39	42	(	(	-LRB-
cord-024061-gxv8y146	39	43	29	29	CD
cord-024061-gxv8y146	39	44	)	)	-RRB-
cord-024061-gxv8y146	39	45	(	(	-LRB-
cord-024061-gxv8y146	39	46	30	30	CD
cord-024061-gxv8y146	39	47	)	)	-RRB-
cord-024061-gxv8y146	39	48	(	(	-LRB-
cord-024061-gxv8y146	39	49	31	31	CD
cord-024061-gxv8y146	39	50	)	)	-RRB-
cord-024061-gxv8y146	39	51	.	.	.
cord-024061-gxv8y146	40	1	For	for	IN
cord-024061-gxv8y146	40	2	example	example	NN
cord-024061-gxv8y146	40	3	,	,	,
cord-024061-gxv8y146	40	4	prior	prior	JJ
cord-024061-gxv8y146	40	5	selection	selection	NN
cord-024061-gxv8y146	40	6	should	should	MD
cord-024061-gxv8y146	40	7	adhere	adhere	VB
cord-024061-gxv8y146	40	8	to	to	IN
cord-024061-gxv8y146	40	9	the	the	DT
cord-024061-gxv8y146	40	10	assumption	assumption	NN
cord-024061-gxv8y146	40	11	that	that	IN
cord-024061-gxv8y146	40	12	different	different	JJ
cord-024061-gxv8y146	40	13	pathogens	pathogen	NNS
cord-024061-gxv8y146	40	14	have	have	VBP
cord-024061-gxv8y146	40	15	unique	unique	JJ
cord-024061-gxv8y146	40	16	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	40	17	characteristics	characteristic	NNS
cord-024061-gxv8y146	40	18	(	(	-LRB-
cord-024061-gxv8y146	40	19	14	14	CD
cord-024061-gxv8y146	40	20	)	)	-RRB-
cord-024061-gxv8y146	40	21	,	,	,
cord-024061-gxv8y146	40	22	and	and	CC
cord-024061-gxv8y146	40	23	therefore	therefore	RB
cord-024061-gxv8y146	40	24	,	,	,
cord-024061-gxv8y146	40	25	using	use	VBG
cord-024061-gxv8y146	40	26	the	the	DT
cord-024061-gxv8y146	40	27	same	same	JJ
cord-024061-gxv8y146	40	28	simple	simple	JJ
cord-024061-gxv8y146	40	29	prior	prior	RB
cord-024061-gxv8y146	40	30	on	on	IN
cord-024061-gxv8y146	40	31	different	different	JJ
cord-024061-gxv8y146	40	32	pathogens	pathogen	NNS
cord-024061-gxv8y146	40	33	will	will	MD
cord-024061-gxv8y146	40	34	likely	likely	RB
cord-024061-gxv8y146	40	35	lead	lead	VB
cord-024061-gxv8y146	40	36	to	to	IN
cord-024061-gxv8y146	40	37	the	the	DT
cord-024061-gxv8y146	40	38	conclusion	conclusion	NN
cord-024061-gxv8y146	40	39	that	that	IN
cord-024061-gxv8y146	40	40	such	such	JJ
cord-024061-gxv8y146	40	41	pathogens	pathogen	NNS
cord-024061-gxv8y146	40	42	behaved	behave	VBD
cord-024061-gxv8y146	40	43	similarly	similarly	RB
cord-024061-gxv8y146	40	44	during	during	IN
cord-024061-gxv8y146	40	45	their	-PRON-	PRP$
cord-024061-gxv8y146	40	46	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	40	47	history	history	NN
cord-024061-gxv8y146	40	48	.	.	.
cord-024061-gxv8y146	41	1	Also	also	RB
cord-024061-gxv8y146	41	2	,	,	,
cord-024061-gxv8y146	41	3	these	these	DT
cord-024061-gxv8y146	41	4	studies	study	NNS
cord-024061-gxv8y146	41	5	ignored	ignore	VBD
cord-024061-gxv8y146	41	6	the	the	DT
cord-024061-gxv8y146	41	7	impact	impact	NN
cord-024061-gxv8y146	41	8	of	of	IN
cord-024061-gxv8y146	41	9	selecting	select	VBG
cord-024061-gxv8y146	41	10	different	different	JJ
cord-024061-gxv8y146	41	11	prior	prior	JJ
cord-024061-gxv8y146	41	12	models	model	NNS
cord-024061-gxv8y146	41	13	on	on	IN
cord-024061-gxv8y146	41	14	their	-PRON-	PRP$
cord-024061-gxv8y146	41	15	posterior	posterior	JJ
cord-024061-gxv8y146	41	16	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	41	17	inferences	inference	NNS
cord-024061-gxv8y146	41	18	of	of	IN
cord-024061-gxv8y146	41	19	the	the	DT
cord-024061-gxv8y146	41	20	pathogen	pathogen	NN
cord-024061-gxv8y146	41	21	under	under	IN
cord-024061-gxv8y146	41	22	study	study	NN
cord-024061-gxv8y146	41	23	(	(	-LRB-
cord-024061-gxv8y146	41	24	26	26	CD
cord-024061-gxv8y146	41	25	,	,	,
cord-024061-gxv8y146	41	26	32	32	CD
cord-024061-gxv8y146	41	27	)	)	-RRB-
cord-024061-gxv8y146	41	28	.	.	.
cord-024061-gxv8y146	42	1	For	for	IN
cord-024061-gxv8y146	42	2	example	example	NN
cord-024061-gxv8y146	42	3	,	,	,
cord-024061-gxv8y146	42	4	the	the	DT
cord-024061-gxv8y146	42	5	use	use	NN
cord-024061-gxv8y146	42	6	of	of	IN
cord-024061-gxv8y146	42	7	different	different	JJ
cord-024061-gxv8y146	42	8	prior	prior	JJ
cord-024061-gxv8y146	42	9	models	model	NNS
cord-024061-gxv8y146	42	10	often	often	RB
cord-024061-gxv8y146	42	11	leads	lead	VBZ
cord-024061-gxv8y146	42	12	to	to	IN
cord-024061-gxv8y146	42	13	different	different	JJ
cord-024061-gxv8y146	42	14	conclusions	conclusion	NNS
cord-024061-gxv8y146	42	15	about	about	IN
cord-024061-gxv8y146	42	16	the	the	DT
cord-024061-gxv8y146	42	17	geographical	geographical	JJ
cord-024061-gxv8y146	42	18	origins	origin	NNS
cord-024061-gxv8y146	42	19	of	of	IN
cord-024061-gxv8y146	42	20	the	the	DT
cord-024061-gxv8y146	42	21	pathogen	pathogen	NN
cord-024061-gxv8y146	42	22	under	under	IN
cord-024061-gxv8y146	42	23	study	study	NN
cord-024061-gxv8y146	42	24	,	,	,
cord-024061-gxv8y146	42	25	and	and	CC
cord-024061-gxv8y146	42	26	hence	hence	RB
cord-024061-gxv8y146	42	27	,	,	,
cord-024061-gxv8y146	42	28	Bayesian	bayesian	JJ
cord-024061-gxv8y146	42	29	model	model	NN
cord-024061-gxv8y146	42	30	selection	selection	NN
cord-024061-gxv8y146	42	31	is	be	VBZ
cord-024061-gxv8y146	42	32	a	a	DT
cord-024061-gxv8y146	42	33	critical	critical	JJ
cord-024061-gxv8y146	42	34	step	step	NN
cord-024061-gxv8y146	42	35	in	in	IN
cord-024061-gxv8y146	42	36	phylodynamic	phylodynamic	NNP
cord-024061-gxv8y146	42	37	analysis	analysis	NN
cord-024061-gxv8y146	42	38	pipelines	pipeline	NNS
cord-024061-gxv8y146	42	39	(	(	-LRB-
cord-024061-gxv8y146	42	40	25	25	CD
cord-024061-gxv8y146	42	41	,	,	,
cord-024061-gxv8y146	42	42	33	33	CD
cord-024061-gxv8y146	42	43	)	)	-RRB-
cord-024061-gxv8y146	42	44	.	.	.
cord-024061-gxv8y146	43	1	There	there	EX
cord-024061-gxv8y146	43	2	are	be	VBP
cord-024061-gxv8y146	43	3	many	many	JJ
cord-024061-gxv8y146	43	4	studies	study	NNS
cord-024061-gxv8y146	43	5	in	in	IN
cord-024061-gxv8y146	43	6	the	the	DT
cord-024061-gxv8y146	43	7	published	publish	VBN
cord-024061-gxv8y146	43	8	literature	literature	NN
cord-024061-gxv8y146	43	9	comparing	compare	VBG
cord-024061-gxv8y146	43	10	the	the	DT
cord-024061-gxv8y146	43	11	results	result	NNS
cord-024061-gxv8y146	43	12	of	of	IN
cord-024061-gxv8y146	43	13	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	43	14	models	model	NNS
cord-024061-gxv8y146	43	15	inferred	infer	VBN
cord-024061-gxv8y146	43	16	from	from	IN
cord-024061-gxv8y146	43	17	different	different	JJ
cord-024061-gxv8y146	43	18	gene	gene	NN
cord-024061-gxv8y146	43	19	segments	segment	NNS
cord-024061-gxv8y146	43	20	or	or	CC
cord-024061-gxv8y146	43	21	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	43	22	parameters	parameter	NNS
cord-024061-gxv8y146	43	23	'	'	POS
cord-024061-gxv8y146	43	24	priors	prior	NNS
cord-024061-gxv8y146	43	25	(	(	-LRB-
cord-024061-gxv8y146	43	26	34	34	CD
cord-024061-gxv8y146	43	27	)	)	-RRB-
cord-024061-gxv8y146	43	28	(	(	-LRB-
cord-024061-gxv8y146	43	29	35	35	CD
cord-024061-gxv8y146	43	30	)	)	-RRB-
cord-024061-gxv8y146	43	31	(	(	-LRB-
cord-024061-gxv8y146	43	32	36	36	CD
cord-024061-gxv8y146	43	33	)	)	-RRB-
cord-024061-gxv8y146	43	34	.	.	.
cord-024061-gxv8y146	44	1	However	however	RB
cord-024061-gxv8y146	44	2	,	,	,
cord-024061-gxv8y146	44	3	few	few	JJ
cord-024061-gxv8y146	44	4	studies	study	NNS
cord-024061-gxv8y146	44	5	raised	raise	VBD
cord-024061-gxv8y146	44	6	concerns	concern	NNS
cord-024061-gxv8y146	44	7	about	about	IN
cord-024061-gxv8y146	44	8	the	the	DT
cord-024061-gxv8y146	44	9	sensitivity	sensitivity	NN
cord-024061-gxv8y146	44	10	of	of	IN
cord-024061-gxv8y146	44	11	the	the	DT
cord-024061-gxv8y146	44	12	results	result	NNS
cord-024061-gxv8y146	44	13	to	to	IN
cord-024061-gxv8y146	44	14	the	the	DT
cord-024061-gxv8y146	44	15	choice	choice	NN
cord-024061-gxv8y146	44	16	of	of	IN
cord-024061-gxv8y146	44	17	different	different	JJ
cord-024061-gxv8y146	44	18	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	44	19	models	model	NNS
cord-024061-gxv8y146	44	20	(	(	-LRB-
cord-024061-gxv8y146	44	21	20	20	CD
cord-024061-gxv8y146	44	22	,	,	,
cord-024061-gxv8y146	44	23	26	26	CD
cord-024061-gxv8y146	44	24	)	)	-RRB-
cord-024061-gxv8y146	44	25	as	as	RB
cord-024061-gxv8y146	44	26	well	well	RB
cord-024061-gxv8y146	44	27	as	as	IN
cord-024061-gxv8y146	44	28	suggested	suggest	VBD
cord-024061-gxv8y146	44	29	a	a	DT
cord-024061-gxv8y146	44	30	focused	focus	VBN
cord-024061-gxv8y146	44	31	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	44	32	analytical	analytical	JJ
cord-024061-gxv8y146	44	33	pipeline	pipeline	NN
cord-024061-gxv8y146	44	34	for	for	IN
cord-024061-gxv8y146	44	35	animal	animal	NN
cord-024061-gxv8y146	44	36	disease	disease	NN
cord-024061-gxv8y146	44	37	molecular	molecular	JJ
cord-024061-gxv8y146	44	38	surveillance	surveillance	NN
cord-024061-gxv8y146	44	39	(	(	-LRB-
cord-024061-gxv8y146	44	40	37	37	CD
cord-024061-gxv8y146	44	41	)	)	-RRB-
cord-024061-gxv8y146	44	42	.	.	.
cord-024061-gxv8y146	45	1	Here	here	RB
cord-024061-gxv8y146	45	2	,	,	,
cord-024061-gxv8y146	45	3	we	-PRON-	PRP
cord-024061-gxv8y146	45	4	demonstrate	demonstrate	VBP
cord-024061-gxv8y146	45	5	the	the	DT
cord-024061-gxv8y146	45	6	basic	basic	JJ
cord-024061-gxv8y146	45	7	principles	principle	NNS
cord-024061-gxv8y146	45	8	for	for	IN
cord-024061-gxv8y146	45	9	building	build	VBG
cord-024061-gxv8y146	45	10	a	a	DT
cord-024061-gxv8y146	45	11	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	45	12	analytical	analytical	JJ
cord-024061-gxv8y146	45	13	pipeline	pipeline	NN
cord-024061-gxv8y146	45	14	,	,	,
cord-024061-gxv8y146	45	15	illustrate	illustrate	VBP
cord-024061-gxv8y146	45	16	examples	example	NNS
cord-024061-gxv8y146	45	17	on	on	IN
cord-024061-gxv8y146	45	18	the	the	DT
cord-024061-gxv8y146	45	19	impact	impact	NN
cord-024061-gxv8y146	45	20	of	of	IN
cord-024061-gxv8y146	45	21	gene	gene	NN
cord-024061-gxv8y146	45	22	segment	segment	NN
cord-024061-gxv8y146	45	23	and	and	CC
cord-024061-gxv8y146	45	24	prior	prior	JJ
cord-024061-gxv8y146	45	25	selection	selection	NN
cord-024061-gxv8y146	45	26	on	on	IN
cord-024061-gxv8y146	45	27	the	the	DT
cord-024061-gxv8y146	45	28	posterior	posterior	JJ
cord-024061-gxv8y146	45	29	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	45	30	inferences	inference	NNS
cord-024061-gxv8y146	45	31	,	,	,
cord-024061-gxv8y146	45	32	and	and	CC
cord-024061-gxv8y146	45	33	highlight	highlight	VB
cord-024061-gxv8y146	45	34	the	the	DT
cord-024061-gxv8y146	45	35	prospects	prospect	NNS
cord-024061-gxv8y146	45	36	of	of	IN
cord-024061-gxv8y146	45	37	the	the	DT
cord-024061-gxv8y146	45	38	methods	method	NNS
cord-024061-gxv8y146	45	39	in	in	IN
cord-024061-gxv8y146	45	40	improving	improve	VBG
cord-024061-gxv8y146	45	41	animal	animal	NN
cord-024061-gxv8y146	45	42	disease	disease	NN
cord-024061-gxv8y146	45	43	surveillance	surveillance	NN
cord-024061-gxv8y146	45	44	.	.	.
cord-024061-gxv8y146	46	1	We	-PRON-	PRP
cord-024061-gxv8y146	46	2	selected	select	VBD
cord-024061-gxv8y146	46	3	a	a	DT
cord-024061-gxv8y146	46	4	publicly	publicly	RB
cord-024061-gxv8y146	46	5	available	available	JJ
cord-024061-gxv8y146	46	6	dataset	dataset	NN
cord-024061-gxv8y146	46	7	compromising	compromising	NN
cord-024061-gxv8y146	46	8	of	of	IN
cord-024061-gxv8y146	46	9	352	352	CD
cord-024061-gxv8y146	46	10	full	full	JJ
cord-024061-gxv8y146	46	11	genome	genome	NN
cord-024061-gxv8y146	46	12	sequences	sequence	NNS
cord-024061-gxv8y146	46	13	for	for	IN
cord-024061-gxv8y146	46	14	human	human	NN
cord-024061-gxv8y146	46	15	-	-	HYPH
cord-024061-gxv8y146	46	16	like	like	JJ
cord-024061-gxv8y146	46	17	H3	H3	NNP
cord-024061-gxv8y146	46	18	swine	swine	NN
cord-024061-gxv8y146	46	19	SI	si	NN
cord-024061-gxv8y146	46	20	collected	collect	VBN
cord-024061-gxv8y146	46	21	as	as	IN
cord-024061-gxv8y146	46	22	part	part	NN
cord-024061-gxv8y146	46	23	of	of	IN
cord-024061-gxv8y146	46	24	the	the	DT
cord-024061-gxv8y146	46	25	United	United	NNP
cord-024061-gxv8y146	46	26	States	States	NNP
cord-024061-gxv8y146	46	27	Department	Department	NNP
cord-024061-gxv8y146	46	28	of	of	IN
cord-024061-gxv8y146	46	29	Agriculture	Agriculture	NNP
cord-024061-gxv8y146	46	30	influenza	influenza	NN
cord-024061-gxv8y146	46	31	surveillance	surveillance	NN
cord-024061-gxv8y146	46	32	system	system	NN
cord-024061-gxv8y146	46	33	between	between	IN
cord-024061-gxv8y146	46	34	2015	2015	CD
cord-024061-gxv8y146	46	35	and	and	CC
cord-024061-gxv8y146	46	36	2018	2018	CD
cord-024061-gxv8y146	46	37	as	as	IN
cord-024061-gxv8y146	46	38	a	a	DT
cord-024061-gxv8y146	46	39	working	work	VBG
cord-024061-gxv8y146	46	40	example	example	NN
cord-024061-gxv8y146	46	41	.	.	.
cord-024061-gxv8y146	47	1	We	-PRON-	PRP
cord-024061-gxv8y146	47	2	provided	provide	VBD
cord-024061-gxv8y146	47	3	a	a	DT
cord-024061-gxv8y146	47	4	detailed	detailed	JJ
cord-024061-gxv8y146	47	5	description	description	NN
cord-024061-gxv8y146	47	6	of	of	IN
cord-024061-gxv8y146	47	7	a	a	DT
cord-024061-gxv8y146	47	8	classical	classical	JJ
cord-024061-gxv8y146	47	9	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	47	10	analytical	analytical	JJ
cord-024061-gxv8y146	47	11	pipeline	pipeline	NN
cord-024061-gxv8y146	47	12	encompassing	encompass	VBG
cord-024061-gxv8y146	47	13	both	both	CC
cord-024061-gxv8y146	47	14	demographic	demographic	JJ
cord-024061-gxv8y146	47	15	and	and	CC
cord-024061-gxv8y146	47	16	discrete	discrete	JJ
cord-024061-gxv8y146	47	17	phylogeographic	phylogeographic	JJ
cord-024061-gxv8y146	47	18	reconstruction	reconstruction	NN
cord-024061-gxv8y146	47	19	of	of	IN
cord-024061-gxv8y146	47	20	the	the	DT
cord-024061-gxv8y146	47	21	human	human	NN
cord-024061-gxv8y146	47	22	-	-	HYPH
cord-024061-gxv8y146	47	23	like	like	JJ
cord-024061-gxv8y146	47	24	H3	H3	NNP
cord-024061-gxv8y146	47	25	virus	virus	NN
cord-024061-gxv8y146	47	26	using	use	VBG
cord-024061-gxv8y146	47	27	BEAST	BEAST	NNP
cord-024061-gxv8y146	47	28	.	.	.
cord-024061-gxv8y146	48	1	Our	-PRON-	PRP$
cord-024061-gxv8y146	48	2	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	48	3	analyses	analysis	NNS
cord-024061-gxv8y146	48	4	included	include	VBD
cord-024061-gxv8y146	48	5	comparisons	comparison	NNS
cord-024061-gxv8y146	48	6	between	between	IN
cord-024061-gxv8y146	48	7	commonly	commonly	RB
cord-024061-gxv8y146	48	8	inferred	infer	VBN
cord-024061-gxv8y146	48	9	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	48	10	posterior	posterior	JJ
cord-024061-gxv8y146	48	11	parameters	parameter	NNS
cord-024061-gxv8y146	48	12	(	(	-LRB-
cord-024061-gxv8y146	48	13	e.g.	e.g.	RB
cord-024061-gxv8y146	48	14	,	,	,
cord-024061-gxv8y146	48	15	substitution	substitution	NN
cord-024061-gxv8y146	48	16	rate	rate	NN
cord-024061-gxv8y146	48	17	/	/	SYM
cord-024061-gxv8y146	48	18	site	site	NN
cord-024061-gxv8y146	48	19	/	/	SYM
cord-024061-gxv8y146	48	20	year	year	NN
cord-024061-gxv8y146	48	21	,	,	,
cord-024061-gxv8y146	48	22	divergence	divergence	NN
cord-024061-gxv8y146	48	23	times	time	NNS
cord-024061-gxv8y146	48	24	,	,	,
cord-024061-gxv8y146	48	25	phylogeographic	phylogeographic	JJ
cord-024061-gxv8y146	48	26	root	root	NN
cord-024061-gxv8y146	48	27	state	state	NN
cord-024061-gxv8y146	48	28	posterior	posterior	JJ
cord-024061-gxv8y146	48	29	probabilities	probability	NNS
cord-024061-gxv8y146	48	30	,	,	,
cord-024061-gxv8y146	48	31	significant	significant	JJ
cord-024061-gxv8y146	48	32	dispersal	dispersal	NN
cord-024061-gxv8y146	48	33	route	route	NN
cord-024061-gxv8y146	48	34	between	between	IN
cord-024061-gxv8y146	48	35	states	state	NNS
cord-024061-gxv8y146	48	36	)	)	-RRB-
cord-024061-gxv8y146	48	37	under	under	IN
cord-024061-gxv8y146	48	38	different	different	JJ
cord-024061-gxv8y146	48	39	combinations	combination	NNS
cord-024061-gxv8y146	48	40	of	of	IN
cord-024061-gxv8y146	48	41	node	node	NN
cord-024061-gxv8y146	48	42	-	-	HYPH
cord-024061-gxv8y146	48	43	age	age	NN
cord-024061-gxv8y146	48	44	and	and	CC
cord-024061-gxv8y146	48	45	branch	branch	NN
cord-024061-gxv8y146	48	46	rate	rate	NN
cord-024061-gxv8y146	48	47	prior	prior	JJ
cord-024061-gxv8y146	48	48	models	model	NNS
cord-024061-gxv8y146	48	49	.	.	.
cord-024061-gxv8y146	49	1	Furthermore	furthermore	RB
cord-024061-gxv8y146	49	2	,	,	,
cord-024061-gxv8y146	49	3	we	-PRON-	PRP
cord-024061-gxv8y146	49	4	extended	extend	VBD
cord-024061-gxv8y146	49	5	this	this	DT
cord-024061-gxv8y146	49	6	analytical	analytical	JJ
cord-024061-gxv8y146	49	7	pipeline	pipeline	NN
cord-024061-gxv8y146	49	8	into	into	IN
cord-024061-gxv8y146	49	9	comparing	compare	VBG
cord-024061-gxv8y146	49	10	posterior	posterior	JJ
cord-024061-gxv8y146	49	11	parameters	parameter	NNS
cord-024061-gxv8y146	49	12	inferred	infer	VBN
cord-024061-gxv8y146	49	13	from	from	IN
cord-024061-gxv8y146	49	14	HA	HA	NNP
cord-024061-gxv8y146	49	15	and	and	CC
cord-024061-gxv8y146	49	16	PB2	PB2	NNP
cord-024061-gxv8y146	49	17	gene	gene	NN
cord-024061-gxv8y146	49	18	segments	segment	NNS
cord-024061-gxv8y146	49	19	.	.	.
cord-024061-gxv8y146	50	1	Interpretation	interpretation	NN
cord-024061-gxv8y146	50	2	of	of	IN
cord-024061-gxv8y146	50	3	the	the	DT
cord-024061-gxv8y146	50	4	resulting	result	VBG
cord-024061-gxv8y146	50	5	posterior	posterior	JJ
cord-024061-gxv8y146	50	6	inferences	inference	NNS
cord-024061-gxv8y146	50	7	under	under	IN
cord-024061-gxv8y146	50	8	different	different	JJ
cord-024061-gxv8y146	50	9	scenarios	scenario	NNS
cord-024061-gxv8y146	50	10	,	,	,
cord-024061-gxv8y146	50	11	described	describe	VBN
cord-024061-gxv8y146	50	12	above	above	RB
cord-024061-gxv8y146	50	13	,	,	,
cord-024061-gxv8y146	50	14	has	have	VBZ
cord-024061-gxv8y146	50	15	been	be	VBN
cord-024061-gxv8y146	50	16	discussed	discuss	VBN
cord-024061-gxv8y146	50	17	in	in	IN
cord-024061-gxv8y146	50	18	detail	detail	NN
cord-024061-gxv8y146	50	19	,	,	,
cord-024061-gxv8y146	50	20	and	and	CC
cord-024061-gxv8y146	50	21	we	-PRON-	PRP
cord-024061-gxv8y146	50	22	highlighted	highlight	VBD
cord-024061-gxv8y146	50	23	examples	example	NNS
cord-024061-gxv8y146	50	24	of	of	IN
cord-024061-gxv8y146	50	25	their	-PRON-	PRP$
cord-024061-gxv8y146	50	26	misuse	misuse	NN
cord-024061-gxv8y146	50	27	in	in	IN
cord-024061-gxv8y146	50	28	past	past	JJ
cord-024061-gxv8y146	50	29	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	50	30	studies	study	NNS
cord-024061-gxv8y146	50	31	.	.	.
cord-024061-gxv8y146	51	1	Our	-PRON-	PRP$
cord-024061-gxv8y146	51	2	results	result	NNS
cord-024061-gxv8y146	51	3	identified	identify	VBD
cord-024061-gxv8y146	51	4	the	the	DT
cord-024061-gxv8y146	51	5	prospects	prospect	NNS
cord-024061-gxv8y146	51	6	and	and	CC
cord-024061-gxv8y146	51	7	limitations	limitation	NNS
cord-024061-gxv8y146	51	8	of	of	IN
cord-024061-gxv8y146	51	9	the	the	DT
cord-024061-gxv8y146	51	10	presented	present	VBN
cord-024061-gxv8y146	51	11	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	51	12	pipeline	pipeline	NN
cord-024061-gxv8y146	51	13	in	in	IN
cord-024061-gxv8y146	51	14	the	the	DT
cord-024061-gxv8y146	51	15	context	context	NN
cord-024061-gxv8y146	51	16	of	of	IN
cord-024061-gxv8y146	51	17	animal	animal	NN
cord-024061-gxv8y146	51	18	disease	disease	NN
cord-024061-gxv8y146	51	19	surveillance	surveillance	NN
cord-024061-gxv8y146	51	20	on	on	IN
cord-024061-gxv8y146	51	21	regional	regional	JJ
cord-024061-gxv8y146	51	22	and	and	CC
cord-024061-gxv8y146	51	23	global	global	JJ
cord-024061-gxv8y146	51	24	scales	scale	NNS
cord-024061-gxv8y146	51	25	.	.	.
cord-024061-gxv8y146	52	1	Furthermore	furthermore	RB
cord-024061-gxv8y146	52	2	,	,	,
cord-024061-gxv8y146	52	3	our	-PRON-	PRP$
cord-024061-gxv8y146	52	4	results	result	NNS
cord-024061-gxv8y146	52	5	provide	provide	VBP
cord-024061-gxv8y146	52	6	researchers	researcher	NNS
cord-024061-gxv8y146	52	7	and	and	CC
cord-024061-gxv8y146	52	8	stakeholders	stakeholder	NNS
cord-024061-gxv8y146	52	9	of	of	IN
cord-024061-gxv8y146	52	10	the	the	DT
cord-024061-gxv8y146	52	11	swine	swine	NN
cord-024061-gxv8y146	52	12	industry	industry	NN
cord-024061-gxv8y146	52	13	in	in	IN
cord-024061-gxv8y146	52	14	the	the	DT
cord-024061-gxv8y146	52	15	United	United	NNP
cord-024061-gxv8y146	52	16	States	States	NNP
cord-024061-gxv8y146	52	17	valuable	valuable	JJ
cord-024061-gxv8y146	52	18	insights	insight	NNS
cord-024061-gxv8y146	52	19	on	on	IN
cord-024061-gxv8y146	52	20	decisions	decision	NNS
cord-024061-gxv8y146	52	21	related	relate	VBN
cord-024061-gxv8y146	52	22	to	to	IN
cord-024061-gxv8y146	52	23	the	the	DT
cord-024061-gxv8y146	52	24	sampling	sampling	NN
cord-024061-gxv8y146	52	25	and	and	CC
cord-024061-gxv8y146	52	26	sequencing	sequencing	NN
cord-024061-gxv8y146	52	27	of	of	IN
cord-024061-gxv8y146	52	28	the	the	DT
cord-024061-gxv8y146	52	29	influenza	influenza	NN
cord-024061-gxv8y146	52	30	virus	virus	NN
cord-024061-gxv8y146	52	31	genome	genome	NN
cord-024061-gxv8y146	52	32	when	when	WRB
cord-024061-gxv8y146	52	33	conducting	conduct	VBG
cord-024061-gxv8y146	52	34	future	future	JJ
cord-024061-gxv8y146	52	35	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	52	36	studies	study	NNS
cord-024061-gxv8y146	52	37	and	and	CC
cord-024061-gxv8y146	52	38	improving	improve	VBG
cord-024061-gxv8y146	52	39	the	the	DT
cord-024061-gxv8y146	52	40	design	design	NN
cord-024061-gxv8y146	52	41	of	of	IN
cord-024061-gxv8y146	52	42	currently	currently	RB
cord-024061-gxv8y146	52	43	implemented	implement	VBN
cord-024061-gxv8y146	52	44	surveillance	surveillance	NN
cord-024061-gxv8y146	52	45	systems	system	NNS
cord-024061-gxv8y146	52	46	.	.	.
cord-024061-gxv8y146	53	1	The	the	DT
cord-024061-gxv8y146	53	2	summary	summary	NN
cord-024061-gxv8y146	53	3	flow	flow	NN
cord-024061-gxv8y146	53	4	chart	chart	NN
cord-024061-gxv8y146	53	5	of	of	IN
cord-024061-gxv8y146	53	6	our	-PRON-	PRP$
cord-024061-gxv8y146	53	7	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	53	8	analytical	analytical	JJ
cord-024061-gxv8y146	53	9	pipeline	pipeline	NN
cord-024061-gxv8y146	53	10	is	be	VBZ
cord-024061-gxv8y146	53	11	presented	present	VBN
cord-024061-gxv8y146	53	12	in	in	IN
cord-024061-gxv8y146	53	13	Figure	figure	NN
cord-024061-gxv8y146	53	14	1	1	CD
cord-024061-gxv8y146	53	15	.	.	.
cord-024061-gxv8y146	54	1	This	this	DT
cord-024061-gxv8y146	54	2	Bayesian	bayesian	JJ
cord-024061-gxv8y146	54	3	statistical	statistical	JJ
cord-024061-gxv8y146	54	4	framework	framework	NN
cord-024061-gxv8y146	54	5	is	be	VBZ
cord-024061-gxv8y146	54	6	popular	popular	JJ
cord-024061-gxv8y146	54	7	and	and	CC
cord-024061-gxv8y146	54	8	well	well	RB
cord-024061-gxv8y146	54	9	-	-	HYPH
cord-024061-gxv8y146	54	10	established	establish	VBN
cord-024061-gxv8y146	54	11	for	for	IN
cord-024061-gxv8y146	54	12	studying	study	VBG
cord-024061-gxv8y146	54	13	rapidly	rapidly	RB
cord-024061-gxv8y146	54	14	evolving	evolve	VBG
cord-024061-gxv8y146	54	15	pathogens	pathogen	NNS
cord-024061-gxv8y146	54	16	as	as	IN
cord-024061-gxv8y146	54	17	described	describe	VBN
cord-024061-gxv8y146	54	18	elsewhere	elsewhere	RB
cord-024061-gxv8y146	54	19	(	(	-LRB-
cord-024061-gxv8y146	54	20	37	37	CD
cord-024061-gxv8y146	54	21	)	)	-RRB-
cord-024061-gxv8y146	54	22	(	(	-LRB-
cord-024061-gxv8y146	54	23	38	38	CD
cord-024061-gxv8y146	54	24	)	)	-RRB-
cord-024061-gxv8y146	54	25	(	(	-LRB-
cord-024061-gxv8y146	54	26	39	39	CD
cord-024061-gxv8y146	54	27	)	)	-RRB-
cord-024061-gxv8y146	54	28	.	.	.
cord-024061-gxv8y146	55	1	The	the	DT
cord-024061-gxv8y146	55	2	pipeline	pipeline	NN
cord-024061-gxv8y146	55	3	is	be	VBZ
cord-024061-gxv8y146	55	4	divided	divide	VBN
cord-024061-gxv8y146	55	5	into	into	IN
cord-024061-gxv8y146	55	6	five	five	CD
cord-024061-gxv8y146	55	7	steps	step	NNS
cord-024061-gxv8y146	55	8	(	(	-LRB-
cord-024061-gxv8y146	55	9	Figure	figure	NN
cord-024061-gxv8y146	55	10	1	1	CD
cord-024061-gxv8y146	55	11	)	)	-RRB-
cord-024061-gxv8y146	55	12	,	,	,
cord-024061-gxv8y146	55	13	in	in	IN
cord-024061-gxv8y146	55	14	which	which	WDT
cord-024061-gxv8y146	55	15	two	two	CD
cord-024061-gxv8y146	55	16	steps	step	NNS
cord-024061-gxv8y146	55	17	are	be	VBP
cord-024061-gxv8y146	55	18	dedicated	dedicate	VBN
cord-024061-gxv8y146	55	19	to	to	TO
cord-024061-gxv8y146	55	20	sequence	sequence	VB
cord-024061-gxv8y146	55	21	preparation	preparation	NN
cord-024061-gxv8y146	55	22	and	and	CC
cord-024061-gxv8y146	55	23	curation	curation	NN
cord-024061-gxv8y146	55	24	of	of	IN
cord-024061-gxv8y146	55	25	relevant	relevant	JJ
cord-024061-gxv8y146	55	26	viral	viral	JJ
cord-024061-gxv8y146	55	27	lineages	lineage	NNS
cord-024061-gxv8y146	55	28	,	,	,
cord-024061-gxv8y146	55	29	while	while	IN
cord-024061-gxv8y146	55	30	the	the	DT
cord-024061-gxv8y146	55	31	following	follow	VBG
cord-024061-gxv8y146	55	32	three	three	CD
cord-024061-gxv8y146	55	33	steps	step	NNS
cord-024061-gxv8y146	55	34	are	be	VBP
cord-024061-gxv8y146	55	35	dedicated	dedicate	VBN
cord-024061-gxv8y146	55	36	for	for	IN
cord-024061-gxv8y146	55	37	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	55	38	analyses	analysis	NNS
cord-024061-gxv8y146	55	39	of	of	IN
cord-024061-gxv8y146	55	40	the	the	DT
cord-024061-gxv8y146	55	41	subsequently	subsequently	RB
cord-024061-gxv8y146	55	42	selected	select	VBN
cord-024061-gxv8y146	55	43	lineages	lineage	NNS
cord-024061-gxv8y146	55	44	.	.	.
cord-024061-gxv8y146	56	1	A	a	DT
cord-024061-gxv8y146	56	2	critical	critical	JJ
cord-024061-gxv8y146	56	3	step	step	NN
cord-024061-gxv8y146	56	4	for	for	IN
cord-024061-gxv8y146	56	5	a	a	DT
cord-024061-gxv8y146	56	6	sound	sound	JJ
cord-024061-gxv8y146	56	7	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	56	8	analysis	analysis	NN
cord-024061-gxv8y146	56	9	is	be	VBZ
cord-024061-gxv8y146	56	10	sequence	sequence	NN
cord-024061-gxv8y146	56	11	preparation	preparation	NN
cord-024061-gxv8y146	56	12	.	.	.
cord-024061-gxv8y146	57	1	This	this	DT
cord-024061-gxv8y146	57	2	step	step	NN
cord-024061-gxv8y146	57	3	can	can	MD
cord-024061-gxv8y146	57	4	take	take	VB
cord-024061-gxv8y146	57	5	two	two	CD
cord-024061-gxv8y146	57	6	directions	direction	NNS
cord-024061-gxv8y146	57	7	,	,	,
cord-024061-gxv8y146	57	8	depending	depend	VBG
cord-024061-gxv8y146	57	9	on	on	IN
cord-024061-gxv8y146	57	10	the	the	DT
cord-024061-gxv8y146	57	11	study	study	NN
cord-024061-gxv8y146	57	12	design	design	NN
cord-024061-gxv8y146	57	13	and	and	CC
cord-024061-gxv8y146	57	14	the	the	DT
cord-024061-gxv8y146	57	15	objectives	objective	NNS
cord-024061-gxv8y146	57	16	of	of	IN
cord-024061-gxv8y146	57	17	the	the	DT
cord-024061-gxv8y146	57	18	analysis	analysis	NN
cord-024061-gxv8y146	57	19	.	.	.
cord-024061-gxv8y146	58	1	The	the	DT
cord-024061-gxv8y146	58	2	first	first	JJ
cord-024061-gxv8y146	58	3	direction	direction	NN
cord-024061-gxv8y146	58	4	involves	involve	VBZ
cord-024061-gxv8y146	58	5	primary	primary	JJ
cord-024061-gxv8y146	58	6	data	data	NN
cord-024061-gxv8y146	58	7	analyses	analysis	NNS
cord-024061-gxv8y146	58	8	of	of	IN
cord-024061-gxv8y146	58	9	novel	novel	NN
cord-024061-gxv8y146	58	10	sequences	sequence	NNS
cord-024061-gxv8y146	58	11	,	,	,
cord-024061-gxv8y146	58	12	in	in	IN
cord-024061-gxv8y146	58	13	which	which	WDT
cord-024061-gxv8y146	58	14	they	-PRON-	PRP
cord-024061-gxv8y146	58	15	are	be	VBP
cord-024061-gxv8y146	58	16	either	either	DT
cord-024061-gxv8y146	58	17	part	part	NN
cord-024061-gxv8y146	58	18	of	of	IN
cord-024061-gxv8y146	58	19	a	a	DT
cord-024061-gxv8y146	58	20	designed	design	VBN
cord-024061-gxv8y146	58	21	study	study	NN
cord-024061-gxv8y146	58	22	to	to	TO
cord-024061-gxv8y146	58	23	identify	identify	VB
cord-024061-gxv8y146	58	24	the	the	DT
cord-024061-gxv8y146	58	25	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	58	26	characteristics	characteristic	NNS
cord-024061-gxv8y146	58	27	of	of	IN
cord-024061-gxv8y146	58	28	newly	newly	RB
cord-024061-gxv8y146	58	29	emerging	emerge	VBG
cord-024061-gxv8y146	58	30	viral	viral	JJ
cord-024061-gxv8y146	58	31	strains	strain	NNS
cord-024061-gxv8y146	58	32	(	(	-LRB-
cord-024061-gxv8y146	58	33	27	27	CD
cord-024061-gxv8y146	58	34	,	,	,
cord-024061-gxv8y146	58	35	37	37	CD
cord-024061-gxv8y146	58	36	,	,	,
cord-024061-gxv8y146	58	37	39	39	CD
cord-024061-gxv8y146	58	38	)	)	-RRB-
cord-024061-gxv8y146	58	39	or	or	CC
cord-024061-gxv8y146	58	40	part	part	NN
cord-024061-gxv8y146	58	41	of	of	IN
cord-024061-gxv8y146	58	42	an	an	DT
cord-024061-gxv8y146	58	43	ongoing	ongoing	JJ
cord-024061-gxv8y146	58	44	active	active	JJ
cord-024061-gxv8y146	58	45	surveillance	surveillance	NN
cord-024061-gxv8y146	58	46	program	program	NN
cord-024061-gxv8y146	58	47	(	(	-LRB-
cord-024061-gxv8y146	58	48	40	40	CD
cord-024061-gxv8y146	58	49	)	)	-RRB-
cord-024061-gxv8y146	58	50	.	.	.
cord-024061-gxv8y146	59	1	This	this	DT
cord-024061-gxv8y146	59	2	direction	direction	NN
cord-024061-gxv8y146	59	3	usually	usually	RB
cord-024061-gxv8y146	59	4	includes	include	VBZ
cord-024061-gxv8y146	59	5	the	the	DT
cord-024061-gxv8y146	59	6	collection	collection	NN
cord-024061-gxv8y146	59	7	and	and	CC
cord-024061-gxv8y146	59	8	sequencing	sequencing	NN
cord-024061-gxv8y146	59	9	of	of	IN
cord-024061-gxv8y146	59	10	novel	novel	JJ
cord-024061-gxv8y146	59	11	viral	viral	JJ
cord-024061-gxv8y146	59	12	isolates	isolate	NNS
cord-024061-gxv8y146	59	13	from	from	IN
cord-024061-gxv8y146	59	14	ongoing	ongoing	JJ
cord-024061-gxv8y146	59	15	outbreaks	outbreak	NNS
cord-024061-gxv8y146	59	16	.	.	.
cord-024061-gxv8y146	60	1	The	the	DT
cord-024061-gxv8y146	60	2	second	second	JJ
cord-024061-gxv8y146	60	3	direction	direction	NN
cord-024061-gxv8y146	60	4	involves	involve	VBZ
cord-024061-gxv8y146	60	5	secondary	secondary	JJ
cord-024061-gxv8y146	60	6	data	data	NN
cord-024061-gxv8y146	60	7	analyses	analysis	NNS
cord-024061-gxv8y146	60	8	of	of	IN
cord-024061-gxv8y146	60	9	sequence	sequence	NN
cord-024061-gxv8y146	60	10	collections	collection	NNS
cord-024061-gxv8y146	60	11	published	publish	VBN
cord-024061-gxv8y146	60	12	in	in	IN
cord-024061-gxv8y146	60	13	publicly	publicly	RB
cord-024061-gxv8y146	60	14	available	available	JJ
cord-024061-gxv8y146	60	15	genomic	genomic	JJ
cord-024061-gxv8y146	60	16	databases	database	NNS
cord-024061-gxv8y146	60	17	such	such	JJ
cord-024061-gxv8y146	60	18	as	as	IN
cord-024061-gxv8y146	60	19	the	the	DT
cord-024061-gxv8y146	60	20	Genbank	Genbank	NNP
cord-024061-gxv8y146	60	21	,	,	,
cord-024061-gxv8y146	60	22	to	to	TO
cord-024061-gxv8y146	60	23	mainly	mainly	RB
cord-024061-gxv8y146	60	24	explore	explore	VB
cord-024061-gxv8y146	60	25	the	the	DT
cord-024061-gxv8y146	60	26	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	60	27	history	history	NN
cord-024061-gxv8y146	60	28	of	of	IN
cord-024061-gxv8y146	60	29	specific	specific	JJ
cord-024061-gxv8y146	60	30	pathogens	pathogen	NNS
cord-024061-gxv8y146	60	31	either	either	CC
cord-024061-gxv8y146	60	32	on	on	IN
cord-024061-gxv8y146	60	33	regional	regional	JJ
cord-024061-gxv8y146	60	34	or	or	CC
cord-024061-gxv8y146	60	35	global	global	JJ
cord-024061-gxv8y146	60	36	scales	scale	NNS
cord-024061-gxv8y146	60	37	(	(	-LRB-
cord-024061-gxv8y146	60	38	38	38	CD
cord-024061-gxv8y146	60	39	,	,	,
cord-024061-gxv8y146	60	40	41	41	CD
cord-024061-gxv8y146	60	41	,	,	,
cord-024061-gxv8y146	60	42	42	42	CD
cord-024061-gxv8y146	60	43	)	)	-RRB-
cord-024061-gxv8y146	60	44	.	.	.
cord-024061-gxv8y146	61	1	Secondary	secondary	JJ
cord-024061-gxv8y146	61	2	Frontiers	Frontiers	NNPS
cord-024061-gxv8y146	61	3	in	in	IN
cord-024061-gxv8y146	61	4	Veterinary	Veterinary	NNP
cord-024061-gxv8y146	61	5	Science	Science	NNP
cord-024061-gxv8y146	61	6	|	|	:
cord-024061-gxv8y146	61	7	www.frontiersin.org	www.frontiersin.org	NN
cord-024061-gxv8y146	61	8	sequence	sequence	NN
cord-024061-gxv8y146	61	9	analysis	analysis	NN
cord-024061-gxv8y146	61	10	can	can	MD
cord-024061-gxv8y146	61	11	either	either	CC
cord-024061-gxv8y146	61	12	target	target	VB
cord-024061-gxv8y146	61	13	all	all	DT
cord-024061-gxv8y146	61	14	available	available	JJ
cord-024061-gxv8y146	61	15	viral	viral	JJ
cord-024061-gxv8y146	61	16	isolates	isolate	NNS
cord-024061-gxv8y146	61	17	or	or	CC
cord-024061-gxv8y146	61	18	specific	specific	JJ
cord-024061-gxv8y146	61	19	well	well	RB
cord-024061-gxv8y146	61	20	-	-	HYPH
cord-024061-gxv8y146	61	21	defined	define	VBN
cord-024061-gxv8y146	61	22	lineages	lineage	NNS
cord-024061-gxv8y146	61	23	(	(	-LRB-
cord-024061-gxv8y146	61	24	i.e.	i.e.	FW
cord-024061-gxv8y146	61	25	,	,	,
cord-024061-gxv8y146	61	26	monophyletic	monophyletic	JJ
cord-024061-gxv8y146	61	27	clades	clade	NNS
cord-024061-gxv8y146	61	28	)	)	-RRB-
cord-024061-gxv8y146	61	29	(	(	-LRB-
cord-024061-gxv8y146	61	30	38	38	CD
cord-024061-gxv8y146	61	31	,	,	,
cord-024061-gxv8y146	61	32	41	41	CD
cord-024061-gxv8y146	61	33	,	,	,
cord-024061-gxv8y146	61	34	42	42	CD
cord-024061-gxv8y146	61	35	)	)	-RRB-
cord-024061-gxv8y146	61	36	.	.	.
cord-024061-gxv8y146	62	1	To	to	TO
cord-024061-gxv8y146	62	2	reduce	reduce	VB
cord-024061-gxv8y146	62	3	the	the	DT
cord-024061-gxv8y146	62	4	impact	impact	NN
cord-024061-gxv8y146	62	5	of	of	IN
cord-024061-gxv8y146	62	6	sampling	sampling	NN
cord-024061-gxv8y146	62	7	bias	bias	NN
cord-024061-gxv8y146	62	8	on	on	IN
cord-024061-gxv8y146	62	9	the	the	DT
cord-024061-gxv8y146	62	10	results	result	NNS
cord-024061-gxv8y146	62	11	of	of	IN
cord-024061-gxv8y146	62	12	a	a	DT
cord-024061-gxv8y146	62	13	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	62	14	analyses	analysis	NNS
cord-024061-gxv8y146	62	15	,	,	,
cord-024061-gxv8y146	62	16	it	-PRON-	PRP
cord-024061-gxv8y146	62	17	is	be	VBZ
cord-024061-gxv8y146	62	18	essential	essential	JJ
cord-024061-gxv8y146	62	19	to	to	TO
cord-024061-gxv8y146	62	20	ensure	ensure	VB
cord-024061-gxv8y146	62	21	the	the	DT
cord-024061-gxv8y146	62	22	representativeness	representativeness	NN
cord-024061-gxv8y146	62	23	of	of	IN
cord-024061-gxv8y146	62	24	the	the	DT
cord-024061-gxv8y146	62	25	viral	viral	JJ
cord-024061-gxv8y146	62	26	isolates	isolate	NNS
cord-024061-gxv8y146	62	27	under	under	IN
cord-024061-gxv8y146	62	28	study	study	NN
cord-024061-gxv8y146	62	29	to	to	IN
cord-024061-gxv8y146	62	30	the	the	DT
cord-024061-gxv8y146	62	31	available	available	JJ
cord-024061-gxv8y146	62	32	sequences	sequence	NNS
cord-024061-gxv8y146	62	33	data	datum	NNS
cord-024061-gxv8y146	62	34	on	on	IN
cord-024061-gxv8y146	62	35	both	both	CC
cord-024061-gxv8y146	62	36	temporal	temporal	JJ
cord-024061-gxv8y146	62	37	and	and	CC
cord-024061-gxv8y146	62	38	spatial	spatial	JJ
cord-024061-gxv8y146	62	39	scales	scale	NNS
cord-024061-gxv8y146	62	40	.	.	.
cord-024061-gxv8y146	63	1	This	this	DT
cord-024061-gxv8y146	63	2	step	step	NN
cord-024061-gxv8y146	63	3	is	be	VBZ
cord-024061-gxv8y146	63	4	most	most	RBS
cord-024061-gxv8y146	63	5	important	important	JJ
cord-024061-gxv8y146	63	6	for	for	IN
cord-024061-gxv8y146	63	7	primary	primary	JJ
cord-024061-gxv8y146	63	8	sequence	sequence	NN
cord-024061-gxv8y146	63	9	analyses	analysis	NNS
cord-024061-gxv8y146	63	10	,	,	,
cord-024061-gxv8y146	63	11	in	in	IN
cord-024061-gxv8y146	63	12	which	which	WDT
cord-024061-gxv8y146	63	13	the	the	DT
cord-024061-gxv8y146	63	14	dataset	dataset	NN
cord-024061-gxv8y146	63	15	under	under	IN
cord-024061-gxv8y146	63	16	study	study	NN
cord-024061-gxv8y146	63	17	needs	need	VBZ
cord-024061-gxv8y146	63	18	to	to	TO
cord-024061-gxv8y146	63	19	cover	cover	VB
cord-024061-gxv8y146	63	20	all	all	DT
cord-024061-gxv8y146	63	21	close	close	JJ
cord-024061-gxv8y146	63	22	relatives	relative	NNS
cord-024061-gxv8y146	63	23	of	of	IN
cord-024061-gxv8y146	63	24	novel	novel	JJ
cord-024061-gxv8y146	63	25	viral	viral	JJ
cord-024061-gxv8y146	63	26	isolates	isolate	NNS
cord-024061-gxv8y146	63	27	published	publish	VBN
cord-024061-gxv8y146	63	28	elsewhere	elsewhere	RB
cord-024061-gxv8y146	63	29	.	.	.
cord-024061-gxv8y146	64	1	Retrieving	retrieve	VBG
cord-024061-gxv8y146	64	2	and	and	CC
cord-024061-gxv8y146	64	3	combining	combine	VBG
cord-024061-gxv8y146	64	4	relatives	relative	NNS
cord-024061-gxv8y146	64	5	of	of	IN
cord-024061-gxv8y146	64	6	novel	novel	JJ
cord-024061-gxv8y146	64	7	viral	viral	JJ
cord-024061-gxv8y146	64	8	isolates	isolate	NNS
cord-024061-gxv8y146	64	9	in	in	IN
cord-024061-gxv8y146	64	10	a	a	DT
cord-024061-gxv8y146	64	11	single	single	JJ
cord-024061-gxv8y146	64	12	dataset	dataset	NN
cord-024061-gxv8y146	64	13	will	will	MD
cord-024061-gxv8y146	64	14	warrant	warrant	VB
cord-024061-gxv8y146	64	15	a	a	DT
cord-024061-gxv8y146	64	16	proper	proper	JJ
cord-024061-gxv8y146	64	17	inference	inference	NN
cord-024061-gxv8y146	64	18	of	of	IN
cord-024061-gxv8y146	64	19	representative	representative	JJ
cord-024061-gxv8y146	64	20	phylogenetic	phylogenetic	JJ
cord-024061-gxv8y146	64	21	relationships	relationship	NNS
cord-024061-gxv8y146	64	22	of	of	IN
cord-024061-gxv8y146	64	23	a	a	DT
cord-024061-gxv8y146	64	24	tree	tree	NN
cord-024061-gxv8y146	64	25	topology	topology	NN
cord-024061-gxv8y146	64	26	based	base	VBN
cord-024061-gxv8y146	64	27	on	on	IN
cord-024061-gxv8y146	64	28	all	all	DT
cord-024061-gxv8y146	64	29	available	available	JJ
cord-024061-gxv8y146	64	30	related	related	JJ
cord-024061-gxv8y146	64	31	sequences	sequence	NNS
cord-024061-gxv8y146	64	32	.	.	.
cord-024061-gxv8y146	65	1	As	as	IN
cord-024061-gxv8y146	65	2	on	on	IN
cord-024061-gxv8y146	65	3	many	many	JJ
cord-024061-gxv8y146	65	4	occasions	occasion	NNS
cord-024061-gxv8y146	65	5	,	,	,
cord-024061-gxv8y146	65	6	novel	novel	NN
cord-024061-gxv8y146	65	7	sequences	sequence	NNS
cord-024061-gxv8y146	65	8	might	may	MD
cord-024061-gxv8y146	65	9	belong	belong	VB
cord-024061-gxv8y146	65	10	to	to	IN
cord-024061-gxv8y146	65	11	different	different	JJ
cord-024061-gxv8y146	65	12	distinct	distinct	JJ
cord-024061-gxv8y146	65	13	viral	viral	JJ
cord-024061-gxv8y146	65	14	lineages	lineage	NNS
cord-024061-gxv8y146	65	15	published	publish	VBN
cord-024061-gxv8y146	65	16	elsewhere	elsewhere	RB
cord-024061-gxv8y146	65	17	(	(	-LRB-
cord-024061-gxv8y146	65	18	39	39	CD
cord-024061-gxv8y146	65	19	,	,	,
cord-024061-gxv8y146	65	20	43	43	CD
cord-024061-gxv8y146	65	21	)	)	-RRB-
cord-024061-gxv8y146	65	22	.	.	.
cord-024061-gxv8y146	66	1	The	the	DT
cord-024061-gxv8y146	66	2	basic	basic	JJ
cord-024061-gxv8y146	66	3	local	local	JJ
cord-024061-gxv8y146	66	4	alignment	alignment	NN
cord-024061-gxv8y146	66	5	search	search	NN
cord-024061-gxv8y146	66	6	tool	tool	NN
cord-024061-gxv8y146	66	7	(	(	-LRB-
cord-024061-gxv8y146	66	8	BLAST	blast	NN
cord-024061-gxv8y146	66	9	;	;	:
cord-024061-gxv8y146	66	10	https://blast.ncbi.nlm.nih.gov/Blast.cgi	https://blast.ncbi.nlm.nih.gov/Blast.cgi	NNP
cord-024061-gxv8y146	66	11	)	)	-RRB-
cord-024061-gxv8y146	66	12	is	be	VBZ
cord-024061-gxv8y146	66	13	the	the	DT
cord-024061-gxv8y146	66	14	most	most	RBS
cord-024061-gxv8y146	66	15	popular	popular	JJ
cord-024061-gxv8y146	66	16	tool	tool	NN
cord-024061-gxv8y146	66	17	for	for	IN
cord-024061-gxv8y146	66	18	retrieving	retrieve	VBG
cord-024061-gxv8y146	66	19	relatives	relative	NNS
cord-024061-gxv8y146	66	20	of	of	IN
cord-024061-gxv8y146	66	21	novel	novel	NN
cord-024061-gxv8y146	66	22	sequences	sequence	NNS
cord-024061-gxv8y146	66	23	(	(	-LRB-
cord-024061-gxv8y146	66	24	Figure	figure	NN
cord-024061-gxv8y146	66	25	1	1	CD
cord-024061-gxv8y146	66	26	)	)	-RRB-
cord-024061-gxv8y146	66	27	.	.	.
cord-024061-gxv8y146	67	1	Finally	finally	RB
cord-024061-gxv8y146	67	2	,	,	,
cord-024061-gxv8y146	67	3	the	the	DT
cord-024061-gxv8y146	67	4	retrieval	retrieval	NN
cord-024061-gxv8y146	67	5	process	process	NN
cord-024061-gxv8y146	67	6	should	should	MD
cord-024061-gxv8y146	67	7	include	include	VB
cord-024061-gxv8y146	67	8	complete	complete	JJ
cord-024061-gxv8y146	67	9	and	and	CC
cord-024061-gxv8y146	67	10	near	near	RB
cord-024061-gxv8y146	67	11	-	-	HYPH
cord-024061-gxv8y146	67	12	complete	complete	JJ
cord-024061-gxv8y146	67	13	sequences	sequence	NNS
cord-024061-gxv8y146	67	14	to	to	TO
cord-024061-gxv8y146	67	15	avoid	avoid	VB
cord-024061-gxv8y146	67	16	distorting	distort	VBG
cord-024061-gxv8y146	67	17	the	the	DT
cord-024061-gxv8y146	67	18	phylogenetic	phylogenetic	JJ
cord-024061-gxv8y146	67	19	relationships	relationship	NNS
cord-024061-gxv8y146	67	20	between	between	IN
cord-024061-gxv8y146	67	21	the	the	DT
cord-024061-gxv8y146	67	22	novel	novel	NN
cord-024061-gxv8y146	67	23	and	and	CC
cord-024061-gxv8y146	67	24	the	the	DT
cord-024061-gxv8y146	67	25	related	related	JJ
cord-024061-gxv8y146	67	26	isolates	isolate	NNS
cord-024061-gxv8y146	67	27	.	.	.
cord-024061-gxv8y146	68	1	The	the	DT
cord-024061-gxv8y146	68	2	integration	integration	NN
cord-024061-gxv8y146	68	3	of	of	IN
cord-024061-gxv8y146	68	4	a	a	DT
cord-024061-gxv8y146	68	5	pathogen	pathogen	NN
cord-024061-gxv8y146	68	6	's	's	POS
cord-024061-gxv8y146	68	7	epidemiological	epidemiological	JJ
cord-024061-gxv8y146	68	8	characteristics	characteristic	NNS
cord-024061-gxv8y146	68	9	into	into	IN
cord-024061-gxv8y146	68	10	its	-PRON-	PRP$
cord-024061-gxv8y146	68	11	inferred	infer	VBN
cord-024061-gxv8y146	68	12	phylogeny	phylogeny	NN
cord-024061-gxv8y146	68	13	is	be	VBZ
cord-024061-gxv8y146	68	14	the	the	DT
cord-024061-gxv8y146	68	15	ultimate	ultimate	JJ
cord-024061-gxv8y146	68	16	justification	justification	NN
cord-024061-gxv8y146	68	17	for	for	IN
cord-024061-gxv8y146	68	18	the	the	DT
cord-024061-gxv8y146	68	19	preference	preference	NN
cord-024061-gxv8y146	68	20	of	of	IN
cord-024061-gxv8y146	68	21	the	the	DT
cord-024061-gxv8y146	68	22	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	68	23	approach	approach	NN
cord-024061-gxv8y146	68	24	over	over	IN
cord-024061-gxv8y146	68	25	the	the	DT
cord-024061-gxv8y146	68	26	classical	classical	JJ
cord-024061-gxv8y146	68	27	phylogenetic	phylogenetic	JJ
cord-024061-gxv8y146	68	28	methods	method	NNS
cord-024061-gxv8y146	68	29	.	.	.
cord-024061-gxv8y146	69	1	Therefore	therefore	RB
cord-024061-gxv8y146	69	2	,	,	,
cord-024061-gxv8y146	69	3	the	the	DT
cord-024061-gxv8y146	69	4	thorough	thorough	JJ
cord-024061-gxv8y146	69	5	preparation	preparation	NN
cord-024061-gxv8y146	69	6	of	of	IN
cord-024061-gxv8y146	69	7	sequence	sequence	NN
cord-024061-gxv8y146	69	8	metadata	metadata	NN
cord-024061-gxv8y146	69	9	,	,	,
cord-024061-gxv8y146	69	10	which	which	WDT
cord-024061-gxv8y146	69	11	includes	include	VBZ
cord-024061-gxv8y146	69	12	retrieval	retrieval	NN
cord-024061-gxv8y146	69	13	of	of	IN
cord-024061-gxv8y146	69	14	information	information	NN
cord-024061-gxv8y146	69	15	related	relate	VBN
cord-024061-gxv8y146	69	16	to	to	IN
cord-024061-gxv8y146	69	17	the	the	DT
cord-024061-gxv8y146	69	18	isolate	isolate	NN
cord-024061-gxv8y146	69	19	under	under	IN
cord-024061-gxv8y146	69	20	study	study	NN
cord-024061-gxv8y146	69	21	,	,	,
cord-024061-gxv8y146	69	22	is	be	VBZ
cord-024061-gxv8y146	69	23	another	another	DT
cord-024061-gxv8y146	69	24	critical	critical	JJ
cord-024061-gxv8y146	69	25	step	step	NN
cord-024061-gxv8y146	69	26	for	for	IN
cord-024061-gxv8y146	69	27	a	a	DT
cord-024061-gxv8y146	69	28	sound	sound	JJ
cord-024061-gxv8y146	69	29	subsequent	subsequent	JJ
cord-024061-gxv8y146	69	30	phylodynamic	phylodynamic	NN
cord-024061-gxv8y146	69	31	analysis	analysis	NN
cord-024061-gxv8y146	69	32	.	.	.
cord-024061-gxv8y146	70	1	Sequence	sequence	NN
cord-024061-gxv8y146	70	2	metadata	metadata	NN
cord-024061-gxv8y146	70	3	can	can	MD
cord-024061-gxv8y146	70	4	be	be	VB
cord-024061-gxv8y146	70	5	retrieved	retrieve	VBN
cord-024061-gxv8y146	70	6	either	either	CC
cord-024061-gxv8y146	70	7	from	from	IN
cord-024061-gxv8y146	70	8	public	public	JJ
cord-024061-gxv8y146	70	9	genomic	genomic	JJ
cord-024061-gxv8y146	70	10	databases	database	NNS
cord-024061-gxv8y146	70	11	such	such	JJ
cord-024061-gxv8y146	70	12	as	as	IN
cord-024061-gxv8y146	70	13	the	the	DT
cord-024061-gxv8y146	70	14	Genbank	Genbank	NNP
cord-024061-gxv8y146	70	15	or	or	CC
cord-024061-gxv8y146	70	16	from	from	IN
cord-024061-gxv8y146	70	17	the	the	DT
cord-024061-gxv8y146	70	18	related	related	JJ
cord-024061-gxv8y146	70	19	published	publish	VBN
cord-024061-gxv8y146	70	20	literature	literature	NN
cord-024061-gxv8y146	70	21	.	.	.
cord-024061-gxv8y146	71	1	Because	because	IN
cord-024061-gxv8y146	71	2	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	71	3	methods	method	NNS
cord-024061-gxv8y146	71	4	largely	largely	RB
cord-024061-gxv8y146	71	5	depend	depend	VBP
cord-024061-gxv8y146	71	6	on	on	IN
cord-024061-gxv8y146	71	7	time	time	NN
cord-024061-gxv8y146	71	8	-	-	HYPH
cord-024061-gxv8y146	71	9	stamped	stamp	VBN
cord-024061-gxv8y146	71	10	data	datum	NNS
cord-024061-gxv8y146	71	11	,	,	,
cord-024061-gxv8y146	71	12	this	this	DT
cord-024061-gxv8y146	71	13	step	step	NN
cord-024061-gxv8y146	71	14	starts	start	VBZ
cord-024061-gxv8y146	71	15	with	with	IN
cord-024061-gxv8y146	71	16	retrieving	retrieve	VBG
cord-024061-gxv8y146	71	17	the	the	DT
cord-024061-gxv8y146	71	18	data	datum	NNS
cord-024061-gxv8y146	71	19	of	of	IN
cord-024061-gxv8y146	71	20	collection	collection	NN
cord-024061-gxv8y146	71	21	for	for	IN
cord-024061-gxv8y146	71	22	the	the	DT
cord-024061-gxv8y146	71	23	viral	viral	JJ
cord-024061-gxv8y146	71	24	isolates	isolate	NNS
cord-024061-gxv8y146	71	25	under	under	IN
cord-024061-gxv8y146	71	26	study	study	NN
cord-024061-gxv8y146	71	27	.	.	.
cord-024061-gxv8y146	72	1	Thus	thus	RB
cord-024061-gxv8y146	72	2	,	,	,
cord-024061-gxv8y146	72	3	viral	viral	JJ
cord-024061-gxv8y146	72	4	isolates	isolate	NNS
cord-024061-gxv8y146	72	5	with	with	IN
cord-024061-gxv8y146	72	6	no	no	DT
cord-024061-gxv8y146	72	7	temporal	temporal	JJ
cord-024061-gxv8y146	72	8	data	datum	NNS
cord-024061-gxv8y146	72	9	are	be	VBP
cord-024061-gxv8y146	72	10	typically	typically	RB
cord-024061-gxv8y146	72	11	excluded	exclude	VBN
cord-024061-gxv8y146	72	12	from	from	IN
cord-024061-gxv8y146	72	13	the	the	DT
cord-024061-gxv8y146	72	14	analyses	analysis	NNS
cord-024061-gxv8y146	72	15	pipeline	pipeline	NN
cord-024061-gxv8y146	72	16	.	.	.
cord-024061-gxv8y146	73	1	Next	next	RB
cord-024061-gxv8y146	73	2	,	,	,
cord-024061-gxv8y146	73	3	the	the	DT
cord-024061-gxv8y146	73	4	date	date	NN
cord-024061-gxv8y146	73	5	of	of	IN
cord-024061-gxv8y146	73	6	collection	collection	NN
cord-024061-gxv8y146	73	7	is	be	VBZ
cord-024061-gxv8y146	73	8	converted	convert	VBN
cord-024061-gxv8y146	73	9	into	into	IN
cord-024061-gxv8y146	73	10	BEAST	beast	NN
cord-024061-gxv8y146	73	11	readable	readable	JJ
cord-024061-gxv8y146	73	12	format	format	NN
cord-024061-gxv8y146	73	13	known	know	VBN
cord-024061-gxv8y146	73	14	as	as	IN
cord-024061-gxv8y146	73	15	fractional	fractional	JJ
cord-024061-gxv8y146	73	16	years	year	NNS
cord-024061-gxv8y146	73	17	to	to	TO
cord-024061-gxv8y146	73	18	estimate	estimate	VB
cord-024061-gxv8y146	73	19	divergence	divergence	NN
cord-024061-gxv8y146	73	20	times	time	NNS
cord-024061-gxv8y146	73	21	.	.	.
cord-024061-gxv8y146	74	1	For	for	IN
cord-024061-gxv8y146	74	2	example	example	NN
cord-024061-gxv8y146	74	3	,	,	,
cord-024061-gxv8y146	74	4	a	a	DT
cord-024061-gxv8y146	74	5	virus	virus	NN
cord-024061-gxv8y146	74	6	collected	collect	VBN
cord-024061-gxv8y146	74	7	on	on	IN
cord-024061-gxv8y146	74	8	April	April	NNP
cord-024061-gxv8y146	74	9	14	14	CD
cord-024061-gxv8y146	74	10	,	,	,
cord-024061-gxv8y146	74	11	2017	2017	CD
cord-024061-gxv8y146	74	12	,	,	,
cord-024061-gxv8y146	74	13	is	be	VBZ
cord-024061-gxv8y146	74	14	converted	convert	VBN
cord-024061-gxv8y146	74	15	into	into	IN
cord-024061-gxv8y146	74	16	"	"	``
cord-024061-gxv8y146	74	17	2017.282	2017.282	NNS
cord-024061-gxv8y146	74	18	"	"	''
cord-024061-gxv8y146	74	19	as	as	IN
cord-024061-gxv8y146	74	20	a	a	DT
cord-024061-gxv8y146	74	21	fractional	fractional	JJ
cord-024061-gxv8y146	74	22	year	year	NN
cord-024061-gxv8y146	74	23	,	,	,
cord-024061-gxv8y146	74	24	where	where	WRB
cord-024061-gxv8y146	74	25	"	"	``
cord-024061-gxv8y146	74	26	2017	2017	CD
cord-024061-gxv8y146	74	27	"	"	''
cord-024061-gxv8y146	74	28	is	be	VBZ
cord-024061-gxv8y146	74	29	the	the	DT
cord-024061-gxv8y146	74	30	year	year	NN
cord-024061-gxv8y146	74	31	of	of	IN
cord-024061-gxv8y146	74	32	collection	collection	NN
cord-024061-gxv8y146	74	33	,	,	,
cord-024061-gxv8y146	74	34	and	and	CC
cord-024061-gxv8y146	74	35	"	"	``
cord-024061-gxv8y146	74	36	0.282	0.282	CD
cord-024061-gxv8y146	74	37	"	"	''
cord-024061-gxv8y146	74	38	is	be	VBZ
cord-024061-gxv8y146	74	39	the	the	DT
cord-024061-gxv8y146	74	40	number	number	NN
cord-024061-gxv8y146	74	41	of	of	IN
cord-024061-gxv8y146	74	42	days	day	NNS
cord-024061-gxv8y146	74	43	from	from	IN
cord-024061-gxv8y146	74	44	the	the	DT
cord-024061-gxv8y146	74	45	beginning	beginning	NN
cord-024061-gxv8y146	74	46	of	of	IN
cord-024061-gxv8y146	74	47	that	that	DT
cord-024061-gxv8y146	74	48	year	year	NN
cord-024061-gxv8y146	74	49	till	till	IN
cord-024061-gxv8y146	74	50	the	the	DT
cord-024061-gxv8y146	74	51	day	day	NN
cord-024061-gxv8y146	74	52	for	for	IN
cord-024061-gxv8y146	74	53	sequence	sequence	NN
cord-024061-gxv8y146	74	54	collection	collection	NN
cord-024061-gxv8y146	74	55	divided	divide	VBN
cord-024061-gxv8y146	74	56	by	by	IN
cord-024061-gxv8y146	74	57	the	the	DT
cord-024061-gxv8y146	74	58	total	total	JJ
cord-024061-gxv8y146	74	59	number	number	NN
cord-024061-gxv8y146	74	60	of	of	IN
cord-024061-gxv8y146	74	61	days	day	NNS
cord-024061-gxv8y146	74	62	within	within	IN
cord-024061-gxv8y146	74	63	a	a	DT
cord-024061-gxv8y146	74	64	typical	typical	JJ
cord-024061-gxv8y146	74	65	year	year	NN
cord-024061-gxv8y146	74	66	.	.	.
cord-024061-gxv8y146	75	1	Additionally	additionally	RB
cord-024061-gxv8y146	75	2	,	,	,
cord-024061-gxv8y146	75	3	dates	date	NNS
cord-024061-gxv8y146	75	4	can	can	MD
cord-024061-gxv8y146	75	5	be	be	VB
cord-024061-gxv8y146	75	6	imported	import	VBN
cord-024061-gxv8y146	75	7	to	to	IN
cord-024061-gxv8y146	75	8	BEAUTi	BEAUTi	NNS
cord-024061-gxv8y146	75	9	by	by	IN
cord-024061-gxv8y146	75	10	a	a	DT
cord-024061-gxv8y146	75	11	separate	separate	JJ
cord-024061-gxv8y146	75	12	text	text	NN
cord-024061-gxv8y146	75	13	file	file	NN
cord-024061-gxv8y146	75	14	that	that	WDT
cord-024061-gxv8y146	75	15	include	include	VBP
cord-024061-gxv8y146	75	16	the	the	DT
cord-024061-gxv8y146	75	17	complete	complete	JJ
cord-024061-gxv8y146	75	18	date	date	NN
cord-024061-gxv8y146	75	19	of	of	IN
cord-024061-gxv8y146	75	20	sequence	sequence	NN
cord-024061-gxv8y146	75	21	collection	collection	NN
cord-024061-gxv8y146	75	22	with	with	IN
cord-024061-gxv8y146	75	23	explicit	explicit	JJ
cord-024061-gxv8y146	75	24	separators	separator	NNS
cord-024061-gxv8y146	75	25	(	(	-LRB-
cord-024061-gxv8y146	75	26	e.g.	e.g.	RB
cord-024061-gxv8y146	75	27	,	,	,
cord-024061-gxv8y146	75	28	-or	-or	NN
cord-024061-gxv8y146	75	29	/	/	SYM
cord-024061-gxv8y146	75	30	)	)	-RRB-
cord-024061-gxv8y146	75	31	.	.	.
cord-024061-gxv8y146	76	1	However	however	RB
cord-024061-gxv8y146	76	2	,	,	,
cord-024061-gxv8y146	76	3	in	in	IN
cord-024061-gxv8y146	76	4	many	many	JJ
cord-024061-gxv8y146	76	5	instances	instance	NNS
cord-024061-gxv8y146	76	6	,	,	,
cord-024061-gxv8y146	76	7	the	the	DT
cord-024061-gxv8y146	76	8	complete	complete	JJ
cord-024061-gxv8y146	76	9	date	date	NN
cord-024061-gxv8y146	76	10	of	of	IN
cord-024061-gxv8y146	76	11	collection	collection	NN
cord-024061-gxv8y146	76	12	is	be	VBZ
cord-024061-gxv8y146	76	13	not	not	RB
cord-024061-gxv8y146	76	14	available	available	JJ
cord-024061-gxv8y146	76	15	,	,	,
cord-024061-gxv8y146	76	16	in	in	IN
cord-024061-gxv8y146	76	17	which	which	WDT
cord-024061-gxv8y146	76	18	it	-PRON-	PRP
cord-024061-gxv8y146	76	19	misses	miss	VBZ
cord-024061-gxv8y146	76	20	either	either	CC
cord-024061-gxv8y146	76	21	the	the	DT
cord-024061-gxv8y146	76	22	exact	exact	JJ
cord-024061-gxv8y146	76	23	date	date	NN
cord-024061-gxv8y146	76	24	or	or	CC
cord-024061-gxv8y146	76	25	month	month	NN
cord-024061-gxv8y146	76	26	of	of	IN
cord-024061-gxv8y146	76	27	collection	collection	NN
cord-024061-gxv8y146	76	28	.	.	.
cord-024061-gxv8y146	77	1	Therefore	therefore	RB
cord-024061-gxv8y146	77	2	,	,	,
cord-024061-gxv8y146	77	3	we	-PRON-	PRP
cord-024061-gxv8y146	77	4	can	can	MD
cord-024061-gxv8y146	77	5	either	either	CC
cord-024061-gxv8y146	77	6	specify	specify	VB
cord-024061-gxv8y146	77	7	the	the	DT
cord-024061-gxv8y146	77	8	age	age	NN
cord-024061-gxv8y146	77	9	of	of	IN
cord-024061-gxv8y146	77	10	the	the	DT
cord-024061-gxv8y146	77	11	isolate	isolate	NN
cord-024061-gxv8y146	77	12	as	as	IN
cord-024061-gxv8y146	77	13	the	the	DT
cord-024061-gxv8y146	77	14	mid	mid	NN
cord-024061-gxv8y146	77	15	-	-	NN
cord-024061-gxv8y146	77	16	point	point	NN
cord-024061-gxv8y146	77	17	of	of	IN
cord-024061-gxv8y146	77	18	the	the	DT
cord-024061-gxv8y146	77	19	corresponding	corresponding	JJ
cord-024061-gxv8y146	77	20	month	month	NN
cord-024061-gxv8y146	77	21	or	or	CC
cord-024061-gxv8y146	77	22	year	year	NN
cord-024061-gxv8y146	77	23	,	,	,
cord-024061-gxv8y146	77	24	respectively	respectively	RB
cord-024061-gxv8y146	77	25	.	.	.
cord-024061-gxv8y146	78	1	Other	other	JJ
cord-024061-gxv8y146	78	2	epidemiological	epidemiological	JJ
cord-024061-gxv8y146	78	3	characteristics	characteristic	NNS
cord-024061-gxv8y146	79	1	such	such	JJ
cord-024061-gxv8y146	79	2	spatial	spatial	JJ
cord-024061-gxv8y146	79	3	or	or	CC
cord-024061-gxv8y146	79	4	host	host	NN
cord-024061-gxv8y146	79	5	information	information	NN
cord-024061-gxv8y146	79	6	can	can	MD
cord-024061-gxv8y146	79	7	be	be	VB
cord-024061-gxv8y146	79	8	prepared	prepare	VBN
cord-024061-gxv8y146	79	9	in	in	IN
cord-024061-gxv8y146	79	10	a	a	DT
cord-024061-gxv8y146	79	11	separate	separate	JJ
cord-024061-gxv8y146	79	12	text	text	NN
cord-024061-gxv8y146	79	13	delaminated	delaminate	VBN
cord-024061-gxv8y146	79	14	format	format	NN
cord-024061-gxv8y146	79	15	with	with	IN
cord-024061-gxv8y146	79	16	unique	unique	JJ
cord-024061-gxv8y146	79	17	identifiers	identifier	NNS
cord-024061-gxv8y146	79	18	that	that	WDT
cord-024061-gxv8y146	79	19	link	link	VBP
cord-024061-gxv8y146	79	20	them	-PRON-	PRP
cord-024061-gxv8y146	79	21	to	to	IN
cord-024061-gxv8y146	79	22	the	the	DT
cord-024061-gxv8y146	79	23	isolates	isolate	NNS
cord-024061-gxv8y146	79	24	in	in	IN
cord-024061-gxv8y146	79	25	the	the	DT
cord-024061-gxv8y146	79	26	sequence	sequence	NN
cord-024061-gxv8y146	79	27	dataset	dataset	NN
cord-024061-gxv8y146	79	28	.	.	.
cord-024061-gxv8y146	80	1	Isolates	isolate	NNS
cord-024061-gxv8y146	80	2	missing	miss	VBG
cord-024061-gxv8y146	80	3	a	a	DT
cord-024061-gxv8y146	80	4	none	none	NN
cord-024061-gxv8y146	80	5	-	-	HYPH
cord-024061-gxv8y146	80	6	temporal	temporal	JJ
cord-024061-gxv8y146	80	7	information	information	NN
cord-024061-gxv8y146	80	8	should	should	MD
cord-024061-gxv8y146	80	9	be	be	VB
cord-024061-gxv8y146	80	10	kept	keep	VBN
cord-024061-gxv8y146	80	11	in	in	IN
cord-024061-gxv8y146	80	12	the	the	DT
cord-024061-gxv8y146	80	13	analyses	analysis	NNS
cord-024061-gxv8y146	80	14	and	and	CC
cord-024061-gxv8y146	80	15	are	be	VBP
cord-024061-gxv8y146	80	16	usually	usually	RB
cord-024061-gxv8y146	80	17	labeled	label	VBN
cord-024061-gxv8y146	80	18	with	with	IN
cord-024061-gxv8y146	80	19	a	a	DT
cord-024061-gxv8y146	80	20	question	question	NN
cord-024061-gxv8y146	80	21	mark	mark	NN
cord-024061-gxv8y146	80	22	"	"	''
cord-024061-gxv8y146	80	23	?	?	.
cord-024061-gxv8y146	80	24	"	"	''
cord-024061-gxv8y146	80	25	to	to	TO
cord-024061-gxv8y146	80	26	represent	represent	VB
cord-024061-gxv8y146	80	27	a	a	DT
cord-024061-gxv8y146	80	28	missing	miss	VBG
cord-024061-gxv8y146	80	29	information	information	NN
cord-024061-gxv8y146	80	30	.	.	.
cord-024061-gxv8y146	81	1	In	in	IN
cord-024061-gxv8y146	81	2	the	the	DT
cord-024061-gxv8y146	81	3	context	context	NN
cord-024061-gxv8y146	81	4	of	of	IN
cord-024061-gxv8y146	81	5	the	the	DT
cord-024061-gxv8y146	81	6	phylodynamic	phylodynamic	NNP
cord-024061-gxv8y146	81	7	field	field	NN
cord-024061-gxv8y146	81	8	,	,	,
cord-024061-gxv8y146	81	9	epidemiological	epidemiological	JJ
cord-024061-gxv8y146	81	10	characteristics	characteristic	NNS
cord-024061-gxv8y146	81	11	such	such	JJ
cord-024061-gxv8y146	81	12	as	as	IN
cord-024061-gxv8y146	81	13	country	country	NN
cord-024061-gxv8y146	81	14	or	or	CC
cord-024061-gxv8y146	81	15	host	host	NN
cord-024061-gxv8y146	81	16	of	of	IN
cord-024061-gxv8y146	81	17	origin	origin	NN
cord-024061-gxv8y146	81	18	are	be	VBP
cord-024061-gxv8y146	81	19	defined	define	VBN
cord-024061-gxv8y146	81	20	as	as	IN
cord-024061-gxv8y146	81	21	a	a	DT
cord-024061-gxv8y146	81	22	discrete	discrete	JJ
cord-024061-gxv8y146	81	23	trait	trait	NN
cord-024061-gxv8y146	81	24	and	and	CC
cord-024061-gxv8y146	81	25	are	be	VBP
cord-024061-gxv8y146	81	26	described	describe	VBN
cord-024061-gxv8y146	81	27	in	in	IN
cord-024061-gxv8y146	81	28	more	more	JJR
cord-024061-gxv8y146	81	29	detail	detail	NN
cord-024061-gxv8y146	81	30	in	in	IN
cord-024061-gxv8y146	81	31	the	the	DT
cord-024061-gxv8y146	81	32	Running	running	NN
cord-024061-gxv8y146	81	33	and	and	CC
cord-024061-gxv8y146	81	34	Selecting	select	VBG
cord-024061-gxv8y146	81	35	Phylodynamic	Phylodynamic	NNP
cord-024061-gxv8y146	81	36	Models	Models	NNPS
cord-024061-gxv8y146	81	37	section	section	NN
cord-024061-gxv8y146	81	38	.	.	.
cord-024061-gxv8y146	82	1	However	however	RB
cord-024061-gxv8y146	82	2	,	,	,
cord-024061-gxv8y146	82	3	careful	careful	JJ
cord-024061-gxv8y146	82	4	selection	selection	NN
cord-024061-gxv8y146	82	5	of	of	IN
cord-024061-gxv8y146	82	6	these	these	DT
cord-024061-gxv8y146	82	7	characteristics	characteristic	NNS
cord-024061-gxv8y146	82	8	is	be	VBZ
cord-024061-gxv8y146	82	9	recommended	recommend	VBN
cord-024061-gxv8y146	82	10	to	to	TO
cord-024061-gxv8y146	82	11	be	be	VB
cord-024061-gxv8y146	82	12	considered	consider	VBN
cord-024061-gxv8y146	82	13	at	at	IN
cord-024061-gxv8y146	82	14	the	the	DT
cord-024061-gxv8y146	82	15	beginning	beginning	NN
cord-024061-gxv8y146	82	16	of	of	IN
cord-024061-gxv8y146	82	17	the	the	DT
cord-024061-gxv8y146	82	18	analyses	analysis	NNS
cord-024061-gxv8y146	82	19	pipeline	pipeline	NN
cord-024061-gxv8y146	82	20	as	as	IN
cord-024061-gxv8y146	82	21	a	a	DT
cord-024061-gxv8y146	82	22	critical	critical	JJ
cord-024061-gxv8y146	82	23	part	part	NN
cord-024061-gxv8y146	82	24	of	of	IN
cord-024061-gxv8y146	82	25	the	the	DT
cord-024061-gxv8y146	82	26	data	data	NN
cord-024061-gxv8y146	82	27	preparation	preparation	NN
cord-024061-gxv8y146	82	28	for	for	IN
cord-024061-gxv8y146	82	29	the	the	DT
cord-024061-gxv8y146	82	30	subsequent	subsequent	JJ
cord-024061-gxv8y146	82	31	analyses	analysis	NNS
cord-024061-gxv8y146	82	32	.	.	.
cord-024061-gxv8y146	83	1	Geographical	geographical	JJ
cord-024061-gxv8y146	83	2	discrete	discrete	JJ
cord-024061-gxv8y146	83	3	traits	trait	NNS
cord-024061-gxv8y146	83	4	can	can	MD
cord-024061-gxv8y146	83	5	be	be	VB
cord-024061-gxv8y146	83	6	defined	define	VBN
cord-024061-gxv8y146	83	7	as	as	IN
cord-024061-gxv8y146	83	8	the	the	DT
cord-024061-gxv8y146	83	9	country	country	NN
cord-024061-gxv8y146	83	10	of	of	IN
cord-024061-gxv8y146	83	11	origin	origin	NN
cord-024061-gxv8y146	83	12	where	where	WRB
cord-024061-gxv8y146	83	13	the	the	DT
cord-024061-gxv8y146	83	14	pathogen	pathogen	NN
cord-024061-gxv8y146	83	15	was	be	VBD
cord-024061-gxv8y146	83	16	isolated	isolate	VBN
cord-024061-gxv8y146	83	17	or	or	CC
cord-024061-gxv8y146	83	18	can	can	MD
cord-024061-gxv8y146	83	19	be	be	VB
cord-024061-gxv8y146	83	20	redefined	redefine	VBN
cord-024061-gxv8y146	83	21	on	on	IN
cord-024061-gxv8y146	83	22	smaller	small	JJR
cord-024061-gxv8y146	83	23	or	or	CC
cord-024061-gxv8y146	83	24	larger	large	JJR
cord-024061-gxv8y146	83	25	spatial	spatial	JJ
cord-024061-gxv8y146	83	26	scales	scale	NNS
cord-024061-gxv8y146	83	27	such	such	JJ
cord-024061-gxv8y146	83	28	as	as	IN
cord-024061-gxv8y146	83	29	administrative	administrative	JJ
cord-024061-gxv8y146	83	30	regions	region	NNS
cord-024061-gxv8y146	83	31	within	within	IN
cord-024061-gxv8y146	83	32	a	a	DT
cord-024061-gxv8y146	83	33	country	country	NN
cord-024061-gxv8y146	83	34	(	(	-LRB-
cord-024061-gxv8y146	83	35	44	44	CD
cord-024061-gxv8y146	83	36	)	)	-RRB-
cord-024061-gxv8y146	83	37	or	or	CC
cord-024061-gxv8y146	83	38	continental	continental	JJ
cord-024061-gxv8y146	83	39	scale	scale	NN
cord-024061-gxv8y146	83	40	(	(	-LRB-
cord-024061-gxv8y146	83	41	32	32	CD
cord-024061-gxv8y146	83	42	)	)	-RRB-
cord-024061-gxv8y146	83	43	,	,	,
cord-024061-gxv8y146	83	44	respectively	respectively	RB
cord-024061-gxv8y146	83	45	,	,	,
cord-024061-gxv8y146	83	46	depending	depend	VBG
cord-024061-gxv8y146	83	47	on	on	IN
cord-024061-gxv8y146	83	48	the	the	DT
cord-024061-gxv8y146	83	49	study	study	NN
cord-024061-gxv8y146	83	50	's	's	POS
cord-024061-gxv8y146	83	51	hypothesis	hypothesis	NN
cord-024061-gxv8y146	83	52	.	.	.
cord-024061-gxv8y146	84	1	Besides	besides	IN
cord-024061-gxv8y146	84	2	the	the	DT
cord-024061-gxv8y146	84	3	host	host	NN
cord-024061-gxv8y146	84	4	of	of	IN
cord-024061-gxv8y146	84	5	origin	origin	NN
cord-024061-gxv8y146	84	6	,	,	,
cord-024061-gxv8y146	84	7	other	other	JJ
cord-024061-gxv8y146	84	8	non	non	JJ
cord-024061-gxv8y146	84	9	-	-	JJ
cord-024061-gxv8y146	84	10	spatial	spatial	JJ
cord-024061-gxv8y146	84	11	discrete	discrete	JJ
cord-024061-gxv8y146	84	12	traits	trait	NNS
cord-024061-gxv8y146	84	13	such	such	JJ
cord-024061-gxv8y146	84	14	as	as	IN
cord-024061-gxv8y146	84	15	host	host	NN
cord-024061-gxv8y146	84	16	and	and	CC
cord-024061-gxv8y146	84	17	environmental	environmental	JJ
cord-024061-gxv8y146	84	18	attributes	attribute	NNS
cord-024061-gxv8y146	84	19	can	can	MD
cord-024061-gxv8y146	84	20	also	also	RB
cord-024061-gxv8y146	84	21	be	be	VB
cord-024061-gxv8y146	84	22	defined	define	VBN
cord-024061-gxv8y146	84	23	as	as	IN
cord-024061-gxv8y146	84	24	discrete	discrete	JJ
cord-024061-gxv8y146	84	25	traits	trait	NNS
cord-024061-gxv8y146	84	26	(	(	-LRB-
cord-024061-gxv8y146	84	27	45	45	CD
cord-024061-gxv8y146	84	28	)	)	-RRB-
cord-024061-gxv8y146	84	29	.	.	.
cord-024061-gxv8y146	85	1	Multisequence	Multisequence	NNP
cord-024061-gxv8y146	85	2	alignment	alignment	NN
cord-024061-gxv8y146	85	3	(	(	-LRB-
cord-024061-gxv8y146	85	4	MSA	MSA	NNP
cord-024061-gxv8y146	85	5	)	)	-RRB-
cord-024061-gxv8y146	85	6	is	be	VBZ
cord-024061-gxv8y146	85	7	another	another	DT
cord-024061-gxv8y146	85	8	primary	primary	JJ
cord-024061-gxv8y146	85	9	key	key	JJ
cord-024061-gxv8y146	85	10	step	step	NN
cord-024061-gxv8y146	85	11	in	in	IN
cord-024061-gxv8y146	85	12	the	the	DT
cord-024061-gxv8y146	85	13	data	data	NN
cord-024061-gxv8y146	85	14	preparation	preparation	NN
cord-024061-gxv8y146	85	15	stage	stage	NN
cord-024061-gxv8y146	85	16	of	of	IN
cord-024061-gxv8y146	85	17	the	the	DT
cord-024061-gxv8y146	85	18	pathogen	pathogen	NN
cord-024061-gxv8y146	85	19	's	's	POS
cord-024061-gxv8y146	85	20	genetic	genetic	JJ
cord-024061-gxv8y146	85	21	data	datum	NNS
cord-024061-gxv8y146	85	22	(	(	-LRB-
cord-024061-gxv8y146	85	23	Figure	figure	NN
cord-024061-gxv8y146	85	24	1	1	CD
cord-024061-gxv8y146	85	25	)	)	-RRB-
cord-024061-gxv8y146	85	26	.	.	.
cord-024061-gxv8y146	86	1	It	-PRON-	PRP
cord-024061-gxv8y146	86	2	is	be	VBZ
cord-024061-gxv8y146	86	3	worth	worth	JJ
cord-024061-gxv8y146	86	4	noting	note	VBG
cord-024061-gxv8y146	86	5	that	that	DT
cord-024061-gxv8y146	86	6	alignment	alignment	NN
cord-024061-gxv8y146	86	7	uncertainty	uncertainty	NN
cord-024061-gxv8y146	86	8	,	,	,
cord-024061-gxv8y146	86	9	for	for	IN
cord-024061-gxv8y146	86	10	example	example	NN
cord-024061-gxv8y146	86	11	,	,	,
cord-024061-gxv8y146	86	12	in	in	IN
cord-024061-gxv8y146	86	13	terms	term	NNS
cord-024061-gxv8y146	86	14	of	of	IN
cord-024061-gxv8y146	86	15	the	the	DT
cord-024061-gxv8y146	86	16	choice	choice	NN
cord-024061-gxv8y146	86	17	of	of	IN
cord-024061-gxv8y146	86	18	alignment	alignment	NN
cord-024061-gxv8y146	86	19	algorithm	algorithm	NN
cord-024061-gxv8y146	86	20	can	can	MD
cord-024061-gxv8y146	86	21	affect	affect	VB
cord-024061-gxv8y146	86	22	the	the	DT
cord-024061-gxv8y146	86	23	subsequent	subsequent	JJ
cord-024061-gxv8y146	86	24	phylogenetic	phylogenetic	JJ
cord-024061-gxv8y146	86	25	inferences	inference	NNS
cord-024061-gxv8y146	86	26	,	,	,
cord-024061-gxv8y146	86	27	such	such	JJ
cord-024061-gxv8y146	86	28	as	as	IN
cord-024061-gxv8y146	86	29	tree	tree	NN
cord-024061-gxv8y146	86	30	topology	topology	NN
cord-024061-gxv8y146	86	31	(	(	-LRB-
cord-024061-gxv8y146	86	32	46	46	CD
cord-024061-gxv8y146	86	33	)	)	-RRB-
cord-024061-gxv8y146	86	34	.	.	.
cord-024061-gxv8y146	87	1	However	however	RB
cord-024061-gxv8y146	87	2	,	,	,
cord-024061-gxv8y146	87	3	the	the	DT
cord-024061-gxv8y146	87	4	impacts	impact	NNS
cord-024061-gxv8y146	87	5	of	of	IN
cord-024061-gxv8y146	87	6	alignment	alignment	NN
cord-024061-gxv8y146	87	7	uncertainties	uncertainty	NNS
cord-024061-gxv8y146	87	8	have	have	VBP
cord-024061-gxv8y146	87	9	not	not	RB
cord-024061-gxv8y146	87	10	been	be	VBN
cord-024061-gxv8y146	87	11	reported	report	VBN
cord-024061-gxv8y146	87	12	with	with	IN
cord-024061-gxv8y146	87	13	simple	simple	JJ
cord-024061-gxv8y146	87	14	pathogens	pathogen	NNS
cord-024061-gxv8y146	87	15	like	like	IN
cord-024061-gxv8y146	87	16	viruses	virus	NNS
cord-024061-gxv8y146	87	17	,	,	,
cord-024061-gxv8y146	87	18	mainly	mainly	RB
cord-024061-gxv8y146	87	19	when	when	WRB
cord-024061-gxv8y146	87	20	dealing	deal	VBG
cord-024061-gxv8y146	87	21	with	with	IN
cord-024061-gxv8y146	87	22	small	small	JJ
cord-024061-gxv8y146	87	23	gene	gene	NN
cord-024061-gxv8y146	87	24	segments	segment	NNS
cord-024061-gxv8y146	87	25	.	.	.
cord-024061-gxv8y146	88	1	Therefore	therefore	RB
cord-024061-gxv8y146	88	2	,	,	,
cord-024061-gxv8y146	88	3	this	this	DT
cord-024061-gxv8y146	88	4	issue	issue	NN
cord-024061-gxv8y146	88	5	might	may	MD
cord-024061-gxv8y146	88	6	be	be	VB
cord-024061-gxv8y146	88	7	considered	consider	VBN
cord-024061-gxv8y146	88	8	when	when	WRB
cord-024061-gxv8y146	88	9	dealing	deal	VBG
cord-024061-gxv8y146	88	10	with	with	IN
cord-024061-gxv8y146	88	11	whole	whole	JJ
cord-024061-gxv8y146	88	12	genomes	genome	NNS
cord-024061-gxv8y146	88	13	or	or	CC
cord-024061-gxv8y146	88	14	with	with	IN
cord-024061-gxv8y146	88	15	more	more	JJR
cord-024061-gxv8y146	88	16	complex	complex	JJ
cord-024061-gxv8y146	88	17	pathogens	pathogen	NNS
cord-024061-gxv8y146	88	18	like	like	IN
cord-024061-gxv8y146	88	19	bacteria	bacteria	NNS
cord-024061-gxv8y146	88	20	and	and	CC
cord-024061-gxv8y146	88	21	fungi	fungus	NNS
cord-024061-gxv8y146	88	22	,	,	,
cord-024061-gxv8y146	88	23	which	which	WDT
cord-024061-gxv8y146	88	24	can	can	MD
cord-024061-gxv8y146	88	25	be	be	VB
cord-024061-gxv8y146	88	26	resolved	resolve	VBN
cord-024061-gxv8y146	88	27	by	by	IN
cord-024061-gxv8y146	88	28	multiple	multiple	JJ
cord-024061-gxv8y146	88	29	sequence	sequence	NN
cord-024061-gxv8y146	88	30	alignment	alignment	NN
cord-024061-gxv8y146	88	31	averaging	average	VBG
cord-024061-gxv8y146	88	32	using	use	VBG
cord-024061-gxv8y146	88	33	different	different	JJ
cord-024061-gxv8y146	88	34	alignment	alignment	NN
cord-024061-gxv8y146	88	35	algorithms	algorithm	NNS
cord-024061-gxv8y146	88	36	(	(	-LRB-
cord-024061-gxv8y146	88	37	47	47	CD
cord-024061-gxv8y146	88	38	)	)	-RRB-
cord-024061-gxv8y146	88	39	.	.	.
cord-024061-gxv8y146	89	1	Common	common	JJ
cord-024061-gxv8y146	89	2	alignment	alignment	NN
cord-024061-gxv8y146	89	3	algorithms	algorithm	NNS
cord-024061-gxv8y146	89	4	include	include	VBP
cord-024061-gxv8y146	89	5	CLUSTAL	CLUSTAL	NNP
cord-024061-gxv8y146	89	6	(	(	-LRB-
cord-024061-gxv8y146	89	7	48	48	CD
cord-024061-gxv8y146	89	8	)	)	-RRB-
cord-024061-gxv8y146	89	9	,	,	,
cord-024061-gxv8y146	89	10	T	t	NN
cord-024061-gxv8y146	89	11	-	-	HYPH
cord-024061-gxv8y146	89	12	coffee	coffee	NN
cord-024061-gxv8y146	89	13	(	(	-LRB-
cord-024061-gxv8y146	89	14	49	49	CD
cord-024061-gxv8y146	89	15	)	)	-RRB-
cord-024061-gxv8y146	89	16	,	,	,
cord-024061-gxv8y146	89	17	and	and	CC
cord-024061-gxv8y146	89	18	MUSCLE	MUSCLE	NNP
cord-024061-gxv8y146	89	19	(	(	-LRB-
cord-024061-gxv8y146	89	20	50	50	CD
cord-024061-gxv8y146	89	21	)	)	-RRB-
cord-024061-gxv8y146	89	22	,	,	,
cord-024061-gxv8y146	89	23	while	while	IN
cord-024061-gxv8y146	89	24	AliView	AliView	NNP
cord-024061-gxv8y146	89	25	is	be	VBZ
cord-024061-gxv8y146	89	26	a	a	DT
cord-024061-gxv8y146	89	27	user	user	NN
cord-024061-gxv8y146	89	28	-	-	HYPH
cord-024061-gxv8y146	89	29	friendly	friendly	JJ
cord-024061-gxv8y146	89	30	graphical	graphical	JJ
cord-024061-gxv8y146	89	31	interface	interface	NN
cord-024061-gxv8y146	89	32	that	that	WDT
cord-024061-gxv8y146	89	33	can	can	MD
cord-024061-gxv8y146	89	34	deal	deal	VB
cord-024061-gxv8y146	89	35	with	with	IN
cord-024061-gxv8y146	89	36	large	large	JJ
cord-024061-gxv8y146	89	37	sequence	sequence	NN
cord-024061-gxv8y146	89	38	datasets	dataset	NNS
cord-024061-gxv8y146	89	39	and	and	CC
cord-024061-gxv8y146	89	40	integrate	integrate	VB
cord-024061-gxv8y146	89	41	multiple	multiple	JJ
cord-024061-gxv8y146	89	42	alignment	alignment	NN
cord-024061-gxv8y146	89	43	algorithms	algorithm	NNS
cord-024061-gxv8y146	89	44	(	(	-LRB-
cord-024061-gxv8y146	89	45	51	51	CD
cord-024061-gxv8y146	89	46	)	)	-RRB-
cord-024061-gxv8y146	89	47	.	.	.
cord-024061-gxv8y146	90	1	Performing	perform	VBG
cord-024061-gxv8y146	90	2	the	the	DT
cord-024061-gxv8y146	90	3	multisequence	multisequence	NN
cord-024061-gxv8y146	90	4	alignment	alignment	NN
cord-024061-gxv8y146	90	5	using	use	VBG
cord-024061-gxv8y146	90	6	an	an	DT
cord-024061-gxv8y146	90	7	algorithm	algorithm	NN
cord-024061-gxv8y146	90	8	,	,	,
cord-024061-gxv8y146	90	9	and	and	CC
cord-024061-gxv8y146	90	10	manually	manually	RB
cord-024061-gxv8y146	90	11	deleting	delete	VBG
cord-024061-gxv8y146	90	12	the	the	DT
cord-024061-gxv8y146	90	13	gaps	gap	NNS
cord-024061-gxv8y146	90	14	within	within	IN
cord-024061-gxv8y146	90	15	the	the	DT
cord-024061-gxv8y146	90	16	translated	translate	VBN
cord-024061-gxv8y146	90	17	alignment	alignment	NN
cord-024061-gxv8y146	90	18	,	,	,
cord-024061-gxv8y146	90	19	are	be	VBP
cord-024061-gxv8y146	90	20	the	the	DT
cord-024061-gxv8y146	90	21	most	most	RBS
cord-024061-gxv8y146	90	22	common	common	JJ
cord-024061-gxv8y146	90	23	steps	step	NNS
cord-024061-gxv8y146	90	24	for	for	IN
cord-024061-gxv8y146	90	25	most	most	JJS
cord-024061-gxv8y146	90	26	phylogenetic	phylogenetic	JJ
cord-024061-gxv8y146	90	27	studies	study	NNS
cord-024061-gxv8y146	90	28	(	(	-LRB-
cord-024061-gxv8y146	90	29	51	51	CD
cord-024061-gxv8y146	90	30	)	)	-RRB-
cord-024061-gxv8y146	90	31	.	.	.
cord-024061-gxv8y146	91	1	Also	also	RB
cord-024061-gxv8y146	91	2	,	,	,
cord-024061-gxv8y146	91	3	confirming	confirm	VBG
cord-024061-gxv8y146	91	4	the	the	DT
cord-024061-gxv8y146	91	5	reading	reading	NN
cord-024061-gxv8y146	91	6	frame	frame	NN
cord-024061-gxv8y146	91	7	of	of	IN
cord-024061-gxv8y146	91	8	each	each	DT
cord-024061-gxv8y146	91	9	gene	gene	NN
cord-024061-gxv8y146	91	10	segment	segment	NN
cord-024061-gxv8y146	91	11	(	(	-LRB-
cord-024061-gxv8y146	91	12	excluding	exclude	VBG
cord-024061-gxv8y146	91	13	the	the	DT
cord-024061-gxv8y146	91	14	5	5	CD
cord-024061-gxv8y146	91	15	′	′	CD
cord-024061-gxv8y146	91	16	UTR	UTR	NNP
cord-024061-gxv8y146	91	17	)	)	-RRB-
cord-024061-gxv8y146	91	18	by	by	IN
cord-024061-gxv8y146	91	19	examining	examine	VBG
cord-024061-gxv8y146	91	20	the	the	DT
cord-024061-gxv8y146	91	21	amino	amino	NN
cord-024061-gxv8y146	91	22	acid	acid	NN
cord-024061-gxv8y146	91	23	translation	translation	NN
cord-024061-gxv8y146	91	24	is	be	VBZ
cord-024061-gxv8y146	91	25	another	another	DT
cord-024061-gxv8y146	91	26	step	step	NN
cord-024061-gxv8y146	91	27	within	within	IN
cord-024061-gxv8y146	91	28	the	the	DT
cord-024061-gxv8y146	91	29	MSA	MSA	NNP
cord-024061-gxv8y146	91	30	procedure	procedure	NN
cord-024061-gxv8y146	91	31	.	.	.
cord-024061-gxv8y146	92	1	This	this	DT
cord-024061-gxv8y146	92	2	step	step	NN
cord-024061-gxv8y146	92	3	is	be	VBZ
cord-024061-gxv8y146	92	4	commonly	commonly	RB
cord-024061-gxv8y146	92	5	done	do	VBN
cord-024061-gxv8y146	92	6	,	,	,
cord-024061-gxv8y146	92	7	for	for	IN
cord-024061-gxv8y146	92	8	example	example	NN
cord-024061-gxv8y146	92	9	,	,	,
cord-024061-gxv8y146	92	10	for	for	IN
cord-024061-gxv8y146	92	11	influenza	influenza	NN
cord-024061-gxv8y146	92	12	virus	virus	NN
cord-024061-gxv8y146	92	13	HA	HA	NNP
cord-024061-gxv8y146	92	14	and	and	CC
cord-024061-gxv8y146	92	15	PB2	PB2	NNP
cord-024061-gxv8y146	92	16	gene	gene	NN
cord-024061-gxv8y146	92	17	segments	segment	NNS
cord-024061-gxv8y146	92	18	,	,	,
cord-024061-gxv8y146	92	19	and	and	CC
cord-024061-gxv8y146	92	20	potentially	potentially	RB
cord-024061-gxv8y146	92	21	for	for	IN
cord-024061-gxv8y146	92	22	segments	segment	NNS
cord-024061-gxv8y146	92	23	7	7	CD
cord-024061-gxv8y146	92	24	and	and	CC
cord-024061-gxv8y146	92	25	8	8	CD
cord-024061-gxv8y146	92	26	,	,	,
cord-024061-gxv8y146	92	27	to	to	TO
cord-024061-gxv8y146	92	28	account	account	VB
cord-024061-gxv8y146	92	29	for	for	IN
cord-024061-gxv8y146	92	30	the	the	DT
cord-024061-gxv8y146	92	31	frameshifted	frameshifted	JJ
cord-024061-gxv8y146	92	32	M2	M2	NNP
cord-024061-gxv8y146	92	33	and	and	CC
cord-024061-gxv8y146	92	34	NS2	NS2	NNP
cord-024061-gxv8y146	92	35	genes	gene	NNS
cord-024061-gxv8y146	92	36	.	.	.
cord-024061-gxv8y146	93	1	However	however	RB
cord-024061-gxv8y146	93	2	,	,	,
cord-024061-gxv8y146	93	3	it	-PRON-	PRP
cord-024061-gxv8y146	93	4	is	be	VBZ
cord-024061-gxv8y146	93	5	worth	worth	JJ
cord-024061-gxv8y146	93	6	noting	note	VBG
cord-024061-gxv8y146	93	7	that	that	IN
cord-024061-gxv8y146	93	8	this	this	DT
cord-024061-gxv8y146	93	9	step	step	NN
cord-024061-gxv8y146	93	10	is	be	VBZ
cord-024061-gxv8y146	93	11	only	only	RB
cord-024061-gxv8y146	93	12	important	important	JJ
cord-024061-gxv8y146	93	13	for	for	IN
cord-024061-gxv8y146	93	14	partitioned	partition	VBN
cord-024061-gxv8y146	93	15	nucleotide	nucleotide	JJ
cord-024061-gxv8y146	93	16	models	model	NNS
cord-024061-gxv8y146	93	17	,	,	,
cord-024061-gxv8y146	93	18	described	describe	VBN
cord-024061-gxv8y146	93	19	below	below	RB
cord-024061-gxv8y146	93	20	.	.	.
cord-024061-gxv8y146	94	1	Phylodynamic	phylodynamic	NN
cord-024061-gxv8y146	94	2	analyses	analysis	NNS
cord-024061-gxv8y146	94	3	require	require	VBP
cord-024061-gxv8y146	94	4	both	both	DT
cord-024061-gxv8y146	94	5	time	time	NN
cord-024061-gxv8y146	94	6	and	and	CC
cord-024061-gxv8y146	94	7	computational	computational	JJ
cord-024061-gxv8y146	94	8	resources	resource	NNS
cord-024061-gxv8y146	94	9	,	,	,
cord-024061-gxv8y146	94	10	and	and	CC
cord-024061-gxv8y146	94	11	therefore	therefore	RB
cord-024061-gxv8y146	94	12	,	,	,
cord-024061-gxv8y146	94	13	conducting	conduct	VBG
cord-024061-gxv8y146	94	14	exploratory	exploratory	JJ
cord-024061-gxv8y146	94	15	phylogenetic	phylogenetic	JJ
cord-024061-gxv8y146	94	16	analyses	analysis	NNS
cord-024061-gxv8y146	94	17	using	use	VBG
cord-024061-gxv8y146	94	18	classical	classical	JJ
cord-024061-gxv8y146	94	19	methods	method	NNS
cord-024061-gxv8y146	94	20	is	be	VBZ
cord-024061-gxv8y146	94	21	an	an	DT
cord-024061-gxv8y146	94	22	essential	essential	JJ
cord-024061-gxv8y146	94	23	step	step	NN
cord-024061-gxv8y146	94	24	that	that	WDT
cord-024061-gxv8y146	94	25	will	will	MD
cord-024061-gxv8y146	94	26	ensure	ensure	VB
cord-024061-gxv8y146	94	27	the	the	DT
cord-024061-gxv8y146	94	28	proper	proper	JJ
cord-024061-gxv8y146	94	29	setup	setup	NN
cord-024061-gxv8y146	94	30	of	of	IN
cord-024061-gxv8y146	94	31	the	the	DT
cord-024061-gxv8y146	94	32	subsequent	subsequent	JJ
cord-024061-gxv8y146	94	33	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	94	34	models	model	NNS
cord-024061-gxv8y146	94	35	'	'	POS
cord-024061-gxv8y146	94	36	priors	prior	NNS
cord-024061-gxv8y146	94	37	.	.	.
cord-024061-gxv8y146	95	1	Classical	classical	JJ
cord-024061-gxv8y146	95	2	methods	method	NNS
cord-024061-gxv8y146	95	3	for	for	IN
cord-024061-gxv8y146	95	4	inferring	infer	VBG
cord-024061-gxv8y146	95	5	basic	basic	JJ
cord-024061-gxv8y146	95	6	phylogenetic	phylogenetic	JJ
cord-024061-gxv8y146	95	7	trees	tree	NNS
cord-024061-gxv8y146	95	8	(	(	-LRB-
cord-024061-gxv8y146	95	9	i.e.	i.e.	FW
cord-024061-gxv8y146	95	10	,	,	,
cord-024061-gxv8y146	95	11	non	non	JJ
cord-024061-gxv8y146	95	12	-	-	JJ
cord-024061-gxv8y146	95	13	time	time	JJ
cord-024061-gxv8y146	95	14	-	-	HYPH
cord-024061-gxv8y146	95	15	stamped	stamp	VBN
cord-024061-gxv8y146	95	16	trees	tree	NNS
cord-024061-gxv8y146	95	17	)	)	-RRB-
cord-024061-gxv8y146	95	18	include	include	VBP
cord-024061-gxv8y146	95	19	the	the	DT
cord-024061-gxv8y146	95	20	maximum	maximum	JJ
cord-024061-gxv8y146	95	21	likelihood	likelihood	NN
cord-024061-gxv8y146	95	22	(	(	-LRB-
cord-024061-gxv8y146	95	23	ML	ml	NN
cord-024061-gxv8y146	95	24	)	)	-RRB-
cord-024061-gxv8y146	95	25	(	(	-LRB-
cord-024061-gxv8y146	95	26	52	52	CD
cord-024061-gxv8y146	95	27	)	)	-RRB-
cord-024061-gxv8y146	95	28	,	,	,
cord-024061-gxv8y146	95	29	maximum	maximum	JJ
cord-024061-gxv8y146	95	30	parsimony	parsimony	NN
cord-024061-gxv8y146	95	31	(	(	-LRB-
cord-024061-gxv8y146	95	32	MP	MP	NNP
cord-024061-gxv8y146	95	33	)	)	-RRB-
cord-024061-gxv8y146	95	34	(	(	-LRB-
cord-024061-gxv8y146	95	35	53	53	CD
cord-024061-gxv8y146	95	36	)	)	-RRB-
cord-024061-gxv8y146	95	37	,	,	,
cord-024061-gxv8y146	95	38	and	and	CC
cord-024061-gxv8y146	95	39	neighborjoining	neighborjoining	NN
cord-024061-gxv8y146	95	40	(	(	-LRB-
cord-024061-gxv8y146	95	41	54	54	CD
cord-024061-gxv8y146	95	42	)	)	-RRB-
cord-024061-gxv8y146	95	43	algorithms	algorithm	NNS
cord-024061-gxv8y146	95	44	.	.	.
cord-024061-gxv8y146	96	1	Inferring	infer	VBG
cord-024061-gxv8y146	96	2	the	the	DT
cord-024061-gxv8y146	96	3	basic	basic	JJ
cord-024061-gxv8y146	96	4	phylogenetic	phylogenetic	JJ
cord-024061-gxv8y146	96	5	tree	tree	NN
cord-024061-gxv8y146	96	6	of	of	IN
cord-024061-gxv8y146	96	7	a	a	DT
cord-024061-gxv8y146	96	8	sequence	sequence	NN
cord-024061-gxv8y146	96	9	dataset	dataset	NN
cord-024061-gxv8y146	96	10	will	will	MD
cord-024061-gxv8y146	96	11	help	help	VB
cord-024061-gxv8y146	96	12	in	in	IN
cord-024061-gxv8y146	96	13	the	the	DT
cord-024061-gxv8y146	96	14	preliminary	preliminary	JJ
cord-024061-gxv8y146	96	15	assessment	assessment	NN
cord-024061-gxv8y146	96	16	of	of	IN
cord-024061-gxv8y146	96	17	the	the	DT
cord-024061-gxv8y146	96	18	tree	tree	NN
cord-024061-gxv8y146	96	19	's	's	POS
cord-024061-gxv8y146	96	20	topology	topology	NN
cord-024061-gxv8y146	96	21	in	in	IN
cord-024061-gxv8y146	96	22	terms	term	NNS
cord-024061-gxv8y146	96	23	of	of	IN
cord-024061-gxv8y146	96	24	the	the	DT
cord-024061-gxv8y146	96	25	magnitude	magnitude	NN
cord-024061-gxv8y146	96	26	of	of	IN
cord-024061-gxv8y146	96	27	structure	structure	NN
cord-024061-gxv8y146	96	28	across	across	IN
cord-024061-gxv8y146	96	29	branches	branch	NNS
cord-024061-gxv8y146	96	30	,	,	,
cord-024061-gxv8y146	96	31	degree	degree	NN
cord-024061-gxv8y146	96	32	of	of	IN
cord-024061-gxv8y146	96	33	topological	topological	JJ
cord-024061-gxv8y146	96	34	(	(	-LRB-
cord-024061-gxv8y146	96	35	in)congruence	in)congruence	NN
cord-024061-gxv8y146	96	36	between	between	IN
cord-024061-gxv8y146	96	37	different	different	JJ
cord-024061-gxv8y146	96	38	gene	gene	NN
cord-024061-gxv8y146	96	39	segments	segment	NNS
cord-024061-gxv8y146	96	40	,	,	,
cord-024061-gxv8y146	96	41	and	and	CC
cord-024061-gxv8y146	96	42	selection	selection	NN
cord-024061-gxv8y146	96	43	of	of	IN
cord-024061-gxv8y146	96	44	lineages	lineage	NNS
cord-024061-gxv8y146	96	45	(	(	-LRB-
cord-024061-gxv8y146	96	46	in	in	IN
cord-024061-gxv8y146	96	47	large	large	JJ
cord-024061-gxv8y146	96	48	datasets	dataset	NNS
cord-024061-gxv8y146	96	49	)	)	-RRB-
cord-024061-gxv8y146	96	50	for	for	IN
cord-024061-gxv8y146	96	51	the	the	DT
cord-024061-gxv8y146	96	52	subsequent	subsequent	JJ
cord-024061-gxv8y146	96	53	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	96	54	analyses	analysis	NNS
cord-024061-gxv8y146	96	55	.	.	.
cord-024061-gxv8y146	97	1	Classical	classical	JJ
cord-024061-gxv8y146	97	2	phylogenetic	phylogenetic	NN
cord-024061-gxv8y146	97	3	algorithms	algorithm	NNS
cord-024061-gxv8y146	97	4	are	be	VBP
cord-024061-gxv8y146	97	5	implemented	implement	VBN
cord-024061-gxv8y146	97	6	in	in	IN
cord-024061-gxv8y146	97	7	many	many	JJ
cord-024061-gxv8y146	97	8	open	open	JJ
cord-024061-gxv8y146	97	9	-	-	HYPH
cord-024061-gxv8y146	97	10	source	source	NN
cord-024061-gxv8y146	97	11	software	software	NN
cord-024061-gxv8y146	97	12	packages	package	NNS
cord-024061-gxv8y146	97	13	such	such	JJ
cord-024061-gxv8y146	97	14	as	as	IN
cord-024061-gxv8y146	97	15	MEGA	MEGA	NNP
cord-024061-gxv8y146	97	16	(	(	-LRB-
cord-024061-gxv8y146	97	17	55	55	CD
cord-024061-gxv8y146	97	18	)	)	-RRB-
cord-024061-gxv8y146	97	19	and	and	CC
cord-024061-gxv8y146	97	20	RaXML	RaXML	NNP
cord-024061-gxv8y146	97	21	(	(	-LRB-
cord-024061-gxv8y146	97	22	56	56	CD
cord-024061-gxv8y146	97	23	)	)	-RRB-
cord-024061-gxv8y146	97	24	.	.	.
cord-024061-gxv8y146	98	1	The	the	DT
cord-024061-gxv8y146	98	2	rapid	rapid	JJ
cord-024061-gxv8y146	98	3	spread	spread	NN
cord-024061-gxv8y146	98	4	and	and	CC
cord-024061-gxv8y146	98	5	transmission	transmission	NN
cord-024061-gxv8y146	98	6	of	of	IN
cord-024061-gxv8y146	98	7	viral	viral	JJ
cord-024061-gxv8y146	98	8	diseases	disease	NNS
cord-024061-gxv8y146	98	9	during	during	IN
cord-024061-gxv8y146	98	10	epidemics	epidemic	NNS
cord-024061-gxv8y146	98	11	provide	provide	VBP
cord-024061-gxv8y146	98	12	plenty	plenty	NN
cord-024061-gxv8y146	98	13	of	of	IN
cord-024061-gxv8y146	98	14	time	time	NN
cord-024061-gxv8y146	98	15	for	for	IN
cord-024061-gxv8y146	98	16	the	the	DT
cord-024061-gxv8y146	98	17	pathogen	pathogen	NN
cord-024061-gxv8y146	98	18	to	to	TO
cord-024061-gxv8y146	98	19	accumulate	accumulate	VB
cord-024061-gxv8y146	98	20	informative	informative	JJ
cord-024061-gxv8y146	98	21	mutations	mutation	NNS
cord-024061-gxv8y146	98	22	in	in	IN
cord-024061-gxv8y146	98	23	their	-PRON-	PRP$
cord-024061-gxv8y146	98	24	genomes	genome	NNS
cord-024061-gxv8y146	98	25	(	(	-LRB-
cord-024061-gxv8y146	98	26	57	57	CD
cord-024061-gxv8y146	98	27	)	)	-RRB-
cord-024061-gxv8y146	98	28	.	.	.
cord-024061-gxv8y146	99	1	Therefore	therefore	RB
cord-024061-gxv8y146	99	2	,	,	,
cord-024061-gxv8y146	99	3	100	100	CD
cord-024061-gxv8y146	99	4	%	%	NN
cord-024061-gxv8y146	99	5	identical	identical	JJ
cord-024061-gxv8y146	99	6	sequences	sequence	NNS
cord-024061-gxv8y146	99	7	within	within	IN
cord-024061-gxv8y146	99	8	a	a	DT
cord-024061-gxv8y146	99	9	dataset	dataset	NN
cord-024061-gxv8y146	99	10	dilute	dilute	VB
cord-024061-gxv8y146	99	11	such	such	JJ
cord-024061-gxv8y146	99	12	information	information	NN
cord-024061-gxv8y146	99	13	.	.	.
cord-024061-gxv8y146	100	1	Also	also	RB
cord-024061-gxv8y146	100	2	,	,	,
cord-024061-gxv8y146	100	3	retrieved	retrieve	VBD
cord-024061-gxv8y146	100	4	sequence	sequence	NN
cord-024061-gxv8y146	100	5	datasets	dataset	NNS
cord-024061-gxv8y146	100	6	suffer	suffer	VBP
cord-024061-gxv8y146	100	7	from	from	IN
cord-024061-gxv8y146	100	8	inherent	inherent	JJ
cord-024061-gxv8y146	100	9	redundancy	redundancy	NN
cord-024061-gxv8y146	100	10	due	due	JJ
cord-024061-gxv8y146	100	11	to	to	IN
cord-024061-gxv8y146	100	12	sampling	sampling	NN
cord-024061-gxv8y146	100	13	bias	bias	NN
cord-024061-gxv8y146	100	14	and	and	CC
cord-024061-gxv8y146	100	15	issues	issue	NNS
cord-024061-gxv8y146	100	16	related	relate	VBN
cord-024061-gxv8y146	100	17	to	to	IN
cord-024061-gxv8y146	100	18	the	the	DT
cord-024061-gxv8y146	100	19	sequencing	sequencing	NN
cord-024061-gxv8y146	100	20	procedure	procedure	NN
cord-024061-gxv8y146	100	21	(	(	-LRB-
cord-024061-gxv8y146	100	22	58	58	CD
cord-024061-gxv8y146	100	23	)	)	-RRB-
cord-024061-gxv8y146	100	24	.	.	.
cord-024061-gxv8y146	101	1	Hence	hence	RB
cord-024061-gxv8y146	101	2	,	,	,
cord-024061-gxv8y146	101	3	removing	remove	VBG
cord-024061-gxv8y146	101	4	100	100	CD
cord-024061-gxv8y146	101	5	%	%	NN
cord-024061-gxv8y146	101	6	identical	identical	JJ
cord-024061-gxv8y146	101	7	sequences	sequence	NNS
cord-024061-gxv8y146	101	8	from	from	IN
cord-024061-gxv8y146	101	9	the	the	DT
cord-024061-gxv8y146	101	10	dataset	dataset	NN
cord-024061-gxv8y146	101	11	under	under	IN
cord-024061-gxv8y146	101	12	study	study	NN
cord-024061-gxv8y146	101	13	,	,	,
cord-024061-gxv8y146	101	14	will	will	MD
cord-024061-gxv8y146	101	15	reduce	reduce	VB
cord-024061-gxv8y146	101	16	the	the	DT
cord-024061-gxv8y146	101	17	impact	impact	NN
cord-024061-gxv8y146	101	18	of	of	IN
cord-024061-gxv8y146	101	19	such	such	JJ
cord-024061-gxv8y146	101	20	redundancies	redundancy	NNS
cord-024061-gxv8y146	101	21	,	,	,
cord-024061-gxv8y146	101	22	strengthen	strengthen	VB
cord-024061-gxv8y146	101	23	the	the	DT
cord-024061-gxv8y146	101	24	tree	tree	NN
cord-024061-gxv8y146	101	25	structure	structure	NN
cord-024061-gxv8y146	101	26	,	,	,
cord-024061-gxv8y146	101	27	and	and	CC
cord-024061-gxv8y146	101	28	shorten	shorten	VB
cord-024061-gxv8y146	101	29	the	the	DT
cord-024061-gxv8y146	101	30	computational	computational	JJ
cord-024061-gxv8y146	101	31	time	time	NN
cord-024061-gxv8y146	101	32	.	.	.
cord-024061-gxv8y146	102	1	Furthermore	furthermore	RB
cord-024061-gxv8y146	102	2	,	,	,
cord-024061-gxv8y146	102	3	if	if	IN
cord-024061-gxv8y146	102	4	the	the	DT
cord-024061-gxv8y146	102	5	proportion	proportion	NN
cord-024061-gxv8y146	102	6	of	of	IN
cord-024061-gxv8y146	102	7	100	100	CD
cord-024061-gxv8y146	102	8	%	%	NN
cord-024061-gxv8y146	102	9	identical	identical	JJ
cord-024061-gxv8y146	102	10	sequences	sequence	NNS
cord-024061-gxv8y146	102	11	was	be	VBD
cord-024061-gxv8y146	102	12	substantially	substantially	RB
cord-024061-gxv8y146	102	13	large	large	JJ
cord-024061-gxv8y146	102	14	,	,	,
cord-024061-gxv8y146	102	15	it	-PRON-	PRP
cord-024061-gxv8y146	102	16	will	will	MD
cord-024061-gxv8y146	102	17	typically	typically	RB
cord-024061-gxv8y146	102	18	lead	lead	VB
cord-024061-gxv8y146	102	19	to	to	IN
cord-024061-gxv8y146	102	20	weaker	weak	JJR
cord-024061-gxv8y146	102	21	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	102	22	signals	signal	NNS
cord-024061-gxv8y146	102	23	and	and	CC
cord-024061-gxv8y146	102	24	subsequently	subsequently	RB
cord-024061-gxv8y146	102	25	poorer	poor	JJR
cord-024061-gxv8y146	102	26	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	102	27	model	model	NN
cord-024061-gxv8y146	102	28	convergence	convergence	NN
cord-024061-gxv8y146	102	29	.	.	.
cord-024061-gxv8y146	103	1	Recombination	recombination	NN
cord-024061-gxv8y146	103	2	is	be	VBZ
cord-024061-gxv8y146	103	3	a	a	DT
cord-024061-gxv8y146	103	4	natural	natural	JJ
cord-024061-gxv8y146	103	5	biological	biological	JJ
cord-024061-gxv8y146	103	6	phenomenon	phenomenon	NN
cord-024061-gxv8y146	103	7	of	of	IN
cord-024061-gxv8y146	103	8	rapidly	rapidly	RB
cord-024061-gxv8y146	103	9	evolving	evolve	VBG
cord-024061-gxv8y146	103	10	viruses	virus	NNS
cord-024061-gxv8y146	103	11	like	like	IN
cord-024061-gxv8y146	103	12	influenza	influenza	NN
cord-024061-gxv8y146	103	13	and	and	CC
cord-024061-gxv8y146	103	14	occurs	occur	VBZ
cord-024061-gxv8y146	103	15	when	when	WRB
cord-024061-gxv8y146	103	16	viral	viral	JJ
cord-024061-gxv8y146	103	17	genomes	genome	NNS
cord-024061-gxv8y146	103	18	co	co	VBD
cord-024061-gxv8y146	103	19	-	-	VBP
cord-024061-gxv8y146	103	20	infect	infect	VB
cord-024061-gxv8y146	103	21	the	the	DT
cord-024061-gxv8y146	103	22	same	same	JJ
cord-024061-gxv8y146	103	23	host	host	NN
cord-024061-gxv8y146	103	24	cell	cell	NN
cord-024061-gxv8y146	103	25	and	and	CC
cord-024061-gxv8y146	103	26	exchange	exchange	NN
cord-024061-gxv8y146	103	27	fragments	fragment	NNS
cord-024061-gxv8y146	103	28	of	of	IN
cord-024061-gxv8y146	103	29	their	-PRON-	PRP$
cord-024061-gxv8y146	103	30	gene	gene	NN
cord-024061-gxv8y146	103	31	segments	segment	NNS
cord-024061-gxv8y146	103	32	resulting	result	VBG
cord-024061-gxv8y146	103	33	in	in	IN
cord-024061-gxv8y146	103	34	new	new	JJ
cord-024061-gxv8y146	103	35	viral	viral	JJ
cord-024061-gxv8y146	103	36	strains	strain	NNS
cord-024061-gxv8y146	103	37	(	(	-LRB-
cord-024061-gxv8y146	103	38	59	59	CD
cord-024061-gxv8y146	103	39	)	)	-RRB-
cord-024061-gxv8y146	103	40	.	.	.
cord-024061-gxv8y146	104	1	Ignoring	ignore	VBG
cord-024061-gxv8y146	104	2	recombination	recombination	NN
cord-024061-gxv8y146	104	3	events	event	NNS
cord-024061-gxv8y146	104	4	in	in	IN
cord-024061-gxv8y146	104	5	a	a	DT
cord-024061-gxv8y146	104	6	sequence	sequence	NN
cord-024061-gxv8y146	104	7	dataset	dataset	NN
cord-024061-gxv8y146	104	8	may	may	MD
cord-024061-gxv8y146	104	9	advisedly	advisedly	RB
cord-024061-gxv8y146	104	10	bias	bias	VB
cord-024061-gxv8y146	104	11	the	the	DT
cord-024061-gxv8y146	104	12	inferred	infer	VBN
cord-024061-gxv8y146	104	13	posterior	posterior	JJ
cord-024061-gxv8y146	104	14	phylogenetic	phylogenetic	JJ
cord-024061-gxv8y146	104	15	relationships	relationship	NNS
cord-024061-gxv8y146	104	16	and	and	CC
cord-024061-gxv8y146	104	17	,	,	,
cord-024061-gxv8y146	104	18	therefore	therefore	RB
cord-024061-gxv8y146	104	19	,	,	,
cord-024061-gxv8y146	104	20	must	must	MD
cord-024061-gxv8y146	104	21	be	be	VB
cord-024061-gxv8y146	104	22	excluded	exclude	VBN
cord-024061-gxv8y146	104	23	(	(	-LRB-
cord-024061-gxv8y146	104	24	60	60	CD
cord-024061-gxv8y146	104	25	)	)	-RRB-
cord-024061-gxv8y146	104	26	.	.	.
cord-024061-gxv8y146	105	1	Recombination	recombination	NN
cord-024061-gxv8y146	105	2	events	event	NNS
cord-024061-gxv8y146	105	3	can	can	MD
cord-024061-gxv8y146	105	4	be	be	VB
cord-024061-gxv8y146	105	5	detected	detect	VBN
cord-024061-gxv8y146	105	6	using	use	VBG
cord-024061-gxv8y146	105	7	the	the	DT
cord-024061-gxv8y146	105	8	Recombination	Recombination	NNP
cord-024061-gxv8y146	105	9	Detection	Detection	NNP
cord-024061-gxv8y146	105	10	Program	Program	NNP
cord-024061-gxv8y146	105	11	(	(	-LRB-
cord-024061-gxv8y146	105	12	61	61	CD
cord-024061-gxv8y146	105	13	)	)	-RRB-
cord-024061-gxv8y146	105	14	.	.	.
cord-024061-gxv8y146	106	1	However	however	RB
cord-024061-gxv8y146	106	2	,	,	,
cord-024061-gxv8y146	106	3	recombination	recombination	NN
cord-024061-gxv8y146	106	4	events	event	NNS
cord-024061-gxv8y146	106	5	are	be	VBP
cord-024061-gxv8y146	106	6	more	more	RBR
cord-024061-gxv8y146	106	7	often	often	RB
cord-024061-gxv8y146	106	8	detected	detect	VBN
cord-024061-gxv8y146	106	9	in	in	IN
cord-024061-gxv8y146	106	10	whole	whole	JJ
cord-024061-gxv8y146	106	11	genomes	genome	NNS
cord-024061-gxv8y146	106	12	than	than	IN
cord-024061-gxv8y146	106	13	in	in	IN
cord-024061-gxv8y146	106	14	single	single	JJ
cord-024061-gxv8y146	106	15	-	-	HYPH
cord-024061-gxv8y146	106	16	gene	gene	NN
cord-024061-gxv8y146	106	17	segments	segment	NNS
cord-024061-gxv8y146	106	18	.	.	.
cord-024061-gxv8y146	107	1	Therefore	therefore	RB
cord-024061-gxv8y146	107	2	,	,	,
cord-024061-gxv8y146	107	3	conducting	conduct	VBG
cord-024061-gxv8y146	107	4	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	107	5	analyses	analysis	NNS
cord-024061-gxv8y146	107	6	on	on	IN
cord-024061-gxv8y146	107	7	whole	whole	JJ
cord-024061-gxv8y146	107	8	-	-	HYPH
cord-024061-gxv8y146	107	9	genome	genome	NN
cord-024061-gxv8y146	107	10	sequences	sequence	NNS
cord-024061-gxv8y146	107	11	only	only	RB
cord-024061-gxv8y146	107	12	will	will	MD
cord-024061-gxv8y146	107	13	lead	lead	VB
cord-024061-gxv8y146	107	14	to	to	IN
cord-024061-gxv8y146	107	15	the	the	DT
cord-024061-gxv8y146	107	16	exclusion	exclusion	NN
cord-024061-gxv8y146	107	17	of	of	IN
cord-024061-gxv8y146	107	18	many	many	JJ
cord-024061-gxv8y146	107	19	isolates	isolate	NNS
cord-024061-gxv8y146	107	20	resulting	result	VBG
cord-024061-gxv8y146	107	21	in	in	IN
cord-024061-gxv8y146	107	22	a	a	DT
cord-024061-gxv8y146	107	23	substantially	substantially	RB
cord-024061-gxv8y146	107	24	smaller	small	JJR
cord-024061-gxv8y146	107	25	dataset	dataset	NN
cord-024061-gxv8y146	107	26	and	and	CC
cord-024061-gxv8y146	107	27	subsequently	subsequently	RB
cord-024061-gxv8y146	107	28	biased	bias	VBD
cord-024061-gxv8y146	107	29	inferences	inference	NNS
cord-024061-gxv8y146	107	30	.	.	.
cord-024061-gxv8y146	108	1	Nevertheless	nevertheless	RB
cord-024061-gxv8y146	108	2	,	,	,
cord-024061-gxv8y146	108	3	the	the	DT
cord-024061-gxv8y146	108	4	occurrence	occurrence	NN
cord-024061-gxv8y146	108	5	of	of	IN
cord-024061-gxv8y146	108	6	recombination	recombination	NN
cord-024061-gxv8y146	108	7	events	event	NNS
cord-024061-gxv8y146	108	8	at	at	IN
cord-024061-gxv8y146	108	9	the	the	DT
cord-024061-gxv8y146	108	10	beginning	beginning	NN
cord-024061-gxv8y146	108	11	of	of	IN
cord-024061-gxv8y146	108	12	a	a	DT
cord-024061-gxv8y146	108	13	novel	novel	JJ
cord-024061-gxv8y146	108	14	viral	viral	JJ
cord-024061-gxv8y146	108	15	outbreak	outbreak	NN
cord-024061-gxv8y146	108	16	might	may	MD
cord-024061-gxv8y146	108	17	be	be	VB
cord-024061-gxv8y146	108	18	limited	limit	VBN
cord-024061-gxv8y146	108	19	.	.	.
cord-024061-gxv8y146	109	1	Assessing	assess	VBG
cord-024061-gxv8y146	109	2	the	the	DT
cord-024061-gxv8y146	109	3	magnitude	magnitude	NN
cord-024061-gxv8y146	109	4	of	of	IN
cord-024061-gxv8y146	109	5	temporal	temporal	JJ
cord-024061-gxv8y146	109	6	structure	structure	NN
cord-024061-gxv8y146	109	7	in	in	IN
cord-024061-gxv8y146	109	8	the	the	DT
cord-024061-gxv8y146	109	9	phylogeny	phylogeny	NN
cord-024061-gxv8y146	109	10	of	of	IN
cord-024061-gxv8y146	109	11	the	the	DT
cord-024061-gxv8y146	109	12	sequences	sequence	NNS
cord-024061-gxv8y146	109	13	data	datum	NNS
cord-024061-gxv8y146	109	14	collected	collect	VBN
cord-024061-gxv8y146	109	15	at	at	IN
cord-024061-gxv8y146	109	16	different	different	JJ
cord-024061-gxv8y146	109	17	points	point	NNS
cord-024061-gxv8y146	109	18	of	of	IN
cord-024061-gxv8y146	109	19	time	time	NN
cord-024061-gxv8y146	109	20	is	be	VBZ
cord-024061-gxv8y146	109	21	the	the	DT
cord-024061-gxv8y146	109	22	final	final	JJ
cord-024061-gxv8y146	109	23	recommended	recommend	VBN
cord-024061-gxv8y146	109	24	step	step	NN
cord-024061-gxv8y146	109	25	within	within	IN
cord-024061-gxv8y146	109	26	the	the	DT
cord-024061-gxv8y146	109	27	preliminary	preliminary	JJ
cord-024061-gxv8y146	109	28	phylogenetic	phylogenetic	JJ
cord-024061-gxv8y146	109	29	analyses	analysis	NNS
cord-024061-gxv8y146	109	30	stage	stage	NN
cord-024061-gxv8y146	109	31	(	(	-LRB-
cord-024061-gxv8y146	109	32	62	62	CD
cord-024061-gxv8y146	109	33	)	)	-RRB-
cord-024061-gxv8y146	109	34	.	.	.
cord-024061-gxv8y146	110	1	Here	here	RB
cord-024061-gxv8y146	110	2	,	,	,
cord-024061-gxv8y146	110	3	the	the	DT
cord-024061-gxv8y146	110	4	term	term	NN
cord-024061-gxv8y146	110	5	"	"	``
cord-024061-gxv8y146	110	6	temporal	temporal	JJ
cord-024061-gxv8y146	110	7	structure	structure	NN
cord-024061-gxv8y146	110	8	"	"	''
cord-024061-gxv8y146	110	9	is	be	VBZ
cord-024061-gxv8y146	110	10	defined	define	VBN
cord-024061-gxv8y146	110	11	as	as	IN
cord-024061-gxv8y146	110	12	the	the	DT
cord-024061-gxv8y146	110	13	measurable	measurable	JJ
cord-024061-gxv8y146	110	14	difference	difference	NN
cord-024061-gxv8y146	110	15	in	in	IN
cord-024061-gxv8y146	110	16	terms	term	NNS
cord-024061-gxv8y146	110	17	of	of	IN
cord-024061-gxv8y146	110	18	nucleotide	nucleotide	JJ
cord-024061-gxv8y146	110	19	or	or	CC
cord-024061-gxv8y146	110	20	amino	amino	NN
cord-024061-gxv8y146	110	21	acid	acid	NN
cord-024061-gxv8y146	110	22	substitution	substitution	NN
cord-024061-gxv8y146	110	23	between	between	IN
cord-024061-gxv8y146	110	24	two	two	CD
cord-024061-gxv8y146	110	25	genetic	genetic	JJ
cord-024061-gxv8y146	110	26	sequences	sequence	NNS
cord-024061-gxv8y146	110	27	sampled	sample	VBN
cord-024061-gxv8y146	110	28	at	at	IN
cord-024061-gxv8y146	110	29	two	two	CD
cord-024061-gxv8y146	110	30	distinct	distinct	JJ
cord-024061-gxv8y146	110	31	points	point	NNS
cord-024061-gxv8y146	110	32	of	of	IN
cord-024061-gxv8y146	110	33	time	time	NN
cord-024061-gxv8y146	110	34	(	(	-LRB-
cord-024061-gxv8y146	110	35	63	63	CD
cord-024061-gxv8y146	110	36	)	)	-RRB-
cord-024061-gxv8y146	110	37	.	.	.
cord-024061-gxv8y146	111	1	Therefore	therefore	RB
cord-024061-gxv8y146	111	2	,	,	,
cord-024061-gxv8y146	111	3	if	if	IN
cord-024061-gxv8y146	111	4	the	the	DT
cord-024061-gxv8y146	111	5	sequence	sequence	NN
cord-024061-gxv8y146	111	6	data	data	NN
cord-024061-gxv8y146	111	7	lacks	lack	VBZ
cord-024061-gxv8y146	111	8	sufficient	sufficient	JJ
cord-024061-gxv8y146	111	9	temporal	temporal	JJ
cord-024061-gxv8y146	111	10	structure	structure	NN
cord-024061-gxv8y146	111	11	,	,	,
cord-024061-gxv8y146	111	12	then	then	RB
cord-024061-gxv8y146	111	13	proceeding	proceed	VBG
cord-024061-gxv8y146	111	14	to	to	IN
cord-024061-gxv8y146	111	15	the	the	DT
cord-024061-gxv8y146	111	16	phylodynamic	phylodynamic	NNP
cord-024061-gxv8y146	111	17	analysis	analysis	NN
cord-024061-gxv8y146	111	18	may	may	MD
cord-024061-gxv8y146	111	19	lead	lead	VB
cord-024061-gxv8y146	111	20	to	to	IN
cord-024061-gxv8y146	111	21	biased	biased	JJ
cord-024061-gxv8y146	111	22	posterior	posterior	JJ
cord-024061-gxv8y146	111	23	estimates	estimate	NNS
cord-024061-gxv8y146	111	24	and	and	CC
cord-024061-gxv8y146	111	25	misleading	mislead	VBG
cord-024061-gxv8y146	111	26	conclusions	conclusion	NNS
cord-024061-gxv8y146	111	27	(	(	-LRB-
cord-024061-gxv8y146	111	28	62	62	CD
cord-024061-gxv8y146	111	29	)	)	-RRB-
cord-024061-gxv8y146	111	30	.	.	.
cord-024061-gxv8y146	112	1	An	an	DT
cord-024061-gxv8y146	112	2	interactive	interactive	JJ
cord-024061-gxv8y146	112	3	regression	regression	NN
cord-024061-gxv8y146	112	4	-	-	HYPH
cord-024061-gxv8y146	112	5	based	base	VBN
cord-024061-gxv8y146	112	6	approach	approach	NN
cord-024061-gxv8y146	112	7	is	be	VBZ
cord-024061-gxv8y146	112	8	implemented	implement	VBN
cord-024061-gxv8y146	112	9	in	in	IN
cord-024061-gxv8y146	112	10	the	the	DT
cord-024061-gxv8y146	112	11	TempEst	TempEst	NNP
cord-024061-gxv8y146	112	12	software	software	NN
cord-024061-gxv8y146	112	13	package	package	NN
cord-024061-gxv8y146	112	14	(	(	-LRB-
cord-024061-gxv8y146	112	15	62	62	CD
cord-024061-gxv8y146	112	16	)	)	-RRB-
cord-024061-gxv8y146	112	17	to	to	TO
cord-024061-gxv8y146	112	18	assess	assess	VB
cord-024061-gxv8y146	112	19	the	the	DT
cord-024061-gxv8y146	112	20	strength	strength	NN
cord-024061-gxv8y146	112	21	of	of	IN
cord-024061-gxv8y146	112	22	the	the	DT
cord-024061-gxv8y146	112	23	association	association	NN
cord-024061-gxv8y146	112	24	between	between	IN
cord-024061-gxv8y146	112	25	sequences	sequence	NNS
cord-024061-gxv8y146	112	26	'	'	POS
cord-024061-gxv8y146	112	27	sampling	sampling	NN
cord-024061-gxv8y146	112	28	dates	date	NNS
cord-024061-gxv8y146	112	29	and	and	CC
cord-024061-gxv8y146	112	30	genetic	genetic	JJ
cord-024061-gxv8y146	112	31	divergence	divergence	NN
cord-024061-gxv8y146	112	32	through	through	IN
cord-024061-gxv8y146	112	33	time	time	NN
cord-024061-gxv8y146	112	34	.	.	.
cord-024061-gxv8y146	113	1	R	r	NN
cord-024061-gxv8y146	113	2	2	2	CD
cord-024061-gxv8y146	113	3	values	value	NNS
cord-024061-gxv8y146	113	4	closer	close	RBR
cord-024061-gxv8y146	113	5	to	to	IN
cord-024061-gxv8y146	113	6	1	1	CD
cord-024061-gxv8y146	113	7	than	than	IN
cord-024061-gxv8y146	113	8	0	0	CD
cord-024061-gxv8y146	113	9	estimated	estimate	VBN
cord-024061-gxv8y146	113	10	from	from	IN
cord-024061-gxv8y146	113	11	a	a	DT
cord-024061-gxv8y146	113	12	time	time	NN
cord-024061-gxv8y146	113	13	-	-	HYPH
cord-024061-gxv8y146	113	14	stamped	stamp	VBN
cord-024061-gxv8y146	113	15	ML	ML	NNP
cord-024061-gxv8y146	113	16	tree	tree	NN
cord-024061-gxv8y146	113	17	using	use	VBG
cord-024061-gxv8y146	113	18	the	the	DT
cord-024061-gxv8y146	113	19	root	root	NN
cord-024061-gxv8y146	113	20	-	-	HYPH
cord-024061-gxv8y146	113	21	to	to	IN
cord-024061-gxv8y146	113	22	-	-	HYPH
cord-024061-gxv8y146	113	23	tip	tip	NN
cord-024061-gxv8y146	113	24	genetic	genetic	JJ
cord-024061-gxv8y146	113	25	distance	distance	NN
cord-024061-gxv8y146	113	26	linear	linear	JJ
cord-024061-gxv8y146	113	27	regression	regression	NN
cord-024061-gxv8y146	113	28	indicate	indicate	VBP
cord-024061-gxv8y146	113	29	a	a	DT
cord-024061-gxv8y146	113	30	strong	strong	JJ
cord-024061-gxv8y146	113	31	temporal	temporal	JJ
cord-024061-gxv8y146	113	32	structure	structure	NN
cord-024061-gxv8y146	113	33	(	(	-LRB-
cord-024061-gxv8y146	113	34	62	62	CD
cord-024061-gxv8y146	113	35	)	)	-RRB-
cord-024061-gxv8y146	113	36	.	.	.
cord-024061-gxv8y146	114	1	Finally	finally	RB
cord-024061-gxv8y146	114	2	,	,	,
cord-024061-gxv8y146	114	3	TempEst	TempEst	NNP
cord-024061-gxv8y146	114	4	can	can	MD
cord-024061-gxv8y146	114	5	identify	identify	VB
cord-024061-gxv8y146	114	6	incongruent	incongruent	JJ
cord-024061-gxv8y146	114	7	sequences	sequence	NNS
cord-024061-gxv8y146	114	8	that	that	WDT
cord-024061-gxv8y146	114	9	are	be	VBP
cord-024061-gxv8y146	114	10	defined	define	VBN
cord-024061-gxv8y146	114	11	as	as	IN
cord-024061-gxv8y146	114	12	outlier	outlier	JJ
cord-024061-gxv8y146	114	13	isolates	isolate	NNS
cord-024061-gxv8y146	114	14	that	that	WDT
cord-024061-gxv8y146	114	15	caused	cause	VBD
cord-024061-gxv8y146	114	16	substantially	substantially	RB
cord-024061-gxv8y146	114	17	more	more	RBR
cord-024061-gxv8y146	114	18	or	or	CC
cord-024061-gxv8y146	114	19	less	less	RBR
cord-024061-gxv8y146	114	20	genetic	genetic	JJ
cord-024061-gxv8y146	114	21	divergence	divergence	NN
cord-024061-gxv8y146	114	22	from	from	IN
cord-024061-gxv8y146	114	23	the	the	DT
cord-024061-gxv8y146	114	24	tip	tip	NN
cord-024061-gxv8y146	114	25	to	to	IN
cord-024061-gxv8y146	114	26	the	the	DT
cord-024061-gxv8y146	114	27	root	root	NN
cord-024061-gxv8y146	114	28	than	than	IN
cord-024061-gxv8y146	114	29	one	one	PRP
cord-024061-gxv8y146	114	30	would	would	MD
cord-024061-gxv8y146	114	31	expect	expect	VB
cord-024061-gxv8y146	114	32	given	give	VBN
cord-024061-gxv8y146	114	33	their	-PRON-	PRP$
cord-024061-gxv8y146	114	34	sampling	sampling	NN
cord-024061-gxv8y146	114	35	date	date	NN
cord-024061-gxv8y146	114	36	(	(	-LRB-
cord-024061-gxv8y146	114	37	62	62	CD
cord-024061-gxv8y146	114	38	)	)	-RRB-
cord-024061-gxv8y146	114	39	.	.	.
cord-024061-gxv8y146	115	1	Incongruent	Incongruent	NNP
cord-024061-gxv8y146	115	2	sequences	sequence	NNS
cord-024061-gxv8y146	115	3	usually	usually	RB
cord-024061-gxv8y146	115	4	result	result	VBP
cord-024061-gxv8y146	115	5	from	from	IN
cord-024061-gxv8y146	115	6	low	low	JJ
cord-024061-gxv8y146	115	7	sequencing	sequencing	NN
cord-024061-gxv8y146	115	8	quality	quality	NN
cord-024061-gxv8y146	115	9	,	,	,
cord-024061-gxv8y146	115	10	alignment	alignment	NN
cord-024061-gxv8y146	115	11	errors	error	NNS
cord-024061-gxv8y146	115	12	,	,	,
cord-024061-gxv8y146	115	13	laboratory	laboratory	NN
cord-024061-gxv8y146	115	14	adopted	adopt	VBN
cord-024061-gxv8y146	115	15	and	and	CC
cord-024061-gxv8y146	115	16	vaccine	vaccine	NN
cord-024061-gxv8y146	115	17	strains	strain	NNS
cord-024061-gxv8y146	115	18	,	,	,
cord-024061-gxv8y146	115	19	as	as	RB
cord-024061-gxv8y146	115	20	well	well	RB
cord-024061-gxv8y146	115	21	as	as	IN
cord-024061-gxv8y146	115	22	natural	natural	JJ
cord-024061-gxv8y146	115	23	biological	biological	JJ
cord-024061-gxv8y146	115	24	processes	process	NNS
cord-024061-gxv8y146	115	25	such	such	JJ
cord-024061-gxv8y146	115	26	as	as	IN
cord-024061-gxv8y146	115	27	recombination	recombination	NN
cord-024061-gxv8y146	115	28	.	.	.
cord-024061-gxv8y146	116	1	Once	once	IN
cord-024061-gxv8y146	116	2	the	the	DT
cord-024061-gxv8y146	116	3	sequence	sequence	NN
cord-024061-gxv8y146	116	4	dataset	dataset	NN
cord-024061-gxv8y146	116	5	and	and	CC
cord-024061-gxv8y146	116	6	their	-PRON-	PRP$
cord-024061-gxv8y146	116	7	metadata	metadata	NN
cord-024061-gxv8y146	116	8	are	be	VBP
cord-024061-gxv8y146	116	9	curated	curate	VBN
cord-024061-gxv8y146	116	10	(	(	-LRB-
cord-024061-gxv8y146	116	11	by	by	IN
cord-024061-gxv8y146	116	12	the	the	DT
cord-024061-gxv8y146	116	13	past	past	JJ
cord-024061-gxv8y146	116	14	two	two	CD
cord-024061-gxv8y146	116	15	steps	step	NNS
cord-024061-gxv8y146	116	16	,	,	,
cord-024061-gxv8y146	116	17	described	describe	VBN
cord-024061-gxv8y146	116	18	above	above	IN
cord-024061-gxv8y146	116	19	)	)	-RRB-
cord-024061-gxv8y146	116	20	,	,	,
cord-024061-gxv8y146	116	21	we	-PRON-	PRP
cord-024061-gxv8y146	116	22	provide	provide	VBP
cord-024061-gxv8y146	116	23	a	a	DT
cord-024061-gxv8y146	116	24	variety	variety	NN
cord-024061-gxv8y146	116	25	of	of	IN
cord-024061-gxv8y146	116	26	choices	choice	NNS
cord-024061-gxv8y146	116	27	for	for	IN
cord-024061-gxv8y146	116	28	selecting	select	VBG
cord-024061-gxv8y146	116	29	and	and	CC
cord-024061-gxv8y146	116	30	running	run	VBG
cord-024061-gxv8y146	116	31	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	116	32	models	model	NNS
cord-024061-gxv8y146	116	33	depending	depend	VBG
cord-024061-gxv8y146	116	34	on	on	IN
cord-024061-gxv8y146	116	35	the	the	DT
cord-024061-gxv8y146	116	36	objectives	objective	NNS
cord-024061-gxv8y146	116	37	of	of	IN
cord-024061-gxv8y146	116	38	the	the	DT
cord-024061-gxv8y146	116	39	study	study	NN
cord-024061-gxv8y146	116	40	.	.	.
cord-024061-gxv8y146	117	1	Steps	step	NNS
cord-024061-gxv8y146	117	2	involving	involve	VBG
cord-024061-gxv8y146	117	3	prior	prior	JJ
cord-024061-gxv8y146	117	4	specification	specification	NN
cord-024061-gxv8y146	117	5	,	,	,
cord-024061-gxv8y146	117	6	simulations	simulation	NNS
cord-024061-gxv8y146	117	7	,	,	,
cord-024061-gxv8y146	117	8	and	and	CC
cord-024061-gxv8y146	117	9	summarizing	summarize	VBG
cord-024061-gxv8y146	117	10	posterior	posterior	JJ
cord-024061-gxv8y146	117	11	inferences	inference	NNS
cord-024061-gxv8y146	117	12	are	be	VBP
cord-024061-gxv8y146	117	13	all	all	DT
cord-024061-gxv8y146	117	14	implemented	implement	VBN
cord-024061-gxv8y146	117	15	in	in	IN
cord-024061-gxv8y146	117	16	the	the	DT
cord-024061-gxv8y146	117	17	BEAST	BEAST	NNP
cord-024061-gxv8y146	117	18	software	software	NN
cord-024061-gxv8y146	117	19	package	package	NN
cord-024061-gxv8y146	117	20	(	(	-LRB-
cord-024061-gxv8y146	117	21	24	24	CD
cord-024061-gxv8y146	117	22	)	)	-RRB-
cord-024061-gxv8y146	117	23	.	.	.
cord-024061-gxv8y146	118	1	Large	large	JJ
cord-024061-gxv8y146	118	2	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	118	3	distances	distance	NNS
cord-024061-gxv8y146	118	4	(	(	-LRB-
cord-024061-gxv8y146	118	5	i.e.	i.e.	FW
cord-024061-gxv8y146	118	6	,	,	,
cord-024061-gxv8y146	118	7	substitution	substitution	NN
cord-024061-gxv8y146	118	8	per	per	IN
cord-024061-gxv8y146	118	9	site	site	NN
cord-024061-gxv8y146	118	10	)	)	-RRB-
cord-024061-gxv8y146	118	11	between	between	IN
cord-024061-gxv8y146	118	12	pairs	pair	NNS
cord-024061-gxv8y146	118	13	of	of	IN
cord-024061-gxv8y146	118	14	sequences	sequence	NNS
cord-024061-gxv8y146	118	15	caused	cause	VBN
cord-024061-gxv8y146	118	16	by	by	IN
cord-024061-gxv8y146	118	17	multiple	multiple	JJ
cord-024061-gxv8y146	118	18	substitution	substitution	NN
cord-024061-gxv8y146	118	19	events	event	NNS
cord-024061-gxv8y146	118	20	through	through	IN
cord-024061-gxv8y146	118	21	time	time	NN
cord-024061-gxv8y146	118	22	can	can	MD
cord-024061-gxv8y146	118	23	be	be	VB
cord-024061-gxv8y146	118	24	underestimated	underestimate	VBN
cord-024061-gxv8y146	118	25	when	when	WRB
cord-024061-gxv8y146	118	26	using	use	VBG
cord-024061-gxv8y146	118	27	simple	simple	JJ
cord-024061-gxv8y146	118	28	distance	distance	NN
cord-024061-gxv8y146	118	29	measures	measure	NNS
cord-024061-gxv8y146	118	30	(	(	-LRB-
cord-024061-gxv8y146	118	31	e.g.	e.g.	RB
cord-024061-gxv8y146	118	32	,	,	,
cord-024061-gxv8y146	118	33	Hamming	Hamming	NNP
cord-024061-gxv8y146	118	34	distance	distance	NN
cord-024061-gxv8y146	118	35	)	)	-RRB-
cord-024061-gxv8y146	118	36	(	(	-LRB-
cord-024061-gxv8y146	118	37	64	64	CD
cord-024061-gxv8y146	118	38	)	)	-RRB-
cord-024061-gxv8y146	118	39	.	.	.
cord-024061-gxv8y146	119	1	Hence	hence	RB
cord-024061-gxv8y146	119	2	,	,	,
cord-024061-gxv8y146	119	3	the	the	DT
cord-024061-gxv8y146	119	4	distance	distance	NN
cord-024061-gxv8y146	119	5	correction	correction	NN
cord-024061-gxv8y146	119	6	technique	technique	NN
cord-024061-gxv8y146	119	7	provided	provide	VBN
cord-024061-gxv8y146	119	8	by	by	IN
cord-024061-gxv8y146	119	9	the	the	DT
cord-024061-gxv8y146	119	10	substitution	substitution	NN
cord-024061-gxv8y146	119	11	models	model	NNS
cord-024061-gxv8y146	119	12	can	can	MD
cord-024061-gxv8y146	119	13	compensate	compensate	VB
cord-024061-gxv8y146	119	14	for	for	IN
cord-024061-gxv8y146	119	15	the	the	DT
cord-024061-gxv8y146	119	16	underestimation	underestimation	NN
cord-024061-gxv8y146	119	17	of	of	IN
cord-024061-gxv8y146	119	18	such	such	JJ
cord-024061-gxv8y146	119	19	large	large	JJ
cord-024061-gxv8y146	119	20	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	119	21	distances	distance	NNS
cord-024061-gxv8y146	119	22	(	(	-LRB-
cord-024061-gxv8y146	119	23	64	64	CD
cord-024061-gxv8y146	119	24	)	)	-RRB-
cord-024061-gxv8y146	119	25	.	.	.
cord-024061-gxv8y146	120	1	Phylogenetic	phylogenetic	JJ
cord-024061-gxv8y146	120	2	tree	tree	NN
cord-024061-gxv8y146	120	3	algorithms	algorithm	NNS
cord-024061-gxv8y146	120	4	such	such	JJ
cord-024061-gxv8y146	120	5	as	as	IN
cord-024061-gxv8y146	120	6	the	the	DT
cord-024061-gxv8y146	120	7	ML	ML	NNP
cord-024061-gxv8y146	120	8	approach	approach	NN
cord-024061-gxv8y146	120	9	incorporates	incorporate	VBZ
cord-024061-gxv8y146	120	10	substitution	substitution	NN
cord-024061-gxv8y146	120	11	models	model	NNS
cord-024061-gxv8y146	120	12	that	that	WDT
cord-024061-gxv8y146	120	13	employs	employ	VBZ
cord-024061-gxv8y146	120	14	continuoustime	continuoustime	NNP
cord-024061-gxv8y146	120	15	Markov	Markov	NNP
cord-024061-gxv8y146	120	16	chain	chain	NN
cord-024061-gxv8y146	120	17	(	(	-LRB-
cord-024061-gxv8y146	120	18	CTMC	CTMC	NNP
cord-024061-gxv8y146	120	19	)	)	-RRB-
cord-024061-gxv8y146	120	20	models	model	NNS
cord-024061-gxv8y146	120	21	(	(	-LRB-
cord-024061-gxv8y146	120	22	52	52	CD
cord-024061-gxv8y146	120	23	)	)	-RRB-
cord-024061-gxv8y146	120	24	.	.	.
cord-024061-gxv8y146	121	1	CTMC	CTMC	NNP
cord-024061-gxv8y146	121	2	models	model	NNS
cord-024061-gxv8y146	121	3	are	be	VBP
cord-024061-gxv8y146	121	4	stochastic	stochastic	JJ
cord-024061-gxv8y146	121	5	methods	method	NNS
cord-024061-gxv8y146	121	6	that	that	WDT
cord-024061-gxv8y146	121	7	take	take	VBP
cord-024061-gxv8y146	121	8	values	value	NNS
cord-024061-gxv8y146	121	9	from	from	IN
cord-024061-gxv8y146	121	10	a	a	DT
cord-024061-gxv8y146	121	11	discrete	discrete	JJ
cord-024061-gxv8y146	121	12	state	state	NN
cord-024061-gxv8y146	121	13	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	121	14	space	space	NN
cord-024061-gxv8y146	121	15	at	at	IN
cord-024061-gxv8y146	121	16	random	random	JJ
cord-024061-gxv8y146	121	17	times	time	NNS
cord-024061-gxv8y146	121	18	,	,	,
cord-024061-gxv8y146	121	19	which	which	WDT
cord-024061-gxv8y146	121	20	is	be	VBZ
cord-024061-gxv8y146	121	21	analogous	analogous	JJ
cord-024061-gxv8y146	121	22	to	to	IN
cord-024061-gxv8y146	121	23	a	a	DT
cord-024061-gxv8y146	121	24	nucleotide	nucleotide	JJ
cord-024061-gxv8y146	121	25	or	or	CC
cord-024061-gxv8y146	121	26	amino	amino	NN
cord-024061-gxv8y146	121	27	acid	acid	NN
cord-024061-gxv8y146	121	28	substitution	substitution	NN
cord-024061-gxv8y146	121	29	process	process	NN
cord-024061-gxv8y146	121	30	,	,	,
cord-024061-gxv8y146	121	31	allowing	allow	VBG
cord-024061-gxv8y146	121	32	for	for	IN
cord-024061-gxv8y146	121	33	glimpsing	glimpse	VBG
cord-024061-gxv8y146	121	34	the	the	DT
cord-024061-gxv8y146	121	35	complete	complete	JJ
cord-024061-gxv8y146	121	36	state	state	NN
cord-024061-gxv8y146	121	37	history	history	NN
cord-024061-gxv8y146	121	38	over	over	IN
cord-024061-gxv8y146	121	39	the	the	DT
cord-024061-gxv8y146	121	40	entire	entire	JJ
cord-024061-gxv8y146	121	41	phylogeny	phylogeny	NN
cord-024061-gxv8y146	121	42	where	where	WRB
cord-024061-gxv8y146	121	43	statistical	statistical	JJ
cord-024061-gxv8y146	121	44	inferences	inference	NNS
cord-024061-gxv8y146	121	45	are	be	VBP
cord-024061-gxv8y146	121	46	drawn	draw	VBN
cord-024061-gxv8y146	121	47	(	(	-LRB-
cord-024061-gxv8y146	121	48	52	52	CD
cord-024061-gxv8y146	121	49	,	,	,
cord-024061-gxv8y146	121	50	64	64	CD
cord-024061-gxv8y146	121	51	,	,	,
cord-024061-gxv8y146	121	52	65	65	CD
cord-024061-gxv8y146	121	53	)	)	-RRB-
cord-024061-gxv8y146	121	54	.	.	.
cord-024061-gxv8y146	122	1	Out	out	IN
cord-024061-gxv8y146	122	2	of	of	IN
cord-024061-gxv8y146	122	3	many	many	JJ
cord-024061-gxv8y146	122	4	available	available	JJ
cord-024061-gxv8y146	122	5	substitution	substitution	NN
cord-024061-gxv8y146	122	6	models	model	NNS
cord-024061-gxv8y146	122	7	,	,	,
cord-024061-gxv8y146	122	8	the	the	DT
cord-024061-gxv8y146	122	9	Hasegawa	Hasegawa	NNP
cord-024061-gxv8y146	122	10	,	,	,
cord-024061-gxv8y146	122	11	Kishino	Kishino	NNP
cord-024061-gxv8y146	122	12	,	,	,
cord-024061-gxv8y146	122	13	and	and	CC
cord-024061-gxv8y146	122	14	Yano	Yano	NNP
cord-024061-gxv8y146	122	15	(	(	-LRB-
cord-024061-gxv8y146	122	16	HKY	HKY	NNP
cord-024061-gxv8y146	122	17	)	)	-RRB-
cord-024061-gxv8y146	122	18	(	(	-LRB-
cord-024061-gxv8y146	122	19	66	66	CD
cord-024061-gxv8y146	122	20	)	)	-RRB-
cord-024061-gxv8y146	122	21	and	and	CC
cord-024061-gxv8y146	122	22	the	the	DT
cord-024061-gxv8y146	122	23	general	general	JJ
cord-024061-gxv8y146	122	24	time	time	NN
cord-024061-gxv8y146	122	25	-	-	HYPH
cord-024061-gxv8y146	122	26	reversable	reversable	JJ
cord-024061-gxv8y146	122	27	(	(	-LRB-
cord-024061-gxv8y146	122	28	GTR	GTR	NNP
cord-024061-gxv8y146	122	29	)	)	-RRB-
cord-024061-gxv8y146	122	30	(	(	-LRB-
cord-024061-gxv8y146	122	31	52	52	CD
cord-024061-gxv8y146	122	32	,	,	,
cord-024061-gxv8y146	122	33	67	67	CD
cord-024061-gxv8y146	122	34	)	)	-RRB-
cord-024061-gxv8y146	122	35	are	be	VBP
cord-024061-gxv8y146	122	36	the	the	DT
cord-024061-gxv8y146	122	37	most	most	RBS
cord-024061-gxv8y146	122	38	common	common	JJ
cord-024061-gxv8y146	122	39	models	model	NNS
cord-024061-gxv8y146	122	40	used	use	VBN
cord-024061-gxv8y146	122	41	to	to	TO
cord-024061-gxv8y146	122	42	infer	infer	VB
cord-024061-gxv8y146	122	43	the	the	DT
cord-024061-gxv8y146	122	44	phylogeny	phylogeny	NN
cord-024061-gxv8y146	122	45	of	of	IN
cord-024061-gxv8y146	122	46	rapidly	rapidly	RB
cord-024061-gxv8y146	122	47	evolving	evolve	VBG
cord-024061-gxv8y146	122	48	pathogens	pathogen	NNS
cord-024061-gxv8y146	122	49	.	.	.
cord-024061-gxv8y146	123	1	Briefly	briefly	RB
cord-024061-gxv8y146	123	2	,	,	,
cord-024061-gxv8y146	123	3	both	both	DT
cord-024061-gxv8y146	123	4	substitution	substitution	NN
cord-024061-gxv8y146	123	5	models	model	NNS
cord-024061-gxv8y146	123	6	assume	assume	VBP
cord-024061-gxv8y146	123	7	a	a	DT
cord-024061-gxv8y146	123	8	constant	constant	JJ
cord-024061-gxv8y146	123	9	rate	rate	NN
cord-024061-gxv8y146	123	10	of	of	IN
cord-024061-gxv8y146	123	11	evolution	evolution	NN
cord-024061-gxv8y146	123	12	and	and	CC
cord-024061-gxv8y146	123	13	have	have	VB
cord-024061-gxv8y146	123	14	two	two	CD
cord-024061-gxv8y146	123	15	major	major	JJ
cord-024061-gxv8y146	123	16	parameters	parameter	NNS
cord-024061-gxv8y146	123	17	,	,	,
cord-024061-gxv8y146	123	18	including	include	VBG
cord-024061-gxv8y146	123	19	a	a	DT
cord-024061-gxv8y146	123	20	rate	rate	NN
cord-024061-gxv8y146	123	21	matrix	matrix	NN
cord-024061-gxv8y146	123	22	(	(	-LRB-
cord-024061-gxv8y146	123	23	Q	Q	NNP
cord-024061-gxv8y146	123	24	)	)	-RRB-
cord-024061-gxv8y146	123	25	and	and	CC
cord-024061-gxv8y146	123	26	an	an	DT
cord-024061-gxv8y146	123	27	equilibrium	equilibrium	NN
cord-024061-gxv8y146	123	28	vector	vector	NN
cord-024061-gxv8y146	123	29	of	of	IN
cord-024061-gxv8y146	123	30	base	base	NN
cord-024061-gxv8y146	123	31	frequencies	frequency	NNS
cord-024061-gxv8y146	123	32	.	.	.
cord-024061-gxv8y146	124	1	However	however	RB
cord-024061-gxv8y146	124	2	,	,	,
cord-024061-gxv8y146	124	3	the	the	DT
cord-024061-gxv8y146	124	4	HKY	HKY	NNP
cord-024061-gxv8y146	124	5	model	model	NN
cord-024061-gxv8y146	124	6	rate	rate	NN
cord-024061-gxv8y146	124	7	matrix	matrix	NN
cord-024061-gxv8y146	124	8	has	have	VBZ
cord-024061-gxv8y146	124	9	two	two	CD
cord-024061-gxv8y146	124	10	exchangeability	exchangeability	NN
cord-024061-gxv8y146	124	11	parameters	parameter	NNS
cord-024061-gxv8y146	124	12	,	,	,
cord-024061-gxv8y146	124	13	including	include	VBG
cord-024061-gxv8y146	124	14	one	one	CD
cord-024061-gxv8y146	124	15	transition	transition	NN
cord-024061-gxv8y146	124	16	rate	rate	NN
cord-024061-gxv8y146	124	17	and	and	CC
cord-024061-gxv8y146	124	18	one	one	CD
cord-024061-gxv8y146	124	19	transversion	transversion	NN
cord-024061-gxv8y146	124	20	rate	rate	NN
cord-024061-gxv8y146	124	21	parameters	parameter	NNS
cord-024061-gxv8y146	124	22	(	(	-LRB-
cord-024061-gxv8y146	124	23	66	66	CD
cord-024061-gxv8y146	124	24	)	)	-RRB-
cord-024061-gxv8y146	124	25	,	,	,
cord-024061-gxv8y146	124	26	while	while	IN
cord-024061-gxv8y146	124	27	the	the	DT
cord-024061-gxv8y146	124	28	GTR	GTR	NNP
cord-024061-gxv8y146	124	29	model	model	NN
cord-024061-gxv8y146	124	30	has	have	VBZ
cord-024061-gxv8y146	124	31	a	a	DT
cord-024061-gxv8y146	124	32	symmetrical	symmetrical	JJ
cord-024061-gxv8y146	124	33	substitution	substitution	NN
cord-024061-gxv8y146	124	34	rate	rate	NN
cord-024061-gxv8y146	124	35	matrix	matrix	NN
cord-024061-gxv8y146	124	36	where	where	WRB
cord-024061-gxv8y146	124	37	all	all	PDT
cord-024061-gxv8y146	124	38	the	the	DT
cord-024061-gxv8y146	124	39	exchangeability	exchangeability	NN
cord-024061-gxv8y146	124	40	parameters	parameter	NNS
cord-024061-gxv8y146	124	41	are	be	VBP
cord-024061-gxv8y146	124	42	free	free	JJ
cord-024061-gxv8y146	124	43	(	(	-LRB-
cord-024061-gxv8y146	124	44	67	67	CD
cord-024061-gxv8y146	124	45	)	)	-RRB-
cord-024061-gxv8y146	124	46	.	.	.
cord-024061-gxv8y146	125	1	Accommodating	accommodate	VBG
cord-024061-gxv8y146	125	2	the	the	DT
cord-024061-gxv8y146	125	3	rate	rate	NN
cord-024061-gxv8y146	125	4	variation	variation	NN
cord-024061-gxv8y146	125	5	across	across	IN
cord-024061-gxv8y146	125	6	sites	site	NNS
cord-024061-gxv8y146	125	7	can	can	MD
cord-024061-gxv8y146	125	8	be	be	VB
cord-024061-gxv8y146	125	9	achieved	achieve	VBN
cord-024061-gxv8y146	125	10	by	by	IN
cord-024061-gxv8y146	125	11	combining	combine	VBG
cord-024061-gxv8y146	125	12	substitution	substitution	NN
cord-024061-gxv8y146	125	13	models	model	NNS
cord-024061-gxv8y146	125	14	with	with	IN
cord-024061-gxv8y146	125	15	site	site	NN
cord-024061-gxv8y146	125	16	models	model	NNS
cord-024061-gxv8y146	125	17	such	such	JJ
cord-024061-gxv8y146	125	18	as	as	IN
cord-024061-gxv8y146	125	19	the	the	DT
cord-024061-gxv8y146	125	20	discrete	discrete	JJ
cord-024061-gxv8y146	125	21	gamma	gamma	NN
cord-024061-gxv8y146	125	22	(	(	-LRB-
cord-024061-gxv8y146	125	23	Ŵ	ŵ	CD
cord-024061-gxv8y146	125	24	)	)	-RRB-
cord-024061-gxv8y146	125	25	model	model	NN
cord-024061-gxv8y146	125	26	(	(	-LRB-
cord-024061-gxv8y146	125	27	68	68	CD
cord-024061-gxv8y146	125	28	)	)	-RRB-
cord-024061-gxv8y146	125	29	.	.	.
cord-024061-gxv8y146	126	1	However	however	RB
cord-024061-gxv8y146	126	2	,	,	,
cord-024061-gxv8y146	126	3	when	when	WRB
cord-024061-gxv8y146	126	4	assuming	assume	VBG
cord-024061-gxv8y146	126	5	that	that	IN
cord-024061-gxv8y146	126	6	the	the	DT
cord-024061-gxv8y146	126	7	evolution	evolution	NN
cord-024061-gxv8y146	126	8	rate	rate	NN
cord-024061-gxv8y146	126	9	is	be	VBZ
cord-024061-gxv8y146	126	10	equal	equal	JJ
cord-024061-gxv8y146	126	11	to	to	IN
cord-024061-gxv8y146	126	12	zero	zero	CD
cord-024061-gxv8y146	126	13	,	,	,
cord-024061-gxv8y146	126	14	the	the	DT
cord-024061-gxv8y146	126	15	invariant	invariant	JJ
cord-024061-gxv8y146	126	16	site	site	NN
cord-024061-gxv8y146	126	17	(	(	-LRB-
cord-024061-gxv8y146	126	18	I	i	NN
cord-024061-gxv8y146	126	19	)	)	-RRB-
cord-024061-gxv8y146	126	20	model	model	NN
cord-024061-gxv8y146	126	21	is	be	VBZ
cord-024061-gxv8y146	126	22	combined	combine	VBN
cord-024061-gxv8y146	126	23	with	with	IN
cord-024061-gxv8y146	126	24	the	the	DT
cord-024061-gxv8y146	126	25	corresponding	corresponding	JJ
cord-024061-gxv8y146	126	26	substitution	substitution	NN
cord-024061-gxv8y146	126	27	model	model	NN
cord-024061-gxv8y146	126	28	(	(	-LRB-
cord-024061-gxv8y146	126	29	69	69	CD
cord-024061-gxv8y146	126	30	)	)	-RRB-
cord-024061-gxv8y146	126	31	.	.	.
cord-024061-gxv8y146	127	1	Selection	selection	NN
cord-024061-gxv8y146	127	2	pressure	pressure	NN
cord-024061-gxv8y146	127	3	in	in	IN
cord-024061-gxv8y146	127	4	protein	protein	NN
cord-024061-gxv8y146	127	5	-	-	HYPH
cord-024061-gxv8y146	127	6	coding	code	VBG
cord-024061-gxv8y146	127	7	genes	gene	NNS
cord-024061-gxv8y146	127	8	of	of	IN
cord-024061-gxv8y146	127	9	rapidly	rapidly	RB
cord-024061-gxv8y146	127	10	evolving	evolve	VBG
cord-024061-gxv8y146	127	11	pathogens	pathogen	NNS
cord-024061-gxv8y146	127	12	,	,	,
cord-024061-gxv8y146	127	13	in	in	IN
cord-024061-gxv8y146	127	14	terms	term	NNS
cord-024061-gxv8y146	127	15	of	of	IN
cord-024061-gxv8y146	127	16	synonymous	synonymous	JJ
cord-024061-gxv8y146	127	17	to	to	IN
cord-024061-gxv8y146	127	18	nonsynonymous	nonsynonymous	JJ
cord-024061-gxv8y146	127	19	substitutions	substitution	NNS
cord-024061-gxv8y146	127	20	,	,	,
cord-024061-gxv8y146	127	21	usually	usually	RB
cord-024061-gxv8y146	127	22	occurs	occur	VBZ
cord-024061-gxv8y146	127	23	at	at	IN
cord-024061-gxv8y146	127	24	high	high	JJ
cord-024061-gxv8y146	127	25	rates	rate	NNS
cord-024061-gxv8y146	127	26	(	(	-LRB-
cord-024061-gxv8y146	127	27	70	70	CD
cord-024061-gxv8y146	127	28	)	)	-RRB-
cord-024061-gxv8y146	127	29	.	.	.
cord-024061-gxv8y146	128	1	This	this	DT
cord-024061-gxv8y146	128	2	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	128	3	phenomenon	phenomenon	NN
cord-024061-gxv8y146	128	4	can	can	MD
cord-024061-gxv8y146	128	5	affect	affect	VB
cord-024061-gxv8y146	128	6	estimates	estimate	NNS
cord-024061-gxv8y146	128	7	of	of	IN
cord-024061-gxv8y146	128	8	divergence	divergence	NN
cord-024061-gxv8y146	128	9	time	time	NN
cord-024061-gxv8y146	128	10	and	and	CC
cord-024061-gxv8y146	128	11	,	,	,
cord-024061-gxv8y146	128	12	therefore	therefore	RB
cord-024061-gxv8y146	128	13	,	,	,
cord-024061-gxv8y146	128	14	need	need	VBP
cord-024061-gxv8y146	128	15	to	to	TO
cord-024061-gxv8y146	128	16	be	be	VB
cord-024061-gxv8y146	128	17	accounted	account	VBN
cord-024061-gxv8y146	128	18	for	for	IN
cord-024061-gxv8y146	128	19	when	when	WRB
cord-024061-gxv8y146	128	20	selecting	select	VBG
cord-024061-gxv8y146	128	21	a	a	DT
cord-024061-gxv8y146	128	22	substitution	substitution	NN
cord-024061-gxv8y146	128	23	model	model	NN
cord-024061-gxv8y146	128	24	(	(	-LRB-
cord-024061-gxv8y146	128	25	71	71	CD
cord-024061-gxv8y146	128	26	)	)	-RRB-
cord-024061-gxv8y146	128	27	.	.	.
cord-024061-gxv8y146	129	1	Partitioning	partition	VBG
cord-024061-gxv8y146	129	2	the	the	DT
cord-024061-gxv8y146	129	3	gene	gene	NN
cord-024061-gxv8y146	129	4	segment	segment	NN
cord-024061-gxv8y146	129	5	into	into	IN
cord-024061-gxv8y146	129	6	unique	unique	JJ
cord-024061-gxv8y146	129	7	codon	codon	NN
cord-024061-gxv8y146	129	8	positions	position	NNS
cord-024061-gxv8y146	129	9	and	and	CC
cord-024061-gxv8y146	129	10	assigning	assign	VBG
cord-024061-gxv8y146	129	11	different	different	JJ
cord-024061-gxv8y146	129	12	substitution	substitution	NN
cord-024061-gxv8y146	129	13	and	and	CC
cord-024061-gxv8y146	129	14	site	site	NN
cord-024061-gxv8y146	129	15	model	model	NN
cord-024061-gxv8y146	129	16	combinations	combination	NNS
cord-024061-gxv8y146	129	17	can	can	MD
cord-024061-gxv8y146	129	18	accommodate	accommodate	VB
cord-024061-gxv8y146	129	19	the	the	DT
cord-024061-gxv8y146	129	20	differences	difference	NNS
cord-024061-gxv8y146	129	21	in	in	IN
cord-024061-gxv8y146	129	22	the	the	DT
cord-024061-gxv8y146	129	23	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	129	24	dynamics	dynamic	NNS
cord-024061-gxv8y146	129	25	within	within	IN
cord-024061-gxv8y146	129	26	gene	gene	NN
cord-024061-gxv8y146	129	27	segments	segment	NNS
cord-024061-gxv8y146	129	28	of	of	IN
cord-024061-gxv8y146	129	29	the	the	DT
cord-024061-gxv8y146	129	30	pathogen	pathogen	NN
cord-024061-gxv8y146	129	31	under	under	IN
cord-024061-gxv8y146	129	32	study	study	NN
cord-024061-gxv8y146	129	33	(	(	-LRB-
cord-024061-gxv8y146	129	34	70	70	CD
cord-024061-gxv8y146	129	35	,	,	,
cord-024061-gxv8y146	129	36	72	72	CD
cord-024061-gxv8y146	129	37	)	)	-RRB-
cord-024061-gxv8y146	129	38	.	.	.
cord-024061-gxv8y146	130	1	Different	different	JJ
cord-024061-gxv8y146	130	2	substitution	substitution	NN
cord-024061-gxv8y146	130	3	,	,	,
cord-024061-gxv8y146	130	4	sites	site	NNS
cord-024061-gxv8y146	130	5	,	,	,
cord-024061-gxv8y146	130	6	and	and	CC
cord-024061-gxv8y146	130	7	codon	codon	NN
cord-024061-gxv8y146	130	8	partitioning	partitioning	NN
cord-024061-gxv8y146	130	9	models	model	NNS
cord-024061-gxv8y146	130	10	are	be	VBP
cord-024061-gxv8y146	130	11	implemented	implement	VBN
cord-024061-gxv8y146	130	12	in	in	IN
cord-024061-gxv8y146	130	13	many	many	JJ
cord-024061-gxv8y146	130	14	ML	ml	NN
cord-024061-gxv8y146	130	15	software	software	NN
cord-024061-gxv8y146	130	16	packages	package	NNS
cord-024061-gxv8y146	130	17	as	as	RB
cord-024061-gxv8y146	130	18	well	well	RB
cord-024061-gxv8y146	130	19	as	as	IN
cord-024061-gxv8y146	130	20	in	in	IN
cord-024061-gxv8y146	130	21	BEAST	BEAST	NNP
cord-024061-gxv8y146	130	22	.	.	.
cord-024061-gxv8y146	131	1	However	however	RB
cord-024061-gxv8y146	131	2	,	,	,
cord-024061-gxv8y146	131	3	selecting	select	VBG
cord-024061-gxv8y146	131	4	the	the	DT
cord-024061-gxv8y146	131	5	most	most	RBS
cord-024061-gxv8y146	131	6	realistic	realistic	JJ
cord-024061-gxv8y146	131	7	substitution	substitution	NN
cord-024061-gxv8y146	131	8	/	/	SYM
cord-024061-gxv8y146	131	9	site	site	NN
cord-024061-gxv8y146	131	10	model	model	NN
cord-024061-gxv8y146	131	11	and	and	CC
cord-024061-gxv8y146	131	12	partitioning	partitioning	NN
cord-024061-gxv8y146	131	13	scheme	scheme	NN
cord-024061-gxv8y146	131	14	for	for	IN
cord-024061-gxv8y146	131	15	the	the	DT
cord-024061-gxv8y146	131	16	sequence	sequence	NN
cord-024061-gxv8y146	131	17	data	data	NN
cord-024061-gxv8y146	131	18	can	can	MD
cord-024061-gxv8y146	131	19	be	be	VB
cord-024061-gxv8y146	131	20	statistically	statistically	RB
cord-024061-gxv8y146	131	21	achieved	achieve	VBN
cord-024061-gxv8y146	131	22	using	use	VBG
cord-024061-gxv8y146	131	23	either	either	CC
cord-024061-gxv8y146	131	24	Bayesian	Bayesian	NNP
cord-024061-gxv8y146	131	25	Information	Information	NNP
cord-024061-gxv8y146	131	26	Criterion	Criterion	NNP
cord-024061-gxv8y146	131	27	(	(	-LRB-
cord-024061-gxv8y146	131	28	BIC	BIC	NNP
cord-024061-gxv8y146	131	29	)	)	-RRB-
cord-024061-gxv8y146	131	30	(	(	-LRB-
cord-024061-gxv8y146	131	31	73	73	CD
cord-024061-gxv8y146	131	32	)	)	-RRB-
cord-024061-gxv8y146	131	33	,	,	,
cord-024061-gxv8y146	131	34	Akaike	Akaike	NNP
cord-024061-gxv8y146	131	35	Information	Information	NNP
cord-024061-gxv8y146	131	36	Criterion	Criterion	NNP
cord-024061-gxv8y146	131	37	(	(	-LRB-
cord-024061-gxv8y146	131	38	AIC	AIC	NNP
cord-024061-gxv8y146	131	39	)	)	-RRB-
cord-024061-gxv8y146	131	40	,	,	,
cord-024061-gxv8y146	131	41	or	or	CC
cord-024061-gxv8y146	131	42	the	the	DT
cord-024061-gxv8y146	131	43	corrected	correct	VBN
cord-024061-gxv8y146	131	44	Akaike	Akaike	NNP
cord-024061-gxv8y146	131	45	Information	Information	NNP
cord-024061-gxv8y146	131	46	Criterion	Criterion	NNP
cord-024061-gxv8y146	131	47	(	(	-LRB-
cord-024061-gxv8y146	131	48	AICc	AICc	NNP
cord-024061-gxv8y146	131	49	)	)	-RRB-
cord-024061-gxv8y146	131	50	(	(	-LRB-
cord-024061-gxv8y146	131	51	74	74	CD
cord-024061-gxv8y146	131	52	,	,	,
cord-024061-gxv8y146	131	53	75	75	CD
cord-024061-gxv8y146	131	54	)	)	-RRB-
cord-024061-gxv8y146	131	55	.	.	.
cord-024061-gxv8y146	132	1	These	these	DT
cord-024061-gxv8y146	132	2	ML	ML	NNP
cord-024061-gxv8y146	132	3	-	-	HYPH
cord-024061-gxv8y146	132	4	based	base	VBN
cord-024061-gxv8y146	132	5	statistical	statistical	JJ
cord-024061-gxv8y146	132	6	methods	method	NNS
cord-024061-gxv8y146	132	7	are	be	VBP
cord-024061-gxv8y146	132	8	wellimplemented	wellimplemente	VBN
cord-024061-gxv8y146	132	9	in	in	IN
cord-024061-gxv8y146	132	10	both	both	DT
cord-024061-gxv8y146	132	11	PartitionFinder	PartitionFinder	NNP
cord-024061-gxv8y146	132	12	(	(	-LRB-
cord-024061-gxv8y146	132	13	76	76	CD
cord-024061-gxv8y146	132	14	)	)	-RRB-
cord-024061-gxv8y146	132	15	and	and	CC
cord-024061-gxv8y146	132	16	jModelTest	jModelTest	NNP
cord-024061-gxv8y146	132	17	(	(	-LRB-
cord-024061-gxv8y146	132	18	77	77	CD
cord-024061-gxv8y146	132	19	)	)	-RRB-
cord-024061-gxv8y146	132	20	.	.	.
cord-024061-gxv8y146	133	1	Yet	yet	RB
cord-024061-gxv8y146	133	2	,	,	,
cord-024061-gxv8y146	133	3	a	a	DT
cord-024061-gxv8y146	133	4	more	more	RBR
cord-024061-gxv8y146	133	5	robust	robust	JJ
cord-024061-gxv8y146	133	6	Bayesian	bayesian	JJ
cord-024061-gxv8y146	133	7	method	method	NN
cord-024061-gxv8y146	133	8	for	for	IN
cord-024061-gxv8y146	133	9	selecting	select	VBG
cord-024061-gxv8y146	133	10	a	a	DT
cord-024061-gxv8y146	133	11	site	site	NN
cord-024061-gxv8y146	133	12	model	model	NN
cord-024061-gxv8y146	133	13	and	and	CC
cord-024061-gxv8y146	133	14	an	an	DT
cord-024061-gxv8y146	133	15	associated	associate	VBN
cord-024061-gxv8y146	133	16	substitution	substitution	NN
cord-024061-gxv8y146	133	17	model	model	NN
cord-024061-gxv8y146	133	18	is	be	VBZ
cord-024061-gxv8y146	133	19	implemented	implement	VBN
cord-024061-gxv8y146	133	20	as	as	IN
cord-024061-gxv8y146	133	21	an	an	DT
cord-024061-gxv8y146	133	22	add	add	VB
cord-024061-gxv8y146	133	23	-	-	HYPH
cord-024061-gxv8y146	133	24	on	on	RP
cord-024061-gxv8y146	133	25	package	package	NN
cord-024061-gxv8y146	133	26	in	in	IN
cord-024061-gxv8y146	133	27	BEAST	BEAST	NNP
cord-024061-gxv8y146	133	28	2.X	2.x	CD
cord-024061-gxv8y146	133	29	(	(	-LRB-
cord-024061-gxv8y146	133	30	78	78	CD
cord-024061-gxv8y146	133	31	)	)	-RRB-
cord-024061-gxv8y146	133	32	.	.	.
cord-024061-gxv8y146	134	1	Time	time	NN
cord-024061-gxv8y146	134	2	-	-	HYPH
cord-024061-gxv8y146	134	3	calibrated	calibrate	VBN
cord-024061-gxv8y146	134	4	trees	tree	NNS
cord-024061-gxv8y146	134	5	are	be	VBP
cord-024061-gxv8y146	134	6	modeled	model	VBN
cord-024061-gxv8y146	134	7	with	with	IN
cord-024061-gxv8y146	134	8	the	the	DT
cord-024061-gxv8y146	134	9	genetic	genetic	JJ
cord-024061-gxv8y146	134	10	differences	difference	NNS
cord-024061-gxv8y146	134	11	between	between	IN
cord-024061-gxv8y146	134	12	sequences	sequence	NNS
cord-024061-gxv8y146	134	13	through	through	IN
cord-024061-gxv8y146	134	14	the	the	DT
cord-024061-gxv8y146	134	15	molecular	molecular	JJ
cord-024061-gxv8y146	134	16	clock	clock	NN
cord-024061-gxv8y146	134	17	models	model	NNS
cord-024061-gxv8y146	134	18	,	,	,
cord-024061-gxv8y146	134	19	which	which	WDT
cord-024061-gxv8y146	134	20	is	be	VBZ
cord-024061-gxv8y146	134	21	defined	define	VBN
cord-024061-gxv8y146	134	22	as	as	IN
cord-024061-gxv8y146	134	23	the	the	DT
cord-024061-gxv8y146	134	24	clock	clock	NN
cord-024061-gxv8y146	134	25	that	that	WDT
cord-024061-gxv8y146	134	26	occurs	occur	VBZ
cord-024061-gxv8y146	134	27	after	after	IN
cord-024061-gxv8y146	134	28	a	a	DT
cord-024061-gxv8y146	134	29	stochastic	stochastic	JJ
cord-024061-gxv8y146	134	30	waiting	waiting	NN
cord-024061-gxv8y146	134	31	time	time	NN
cord-024061-gxv8y146	134	32	in	in	IN
cord-024061-gxv8y146	134	33	the	the	DT
cord-024061-gxv8y146	134	34	context	context	NN
cord-024061-gxv8y146	134	35	of	of	IN
cord-024061-gxv8y146	134	36	substitution	substitution	NN
cord-024061-gxv8y146	134	37	rate	rate	NN
cord-024061-gxv8y146	134	38	(	(	-LRB-
cord-024061-gxv8y146	134	39	79	79	CD
cord-024061-gxv8y146	134	40	)	)	-RRB-
cord-024061-gxv8y146	134	41	.	.	.
cord-024061-gxv8y146	135	1	When	when	WRB
cord-024061-gxv8y146	135	2	assuming	assume	VBG
cord-024061-gxv8y146	135	3	that	that	IN
cord-024061-gxv8y146	135	4	the	the	DT
cord-024061-gxv8y146	135	5	substitution	substitution	NN
cord-024061-gxv8y146	135	6	rate	rate	NN
cord-024061-gxv8y146	135	7	across	across	IN
cord-024061-gxv8y146	135	8	the	the	DT
cord-024061-gxv8y146	135	9	branches	branch	NNS
cord-024061-gxv8y146	135	10	is	be	VBZ
cord-024061-gxv8y146	135	11	uniform	uniform	JJ
cord-024061-gxv8y146	135	12	over	over	IN
cord-024061-gxv8y146	135	13	the	the	DT
cord-024061-gxv8y146	135	14	entire	entire	JJ
cord-024061-gxv8y146	135	15	tree	tree	NN
cord-024061-gxv8y146	135	16	,	,	,
cord-024061-gxv8y146	135	17	then	then	RB
cord-024061-gxv8y146	135	18	the	the	DT
cord-024061-gxv8y146	135	19	molecular	molecular	JJ
cord-024061-gxv8y146	135	20	clock	clock	NN
cord-024061-gxv8y146	135	21	model	model	NN
cord-024061-gxv8y146	135	22	is	be	VBZ
cord-024061-gxv8y146	135	23	defined	define	VBN
cord-024061-gxv8y146	135	24	as	as	IN
cord-024061-gxv8y146	135	25	strict	strict	JJ
cord-024061-gxv8y146	135	26	.	.	.
cord-024061-gxv8y146	136	1	However	however	RB
cord-024061-gxv8y146	136	2	,	,	,
cord-024061-gxv8y146	136	3	changes	change	NNS
cord-024061-gxv8y146	136	4	in	in	IN
cord-024061-gxv8y146	136	5	the	the	DT
cord-024061-gxv8y146	136	6	rate	rate	NN
cord-024061-gxv8y146	136	7	of	of	IN
cord-024061-gxv8y146	136	8	evolution	evolution	NN
cord-024061-gxv8y146	136	9	of	of	IN
cord-024061-gxv8y146	136	10	rapidly	rapidly	RB
cord-024061-gxv8y146	136	11	evolving	evolve	VBG
cord-024061-gxv8y146	136	12	pathogens	pathogen	NNS
cord-024061-gxv8y146	136	13	usually	usually	RB
cord-024061-gxv8y146	136	14	differ	differ	VBP
cord-024061-gxv8y146	136	15	between	between	IN
cord-024061-gxv8y146	136	16	the	the	DT
cord-024061-gxv8y146	136	17	subtrees	subtree	NNS
cord-024061-gxv8y146	136	18	of	of	IN
cord-024061-gxv8y146	136	19	its	-PRON-	PRP$
cord-024061-gxv8y146	136	20	inferred	infer	VBN
cord-024061-gxv8y146	136	21	phylogeny	phylogeny	NN
cord-024061-gxv8y146	136	22	,	,	,
cord-024061-gxv8y146	136	23	and	and	CC
cord-024061-gxv8y146	136	24	therefore	therefore	RB
cord-024061-gxv8y146	136	25	,	,	,
cord-024061-gxv8y146	136	26	relaxed	relaxed	JJ
cord-024061-gxv8y146	136	27	branch	branch	NN
cord-024061-gxv8y146	136	28	-	-	HYPH
cord-024061-gxv8y146	136	29	rate	rate	NN
cord-024061-gxv8y146	136	30	models	model	NNS
cord-024061-gxv8y146	136	31	account	account	VBP
cord-024061-gxv8y146	136	32	for	for	IN
cord-024061-gxv8y146	136	33	the	the	DT
cord-024061-gxv8y146	136	34	variation	variation	NN
cord-024061-gxv8y146	136	35	in	in	IN
cord-024061-gxv8y146	136	36	the	the	DT
cord-024061-gxv8y146	136	37	rate	rate	NN
cord-024061-gxv8y146	136	38	of	of	IN
cord-024061-gxv8y146	136	39	molecular	molecular	JJ
cord-024061-gxv8y146	136	40	evolution	evolution	NN
cord-024061-gxv8y146	136	41	from	from	IN
cord-024061-gxv8y146	136	42	clade	clade	NN
cord-024061-gxv8y146	136	43	to	to	IN
cord-024061-gxv8y146	136	44	clade	clade	NN
cord-024061-gxv8y146	136	45	across	across	IN
cord-024061-gxv8y146	136	46	the	the	DT
cord-024061-gxv8y146	136	47	branches	branch	NNS
cord-024061-gxv8y146	136	48	of	of	IN
cord-024061-gxv8y146	136	49	the	the	DT
cord-024061-gxv8y146	136	50	tree	tree	NN
cord-024061-gxv8y146	136	51	(	(	-LRB-
cord-024061-gxv8y146	136	52	79	79	CD
cord-024061-gxv8y146	136	53	)	)	-RRB-
cord-024061-gxv8y146	136	54	.	.	.
cord-024061-gxv8y146	137	1	Substitution	substitution	NN
cord-024061-gxv8y146	137	2	rates	rate	NNS
cord-024061-gxv8y146	137	3	across	across	IN
cord-024061-gxv8y146	137	4	branches	branch	NNS
cord-024061-gxv8y146	137	5	are	be	VBP
cord-024061-gxv8y146	137	6	assumed	assume	VBN
cord-024061-gxv8y146	137	7	to	to	TO
cord-024061-gxv8y146	137	8	be	be	VB
cord-024061-gxv8y146	137	9	either	either	CC
cord-024061-gxv8y146	137	10	autocorrelated	autocorrelate	VBN
cord-024061-gxv8y146	137	11	(	(	-LRB-
cord-024061-gxv8y146	137	12	80	80	CD
cord-024061-gxv8y146	137	13	)	)	-RRB-
cord-024061-gxv8y146	137	14	(	(	-LRB-
cord-024061-gxv8y146	137	15	i.e.	i.e.	FW
cord-024061-gxv8y146	137	16	,	,	,
cord-024061-gxv8y146	137	17	substitution	substitution	NN
cord-024061-gxv8y146	137	18	rates	rate	NNS
cord-024061-gxv8y146	137	19	are	be	VBP
cord-024061-gxv8y146	137	20	dependent	dependent	JJ
cord-024061-gxv8y146	137	21	)	)	-RRB-
cord-024061-gxv8y146	137	22	or	or	CC
cord-024061-gxv8y146	137	23	uncorrelated	uncorrelated	JJ
cord-024061-gxv8y146	137	24	(	(	-LRB-
cord-024061-gxv8y146	137	25	81	81	CD
cord-024061-gxv8y146	137	26	)	)	-RRB-
cord-024061-gxv8y146	137	27	(	(	-LRB-
cord-024061-gxv8y146	137	28	i.e.	i.e.	FW
cord-024061-gxv8y146	137	29	,	,	,
cord-024061-gxv8y146	137	30	substitution	substitution	NN
cord-024061-gxv8y146	137	31	rates	rate	NNS
cord-024061-gxv8y146	137	32	are	be	VBP
cord-024061-gxv8y146	137	33	independent	independent	JJ
cord-024061-gxv8y146	137	34	)	)	-RRB-
cord-024061-gxv8y146	137	35	.	.	.
cord-024061-gxv8y146	138	1	The	the	DT
cord-024061-gxv8y146	138	2	uncorrelated	uncorrelated	JJ
cord-024061-gxv8y146	138	3	branch	branch	NN
cord-024061-gxv8y146	138	4	-	-	HYPH
cord-024061-gxv8y146	138	5	rate	rate	NN
cord-024061-gxv8y146	138	6	prior	prior	RB
cord-024061-gxv8y146	138	7	commonly	commonly	RB
cord-024061-gxv8y146	138	8	used	use	VBN
cord-024061-gxv8y146	138	9	for	for	IN
cord-024061-gxv8y146	138	10	rapidly	rapidly	RB
cord-024061-gxv8y146	138	11	evolving	evolve	VBG
cord-024061-gxv8y146	138	12	viruses	virus	NNS
cord-024061-gxv8y146	138	13	,	,	,
cord-024061-gxv8y146	138	14	in	in	IN
cord-024061-gxv8y146	138	15	which	which	WDT
cord-024061-gxv8y146	138	16	the	the	DT
cord-024061-gxv8y146	138	17	branch	branch	NN
cord-024061-gxv8y146	138	18	rates	rate	NNS
cord-024061-gxv8y146	138	19	are	be	VBP
cord-024061-gxv8y146	138	20	drawn	draw	VBN
cord-024061-gxv8y146	138	21	either	either	CC
cord-024061-gxv8y146	138	22	from	from	IN
cord-024061-gxv8y146	138	23	exponential	exponential	JJ
cord-024061-gxv8y146	138	24	or	or	CC
cord-024061-gxv8y146	138	25	log	log	NN
cord-024061-gxv8y146	138	26	-	-	HYPH
cord-024061-gxv8y146	138	27	normal	normal	JJ
cord-024061-gxv8y146	138	28	parent	parent	NN
cord-024061-gxv8y146	138	29	distribution	distribution	NN
cord-024061-gxv8y146	138	30	(	(	-LRB-
cord-024061-gxv8y146	138	31	81	81	CD
cord-024061-gxv8y146	138	32	)	)	-RRB-
cord-024061-gxv8y146	138	33	.	.	.
cord-024061-gxv8y146	139	1	Another	another	DT
cord-024061-gxv8y146	139	2	alternative	alternative	NN
cord-024061-gxv8y146	139	3	to	to	IN
cord-024061-gxv8y146	139	4	the	the	DT
cord-024061-gxv8y146	139	5	strict	strict	JJ
cord-024061-gxv8y146	139	6	clock	clock	NN
cord-024061-gxv8y146	139	7	model	model	NN
cord-024061-gxv8y146	139	8	is	be	VBZ
cord-024061-gxv8y146	139	9	local	local	JJ
cord-024061-gxv8y146	139	10	molecular	molecular	JJ
cord-024061-gxv8y146	139	11	clocks	clock	NNS
cord-024061-gxv8y146	139	12	,	,	,
cord-024061-gxv8y146	139	13	which	which	WDT
cord-024061-gxv8y146	139	14	can	can	MD
cord-024061-gxv8y146	139	15	estimate	estimate	VB
cord-024061-gxv8y146	139	16	different	different	JJ
cord-024061-gxv8y146	139	17	rates	rate	NNS
cord-024061-gxv8y146	139	18	for	for	IN
cord-024061-gxv8y146	139	19	different	different	JJ
cord-024061-gxv8y146	139	20	predefined	predefined	JJ
cord-024061-gxv8y146	139	21	branch	branch	NN
cord-024061-gxv8y146	139	22	groups	group	NNS
cord-024061-gxv8y146	139	23	within	within	IN
cord-024061-gxv8y146	139	24	a	a	DT
cord-024061-gxv8y146	139	25	tree	tree	NN
cord-024061-gxv8y146	139	26	(	(	-LRB-
cord-024061-gxv8y146	139	27	82	82	CD
cord-024061-gxv8y146	139	28	)	)	-RRB-
cord-024061-gxv8y146	139	29	.	.	.
cord-024061-gxv8y146	140	1	However	however	RB
cord-024061-gxv8y146	140	2	,	,	,
cord-024061-gxv8y146	140	3	for	for	IN
cord-024061-gxv8y146	140	4	large	large	JJ
cord-024061-gxv8y146	140	5	datasets	dataset	NNS
cord-024061-gxv8y146	140	6	,	,	,
cord-024061-gxv8y146	140	7	the	the	DT
cord-024061-gxv8y146	140	8	manual	manual	JJ
cord-024061-gxv8y146	140	9	task	task	NN
cord-024061-gxv8y146	140	10	of	of	IN
cord-024061-gxv8y146	140	11	assigning	assign	VBG
cord-024061-gxv8y146	140	12	branches	branch	NNS
cord-024061-gxv8y146	140	13	to	to	IN
cord-024061-gxv8y146	140	14	different	different	JJ
cord-024061-gxv8y146	140	15	groups	group	NNS
cord-024061-gxv8y146	140	16	is	be	VBZ
cord-024061-gxv8y146	140	17	impractical	impractical	JJ
cord-024061-gxv8y146	140	18	(	(	-LRB-
cord-024061-gxv8y146	140	19	81	81	CD
cord-024061-gxv8y146	140	20	)	)	-RRB-
cord-024061-gxv8y146	140	21	,	,	,
cord-024061-gxv8y146	140	22	and	and	CC
cord-024061-gxv8y146	140	23	therefore	therefore	RB
cord-024061-gxv8y146	140	24	,	,	,
cord-024061-gxv8y146	140	25	Bayesian	Bayesian	NNP
cord-024061-gxv8y146	140	26	random	random	JJ
cord-024061-gxv8y146	140	27	local	local	JJ
cord-024061-gxv8y146	140	28	clocks	clock	NNS
cord-024061-gxv8y146	140	29	can	can	MD
cord-024061-gxv8y146	140	30	nest	nest	VB
cord-024061-gxv8y146	140	31	a	a	DT
cord-024061-gxv8y146	140	32	series	series	NN
cord-024061-gxv8y146	140	33	of	of	IN
cord-024061-gxv8y146	140	34	local	local	JJ
cord-024061-gxv8y146	140	35	clocks	clock	NNS
cord-024061-gxv8y146	140	36	with	with	IN
cord-024061-gxv8y146	140	37	each	each	DT
cord-024061-gxv8y146	140	38	extending	extend	VBG
cord-024061-gxv8y146	140	39	over	over	IN
cord-024061-gxv8y146	140	40	a	a	DT
cord-024061-gxv8y146	140	41	group	group	NN
cord-024061-gxv8y146	140	42	of	of	IN
cord-024061-gxv8y146	140	43	branches	branch	NNS
cord-024061-gxv8y146	140	44	within	within	IN
cord-024061-gxv8y146	140	45	the	the	DT
cord-024061-gxv8y146	140	46	full	full	JJ
cord-024061-gxv8y146	140	47	phylogeny	phylogeny	NN
cord-024061-gxv8y146	140	48	(	(	-LRB-
cord-024061-gxv8y146	140	49	83	83	CD
cord-024061-gxv8y146	140	50	)	)	-RRB-
cord-024061-gxv8y146	140	51	.	.	.
cord-024061-gxv8y146	141	1	Phylogenetic	phylogenetic	JJ
cord-024061-gxv8y146	141	2	trees	tree	NNS
cord-024061-gxv8y146	141	3	are	be	VBP
cord-024061-gxv8y146	141	4	inferred	infer	VBN
cord-024061-gxv8y146	141	5	from	from	IN
cord-024061-gxv8y146	141	6	individually	individually	RB
cord-024061-gxv8y146	141	7	sampled	sample	VBN
cord-024061-gxv8y146	141	8	sequences	sequence	NNS
cord-024061-gxv8y146	141	9	to	to	TO
cord-024061-gxv8y146	141	10	estimate	estimate	VB
cord-024061-gxv8y146	141	11	the	the	DT
cord-024061-gxv8y146	141	12	statistical	statistical	JJ
cord-024061-gxv8y146	141	13	properties	property	NNS
cord-024061-gxv8y146	141	14	of	of	IN
cord-024061-gxv8y146	141	15	the	the	DT
cord-024061-gxv8y146	141	16	population	population	NN
cord-024061-gxv8y146	141	17	where	where	WRB
cord-024061-gxv8y146	141	18	the	the	DT
cord-024061-gxv8y146	141	19	sequences	sequence	NNS
cord-024061-gxv8y146	141	20	were	be	VBD
cord-024061-gxv8y146	141	21	collected	collect	VBN
cord-024061-gxv8y146	141	22	(	(	-LRB-
cord-024061-gxv8y146	141	23	84	84	CD
cord-024061-gxv8y146	141	24	)	)	-RRB-
cord-024061-gxv8y146	141	25	.	.	.
cord-024061-gxv8y146	142	1	Kingman	Kingman	NNP
cord-024061-gxv8y146	142	2	's	's	POS
cord-024061-gxv8y146	142	3	n	n	JJ
cord-024061-gxv8y146	142	4	-	-	HYPH
cord-024061-gxv8y146	142	5	coalescent	coalescent	JJ
cord-024061-gxv8y146	142	6	theory	theory	NN
cord-024061-gxv8y146	142	7	(	(	-LRB-
cord-024061-gxv8y146	142	8	i.e.	i.e.	FW
cord-024061-gxv8y146	142	9	,	,	,
cord-024061-gxv8y146	142	10	node	node	NN
cord-024061-gxv8y146	142	11	-	-	HYPH
cord-024061-gxv8y146	142	12	age	age	NN
cord-024061-gxv8y146	142	13	model	model	NN
cord-024061-gxv8y146	142	14	)	)	-RRB-
cord-024061-gxv8y146	142	15	is	be	VBZ
cord-024061-gxv8y146	142	16	the	the	DT
cord-024061-gxv8y146	142	17	first	first	JJ
cord-024061-gxv8y146	142	18	stochastic	stochastic	JJ
cord-024061-gxv8y146	142	19	model	model	NN
cord-024061-gxv8y146	142	20	framework	framework	NN
cord-024061-gxv8y146	142	21	aimed	aim	VBN
cord-024061-gxv8y146	142	22	at	at	IN
cord-024061-gxv8y146	142	23	estimating	estimate	VBG
cord-024061-gxv8y146	142	24	the	the	DT
cord-024061-gxv8y146	142	25	size	size	NN
cord-024061-gxv8y146	142	26	of	of	IN
cord-024061-gxv8y146	142	27	the	the	DT
cord-024061-gxv8y146	142	28	sequences	sequence	NNS
cord-024061-gxv8y146	142	29	'	'	POS
cord-024061-gxv8y146	142	30	population	population	NN
cord-024061-gxv8y146	142	31	(	(	-LRB-
cord-024061-gxv8y146	142	32	85	85	CD
cord-024061-gxv8y146	142	33	)	)	-RRB-
cord-024061-gxv8y146	142	34	.	.	.
cord-024061-gxv8y146	143	1	The	the	DT
cord-024061-gxv8y146	143	2	theory	theory	NN
cord-024061-gxv8y146	143	3	describes	describe	VBZ
cord-024061-gxv8y146	143	4	the	the	DT
cord-024061-gxv8y146	143	5	distribution	distribution	NN
cord-024061-gxv8y146	143	6	of	of	IN
cord-024061-gxv8y146	143	7	coalescent	coalescent	JJ
cord-024061-gxv8y146	143	8	times	time	NNS
cord-024061-gxv8y146	143	9	in	in	IN
cord-024061-gxv8y146	143	10	the	the	DT
cord-024061-gxv8y146	143	11	phylogeny	phylogeny	NN
cord-024061-gxv8y146	143	12	as	as	IN
cord-024061-gxv8y146	143	13	a	a	DT
cord-024061-gxv8y146	143	14	function	function	NN
cord-024061-gxv8y146	143	15	of	of	IN
cord-024061-gxv8y146	143	16	the	the	DT
cord-024061-gxv8y146	143	17	size	size	NN
cord-024061-gxv8y146	143	18	of	of	IN
cord-024061-gxv8y146	143	19	the	the	DT
cord-024061-gxv8y146	143	20	population	population	NN
cord-024061-gxv8y146	143	21	from	from	IN
cord-024061-gxv8y146	143	22	which	which	WDT
cord-024061-gxv8y146	143	23	the	the	DT
cord-024061-gxv8y146	143	24	sequences	sequence	NNS
cord-024061-gxv8y146	143	25	were	be	VBD
cord-024061-gxv8y146	143	26	drawn	draw	VBN
cord-024061-gxv8y146	143	27	(	(	-LRB-
cord-024061-gxv8y146	143	28	85	85	CD
cord-024061-gxv8y146	143	29	)	)	-RRB-
cord-024061-gxv8y146	143	30	.	.	.
cord-024061-gxv8y146	144	1	Hence	hence	RB
cord-024061-gxv8y146	144	2	,	,	,
cord-024061-gxv8y146	144	3	in	in	IN
cord-024061-gxv8y146	144	4	the	the	DT
cord-024061-gxv8y146	144	5	past	past	JJ
cord-024061-gxv8y146	144	6	few	few	JJ
cord-024061-gxv8y146	144	7	decades	decade	NNS
cord-024061-gxv8y146	144	8	,	,	,
cord-024061-gxv8y146	144	9	the	the	DT
cord-024061-gxv8y146	144	10	coalescent	coalescent	NN
cord-024061-gxv8y146	144	11	theory	theory	NN
cord-024061-gxv8y146	144	12	is	be	VBZ
cord-024061-gxv8y146	144	13	the	the	DT
cord-024061-gxv8y146	144	14	core	core	NN
cord-024061-gxv8y146	144	15	of	of	IN
cord-024061-gxv8y146	144	16	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	144	17	methods	method	NNS
cord-024061-gxv8y146	144	18	and	and	CC
cord-024061-gxv8y146	144	19	has	have	VBZ
cord-024061-gxv8y146	144	20	shown	show	VBN
cord-024061-gxv8y146	144	21	to	to	TO
cord-024061-gxv8y146	144	22	be	be	VB
cord-024061-gxv8y146	144	23	the	the	DT
cord-024061-gxv8y146	144	24	most	most	RBS
cord-024061-gxv8y146	144	25	useful	useful	JJ
cord-024061-gxv8y146	144	26	for	for	IN
cord-024061-gxv8y146	144	27	inferring	infer	VBG
cord-024061-gxv8y146	144	28	essential	essential	JJ
cord-024061-gxv8y146	144	29	parameters	parameter	NNS
cord-024061-gxv8y146	144	30	that	that	WDT
cord-024061-gxv8y146	144	31	shapes	shape	VBZ
cord-024061-gxv8y146	144	32	the	the	DT
cord-024061-gxv8y146	144	33	evolution	evolution	NN
cord-024061-gxv8y146	144	34	and	and	CC
cord-024061-gxv8y146	144	35	population	population	NN
cord-024061-gxv8y146	144	36	dynamics	dynamic	NNS
cord-024061-gxv8y146	144	37	of	of	IN
cord-024061-gxv8y146	144	38	evolving	evolve	VBG
cord-024061-gxv8y146	144	39	populations	population	NNS
cord-024061-gxv8y146	144	40	including	include	VBG
cord-024061-gxv8y146	144	41	their	-PRON-	PRP$
cord-024061-gxv8y146	144	42	effective	effective	JJ
cord-024061-gxv8y146	144	43	size	size	NN
cord-024061-gxv8y146	144	44	(	(	-LRB-
cord-024061-gxv8y146	144	45	86	86	CD
cord-024061-gxv8y146	144	46	)	)	-RRB-
cord-024061-gxv8y146	144	47	,	,	,
cord-024061-gxv8y146	144	48	rate	rate	NN
cord-024061-gxv8y146	144	49	of	of	IN
cord-024061-gxv8y146	144	50	growth	growth	NN
cord-024061-gxv8y146	144	51	(	(	-LRB-
cord-024061-gxv8y146	144	52	87	87	CD
cord-024061-gxv8y146	144	53	)	)	-RRB-
cord-024061-gxv8y146	144	54	,	,	,
cord-024061-gxv8y146	144	55	structure	structure	NN
cord-024061-gxv8y146	144	56	(	(	-LRB-
cord-024061-gxv8y146	144	57	88	88	CD
cord-024061-gxv8y146	144	58	)	)	-RRB-
cord-024061-gxv8y146	144	59	,	,	,
cord-024061-gxv8y146	144	60	recombination	recombination	NN
cord-024061-gxv8y146	144	61	,	,	,
cord-024061-gxv8y146	144	62	and	and	CC
cord-024061-gxv8y146	144	63	reticulate	reticulate	JJ
cord-024061-gxv8y146	144	64	ancestry	ancestry	NN
cord-024061-gxv8y146	144	65	(	(	-LRB-
cord-024061-gxv8y146	144	66	89	89	CD
cord-024061-gxv8y146	144	67	)	)	-RRB-
cord-024061-gxv8y146	144	68	.	.	.
cord-024061-gxv8y146	145	1	Expanding	expand	VBG
cord-024061-gxv8y146	145	2	the	the	DT
cord-024061-gxv8y146	145	3	temporal	temporal	JJ
cord-024061-gxv8y146	145	4	frame	frame	NN
cord-024061-gxv8y146	145	5	of	of	IN
cord-024061-gxv8y146	145	6	sampling	sampling	NN
cord-024061-gxv8y146	145	7	times	time	NNS
cord-024061-gxv8y146	145	8	is	be	VBZ
cord-024061-gxv8y146	145	9	the	the	DT
cord-024061-gxv8y146	145	10	ultimate	ultimate	JJ
cord-024061-gxv8y146	145	11	approach	approach	NN
cord-024061-gxv8y146	145	12	for	for	IN
cord-024061-gxv8y146	145	13	increasing	increase	VBG
cord-024061-gxv8y146	145	14	the	the	DT
cord-024061-gxv8y146	145	15	statistical	statistical	JJ
cord-024061-gxv8y146	145	16	power	power	NN
cord-024061-gxv8y146	145	17	and	and	CC
cord-024061-gxv8y146	145	18	precision	precision	NN
cord-024061-gxv8y146	145	19	of	of	IN
cord-024061-gxv8y146	145	20	the	the	DT
cord-024061-gxv8y146	145	21	coalescent	coalescent	JJ
cord-024061-gxv8y146	145	22	model	model	NN
cord-024061-gxv8y146	145	23	in	in	IN
cord-024061-gxv8y146	145	24	estimating	estimate	VBG
cord-024061-gxv8y146	145	25	substitution	substitution	NN
cord-024061-gxv8y146	145	26	rates	rate	NNS
cord-024061-gxv8y146	145	27	and	and	CC
cord-024061-gxv8y146	145	28	population	population	NN
cord-024061-gxv8y146	145	29	demographics	demographic	NNS
cord-024061-gxv8y146	145	30	of	of	IN
cord-024061-gxv8y146	145	31	rapidly	rapidly	RB
cord-024061-gxv8y146	145	32	evolving	evolve	VBG
cord-024061-gxv8y146	145	33	viruses	virus	NNS
cord-024061-gxv8y146	145	34	(	(	-LRB-
cord-024061-gxv8y146	145	35	90	90	CD
cord-024061-gxv8y146	145	36	)	)	-RRB-
cord-024061-gxv8y146	145	37	.	.	.
cord-024061-gxv8y146	146	1	An	an	DT
cord-024061-gxv8y146	146	2	essential	essential	JJ
cord-024061-gxv8y146	146	3	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	146	4	parameter	parameter	NN
cord-024061-gxv8y146	146	5	estimated	estimate	VBN
cord-024061-gxv8y146	146	6	from	from	IN
cord-024061-gxv8y146	146	7	the	the	DT
cord-024061-gxv8y146	146	8	coalescent	coalescent	NN
cord-024061-gxv8y146	146	9	model	model	NN
cord-024061-gxv8y146	146	10	is	be	VBZ
cord-024061-gxv8y146	146	11	effective	effective	JJ
cord-024061-gxv8y146	146	12	population	population	NN
cord-024061-gxv8y146	146	13	size	size	NN
cord-024061-gxv8y146	146	14	(	(	-LRB-
cord-024061-gxv8y146	146	15	N	n	NN
cord-024061-gxv8y146	146	16	e	e	NN
cord-024061-gxv8y146	146	17	)	)	-RRB-
cord-024061-gxv8y146	146	18	at	at	IN
cord-024061-gxv8y146	146	19	a	a	DT
cord-024061-gxv8y146	146	20	specific	specific	JJ
cord-024061-gxv8y146	146	21	time	time	NN
cord-024061-gxv8y146	146	22	(	(	-LRB-
cord-024061-gxv8y146	146	23	t	t	NN
cord-024061-gxv8y146	146	24	)	)	-RRB-
cord-024061-gxv8y146	146	25	and	and	CC
cord-024061-gxv8y146	146	26	interpreted	interpret	VBD
cord-024061-gxv8y146	146	27	as	as	IN
cord-024061-gxv8y146	146	28	the	the	DT
cord-024061-gxv8y146	146	29	natural	natural	JJ
cord-024061-gxv8y146	146	30	population	population	NN
cord-024061-gxv8y146	146	31	that	that	WDT
cord-024061-gxv8y146	146	32	represents	represent	VBZ
cord-024061-gxv8y146	146	33	sample	sample	NN
cord-024061-gxv8y146	146	34	genealogies	genealogy	NNS
cord-024061-gxv8y146	146	35	that	that	WDT
cord-024061-gxv8y146	146	36	have	have	VBP
cord-024061-gxv8y146	146	37	statistical	statistical	JJ
cord-024061-gxv8y146	146	38	features	feature	NNS
cord-024061-gxv8y146	146	39	of	of	IN
cord-024061-gxv8y146	146	40	an	an	DT
cord-024061-gxv8y146	146	41	idealized	idealized	JJ
cord-024061-gxv8y146	146	42	population	population	NN
cord-024061-gxv8y146	146	43	size	size	NN
cord-024061-gxv8y146	146	44	through	through	IN
cord-024061-gxv8y146	146	45	time	time	NN
cord-024061-gxv8y146	146	46	N	n	NN
cord-024061-gxv8y146	146	47	e	e	NN
cord-024061-gxv8y146	146	48	(	(	-LRB-
cord-024061-gxv8y146	146	49	t	t	NN
cord-024061-gxv8y146	146	50	)	)	-RRB-
cord-024061-gxv8y146	146	51	(	(	-LRB-
cord-024061-gxv8y146	146	52	84	84	CD
cord-024061-gxv8y146	146	53	)	)	-RRB-
cord-024061-gxv8y146	146	54	.	.	.
cord-024061-gxv8y146	147	1	However	however	RB
cord-024061-gxv8y146	147	2	,	,	,
cord-024061-gxv8y146	147	3	such	such	JJ
cord-024061-gxv8y146	147	4	interpretation	interpretation	NN
cord-024061-gxv8y146	147	5	is	be	VBZ
cord-024061-gxv8y146	147	6	only	only	RB
cord-024061-gxv8y146	147	7	suitable	suitable	JJ
cord-024061-gxv8y146	147	8	for	for	IN
cord-024061-gxv8y146	147	9	a	a	DT
cord-024061-gxv8y146	147	10	non	non	JJ
cord-024061-gxv8y146	147	11	-	-	JJ
cord-024061-gxv8y146	147	12	recombinant	recombinant	JJ
cord-024061-gxv8y146	147	13	single	single	JJ
cord-024061-gxv8y146	147	14	population	population	NN
cord-024061-gxv8y146	147	15	,	,	,
cord-024061-gxv8y146	147	16	whereas	whereas	IN
cord-024061-gxv8y146	147	17	complex	complex	JJ
cord-024061-gxv8y146	147	18	populations	population	NNS
cord-024061-gxv8y146	147	19	with	with	IN
cord-024061-gxv8y146	147	20	more	more	RBR
cord-024061-gxv8y146	147	21	frequent	frequent	JJ
cord-024061-gxv8y146	147	22	recombination	recombination	NN
cord-024061-gxv8y146	147	23	events	event	NNS
cord-024061-gxv8y146	147	24	require	require	VBP
cord-024061-gxv8y146	147	25	the	the	DT
cord-024061-gxv8y146	147	26	use	use	NN
cord-024061-gxv8y146	147	27	of	of	IN
cord-024061-gxv8y146	147	28	structured	structured	JJ
cord-024061-gxv8y146	147	29	tree	tree	NN
cord-024061-gxv8y146	147	30	models	model	NNS
cord-024061-gxv8y146	147	31	(	(	-LRB-
cord-024061-gxv8y146	147	32	84	84	CD
cord-024061-gxv8y146	147	33	)	)	-RRB-
cord-024061-gxv8y146	147	34	described	describe	VBN
cord-024061-gxv8y146	147	35	in	in	IN
cord-024061-gxv8y146	147	36	the	the	DT
cord-024061-gxv8y146	147	37	following	following	JJ
cord-024061-gxv8y146	147	38	section	section	NN
cord-024061-gxv8y146	147	39	.	.	.
cord-024061-gxv8y146	148	1	Estimating	estimate	VBG
cord-024061-gxv8y146	148	2	the	the	DT
cord-024061-gxv8y146	148	3	posterior	posterior	JJ
cord-024061-gxv8y146	148	4	phylogeny	phylogeny	NN
cord-024061-gxv8y146	148	5	of	of	IN
cord-024061-gxv8y146	148	6	a	a	DT
cord-024061-gxv8y146	148	7	well	well	RB
cord-024061-gxv8y146	148	8	-	-	HYPH
cord-024061-gxv8y146	148	9	mixed	mix	VBN
cord-024061-gxv8y146	148	10	population	population	NN
cord-024061-gxv8y146	148	11	with	with	IN
cord-024061-gxv8y146	148	12	changing	change	VBG
cord-024061-gxv8y146	148	13	population	population	NN
cord-024061-gxv8y146	148	14	size	size	NN
cord-024061-gxv8y146	148	15	can	can	MD
cord-024061-gxv8y146	148	16	be	be	VB
cord-024061-gxv8y146	148	17	attained	attain	VBN
cord-024061-gxv8y146	148	18	using	use	VBG
cord-024061-gxv8y146	148	19	either	either	CC
cord-024061-gxv8y146	148	20	parametric	parametric	JJ
cord-024061-gxv8y146	148	21	or	or	CC
cord-024061-gxv8y146	148	22	non	non	JJ
cord-024061-gxv8y146	148	23	-	-	JJ
cord-024061-gxv8y146	148	24	parametric	parametric	JJ
cord-024061-gxv8y146	148	25	node	node	NN
cord-024061-gxv8y146	148	26	-	-	HYPH
cord-024061-gxv8y146	148	27	age	age	NN
cord-024061-gxv8y146	148	28	models	model	NNS
cord-024061-gxv8y146	148	29	(	(	-LRB-
cord-024061-gxv8y146	148	30	84	84	CD
cord-024061-gxv8y146	148	31	)	)	-RRB-
cord-024061-gxv8y146	148	32	.	.	.
cord-024061-gxv8y146	149	1	Parametric	parametric	JJ
cord-024061-gxv8y146	149	2	node	node	NN
cord-024061-gxv8y146	149	3	-	-	HYPH
cord-024061-gxv8y146	149	4	age	age	NN
cord-024061-gxv8y146	149	5	models	model	NNS
cord-024061-gxv8y146	149	6	accommodate	accommodate	VBP
cord-024061-gxv8y146	149	7	standard	standard	JJ
cord-024061-gxv8y146	149	8	continuous	continuous	JJ
cord-024061-gxv8y146	149	9	population	population	NN
cord-024061-gxv8y146	149	10	functions	function	NNS
cord-024061-gxv8y146	149	11	,	,	,
cord-024061-gxv8y146	149	12	the	the	DT
cord-024061-gxv8y146	149	13	simplest	simple	JJS
cord-024061-gxv8y146	149	14	and	and	CC
cord-024061-gxv8y146	149	15	most	most	RBS
cord-024061-gxv8y146	149	16	naïve	naïve	JJ
cord-024061-gxv8y146	149	17	,	,	,
cord-024061-gxv8y146	149	18	namely	namely	RB
cord-024061-gxv8y146	149	19	,	,	,
cord-024061-gxv8y146	149	20	the	the	DT
cord-024061-gxv8y146	149	21	constant	constant	JJ
cord-024061-gxv8y146	149	22	population	population	NN
cord-024061-gxv8y146	149	23	growth	growth	NN
cord-024061-gxv8y146	149	24	(	(	-LRB-
cord-024061-gxv8y146	149	25	CP	CP	NNP
cord-024061-gxv8y146	149	26	)	)	-RRB-
cord-024061-gxv8y146	149	27	,	,	,
cord-024061-gxv8y146	149	28	which	which	WDT
cord-024061-gxv8y146	149	29	assumes	assume	VBZ
cord-024061-gxv8y146	149	30	that	that	IN
cord-024061-gxv8y146	149	31	the	the	DT
cord-024061-gxv8y146	149	32	population	population	NN
cord-024061-gxv8y146	149	33	growth	growth	NN
cord-024061-gxv8y146	149	34	rate	rate	NN
cord-024061-gxv8y146	149	35	is	be	VBZ
cord-024061-gxv8y146	149	36	zero	zero	CD
cord-024061-gxv8y146	149	37	(	(	-LRB-
cord-024061-gxv8y146	149	38	91	91	CD
cord-024061-gxv8y146	149	39	)	)	-RRB-
cord-024061-gxv8y146	149	40	.	.	.
cord-024061-gxv8y146	150	1	The	the	DT
cord-024061-gxv8y146	150	2	other	other	JJ
cord-024061-gxv8y146	150	3	three	three	CD
cord-024061-gxv8y146	150	4	parametric	parametric	JJ
cord-024061-gxv8y146	150	5	models	model	NNS
cord-024061-gxv8y146	150	6	include	include	VBP
cord-024061-gxv8y146	150	7	the	the	DT
cord-024061-gxv8y146	150	8	logistic	logistic	JJ
cord-024061-gxv8y146	150	9	(	(	-LRB-
cord-024061-gxv8y146	150	10	LG	LG	NNP
cord-024061-gxv8y146	150	11	)	)	-RRB-
cord-024061-gxv8y146	150	12	growth	growth	NN
cord-024061-gxv8y146	150	13	(	(	-LRB-
cord-024061-gxv8y146	150	14	assumes	assume	VBZ
cord-024061-gxv8y146	150	15	the	the	DT
cord-024061-gxv8y146	150	16	population	population	NN
cord-024061-gxv8y146	150	17	growth	growth	NN
cord-024061-gxv8y146	150	18	rate	rate	NN
cord-024061-gxv8y146	150	19	is	be	VBZ
cord-024061-gxv8y146	150	20	decreasing	decrease	VBG
cord-024061-gxv8y146	150	21	over	over	IN
cord-024061-gxv8y146	150	22	time	time	NN
cord-024061-gxv8y146	150	23	)	)	-RRB-
cord-024061-gxv8y146	150	24	,	,	,
cord-024061-gxv8y146	150	25	exponential	exponential	JJ
cord-024061-gxv8y146	150	26	(	(	-LRB-
cord-024061-gxv8y146	150	27	EX	ex	NN
cord-024061-gxv8y146	150	28	)	)	-RRB-
cord-024061-gxv8y146	150	29	growth	growth	NN
cord-024061-gxv8y146	150	30	(	(	-LRB-
cord-024061-gxv8y146	150	31	assumes	assume	VBZ
cord-024061-gxv8y146	150	32	the	the	DT
cord-024061-gxv8y146	150	33	population	population	NN
cord-024061-gxv8y146	150	34	growth	growth	NN
cord-024061-gxv8y146	150	35	rate	rate	NN
cord-024061-gxv8y146	150	36	is	be	VBZ
cord-024061-gxv8y146	150	37	fixed	fix	VBN
cord-024061-gxv8y146	150	38	over	over	IN
cord-024061-gxv8y146	150	39	time	time	NN
cord-024061-gxv8y146	150	40	)	)	-RRB-
cord-024061-gxv8y146	150	41	,	,	,
cord-024061-gxv8y146	150	42	and	and	CC
cord-024061-gxv8y146	150	43	the	the	DT
cord-024061-gxv8y146	150	44	expansion	expansion	NN
cord-024061-gxv8y146	150	45	(	(	-LRB-
cord-024061-gxv8y146	150	46	EGx	egx	NN
cord-024061-gxv8y146	150	47	)	)	-RRB-
cord-024061-gxv8y146	150	48	growth	growth	NN
cord-024061-gxv8y146	150	49	(	(	-LRB-
cord-024061-gxv8y146	150	50	assumes	assume	VBZ
cord-024061-gxv8y146	150	51	the	the	DT
cord-024061-gxv8y146	150	52	population	population	NN
cord-024061-gxv8y146	150	53	growth	growth	NN
cord-024061-gxv8y146	150	54	rate	rate	NN
cord-024061-gxv8y146	150	55	is	be	VBZ
cord-024061-gxv8y146	150	56	increasing	increase	VBG
cord-024061-gxv8y146	150	57	over	over	IN
cord-024061-gxv8y146	150	58	time	time	NN
cord-024061-gxv8y146	150	59	)	)	-RRB-
cord-024061-gxv8y146	150	60	(	(	-LRB-
cord-024061-gxv8y146	150	61	91	91	CD
cord-024061-gxv8y146	150	62	)	)	-RRB-
cord-024061-gxv8y146	150	63	.	.	.
cord-024061-gxv8y146	151	1	One	one	PRP
cord-024061-gxv8y146	151	2	would	would	MD
cord-024061-gxv8y146	151	3	expect	expect	VB
cord-024061-gxv8y146	151	4	,	,	,
cord-024061-gxv8y146	151	5	in	in	IN
cord-024061-gxv8y146	151	6	the	the	DT
cord-024061-gxv8y146	151	7	event	event	NN
cord-024061-gxv8y146	151	8	of	of	IN
cord-024061-gxv8y146	151	9	an	an	DT
cord-024061-gxv8y146	151	10	epidemic	epidemic	NN
cord-024061-gxv8y146	151	11	caused	cause	VBN
cord-024061-gxv8y146	151	12	by	by	IN
cord-024061-gxv8y146	151	13	a	a	DT
cord-024061-gxv8y146	151	14	rapidly	rapidly	RB
cord-024061-gxv8y146	151	15	evolving	evolve	VBG
cord-024061-gxv8y146	151	16	virus	virus	NN
cord-024061-gxv8y146	151	17	like	like	IN
cord-024061-gxv8y146	151	18	influenza	influenza	NN
cord-024061-gxv8y146	151	19	and	and	CC
cord-024061-gxv8y146	151	20	in	in	IN
cord-024061-gxv8y146	151	21	the	the	DT
cord-024061-gxv8y146	151	22	absence	absence	NN
cord-024061-gxv8y146	151	23	of	of	IN
cord-024061-gxv8y146	151	24	new	new	JJ
cord-024061-gxv8y146	151	25	vaccination	vaccination	NN
cord-024061-gxv8y146	151	26	,	,	,
cord-024061-gxv8y146	151	27	the	the	DT
cord-024061-gxv8y146	151	28	population	population	NN
cord-024061-gxv8y146	151	29	growth	growth	NN
cord-024061-gxv8y146	151	30	rate	rate	NN
cord-024061-gxv8y146	151	31	of	of	IN
cord-024061-gxv8y146	151	32	the	the	DT
cord-024061-gxv8y146	151	33	virus	virus	NN
cord-024061-gxv8y146	151	34	would	would	MD
cord-024061-gxv8y146	151	35	realistically	realistically	RB
cord-024061-gxv8y146	151	36	fit	fit	VB
cord-024061-gxv8y146	151	37	either	either	CC
cord-024061-gxv8y146	151	38	an	an	DT
cord-024061-gxv8y146	151	39	exponential	exponential	JJ
cord-024061-gxv8y146	151	40	or	or	CC
cord-024061-gxv8y146	151	41	an	an	DT
cord-024061-gxv8y146	151	42	expansion	expansion	NN
cord-024061-gxv8y146	151	43	growth	growth	NN
cord-024061-gxv8y146	151	44	rate	rate	NN
cord-024061-gxv8y146	151	45	model	model	NN
cord-024061-gxv8y146	151	46	(	(	-LRB-
cord-024061-gxv8y146	151	47	44	44	CD
cord-024061-gxv8y146	151	48	,	,	,
cord-024061-gxv8y146	151	49	92	92	CD
cord-024061-gxv8y146	151	50	)	)	-RRB-
cord-024061-gxv8y146	151	51	.	.	.
cord-024061-gxv8y146	152	1	Unlike	unlike	IN
cord-024061-gxv8y146	152	2	parametric	parametric	JJ
cord-024061-gxv8y146	152	3	node	node	NN
cord-024061-gxv8y146	152	4	-	-	HYPH
cord-024061-gxv8y146	152	5	age	age	NN
cord-024061-gxv8y146	152	6	models	model	NNS
cord-024061-gxv8y146	152	7	,	,	,
cord-024061-gxv8y146	152	8	non	non	JJ
cord-024061-gxv8y146	152	9	-	-	JJ
cord-024061-gxv8y146	152	10	parametric	parametric	JJ
cord-024061-gxv8y146	152	11	models	model	NNS
cord-024061-gxv8y146	152	12	can	can	MD
cord-024061-gxv8y146	152	13	be	be	VB
cord-024061-gxv8y146	152	14	used	use	VBN
cord-024061-gxv8y146	152	15	to	to	TO
cord-024061-gxv8y146	152	16	visually	visually	RB
cord-024061-gxv8y146	152	17	infer	infer	VB
cord-024061-gxv8y146	152	18	the	the	DT
cord-024061-gxv8y146	152	19	history	history	NN
cord-024061-gxv8y146	152	20	of	of	IN
cord-024061-gxv8y146	152	21	population	population	NN
cord-024061-gxv8y146	152	22	size	size	NN
cord-024061-gxv8y146	152	23	through	through	IN
cord-024061-gxv8y146	152	24	time	time	NN
cord-024061-gxv8y146	152	25	(	(	-LRB-
cord-024061-gxv8y146	152	26	i.e.	i.e.	FW
cord-024061-gxv8y146	152	27	,	,	,
cord-024061-gxv8y146	152	28	genetic	genetic	JJ
cord-024061-gxv8y146	152	29	diversity	diversity	NN
cord-024061-gxv8y146	152	30	)	)	-RRB-
cord-024061-gxv8y146	152	31	from	from	IN
cord-024061-gxv8y146	152	32	the	the	DT
cord-024061-gxv8y146	152	33	sequence	sequence	NN
cord-024061-gxv8y146	152	34	data	datum	NNS
cord-024061-gxv8y146	152	35	in	in	IN
cord-024061-gxv8y146	152	36	terms	term	NNS
cord-024061-gxv8y146	152	37	of	of	IN
cord-024061-gxv8y146	152	38	inclines	incline	NNS
cord-024061-gxv8y146	152	39	and	and	CC
cord-024061-gxv8y146	152	40	declines	decline	NNS
cord-024061-gxv8y146	152	41	(	(	-LRB-
cord-024061-gxv8y146	152	42	93	93	CD
cord-024061-gxv8y146	152	43	)	)	-RRB-
cord-024061-gxv8y146	152	44	.	.	.
cord-024061-gxv8y146	153	1	These	these	DT
cord-024061-gxv8y146	153	2	models	model	NNS
cord-024061-gxv8y146	153	3	treat	treat	VBP
cord-024061-gxv8y146	153	4	each	each	DT
cord-024061-gxv8y146	153	5	coalescent	coalescent	JJ
cord-024061-gxv8y146	153	6	interval	interval	NN
cord-024061-gxv8y146	153	7	as	as	IN
cord-024061-gxv8y146	153	8	a	a	DT
cord-024061-gxv8y146	153	9	separate	separate	JJ
cord-024061-gxv8y146	153	10	segment	segment	NN
cord-024061-gxv8y146	153	11	to	to	TO
cord-024061-gxv8y146	153	12	represent	represent	VB
cord-024061-gxv8y146	153	13	a	a	DT
cord-024061-gxv8y146	153	14	parameter	parameter	NN
cord-024061-gxv8y146	153	15	for	for	IN
cord-024061-gxv8y146	153	16	population	population	NN
cord-024061-gxv8y146	153	17	size	size	NN
cord-024061-gxv8y146	153	18	in	in	IN
cord-024061-gxv8y146	153	19	a	a	DT
cord-024061-gxv8y146	153	20	given	give	VBN
cord-024061-gxv8y146	153	21	time	time	NN
cord-024061-gxv8y146	153	22	,	,	,
cord-024061-gxv8y146	153	23	in	in	IN
cord-024061-gxv8y146	153	24	which	which	WDT
cord-024061-gxv8y146	153	25	the	the	DT
cord-024061-gxv8y146	153	26	number	number	NN
cord-024061-gxv8y146	153	27	of	of	IN
cord-024061-gxv8y146	153	28	segments	segment	NNS
cord-024061-gxv8y146	153	29	can	can	MD
cord-024061-gxv8y146	153	30	be	be	VB
cord-024061-gxv8y146	153	31	specified	specify	VBN
cord-024061-gxv8y146	153	32	by	by	IN
cord-024061-gxv8y146	153	33	the	the	DT
cord-024061-gxv8y146	153	34	investigator	investigator	NN
cord-024061-gxv8y146	153	35	to	to	TO
cord-024061-gxv8y146	153	36	generate	generate	VB
cord-024061-gxv8y146	153	37	a	a	DT
cord-024061-gxv8y146	153	38	sky	sky	NN
cord-024061-gxv8y146	153	39	plot	plot	NN
cord-024061-gxv8y146	153	40	(	(	-LRB-
cord-024061-gxv8y146	153	41	93	93	CD
cord-024061-gxv8y146	153	42	)	)	-RRB-
cord-024061-gxv8y146	153	43	.	.	.
cord-024061-gxv8y146	154	1	The	the	DT
cord-024061-gxv8y146	154	2	piece	piece	NN
cord-024061-gxv8y146	154	3	-	-	HYPH
cord-024061-gxv8y146	154	4	wise	wise	JJ
cord-024061-gxv8y146	154	5	constant	constant	JJ
cord-024061-gxv8y146	154	6	Bayesian	bayesian	JJ
cord-024061-gxv8y146	154	7	skyline	skyline	NN
cord-024061-gxv8y146	154	8	(	(	-LRB-
cord-024061-gxv8y146	154	9	BS	BS	NNP
cord-024061-gxv8y146	154	10	)	)	-RRB-
cord-024061-gxv8y146	154	11	is	be	VBZ
cord-024061-gxv8y146	154	12	the	the	DT
cord-024061-gxv8y146	154	13	simplest	simple	JJS
cord-024061-gxv8y146	154	14	non	non	JJ
cord-024061-gxv8y146	154	15	-	-	JJ
cord-024061-gxv8y146	154	16	parametric	parametric	JJ
cord-024061-gxv8y146	154	17	model	model	NN
cord-024061-gxv8y146	154	18	,	,	,
cord-024061-gxv8y146	154	19	which	which	WDT
cord-024061-gxv8y146	154	20	assumes	assume	VBZ
cord-024061-gxv8y146	154	21	that	that	IN
cord-024061-gxv8y146	154	22	the	the	DT
cord-024061-gxv8y146	154	23	effective	effective	JJ
cord-024061-gxv8y146	154	24	population	population	NN
cord-024061-gxv8y146	154	25	size	size	NN
cord-024061-gxv8y146	154	26	is	be	VBZ
cord-024061-gxv8y146	154	27	experiencing	experience	VBG
cord-024061-gxv8y146	154	28	an	an	DT
cord-024061-gxv8y146	154	29	episodic	episodic	JJ
cord-024061-gxv8y146	154	30	stepwise	stepwise	JJ
cord-024061-gxv8y146	154	31	changes	change	NNS
cord-024061-gxv8y146	154	32	through	through	IN
cord-024061-gxv8y146	154	33	time	time	NN
cord-024061-gxv8y146	154	34	(	(	-LRB-
cord-024061-gxv8y146	154	35	93	93	CD
cord-024061-gxv8y146	154	36	)	)	-RRB-
cord-024061-gxv8y146	154	37	.	.	.
cord-024061-gxv8y146	155	1	However	however	RB
cord-024061-gxv8y146	155	2	,	,	,
cord-024061-gxv8y146	155	3	the	the	DT
cord-024061-gxv8y146	155	4	BS	BS	NNP
cord-024061-gxv8y146	155	5	model	model	NN
cord-024061-gxv8y146	155	6	is	be	VBZ
cord-024061-gxv8y146	155	7	shown	show	VBN
cord-024061-gxv8y146	155	8	to	to	TO
cord-024061-gxv8y146	155	9	be	be	VB
cord-024061-gxv8y146	155	10	very	very	RB
cord-024061-gxv8y146	155	11	sensitive	sensitive	JJ
cord-024061-gxv8y146	155	12	to	to	IN
cord-024061-gxv8y146	155	13	the	the	DT
cord-024061-gxv8y146	155	14	total	total	JJ
cord-024061-gxv8y146	155	15	number	number	NN
cord-024061-gxv8y146	155	16	of	of	IN
cord-024061-gxv8y146	155	17	change	change	NN
cord-024061-gxv8y146	155	18	points	point	NNS
cord-024061-gxv8y146	155	19	(	(	-LRB-
cord-024061-gxv8y146	155	20	i.e.	i.e.	FW
cord-024061-gxv8y146	155	21	,	,	,
cord-024061-gxv8y146	155	22	coalescent	coalescent	NN
cord-024061-gxv8y146	155	23	intervals	interval	NNS
cord-024061-gxv8y146	155	24	)	)	-RRB-
cord-024061-gxv8y146	155	25	when	when	WRB
cord-024061-gxv8y146	155	26	specified	specify	VBN
cord-024061-gxv8y146	155	27	as	as	IN
cord-024061-gxv8y146	155	28	a	a	DT
cord-024061-gxv8y146	155	29	prior	prior	NN
cord-024061-gxv8y146	155	30	as	as	RB
cord-024061-gxv8y146	155	31	well	well	RB
cord-024061-gxv8y146	155	32	as	as	IN
cord-024061-gxv8y146	155	33	to	to	IN
cord-024061-gxv8y146	155	34	the	the	DT
cord-024061-gxv8y146	155	35	number	number	NN
cord-024061-gxv8y146	155	36	of	of	IN
cord-024061-gxv8y146	155	37	sequences	sequence	NNS
cord-024061-gxv8y146	155	38	sampled	sample	VBN
cord-024061-gxv8y146	155	39	at	at	IN
cord-024061-gxv8y146	155	40	each	each	DT
cord-024061-gxv8y146	155	41	point	point	NN
cord-024061-gxv8y146	155	42	of	of	IN
cord-024061-gxv8y146	155	43	time	time	NN
cord-024061-gxv8y146	155	44	(	(	-LRB-
cord-024061-gxv8y146	155	45	94	94	CD
cord-024061-gxv8y146	155	46	)	)	-RRB-
cord-024061-gxv8y146	155	47	.	.	.
cord-024061-gxv8y146	156	1	Hence	hence	RB
cord-024061-gxv8y146	156	2	,	,	,
cord-024061-gxv8y146	156	3	a	a	DT
cord-024061-gxv8y146	156	4	Gaussian	Gaussian	NNP
cord-024061-gxv8y146	156	5	Markov	Markov	NNP
cord-024061-gxv8y146	156	6	random	random	JJ
cord-024061-gxv8y146	156	7	fields	field	NNS
cord-024061-gxv8y146	156	8	Bayesian	Bayesian	NNP
cord-024061-gxv8y146	156	9	Skyride	Skyride	NNP
cord-024061-gxv8y146	156	10	(	(	-LRB-
cord-024061-gxv8y146	156	11	GMRF	GMRF	NNP
cord-024061-gxv8y146	156	12	)	)	-RRB-
cord-024061-gxv8y146	156	13	was	be	VBD
cord-024061-gxv8y146	156	14	proposed	propose	VBN
cord-024061-gxv8y146	156	15	as	as	IN
cord-024061-gxv8y146	156	16	an	an	DT
cord-024061-gxv8y146	156	17	alternative	alternative	JJ
cord-024061-gxv8y146	156	18	model	model	NN
cord-024061-gxv8y146	156	19	to	to	IN
cord-024061-gxv8y146	156	20	BS	BS	NNP
cord-024061-gxv8y146	156	21	(	(	-LRB-
cord-024061-gxv8y146	156	22	95	95	CD
cord-024061-gxv8y146	156	23	)	)	-RRB-
cord-024061-gxv8y146	156	24	.	.	.
cord-024061-gxv8y146	157	1	The	the	DT
cord-024061-gxv8y146	157	2	GMRF	GMRF	NNP
cord-024061-gxv8y146	157	3	model	model	NN
cord-024061-gxv8y146	157	4	is	be	VBZ
cord-024061-gxv8y146	157	5	less	less	RBR
cord-024061-gxv8y146	157	6	sensitive	sensitive	JJ
cord-024061-gxv8y146	157	7	to	to	IN
cord-024061-gxv8y146	157	8	the	the	DT
cord-024061-gxv8y146	157	9	prior	prior	JJ
cord-024061-gxv8y146	157	10	number	number	NN
cord-024061-gxv8y146	157	11	of	of	IN
cord-024061-gxv8y146	157	12	change	change	NN
cord-024061-gxv8y146	157	13	points	point	NNS
cord-024061-gxv8y146	157	14	because	because	IN
cord-024061-gxv8y146	157	15	it	-PRON-	PRP
cord-024061-gxv8y146	157	16	implements	implement	VBZ
cord-024061-gxv8y146	157	17	a	a	DT
cord-024061-gxv8y146	157	18	temporal	temporal	JJ
cord-024061-gxv8y146	157	19	smoothing	smoothing	NN
cord-024061-gxv8y146	157	20	approach	approach	NN
cord-024061-gxv8y146	157	21	to	to	TO
cord-024061-gxv8y146	157	22	recover	recover	VB
cord-024061-gxv8y146	157	23	accurate	accurate	JJ
cord-024061-gxv8y146	157	24	population	population	NN
cord-024061-gxv8y146	157	25	size	size	NN
cord-024061-gxv8y146	157	26	trajectories	trajectory	NNS
cord-024061-gxv8y146	157	27	(	(	-LRB-
cord-024061-gxv8y146	157	28	95	95	CD
cord-024061-gxv8y146	157	29	)	)	-RRB-
cord-024061-gxv8y146	157	30	.	.	.
cord-024061-gxv8y146	158	1	However	however	RB
cord-024061-gxv8y146	158	2	,	,	,
cord-024061-gxv8y146	158	3	an	an	DT
cord-024061-gxv8y146	158	4	improved	improved	JJ
cord-024061-gxv8y146	158	5	version	version	NN
cord-024061-gxv8y146	158	6	of	of	IN
cord-024061-gxv8y146	158	7	the	the	DT
cord-024061-gxv8y146	158	8	GMRF	GMRF	NNP
cord-024061-gxv8y146	158	9	is	be	VBZ
cord-024061-gxv8y146	158	10	the	the	DT
cord-024061-gxv8y146	158	11	Skygrid	Skygrid	NNP
cord-024061-gxv8y146	158	12	(	(	-LRB-
cord-024061-gxv8y146	158	13	SG	SG	NNP
cord-024061-gxv8y146	158	14	)	)	-RRB-
cord-024061-gxv8y146	158	15	,	,	,
cord-024061-gxv8y146	158	16	which	which	WDT
cord-024061-gxv8y146	158	17	takes	take	VBZ
cord-024061-gxv8y146	158	18	into	into	IN
cord-024061-gxv8y146	158	19	account	account	NN
cord-024061-gxv8y146	158	20	mutation	mutation	NN
cord-024061-gxv8y146	158	21	parameters	parameter	NNS
cord-024061-gxv8y146	158	22	of	of	IN
cord-024061-gxv8y146	158	23	multi	multi	JJ
cord-024061-gxv8y146	158	24	-	-	JJ
cord-024061-gxv8y146	158	25	locus	locus	NN
cord-024061-gxv8y146	158	26	sequences	sequence	NNS
cord-024061-gxv8y146	158	27	(	(	-LRB-
cord-024061-gxv8y146	158	28	33	33	CD
cord-024061-gxv8y146	158	29	)	)	-RRB-
cord-024061-gxv8y146	158	30	.	.	.
cord-024061-gxv8y146	159	1	The	the	DT
cord-024061-gxv8y146	159	2	SG	SG	NNP
cord-024061-gxv8y146	159	3	provides	provide	VBZ
cord-024061-gxv8y146	159	4	a	a	DT
cord-024061-gxv8y146	159	5	more	more	RBR
cord-024061-gxv8y146	159	6	realistic	realistic	JJ
cord-024061-gxv8y146	159	7	estimate	estimate	NN
cord-024061-gxv8y146	159	8	of	of	IN
cord-024061-gxv8y146	159	9	demographic	demographic	JJ
cord-024061-gxv8y146	159	10	history	history	NN
cord-024061-gxv8y146	159	11	in	in	IN
cord-024061-gxv8y146	159	12	terms	term	NNS
cord-024061-gxv8y146	159	13	of	of	IN
cord-024061-gxv8y146	159	14	population	population	NN
cord-024061-gxv8y146	159	15	size	size	NN
cord-024061-gxv8y146	159	16	and	and	CC
cord-024061-gxv8y146	159	17	divergence	divergence	NN
cord-024061-gxv8y146	159	18	times	time	NNS
cord-024061-gxv8y146	159	19	,	,	,
cord-024061-gxv8y146	159	20	as	as	RB
cord-024061-gxv8y146	159	21	well	well	RB
cord-024061-gxv8y146	159	22	as	as	IN
cord-024061-gxv8y146	159	23	flexibility	flexibility	NN
cord-024061-gxv8y146	159	24	in	in	IN
cord-024061-gxv8y146	159	25	terms	term	NNS
cord-024061-gxv8y146	159	26	of	of	IN
cord-024061-gxv8y146	159	27	the	the	DT
cord-024061-gxv8y146	159	28	ability	ability	NN
cord-024061-gxv8y146	159	29	to	to	TO
cord-024061-gxv8y146	159	30	specify	specify	VB
cord-024061-gxv8y146	159	31	cut	cut	VBN
cord-024061-gxv8y146	159	32	-	-	HYPH
cord-024061-gxv8y146	159	33	points	point	NNS
cord-024061-gxv8y146	159	34	to	to	IN
cord-024061-gxv8y146	159	35	the	the	DT
cord-024061-gxv8y146	159	36	time	time	NN
cord-024061-gxv8y146	159	37	trajectories	trajectory	NNS
cord-024061-gxv8y146	159	38	(	(	-LRB-
cord-024061-gxv8y146	159	39	33	33	CD
cord-024061-gxv8y146	159	40	)	)	-RRB-
cord-024061-gxv8y146	159	41	.	.	.
cord-024061-gxv8y146	160	1	Furthermore	furthermore	RB
cord-024061-gxv8y146	160	2	,	,	,
cord-024061-gxv8y146	160	3	the	the	DT
cord-024061-gxv8y146	160	4	SG	SG	NNP
cord-024061-gxv8y146	160	5	model	model	NN
cord-024061-gxv8y146	160	6	is	be	VBZ
cord-024061-gxv8y146	160	7	the	the	DT
cord-024061-gxv8y146	160	8	least	least	JJS
cord-024061-gxv8y146	160	9	sensitive	sensitive	JJ
cord-024061-gxv8y146	160	10	to	to	IN
cord-024061-gxv8y146	160	11	the	the	DT
cord-024061-gxv8y146	160	12	temporal	temporal	JJ
cord-024061-gxv8y146	160	13	distribution	distribution	NN
cord-024061-gxv8y146	160	14	of	of	IN
cord-024061-gxv8y146	160	15	sequences	sequence	NNS
cord-024061-gxv8y146	160	16	(	(	-LRB-
cord-024061-gxv8y146	160	17	33	33	CD
cord-024061-gxv8y146	160	18	)	)	-RRB-
cord-024061-gxv8y146	160	19	.	.	.
cord-024061-gxv8y146	161	1	A	a	DT
cord-024061-gxv8y146	161	2	notable	notable	JJ
cord-024061-gxv8y146	161	3	example	example	NN
cord-024061-gxv8y146	161	4	of	of	IN
cord-024061-gxv8y146	161	5	sky	sky	NN
cord-024061-gxv8y146	161	6	plots	plot	VBZ
cord-024061-gxv8y146	161	7	utility	utility	NN
cord-024061-gxv8y146	161	8	in	in	IN
cord-024061-gxv8y146	161	9	PRRS	PRRS	NNP
cord-024061-gxv8y146	161	10	virus	virus	NN
cord-024061-gxv8y146	161	11	molecular	molecular	JJ
cord-024061-gxv8y146	161	12	surveillance	surveillance	NN
cord-024061-gxv8y146	161	13	in	in	IN
cord-024061-gxv8y146	161	14	the	the	DT
cord-024061-gxv8y146	161	15	United	United	NNP
cord-024061-gxv8y146	161	16	States	States	NNP
cord-024061-gxv8y146	161	17	was	be	VBD
cord-024061-gxv8y146	161	18	demonstrated	demonstrate	VBN
cord-024061-gxv8y146	161	19	by	by	IN
cord-024061-gxv8y146	161	20	Alkhamis	Alkhamis	NNP
cord-024061-gxv8y146	161	21	et	et	NNP
cord-024061-gxv8y146	161	22	al	al	NNP
cord-024061-gxv8y146	161	23	.	.	.
cord-024061-gxv8y146	162	1	(	(	-LRB-
cord-024061-gxv8y146	162	2	21	21	CD
cord-024061-gxv8y146	162	3	)	)	-RRB-
cord-024061-gxv8y146	162	4	and	and	CC
cord-024061-gxv8y146	162	5	Alkhamis	Alkhamis	NNP
cord-024061-gxv8y146	162	6	et	et	NNP
cord-024061-gxv8y146	162	7	al	al	NNP
cord-024061-gxv8y146	162	8	.	.	.
cord-024061-gxv8y146	163	1	(	(	-LRB-
cord-024061-gxv8y146	163	2	37	37	CD
cord-024061-gxv8y146	163	3	)	)	-RRB-
cord-024061-gxv8y146	163	4	.	.	.
cord-024061-gxv8y146	164	1	Their	-PRON-	PRP$
cord-024061-gxv8y146	164	2	sky	sky	NN
cord-024061-gxv8y146	164	3	plot	plot	NN
cord-024061-gxv8y146	164	4	inferred	infer	VBD
cord-024061-gxv8y146	164	5	a	a	DT
cord-024061-gxv8y146	164	6	distinctly	distinctly	RB
cord-024061-gxv8y146	164	7	high	high	JJ
cord-024061-gxv8y146	164	8	genetic	genetic	JJ
cord-024061-gxv8y146	164	9	diversity	diversity	NN
cord-024061-gxv8y146	164	10	through	through	IN
cord-024061-gxv8y146	164	11	time	time	NN
cord-024061-gxv8y146	164	12	for	for	IN
cord-024061-gxv8y146	164	13	the	the	DT
cord-024061-gxv8y146	164	14	emerging	emerge	VBG
cord-024061-gxv8y146	164	15	1	1	CD
cord-024061-gxv8y146	164	16	-	-	HYPH
cord-024061-gxv8y146	164	17	7	7	CD
cord-024061-gxv8y146	164	18	-	-	SYM
cord-024061-gxv8y146	164	19	4	4	CD
cord-024061-gxv8y146	164	20	RFLP	rflp	JJ
cord-024061-gxv8y146	164	21	-	-	HYPH
cord-024061-gxv8y146	164	22	type	type	NN
cord-024061-gxv8y146	164	23	PRRV	PRRV	NNP
cord-024061-gxv8y146	164	24	virus	virus	NN
cord-024061-gxv8y146	164	25	(	(	-LRB-
cord-024061-gxv8y146	164	26	37	37	CD
cord-024061-gxv8y146	164	27	)	)	-RRB-
cord-024061-gxv8y146	164	28	,	,	,
cord-024061-gxv8y146	164	29	while	while	IN
cord-024061-gxv8y146	164	30	inferred	infer	VBN
cord-024061-gxv8y146	164	31	consistent	consistent	JJ
cord-024061-gxv8y146	164	32	seasonal	seasonal	JJ
cord-024061-gxv8y146	164	33	increases	increase	NNS
cord-024061-gxv8y146	164	34	and	and	CC
cord-024061-gxv8y146	164	35	decreases	decrease	NNS
cord-024061-gxv8y146	164	36	in	in	IN
cord-024061-gxv8y146	164	37	the	the	DT
cord-024061-gxv8y146	164	38	relative	relative	JJ
cord-024061-gxv8y146	164	39	genetic	genetic	JJ
cord-024061-gxv8y146	164	40	diversity	diversity	NN
cord-024061-gxv8y146	164	41	through	through	IN
cord-024061-gxv8y146	164	42	time	time	NN
cord-024061-gxv8y146	164	43	for	for	IN
cord-024061-gxv8y146	164	44	endemic	endemic	JJ
cord-024061-gxv8y146	164	45	strains	strain	NNS
cord-024061-gxv8y146	164	46	isolated	isolate	VBN
cord-024061-gxv8y146	164	47	between	between	IN
cord-024061-gxv8y146	164	48	2014	2014	CD
cord-024061-gxv8y146	164	49	and	and	CC
cord-024061-gxv8y146	164	50	2015	2015	CD
cord-024061-gxv8y146	164	51	(	(	-LRB-
cord-024061-gxv8y146	164	52	21	21	CD
cord-024061-gxv8y146	164	53	)	)	-RRB-
cord-024061-gxv8y146	164	54	.	.	.
cord-024061-gxv8y146	165	1	Mugration	mugration	NN
cord-024061-gxv8y146	165	2	models	model	NNS
cord-024061-gxv8y146	165	3	are	be	VBP
cord-024061-gxv8y146	165	4	substitution	substitution	NN
cord-024061-gxv8y146	165	5	models	model	NNS
cord-024061-gxv8y146	165	6	used	use	VBN
cord-024061-gxv8y146	165	7	to	to	TO
cord-024061-gxv8y146	165	8	infer	infer	VB
cord-024061-gxv8y146	165	9	the	the	DT
cord-024061-gxv8y146	165	10	migration	migration	NN
cord-024061-gxv8y146	165	11	processes	process	NNS
cord-024061-gxv8y146	165	12	of	of	IN
cord-024061-gxv8y146	165	13	evolving	evolve	VBG
cord-024061-gxv8y146	165	14	organisms	organism	NNS
cord-024061-gxv8y146	165	15	(	(	-LRB-
cord-024061-gxv8y146	165	16	96	96	CD
cord-024061-gxv8y146	165	17	)	)	-RRB-
cord-024061-gxv8y146	165	18	.	.	.
cord-024061-gxv8y146	166	1	The	the	DT
cord-024061-gxv8y146	166	2	most	most	RBS
cord-024061-gxv8y146	166	3	notable	notable	JJ
cord-024061-gxv8y146	166	4	implementation	implementation	NN
cord-024061-gxv8y146	166	5	of	of	IN
cord-024061-gxv8y146	166	6	a	a	DT
cord-024061-gxv8y146	166	7	migration	migration	NN
cord-024061-gxv8y146	166	8	model	model	NN
cord-024061-gxv8y146	166	9	was	be	VBD
cord-024061-gxv8y146	166	10	developed	develop	VBN
cord-024061-gxv8y146	166	11	by	by	IN
cord-024061-gxv8y146	166	12	Lemey	Lemey	NNP
cord-024061-gxv8y146	166	13	et	et	NNP
cord-024061-gxv8y146	166	14	al	al	NNP
cord-024061-gxv8y146	166	15	.	.	.
cord-024061-gxv8y146	167	1	(	(	-LRB-
cord-024061-gxv8y146	167	2	97	97	CD
cord-024061-gxv8y146	167	3	)	)	-RRB-
cord-024061-gxv8y146	167	4	using	use	VBG
cord-024061-gxv8y146	167	5	a	a	DT
cord-024061-gxv8y146	167	6	CTMP	CTMP	NNP
cord-024061-gxv8y146	167	7	to	to	TO
cord-024061-gxv8y146	167	8	infer	infer	VB
cord-024061-gxv8y146	167	9	H5N1	H5N1	NNP
cord-024061-gxv8y146	167	10	avian	avian	JJ
cord-024061-gxv8y146	167	11	influenza	influenza	NN
cord-024061-gxv8y146	167	12	virus	virus	NN
cord-024061-gxv8y146	167	13	's	's	POS
cord-024061-gxv8y146	167	14	global	global	JJ
cord-024061-gxv8y146	167	15	origins	origin	NNS
cord-024061-gxv8y146	167	16	and	and	CC
cord-024061-gxv8y146	167	17	movements	movement	NNS
cord-024061-gxv8y146	167	18	between	between	IN
cord-024061-gxv8y146	167	19	countries	country	NNS
cord-024061-gxv8y146	167	20	.	.	.
cord-024061-gxv8y146	168	1	They	-PRON-	PRP
cord-024061-gxv8y146	168	2	used	use	VBD
cord-024061-gxv8y146	168	3	countries	country	NNS
cord-024061-gxv8y146	168	4	from	from	IN
cord-024061-gxv8y146	168	5	which	which	WDT
cord-024061-gxv8y146	168	6	the	the	DT
cord-024061-gxv8y146	168	7	sequences	sequence	NNS
cord-024061-gxv8y146	168	8	have	have	VBP
cord-024061-gxv8y146	168	9	been	be	VBN
cord-024061-gxv8y146	168	10	sampled	sample	VBN
cord-024061-gxv8y146	168	11	as	as	IN
cord-024061-gxv8y146	168	12	discrete	discrete	JJ
cord-024061-gxv8y146	168	13	traits	trait	NNS
cord-024061-gxv8y146	168	14	to	to	TO
cord-024061-gxv8y146	168	15	estimate	estimate	VB
cord-024061-gxv8y146	168	16	migration	migration	NN
cord-024061-gxv8y146	168	17	rates	rate	NNS
cord-024061-gxv8y146	168	18	between	between	IN
cord-024061-gxv8y146	168	19	pairs	pair	NNS
cord-024061-gxv8y146	168	20	of	of	IN
cord-024061-gxv8y146	168	21	predefined	predefined	JJ
cord-024061-gxv8y146	168	22	sets	set	NNS
cord-024061-gxv8y146	168	23	of	of	IN
cord-024061-gxv8y146	168	24	geographical	geographical	JJ
cord-024061-gxv8y146	168	25	locations	location	NNS
cord-024061-gxv8y146	168	26	,	,	,
cord-024061-gxv8y146	168	27	and	and	CC
cord-024061-gxv8y146	168	28	therefore	therefore	RB
cord-024061-gxv8y146	168	29	,	,	,
cord-024061-gxv8y146	168	30	the	the	DT
cord-024061-gxv8y146	168	31	method	method	NN
cord-024061-gxv8y146	168	32	is	be	VBZ
cord-024061-gxv8y146	168	33	named	name	VBN
cord-024061-gxv8y146	168	34	discrete	discrete	JJ
cord-024061-gxv8y146	168	35	phylogeography	phylogeography	NN
cord-024061-gxv8y146	168	36	(	(	-LRB-
cord-024061-gxv8y146	168	37	97	97	CD
cord-024061-gxv8y146	168	38	)	)	-RRB-
cord-024061-gxv8y146	168	39	.	.	.
cord-024061-gxv8y146	169	1	Also	also	RB
cord-024061-gxv8y146	169	2	,	,	,
cord-024061-gxv8y146	169	3	the	the	DT
cord-024061-gxv8y146	169	4	method	method	NN
cord-024061-gxv8y146	169	5	is	be	VBZ
cord-024061-gxv8y146	169	6	known	know	VBN
cord-024061-gxv8y146	169	7	as	as	IN
cord-024061-gxv8y146	169	8	discrete	discrete	JJ
cord-024061-gxv8y146	169	9	trait	trait	NN
cord-024061-gxv8y146	169	10	analysis	analysis	NN
cord-024061-gxv8y146	169	11	(	(	-LRB-
cord-024061-gxv8y146	169	12	DTA	DTA	NNP
cord-024061-gxv8y146	169	13	)	)	-RRB-
cord-024061-gxv8y146	169	14	because	because	IN
cord-024061-gxv8y146	169	15	it	-PRON-	PRP
cord-024061-gxv8y146	169	16	has	have	VBZ
cord-024061-gxv8y146	169	17	the	the	DT
cord-024061-gxv8y146	169	18	flexibility	flexibility	NN
cord-024061-gxv8y146	169	19	to	to	TO
cord-024061-gxv8y146	169	20	use	use	VB
cord-024061-gxv8y146	169	21	any	any	DT
cord-024061-gxv8y146	169	22	other	other	JJ
cord-024061-gxv8y146	169	23	discrete	discrete	JJ
cord-024061-gxv8y146	169	24	trait	trait	NN
cord-024061-gxv8y146	169	25	such	such	JJ
cord-024061-gxv8y146	169	26	as	as	IN
cord-024061-gxv8y146	169	27	host	host	NN
cord-024061-gxv8y146	169	28	or	or	CC
cord-024061-gxv8y146	169	29	farm	farm	NN
cord-024061-gxv8y146	169	30	characteristics	characteristic	NNS
cord-024061-gxv8y146	169	31	from	from	IN
cord-024061-gxv8y146	169	32	which	which	WDT
cord-024061-gxv8y146	169	33	the	the	DT
cord-024061-gxv8y146	169	34	sequences	sequence	NNS
cord-024061-gxv8y146	169	35	have	have	VBP
cord-024061-gxv8y146	169	36	been	be	VBN
cord-024061-gxv8y146	169	37	isolated	isolate	VBN
cord-024061-gxv8y146	169	38	to	to	TO
cord-024061-gxv8y146	169	39	model	model	VB
cord-024061-gxv8y146	169	40	migration	migration	NN
cord-024061-gxv8y146	169	41	rates	rate	NNS
cord-024061-gxv8y146	169	42	between	between	IN
cord-024061-gxv8y146	169	43	infected	infected	JJ
cord-024061-gxv8y146	169	44	hosts	host	NNS
cord-024061-gxv8y146	169	45	and	and	CC
cord-024061-gxv8y146	169	46	farms	farm	NNS
cord-024061-gxv8y146	169	47	(	(	-LRB-
cord-024061-gxv8y146	169	48	37	37	CD
cord-024061-gxv8y146	169	49	,	,	,
cord-024061-gxv8y146	169	50	98	98	CD
cord-024061-gxv8y146	169	51	)	)	-RRB-
cord-024061-gxv8y146	169	52	.	.	.
cord-024061-gxv8y146	170	1	Besides	besides	RB
cord-024061-gxv8y146	170	2	,	,	,
cord-024061-gxv8y146	170	3	the	the	DT
cord-024061-gxv8y146	170	4	method	method	NN
cord-024061-gxv8y146	170	5	can	can	MD
cord-024061-gxv8y146	170	6	infer	infer	VB
cord-024061-gxv8y146	170	7	ancestral	ancestral	JJ
cord-024061-gxv8y146	170	8	origins	origin	NNS
cord-024061-gxv8y146	170	9	(	(	-LRB-
cord-024061-gxv8y146	170	10	i.e.	i.e.	FW
cord-024061-gxv8y146	170	11	,	,	,
cord-024061-gxv8y146	170	12	from	from	IN
cord-024061-gxv8y146	170	13	the	the	DT
cord-024061-gxv8y146	170	14	assigned	assign	VBN
cord-024061-gxv8y146	170	15	discrete	discrete	JJ
cord-024061-gxv8y146	170	16	traits	trait	NNS
cord-024061-gxv8y146	170	17	)	)	-RRB-
cord-024061-gxv8y146	170	18	for	for	IN
cord-024061-gxv8y146	170	19	the	the	DT
cord-024061-gxv8y146	170	20	internal	internal	JJ
cord-024061-gxv8y146	170	21	nodes	node	NNS
cord-024061-gxv8y146	170	22	of	of	IN
cord-024061-gxv8y146	170	23	the	the	DT
cord-024061-gxv8y146	170	24	phylogeny	phylogeny	NN
cord-024061-gxv8y146	170	25	through	through	IN
cord-024061-gxv8y146	170	26	their	-PRON-	PRP$
cord-024061-gxv8y146	170	27	estimated	estimate	VBN
cord-024061-gxv8y146	170	28	root	root	NN
cord-024061-gxv8y146	170	29	state	state	NN
cord-024061-gxv8y146	170	30	posterior	posterior	JJ
cord-024061-gxv8y146	170	31	probabilities	probability	NNS
cord-024061-gxv8y146	170	32	(	(	-LRB-
cord-024061-gxv8y146	170	33	RSPP	RSPP	NNP
cord-024061-gxv8y146	170	34	)	)	-RRB-
cord-024061-gxv8y146	170	35	(	(	-LRB-
cord-024061-gxv8y146	170	36	97	97	CD
cord-024061-gxv8y146	170	37	)	)	-RRB-
cord-024061-gxv8y146	170	38	.	.	.
cord-024061-gxv8y146	171	1	However	however	RB
cord-024061-gxv8y146	171	2	,	,	,
cord-024061-gxv8y146	171	3	the	the	DT
cord-024061-gxv8y146	171	4	most	most	RBS
cord-024061-gxv8y146	171	5	notable	notable	JJ
cord-024061-gxv8y146	171	6	feature	feature	NN
cord-024061-gxv8y146	171	7	of	of	IN
cord-024061-gxv8y146	171	8	discrete	discrete	JJ
cord-024061-gxv8y146	171	9	phylogeographic	phylogeographic	JJ
cord-024061-gxv8y146	171	10	models	model	NNS
cord-024061-gxv8y146	171	11	is	be	VBZ
cord-024061-gxv8y146	171	12	the	the	DT
cord-024061-gxv8y146	171	13	integration	integration	NN
cord-024061-gxv8y146	171	14	of	of	IN
cord-024061-gxv8y146	171	15	a	a	DT
cord-024061-gxv8y146	171	16	Bayesian	bayesian	JJ
cord-024061-gxv8y146	171	17	stochastic	stochastic	JJ
cord-024061-gxv8y146	171	18	search	search	NN
cord-024061-gxv8y146	171	19	variable	variable	NN
cord-024061-gxv8y146	171	20	selection	selection	NN
cord-024061-gxv8y146	171	21	(	(	-LRB-
cord-024061-gxv8y146	171	22	BSSVS	BSSVS	NNP
cord-024061-gxv8y146	171	23	)	)	-RRB-
cord-024061-gxv8y146	171	24	procedure	procedure	NN
cord-024061-gxv8y146	171	25	to	to	TO
cord-024061-gxv8y146	171	26	identify	identify	VB
cord-024061-gxv8y146	171	27	significant	significant	JJ
cord-024061-gxv8y146	171	28	viral	viral	JJ
cord-024061-gxv8y146	171	29	dispersal	dispersal	NN
cord-024061-gxv8y146	171	30	routes	route	NNS
cord-024061-gxv8y146	171	31	between	between	IN
cord-024061-gxv8y146	171	32	geographical	geographical	JJ
cord-024061-gxv8y146	171	33	regions	region	NNS
cord-024061-gxv8y146	171	34	or	or	CC
cord-024061-gxv8y146	171	35	host	host	NN
cord-024061-gxv8y146	171	36	species	specie	NNS
cord-024061-gxv8y146	171	37	(	(	-LRB-
cord-024061-gxv8y146	171	38	97	97	CD
cord-024061-gxv8y146	171	39	)	)	-RRB-
cord-024061-gxv8y146	171	40	.	.	.
cord-024061-gxv8y146	172	1	BSSVS	BSSVS	NNP
cord-024061-gxv8y146	172	2	can	can	MD
cord-024061-gxv8y146	172	3	also	also	RB
cord-024061-gxv8y146	172	4	infer	infer	VB
cord-024061-gxv8y146	172	5	the	the	DT
cord-024061-gxv8y146	172	6	significance	significance	NN
cord-024061-gxv8y146	172	7	of	of	IN
cord-024061-gxv8y146	172	8	the	the	DT
cord-024061-gxv8y146	172	9	directionality	directionality	NN
cord-024061-gxv8y146	172	10	in	in	IN
cord-024061-gxv8y146	172	11	the	the	DT
cord-024061-gxv8y146	172	12	migration	migration	NN
cord-024061-gxv8y146	172	13	process	process	NN
cord-024061-gxv8y146	172	14	between	between	IN
cord-024061-gxv8y146	172	15	pairs	pair	NNS
cord-024061-gxv8y146	172	16	of	of	IN
cord-024061-gxv8y146	172	17	discrete	discrete	JJ
cord-024061-gxv8y146	172	18	traits	trait	NNS
cord-024061-gxv8y146	172	19	through	through	IN
cord-024061-gxv8y146	172	20	integrated	integrate	VBN
cord-024061-gxv8y146	172	21	symmetric	symmetric	JJ
cord-024061-gxv8y146	172	22	and	and	CC
cord-024061-gxv8y146	172	23	asymmetric	asymmetric	JJ
cord-024061-gxv8y146	172	24	substitution	substitution	NN
cord-024061-gxv8y146	172	25	models	model	NNS
cord-024061-gxv8y146	172	26	.	.	.
cord-024061-gxv8y146	173	1	The	the	DT
cord-024061-gxv8y146	173	2	symmetric	symmetric	JJ
cord-024061-gxv8y146	173	3	(	(	-LRB-
cord-024061-gxv8y146	173	4	Sym	Sym	NNP
cord-024061-gxv8y146	173	5	)	)	-RRB-
cord-024061-gxv8y146	173	6	model	model	NN
cord-024061-gxv8y146	173	7	assumes	assume	VBZ
cord-024061-gxv8y146	173	8	that	that	IN
cord-024061-gxv8y146	173	9	the	the	DT
cord-024061-gxv8y146	173	10	transition	transition	NN
cord-024061-gxv8y146	173	11	rate	rate	NN
cord-024061-gxv8y146	173	12	from	from	IN
cord-024061-gxv8y146	173	13	state	state	NN
cord-024061-gxv8y146	173	14	"	"	``
cord-024061-gxv8y146	173	15	A	a	NN
cord-024061-gxv8y146	173	16	"	"	''
cord-024061-gxv8y146	173	17	to	to	TO
cord-024061-gxv8y146	173	18	"	"	``
cord-024061-gxv8y146	173	19	B	b	NN
cord-024061-gxv8y146	173	20	"	"	''
cord-024061-gxv8y146	173	21	is	be	VBZ
cord-024061-gxv8y146	173	22	the	the	DT
cord-024061-gxv8y146	173	23	same	same	JJ
cord-024061-gxv8y146	173	24	as	as	IN
cord-024061-gxv8y146	173	25	the	the	DT
cord-024061-gxv8y146	173	26	transition	transition	NN
cord-024061-gxv8y146	173	27	rate	rate	NN
cord-024061-gxv8y146	173	28	from	from	IN
cord-024061-gxv8y146	173	29	state	state	NN
cord-024061-gxv8y146	173	30	"	"	``
cord-024061-gxv8y146	173	31	B	b	NN
cord-024061-gxv8y146	173	32	"	"	''
cord-024061-gxv8y146	173	33	to	to	IN
cord-024061-gxv8y146	173	34	"	"	``
cord-024061-gxv8y146	173	35	A	a	NN
cord-024061-gxv8y146	173	36	"	"	''
cord-024061-gxv8y146	173	37	(	(	-LRB-
cord-024061-gxv8y146	173	38	i.e.	i.e.	FW
cord-024061-gxv8y146	173	39	,	,	,
cord-024061-gxv8y146	173	40	directional	directional	JJ
cord-024061-gxv8y146	173	41	spread	spread	NN
cord-024061-gxv8y146	173	42	between	between	IN
cord-024061-gxv8y146	173	43	traits	trait	NNS
cord-024061-gxv8y146	173	44	is	be	VBZ
cord-024061-gxv8y146	173	45	insignificant	insignificant	JJ
cord-024061-gxv8y146	173	46	)	)	-RRB-
cord-024061-gxv8y146	173	47	,	,	,
cord-024061-gxv8y146	173	48	while	while	IN
cord-024061-gxv8y146	173	49	the	the	DT
cord-024061-gxv8y146	173	50	asymmetric	asymmetric	JJ
cord-024061-gxv8y146	173	51	(	(	-LRB-
cord-024061-gxv8y146	173	52	Asym	Asym	NNP
cord-024061-gxv8y146	173	53	)	)	-RRB-
cord-024061-gxv8y146	173	54	model	model	NN
cord-024061-gxv8y146	173	55	assumes	assume	VBZ
cord-024061-gxv8y146	173	56	that	that	IN
cord-024061-gxv8y146	173	57	the	the	DT
cord-024061-gxv8y146	173	58	transition	transition	NN
cord-024061-gxv8y146	173	59	rate	rate	NN
cord-024061-gxv8y146	173	60	from	from	IN
cord-024061-gxv8y146	173	61	state	state	NN
cord-024061-gxv8y146	173	62	"	"	``
cord-024061-gxv8y146	173	63	A	a	NN
cord-024061-gxv8y146	173	64	"	"	''
cord-024061-gxv8y146	173	65	to	to	TO
cord-024061-gxv8y146	173	66	"	"	``
cord-024061-gxv8y146	173	67	B	b	NN
cord-024061-gxv8y146	173	68	"	"	''
cord-024061-gxv8y146	173	69	is	be	VBZ
cord-024061-gxv8y146	173	70	different	different	JJ
cord-024061-gxv8y146	173	71	from	from	IN
cord-024061-gxv8y146	173	72	the	the	DT
cord-024061-gxv8y146	173	73	transition	transition	NN
cord-024061-gxv8y146	173	74	rate	rate	NN
cord-024061-gxv8y146	173	75	from	from	IN
cord-024061-gxv8y146	173	76	state	state	NN
cord-024061-gxv8y146	173	77	"	"	``
cord-024061-gxv8y146	173	78	B	b	NN
cord-024061-gxv8y146	173	79	"	"	''
cord-024061-gxv8y146	173	80	to	to	IN
cord-024061-gxv8y146	173	81	"	"	``
cord-024061-gxv8y146	173	82	A	a	NN
cord-024061-gxv8y146	173	83	"	"	''
cord-024061-gxv8y146	173	84	(	(	-LRB-
cord-024061-gxv8y146	173	85	i.e.	i.e.	FW
cord-024061-gxv8y146	173	86	,	,	,
cord-024061-gxv8y146	173	87	directional	directional	JJ
cord-024061-gxv8y146	173	88	spread	spread	NN
cord-024061-gxv8y146	173	89	between	between	IN
cord-024061-gxv8y146	173	90	traits	trait	NNS
cord-024061-gxv8y146	173	91	is	be	VBZ
cord-024061-gxv8y146	173	92	significant	significant	JJ
cord-024061-gxv8y146	173	93	)	)	-RRB-
cord-024061-gxv8y146	173	94	(	(	-LRB-
cord-024061-gxv8y146	173	95	97	97	CD
cord-024061-gxv8y146	173	96	)	)	-RRB-
cord-024061-gxv8y146	173	97	.	.	.
cord-024061-gxv8y146	174	1	However	however	RB
cord-024061-gxv8y146	174	2	,	,	,
cord-024061-gxv8y146	174	3	the	the	DT
cord-024061-gxv8y146	174	4	lack	lack	NN
cord-024061-gxv8y146	174	5	of	of	IN
cord-024061-gxv8y146	174	6	a	a	DT
cord-024061-gxv8y146	174	7	sufficient	sufficient	JJ
cord-024061-gxv8y146	174	8	number	number	NN
cord-024061-gxv8y146	174	9	of	of	IN
cord-024061-gxv8y146	174	10	sequences	sequence	NNS
cord-024061-gxv8y146	174	11	closer	close	RBR
cord-024061-gxv8y146	174	12	to	to	IN
cord-024061-gxv8y146	174	13	the	the	DT
cord-024061-gxv8y146	174	14	root	root	NN
cord-024061-gxv8y146	174	15	of	of	IN
cord-024061-gxv8y146	174	16	the	the	DT
cord-024061-gxv8y146	174	17	phylogeny	phylogeny	NN
cord-024061-gxv8y146	174	18	can	can	MD
cord-024061-gxv8y146	174	19	impact	impact	VB
cord-024061-gxv8y146	174	20	accurate	accurate	JJ
cord-024061-gxv8y146	174	21	estimation	estimation	NN
cord-024061-gxv8y146	174	22	of	of	IN
cord-024061-gxv8y146	174	23	ancestral	ancestral	JJ
cord-024061-gxv8y146	174	24	traits	trait	NNS
cord-024061-gxv8y146	174	25	(	(	-LRB-
cord-024061-gxv8y146	174	26	i.e.	i.e.	FW
cord-024061-gxv8y146	174	27	,	,	,
cord-024061-gxv8y146	174	28	ancestral	ancestral	JJ
cord-024061-gxv8y146	174	29	geographical	geographical	JJ
cord-024061-gxv8y146	174	30	location	location	NN
cord-024061-gxv8y146	174	31	or	or	CC
cord-024061-gxv8y146	174	32	host	host	NN
cord-024061-gxv8y146	174	33	)	)	-RRB-
cord-024061-gxv8y146	174	34	by	by	IN
cord-024061-gxv8y146	174	35	the	the	DT
cord-024061-gxv8y146	174	36	DTA	DTA	NNP
cord-024061-gxv8y146	174	37	method	method	NN
cord-024061-gxv8y146	174	38	(	(	-LRB-
cord-024061-gxv8y146	174	39	97	97	CD
cord-024061-gxv8y146	174	40	)	)	-RRB-
cord-024061-gxv8y146	174	41	.	.	.
cord-024061-gxv8y146	175	1	Therefore	therefore	RB
cord-024061-gxv8y146	175	2	,	,	,
cord-024061-gxv8y146	175	3	DTA	DTA	NNP
cord-024061-gxv8y146	175	4	robustness	robustness	NN
cord-024061-gxv8y146	175	5	can	can	MD
cord-024061-gxv8y146	175	6	be	be	VB
cord-024061-gxv8y146	175	7	improved	improve	VBN
cord-024061-gxv8y146	175	8	by	by	IN
cord-024061-gxv8y146	175	9	increasing	increase	VBG
cord-024061-gxv8y146	175	10	the	the	DT
cord-024061-gxv8y146	175	11	geographical	geographical	JJ
cord-024061-gxv8y146	175	12	density	density	NN
cord-024061-gxv8y146	175	13	and	and	CC
cord-024061-gxv8y146	175	14	temporal	temporal	JJ
cord-024061-gxv8y146	175	15	depth	depth	NN
cord-024061-gxv8y146	175	16	of	of	IN
cord-024061-gxv8y146	175	17	sampling	sampling	NN
cord-024061-gxv8y146	175	18	(	(	-LRB-
cord-024061-gxv8y146	175	19	96	96	CD
cord-024061-gxv8y146	175	20	)	)	-RRB-
cord-024061-gxv8y146	175	21	.	.	.
cord-024061-gxv8y146	176	1	DTA	DTA	NNP
cord-024061-gxv8y146	176	2	is	be	VBZ
cord-024061-gxv8y146	176	3	also	also	RB
cord-024061-gxv8y146	176	4	limited	limit	VBN
cord-024061-gxv8y146	176	5	by	by	IN
cord-024061-gxv8y146	176	6	the	the	DT
cord-024061-gxv8y146	176	7	type	type	NN
cord-024061-gxv8y146	176	8	and	and	CC
cord-024061-gxv8y146	176	9	number	number	NN
cord-024061-gxv8y146	176	10	of	of	IN
cord-024061-gxv8y146	176	11	variables	variable	NNS
cord-024061-gxv8y146	176	12	that	that	WDT
cord-024061-gxv8y146	176	13	can	can	MD
cord-024061-gxv8y146	176	14	be	be	VB
cord-024061-gxv8y146	176	15	used	use	VBN
cord-024061-gxv8y146	176	16	to	to	TO
cord-024061-gxv8y146	176	17	estimate	estimate	VB
cord-024061-gxv8y146	176	18	ancestral	ancestral	JJ
cord-024061-gxv8y146	176	19	states	state	NNS
cord-024061-gxv8y146	176	20	.	.	.
cord-024061-gxv8y146	177	1	Therefore	therefore	RB
cord-024061-gxv8y146	177	2	,	,	,
cord-024061-gxv8y146	177	3	the	the	DT
cord-024061-gxv8y146	177	4	BSSVS	BSSVS	NNP
cord-024061-gxv8y146	177	5	framework	framework	NN
cord-024061-gxv8y146	177	6	has	have	VBZ
cord-024061-gxv8y146	177	7	been	be	VBN
cord-024061-gxv8y146	177	8	extended	extend	VBN
cord-024061-gxv8y146	177	9	to	to	TO
cord-024061-gxv8y146	177	10	accommodate	accommodate	VB
cord-024061-gxv8y146	177	11	a	a	DT
cord-024061-gxv8y146	177	12	transitional	transitional	JJ
cord-024061-gxv8y146	177	13	rate	rate	NN
cord-024061-gxv8y146	177	14	matrix	matrix	NN
cord-024061-gxv8y146	177	15	between	between	IN
cord-024061-gxv8y146	177	16	discrete	discrete	JJ
cord-024061-gxv8y146	177	17	traits	trait	NNS
cord-024061-gxv8y146	177	18	as	as	IN
cord-024061-gxv8y146	177	19	a	a	DT
cord-024061-gxv8y146	177	20	generalized	generalized	JJ
cord-024061-gxv8y146	177	21	linear	linear	JJ
cord-024061-gxv8y146	177	22	model	model	NN
cord-024061-gxv8y146	177	23	(	(	-LRB-
cord-024061-gxv8y146	177	24	GLM	GLM	NNP
cord-024061-gxv8y146	177	25	)	)	-RRB-
cord-024061-gxv8y146	177	26	(	(	-LRB-
cord-024061-gxv8y146	177	27	22	22	CD
cord-024061-gxv8y146	177	28	,	,	,
cord-024061-gxv8y146	177	29	32	32	CD
cord-024061-gxv8y146	177	30	)	)	-RRB-
cord-024061-gxv8y146	177	31	.	.	.
cord-024061-gxv8y146	178	1	The	the	DT
cord-024061-gxv8y146	178	2	method	method	NN
cord-024061-gxv8y146	178	3	improves	improve	VBZ
cord-024061-gxv8y146	178	4	biological	biological	JJ
cord-024061-gxv8y146	178	5	plausibility	plausibility	NN
cord-024061-gxv8y146	178	6	of	of	IN
cord-024061-gxv8y146	178	7	the	the	DT
cord-024061-gxv8y146	178	8	inferred	infer	VBN
cord-024061-gxv8y146	178	9	RSPP	RSPP	NNP
cord-024061-gxv8y146	178	10	for	for	IN
cord-024061-gxv8y146	178	11	the	the	DT
cord-024061-gxv8y146	178	12	ancestral	ancestral	JJ
cord-024061-gxv8y146	178	13	traitsby	traitsby	NN
cord-024061-gxv8y146	178	14	simultaneously	simultaneously	RB
cord-024061-gxv8y146	178	15	estimating	estimate	VBG
cord-024061-gxv8y146	178	16	the	the	DT
cord-024061-gxv8y146	178	17	inclusion	inclusion	NN
cord-024061-gxv8y146	178	18	probabilities	probability	NNS
cord-024061-gxv8y146	178	19	of	of	IN
cord-024061-gxv8y146	178	20	geographic	geographic	JJ
cord-024061-gxv8y146	178	21	,	,	,
cord-024061-gxv8y146	178	22	demographic	demographic	JJ
cord-024061-gxv8y146	178	23	,	,	,
cord-024061-gxv8y146	178	24	and	and	CC
cord-024061-gxv8y146	178	25	environmental	environmental	JJ
cord-024061-gxv8y146	178	26	predictors	predictor	NNS
cord-024061-gxv8y146	178	27	(	(	-LRB-
cord-024061-gxv8y146	178	28	22	22	CD
cord-024061-gxv8y146	178	29	)	)	-RRB-
cord-024061-gxv8y146	178	30	.	.	.
cord-024061-gxv8y146	179	1	However	however	RB
cord-024061-gxv8y146	179	2	,	,	,
cord-024061-gxv8y146	179	3	the	the	DT
cord-024061-gxv8y146	179	4	method	method	NN
cord-024061-gxv8y146	179	5	is	be	VBZ
cord-024061-gxv8y146	179	6	shown	show	VBN
cord-024061-gxv8y146	179	7	to	to	TO
cord-024061-gxv8y146	179	8	be	be	VB
cord-024061-gxv8y146	179	9	more	more	RBR
cord-024061-gxv8y146	179	10	sensitive	sensitive	JJ
cord-024061-gxv8y146	179	11	to	to	IN
cord-024061-gxv8y146	179	12	sampling	sampling	NN
cord-024061-gxv8y146	179	13	bias	bias	NN
cord-024061-gxv8y146	179	14	than	than	IN
cord-024061-gxv8y146	179	15	the	the	DT
cord-024061-gxv8y146	179	16	standard	standard	JJ
cord-024061-gxv8y146	179	17	BSSVS	BSSVS	NNP
cord-024061-gxv8y146	179	18	approach	approach	NN
cord-024061-gxv8y146	179	19	(	(	-LRB-
cord-024061-gxv8y146	179	20	32	32	CD
cord-024061-gxv8y146	179	21	)	)	-RRB-
cord-024061-gxv8y146	179	22	.	.	.
cord-024061-gxv8y146	180	1	Hence	hence	RB
cord-024061-gxv8y146	180	2	,	,	,
cord-024061-gxv8y146	180	3	comparative	comparative	JJ
cord-024061-gxv8y146	180	4	sensitivity	sensitivity	NN
cord-024061-gxv8y146	180	5	analyses	analysis	NNS
cord-024061-gxv8y146	180	6	to	to	IN
cord-024061-gxv8y146	180	7	sampling	sampling	NN
cord-024061-gxv8y146	180	8	bias	bias	NN
cord-024061-gxv8y146	180	9	between	between	IN
cord-024061-gxv8y146	180	10	the	the	DT
cord-024061-gxv8y146	180	11	approaches	approach	NNS
cord-024061-gxv8y146	180	12	are	be	VBP
cord-024061-gxv8y146	180	13	recommended	recommend	VBN
cord-024061-gxv8y146	180	14	to	to	TO
cord-024061-gxv8y146	180	15	avoid	avoid	VB
cord-024061-gxv8y146	180	16	severely	severely	RB
cord-024061-gxv8y146	180	17	biased	biased	JJ
cord-024061-gxv8y146	180	18	inferred	infer	VBN
cord-024061-gxv8y146	180	19	RSPPs	rspp	NNS
cord-024061-gxv8y146	180	20	.	.	.
cord-024061-gxv8y146	181	1	In	in	IN
cord-024061-gxv8y146	181	2	some	some	DT
cord-024061-gxv8y146	181	3	settings	setting	NNS
cord-024061-gxv8y146	181	4	,	,	,
cord-024061-gxv8y146	181	5	geographical	geographical	JJ
cord-024061-gxv8y146	181	6	boundaries	boundary	NNS
cord-024061-gxv8y146	181	7	can	can	MD
cord-024061-gxv8y146	181	8	not	not	RB
cord-024061-gxv8y146	181	9	be	be	VB
cord-024061-gxv8y146	181	10	defined	define	VBN
cord-024061-gxv8y146	181	11	by	by	IN
cord-024061-gxv8y146	181	12	discrete	discrete	JJ
cord-024061-gxv8y146	181	13	spatial	spatial	JJ
cord-024061-gxv8y146	181	14	traits	trait	NNS
cord-024061-gxv8y146	181	15	such	such	JJ
cord-024061-gxv8y146	181	16	as	as	IN
cord-024061-gxv8y146	181	17	the	the	DT
cord-024061-gxv8y146	181	18	distribution	distribution	NN
cord-024061-gxv8y146	181	19	of	of	IN
cord-024061-gxv8y146	181	20	wildlife	wildlife	NN
cord-024061-gxv8y146	181	21	hosts	host	NNS
cord-024061-gxv8y146	181	22	or	or	CC
cord-024061-gxv8y146	181	23	disease	disease	NN
cord-024061-gxv8y146	181	24	vectors	vector	NNS
cord-024061-gxv8y146	181	25	and	and	CC
cord-024061-gxv8y146	181	26	,	,	,
cord-024061-gxv8y146	181	27	therefore	therefore	RB
cord-024061-gxv8y146	181	28	,	,	,
cord-024061-gxv8y146	181	29	viral	viral	JJ
cord-024061-gxv8y146	181	30	evolution	evolution	NN
cord-024061-gxv8y146	181	31	and	and	CC
cord-024061-gxv8y146	181	32	spread	spread	VB
cord-024061-gxv8y146	181	33	better	well	RBR
cord-024061-gxv8y146	181	34	modeled	model	VBN
cord-024061-gxv8y146	181	35	by	by	IN
cord-024061-gxv8y146	181	36	continuous	continuous	JJ
cord-024061-gxv8y146	181	37	spatial	spatial	JJ
cord-024061-gxv8y146	181	38	diffusion	diffusion	NN
cord-024061-gxv8y146	181	39	models	model	NNS
cord-024061-gxv8y146	181	40	(	(	-LRB-
cord-024061-gxv8y146	181	41	96	96	CD
cord-024061-gxv8y146	181	42	)	)	-RRB-
cord-024061-gxv8y146	181	43	.	.	.
cord-024061-gxv8y146	182	1	When	when	WRB
cord-024061-gxv8y146	182	2	precise	precise	JJ
cord-024061-gxv8y146	182	3	geographical	geographical	JJ
cord-024061-gxv8y146	182	4	information	information	NN
cord-024061-gxv8y146	182	5	is	be	VBZ
cord-024061-gxv8y146	182	6	available	available	JJ
cord-024061-gxv8y146	182	7	(	(	-LRB-
cord-024061-gxv8y146	182	8	i.e.	i.e.	FW
cord-024061-gxv8y146	182	9	,	,	,
cord-024061-gxv8y146	182	10	longitude	longitude	NN
cord-024061-gxv8y146	182	11	and	and	CC
cord-024061-gxv8y146	182	12	latitude	latitude	NN
cord-024061-gxv8y146	182	13	)	)	-RRB-
cord-024061-gxv8y146	182	14	,	,	,
cord-024061-gxv8y146	182	15	continuous	continuous	JJ
cord-024061-gxv8y146	182	16	phylogeographic	phylogeographic	NNP
cord-024061-gxv8y146	182	17	can	can	MD
cord-024061-gxv8y146	182	18	reconstruct	reconstruct	VB
cord-024061-gxv8y146	182	19	the	the	DT
cord-024061-gxv8y146	182	20	viral	viral	JJ
cord-024061-gxv8y146	182	21	spatio	spatio	JJ
cord-024061-gxv8y146	182	22	-	-	HYPH
cord-024061-gxv8y146	182	23	temporal	temporal	JJ
cord-024061-gxv8y146	182	24	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	182	25	history	history	NN
cord-024061-gxv8y146	182	26	using	use	VBG
cord-024061-gxv8y146	182	27	relaxed	relaxed	JJ
cord-024061-gxv8y146	182	28	random	random	JJ
cord-024061-gxv8y146	182	29	walk	walk	NN
cord-024061-gxv8y146	182	30	models	model	NNS
cord-024061-gxv8y146	182	31	(	(	-LRB-
cord-024061-gxv8y146	182	32	19	19	CD
cord-024061-gxv8y146	182	33	)	)	-RRB-
cord-024061-gxv8y146	182	34	.	.	.
cord-024061-gxv8y146	183	1	These	these	DT
cord-024061-gxv8y146	183	2	models	model	NNS
cord-024061-gxv8y146	183	3	can	can	MD
cord-024061-gxv8y146	183	4	additionally	additionally	RB
cord-024061-gxv8y146	183	5	estimate	estimate	VB
cord-024061-gxv8y146	183	6	viral	viral	JJ
cord-024061-gxv8y146	183	7	dispersal	dispersal	NN
cord-024061-gxv8y146	183	8	rate	rate	NN
cord-024061-gxv8y146	183	9	in	in	IN
cord-024061-gxv8y146	183	10	km	km	NNP
cord-024061-gxv8y146	183	11	2	2	CD
cord-024061-gxv8y146	183	12	/year	/year	,
cord-024061-gxv8y146	183	13	and	and	CC
cord-024061-gxv8y146	183	14	can	can	MD
cord-024061-gxv8y146	183	15	distinguish	distinguish	VB
cord-024061-gxv8y146	183	16	whether	whether	IN
cord-024061-gxv8y146	183	17	the	the	DT
cord-024061-gxv8y146	183	18	spatial	spatial	JJ
cord-024061-gxv8y146	183	19	diffusion	diffusion	NN
cord-024061-gxv8y146	183	20	process	process	NN
cord-024061-gxv8y146	183	21	was	be	VBD
cord-024061-gxv8y146	183	22	homogenous	homogenous	JJ
cord-024061-gxv8y146	183	23	(	(	-LRB-
cord-024061-gxv8y146	183	24	e.g.	e.g.	RB
cord-024061-gxv8y146	183	25	,	,	,
cord-024061-gxv8y146	183	26	dispersal	dispersal	NN
cord-024061-gxv8y146	183	27	by	by	IN
cord-024061-gxv8y146	183	28	air	air	NN
cord-024061-gxv8y146	183	29	)	)	-RRB-
cord-024061-gxv8y146	183	30	or	or	CC
cord-024061-gxv8y146	183	31	heterogeneous	heterogeneous	JJ
cord-024061-gxv8y146	183	32	(	(	-LRB-
cord-024061-gxv8y146	183	33	dispersal	dispersal	NN
cord-024061-gxv8y146	183	34	by	by	IN
cord-024061-gxv8y146	183	35	movements	movement	NNS
cord-024061-gxv8y146	183	36	)	)	-RRB-
cord-024061-gxv8y146	183	37	(	(	-LRB-
cord-024061-gxv8y146	183	38	19	19	CD
cord-024061-gxv8y146	183	39	,	,	,
cord-024061-gxv8y146	183	40	21	21	CD
cord-024061-gxv8y146	183	41	)	)	-RRB-
cord-024061-gxv8y146	183	42	.	.	.
cord-024061-gxv8y146	184	1	In	in	IN
cord-024061-gxv8y146	184	2	many	many	JJ
cord-024061-gxv8y146	184	3	instances	instance	NNS
cord-024061-gxv8y146	184	4	,	,	,
cord-024061-gxv8y146	184	5	sequence	sequence	NN
cord-024061-gxv8y146	184	6	samples	sample	NNS
cord-024061-gxv8y146	184	7	tend	tend	VBP
cord-024061-gxv8y146	184	8	to	to	TO
cord-024061-gxv8y146	184	9	cluster	cluster	VB
cord-024061-gxv8y146	184	10	within	within	IN
cord-024061-gxv8y146	184	11	a	a	DT
cord-024061-gxv8y146	184	12	geographical	geographical	JJ
cord-024061-gxv8y146	184	13	region	region	NN
cord-024061-gxv8y146	184	14	leading	lead	VBG
cord-024061-gxv8y146	184	15	to	to	IN
cord-024061-gxv8y146	184	16	incomplete	incomplete	JJ
cord-024061-gxv8y146	184	17	mixing	mixing	NN
cord-024061-gxv8y146	184	18	and	and	CC
cord-024061-gxv8y146	184	19	formation	formation	NN
cord-024061-gxv8y146	184	20	of	of	IN
cord-024061-gxv8y146	184	21	structure	structure	NN
cord-024061-gxv8y146	184	22	in	in	IN
cord-024061-gxv8y146	184	23	the	the	DT
cord-024061-gxv8y146	184	24	population	population	NN
cord-024061-gxv8y146	184	25	.	.	.
cord-024061-gxv8y146	185	1	This	this	DT
cord-024061-gxv8y146	185	2	might	may	MD
cord-024061-gxv8y146	185	3	bias	bias	VB
cord-024061-gxv8y146	185	4	the	the	DT
cord-024061-gxv8y146	185	5	posterior	posterior	JJ
cord-024061-gxv8y146	185	6	inferences	inference	NNS
cord-024061-gxv8y146	185	7	that	that	WDT
cord-024061-gxv8y146	185	8	estimated	estimate	VBD
cord-024061-gxv8y146	185	9	the	the	DT
cord-024061-gxv8y146	185	10	coalescent	coalescent	JJ
cord-024061-gxv8y146	185	11	phylogeographic	phylogeographic	JJ
cord-024061-gxv8y146	185	12	models	model	NNS
cord-024061-gxv8y146	185	13	mentioned	mention	VBN
cord-024061-gxv8y146	185	14	above	above	RB
cord-024061-gxv8y146	185	15	.	.	.
cord-024061-gxv8y146	186	1	Hence	hence	RB
cord-024061-gxv8y146	186	2	,	,	,
cord-024061-gxv8y146	186	3	the	the	DT
cord-024061-gxv8y146	186	4	recently	recently	RB
cord-024061-gxv8y146	186	5	developed	develop	VBN
cord-024061-gxv8y146	186	6	structured	structured	JJ
cord-024061-gxv8y146	186	7	coalescent	coalescent	NN
cord-024061-gxv8y146	186	8	tree	tree	NN
cord-024061-gxv8y146	186	9	models	model	NNS
cord-024061-gxv8y146	186	10	for	for	IN
cord-024061-gxv8y146	186	11	inferring	infer	VBG
cord-024061-gxv8y146	186	12	phylogeography	phylogeography	NN
cord-024061-gxv8y146	186	13	can	can	MD
cord-024061-gxv8y146	186	14	simultaneously	simultaneously	RB
cord-024061-gxv8y146	186	15	model	model	VB
cord-024061-gxv8y146	186	16	the	the	DT
cord-024061-gxv8y146	186	17	migration	migration	NN
cord-024061-gxv8y146	186	18	process	process	NN
cord-024061-gxv8y146	186	19	between	between	IN
cord-024061-gxv8y146	186	20	regions	region	NNS
cord-024061-gxv8y146	186	21	while	while	IN
cord-024061-gxv8y146	186	22	allowing	allow	VBG
cord-024061-gxv8y146	186	23	for	for	IN
cord-024061-gxv8y146	186	24	those	those	DT
cord-024061-gxv8y146	186	25	regions	region	NNS
cord-024061-gxv8y146	186	26	to	to	TO
cord-024061-gxv8y146	186	27	have	have	VB
cord-024061-gxv8y146	186	28	their	-PRON-	PRP$
cord-024061-gxv8y146	186	29	unique	unique	JJ
cord-024061-gxv8y146	186	30	coalescent	coalescent	NN
cord-024061-gxv8y146	186	31	rates	rate	NNS
cord-024061-gxv8y146	186	32	(	(	-LRB-
cord-024061-gxv8y146	186	33	96	96	CD
cord-024061-gxv8y146	186	34	,	,	,
cord-024061-gxv8y146	186	35	99	99	CD
cord-024061-gxv8y146	186	36	)	)	-RRB-
cord-024061-gxv8y146	186	37	.	.	.
cord-024061-gxv8y146	187	1	Unlike	unlike	IN
cord-024061-gxv8y146	187	2	BEAST	BEAST	NNP
cord-024061-gxv8y146	187	3	1.X	1.x	CD
cord-024061-gxv8y146	187	4	,	,	,
cord-024061-gxv8y146	187	5	BEAST	BEAST	NNP
cord-024061-gxv8y146	187	6	2.X	2.x	CD
cord-024061-gxv8y146	187	7	has	have	VBZ
cord-024061-gxv8y146	187	8	recently	recently	RB
cord-024061-gxv8y146	187	9	implemented	implement	VBN
cord-024061-gxv8y146	187	10	several	several	JJ
cord-024061-gxv8y146	187	11	structured	structured	JJ
cord-024061-gxv8y146	187	12	coalescent	coalescent	NN
cord-024061-gxv8y146	187	13	models	model	NNS
cord-024061-gxv8y146	187	14	for	for	IN
cord-024061-gxv8y146	187	15	inferring	infer	VBG
cord-024061-gxv8y146	187	16	geographic	geographic	JJ
cord-024061-gxv8y146	187	17	and	and	CC
cord-024061-gxv8y146	187	18	between	between	IN
cord-024061-gxv8y146	187	19	-	-	HYPH
cord-024061-gxv8y146	187	20	host	host	NN
cord-024061-gxv8y146	187	21	transmission	transmission	NN
cord-024061-gxv8y146	187	22	histories	history	NNS
cord-024061-gxv8y146	187	23	,	,	,
cord-024061-gxv8y146	187	24	including	include	VBG
cord-024061-gxv8y146	187	25	Bayesian	bayesian	JJ
cord-024061-gxv8y146	187	26	structured	structured	JJ
cord-024061-gxv8y146	187	27	coalescent	coalescent	NN
cord-024061-gxv8y146	187	28	approximation	approximation	NN
cord-024061-gxv8y146	187	29	(	(	-LRB-
cord-024061-gxv8y146	187	30	BASTA	BASTA	NNP
cord-024061-gxv8y146	187	31	)	)	-RRB-
cord-024061-gxv8y146	187	32	(	(	-LRB-
cord-024061-gxv8y146	187	33	26	26	CD
cord-024061-gxv8y146	187	34	)	)	-RRB-
cord-024061-gxv8y146	187	35	,	,	,
cord-024061-gxv8y146	187	36	structured	structured	JJ
cord-024061-gxv8y146	187	37	coalescent	coalescent	NN
cord-024061-gxv8y146	187	38	transmission	transmission	NN
cord-024061-gxv8y146	187	39	tree	tree	NN
cord-024061-gxv8y146	187	40	inference	inference	NN
cord-024061-gxv8y146	187	41	(	(	-LRB-
cord-024061-gxv8y146	187	42	SCOTTI	SCOTTI	NNP
cord-024061-gxv8y146	187	43	)	)	-RRB-
cord-024061-gxv8y146	187	44	(	(	-LRB-
cord-024061-gxv8y146	187	45	100	100	CD
cord-024061-gxv8y146	187	46	)	)	-RRB-
cord-024061-gxv8y146	187	47	,	,	,
cord-024061-gxv8y146	187	48	and	and	CC
cord-024061-gxv8y146	187	49	marginal	marginal	JJ
cord-024061-gxv8y146	187	50	approximation	approximation	NN
cord-024061-gxv8y146	187	51	of	of	IN
cord-024061-gxv8y146	187	52	the	the	DT
cord-024061-gxv8y146	187	53	structured	structured	JJ
cord-024061-gxv8y146	187	54	coalescent	coalescent	NN
cord-024061-gxv8y146	187	55	(	(	-LRB-
cord-024061-gxv8y146	187	56	MASCOT	MASCOT	NNP
cord-024061-gxv8y146	187	57	)	)	-RRB-
cord-024061-gxv8y146	187	58	(	(	-LRB-
cord-024061-gxv8y146	187	59	101	101	CD
cord-024061-gxv8y146	187	60	)	)	-RRB-
cord-024061-gxv8y146	187	61	.	.	.
cord-024061-gxv8y146	188	1	The	the	DT
cord-024061-gxv8y146	188	2	complexity	complexity	NN
cord-024061-gxv8y146	188	3	of	of	IN
cord-024061-gxv8y146	188	4	infectious	infectious	JJ
cord-024061-gxv8y146	188	5	disease	disease	NN
cord-024061-gxv8y146	188	6	transmission	transmission	NN
cord-024061-gxv8y146	188	7	dynamics	dynamic	NNS
cord-024061-gxv8y146	188	8	pushed	push	VBD
cord-024061-gxv8y146	188	9	the	the	DT
cord-024061-gxv8y146	188	10	capacity	capacity	NN
cord-024061-gxv8y146	188	11	of	of	IN
cord-024061-gxv8y146	188	12	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	188	13	models	model	NNS
cord-024061-gxv8y146	188	14	beyond	beyond	IN
cord-024061-gxv8y146	188	15	demographic	demographic	JJ
cord-024061-gxv8y146	188	16	and	and	CC
cord-024061-gxv8y146	188	17	phylogeographic	phylogeographic	JJ
cord-024061-gxv8y146	188	18	reconstructions	reconstruction	NNS
cord-024061-gxv8y146	188	19	into	into	IN
cord-024061-gxv8y146	188	20	investigating	investigate	VBG
cord-024061-gxv8y146	188	21	traditional	traditional	JJ
cord-024061-gxv8y146	188	22	and	and	CC
cord-024061-gxv8y146	188	23	new	new	JJ
cord-024061-gxv8y146	188	24	epidemiological	epidemiological	JJ
cord-024061-gxv8y146	188	25	problems	problem	NNS
cord-024061-gxv8y146	188	26	.	.	.
cord-024061-gxv8y146	189	1	One	one	CD
cord-024061-gxv8y146	189	2	notable	notable	JJ
cord-024061-gxv8y146	189	3	example	example	NN
cord-024061-gxv8y146	189	4	was	be	VBD
cord-024061-gxv8y146	189	5	demonstrated	demonstrate	VBN
cord-024061-gxv8y146	189	6	by	by	IN
cord-024061-gxv8y146	189	7	Volz	Volz	NNP
cord-024061-gxv8y146	189	8	et	et	NNP
cord-024061-gxv8y146	189	9	al	al	NNP
cord-024061-gxv8y146	189	10	.	.	.
cord-024061-gxv8y146	190	1	by	by	IN
cord-024061-gxv8y146	190	2	developing	develop	VBG
cord-024061-gxv8y146	190	3	a	a	DT
cord-024061-gxv8y146	190	4	structured	structured	JJ
cord-024061-gxv8y146	190	5	coalescent	coalescent	NN
cord-024061-gxv8y146	190	6	susceptible	susceptible	JJ
cord-024061-gxv8y146	190	7	-	-	HYPH
cord-024061-gxv8y146	190	8	infected	infected	JJ
cord-024061-gxv8y146	190	9	-	-	HYPH
cord-024061-gxv8y146	190	10	recovered	recovered	JJ
cord-024061-gxv8y146	190	11	(	(	-LRB-
cord-024061-gxv8y146	190	12	SIR	SIR	NNP
cord-024061-gxv8y146	190	13	)	)	-RRB-
cord-024061-gxv8y146	190	14	model	model	NN
cord-024061-gxv8y146	190	15	to	to	TO
cord-024061-gxv8y146	190	16	infer	infer	VB
cord-024061-gxv8y146	190	17	reproductive	reproductive	JJ
cord-024061-gxv8y146	190	18	numbers	number	NNS
cord-024061-gxv8y146	190	19	from	from	IN
cord-024061-gxv8y146	190	20	viral	viral	JJ
cord-024061-gxv8y146	190	21	sequences	sequence	NNS
cord-024061-gxv8y146	190	22	data	data	NN
cord-024061-gxv8y146	190	23	(	(	-LRB-
cord-024061-gxv8y146	190	24	102	102	CD
cord-024061-gxv8y146	190	25	)	)	-RRB-
cord-024061-gxv8y146	190	26	.	.	.
cord-024061-gxv8y146	191	1	Similar	similar	JJ
cord-024061-gxv8y146	191	2	,	,	,
cord-024061-gxv8y146	191	3	but	but	CC
cord-024061-gxv8y146	191	4	more	more	RBR
cord-024061-gxv8y146	191	5	complex	complex	JJ
cord-024061-gxv8y146	191	6	,	,	,
cord-024061-gxv8y146	191	7	implementations	implementation	NNS
cord-024061-gxv8y146	191	8	of	of	IN
cord-024061-gxv8y146	191	9	mathematical	mathematical	JJ
cord-024061-gxv8y146	191	10	epidemiology	epidemiology	NN
cord-024061-gxv8y146	191	11	in	in	IN
cord-024061-gxv8y146	191	12	the	the	DT
cord-024061-gxv8y146	191	13	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	191	14	models	model	NNS
cord-024061-gxv8y146	191	15	were	be	VBD
cord-024061-gxv8y146	191	16	described	describe	VBN
cord-024061-gxv8y146	191	17	elsewhere	elsewhere	RB
cord-024061-gxv8y146	191	18	(	(	-LRB-
cord-024061-gxv8y146	191	19	103	103	CD
cord-024061-gxv8y146	191	20	,	,	,
cord-024061-gxv8y146	191	21	104	104	CD
cord-024061-gxv8y146	191	22	)	)	-RRB-
cord-024061-gxv8y146	191	23	.	.	.
cord-024061-gxv8y146	192	1	Prior	prior	JJ
cord-024061-gxv8y146	192	2	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	192	3	models	model	NNS
cord-024061-gxv8y146	192	4	described	describe	VBN
cord-024061-gxv8y146	192	5	above	above	RB
cord-024061-gxv8y146	192	6	can	can	MD
cord-024061-gxv8y146	192	7	be	be	VB
cord-024061-gxv8y146	192	8	readily	readily	RB
cord-024061-gxv8y146	192	9	selected	select	VBN
cord-024061-gxv8y146	192	10	and	and	CC
cord-024061-gxv8y146	192	11	set	set	VBN
cord-024061-gxv8y146	192	12	using	use	VBG
cord-024061-gxv8y146	192	13	a	a	DT
cord-024061-gxv8y146	192	14	graphical	graphical	JJ
cord-024061-gxv8y146	192	15	user	user	NN
cord-024061-gxv8y146	192	16	interface	interface	NN
cord-024061-gxv8y146	192	17	(	(	-LRB-
cord-024061-gxv8y146	192	18	GUI	GUI	NNP
cord-024061-gxv8y146	192	19	)	)	-RRB-
cord-024061-gxv8y146	192	20	implemented	implement	VBD
cord-024061-gxv8y146	192	21	within	within	IN
cord-024061-gxv8y146	192	22	the	the	DT
cord-024061-gxv8y146	192	23	BEAST	BEAST	NNP
cord-024061-gxv8y146	192	24	software	software	NN
cord-024061-gxv8y146	192	25	package	package	NN
cord-024061-gxv8y146	192	26	,	,	,
cord-024061-gxv8y146	192	27	namely	namely	RB
cord-024061-gxv8y146	192	28	,	,	,
cord-024061-gxv8y146	192	29	the	the	DT
cord-024061-gxv8y146	192	30	Bayesian	Bayesian	NNP
cord-024061-gxv8y146	192	31	Evolutionary	Evolutionary	NNP
cord-024061-gxv8y146	192	32	Analysis	Analysis	NNP
cord-024061-gxv8y146	192	33	Utility	Utility	NNP
cord-024061-gxv8y146	192	34	(	(	-LRB-
cord-024061-gxv8y146	192	35	BEAUti	BEAUti	NNP
cord-024061-gxv8y146	192	36	)	)	-RRB-
cord-024061-gxv8y146	192	37	(	(	-LRB-
cord-024061-gxv8y146	192	38	24	24	CD
cord-024061-gxv8y146	192	39	,	,	,
cord-024061-gxv8y146	192	40	105	105	CD
cord-024061-gxv8y146	192	41	)	)	-RRB-
cord-024061-gxv8y146	192	42	.	.	.
cord-024061-gxv8y146	193	1	After	after	IN
cord-024061-gxv8y146	193	2	selecting	select	VBG
cord-024061-gxv8y146	193	3	and	and	CC
cord-024061-gxv8y146	193	4	setting	set	VBG
cord-024061-gxv8y146	193	5	the	the	DT
cord-024061-gxv8y146	193	6	models	model	NNS
cord-024061-gxv8y146	193	7	,	,	,
cord-024061-gxv8y146	193	8	the	the	DT
cord-024061-gxv8y146	193	9	software	software	NN
cord-024061-gxv8y146	193	10	generates	generate	VBZ
cord-024061-gxv8y146	193	11	a	a	DT
cord-024061-gxv8y146	193	12	standard	standard	JJ
cord-024061-gxv8y146	193	13	XML	xml	NN
cord-024061-gxv8y146	193	14	format	format	NN
cord-024061-gxv8y146	193	15	structured	structure	VBN
cord-024061-gxv8y146	193	16	text	text	NN
cord-024061-gxv8y146	193	17	file	file	NN
cord-024061-gxv8y146	193	18	allowing	allow	VBG
cord-024061-gxv8y146	193	19	for	for	IN
cord-024061-gxv8y146	193	20	flexible	flexible	JJ
cord-024061-gxv8y146	193	21	modifications	modification	NNS
cord-024061-gxv8y146	193	22	for	for	IN
cord-024061-gxv8y146	193	23	more	more	RBR
cord-024061-gxv8y146	193	24	sophisticated	sophisticated	JJ
cord-024061-gxv8y146	193	25	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	193	26	models	model	NNS
cord-024061-gxv8y146	193	27	.	.	.
cord-024061-gxv8y146	194	1	However	however	RB
cord-024061-gxv8y146	194	2	,	,	,
cord-024061-gxv8y146	194	3	the	the	DT
cord-024061-gxv8y146	194	4	generated	generate	VBN
cord-024061-gxv8y146	194	5	XML	xml	NN
cord-024061-gxv8y146	194	6	files	file	NNS
cord-024061-gxv8y146	194	7	are	be	VBP
cord-024061-gxv8y146	194	8	very	very	RB
cord-024061-gxv8y146	194	9	complex	complex	JJ
cord-024061-gxv8y146	194	10	in	in	IN
cord-024061-gxv8y146	194	11	their	-PRON-	PRP$
cord-024061-gxv8y146	194	12	structure	structure	NN
cord-024061-gxv8y146	194	13	,	,	,
cord-024061-gxv8y146	194	14	and	and	CC
cord-024061-gxv8y146	194	15	therefore	therefore	RB
cord-024061-gxv8y146	194	16	,	,	,
cord-024061-gxv8y146	194	17	manual	manual	JJ
cord-024061-gxv8y146	194	18	modifications	modification	NNS
cord-024061-gxv8y146	194	19	should	should	MD
cord-024061-gxv8y146	194	20	be	be	VB
cord-024061-gxv8y146	194	21	made	make	VBN
cord-024061-gxv8y146	194	22	by	by	IN
cord-024061-gxv8y146	194	23	relevant	relevant	JJ
cord-024061-gxv8y146	194	24	experts	expert	NNS
cord-024061-gxv8y146	194	25	to	to	TO
cord-024061-gxv8y146	194	26	avoid	avoid	VB
cord-024061-gxv8y146	194	27	the	the	DT
cord-024061-gxv8y146	194	28	introduction	introduction	NN
cord-024061-gxv8y146	194	29	of	of	IN
cord-024061-gxv8y146	194	30	significant	significant	JJ
cord-024061-gxv8y146	194	31	error	error	NN
cord-024061-gxv8y146	194	32	into	into	IN
cord-024061-gxv8y146	194	33	the	the	DT
cord-024061-gxv8y146	194	34	model	model	NN
cord-024061-gxv8y146	194	35	(	(	-LRB-
cord-024061-gxv8y146	194	36	105	105	CD
cord-024061-gxv8y146	194	37	)	)	-RRB-
cord-024061-gxv8y146	194	38	.	.	.
cord-024061-gxv8y146	195	1	Additional	additional	JJ
cord-024061-gxv8y146	195	2	tutorials	tutorial	NNS
cord-024061-gxv8y146	195	3	on	on	IN
cord-024061-gxv8y146	195	4	selecting	select	VBG
cord-024061-gxv8y146	195	5	and	and	CC
cord-024061-gxv8y146	195	6	setting	set	VBG
cord-024061-gxv8y146	195	7	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	195	8	models	model	NNS
cord-024061-gxv8y146	195	9	using	use	VBG
cord-024061-gxv8y146	195	10	BEAST	BEAST	NNP
cord-024061-gxv8y146	195	11	1.X	1.x	CD
cord-024061-gxv8y146	195	12	are	be	VBP
cord-024061-gxv8y146	195	13	available	available	JJ
cord-024061-gxv8y146	195	14	elsewhere	elsewhere	RB
cord-024061-gxv8y146	195	15	(	(	-LRB-
cord-024061-gxv8y146	195	16	106	106	CD
cord-024061-gxv8y146	195	17	)	)	-RRB-
cord-024061-gxv8y146	195	18	(	(	-LRB-
cord-024061-gxv8y146	195	19	107	107	CD
cord-024061-gxv8y146	195	20	)	)	-RRB-
cord-024061-gxv8y146	196	1	(	(	-LRB-
cord-024061-gxv8y146	196	2	108	108	CD
cord-024061-gxv8y146	196	3	)	)	-RRB-
cord-024061-gxv8y146	196	4	.	.	.
cord-024061-gxv8y146	197	1	Phylodynamic	Phylodynamic	NNP
cord-024061-gxv8y146	197	2	model	model	NN
cord-024061-gxv8y146	197	3	selection	selection	NN
cord-024061-gxv8y146	197	4	is	be	VBZ
cord-024061-gxv8y146	197	5	a	a	DT
cord-024061-gxv8y146	197	6	critical	critical	JJ
cord-024061-gxv8y146	197	7	component	component	NN
cord-024061-gxv8y146	197	8	of	of	IN
cord-024061-gxv8y146	197	9	the	the	DT
cord-024061-gxv8y146	197	10	analysis	analysis	NN
cord-024061-gxv8y146	197	11	pipeline	pipeline	NN
cord-024061-gxv8y146	197	12	described	describe	VBN
cord-024061-gxv8y146	197	13	in	in	IN
cord-024061-gxv8y146	197	14	Figure	Figure	NNP
cord-024061-gxv8y146	197	15	1	1	CD
cord-024061-gxv8y146	197	16	,	,	,
cord-024061-gxv8y146	197	17	simply	simply	RB
cord-024061-gxv8y146	197	18	because	because	IN
cord-024061-gxv8y146	197	19	different	different	JJ
cord-024061-gxv8y146	197	20	pathogens	pathogen	NNS
cord-024061-gxv8y146	197	21	or	or	CC
cord-024061-gxv8y146	197	22	gene	gene	NN
cord-024061-gxv8y146	197	23	segments	segment	NNS
cord-024061-gxv8y146	197	24	have	have	VBP
cord-024061-gxv8y146	197	25	different	different	JJ
cord-024061-gxv8y146	197	26	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	197	27	processes	process	NNS
cord-024061-gxv8y146	197	28	.	.	.
cord-024061-gxv8y146	198	1	Therefore	therefore	RB
cord-024061-gxv8y146	198	2	,	,	,
cord-024061-gxv8y146	198	3	using	use	VBG
cord-024061-gxv8y146	198	4	a	a	DT
cord-024061-gxv8y146	198	5	single	single	JJ
cord-024061-gxv8y146	198	6	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	198	7	model	model	NN
cord-024061-gxv8y146	198	8	with	with	IN
cord-024061-gxv8y146	198	9	similar	similar	JJ
cord-024061-gxv8y146	198	10	priors	prior	NNS
cord-024061-gxv8y146	198	11	to	to	TO
cord-024061-gxv8y146	198	12	infer	infer	VB
cord-024061-gxv8y146	198	13	the	the	DT
cord-024061-gxv8y146	198	14	evolution	evolution	NN
cord-024061-gxv8y146	198	15	of	of	IN
cord-024061-gxv8y146	198	16	multiple	multiple	JJ
cord-024061-gxv8y146	198	17	pathogens	pathogen	NNS
cord-024061-gxv8y146	198	18	may	may	MD
cord-024061-gxv8y146	198	19	be	be	VB
cord-024061-gxv8y146	198	20	biologically	biologically	RB
cord-024061-gxv8y146	198	21	implausible	implausible	JJ
cord-024061-gxv8y146	198	22	,	,	,
cord-024061-gxv8y146	198	23	leading	lead	VBG
cord-024061-gxv8y146	198	24	to	to	IN
cord-024061-gxv8y146	198	25	biased	biased	JJ
cord-024061-gxv8y146	198	26	inferences	inference	NNS
cord-024061-gxv8y146	198	27	.	.	.
cord-024061-gxv8y146	199	1	Exploring	explore	VBG
cord-024061-gxv8y146	199	2	the	the	DT
cord-024061-gxv8y146	199	3	fit	fit	NN
cord-024061-gxv8y146	199	4	of	of	IN
cord-024061-gxv8y146	199	5	the	the	DT
cord-024061-gxv8y146	199	6	sequence	sequence	NN
cord-024061-gxv8y146	199	7	data	datum	NNS
cord-024061-gxv8y146	199	8	to	to	IN
cord-024061-gxv8y146	199	9	different	different	JJ
cord-024061-gxv8y146	199	10	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	199	11	model	model	NN
cord-024061-gxv8y146	199	12	combinations	combination	NNS
cord-024061-gxv8y146	199	13	,	,	,
cord-024061-gxv8y146	199	14	in	in	IN
cord-024061-gxv8y146	199	15	terms	term	NNS
cord-024061-gxv8y146	199	16	of	of	IN
cord-024061-gxv8y146	199	17	substitution	substitution	NN
cord-024061-gxv8y146	199	18	,	,	,
cord-024061-gxv8y146	199	19	branch	branch	NN
cord-024061-gxv8y146	199	20	rate	rate	NN
cord-024061-gxv8y146	199	21	,	,	,
cord-024061-gxv8y146	199	22	and	and	CC
cord-024061-gxv8y146	199	23	node	node	NN
cord-024061-gxv8y146	199	24	age	age	NN
cord-024061-gxv8y146	199	25	to	to	TO
cord-024061-gxv8y146	199	26	infer	infer	VB
cord-024061-gxv8y146	199	27	divergence	divergence	NN
cord-024061-gxv8y146	199	28	times	time	NNS
cord-024061-gxv8y146	199	29	,	,	,
cord-024061-gxv8y146	199	30	Time	time	NN
cord-024061-gxv8y146	199	31	to	to	IN
cord-024061-gxv8y146	199	32	the	the	DT
cord-024061-gxv8y146	199	33	Most	most	RBS
cord-024061-gxv8y146	199	34	Recent	Recent	NNP
cord-024061-gxv8y146	199	35	Common	Common	NNP
cord-024061-gxv8y146	199	36	Ancestor	Ancestor	NNP
cord-024061-gxv8y146	199	37	(	(	-LRB-
cord-024061-gxv8y146	199	38	TMRCAs	TMRCAs	NNP
cord-024061-gxv8y146	199	39	)	)	-RRB-
cord-024061-gxv8y146	199	40	,	,	,
cord-024061-gxv8y146	199	41	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	199	42	rates	rate	NNS
cord-024061-gxv8y146	199	43	is	be	VBZ
cord-024061-gxv8y146	199	44	the	the	DT
cord-024061-gxv8y146	199	45	best	good	JJS
cord-024061-gxv8y146	199	46	strategy	strategy	NN
cord-024061-gxv8y146	199	47	for	for	IN
cord-024061-gxv8y146	199	48	ensuring	ensure	VBG
cord-024061-gxv8y146	199	49	accurate	accurate	JJ
cord-024061-gxv8y146	199	50	estimation	estimation	NN
cord-024061-gxv8y146	199	51	of	of	IN
cord-024061-gxv8y146	199	52	posterior	posterior	JJ
cord-024061-gxv8y146	199	53	inferences	inference	NNS
cord-024061-gxv8y146	199	54	.	.	.
cord-024061-gxv8y146	200	1	For	for	IN
cord-024061-gxv8y146	200	2	inferring	infer	VBG
cord-024061-gxv8y146	200	3	viral	viral	JJ
cord-024061-gxv8y146	200	4	demographic	demographic	JJ
cord-024061-gxv8y146	200	5	history	history	NN
cord-024061-gxv8y146	200	6	,	,	,
cord-024061-gxv8y146	200	7	our	-PRON-	PRP$
cord-024061-gxv8y146	200	8	suggested	suggested	JJ
cord-024061-gxv8y146	200	9	pipeline	pipeline	NN
cord-024061-gxv8y146	200	10	(	(	-LRB-
cord-024061-gxv8y146	200	11	Figure	figure	NN
cord-024061-gxv8y146	200	12	1	1	CD
cord-024061-gxv8y146	200	13	)	)	-RRB-
cord-024061-gxv8y146	200	14	leads	lead	VBZ
cord-024061-gxv8y146	200	15	to	to	IN
cord-024061-gxv8y146	200	16	the	the	DT
cord-024061-gxv8y146	200	17	generation	generation	NN
cord-024061-gxv8y146	200	18	of	of	IN
cord-024061-gxv8y146	200	19	eight	eight	CD
cord-024061-gxv8y146	200	20	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	200	21	model	model	NN
cord-024061-gxv8y146	200	22	combinations	combination	NNS
cord-024061-gxv8y146	200	23	for	for	IN
cord-024061-gxv8y146	200	24	a	a	DT
cord-024061-gxv8y146	200	25	single	single	JJ
cord-024061-gxv8y146	200	26	gene	gene	NN
cord-024061-gxv8y146	200	27	segment	segment	NN
cord-024061-gxv8y146	200	28	,	,	,
cord-024061-gxv8y146	200	29	including	include	VBG
cord-024061-gxv8y146	200	30	the	the	DT
cord-024061-gxv8y146	200	31	selected	select	VBN
cord-024061-gxv8y146	200	32	substitution	substitution	NN
cord-024061-gxv8y146	200	33	model	model	NN
cord-024061-gxv8y146	200	34	(	(	-LRB-
cord-024061-gxv8y146	200	35	by	by	IN
cord-024061-gxv8y146	200	36	PartitionFinder	PartitionFinder	NNP
cord-024061-gxv8y146	200	37	)	)	-RRB-
cord-024061-gxv8y146	200	38	,	,	,
cord-024061-gxv8y146	200	39	two	two	CD
cord-024061-gxv8y146	200	40	branch	branch	NN
cord-024061-gxv8y146	200	41	rate	rate	NN
cord-024061-gxv8y146	200	42	priors	prior	NNS
cord-024061-gxv8y146	200	43	(	(	-LRB-
cord-024061-gxv8y146	200	44	UCED	UCED	NNP
cord-024061-gxv8y146	200	45	and	and	CC
cord-024061-gxv8y146	200	46	UCLN	UCLN	NNP
cord-024061-gxv8y146	200	47	)	)	-RRB-
cord-024061-gxv8y146	200	48	,	,	,
cord-024061-gxv8y146	200	49	and	and	CC
cord-024061-gxv8y146	200	50	four	four	CD
cord-024061-gxv8y146	200	51	node	node	NN
cord-024061-gxv8y146	200	52	-	-	HYPH
cord-024061-gxv8y146	200	53	age	age	NN
cord-024061-gxv8y146	200	54	priors	prior	NNS
cord-024061-gxv8y146	200	55	(	(	-LRB-
cord-024061-gxv8y146	200	56	Cp	Cp	NNP
cord-024061-gxv8y146	200	57	,	,	,
cord-024061-gxv8y146	200	58	Ex	Ex	NNP
cord-024061-gxv8y146	200	59	,	,	,
cord-024061-gxv8y146	200	60	Exg	Exg	NNP
cord-024061-gxv8y146	200	61	,	,	,
cord-024061-gxv8y146	200	62	and	and	CC
cord-024061-gxv8y146	200	63	SG	SG	NNP
cord-024061-gxv8y146	200	64	)	)	-RRB-
cord-024061-gxv8y146	200	65	.	.	.
cord-024061-gxv8y146	201	1	However	however	RB
cord-024061-gxv8y146	201	2	,	,	,
cord-024061-gxv8y146	201	3	when	when	WRB
cord-024061-gxv8y146	201	4	inferring	infer	VBG
cord-024061-gxv8y146	201	5	phylogeographic	phylogeographic	JJ
cord-024061-gxv8y146	201	6	history	history	NN
cord-024061-gxv8y146	201	7	using	use	VBG
cord-024061-gxv8y146	201	8	DTA	DTA	NNP
cord-024061-gxv8y146	201	9	,	,	,
cord-024061-gxv8y146	201	10	we	-PRON-	PRP
cord-024061-gxv8y146	201	11	suggest	suggest	VBP
cord-024061-gxv8y146	201	12	exploring	explore	VBG
cord-024061-gxv8y146	201	13	both	both	CC
cord-024061-gxv8y146	201	14	Sym	Sym	NNP
cord-024061-gxv8y146	201	15	and	and	CC
cord-024061-gxv8y146	201	16	Asym	Asym	NNP
cord-024061-gxv8y146	201	17	BSSVS	BSSVS	NNP
cord-024061-gxv8y146	201	18	models	model	NNS
cord-024061-gxv8y146	201	19	(	(	-LRB-
cord-024061-gxv8y146	201	20	Figure	figure	NN
cord-024061-gxv8y146	201	21	1	1	CD
cord-024061-gxv8y146	201	22	)	)	-RRB-
cord-024061-gxv8y146	201	23	,	,	,
cord-024061-gxv8y146	201	24	which	which	WDT
cord-024061-gxv8y146	201	25	will	will	MD
cord-024061-gxv8y146	201	26	lead	lead	VB
cord-024061-gxv8y146	201	27	to	to	IN
cord-024061-gxv8y146	201	28	the	the	DT
cord-024061-gxv8y146	201	29	generation	generation	NN
cord-024061-gxv8y146	201	30	of	of	IN
cord-024061-gxv8y146	201	31	16	16	CD
cord-024061-gxv8y146	201	32	models	model	NNS
cord-024061-gxv8y146	201	33	.	.	.
cord-024061-gxv8y146	202	1	Our	-PRON-	PRP$
cord-024061-gxv8y146	202	2	rigorous	rigorous	JJ
cord-024061-gxv8y146	202	3	analytical	analytical	JJ
cord-024061-gxv8y146	202	4	pipeline	pipeline	NN
cord-024061-gxv8y146	202	5	is	be	VBZ
cord-024061-gxv8y146	202	6	indeed	indeed	RB
cord-024061-gxv8y146	202	7	timely	timely	JJ
cord-024061-gxv8y146	202	8	and	and	CC
cord-024061-gxv8y146	202	9	computationally	computationally	RB
cord-024061-gxv8y146	202	10	demanding	demanding	JJ
cord-024061-gxv8y146	202	11	,	,	,
cord-024061-gxv8y146	202	12	but	but	CC
cord-024061-gxv8y146	202	13	on	on	IN
cord-024061-gxv8y146	202	14	the	the	DT
cord-024061-gxv8y146	202	15	other	other	JJ
cord-024061-gxv8y146	202	16	hand	hand	NN
cord-024061-gxv8y146	202	17	,	,	,
cord-024061-gxv8y146	202	18	it	-PRON-	PRP
cord-024061-gxv8y146	202	19	will	will	MD
cord-024061-gxv8y146	202	20	lead	lead	VB
cord-024061-gxv8y146	202	21	to	to	IN
cord-024061-gxv8y146	202	22	the	the	DT
cord-024061-gxv8y146	202	23	selection	selection	NN
cord-024061-gxv8y146	202	24	of	of	IN
cord-024061-gxv8y146	202	25	the	the	DT
cord-024061-gxv8y146	202	26	most	most	RBS
cord-024061-gxv8y146	202	27	realistic	realistic	JJ
cord-024061-gxv8y146	202	28	model	model	NN
cord-024061-gxv8y146	202	29	that	that	WDT
cord-024061-gxv8y146	202	30	fits	fit	VBZ
cord-024061-gxv8y146	202	31	the	the	DT
cord-024061-gxv8y146	202	32	sequence	sequence	NN
cord-024061-gxv8y146	202	33	data	datum	NNS
cord-024061-gxv8y146	202	34	with	with	IN
cord-024061-gxv8y146	202	35	confidence	confidence	NN
cord-024061-gxv8y146	202	36	.	.	.
cord-024061-gxv8y146	203	1	However	however	RB
cord-024061-gxv8y146	203	2	,	,	,
cord-024061-gxv8y146	203	3	this	this	DT
cord-024061-gxv8y146	203	4	suggested	suggest	VBD
cord-024061-gxv8y146	203	5	pipeline	pipeline	NN
cord-024061-gxv8y146	203	6	is	be	VBZ
cord-024061-gxv8y146	203	7	not	not	RB
cord-024061-gxv8y146	203	8	a	a	DT
cord-024061-gxv8y146	203	9	strict	strict	JJ
cord-024061-gxv8y146	203	10	set	set	NN
cord-024061-gxv8y146	203	11	of	of	IN
cord-024061-gxv8y146	203	12	procedures	procedure	NNS
cord-024061-gxv8y146	203	13	that	that	WDT
cord-024061-gxv8y146	203	14	will	will	MD
cord-024061-gxv8y146	203	15	ensure	ensure	VB
cord-024061-gxv8y146	203	16	appropriate	appropriate	JJ
cord-024061-gxv8y146	203	17	inferences	inference	NNS
cord-024061-gxv8y146	203	18	,	,	,
cord-024061-gxv8y146	203	19	and	and	CC
cord-024061-gxv8y146	203	20	therefore	therefore	RB
cord-024061-gxv8y146	203	21	,	,	,
cord-024061-gxv8y146	203	22	researchers	researcher	NNS
cord-024061-gxv8y146	203	23	may	may	MD
cord-024061-gxv8y146	203	24	explore	explore	VB
cord-024061-gxv8y146	203	25	other	other	JJ
cord-024061-gxv8y146	203	26	model	model	NN
cord-024061-gxv8y146	203	27	or	or	CC
cord-024061-gxv8y146	203	28	analytical	analytical	JJ
cord-024061-gxv8y146	203	29	pipelines	pipeline	NNS
cord-024061-gxv8y146	203	30	relevant	relevant	JJ
cord-024061-gxv8y146	203	31	to	to	IN
cord-024061-gxv8y146	203	32	their	-PRON-	PRP$
cord-024061-gxv8y146	203	33	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	203	34	hypotheses	hypothesis	NNS
cord-024061-gxv8y146	203	35	.	.	.
cord-024061-gxv8y146	204	1	It	-PRON-	PRP
cord-024061-gxv8y146	204	2	is	be	VBZ
cord-024061-gxv8y146	204	3	worth	worth	JJ
cord-024061-gxv8y146	204	4	noting	note	VBG
cord-024061-gxv8y146	204	5	that	that	IN
cord-024061-gxv8y146	204	6	the	the	DT
cord-024061-gxv8y146	204	7	computational	computational	JJ
cord-024061-gxv8y146	204	8	efficiency	efficiency	NN
cord-024061-gxv8y146	204	9	has	have	VBZ
cord-024061-gxv8y146	204	10	been	be	VBN
cord-024061-gxv8y146	204	11	substantially	substantially	RB
cord-024061-gxv8y146	204	12	improved	improve	VBN
cord-024061-gxv8y146	204	13	in	in	IN
cord-024061-gxv8y146	204	14	BEAST	BEAST	NNP
cord-024061-gxv8y146	204	15	version	version	NN
cord-024061-gxv8y146	204	16	1.10	1.10	CD
cord-024061-gxv8y146	204	17	and	and	CC
cord-024061-gxv8y146	204	18	the	the	DT
cord-024061-gxv8y146	204	19	accompanied	accompany	VBN
cord-024061-gxv8y146	204	20	software	software	NN
cord-024061-gxv8y146	204	21	library	library	NN
cord-024061-gxv8y146	204	22	Broadplatform	Broadplatform	NNP
cord-024061-gxv8y146	204	23	Evolutionary	Evolutionary	NNP
cord-024061-gxv8y146	204	24	Analysis	Analysis	NNP
cord-024061-gxv8y146	204	25	General	General	NNP
cord-024061-gxv8y146	204	26	Likelihood	Likelihood	NNP
cord-024061-gxv8y146	204	27	Evaluator	Evaluator	NNP
cord-024061-gxv8y146	204	28	(	(	-LRB-
cord-024061-gxv8y146	204	29	BEAGLE	BEAGLE	NNP
cord-024061-gxv8y146	204	30	;	;	:
cord-024061-gxv8y146	204	31	permits	permit	VBZ
cord-024061-gxv8y146	204	32	flexible	flexible	JJ
cord-024061-gxv8y146	204	33	parallel	parallel	JJ
cord-024061-gxv8y146	204	34	computing	computing	NN
cord-024061-gxv8y146	204	35	)	)	-RRB-
cord-024061-gxv8y146	204	36	when	when	WRB
cord-024061-gxv8y146	204	37	compared	compare	VBN
cord-024061-gxv8y146	204	38	to	to	IN
cord-024061-gxv8y146	204	39	earlier	early	JJR
cord-024061-gxv8y146	204	40	versions	version	NNS
cord-024061-gxv8y146	204	41	.	.	.
cord-024061-gxv8y146	205	1	The	the	DT
cord-024061-gxv8y146	205	2	fit	fit	NN
cord-024061-gxv8y146	205	3	of	of	IN
cord-024061-gxv8y146	205	4	the	the	DT
cord-024061-gxv8y146	205	5	sequence	sequence	NN
cord-024061-gxv8y146	205	6	data	datum	NNS
cord-024061-gxv8y146	205	7	to	to	IN
cord-024061-gxv8y146	205	8	the	the	DT
cord-024061-gxv8y146	205	9	most	most	RBS
cord-024061-gxv8y146	205	10	realistic	realistic	JJ
cord-024061-gxv8y146	205	11	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	205	12	model	model	NN
cord-024061-gxv8y146	205	13	can	can	MD
cord-024061-gxv8y146	205	14	be	be	VB
cord-024061-gxv8y146	205	15	assessed	assess	VBN
cord-024061-gxv8y146	205	16	through	through	IN
cord-024061-gxv8y146	205	17	simultaneous	simultaneous	JJ
cord-024061-gxv8y146	205	18	estimating	estimate	VBG
cord-024061-gxv8y146	205	19	the	the	DT
cord-024061-gxv8y146	205	20	marginal	marginal	JJ
cord-024061-gxv8y146	205	21	likelihood	likelihood	NN
cord-024061-gxv8y146	205	22	(	(	-LRB-
cord-024061-gxv8y146	205	23	MLL	MLL	NNP
cord-024061-gxv8y146	205	24	)	)	-RRB-
cord-024061-gxv8y146	205	25	using	use	VBG
cord-024061-gxv8y146	205	26	the	the	DT
cord-024061-gxv8y146	205	27	path	path	NN
cord-024061-gxv8y146	205	28	sampling	sampling	NN
cord-024061-gxv8y146	205	29	(	(	-LRB-
cord-024061-gxv8y146	205	30	PS	PS	NNP
cord-024061-gxv8y146	205	31	)	)	-RRB-
cord-024061-gxv8y146	205	32	(	(	-LRB-
cord-024061-gxv8y146	205	33	25	25	CD
cord-024061-gxv8y146	205	34	)	)	-RRB-
cord-024061-gxv8y146	205	35	and	and	CC
cord-024061-gxv8y146	205	36	stepping	step	VBG
cord-024061-gxv8y146	205	37	-	-	HYPH
cord-024061-gxv8y146	205	38	stone	stone	NN
cord-024061-gxv8y146	205	39	sampling	sampling	NN
cord-024061-gxv8y146	205	40	(	(	-LRB-
cord-024061-gxv8y146	205	41	SS	SS	NNP
cord-024061-gxv8y146	205	42	)	)	-RRB-
cord-024061-gxv8y146	205	43	(	(	-LRB-
cord-024061-gxv8y146	205	44	109	109	CD
cord-024061-gxv8y146	205	45	)	)	-RRB-
cord-024061-gxv8y146	205	46	implemented	implement	VBN
cord-024061-gxv8y146	205	47	in	in	IN
cord-024061-gxv8y146	205	48	BEAUti	BEAUti	NNP
cord-024061-gxv8y146	205	49	using	use	VBG
cord-024061-gxv8y146	205	50	the	the	DT
cord-024061-gxv8y146	205	51	standard	standard	JJ
cord-024061-gxv8y146	205	52	settings	setting	NNS
cord-024061-gxv8y146	205	53	(	(	-LRB-
cord-024061-gxv8y146	205	54	i.e.	i.e.	FW
cord-024061-gxv8y146	205	55	,	,	,
cord-024061-gxv8y146	205	56	simulating	simulate	VBG
cord-024061-gxv8y146	205	57	across	across	IN
cord-024061-gxv8y146	205	58	100	100	CD
cord-024061-gxv8y146	205	59	samples	sample	NNS
cord-024061-gxv8y146	205	60	for	for	IN
cord-024061-gxv8y146	205	61	1	1	CD
cord-024061-gxv8y146	205	62	million	million	CD
cord-024061-gxv8y146	205	63	cycle	cycle	NN
cord-024061-gxv8y146	205	64	from	from	IN
cord-024061-gxv8y146	205	65	the	the	DT
cord-024061-gxv8y146	205	66	posterior	posterior	NN
cord-024061-gxv8y146	205	67	to	to	IN
cord-024061-gxv8y146	205	68	the	the	DT
cord-024061-gxv8y146	205	69	prior	prior	JJ
cord-024061-gxv8y146	205	70	with	with	IN
cord-024061-gxv8y146	205	71	a	a	DT
cord-024061-gxv8y146	205	72	prior	prior	JJ
cord-024061-gxv8y146	205	73	reflection	reflection	NN
cord-024061-gxv8y146	205	74	point	point	NN
cord-024061-gxv8y146	205	75	of	of	IN
cord-024061-gxv8y146	205	76	Beta	Beta	NNP
cord-024061-gxv8y146	205	77	[	[	-LRB-
cord-024061-gxv8y146	205	78	0.3	0.3	CD
cord-024061-gxv8y146	205	79	,	,	,
cord-024061-gxv8y146	205	80	1.0	1.0	CD
cord-024061-gxv8y146	205	81	]	]	-RRB-
cord-024061-gxv8y146	205	82	)	)	-RRB-
cord-024061-gxv8y146	205	83	.	.	.
cord-024061-gxv8y146	206	1	The	the	DT
cord-024061-gxv8y146	206	2	joint	joint	JJ
cord-024061-gxv8y146	206	3	posterior	posterior	JJ
cord-024061-gxv8y146	206	4	probability	probability	NN
cord-024061-gxv8y146	206	5	density	density	NN
cord-024061-gxv8y146	206	6	of	of	IN
cord-024061-gxv8y146	206	7	the	the	DT
cord-024061-gxv8y146	206	8	models	model	NNS
cord-024061-gxv8y146	206	9	'	'	POS
cord-024061-gxv8y146	206	10	parameters	parameter	NNS
cord-024061-gxv8y146	206	11	is	be	VBZ
cord-024061-gxv8y146	206	12	estimated	estimate	VBN
cord-024061-gxv8y146	206	13	by	by	IN
cord-024061-gxv8y146	206	14	the	the	DT
cord-024061-gxv8y146	206	15	MCMC	MCMC	NNP
cord-024061-gxv8y146	206	16	algorithms	algorithm	NNS
cord-024061-gxv8y146	206	17	.	.	.
cord-024061-gxv8y146	207	1	Setting	set	VBG
cord-024061-gxv8y146	207	2	the	the	DT
cord-024061-gxv8y146	207	3	appropriate	appropriate	JJ
cord-024061-gxv8y146	207	4	length	length	NN
cord-024061-gxv8y146	207	5	of	of	IN
cord-024061-gxv8y146	207	6	the	the	DT
cord-024061-gxv8y146	207	7	MCMC	MCMC	NNP
cord-024061-gxv8y146	207	8	chains	chain	NNS
cord-024061-gxv8y146	207	9	(	(	-LRB-
cord-024061-gxv8y146	207	10	i.e.	i.e.	FW
cord-024061-gxv8y146	207	11	,	,	,
cord-024061-gxv8y146	207	12	number	number	NN
cord-024061-gxv8y146	207	13	of	of	IN
cord-024061-gxv8y146	207	14	cycles	cycle	NNS
cord-024061-gxv8y146	207	15	)	)	-RRB-
cord-024061-gxv8y146	207	16	to	to	TO
cord-024061-gxv8y146	207	17	ensure	ensure	VB
cord-024061-gxv8y146	207	18	model	model	NN
cord-024061-gxv8y146	207	19	convergence	convergence	NN
cord-024061-gxv8y146	207	20	is	be	VBZ
cord-024061-gxv8y146	207	21	dependent	dependent	JJ
cord-024061-gxv8y146	207	22	on	on	IN
cord-024061-gxv8y146	207	23	the	the	DT
cord-024061-gxv8y146	207	24	number	number	NN
cord-024061-gxv8y146	207	25	of	of	IN
cord-024061-gxv8y146	207	26	sequences	sequence	NNS
cord-024061-gxv8y146	207	27	in	in	IN
cord-024061-gxv8y146	207	28	the	the	DT
cord-024061-gxv8y146	207	29	dataset	dataset	NN
cord-024061-gxv8y146	207	30	.	.	.
cord-024061-gxv8y146	208	1	One	one	CD
cord-024061-gxv8y146	208	2	recommended	recommend	VBN
cord-024061-gxv8y146	208	3	approach	approach	NN
cord-024061-gxv8y146	208	4	is	be	VBZ
cord-024061-gxv8y146	208	5	to	to	TO
cord-024061-gxv8y146	208	6	quadratically	quadratically	RB
cord-024061-gxv8y146	208	7	increase	increase	VB
cord-024061-gxv8y146	208	8	the	the	DT
cord-024061-gxv8y146	208	9	chain	chain	NN
cord-024061-gxv8y146	208	10	length	length	NN
cord-024061-gxv8y146	208	11	relative	relative	JJ
cord-024061-gxv8y146	208	12	to	to	IN
cord-024061-gxv8y146	208	13	the	the	DT
cord-024061-gxv8y146	208	14	number	number	NN
cord-024061-gxv8y146	208	15	of	of	IN
cord-024061-gxv8y146	208	16	sequences	sequence	NNS
cord-024061-gxv8y146	208	17	(	(	-LRB-
cord-024061-gxv8y146	208	18	e.g.	e.g.	RB
cord-024061-gxv8y146	208	19	,	,	,
cord-024061-gxv8y146	208	20	4	4	CD
cord-024061-gxv8y146	208	21	million	million	CD
cord-024061-gxv8y146	208	22	states	state	NNS
cord-024061-gxv8y146	208	23	per	per	IN
cord-024061-gxv8y146	208	24	sequence	sequence	NN
cord-024061-gxv8y146	208	25	)	)	-RRB-
cord-024061-gxv8y146	208	26	(	(	-LRB-
cord-024061-gxv8y146	208	27	110	110	CD
cord-024061-gxv8y146	208	28	)	)	-RRB-
cord-024061-gxv8y146	208	29	.	.	.
cord-024061-gxv8y146	209	1	Finally	finally	RB
cord-024061-gxv8y146	209	2	,	,	,
cord-024061-gxv8y146	209	3	creating	create	VBG
cord-024061-gxv8y146	209	4	duplicate	duplicate	JJ
cord-024061-gxv8y146	209	5	runs	run	NNS
cord-024061-gxv8y146	209	6	from	from	IN
cord-024061-gxv8y146	209	7	each	each	DT
cord-024061-gxv8y146	209	8	generated	generate	VBN
cord-024061-gxv8y146	209	9	model	model	NN
cord-024061-gxv8y146	209	10	can	can	MD
cord-024061-gxv8y146	209	11	aid	aid	VB
cord-024061-gxv8y146	209	12	in	in	IN
cord-024061-gxv8y146	209	13	assessing	assess	VBG
cord-024061-gxv8y146	209	14	the	the	DT
cord-024061-gxv8y146	209	15	performance	performance	NN
cord-024061-gxv8y146	209	16	stability	stability	NN
cord-024061-gxv8y146	209	17	of	of	IN
cord-024061-gxv8y146	209	18	the	the	DT
cord-024061-gxv8y146	209	19	MCMC	MCMC	NNP
cord-024061-gxv8y146	209	20	simulations	simulation	NNS
cord-024061-gxv8y146	209	21	and	and	CC
cord-024061-gxv8y146	209	22	their	-PRON-	PRP$
cord-024061-gxv8y146	209	23	MLL	MLL	NNP
cord-024061-gxv8y146	209	24	estimates	estimate	NNS
cord-024061-gxv8y146	209	25	.	.	.
cord-024061-gxv8y146	210	1	MCMC	MCMC	NNP
cord-024061-gxv8y146	210	2	log	log	NN
cord-024061-gxv8y146	210	3	-	-	HYPH
cord-024061-gxv8y146	210	4	files	file	NNS
cord-024061-gxv8y146	210	5	generated	generate	VBN
cord-024061-gxv8y146	210	6	by	by	IN
cord-024061-gxv8y146	210	7	BEAST	BEAST	NNP
cord-024061-gxv8y146	210	8	can	can	MD
cord-024061-gxv8y146	210	9	be	be	VB
cord-024061-gxv8y146	210	10	thoroughly	thoroughly	RB
cord-024061-gxv8y146	210	11	evaluated	evaluate	VBN
cord-024061-gxv8y146	210	12	using	use	VBG
cord-024061-gxv8y146	210	13	a	a	DT
cord-024061-gxv8y146	210	14	friendly	friendly	JJ
cord-024061-gxv8y146	210	15	GUI	GUI	NNP
cord-024061-gxv8y146	210	16	software	software	NN
cord-024061-gxv8y146	210	17	known	know	VBN
cord-024061-gxv8y146	210	18	as	as	IN
cord-024061-gxv8y146	210	19	Tracer	Tracer	NNP
cord-024061-gxv8y146	210	20	(	(	-LRB-
cord-024061-gxv8y146	210	21	111	111	CD
cord-024061-gxv8y146	210	22	)	)	-RRB-
cord-024061-gxv8y146	210	23	.	.	.
cord-024061-gxv8y146	211	1	The	the	DT
cord-024061-gxv8y146	211	2	software	software	NN
cord-024061-gxv8y146	211	3	provides	provide	VBZ
cord-024061-gxv8y146	211	4	a	a	DT
cord-024061-gxv8y146	211	5	simultaneous	simultaneous	JJ
cord-024061-gxv8y146	211	6	platform	platform	NN
cord-024061-gxv8y146	211	7	for	for	IN
cord-024061-gxv8y146	211	8	summarizing	summarize	VBG
cord-024061-gxv8y146	211	9	and	and	CC
cord-024061-gxv8y146	211	10	visualizing	visualize	VBG
cord-024061-gxv8y146	211	11	posterior	posterior	JJ
cord-024061-gxv8y146	211	12	estimates	estimate	NNS
cord-024061-gxv8y146	211	13	.	.	.
cord-024061-gxv8y146	212	1	Appropriate	appropriate	JJ
cord-024061-gxv8y146	212	2	model	model	NN
cord-024061-gxv8y146	212	3	convergence	convergence	NN
cord-024061-gxv8y146	212	4	can	can	MD
cord-024061-gxv8y146	212	5	be	be	VB
cord-024061-gxv8y146	212	6	evaluated	evaluate	VBN
cord-024061-gxv8y146	212	7	by	by	IN
cord-024061-gxv8y146	212	8	examining	examine	VBG
cord-024061-gxv8y146	212	9	the	the	DT
cord-024061-gxv8y146	212	10	MCMC	MCMC	NNP
cord-024061-gxv8y146	212	11	mixing	mix	VBG
cord-024061-gxv8y146	212	12	(	(	-LRB-
cord-024061-gxv8y146	212	13	based	base	VBN
cord-024061-gxv8y146	212	14	on	on	IN
cord-024061-gxv8y146	212	15	acceptance	acceptance	NN
cord-024061-gxv8y146	212	16	ratios	ratio	NNS
cord-024061-gxv8y146	212	17	)	)	-RRB-
cord-024061-gxv8y146	212	18	using	use	VBG
cord-024061-gxv8y146	212	19	trace	trace	NN
cord-024061-gxv8y146	212	20	plots	plot	NNS
cord-024061-gxv8y146	212	21	,	,	,
cord-024061-gxv8y146	212	22	after	after	IN
cord-024061-gxv8y146	212	23	discarding	discard	VBG
cord-024061-gxv8y146	212	24	the	the	DT
cord-024061-gxv8y146	212	25	10	10	CD
cord-024061-gxv8y146	212	26	%	%	NN
cord-024061-gxv8y146	212	27	of	of	IN
cord-024061-gxv8y146	212	28	the	the	DT
cord-024061-gxv8y146	212	29	sample	sample	NN
cord-024061-gxv8y146	212	30	(	(	-LRB-
cord-024061-gxv8y146	212	31	the	the	DT
cord-024061-gxv8y146	212	32	"	"	``
cord-024061-gxv8y146	212	33	burn	burn	NN
cord-024061-gxv8y146	212	34	-	-	HYPH
cord-024061-gxv8y146	212	35	in	in	NN
cord-024061-gxv8y146	212	36	"	"	''
cord-024061-gxv8y146	212	37	)	)	-RRB-
cord-024061-gxv8y146	212	38	.	.	.
cord-024061-gxv8y146	213	1	Besides	besides	RB
cord-024061-gxv8y146	213	2	,	,	,
cord-024061-gxv8y146	213	3	assessing	assess	VBG
cord-024061-gxv8y146	213	4	the	the	DT
cord-024061-gxv8y146	213	5	estimates	estimate	NNS
cord-024061-gxv8y146	213	6	of	of	IN
cord-024061-gxv8y146	213	7	the	the	DT
cord-024061-gxv8y146	213	8	effective	effective	JJ
cord-024061-gxv8y146	213	9	sample	sample	NN
cord-024061-gxv8y146	213	10	sizes	size	NNS
cord-024061-gxv8y146	213	11	(	(	-LRB-
cord-024061-gxv8y146	213	12	ESS	ESS	NNP
cord-024061-gxv8y146	213	13	)	)	-RRB-
cord-024061-gxv8y146	213	14	for	for	IN
cord-024061-gxv8y146	213	15	each	each	DT
cord-024061-gxv8y146	213	16	parameter	parameter	NN
cord-024061-gxv8y146	213	17	,	,	,
cord-024061-gxv8y146	213	18	in	in	IN
cord-024061-gxv8y146	213	19	which	which	WDT
cord-024061-gxv8y146	213	20	ESS	ESS	NNP
cord-024061-gxv8y146	213	21	values	value	NNS
cord-024061-gxv8y146	213	22	>	>	XX
cord-024061-gxv8y146	213	23	200	200	CD
cord-024061-gxv8y146	213	24	,	,	,
cord-024061-gxv8y146	213	25	indicates	indicate	VBZ
cord-024061-gxv8y146	213	26	good	good	JJ
cord-024061-gxv8y146	213	27	model	model	NN
cord-024061-gxv8y146	213	28	convergence	convergence	NN
cord-024061-gxv8y146	213	29	(	(	-LRB-
cord-024061-gxv8y146	213	30	111	111	CD
cord-024061-gxv8y146	213	31	)	)	-RRB-
cord-024061-gxv8y146	213	32	.	.	.
cord-024061-gxv8y146	214	1	On	on	IN
cord-024061-gxv8y146	214	2	some	some	DT
cord-024061-gxv8y146	214	3	occasions	occasion	NNS
cord-024061-gxv8y146	214	4	,	,	,
cord-024061-gxv8y146	214	5	good	good	JJ
cord-024061-gxv8y146	214	6	model	model	NN
cord-024061-gxv8y146	214	7	convergence	convergence	NN
cord-024061-gxv8y146	214	8	does	do	VBZ
cord-024061-gxv8y146	214	9	not	not	RB
cord-024061-gxv8y146	214	10	ensure	ensure	VB
cord-024061-gxv8y146	214	11	consistent	consistent	JJ
cord-024061-gxv8y146	214	12	parameter	parameter	NN
cord-024061-gxv8y146	214	13	estimation	estimation	NN
cord-024061-gxv8y146	214	14	due	due	IN
cord-024061-gxv8y146	214	15	to	to	IN
cord-024061-gxv8y146	214	16	the	the	DT
cord-024061-gxv8y146	214	17	use	use	NN
cord-024061-gxv8y146	214	18	of	of	IN
cord-024061-gxv8y146	214	19	non	non	JJ
cord-024061-gxv8y146	214	20	-	-	JJ
cord-024061-gxv8y146	214	21	informative	informative	JJ
cord-024061-gxv8y146	214	22	priors	prior	NNS
cord-024061-gxv8y146	214	23	implemented	implement	VBN
cord-024061-gxv8y146	214	24	in	in	IN
cord-024061-gxv8y146	214	25	BEAUti	BEAUti	NNP
cord-024061-gxv8y146	214	26	.	.	.
cord-024061-gxv8y146	215	1	Therefore	therefore	RB
cord-024061-gxv8y146	215	2	,	,	,
cord-024061-gxv8y146	215	3	it	-PRON-	PRP
cord-024061-gxv8y146	215	4	is	be	VBZ
cord-024061-gxv8y146	215	5	critical	critical	JJ
cord-024061-gxv8y146	215	6	to	to	TO
cord-024061-gxv8y146	215	7	compare	compare	VB
cord-024061-gxv8y146	215	8	posterior	posterior	JJ
cord-024061-gxv8y146	215	9	parameter	parameter	NN
cord-024061-gxv8y146	215	10	estimates	estimate	NNS
cord-024061-gxv8y146	215	11	(	(	-LRB-
cord-024061-gxv8y146	215	12	e.g.	e.g.	RB
cord-024061-gxv8y146	215	13	,	,	,
cord-024061-gxv8y146	215	14	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	215	15	rates	rate	NNS
cord-024061-gxv8y146	215	16	,	,	,
cord-024061-gxv8y146	215	17	population	population	NN
cord-024061-gxv8y146	215	18	growth	growth	NN
cord-024061-gxv8y146	215	19	rates	rate	NNS
cord-024061-gxv8y146	215	20	,	,	,
cord-024061-gxv8y146	215	21	PS	PS	NNP
cord-024061-gxv8y146	215	22	,	,	,
cord-024061-gxv8y146	215	23	and	and	CC
cord-024061-gxv8y146	215	24	SS	SS	NNP
cord-024061-gxv8y146	215	25	MLL	MLL	NNP
cord-024061-gxv8y146	215	26	estimates	estimate	VBZ
cord-024061-gxv8y146	215	27	)	)	-RRB-
cord-024061-gxv8y146	215	28	between	between	IN
cord-024061-gxv8y146	215	29	independent	independent	JJ
cord-024061-gxv8y146	215	30	runs	run	NNS
cord-024061-gxv8y146	215	31	for	for	IN
cord-024061-gxv8y146	215	32	each	each	DT
cord-024061-gxv8y146	215	33	model	model	NN
cord-024061-gxv8y146	215	34	to	to	TO
cord-024061-gxv8y146	215	35	warrant	warrant	VB
cord-024061-gxv8y146	215	36	that	that	IN
cord-024061-gxv8y146	215	37	each	each	DT
cord-024061-gxv8y146	215	38	parameter	parameter	NN
cord-024061-gxv8y146	215	39	is	be	VBZ
cord-024061-gxv8y146	215	40	closely	closely	RB
cord-024061-gxv8y146	215	41	identical	identical	JJ
cord-024061-gxv8y146	215	42	to	to	IN
cord-024061-gxv8y146	215	43	its	-PRON-	PRP$
cord-024061-gxv8y146	215	44	duplicate	duplicate	JJ
cord-024061-gxv8y146	215	45	run	run	NN
cord-024061-gxv8y146	215	46	.	.	.
cord-024061-gxv8y146	216	1	In	in	IN
cord-024061-gxv8y146	216	2	case	case	NN
cord-024061-gxv8y146	216	3	of	of	IN
cord-024061-gxv8y146	216	4	improper	improper	JJ
cord-024061-gxv8y146	216	5	model	model	NN
cord-024061-gxv8y146	216	6	convergence	convergence	NN
cord-024061-gxv8y146	216	7	and	and	CC
cord-024061-gxv8y146	216	8	inconsistent	inconsistent	JJ
cord-024061-gxv8y146	216	9	parameter	parameter	NN
cord-024061-gxv8y146	216	10	estimation	estimation	NN
cord-024061-gxv8y146	216	11	,	,	,
cord-024061-gxv8y146	216	12	it	-PRON-	PRP
cord-024061-gxv8y146	216	13	is	be	VBZ
cord-024061-gxv8y146	216	14	recommended	recommend	VBN
cord-024061-gxv8y146	216	15	to	to	IN
cord-024061-gxv8y146	216	16	either	either	CC
cord-024061-gxv8y146	216	17	increase	increase	VB
cord-024061-gxv8y146	216	18	the	the	DT
cord-024061-gxv8y146	216	19	length	length	NN
cord-024061-gxv8y146	216	20	of	of	IN
cord-024061-gxv8y146	216	21	the	the	DT
cord-024061-gxv8y146	216	22	MCMC	MCMC	NNP
cord-024061-gxv8y146	216	23	chain	chain	NN
cord-024061-gxv8y146	216	24	or	or	CC
cord-024061-gxv8y146	216	25	the	the	DT
cord-024061-gxv8y146	216	26	use	use	NN
cord-024061-gxv8y146	216	27	of	of	IN
cord-024061-gxv8y146	216	28	informative	informative	JJ
cord-024061-gxv8y146	216	29	priors	prior	NNS
cord-024061-gxv8y146	216	30	from	from	IN
cord-024061-gxv8y146	216	31	previous	previous	JJ
cord-024061-gxv8y146	216	32	MCMC	MCMC	NNP
cord-024061-gxv8y146	216	33	runs	run	VBZ
cord-024061-gxv8y146	216	34	for	for	IN
cord-024061-gxv8y146	216	35	the	the	DT
cord-024061-gxv8y146	216	36	same	same	JJ
cord-024061-gxv8y146	216	37	gene	gene	NN
cord-024061-gxv8y146	216	38	segment	segment	NN
cord-024061-gxv8y146	216	39	or	or	CC
cord-024061-gxv8y146	216	40	pathogen	pathogen	NN
cord-024061-gxv8y146	216	41	.	.	.
cord-024061-gxv8y146	217	1	Model	model	NN
cord-024061-gxv8y146	217	2	selection	selection	NN
cord-024061-gxv8y146	217	3	is	be	VBZ
cord-024061-gxv8y146	217	4	achieved	achieve	VBN
cord-024061-gxv8y146	217	5	by	by	IN
cord-024061-gxv8y146	217	6	comparing	compare	VBG
cord-024061-gxv8y146	217	7	the	the	DT
cord-024061-gxv8y146	217	8	Bayes	Bayes	NNP
cord-024061-gxv8y146	217	9	factor	factor	NN
cord-024061-gxv8y146	217	10	(	(	-LRB-
cord-024061-gxv8y146	217	11	BF	BF	NNP
cord-024061-gxv8y146	217	12	)	)	-RRB-
cord-024061-gxv8y146	217	13	of	of	IN
cord-024061-gxv8y146	217	14	the	the	DT
cord-024061-gxv8y146	217	15	resulting	result	VBG
cord-024061-gxv8y146	217	16	MLL	MLL	NNP
cord-024061-gxv8y146	217	17	estimates	estimate	NNS
cord-024061-gxv8y146	217	18	(	(	-LRB-
cord-024061-gxv8y146	217	19	from	from	IN
cord-024061-gxv8y146	217	20	the	the	DT
cord-024061-gxv8y146	217	21	PS	PS	NNP
cord-024061-gxv8y146	217	22	and	and	CC
cord-024061-gxv8y146	217	23	SS	SS	NNP
cord-024061-gxv8y146	217	24	methods	method	NNS
cord-024061-gxv8y146	217	25	)	)	-RRB-
cord-024061-gxv8y146	217	26	of	of	IN
cord-024061-gxv8y146	217	27	their	-PRON-	PRP$
cord-024061-gxv8y146	217	28	corresponding	correspond	VBG
cord-024061-gxv8y146	217	29	candidate	candidate	NN
cord-024061-gxv8y146	217	30	models	model	NNS
cord-024061-gxv8y146	217	31	(	(	-LRB-
cord-024061-gxv8y146	217	32	25	25	CD
cord-024061-gxv8y146	217	33	)	)	-RRB-
cord-024061-gxv8y146	217	34	.	.	.
cord-024061-gxv8y146	218	1	Briefly	briefly	RB
cord-024061-gxv8y146	218	2	,	,	,
cord-024061-gxv8y146	218	3	the	the	DT
cord-024061-gxv8y146	218	4	BF	BF	NNP
cord-024061-gxv8y146	218	5	value	value	NN
cord-024061-gxv8y146	218	6	of	of	IN
cord-024061-gxv8y146	218	7	the	the	DT
cord-024061-gxv8y146	218	8	candidate	candidate	NN
cord-024061-gxv8y146	218	9	models	model	NNS
cord-024061-gxv8y146	218	10	is	be	VBZ
cord-024061-gxv8y146	218	11	summarized	summarize	VBN
cord-024061-gxv8y146	218	12	using	use	VBG
cord-024061-gxv8y146	218	13	a	a	DT
cord-024061-gxv8y146	218	14	matrix	matrix	NN
cord-024061-gxv8y146	218	15	and	and	CC
cord-024061-gxv8y146	218	16	computed	compute	VBN
cord-024061-gxv8y146	218	17	using	use	VBG
cord-024061-gxv8y146	218	18	the	the	DT
cord-024061-gxv8y146	218	19	following	follow	VBG
cord-024061-gxv8y146	218	20	equation	equation	NN
cord-024061-gxv8y146	218	21	:	:	:
cord-024061-gxv8y146	218	22	where	where	WRB
cord-024061-gxv8y146	218	23	Y	Y	NNP
cord-024061-gxv8y146	218	24	is	be	VBZ
cord-024061-gxv8y146	218	25	the	the	DT
cord-024061-gxv8y146	218	26	sequence	sequence	NN
cord-024061-gxv8y146	218	27	data	data	NN
cord-024061-gxv8y146	218	28	,	,	,
cord-024061-gxv8y146	218	29	M	M	NNP
cord-024061-gxv8y146	219	1	i	i	PRP
cord-024061-gxv8y146	219	2	is	be	VBZ
cord-024061-gxv8y146	219	3	the	the	DT
cord-024061-gxv8y146	219	4	candidate	candidate	NN
cord-024061-gxv8y146	219	5	model	model	NN
cord-024061-gxv8y146	219	6	"	"	``
cord-024061-gxv8y146	219	7	i	i	NNP
cord-024061-gxv8y146	219	8	,	,	,
cord-024061-gxv8y146	219	9	"	"	''
cord-024061-gxv8y146	219	10	M	M	NNP
cord-024061-gxv8y146	219	11	j	j	NNP
cord-024061-gxv8y146	219	12	is	be	VBZ
cord-024061-gxv8y146	219	13	the	the	DT
cord-024061-gxv8y146	219	14	competing	compete	VBG
cord-024061-gxv8y146	219	15	candidate	candidate	NN
cord-024061-gxv8y146	219	16	model	model	NN
cord-024061-gxv8y146	219	17	"	"	``
cord-024061-gxv8y146	219	18	j	j	NNP
cord-024061-gxv8y146	219	19	,	,	,
cord-024061-gxv8y146	219	20	"	"	''
cord-024061-gxv8y146	219	21	and	and	CC
cord-024061-gxv8y146	219	22	lnp	lnp	NNP
cord-024061-gxv8y146	219	23	(	(	-LRB-
cord-024061-gxv8y146	219	24	Y|M	Y|M	NNP
cord-024061-gxv8y146	219	25	)	)	-RRB-
cord-024061-gxv8y146	219	26	is	be	VBZ
cord-024061-gxv8y146	219	27	the	the	DT
cord-024061-gxv8y146	219	28	MLL	MLL	NNP
cord-024061-gxv8y146	219	29	estimate	estimate	NN
cord-024061-gxv8y146	219	30	by	by	IN
cord-024061-gxv8y146	219	31	either	either	DT
cord-024061-gxv8y146	219	32	SS	SS	NNP
cord-024061-gxv8y146	219	33	or	or	CC
cord-024061-gxv8y146	219	34	PS	PS	NNP
cord-024061-gxv8y146	219	35	simulators	simulator	NNS
cord-024061-gxv8y146	219	36	.	.	.
cord-024061-gxv8y146	220	1	BF	BF	NNP
cord-024061-gxv8y146	220	2	values	value	NNS
cord-024061-gxv8y146	220	3	estimated	estimate	VBN
cord-024061-gxv8y146	220	4	by	by	IN
cord-024061-gxv8y146	220	5	the	the	DT
cord-024061-gxv8y146	220	6	SS	SS	NNP
cord-024061-gxv8y146	220	7	method	method	NN
cord-024061-gxv8y146	220	8	are	be	VBP
cord-024061-gxv8y146	220	9	summarized	summarize	VBN
cord-024061-gxv8y146	220	10	on	on	IN
cord-024061-gxv8y146	220	11	the	the	DT
cord-024061-gxv8y146	220	12	upper	upper	JJ
cord-024061-gxv8y146	220	13	off	off	JJ
cord-024061-gxv8y146	220	14	-	-	HYPH
cord-024061-gxv8y146	220	15	diagonal	diagonal	NN
cord-024061-gxv8y146	220	16	of	of	IN
cord-024061-gxv8y146	220	17	the	the	DT
cord-024061-gxv8y146	220	18	matrix	matrix	NN
cord-024061-gxv8y146	220	19	,	,	,
cord-024061-gxv8y146	220	20	while	while	IN
cord-024061-gxv8y146	220	21	BF	BF	NNP
cord-024061-gxv8y146	220	22	values	value	NNS
cord-024061-gxv8y146	220	23	estimated	estimate	VBN
cord-024061-gxv8y146	220	24	by	by	IN
cord-024061-gxv8y146	220	25	the	the	DT
cord-024061-gxv8y146	220	26	PS	PS	NNP
cord-024061-gxv8y146	220	27	method	method	NN
cord-024061-gxv8y146	220	28	are	be	VBP
cord-024061-gxv8y146	220	29	summarized	summarize	VBN
cord-024061-gxv8y146	220	30	on	on	IN
cord-024061-gxv8y146	220	31	the	the	DT
cord-024061-gxv8y146	220	32	lower	low	JJR
cord-024061-gxv8y146	220	33	off	off	JJ
cord-024061-gxv8y146	220	34	-	-	HYPH
cord-024061-gxv8y146	220	35	diagonal	diagonal	NN
cord-024061-gxv8y146	220	36	of	of	IN
cord-024061-gxv8y146	220	37	the	the	DT
cord-024061-gxv8y146	220	38	matrix	matrix	NN
cord-024061-gxv8y146	220	39	.	.	.
cord-024061-gxv8y146	221	1	A	a	DT
cord-024061-gxv8y146	221	2	model	model	NN
cord-024061-gxv8y146	221	3	with	with	IN
cord-024061-gxv8y146	221	4	horizontal	horizontal	JJ
cord-024061-gxv8y146	221	5	(	(	-LRB-
cord-024061-gxv8y146	221	6	i.e.	i.e.	FW
cord-024061-gxv8y146	221	7	,	,	,
cord-024061-gxv8y146	221	8	row	row	VB
cord-024061-gxv8y146	221	9	side	side	NN
cord-024061-gxv8y146	221	10	of	of	IN
cord-024061-gxv8y146	221	11	the	the	DT
cord-024061-gxv8y146	221	12	maxtrix	maxtrix	NNP
cord-024061-gxv8y146	221	13	)	)	-RRB-
cord-024061-gxv8y146	221	14	BF	BF	NNP
cord-024061-gxv8y146	221	15	values	value	VBZ
cord-024061-gxv8y146	221	16	greater	great	JJR
cord-024061-gxv8y146	221	17	than	than	IN
cord-024061-gxv8y146	221	18	other	other	JJ
cord-024061-gxv8y146	221	19	candidate	candidate	NN
cord-024061-gxv8y146	221	20	models	model	NNS
cord-024061-gxv8y146	221	21	is	be	VBZ
cord-024061-gxv8y146	221	22	selected	select	VBN
cord-024061-gxv8y146	221	23	.	.	.
cord-024061-gxv8y146	222	1	Additional	additional	JJ
cord-024061-gxv8y146	222	2	applied	apply	VBN
cord-024061-gxv8y146	222	3	examples	example	NNS
cord-024061-gxv8y146	222	4	on	on	IN
cord-024061-gxv8y146	222	5	model	model	NN
cord-024061-gxv8y146	222	6	selection	selection	NN
cord-024061-gxv8y146	222	7	using	use	VBG
cord-024061-gxv8y146	222	8	BEAST	BEAST	NNP
cord-024061-gxv8y146	222	9	1.X	1.x	CD
cord-024061-gxv8y146	222	10	are	be	VBP
cord-024061-gxv8y146	222	11	available	available	JJ
cord-024061-gxv8y146	222	12	elsewhere	elsewhere	RB
cord-024061-gxv8y146	222	13	(	(	-LRB-
cord-024061-gxv8y146	222	14	106	106	CD
cord-024061-gxv8y146	222	15	)	)	-RRB-
cord-024061-gxv8y146	222	16	(	(	-LRB-
cord-024061-gxv8y146	222	17	107	107	CD
cord-024061-gxv8y146	222	18	)	)	-RRB-
cord-024061-gxv8y146	223	1	(	(	-LRB-
cord-024061-gxv8y146	223	2	108	108	CD
cord-024061-gxv8y146	223	3	)	)	-RRB-
cord-024061-gxv8y146	223	4	.	.	.
cord-024061-gxv8y146	224	1	The	the	DT
cord-024061-gxv8y146	224	2	ultimate	ultimate	JJ
cord-024061-gxv8y146	224	3	goal	goal	NN
cord-024061-gxv8y146	224	4	of	of	IN
cord-024061-gxv8y146	224	5	the	the	DT
cord-024061-gxv8y146	224	6	model	model	NN
cord-024061-gxv8y146	224	7	selection	selection	NN
cord-024061-gxv8y146	224	8	procedure	procedure	NN
cord-024061-gxv8y146	224	9	is	be	VBZ
cord-024061-gxv8y146	224	10	to	to	TO
cord-024061-gxv8y146	224	11	find	find	VB
cord-024061-gxv8y146	224	12	the	the	DT
cord-024061-gxv8y146	224	13	best	good	JJS
cord-024061-gxv8y146	224	14	fitting	fitting	JJ
cord-024061-gxv8y146	224	15	model	model	NN
cord-024061-gxv8y146	224	16	that	that	WDT
cord-024061-gxv8y146	224	17	generated	generate	VBD
cord-024061-gxv8y146	224	18	the	the	DT
cord-024061-gxv8y146	224	19	data	datum	NNS
cord-024061-gxv8y146	224	20	,	,	,
cord-024061-gxv8y146	224	21	while	while	IN
cord-024061-gxv8y146	224	22	combining	combine	VBG
cord-024061-gxv8y146	224	23	simplicity	simplicity	NN
cord-024061-gxv8y146	224	24	with	with	IN
cord-024061-gxv8y146	224	25	biological	biological	JJ
cord-024061-gxv8y146	224	26	realism	realism	NN
cord-024061-gxv8y146	224	27	,	,	,
cord-024061-gxv8y146	224	28	to	to	TO
cord-024061-gxv8y146	224	29	appropriately	appropriately	RB
cord-024061-gxv8y146	224	30	represent	represent	VB
cord-024061-gxv8y146	224	31	the	the	DT
cord-024061-gxv8y146	224	32	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	224	33	characteristics	characteristic	NNS
cord-024061-gxv8y146	224	34	of	of	IN
cord-024061-gxv8y146	224	35	the	the	DT
cord-024061-gxv8y146	224	36	pathogen	pathogen	NN
cord-024061-gxv8y146	224	37	under	under	IN
cord-024061-gxv8y146	224	38	study	study	NN
cord-024061-gxv8y146	224	39	(	(	-LRB-
cord-024061-gxv8y146	224	40	25	25	CD
cord-024061-gxv8y146	224	41	,	,	,
cord-024061-gxv8y146	224	42	112	112	CD
cord-024061-gxv8y146	224	43	)	)	-RRB-
cord-024061-gxv8y146	224	44	.	.	.
cord-024061-gxv8y146	225	1	Inferred	infer	VBN
cord-024061-gxv8y146	225	2	relative	relative	JJ
cord-024061-gxv8y146	225	3	genetic	genetic	JJ
cord-024061-gxv8y146	225	4	diversity	diversity	NN
cord-024061-gxv8y146	225	5	through	through	IN
cord-024061-gxv8y146	225	6	time	time	NN
cord-024061-gxv8y146	225	7	(	(	-LRB-
cord-024061-gxv8y146	225	8	or	or	CC
cord-024061-gxv8y146	225	9	other	other	JJ
cord-024061-gxv8y146	225	10	reconstructed	reconstruct	VBN
cord-024061-gxv8y146	225	11	demographic	demographic	JJ
cord-024061-gxv8y146	225	12	trajectories	trajectory	NNS
cord-024061-gxv8y146	225	13	)	)	-RRB-
cord-024061-gxv8y146	225	14	and	and	CC
cord-024061-gxv8y146	225	15	its	-PRON-	PRP$
cord-024061-gxv8y146	225	16	highest	high	JJS
cord-024061-gxv8y146	225	17	posterior	posterior	JJ
cord-024061-gxv8y146	225	18	density	density	NN
cord-024061-gxv8y146	225	19	(	(	-LRB-
cord-024061-gxv8y146	225	20	HPD	HPD	NNP
cord-024061-gxv8y146	225	21	)	)	-RRB-
cord-024061-gxv8y146	225	22	interval	interval	NN
cord-024061-gxv8y146	225	23	can	can	MD
cord-024061-gxv8y146	225	24	be	be	VB
cord-024061-gxv8y146	225	25	summarized	summarize	VBN
cord-024061-gxv8y146	225	26	using	use	VBG
cord-024061-gxv8y146	225	27	sky	sky	NN
cord-024061-gxv8y146	225	28	plots	plot	NNS
cord-024061-gxv8y146	225	29	(	(	-LRB-
cord-024061-gxv8y146	225	30	e.g.	e.g.	RB
cord-024061-gxv8y146	225	31	,	,	,
cord-024061-gxv8y146	225	32	Skygrid	Skygrid	NNP
cord-024061-gxv8y146	225	33	plot	plot	NN
cord-024061-gxv8y146	225	34	)	)	-RRB-
cord-024061-gxv8y146	225	35	generated	generate	VBN
cord-024061-gxv8y146	225	36	by	by	IN
cord-024061-gxv8y146	225	37	Tracer	Tracer	NNP
cord-024061-gxv8y146	225	38	.	.	.
cord-024061-gxv8y146	226	1	Similarly	similarly	RB
cord-024061-gxv8y146	226	2	,	,	,
cord-024061-gxv8y146	226	3	estimates	estimate	NNS
cord-024061-gxv8y146	226	4	of	of	IN
cord-024061-gxv8y146	226	5	divergence	divergence	NN
cord-024061-gxv8y146	226	6	time	time	NN
cord-024061-gxv8y146	226	7	,	,	,
cord-024061-gxv8y146	226	8	TMRCAs	tmrca	NNS
cord-024061-gxv8y146	226	9	,	,	,
cord-024061-gxv8y146	226	10	and	and	CC
cord-024061-gxv8y146	226	11	substitution	substitution	NN
cord-024061-gxv8y146	226	12	rate	rate	NN
cord-024061-gxv8y146	226	13	/	/	SYM
cord-024061-gxv8y146	226	14	site	site	NN
cord-024061-gxv8y146	226	15	/	/	SYM
cord-024061-gxv8y146	226	16	year	year	NN
cord-024061-gxv8y146	226	17	with	with	IN
cord-024061-gxv8y146	226	18	their	-PRON-	PRP$
cord-024061-gxv8y146	226	19	HPD	HPD	NNP
cord-024061-gxv8y146	226	20	intervals	interval	NNS
cord-024061-gxv8y146	226	21	can	can	MD
cord-024061-gxv8y146	226	22	be	be	VB
cord-024061-gxv8y146	226	23	summarized	summarize	VBN
cord-024061-gxv8y146	226	24	in	in	IN
cord-024061-gxv8y146	226	25	Tracer	Tracer	NNP
cord-024061-gxv8y146	226	26	using	use	VBG
cord-024061-gxv8y146	226	27	either	either	CC
cord-024061-gxv8y146	226	28	box	box	NN
cord-024061-gxv8y146	226	29	or	or	CC
cord-024061-gxv8y146	226	30	violin	violin	NN
cord-024061-gxv8y146	226	31	plots	plot	NNS
cord-024061-gxv8y146	226	32	(	(	-LRB-
cord-024061-gxv8y146	226	33	111	111	CD
cord-024061-gxv8y146	226	34	)	)	-RRB-
cord-024061-gxv8y146	226	35	.	.	.
cord-024061-gxv8y146	227	1	Also	also	RB
cord-024061-gxv8y146	227	2	,	,	,
cord-024061-gxv8y146	227	3	Tracer	Tracer	NNP
cord-024061-gxv8y146	227	4	provides	provide	VBZ
cord-024061-gxv8y146	227	5	a	a	DT
cord-024061-gxv8y146	227	6	flexible	flexible	JJ
cord-024061-gxv8y146	227	7	platform	platform	NN
cord-024061-gxv8y146	227	8	for	for	IN
cord-024061-gxv8y146	227	9	simultaneous	simultaneous	JJ
cord-024061-gxv8y146	227	10	comparison	comparison	NN
cord-024061-gxv8y146	227	11	of	of	IN
cord-024061-gxv8y146	227	12	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	227	13	estimates	estimate	NNS
cord-024061-gxv8y146	227	14	inferred	infer	VBN
cord-024061-gxv8y146	227	15	by	by	IN
cord-024061-gxv8y146	227	16	multiple	multiple	JJ
cord-024061-gxv8y146	227	17	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	227	18	models	model	NNS
cord-024061-gxv8y146	227	19	.	.	.
cord-024061-gxv8y146	228	1	Next	next	RB
cord-024061-gxv8y146	228	2	,	,	,
cord-024061-gxv8y146	228	3	the	the	DT
cord-024061-gxv8y146	228	4	resulting	result	VBG
cord-024061-gxv8y146	228	5	marginal	marginal	JJ
cord-024061-gxv8y146	228	6	posterior	posterior	JJ
cord-024061-gxv8y146	228	7	probability	probability	NN
cord-024061-gxv8y146	228	8	density	density	NN
cord-024061-gxv8y146	228	9	of	of	IN
cord-024061-gxv8y146	228	10	the	the	DT
cord-024061-gxv8y146	228	11	selected	select	VBN
cord-024061-gxv8y146	228	12	model	model	NN
cord-024061-gxv8y146	228	13	is	be	VBZ
cord-024061-gxv8y146	228	14	summarized	summarize	VBN
cord-024061-gxv8y146	228	15	as	as	IN
cord-024061-gxv8y146	228	16	a	a	DT
cord-024061-gxv8y146	228	17	maximum	maximum	JJ
cord-024061-gxv8y146	228	18	clade	clade	NN
cord-024061-gxv8y146	228	19	credible	credible	JJ
cord-024061-gxv8y146	228	20	(	(	-LRB-
cord-024061-gxv8y146	228	21	MCC	MCC	NNP
cord-024061-gxv8y146	228	22	)	)	-RRB-
cord-024061-gxv8y146	228	23	tree	tree	NN
cord-024061-gxv8y146	228	24	using	use	VBG
cord-024061-gxv8y146	228	25	TreeAnotator	TreeAnotator	NNP
cord-024061-gxv8y146	228	26	(	(	-LRB-
cord-024061-gxv8y146	228	27	24	24	CD
cord-024061-gxv8y146	228	28	)	)	-RRB-
cord-024061-gxv8y146	228	29	to	to	TO
cord-024061-gxv8y146	228	30	generate	generate	VB
cord-024061-gxv8y146	228	31	a	a	DT
cord-024061-gxv8y146	228	32	tree	tree	NN
cord-024061-gxv8y146	228	33	file	file	NN
cord-024061-gxv8y146	228	34	.	.	.
cord-024061-gxv8y146	229	1	MCC	MCC	NNP
cord-024061-gxv8y146	229	2	tree	tree	NN
cord-024061-gxv8y146	229	3	(	(	-LRB-
cord-024061-gxv8y146	229	4	from	from	IN
cord-024061-gxv8y146	229	5	the	the	DT
cord-024061-gxv8y146	229	6	tree	tree	NN
cord-024061-gxv8y146	229	7	file	file	NN
cord-024061-gxv8y146	229	8	)	)	-RRB-
cord-024061-gxv8y146	229	9	can	can	MD
cord-024061-gxv8y146	229	10	be	be	VB
cord-024061-gxv8y146	229	11	then	then	RB
cord-024061-gxv8y146	229	12	visualized	visualize	VBN
cord-024061-gxv8y146	229	13	and	and	CC
cord-024061-gxv8y146	229	14	annotated	annotate	VBN
cord-024061-gxv8y146	229	15	with	with	IN
cord-024061-gxv8y146	229	16	either	either	DT
cord-024061-gxv8y146	229	17	posterior	posterior	JJ
cord-024061-gxv8y146	229	18	support	support	NN
cord-024061-gxv8y146	229	19	values	value	NNS
cord-024061-gxv8y146	229	20	or	or	CC
cord-024061-gxv8y146	229	21	RSSPs	rssp	NNS
cord-024061-gxv8y146	229	22	of	of	IN
cord-024061-gxv8y146	229	23	the	the	DT
cord-024061-gxv8y146	229	24	discrete	discrete	JJ
cord-024061-gxv8y146	229	25	traits	trait	NNS
cord-024061-gxv8y146	229	26	at	at	IN
cord-024061-gxv8y146	229	27	the	the	DT
cord-024061-gxv8y146	229	28	internal	internal	JJ
cord-024061-gxv8y146	229	29	nodes	node	NNS
cord-024061-gxv8y146	229	30	using	use	VBG
cord-024061-gxv8y146	229	31	FigTree	FigTree	NNP
cord-024061-gxv8y146	229	32	(	(	-LRB-
cord-024061-gxv8y146	229	33	113	113	CD
cord-024061-gxv8y146	229	34	)	)	-RRB-
cord-024061-gxv8y146	229	35	.	.	.
cord-024061-gxv8y146	230	1	In	in	IN
cord-024061-gxv8y146	230	2	addition	addition	NN
cord-024061-gxv8y146	230	3	,	,	,
cord-024061-gxv8y146	230	4	FigTree	FigTree	NNP
cord-024061-gxv8y146	230	5	provides	provide	VBZ
cord-024061-gxv8y146	230	6	many	many	JJ
cord-024061-gxv8y146	230	7	customizable	customizable	JJ
cord-024061-gxv8y146	230	8	tree	tree	NN
cord-024061-gxv8y146	230	9	visualization	visualization	NN
cord-024061-gxv8y146	230	10	options	option	NNS
cord-024061-gxv8y146	230	11	as	as	RB
cord-024061-gxv8y146	230	12	well	well	RB
cord-024061-gxv8y146	230	13	as	as	IN
cord-024061-gxv8y146	230	14	it	-PRON-	PRP
cord-024061-gxv8y146	230	15	allows	allow	VBZ
cord-024061-gxv8y146	230	16	the	the	DT
cord-024061-gxv8y146	230	17	users	user	NNS
cord-024061-gxv8y146	230	18	to	to	TO
cord-024061-gxv8y146	230	19	upload	upload	VB
cord-024061-gxv8y146	230	20	additional	additional	JJ
cord-024061-gxv8y146	230	21	information	information	NN
cord-024061-gxv8y146	230	22	using	use	VBG
cord-024061-gxv8y146	230	23	a	a	DT
cord-024061-gxv8y146	230	24	text	text	NN
cord-024061-gxv8y146	230	25	file	file	NN
cord-024061-gxv8y146	230	26	to	to	TO
cord-024061-gxv8y146	230	27	annotate	annotate	VB
cord-024061-gxv8y146	230	28	flexibly	flexibly	RB
cord-024061-gxv8y146	230	29	descriptions	description	NNS
cord-024061-gxv8y146	230	30	on	on	IN
cord-024061-gxv8y146	230	31	the	the	DT
cord-024061-gxv8y146	230	32	nodes	node	NNS
cord-024061-gxv8y146	230	33	and	and	CC
cord-024061-gxv8y146	230	34	branches	branch	NNS
cord-024061-gxv8y146	230	35	of	of	IN
cord-024061-gxv8y146	230	36	the	the	DT
cord-024061-gxv8y146	230	37	trees	tree	NNS
cord-024061-gxv8y146	230	38	.	.	.
cord-024061-gxv8y146	231	1	SpreaD3	SpreaD3	NNP
cord-024061-gxv8y146	231	2	is	be	VBZ
cord-024061-gxv8y146	231	3	an	an	DT
cord-024061-gxv8y146	231	4	interactive	interactive	JJ
cord-024061-gxv8y146	231	5	Java	Java	NNP
cord-024061-gxv8y146	231	6	-	-	HYPH
cord-024061-gxv8y146	231	7	based	base	VBN
cord-024061-gxv8y146	231	8	parsing	parsing	NN
cord-024061-gxv8y146	231	9	and	and	CC
cord-024061-gxv8y146	231	10	rendering	rendering	JJ
cord-024061-gxv8y146	231	11	tool	tool	NN
cord-024061-gxv8y146	231	12	that	that	WDT
cord-024061-gxv8y146	231	13	can	can	MD
cord-024061-gxv8y146	231	14	summarize	summarize	VB
cord-024061-gxv8y146	231	15	and	and	CC
cord-024061-gxv8y146	231	16	visualize	visualize	VB
cord-024061-gxv8y146	231	17	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	231	18	reconstructions	reconstruction	NNS
cord-024061-gxv8y146	231	19	to	to	TO
cord-024061-gxv8y146	231	20	infer	infer	VB
cord-024061-gxv8y146	231	21	spatio	spatio	JJ
cord-024061-gxv8y146	231	22	-	-	HYPH
cord-024061-gxv8y146	231	23	temporal	temporal	JJ
cord-024061-gxv8y146	231	24	and	and	CC
cord-024061-gxv8y146	231	25	trait	trait	NN
cord-024061-gxv8y146	231	26	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	231	27	history	history	NN
cord-024061-gxv8y146	231	28	(	(	-LRB-
cord-024061-gxv8y146	231	29	114	114	CD
cord-024061-gxv8y146	231	30	)	)	-RRB-
cord-024061-gxv8y146	231	31	.	.	.
cord-024061-gxv8y146	232	1	Also	also	RB
cord-024061-gxv8y146	232	2	,	,	,
cord-024061-gxv8y146	232	3	SpreaD3	SpreaD3	NNP
cord-024061-gxv8y146	232	4	integrates	integrate	VBZ
cord-024061-gxv8y146	232	5	JavaScript	JavaScript	NNP
cord-024061-gxv8y146	232	6	D3	D3	NNP
cord-024061-gxv8y146	232	7	libraries	library	NNS
cord-024061-gxv8y146	232	8	to	to	TO
cord-024061-gxv8y146	232	9	provide	provide	VB
cord-024061-gxv8y146	232	10	a	a	DT
cord-024061-gxv8y146	232	11	web	web	NN
cord-024061-gxv8y146	232	12	-	-	HYPH
cord-024061-gxv8y146	232	13	based	base	VBN
cord-024061-gxv8y146	232	14	visualization	visualization	NN
cord-024061-gxv8y146	232	15	platform	platform	NN
cord-024061-gxv8y146	232	16	for	for	IN
cord-024061-gxv8y146	232	17	phylogeographic	phylogeographic	JJ
cord-024061-gxv8y146	232	18	trees	tree	NNS
cord-024061-gxv8y146	232	19	and	and	CC
cord-024061-gxv8y146	232	20	their	-PRON-	PRP$
cord-024061-gxv8y146	232	21	related	related	JJ
cord-024061-gxv8y146	232	22	inferences	inference	NNS
cord-024061-gxv8y146	232	23	by	by	IN
cord-024061-gxv8y146	232	24	combining	combine	VBG
cord-024061-gxv8y146	232	25	information	information	NN
cord-024061-gxv8y146	232	26	from	from	IN
cord-024061-gxv8y146	232	27	the	the	DT
cord-024061-gxv8y146	232	28	MCC	MCC	NNP
cord-024061-gxv8y146	232	29	tree	tree	NN
cord-024061-gxv8y146	232	30	and	and	CC
cord-024061-gxv8y146	232	31	GeoJSON	geojson	NN
cord-024061-gxv8y146	232	32	-	-	HYPH
cord-024061-gxv8y146	232	33	based	base	VBN
cord-024061-gxv8y146	232	34	geographic	geographic	JJ
cord-024061-gxv8y146	232	35	map	map	NN
cord-024061-gxv8y146	232	36	files	file	NNS
cord-024061-gxv8y146	232	37	(	(	-LRB-
cord-024061-gxv8y146	232	38	114	114	CD
cord-024061-gxv8y146	232	39	)	)	-RRB-
cord-024061-gxv8y146	232	40	.	.	.
cord-024061-gxv8y146	233	1	SpreaD3	SpreaD3	NNP
cord-024061-gxv8y146	233	2	can	can	MD
cord-024061-gxv8y146	233	3	generate	generate	VB
cord-024061-gxv8y146	233	4	a	a	DT
cord-024061-gxv8y146	233	5	time	time	NN
cord-024061-gxv8y146	233	6	-	-	HYPH
cord-024061-gxv8y146	233	7	lapse	lapse	NN
cord-024061-gxv8y146	233	8	that	that	WDT
cord-024061-gxv8y146	233	9	superimposes	superimpose	VBZ
cord-024061-gxv8y146	233	10	the	the	DT
cord-024061-gxv8y146	233	11	MCC	MCC	NNP
cord-024061-gxv8y146	233	12	tree	tree	NN
cord-024061-gxv8y146	233	13	annotated	annotate	VBN
cord-024061-gxv8y146	233	14	with	with	IN
cord-024061-gxv8y146	233	15	either	either	DT
cord-024061-gxv8y146	233	16	discrete	discrete	JJ
cord-024061-gxv8y146	233	17	or	or	CC
cord-024061-gxv8y146	233	18	continuous	continuous	JJ
cord-024061-gxv8y146	233	19	spatial	spatial	JJ
cord-024061-gxv8y146	233	20	traits	trait	NNS
cord-024061-gxv8y146	233	21	on	on	IN
cord-024061-gxv8y146	233	22	a	a	DT
cord-024061-gxv8y146	233	23	map	map	NN
cord-024061-gxv8y146	233	24	,	,	,
cord-024061-gxv8y146	233	25	which	which	WDT
cord-024061-gxv8y146	233	26	can	can	MD
cord-024061-gxv8y146	233	27	be	be	VB
cord-024061-gxv8y146	233	28	visualized	visualize	VBN
cord-024061-gxv8y146	233	29	using	use	VBG
cord-024061-gxv8y146	233	30	either	either	CC
cord-024061-gxv8y146	233	31	GIS	GIS	NNP
cord-024061-gxv8y146	233	32	-	-	HYPH
cord-024061-gxv8y146	233	33	KLM	KLM	NNP
cord-024061-gxv8y146	233	34	virtual	virtual	JJ
cord-024061-gxv8y146	233	35	globe	globe	NN
cord-024061-gxv8y146	233	36	software	software	NN
cord-024061-gxv8y146	233	37	(	(	-LRB-
cord-024061-gxv8y146	233	38	e.g.	e.g.	RB
cord-024061-gxv8y146	233	39	,	,	,
cord-024061-gxv8y146	233	40	Google	Google	NNP
cord-024061-gxv8y146	233	41	Earth	Earth	NNP
cord-024061-gxv8y146	233	42	)	)	-RRB-
cord-024061-gxv8y146	233	43	or	or	CC
cord-024061-gxv8y146	233	44	modern	modern	JJ
cord-024061-gxv8y146	233	45	web	web	NN
cord-024061-gxv8y146	233	46	-	-	HYPH
cord-024061-gxv8y146	233	47	browsers	browser	NNS
cord-024061-gxv8y146	233	48	(	(	-LRB-
cord-024061-gxv8y146	233	49	e.g.	e.g.	RB
cord-024061-gxv8y146	233	50	,	,	,
cord-024061-gxv8y146	233	51	Safari	Safari	NNP
cord-024061-gxv8y146	233	52	or	or	CC
cord-024061-gxv8y146	233	53	Chrome	Chrome	NNP
cord-024061-gxv8y146	233	54	)	)	-RRB-
cord-024061-gxv8y146	233	55	.	.	.
cord-024061-gxv8y146	234	1	This	this	DT
cord-024061-gxv8y146	234	2	time	time	NN
cord-024061-gxv8y146	234	3	-	-	HYPH
cord-024061-gxv8y146	234	4	lapse	lapse	NN
cord-024061-gxv8y146	234	5	demonstrates	demonstrate	VBZ
cord-024061-gxv8y146	234	6	the	the	DT
cord-024061-gxv8y146	234	7	epidemic	epidemic	NN
cord-024061-gxv8y146	234	8	reconstruction	reconstruction	NN
cord-024061-gxv8y146	234	9	of	of	IN
cord-024061-gxv8y146	234	10	pathogen	pathogen	NN
cord-024061-gxv8y146	234	11	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	234	12	history	history	NN
cord-024061-gxv8y146	234	13	through	through	IN
cord-024061-gxv8y146	234	14	space	space	NN
cord-024061-gxv8y146	234	15	and	and	CC
cord-024061-gxv8y146	234	16	time	time	NN
cord-024061-gxv8y146	234	17	,	,	,
cord-024061-gxv8y146	234	18	which	which	WDT
cord-024061-gxv8y146	234	19	can	can	MD
cord-024061-gxv8y146	234	20	quantify	quantify	VB
cord-024061-gxv8y146	234	21	the	the	DT
cord-024061-gxv8y146	234	22	diffusion	diffusion	NN
cord-024061-gxv8y146	234	23	processes	process	NNS
cord-024061-gxv8y146	234	24	within	within	IN
cord-024061-gxv8y146	234	25	and	and	CC
cord-024061-gxv8y146	234	26	between	between	IN
cord-024061-gxv8y146	234	27	geographical	geographical	JJ
cord-024061-gxv8y146	234	28	regions	region	NNS
cord-024061-gxv8y146	234	29	.	.	.
cord-024061-gxv8y146	235	1	Furthermore	furthermore	RB
cord-024061-gxv8y146	235	2	,	,	,
cord-024061-gxv8y146	235	3	SpreaD3	SpreaD3	''
cord-024061-gxv8y146	235	4	can	can	MD
cord-024061-gxv8y146	235	5	identify	identify	VB
cord-024061-gxv8y146	235	6	and	and	CC
cord-024061-gxv8y146	235	7	plot	plot	VB
cord-024061-gxv8y146	235	8	well	well	RB
cord-024061-gxv8y146	235	9	-	-	HYPH
cord-024061-gxv8y146	235	10	supported	support	VBN
cord-024061-gxv8y146	235	11	rates	rate	NNS
cord-024061-gxv8y146	235	12	between	between	IN
cord-024061-gxv8y146	235	13	pairs	pair	NNS
cord-024061-gxv8y146	235	14	of	of	IN
cord-024061-gxv8y146	235	15	discrete	discrete	JJ
cord-024061-gxv8y146	235	16	traits	trait	NNS
cord-024061-gxv8y146	235	17	using	use	VBG
cord-024061-gxv8y146	235	18	BFs	BFs	NNP
cord-024061-gxv8y146	235	19	estimated	estimate	VBN
cord-024061-gxv8y146	235	20	from	from	IN
cord-024061-gxv8y146	235	21	the	the	DT
cord-024061-gxv8y146	235	22	symmetric	symmetric	JJ
cord-024061-gxv8y146	235	23	or	or	CC
cord-024061-gxv8y146	235	24	the	the	DT
cord-024061-gxv8y146	235	25	asymmetric	asymmetric	JJ
cord-024061-gxv8y146	235	26	BSSVS	BSSVS	NNP
cord-024061-gxv8y146	235	27	models	model	NNS
cord-024061-gxv8y146	235	28	.	.	.
cord-024061-gxv8y146	236	1	Statistically	statistically	RB
cord-024061-gxv8y146	236	2	significant	significant	JJ
cord-024061-gxv8y146	236	3	rates	rate	NNS
cord-024061-gxv8y146	236	4	with	with	IN
cord-024061-gxv8y146	236	5	large	large	JJ
cord-024061-gxv8y146	236	6	BF	bf	NN
cord-024061-gxv8y146	236	7	values	value	NNS
cord-024061-gxv8y146	236	8	can	can	MD
cord-024061-gxv8y146	236	9	be	be	VB
cord-024061-gxv8y146	236	10	used	use	VBN
cord-024061-gxv8y146	236	11	to	to	TO
cord-024061-gxv8y146	236	12	demonstrate	demonstrate	VB
cord-024061-gxv8y146	236	13	critical	critical	JJ
cord-024061-gxv8y146	236	14	viral	viral	JJ
cord-024061-gxv8y146	236	15	dispersal	dispersal	NN
cord-024061-gxv8y146	236	16	routes	route	NNS
cord-024061-gxv8y146	236	17	between	between	IN
cord-024061-gxv8y146	236	18	geographical	geographical	JJ
cord-024061-gxv8y146	236	19	regions	region	NNS
cord-024061-gxv8y146	236	20	or	or	CC
cord-024061-gxv8y146	236	21	transmission	transmission	NN
cord-024061-gxv8y146	236	22	cycles	cycle	NNS
cord-024061-gxv8y146	236	23	between	between	IN
cord-024061-gxv8y146	236	24	host	host	NN
cord-024061-gxv8y146	236	25	species	specie	NNS
cord-024061-gxv8y146	236	26	.	.	.
cord-024061-gxv8y146	237	1	The	the	DT
cord-024061-gxv8y146	237	2	spillover	spillover	NN
cord-024061-gxv8y146	237	3	of	of	IN
cord-024061-gxv8y146	237	4	H3	H3	NNP
cord-024061-gxv8y146	237	5	SI	SI	NNP
cord-024061-gxv8y146	237	6	virus	virus	NN
cord-024061-gxv8y146	237	7	from	from	IN
cord-024061-gxv8y146	237	8	humans	human	NNS
cord-024061-gxv8y146	237	9	to	to	IN
cord-024061-gxv8y146	237	10	swine	swine	NN
cord-024061-gxv8y146	237	11	in	in	IN
cord-024061-gxv8y146	237	12	the	the	DT
cord-024061-gxv8y146	237	13	early	early	JJ
cord-024061-gxv8y146	237	14	2010s	2010	NNS
cord-024061-gxv8y146	237	15	in	in	IN
cord-024061-gxv8y146	237	16	the	the	DT
cord-024061-gxv8y146	237	17	United	United	NNP
cord-024061-gxv8y146	237	18	States	States	NNP
cord-024061-gxv8y146	237	19	resulted	result	VBD
cord-024061-gxv8y146	237	20	in	in	IN
cord-024061-gxv8y146	237	21	a	a	DT
cord-024061-gxv8y146	237	22	novel	novel	JJ
cord-024061-gxv8y146	237	23	emerging	emerge	VBG
cord-024061-gxv8y146	237	24	virulent	virulent	JJ
cord-024061-gxv8y146	237	25	strain	strain	NN
cord-024061-gxv8y146	237	26	,	,	,
cord-024061-gxv8y146	237	27	which	which	WDT
cord-024061-gxv8y146	237	28	was	be	VBD
cord-024061-gxv8y146	237	29	antigenically	antigenically	RB
cord-024061-gxv8y146	237	30	distinct	distinct	JJ
cord-024061-gxv8y146	237	31	from	from	IN
cord-024061-gxv8y146	237	32	endemic	endemic	JJ
cord-024061-gxv8y146	237	33	swine	swine	NN
cord-024061-gxv8y146	237	34	strains	strain	NNS
cord-024061-gxv8y146	237	35	,	,	,
cord-024061-gxv8y146	237	36	and	and	CC
cord-024061-gxv8y146	237	37	therefore	therefore	RB
cord-024061-gxv8y146	237	38	was	be	VBD
cord-024061-gxv8y146	237	39	named	name	VBN
cord-024061-gxv8y146	237	40	"	"	``
cord-024061-gxv8y146	237	41	human	human	NN
cord-024061-gxv8y146	237	42	-	-	HYPH
cord-024061-gxv8y146	237	43	like	like	JJ
cord-024061-gxv8y146	237	44	"	"	``
cord-024061-gxv8y146	237	45	H3	H3	NNP
cord-024061-gxv8y146	237	46	virus	virus	NN
cord-024061-gxv8y146	237	47	(	(	-LRB-
cord-024061-gxv8y146	237	48	115	115	CD
cord-024061-gxv8y146	237	49	)	)	-RRB-
cord-024061-gxv8y146	237	50	.	.	.
cord-024061-gxv8y146	238	1	Swine	swine	NN
cord-024061-gxv8y146	238	2	-	-	HYPH
cord-024061-gxv8y146	238	3	related	relate	VBN
cord-024061-gxv8y146	238	4	anthropological	anthropological	JJ
cord-024061-gxv8y146	238	5	activities	activity	NNS
cord-024061-gxv8y146	238	6	such	such	JJ
cord-024061-gxv8y146	238	7	as	as	IN
cord-024061-gxv8y146	238	8	pig	pig	NN
cord-024061-gxv8y146	238	9	movement	movement	NN
cord-024061-gxv8y146	238	10	and	and	CC
cord-024061-gxv8y146	238	11	vaccination	vaccination	NN
cord-024061-gxv8y146	238	12	are	be	VBP
cord-024061-gxv8y146	238	13	the	the	DT
cord-024061-gxv8y146	238	14	most	most	RBS
cord-024061-gxv8y146	238	15	likely	likely	JJ
cord-024061-gxv8y146	238	16	factors	factor	NNS
cord-024061-gxv8y146	238	17	for	for	IN
cord-024061-gxv8y146	238	18	the	the	DT
cord-024061-gxv8y146	238	19	continuous	continuous	JJ
cord-024061-gxv8y146	238	20	emergence	emergence	NN
cord-024061-gxv8y146	238	21	of	of	IN
cord-024061-gxv8y146	238	22	SI	SI	NNP
cord-024061-gxv8y146	238	23	novel	novel	NN
cord-024061-gxv8y146	238	24	strains	strain	NNS
cord-024061-gxv8y146	238	25	(	(	-LRB-
cord-024061-gxv8y146	238	26	6	6	CD
cord-024061-gxv8y146	238	27	)	)	-RRB-
cord-024061-gxv8y146	238	28	.	.	.
cord-024061-gxv8y146	239	1	Therefore	therefore	RB
cord-024061-gxv8y146	239	2	,	,	,
cord-024061-gxv8y146	239	3	integrating	integrate	VBG
cord-024061-gxv8y146	239	4	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	239	5	methods	method	NNS
cord-024061-gxv8y146	239	6	with	with	IN
cord-024061-gxv8y146	239	7	influenza	influenza	NN
cord-024061-gxv8y146	239	8	surveillance	surveillance	NN
cord-024061-gxv8y146	239	9	systems	system	NNS
cord-024061-gxv8y146	239	10	may	may	MD
cord-024061-gxv8y146	239	11	reduce	reduce	VB
cord-024061-gxv8y146	239	12	the	the	DT
cord-024061-gxv8y146	239	13	continuous	continuous	JJ
cord-024061-gxv8y146	239	14	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	239	15	implications	implication	NNS
cord-024061-gxv8y146	239	16	of	of	IN
cord-024061-gxv8y146	239	17	SI	SI	NNP
cord-024061-gxv8y146	239	18	viruses	virus	NNS
cord-024061-gxv8y146	239	19	on	on	IN
cord-024061-gxv8y146	239	20	both	both	DT
cord-024061-gxv8y146	239	21	public	public	JJ
cord-024061-gxv8y146	239	22	and	and	CC
cord-024061-gxv8y146	239	23	animal	animal	NN
cord-024061-gxv8y146	239	24	health	health	NN
cord-024061-gxv8y146	239	25	in	in	IN
cord-024061-gxv8y146	239	26	the	the	DT
cord-024061-gxv8y146	239	27	United	United	NNP
cord-024061-gxv8y146	239	28	States	States	NNP
cord-024061-gxv8y146	239	29	and	and	CC
cord-024061-gxv8y146	239	30	worldwide	worldwide	RB
cord-024061-gxv8y146	239	31	.	.	.
cord-024061-gxv8y146	240	1	Here	here	RB
cord-024061-gxv8y146	240	2	,	,	,
cord-024061-gxv8y146	240	3	we	-PRON-	PRP
cord-024061-gxv8y146	240	4	chose	choose	VBD
cord-024061-gxv8y146	240	5	DTA	DTA	NNP
cord-024061-gxv8y146	240	6	models	model	NNS
cord-024061-gxv8y146	240	7	for	for	IN
cord-024061-gxv8y146	240	8	our	-PRON-	PRP$
cord-024061-gxv8y146	240	9	comparative	comparative	JJ
cord-024061-gxv8y146	240	10	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	240	11	analyses	analysis	NNS
cord-024061-gxv8y146	240	12	example	example	NN
cord-024061-gxv8y146	240	13	,	,	,
cord-024061-gxv8y146	240	14	due	due	IN
cord-024061-gxv8y146	240	15	to	to	IN
cord-024061-gxv8y146	240	16	their	-PRON-	PRP$
cord-024061-gxv8y146	240	17	popularity	popularity	NN
cord-024061-gxv8y146	240	18	,	,	,
cord-024061-gxv8y146	240	19	ease	ease	NN
cord-024061-gxv8y146	240	20	of	of	IN
cord-024061-gxv8y146	240	21	use	use	NN
cord-024061-gxv8y146	240	22	,	,	,
cord-024061-gxv8y146	240	23	interpretation	interpretation	NN
cord-024061-gxv8y146	240	24	,	,	,
cord-024061-gxv8y146	240	25	and	and	CC
cord-024061-gxv8y146	240	26	computational	computational	JJ
cord-024061-gxv8y146	240	27	efficiency	efficiency	NN
cord-024061-gxv8y146	240	28	when	when	WRB
cord-024061-gxv8y146	240	29	compared	compare	VBN
cord-024061-gxv8y146	240	30	to	to	IN
cord-024061-gxv8y146	240	31	more	more	RBR
cord-024061-gxv8y146	240	32	complex	complex	JJ
cord-024061-gxv8y146	240	33	similar	similar	JJ
cord-024061-gxv8y146	240	34	models	model	NNS
cord-024061-gxv8y146	240	35	.	.	.
cord-024061-gxv8y146	241	1	Hence	hence	RB
cord-024061-gxv8y146	241	2	,	,	,
cord-024061-gxv8y146	241	3	we	-PRON-	PRP
cord-024061-gxv8y146	241	4	retrieved	retrieve	VBD
cord-024061-gxv8y146	241	5	HA	HA	NNP
cord-024061-gxv8y146	241	6	and	and	CC
cord-024061-gxv8y146	241	7	PB2	PB2	NNP
cord-024061-gxv8y146	241	8	nucleotide	nucleotide	JJ
cord-024061-gxv8y146	241	9	sequences	sequence	NNS
cord-024061-gxv8y146	241	10	of	of	IN
cord-024061-gxv8y146	241	11	human	human	NN
cord-024061-gxv8y146	241	12	-	-	HYPH
cord-024061-gxv8y146	241	13	like	like	JJ
cord-024061-gxv8y146	241	14	H3	H3	NNP
cord-024061-gxv8y146	241	15	SI	SI	NNP
cord-024061-gxv8y146	241	16	from	from	IN
cord-024061-gxv8y146	241	17	the	the	DT
cord-024061-gxv8y146	241	18	Influenza	Influenza	NNP
cord-024061-gxv8y146	241	19	Research	Research	NNP
cord-024061-gxv8y146	241	20	Database	Database	NNP
cord-024061-gxv8y146	241	21	(	(	-LRB-
cord-024061-gxv8y146	241	22	116	116	CD
cord-024061-gxv8y146	241	23	)	)	-RRB-
cord-024061-gxv8y146	241	24	to	to	TO
cord-024061-gxv8y146	241	25	explore	explore	VB
cord-024061-gxv8y146	241	26	their	-PRON-	PRP$
cord-024061-gxv8y146	241	27	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	241	28	history	history	NN
cord-024061-gxv8y146	241	29	using	use	VBG
cord-024061-gxv8y146	241	30	our	-PRON-	PRP$
cord-024061-gxv8y146	241	31	suggested	suggest	VBN
cord-024061-gxv8y146	241	32	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	241	33	pipeline	pipeline	NN
cord-024061-gxv8y146	241	34	,	,	,
cord-024061-gxv8y146	241	35	described	describe	VBN
cord-024061-gxv8y146	241	36	above	above	IN
cord-024061-gxv8y146	241	37	(	(	-LRB-
cord-024061-gxv8y146	241	38	Figure	figure	NN
cord-024061-gxv8y146	241	39	1	1	CD
cord-024061-gxv8y146	241	40	)	)	-RRB-
cord-024061-gxv8y146	241	41	.	.	.
cord-024061-gxv8y146	242	1	The	the	DT
cord-024061-gxv8y146	242	2	data	datum	NNS
cord-024061-gxv8y146	242	3	comprised	comprise	VBD
cord-024061-gxv8y146	242	4	352	352	CD
cord-024061-gxv8y146	242	5	sequences	sequence	NNS
cord-024061-gxv8y146	242	6	with	with	IN
cord-024061-gxv8y146	242	7	complete	complete	JJ
cord-024061-gxv8y146	242	8	date	date	NN
cord-024061-gxv8y146	242	9	and	and	CC
cord-024061-gxv8y146	242	10	geographical	geographical	JJ
cord-024061-gxv8y146	242	11	information	information	NN
cord-024061-gxv8y146	242	12	for	for	IN
cord-024061-gxv8y146	242	13	each	each	DT
cord-024061-gxv8y146	242	14	gene	gene	NN
cord-024061-gxv8y146	242	15	segment	segment	NN
cord-024061-gxv8y146	242	16	and	and	CC
cord-024061-gxv8y146	242	17	was	be	VBD
cord-024061-gxv8y146	242	18	collected	collect	VBN
cord-024061-gxv8y146	242	19	from	from	IN
cord-024061-gxv8y146	242	20	17	17	CD
cord-024061-gxv8y146	242	21	U.S.	U.S.	NNP
cord-024061-gxv8y146	242	22	states	state	NNS
cord-024061-gxv8y146	242	23	(	(	-LRB-
cord-024061-gxv8y146	242	24	Arkansas	Arkansas	NNP
cord-024061-gxv8y146	242	25	,	,	,
cord-024061-gxv8y146	242	26	Illinois	Illinois	NNP
cord-024061-gxv8y146	242	27	,	,	,
cord-024061-gxv8y146	242	28	Indiana	Indiana	NNP
cord-024061-gxv8y146	242	29	,	,	,
cord-024061-gxv8y146	242	30	Iowa	Iowa	NNP
cord-024061-gxv8y146	242	31	,	,	,
cord-024061-gxv8y146	242	32	Kentucky	Kentucky	NNP
cord-024061-gxv8y146	242	33	,	,	,
cord-024061-gxv8y146	242	34	Maryland	Maryland	NNP
cord-024061-gxv8y146	242	35	,	,	,
cord-024061-gxv8y146	242	36	Michigan	Michigan	NNP
cord-024061-gxv8y146	242	37	,	,	,
cord-024061-gxv8y146	242	38	Minnesota	Minnesota	NNP
cord-024061-gxv8y146	242	39	,	,	,
cord-024061-gxv8y146	242	40	Missouri	Missouri	NNP
cord-024061-gxv8y146	242	41	,	,	,
cord-024061-gxv8y146	242	42	North	North	NNP
cord-024061-gxv8y146	242	43	Carolina	Carolina	NNP
cord-024061-gxv8y146	242	44	,	,	,
cord-024061-gxv8y146	242	45	Ohio	Ohio	NNP
cord-024061-gxv8y146	242	46	,	,	,
cord-024061-gxv8y146	242	47	Oklahoma	Oklahoma	NNP
cord-024061-gxv8y146	242	48	,	,	,
cord-024061-gxv8y146	242	49	Oregon	Oregon	NNP
cord-024061-gxv8y146	242	50	,	,	,
cord-024061-gxv8y146	242	51	Pennsylvania	Pennsylvania	NNP
cord-024061-gxv8y146	242	52	,	,	,
cord-024061-gxv8y146	242	53	South	South	NNP
cord-024061-gxv8y146	242	54	Dakota	Dakota	NNP
cord-024061-gxv8y146	242	55	,	,	,
cord-024061-gxv8y146	242	56	West	West	NNP
cord-024061-gxv8y146	242	57	Virginia	Virginia	NNP
cord-024061-gxv8y146	242	58	,	,	,
cord-024061-gxv8y146	242	59	Wisconsin	Wisconsin	NNP
cord-024061-gxv8y146	242	60	)	)	-RRB-
cord-024061-gxv8y146	242	61	between	between	IN
cord-024061-gxv8y146	242	62	January	January	NNP
cord-024061-gxv8y146	242	63	8	8	CD
cord-024061-gxv8y146	242	64	,	,	,
cord-024061-gxv8y146	242	65	2015	2015	CD
cord-024061-gxv8y146	242	66	and	and	CC
cord-024061-gxv8y146	242	67	June	June	NNP
cord-024061-gxv8y146	242	68	1	1	CD
cord-024061-gxv8y146	242	69	,	,	,
cord-024061-gxv8y146	242	70	2018	2018	CD
cord-024061-gxv8y146	242	71	.	.	.
cord-024061-gxv8y146	243	1	The	the	DT
cord-024061-gxv8y146	243	2	sequence	sequence	NN
cord-024061-gxv8y146	243	3	data	datum	NNS
cord-024061-gxv8y146	243	4	were	be	VBD
cord-024061-gxv8y146	243	5	collected	collect	VBN
cord-024061-gxv8y146	243	6	from	from	IN
cord-024061-gxv8y146	243	7	the	the	DT
cord-024061-gxv8y146	243	8	swine	swine	NN
cord-024061-gxv8y146	243	9	production	production	NN
cord-024061-gxv8y146	243	10	systems	system	NNS
cord-024061-gxv8y146	243	11	and	and	CC
cord-024061-gxv8y146	243	12	exhibition	exhibition	NN
cord-024061-gxv8y146	243	13	swine	swine	NN
cord-024061-gxv8y146	243	14	agricultural	agricultural	JJ
cord-024061-gxv8y146	243	15	state	state	NN
cord-024061-gxv8y146	243	16	fairs	fair	NNS
cord-024061-gxv8y146	243	17	as	as	IN
cord-024061-gxv8y146	243	18	part	part	NN
cord-024061-gxv8y146	243	19	of	of	IN
cord-024061-gxv8y146	243	20	the	the	DT
cord-024061-gxv8y146	243	21	United	United	NNP
cord-024061-gxv8y146	243	22	States	States	NNP
cord-024061-gxv8y146	243	23	Department	Department	NNP
cord-024061-gxv8y146	243	24	of	of	IN
cord-024061-gxv8y146	243	25	Agriculture	Agriculture	NNP
cord-024061-gxv8y146	243	26	(	(	-LRB-
cord-024061-gxv8y146	243	27	USDA	USDA	NNP
cord-024061-gxv8y146	243	28	)	)	-RRB-
cord-024061-gxv8y146	243	29	swine	swine	NNP
cord-024061-gxv8y146	243	30	influenza	influenza	NNP
cord-024061-gxv8y146	243	31	surveillance	surveillance	NN
cord-024061-gxv8y146	243	32	program	program	NN
cord-024061-gxv8y146	243	33	(	(	-LRB-
cord-024061-gxv8y146	243	34	40	40	CD
cord-024061-gxv8y146	243	35	)	)	-RRB-
cord-024061-gxv8y146	243	36	and	and	CC
cord-024061-gxv8y146	243	37	was	be	VBD
cord-024061-gxv8y146	243	38	partially	partially	RB
cord-024061-gxv8y146	243	39	analyzed	analyze	VBN
cord-024061-gxv8y146	243	40	by	by	IN
cord-024061-gxv8y146	243	41	Walia	Walia	NNP
cord-024061-gxv8y146	243	42	et	et	NNP
cord-024061-gxv8y146	243	43	al	al	NNP
cord-024061-gxv8y146	243	44	.	.	.
cord-024061-gxv8y146	244	1	using	use	VBG
cord-024061-gxv8y146	244	2	classical	classical	JJ
cord-024061-gxv8y146	244	3	phylogenetic	phylogenetic	JJ
cord-024061-gxv8y146	244	4	methods	method	NNS
cord-024061-gxv8y146	244	5	(	(	-LRB-
cord-024061-gxv8y146	244	6	6	6	CD
cord-024061-gxv8y146	244	7	)	)	-RRB-
cord-024061-gxv8y146	244	8	.	.	.
cord-024061-gxv8y146	245	1	We	-PRON-	PRP
cord-024061-gxv8y146	245	2	aligned	align	VBD
cord-024061-gxv8y146	245	3	the	the	DT
cord-024061-gxv8y146	245	4	sequences	sequence	NNS
cord-024061-gxv8y146	245	5	for	for	IN
cord-024061-gxv8y146	245	6	both	both	DT
cord-024061-gxv8y146	245	7	gene	gene	NN
cord-024061-gxv8y146	245	8	segments	segment	NNS
cord-024061-gxv8y146	245	9	and	and	CC
cord-024061-gxv8y146	245	10	assessed	assess	VBD
cord-024061-gxv8y146	245	11	the	the	DT
cord-024061-gxv8y146	245	12	topological	topological	JJ
cord-024061-gxv8y146	245	13	(	(	-LRB-
cord-024061-gxv8y146	245	14	in)congruence	in)congruence	NN
cord-024061-gxv8y146	245	15	of	of	IN
cord-024061-gxv8y146	245	16	their	-PRON-	PRP$
cord-024061-gxv8y146	245	17	phylogeny	phylogeny	NN
cord-024061-gxv8y146	245	18	by	by	IN
cord-024061-gxv8y146	245	19	performing	perform	VBG
cord-024061-gxv8y146	245	20	an	an	DT
cord-024061-gxv8y146	245	21	ML	ML	NNP
cord-024061-gxv8y146	245	22	analysis	analysis	NN
cord-024061-gxv8y146	245	23	for	for	IN
cord-024061-gxv8y146	245	24	the	the	DT
cord-024061-gxv8y146	245	25	individual	individual	JJ
cord-024061-gxv8y146	245	26	segments	segment	NNS
cord-024061-gxv8y146	245	27	using	use	VBG
cord-024061-gxv8y146	245	28	the	the	DT
cord-024061-gxv8y146	245	29	GTR	GTR	NNP
cord-024061-gxv8y146	245	30	+	+	SYM
cord-024061-gxv8y146	245	31	Ŵ	ŵ	CD
cord-024061-gxv8y146	245	32	substitution	substitution	NN
cord-024061-gxv8y146	245	33	model	model	NN
cord-024061-gxv8y146	245	34	,	,	,
cord-024061-gxv8y146	245	35	which	which	WDT
cord-024061-gxv8y146	245	36	entailed	entail	VBD
cord-024061-gxv8y146	245	37	10	10	CD
cord-024061-gxv8y146	245	38	through	through	IN
cord-024061-gxv8y146	245	39	bootstrap	bootstrap	NN
cord-024061-gxv8y146	245	40	searches	search	NNS
cord-024061-gxv8y146	245	41	with	with	IN
cord-024061-gxv8y146	245	42	100	100	CD
cord-024061-gxv8y146	245	43	ML	ML	NNP
cord-024061-gxv8y146	245	44	replicates	replicate	NNS
cord-024061-gxv8y146	245	45	in	in	IN
cord-024061-gxv8y146	245	46	each	each	DT
cord-024061-gxv8y146	245	47	run	run	NN
cord-024061-gxv8y146	245	48	(	(	-LRB-
cord-024061-gxv8y146	245	49	Supplementary	Supplementary	NNP
cord-024061-gxv8y146	245	50	Figure	figure	NN
cord-024061-gxv8y146	245	51	1	1	CD
cord-024061-gxv8y146	245	52	)	)	-RRB-
cord-024061-gxv8y146	245	53	.	.	.
cord-024061-gxv8y146	246	1	For	for	IN
cord-024061-gxv8y146	246	2	the	the	DT
cord-024061-gxv8y146	246	3	subsequent	subsequent	JJ
cord-024061-gxv8y146	246	4	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	246	5	analyses	analysis	NNS
cord-024061-gxv8y146	246	6	,	,	,
cord-024061-gxv8y146	246	7	we	-PRON-	PRP
cord-024061-gxv8y146	246	8	removed	remove	VBD
cord-024061-gxv8y146	246	9	recombinant	recombinant	JJ
cord-024061-gxv8y146	246	10	and	and	CC
cord-024061-gxv8y146	246	11	100	100	CD
cord-024061-gxv8y146	246	12	%	%	NN
cord-024061-gxv8y146	246	13	identical	identical	JJ
cord-024061-gxv8y146	246	14	sequences	sequence	NNS
cord-024061-gxv8y146	246	15	,	,	,
cord-024061-gxv8y146	246	16	which	which	WDT
cord-024061-gxv8y146	246	17	reduced	reduce	VBD
cord-024061-gxv8y146	246	18	the	the	DT
cord-024061-gxv8y146	246	19	dataset	dataset	NN
cord-024061-gxv8y146	246	20	to	to	IN
cord-024061-gxv8y146	246	21	142	142	CD
cord-024061-gxv8y146	246	22	sequences	sequence	NNS
cord-024061-gxv8y146	246	23	for	for	IN
cord-024061-gxv8y146	246	24	each	each	DT
cord-024061-gxv8y146	246	25	gene	gene	NN
cord-024061-gxv8y146	246	26	segment	segment	NN
cord-024061-gxv8y146	246	27	(	(	-LRB-
cord-024061-gxv8y146	246	28	Supplementary	Supplementary	NNP
cord-024061-gxv8y146	246	29	Table	Table	NNP
cord-024061-gxv8y146	246	30	1	1	CD
cord-024061-gxv8y146	246	31	)	)	-RRB-
cord-024061-gxv8y146	246	32	.	.	.
cord-024061-gxv8y146	247	1	We	-PRON-	PRP
cord-024061-gxv8y146	247	2	then	then	RB
cord-024061-gxv8y146	247	3	evaluated	evaluate	VBD
cord-024061-gxv8y146	247	4	the	the	DT
cord-024061-gxv8y146	247	5	fit	fit	NN
cord-024061-gxv8y146	247	6	of	of	IN
cord-024061-gxv8y146	247	7	the	the	DT
cord-024061-gxv8y146	247	8	sequences	sequence	NNS
cord-024061-gxv8y146	247	9	to	to	IN
cord-024061-gxv8y146	247	10	the	the	DT
cord-024061-gxv8y146	247	11	most	most	RBS
cord-024061-gxv8y146	247	12	realistic	realistic	JJ
cord-024061-gxv8y146	247	13	substitution	substitution	NN
cord-024061-gxv8y146	247	14	model	model	NN
cord-024061-gxv8y146	247	15	and	and	CC
cord-024061-gxv8y146	247	16	partitioning	partitioning	NN
cord-024061-gxv8y146	247	17	scheme	scheme	NN
cord-024061-gxv8y146	247	18	using	use	VBG
cord-024061-gxv8y146	247	19	the	the	DT
cord-024061-gxv8y146	247	20	BIC	BIC	NNP
cord-024061-gxv8y146	247	21	approach	approach	NN
cord-024061-gxv8y146	247	22	.	.	.
cord-024061-gxv8y146	248	1	Finally	finally	RB
cord-024061-gxv8y146	248	2	,	,	,
cord-024061-gxv8y146	248	3	we	-PRON-	PRP
cord-024061-gxv8y146	248	4	evaluated	evaluate	VBD
cord-024061-gxv8y146	248	5	the	the	DT
cord-024061-gxv8y146	248	6	temporal	temporal	JJ
cord-024061-gxv8y146	248	7	signal	signal	NN
cord-024061-gxv8y146	248	8	in	in	IN
cord-024061-gxv8y146	248	9	the	the	DT
cord-024061-gxv8y146	248	10	sequence	sequence	NN
cord-024061-gxv8y146	248	11	data	datum	NNS
cord-024061-gxv8y146	248	12	and	and	CC
cord-024061-gxv8y146	248	13	found	find	VBD
cord-024061-gxv8y146	248	14	that	that	IN
cord-024061-gxv8y146	248	15	both	both	DT
cord-024061-gxv8y146	248	16	segments	segment	NNS
cord-024061-gxv8y146	248	17	were	be	VBD
cord-024061-gxv8y146	248	18	suitable	suitable	JJ
cord-024061-gxv8y146	248	19	for	for	IN
cord-024061-gxv8y146	248	20	the	the	DT
cord-024061-gxv8y146	248	21	subsequent	subsequent	JJ
cord-024061-gxv8y146	248	22	molecular	molecular	JJ
cord-024061-gxv8y146	248	23	clock	clock	NN
cord-024061-gxv8y146	248	24	analyses	analysis	NNS
cord-024061-gxv8y146	248	25	(	(	-LRB-
cord-024061-gxv8y146	248	26	R	r	NN
cord-024061-gxv8y146	248	27	2	2	CD
cord-024061-gxv8y146	248	28	=	=	SYM
cord-024061-gxv8y146	248	29	0.65	0.65	CD
cord-024061-gxv8y146	248	30	and	and	CC
cord-024061-gxv8y146	248	31	0.40	0.40	CD
cord-024061-gxv8y146	248	32	for	for	IN
cord-024061-gxv8y146	248	33	HA	HA	NNP
cord-024061-gxv8y146	248	34	and	and	CC
cord-024061-gxv8y146	248	35	PB2	PB2	NNP
cord-024061-gxv8y146	248	36	,	,	,
cord-024061-gxv8y146	248	37	respectively	respectively	RB
cord-024061-gxv8y146	248	38	)	)	-RRB-
cord-024061-gxv8y146	249	1	(	(	-LRB-
cord-024061-gxv8y146	249	2	Supplementary	Supplementary	NNP
cord-024061-gxv8y146	249	3	Figure	Figure	NNP
cord-024061-gxv8y146	249	4	2	2	CD
cord-024061-gxv8y146	249	5	)	)	-RRB-
cord-024061-gxv8y146	249	6	.	.	.
cord-024061-gxv8y146	250	1	We	-PRON-	PRP
cord-024061-gxv8y146	250	2	assessed	assess	VBD
cord-024061-gxv8y146	250	3	the	the	DT
cord-024061-gxv8y146	250	4	sensitivity	sensitivity	NN
cord-024061-gxv8y146	250	5	of	of	IN
cord-024061-gxv8y146	250	6	the	the	DT
cord-024061-gxv8y146	250	7	inferred	infer	VBN
cord-024061-gxv8y146	250	8	posterior	posterior	JJ
cord-024061-gxv8y146	250	9	evolutionary	evolutionary	NN
cord-024061-gxv8y146	250	10	of	of	IN
cord-024061-gxv8y146	250	11	human	human	NN
cord-024061-gxv8y146	250	12	-	-	HYPH
cord-024061-gxv8y146	250	13	like	like	JJ
cord-024061-gxv8y146	250	14	H3	H3	NNP
cord-024061-gxv8y146	250	15	SI	SI	NNP
cord-024061-gxv8y146	250	16	sequence	sequence	NN
cord-024061-gxv8y146	250	17	data	datum	NNS
cord-024061-gxv8y146	250	18	to	to	IN
cord-024061-gxv8y146	250	19	the	the	DT
cord-024061-gxv8y146	250	20	choice	choice	NN
cord-024061-gxv8y146	250	21	of	of	IN
cord-024061-gxv8y146	250	22	different	different	JJ
cord-024061-gxv8y146	250	23	gene	gene	NN
cord-024061-gxv8y146	250	24	segments	segment	NNS
cord-024061-gxv8y146	250	25	(	(	-LRB-
cord-024061-gxv8y146	250	26	i.e.	i.e.	FW
cord-024061-gxv8y146	250	27	,	,	,
cord-024061-gxv8y146	250	28	HA	HA	NNP
cord-024061-gxv8y146	250	29	vs.	vs.	IN
cord-024061-gxv8y146	250	30	PB2	PB2	NNP
cord-024061-gxv8y146	250	31	)	)	-RRB-
cord-024061-gxv8y146	250	32	and	and	CC
cord-024061-gxv8y146	250	33	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	250	34	priors	prior	NNS
cord-024061-gxv8y146	250	35	,	,	,
cord-024061-gxv8y146	250	36	including	include	VBG
cord-024061-gxv8y146	250	37	substitution	substitution	NN
cord-024061-gxv8y146	250	38	,	,	,
cord-024061-gxv8y146	250	39	discrete	discrete	JJ
cord-024061-gxv8y146	250	40	spatial	spatial	JJ
cord-024061-gxv8y146	250	41	trait	trait	NN
cord-024061-gxv8y146	250	42	,	,	,
cord-024061-gxv8y146	250	43	branch	branch	NN
cord-024061-gxv8y146	250	44	rate	rate	NN
cord-024061-gxv8y146	250	45	,	,	,
cord-024061-gxv8y146	250	46	and	and	CC
cord-024061-gxv8y146	250	47	node	node	NN
cord-024061-gxv8y146	250	48	-	-	HYPH
cord-024061-gxv8y146	250	49	age	age	NN
cord-024061-gxv8y146	250	50	models	model	NNS
cord-024061-gxv8y146	250	51	on	on	IN
cord-024061-gxv8y146	250	52	the	the	DT
cord-024061-gxv8y146	250	53	(	(	-LRB-
cord-024061-gxv8y146	250	54	Figure	figure	NN
cord-024061-gxv8y146	250	55	1	1	CD
cord-024061-gxv8y146	250	56	)	)	-RRB-
cord-024061-gxv8y146	250	57	.	.	.
cord-024061-gxv8y146	251	1	For	for	IN
cord-024061-gxv8y146	251	2	each	each	DT
cord-024061-gxv8y146	251	3	gene	gene	NN
cord-024061-gxv8y146	251	4	segment	segment	NN
cord-024061-gxv8y146	251	5	,	,	,
cord-024061-gxv8y146	251	6	we	-PRON-	PRP
cord-024061-gxv8y146	251	7	generated	generate	VBD
cord-024061-gxv8y146	251	8	16	16	CD
cord-024061-gxv8y146	251	9	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	251	10	models	model	NNS
cord-024061-gxv8y146	251	11	(	(	-LRB-
cord-024061-gxv8y146	251	12	a	a	DT
cord-024061-gxv8y146	251	13	total	total	NN
cord-024061-gxv8y146	251	14	of	of	IN
cord-024061-gxv8y146	251	15	32	32	CD
cord-024061-gxv8y146	251	16	runs	run	NNS
cord-024061-gxv8y146	251	17	for	for	IN
cord-024061-gxv8y146	251	18	both	both	DT
cord-024061-gxv8y146	251	19	segments	segment	NNS
cord-024061-gxv8y146	251	20	)	)	-RRB-
cord-024061-gxv8y146	251	21	using	use	VBG
cord-024061-gxv8y146	251	22	the	the	DT
cord-024061-gxv8y146	251	23	default	default	NN
cord-024061-gxv8y146	251	24	none	none	NN
cord-024061-gxv8y146	251	25	-	-	HYPH
cord-024061-gxv8y146	251	26	informative	informative	JJ
cord-024061-gxv8y146	251	27	priors	prior	NNS
cord-024061-gxv8y146	251	28	'	'	POS
cord-024061-gxv8y146	251	29	combinations	combination	NNS
cord-024061-gxv8y146	251	30	implemented	implement	VBN
cord-024061-gxv8y146	251	31	in	in	IN
cord-024061-gxv8y146	251	32	BEAUTi	BEAUTi	NNP
cord-024061-gxv8y146	251	33	(	(	-LRB-
cord-024061-gxv8y146	251	34	Figure	figure	NN
cord-024061-gxv8y146	251	35	1	1	CD
cord-024061-gxv8y146	251	36	)	)	-RRB-
cord-024061-gxv8y146	251	37	.	.	.
cord-024061-gxv8y146	252	1	These	these	DT
cord-024061-gxv8y146	252	2	prior	prior	JJ
cord-024061-gxv8y146	252	3	models	model	NNS
cord-024061-gxv8y146	252	4	included	include	VBD
cord-024061-gxv8y146	252	5	:	:	:
cord-024061-gxv8y146	252	6	(	(	-LRB-
cord-024061-gxv8y146	252	7	1	1	LS
cord-024061-gxv8y146	252	8	)	)	-RRB-
cord-024061-gxv8y146	252	9	the	the	DT
cord-024061-gxv8y146	252	10	GTR	GTR	NNP
cord-024061-gxv8y146	252	11	+	+	CC
cord-024061-gxv8y146	252	12	Ŵ	ŵ	NN
cord-024061-gxv8y146	252	13	vs.	vs.	IN
cord-024061-gxv8y146	252	14	the	the	DT
cord-024061-gxv8y146	252	15	HKY	HKY	NNP
cord-024061-gxv8y146	252	16	+	+	CC
cord-024061-gxv8y146	252	17	Ŵ	ŵ	NN
cord-024061-gxv8y146	252	18	for	for	IN
cord-024061-gxv8y146	252	19	the	the	DT
cord-024061-gxv8y146	252	20	site	site	NN
cord-024061-gxv8y146	252	21	models	model	NNS
cord-024061-gxv8y146	252	22	;	;	,
cord-024061-gxv8y146	252	23	(	(	-LRB-
cord-024061-gxv8y146	252	24	2	2	LS
cord-024061-gxv8y146	252	25	)	)	-RRB-
cord-024061-gxv8y146	252	26	the	the	DT
cord-024061-gxv8y146	252	27	symmetric	symmetric	JJ
cord-024061-gxv8y146	252	28	vs.	vs.	FW
cord-024061-gxv8y146	252	29	asymmetric	asymmetric	JJ
cord-024061-gxv8y146	252	30	for	for	IN
cord-024061-gxv8y146	252	31	discrete	discrete	JJ
cord-024061-gxv8y146	252	32	spatial	spatial	JJ
cord-024061-gxv8y146	252	33	models	model	NNS
cord-024061-gxv8y146	252	34	;	;	,
cord-024061-gxv8y146	252	35	(	(	-LRB-
cord-024061-gxv8y146	252	36	3	3	LS
cord-024061-gxv8y146	252	37	)	)	-RRB-
cord-024061-gxv8y146	252	38	the	the	DT
cord-024061-gxv8y146	252	39	UCLN	UCLN	NNP
cord-024061-gxv8y146	252	40	vs.	vs.	IN
cord-024061-gxv8y146	252	41	UCED	UCED	NNP
cord-024061-gxv8y146	252	42	for	for	IN
cord-024061-gxv8y146	252	43	the	the	DT
cord-024061-gxv8y146	252	44	clock	clock	NN
cord-024061-gxv8y146	252	45	models	model	NNS
cord-024061-gxv8y146	252	46	;	;	:
cord-024061-gxv8y146	252	47	and	and	CC
cord-024061-gxv8y146	252	48	(	(	-LRB-
cord-024061-gxv8y146	252	49	4	4	LS
cord-024061-gxv8y146	252	50	)	)	-RRB-
cord-024061-gxv8y146	252	51	the	the	DT
cord-024061-gxv8y146	252	52	CP	cp	NN
cord-024061-gxv8y146	252	53	vs.	vs.	FW
cord-024061-gxv8y146	252	54	The	the	DT
cord-024061-gxv8y146	252	55	EG	EG	NNP
cord-024061-gxv8y146	252	56	vs.	vs.	FW
cord-024061-gxv8y146	252	57	The	the	DT
cord-024061-gxv8y146	252	58	EGx	egx	NN
cord-024061-gxv8y146	252	59	vs.	vs.	IN
cord-024061-gxv8y146	252	60	the	the	DT
cord-024061-gxv8y146	252	61	SG	SG	NNP
cord-024061-gxv8y146	252	62	for	for	IN
cord-024061-gxv8y146	252	63	the	the	DT
cord-024061-gxv8y146	252	64	coalescent	coalescent	NN
cord-024061-gxv8y146	252	65	tree	tree	NN
cord-024061-gxv8y146	252	66	models	model	NNS
cord-024061-gxv8y146	252	67	(	(	-LRB-
cord-024061-gxv8y146	252	68	Figure	figure	NN
cord-024061-gxv8y146	252	69	1	1	CD
cord-024061-gxv8y146	252	70	)	)	-RRB-
cord-024061-gxv8y146	252	71	.	.	.
cord-024061-gxv8y146	253	1	We	-PRON-	PRP
cord-024061-gxv8y146	253	2	excluded	exclude	VBD
cord-024061-gxv8y146	253	3	spatial	spatial	JJ
cord-024061-gxv8y146	253	4	traits	trait	NNS
cord-024061-gxv8y146	253	5	(	(	-LRB-
cord-024061-gxv8y146	253	6	i.e.	i.e.	FW
cord-024061-gxv8y146	253	7	,	,	,
cord-024061-gxv8y146	253	8	U.S.	U.S.	NNP
cord-024061-gxv8y146	253	9	states	state	NNS
cord-024061-gxv8y146	253	10	)	)	-RRB-
cord-024061-gxv8y146	253	11	with	with	IN
cord-024061-gxv8y146	253	12	only	only	RB
cord-024061-gxv8y146	253	13	one	one	CD
cord-024061-gxv8y146	253	14	sequence	sequence	NN
cord-024061-gxv8y146	253	15	(	(	-LRB-
cord-024061-gxv8y146	253	16	Supplementary	Supplementary	NNP
cord-024061-gxv8y146	253	17	Table	Table	NNP
cord-024061-gxv8y146	253	18	2	2	CD
cord-024061-gxv8y146	253	19	)	)	-RRB-
cord-024061-gxv8y146	253	20	leading	lead	VBG
cord-024061-gxv8y146	253	21	to	to	IN
cord-024061-gxv8y146	253	22	the	the	DT
cord-024061-gxv8y146	253	23	inclusion	inclusion	NN
cord-024061-gxv8y146	253	24	of	of	IN
cord-024061-gxv8y146	253	25	10	10	CD
cord-024061-gxv8y146	253	26	states	state	NNS
cord-024061-gxv8y146	253	27	in	in	IN
cord-024061-gxv8y146	253	28	the	the	DT
cord-024061-gxv8y146	253	29	subsequent	subsequent	JJ
cord-024061-gxv8y146	253	30	DTA	DTA	NNP
cord-024061-gxv8y146	253	31	.	.	.
cord-024061-gxv8y146	254	1	Also	also	RB
cord-024061-gxv8y146	254	2	,	,	,
cord-024061-gxv8y146	254	3	we	-PRON-	PRP
cord-024061-gxv8y146	254	4	evaluated	evaluate	VBD
cord-024061-gxv8y146	254	5	the	the	DT
cord-024061-gxv8y146	254	6	fit	fit	NN
cord-024061-gxv8y146	254	7	of	of	IN
cord-024061-gxv8y146	254	8	the	the	DT
cord-024061-gxv8y146	254	9	16	16	CD
cord-024061-gxv8y146	254	10	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	254	11	models	model	NNS
cord-024061-gxv8y146	254	12	to	to	IN
cord-024061-gxv8y146	254	13	the	the	DT
cord-024061-gxv8y146	254	14	HA	HA	NNP
cord-024061-gxv8y146	254	15	and	and	CC
cord-024061-gxv8y146	254	16	PB2	pb2	NN
cord-024061-gxv8y146	254	17	sequences	sequence	NNS
cord-024061-gxv8y146	254	18	using	use	VBG
cord-024061-gxv8y146	254	19	the	the	DT
cord-024061-gxv8y146	254	20	BF	BF	NNP
cord-024061-gxv8y146	254	21	comparisons	comparison	NNS
cord-024061-gxv8y146	254	22	of	of	IN
cord-024061-gxv8y146	254	23	their	-PRON-	PRP$
cord-024061-gxv8y146	254	24	MLL	MLL	NNP
cord-024061-gxv8y146	254	25	estimated	estimate	VBN
cord-024061-gxv8y146	254	26	by	by	IN
cord-024061-gxv8y146	254	27	the	the	DT
cord-024061-gxv8y146	254	28	PS	PS	NNP
cord-024061-gxv8y146	254	29	and	and	CC
cord-024061-gxv8y146	254	30	SS	SS	NNP
cord-024061-gxv8y146	254	31	simulator	simulator	NN
cord-024061-gxv8y146	254	32	in	in	IN
cord-024061-gxv8y146	254	33	order	order	NN
cord-024061-gxv8y146	254	34	to	to	TO
cord-024061-gxv8y146	254	35	select	select	VB
cord-024061-gxv8y146	254	36	the	the	DT
cord-024061-gxv8y146	254	37	most	most	RBS
cord-024061-gxv8y146	254	38	realistic	realistic	JJ
cord-024061-gxv8y146	254	39	model	model	NN
cord-024061-gxv8y146	254	40	and	and	CC
cord-024061-gxv8y146	254	41	correctly	correctly	RB
cord-024061-gxv8y146	254	42	interpret	interpret	VB
cord-024061-gxv8y146	254	43	its	-PRON-	PRP$
cord-024061-gxv8y146	254	44	posterior	posterior	JJ
cord-024061-gxv8y146	254	45	inferences	inference	NNS
cord-024061-gxv8y146	254	46	.	.	.
cord-024061-gxv8y146	255	1	We	-PRON-	PRP
cord-024061-gxv8y146	255	2	then	then	RB
cord-024061-gxv8y146	255	3	used	use	VBD
cord-024061-gxv8y146	255	4	two	two	CD
cord-024061-gxv8y146	255	5	replicate	replicate	VB
cord-024061-gxv8y146	255	6	MCMC	MCMC	NNP
cord-024061-gxv8y146	255	7	simulations	simulation	NNS
cord-024061-gxv8y146	255	8	for	for	IN
cord-024061-gxv8y146	255	9	150	150	CD
cord-024061-gxv8y146	255	10	million	million	CD
cord-024061-gxv8y146	255	11	cycles	cycle	NNS
cord-024061-gxv8y146	255	12	and	and	CC
cord-024061-gxv8y146	255	13	sampled	sample	VBD
cord-024061-gxv8y146	255	14	every	every	DT
cord-024061-gxv8y146	255	15	1,500th	1,500th	CD
cord-024061-gxv8y146	255	16	state	state	NN
cord-024061-gxv8y146	255	17	for	for	IN
cord-024061-gxv8y146	255	18	each	each	DT
cord-024061-gxv8y146	255	19	candidate	candidate	NN
cord-024061-gxv8y146	255	20	model	model	NN
cord-024061-gxv8y146	255	21	.	.	.
cord-024061-gxv8y146	256	1	After	after	IN
cord-024061-gxv8y146	256	2	assessing	assess	VBG
cord-024061-gxv8y146	256	3	for	for	IN
cord-024061-gxv8y146	256	4	proper	proper	JJ
cord-024061-gxv8y146	256	5	model	model	NN
cord-024061-gxv8y146	256	6	convergence	convergence	NN
cord-024061-gxv8y146	256	7	,	,	,
cord-024061-gxv8y146	256	8	we	-PRON-	PRP
cord-024061-gxv8y146	256	9	compared	compare	VBD
cord-024061-gxv8y146	256	10	the	the	DT
cord-024061-gxv8y146	256	11	inferred	infer	VBN
cord-024061-gxv8y146	256	12	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	256	13	demographics	demographic	NNS
cord-024061-gxv8y146	256	14	of	of	IN
cord-024061-gxv8y146	256	15	each	each	DT
cord-024061-gxv8y146	256	16	candidate	candidate	NN
cord-024061-gxv8y146	256	17	model	model	NN
cord-024061-gxv8y146	256	18	by	by	IN
cord-024061-gxv8y146	256	19	summarizing	summarize	VBG
cord-024061-gxv8y146	256	20	their	-PRON-	PRP$
cord-024061-gxv8y146	256	21	inferred	infer	VBN
cord-024061-gxv8y146	256	22	divergence	divergence	NN
cord-024061-gxv8y146	256	23	times	time	NNS
cord-024061-gxv8y146	256	24	,	,	,
cord-024061-gxv8y146	256	25	substitution	substitution	NN
cord-024061-gxv8y146	256	26	rates	rate	NNS
cord-024061-gxv8y146	256	27	,	,	,
cord-024061-gxv8y146	256	28	and	and	CC
cord-024061-gxv8y146	256	29	TMRCAs	tmrca	NNS
cord-024061-gxv8y146	256	30	.	.	.
cord-024061-gxv8y146	257	1	Besides	besides	RB
cord-024061-gxv8y146	257	2	,	,	,
cord-024061-gxv8y146	257	3	we	-PRON-	PRP
cord-024061-gxv8y146	257	4	then	then	RB
cord-024061-gxv8y146	257	5	generated	generate	VBD
cord-024061-gxv8y146	257	6	the	the	DT
cord-024061-gxv8y146	257	7	SG	SG	NNP
cord-024061-gxv8y146	257	8	plots	plot	NNS
cord-024061-gxv8y146	257	9	to	to	TO
cord-024061-gxv8y146	257	10	compare	compare	VB
cord-024061-gxv8y146	257	11	relative	relative	JJ
cord-024061-gxv8y146	257	12	genetic	genetic	JJ
cord-024061-gxv8y146	257	13	diversity	diversity	NN
cord-024061-gxv8y146	257	14	for	for	IN
cord-024061-gxv8y146	257	15	HA	HA	NNP
cord-024061-gxv8y146	257	16	and	and	CC
cord-024061-gxv8y146	257	17	PB2	PB2	NNP
cord-024061-gxv8y146	257	18	gene	gene	NN
cord-024061-gxv8y146	257	19	segments	segment	NNS
cord-024061-gxv8y146	257	20	inferred	infer	VBN
cord-024061-gxv8y146	257	21	from	from	IN
cord-024061-gxv8y146	257	22	the	the	DT
cord-024061-gxv8y146	257	23	two	two	CD
cord-024061-gxv8y146	257	24	different	different	JJ
cord-024061-gxv8y146	257	25	sites	site	NNS
cord-024061-gxv8y146	257	26	and	and	CC
cord-024061-gxv8y146	257	27	discrete	discrete	JJ
cord-024061-gxv8y146	257	28	spatial	spatial	JJ
cord-024061-gxv8y146	257	29	models	model	NNS
cord-024061-gxv8y146	257	30	.	.	.
cord-024061-gxv8y146	258	1	Similarly	similarly	RB
cord-024061-gxv8y146	258	2	,	,	,
cord-024061-gxv8y146	258	3	we	-PRON-	PRP
cord-024061-gxv8y146	258	4	compared	compare	VBD
cord-024061-gxv8y146	258	5	the	the	DT
cord-024061-gxv8y146	258	6	phylogeographic	phylogeographic	JJ
cord-024061-gxv8y146	258	7	inferences	inference	NNS
cord-024061-gxv8y146	258	8	of	of	IN
cord-024061-gxv8y146	258	9	each	each	DT
cord-024061-gxv8y146	258	10	model	model	NN
cord-024061-gxv8y146	258	11	by	by	IN
cord-024061-gxv8y146	258	12	generating	generate	VBG
cord-024061-gxv8y146	258	13	MCC	MCC	NNP
cord-024061-gxv8y146	258	14	trees	tree	NNS
cord-024061-gxv8y146	258	15	,	,	,
cord-024061-gxv8y146	258	16	summarizing	summarize	VBG
cord-024061-gxv8y146	258	17	the	the	DT
cord-024061-gxv8y146	258	18	RSPPs	rspp	NNS
cord-024061-gxv8y146	258	19	of	of	IN
cord-024061-gxv8y146	258	20	the	the	DT
cord-024061-gxv8y146	258	21	states	state	NNS
cord-024061-gxv8y146	258	22	,	,	,
cord-024061-gxv8y146	258	23	and	and	CC
cord-024061-gxv8y146	258	24	plotting	plot	VBG
cord-024061-gxv8y146	258	25	them	-PRON-	PRP
cord-024061-gxv8y146	258	26	at	at	IN
cord-024061-gxv8y146	258	27	the	the	DT
cord-024061-gxv8y146	258	28	internal	internal	JJ
cord-024061-gxv8y146	258	29	nodes	node	NNS
cord-024061-gxv8y146	258	30	of	of	IN
cord-024061-gxv8y146	258	31	their	-PRON-	PRP$
cord-024061-gxv8y146	258	32	corresponding	correspond	VBG
cord-024061-gxv8y146	258	33	trees	tree	NNS
cord-024061-gxv8y146	258	34	.	.	.
cord-024061-gxv8y146	259	1	Finally	finally	RB
cord-024061-gxv8y146	259	2	,	,	,
cord-024061-gxv8y146	259	3	we	-PRON-	PRP
cord-024061-gxv8y146	259	4	selected	select	VBD
cord-024061-gxv8y146	259	5	and	and	CC
cord-024061-gxv8y146	259	6	plotted	plot	VBD
cord-024061-gxv8y146	259	7	the	the	DT
cord-024061-gxv8y146	259	8	statistically	statistically	RB
cord-024061-gxv8y146	259	9	significant	significant	JJ
cord-024061-gxv8y146	259	10	dispersal	dispersal	NN
cord-024061-gxv8y146	259	11	routes	route	NNS
cord-024061-gxv8y146	259	12	between	between	IN
cord-024061-gxv8y146	259	13	states	state	NNS
cord-024061-gxv8y146	259	14	under	under	IN
cord-024061-gxv8y146	259	15	each	each	DT
cord-024061-gxv8y146	259	16	candidate	candidate	NN
cord-024061-gxv8y146	259	17	model	model	NN
cord-024061-gxv8y146	259	18	using	use	VBG
cord-024061-gxv8y146	259	19	a	a	DT
cord-024061-gxv8y146	259	20	cutoff	cutoff	NN
cord-024061-gxv8y146	259	21	BSSVS	BSSVS	NNP
cord-024061-gxv8y146	259	22	-	-	HYPH
cord-024061-gxv8y146	259	23	BF	BF	NNP
cord-024061-gxv8y146	259	24	≥	≥	NNP
cord-024061-gxv8y146	259	25	10	10	CD
cord-024061-gxv8y146	259	26	.	.	.
cord-024061-gxv8y146	260	1	The	the	DT
cord-024061-gxv8y146	260	2	BIC	BIC	NNP
cord-024061-gxv8y146	260	3	values	value	NNS
cord-024061-gxv8y146	260	4	,	,	,
cord-024061-gxv8y146	260	5	described	describe	VBN
cord-024061-gxv8y146	260	6	above	above	RB
cord-024061-gxv8y146	260	7	,	,	,
cord-024061-gxv8y146	260	8	indicated	indicate	VBD
cord-024061-gxv8y146	260	9	that	that	IN
cord-024061-gxv8y146	260	10	the	the	DT
cord-024061-gxv8y146	260	11	HKY	HKY	NNP
cord-024061-gxv8y146	260	12	+	+	CC
cord-024061-gxv8y146	260	13	Ŵ	ŵ	CD
cord-024061-gxv8y146	260	14	is	be	VBZ
cord-024061-gxv8y146	260	15	the	the	DT
cord-024061-gxv8y146	260	16	best	good	JJS
cord-024061-gxv8y146	260	17	fitting	fitting	JJ
cord-024061-gxv8y146	260	18	substitution	substitution	NN
cord-024061-gxv8y146	260	19	model	model	NN
cord-024061-gxv8y146	260	20	for	for	IN
cord-024061-gxv8y146	260	21	the	the	DT
cord-024061-gxv8y146	260	22	HA	HA	NNP
cord-024061-gxv8y146	260	23	gene	gene	NN
cord-024061-gxv8y146	260	24	segment	segment	NN
cord-024061-gxv8y146	260	25	(	(	-LRB-
cord-024061-gxv8y146	260	26	BIC	BIC	NNP
cord-024061-gxv8y146	260	27	=	=	SYM
cord-024061-gxv8y146	260	28	13,399	13,399	CD
cord-024061-gxv8y146	260	29	)	)	-RRB-
cord-024061-gxv8y146	260	30	,	,	,
cord-024061-gxv8y146	260	31	while	while	IN
cord-024061-gxv8y146	260	32	the	the	DT
cord-024061-gxv8y146	260	33	GTR	GTR	NNP
cord-024061-gxv8y146	260	34	+	+	CC
cord-024061-gxv8y146	260	35	Ŵ	Ŵ	NNP
cord-024061-gxv8y146	260	36	is	be	VBZ
cord-024061-gxv8y146	260	37	the	the	DT
cord-024061-gxv8y146	260	38	best	good	JJS
cord-024061-gxv8y146	260	39	fitting	fitting	JJ
cord-024061-gxv8y146	260	40	substitution	substitution	NN
cord-024061-gxv8y146	260	41	model	model	NN
cord-024061-gxv8y146	260	42	for	for	IN
cord-024061-gxv8y146	260	43	the	the	DT
cord-024061-gxv8y146	260	44	PB2	PB2	NNP
cord-024061-gxv8y146	260	45	gene	gene	NN
cord-024061-gxv8y146	260	46	segment	segment	NN
cord-024061-gxv8y146	260	47	(	(	-LRB-
cord-024061-gxv8y146	260	48	BIC	BIC	NNP
cord-024061-gxv8y146	260	49	=	=	SYM
cord-024061-gxv8y146	260	50	20,029	20,029	CD
cord-024061-gxv8y146	260	51	)	)	-RRB-
cord-024061-gxv8y146	260	52	.	.	.
cord-024061-gxv8y146	261	1	In	in	IN
cord-024061-gxv8y146	261	2	addition	addition	NN
cord-024061-gxv8y146	261	3	,	,	,
cord-024061-gxv8y146	261	4	results	result	NNS
cord-024061-gxv8y146	261	5	of	of	IN
cord-024061-gxv8y146	261	6	the	the	DT
cord-024061-gxv8y146	261	7	BF	BF	NNP
cord-024061-gxv8y146	261	8	values	value	NNS
cord-024061-gxv8y146	261	9	(	(	-LRB-
cord-024061-gxv8y146	261	10	≥5	≥5	NNP
cord-024061-gxv8y146	261	11	)	)	-RRB-
cord-024061-gxv8y146	261	12	indicates	indicate	VBZ
cord-024061-gxv8y146	261	13	that	that	IN
cord-024061-gxv8y146	261	14	the	the	DT
cord-024061-gxv8y146	261	15	best	well	RBS
cord-024061-gxv8y146	261	16	fitting	fitting	JJ
cord-024061-gxv8y146	261	17	branch	branch	NN
cord-024061-gxv8y146	261	18	-	-	HYPH
cord-024061-gxv8y146	261	19	rate	rate	NN
cord-024061-gxv8y146	261	20	and	and	CC
cord-024061-gxv8y146	261	21	node	node	NN
cord-024061-gxv8y146	261	22	-	-	HYPH
cord-024061-gxv8y146	261	23	age	age	NN
cord-024061-gxv8y146	261	24	models	model	NNS
cord-024061-gxv8y146	261	25	to	to	IN
cord-024061-gxv8y146	261	26	the	the	DT
cord-024061-gxv8y146	261	27	sequence	sequence	NN
cord-024061-gxv8y146	261	28	data	datum	NNS
cord-024061-gxv8y146	261	29	were	be	VBD
cord-024061-gxv8y146	261	30	the	the	DT
cord-024061-gxv8y146	261	31	SG	SG	NNP
cord-024061-gxv8y146	261	32	+	+	CC
cord-024061-gxv8y146	261	33	UCLN	UCLN	NNP
cord-024061-gxv8y146	261	34	for	for	IN
cord-024061-gxv8y146	261	35	HA	HA	NNP
cord-024061-gxv8y146	261	36	and	and	CC
cord-024061-gxv8y146	261	37	SG	SG	NNP
cord-024061-gxv8y146	261	38	+	+	CC
cord-024061-gxv8y146	261	39	UCED	UCED	NNP
cord-024061-gxv8y146	261	40	for	for	IN
cord-024061-gxv8y146	261	41	PB2	pb2	NN
cord-024061-gxv8y146	261	42	segments	segment	NNS
cord-024061-gxv8y146	261	43	(	(	-LRB-
cord-024061-gxv8y146	261	44	Supplementary	Supplementary	NNP
cord-024061-gxv8y146	261	45	Tables	Tables	NNPS
cord-024061-gxv8y146	261	46	3	3	CD
cord-024061-gxv8y146	261	47	-	-	SYM
cord-024061-gxv8y146	261	48	6	6	CD
cord-024061-gxv8y146	261	49	)	)	-RRB-
cord-024061-gxv8y146	261	50	.	.	.
cord-024061-gxv8y146	262	1	However	however	RB
cord-024061-gxv8y146	262	2	,	,	,
cord-024061-gxv8y146	262	3	there	there	EX
cord-024061-gxv8y146	262	4	were	be	VBD
cord-024061-gxv8y146	262	5	no	no	DT
cord-024061-gxv8y146	262	6	significant	significant	JJ
cord-024061-gxv8y146	262	7	changes	change	NNS
cord-024061-gxv8y146	262	8	in	in	IN
cord-024061-gxv8y146	262	9	the	the	DT
cord-024061-gxv8y146	262	10	posterior	posterior	JJ
cord-024061-gxv8y146	262	11	demographic	demographic	JJ
cord-024061-gxv8y146	262	12	inferences	inference	NNS
cord-024061-gxv8y146	262	13	when	when	WRB
cord-024061-gxv8y146	262	14	choosing	choose	VBG
cord-024061-gxv8y146	262	15	the	the	DT
cord-024061-gxv8y146	262	16	opposite	opposite	JJ
cord-024061-gxv8y146	262	17	substitution	substitution	NN
cord-024061-gxv8y146	262	18	model	model	NN
cord-024061-gxv8y146	262	19	for	for	IN
cord-024061-gxv8y146	262	20	both	both	DT
cord-024061-gxv8y146	262	21	gene	gene	NN
cord-024061-gxv8y146	262	22	segments	segment	NNS
cord-024061-gxv8y146	262	23	.	.	.
cord-024061-gxv8y146	263	1	Similarly	similarly	RB
cord-024061-gxv8y146	263	2	,	,	,
cord-024061-gxv8y146	263	3	our	-PRON-	PRP$
cord-024061-gxv8y146	263	4	results	result	NNS
cord-024061-gxv8y146	263	5	indicate	indicate	VBP
cord-024061-gxv8y146	263	6	that	that	IN
cord-024061-gxv8y146	263	7	the	the	DT
cord-024061-gxv8y146	263	8	choice	choice	NN
cord-024061-gxv8y146	263	9	of	of	IN
cord-024061-gxv8y146	263	10	discrete	discrete	JJ
cord-024061-gxv8y146	263	11	spatial	spatial	JJ
cord-024061-gxv8y146	263	12	and	and	CC
cord-024061-gxv8y146	263	13	node	node	NN
cord-024061-gxv8y146	263	14	-	-	HYPH
cord-024061-gxv8y146	263	15	age	age	NN
cord-024061-gxv8y146	263	16	models	model	NNS
cord-024061-gxv8y146	263	17	does	do	VBZ
cord-024061-gxv8y146	263	18	not	not	RB
cord-024061-gxv8y146	263	19	substantially	substantially	RB
cord-024061-gxv8y146	263	20	change	change	VB
cord-024061-gxv8y146	263	21	the	the	DT
cord-024061-gxv8y146	263	22	estimated	estimate	VBN
cord-024061-gxv8y146	263	23	divergence	divergence	NN
cord-024061-gxv8y146	263	24	times	time	NNS
cord-024061-gxv8y146	263	25	and	and	CC
cord-024061-gxv8y146	263	26	substitution	substitution	NN
cord-024061-gxv8y146	263	27	rates	rate	NNS
cord-024061-gxv8y146	263	28	/	/	SYM
cord-024061-gxv8y146	263	29	site	site	NN
cord-024061-gxv8y146	263	30	/	/	SYM
cord-024061-gxv8y146	263	31	year	year	NN
cord-024061-gxv8y146	263	32	(	(	-LRB-
cord-024061-gxv8y146	263	33	Figure	figure	NN
cord-024061-gxv8y146	263	34	2	2	CD
cord-024061-gxv8y146	263	35	)	)	-RRB-
cord-024061-gxv8y146	263	36	for	for	IN
cord-024061-gxv8y146	263	37	each	each	DT
cord-024061-gxv8y146	263	38	gene	gene	NN
cord-024061-gxv8y146	263	39	segment	segment	NN
cord-024061-gxv8y146	263	40	alone	alone	RB
cord-024061-gxv8y146	263	41	.	.	.
cord-024061-gxv8y146	264	1	Additionally	additionally	RB
cord-024061-gxv8y146	264	2	,	,	,
cord-024061-gxv8y146	264	3	these	these	DT
cord-024061-gxv8y146	264	4	estimates	estimate	NNS
cord-024061-gxv8y146	264	5	were	be	VBD
cord-024061-gxv8y146	264	6	also	also	RB
cord-024061-gxv8y146	264	7	not	not	RB
cord-024061-gxv8y146	264	8	sensitive	sensitive	JJ
cord-024061-gxv8y146	264	9	to	to	IN
cord-024061-gxv8y146	264	10	the	the	DT
cord-024061-gxv8y146	264	11	choice	choice	NN
cord-024061-gxv8y146	264	12	of	of	IN
cord-024061-gxv8y146	264	13	branch	branch	NN
cord-024061-gxv8y146	264	14	-	-	HYPH
cord-024061-gxv8y146	264	15	rate	rate	NN
cord-024061-gxv8y146	264	16	models	model	NNS
cord-024061-gxv8y146	264	17	(	(	-LRB-
cord-024061-gxv8y146	264	18	i.e.	i.e.	FW
cord-024061-gxv8y146	264	19	,	,	,
cord-024061-gxv8y146	264	20	UCED	UCED	NNP
cord-024061-gxv8y146	264	21	and	and	CC
cord-024061-gxv8y146	264	22	UCLN	UCLN	NNP
cord-024061-gxv8y146	264	23	)	)	-RRB-
cord-024061-gxv8y146	264	24	.	.	.
cord-024061-gxv8y146	265	1	However	however	RB
cord-024061-gxv8y146	265	2	,	,	,
cord-024061-gxv8y146	265	3	when	when	WRB
cord-024061-gxv8y146	265	4	comparing	compare	VBG
cord-024061-gxv8y146	265	5	divergence	divergence	NN
cord-024061-gxv8y146	265	6	times	time	NNS
cord-024061-gxv8y146	265	7	between	between	IN
cord-024061-gxv8y146	265	8	segments	segment	NNS
cord-024061-gxv8y146	265	9	,	,	,
cord-024061-gxv8y146	265	10	our	-PRON-	PRP$
cord-024061-gxv8y146	265	11	results	result	NNS
cord-024061-gxv8y146	265	12	indicate	indicate	VBP
cord-024061-gxv8y146	265	13	substantial	substantial	JJ
cord-024061-gxv8y146	265	14	differences	difference	NNS
cord-024061-gxv8y146	265	15	in	in	IN
cord-024061-gxv8y146	265	16	a	a	DT
cord-024061-gxv8y146	265	17	magnitude	magnitude	NN
cord-024061-gxv8y146	265	18	of	of	IN
cord-024061-gxv8y146	265	19	∼8	∼8	CD
cord-024061-gxv8y146	265	20	years	year	NNS
cord-024061-gxv8y146	265	21	,	,	,
cord-024061-gxv8y146	265	22	in	in	IN
cord-024061-gxv8y146	265	23	which	which	WDT
cord-024061-gxv8y146	265	24	the	the	DT
cord-024061-gxv8y146	265	25	divergence	divergence	NN
cord-024061-gxv8y146	265	26	time	time	NN
cord-024061-gxv8y146	265	27	for	for	IN
cord-024061-gxv8y146	265	28	the	the	DT
cord-024061-gxv8y146	265	29	HA	HA	NNP
cord-024061-gxv8y146	265	30	segment	segment	NN
cord-024061-gxv8y146	265	31	was	be	VBD
cord-024061-gxv8y146	265	32	around	around	RB
cord-024061-gxv8y146	265	33	2013	2013	CD
cord-024061-gxv8y146	265	34	(	(	-LRB-
cord-024061-gxv8y146	265	35	Figure	figure	NN
cord-024061-gxv8y146	265	36	2A	2a	CD
cord-024061-gxv8y146	265	37	)	)	-RRB-
cord-024061-gxv8y146	265	38	,	,	,
cord-024061-gxv8y146	265	39	while	while	IN
cord-024061-gxv8y146	265	40	for	for	IN
cord-024061-gxv8y146	265	41	the	the	DT
cord-024061-gxv8y146	265	42	PB2	PB2	NNP
cord-024061-gxv8y146	265	43	segment	segment	NN
cord-024061-gxv8y146	265	44	,	,	,
cord-024061-gxv8y146	265	45	it	-PRON-	PRP
cord-024061-gxv8y146	265	46	was	be	VBD
cord-024061-gxv8y146	265	47	around	around	RB
cord-024061-gxv8y146	265	48	2005	2005	CD
cord-024061-gxv8y146	266	1	(	(	-LRB-
cord-024061-gxv8y146	266	2	Figure	figure	NN
cord-024061-gxv8y146	266	3	2C	2c	NN
cord-024061-gxv8y146	266	4	)	)	-RRB-
cord-024061-gxv8y146	266	5	.	.	.
cord-024061-gxv8y146	267	1	No	no	DT
cord-024061-gxv8y146	267	2	differences	difference	NNS
cord-024061-gxv8y146	267	3	were	be	VBD
cord-024061-gxv8y146	267	4	observed	observe	VBN
cord-024061-gxv8y146	267	5	in	in	IN
cord-024061-gxv8y146	267	6	the	the	DT
cord-024061-gxv8y146	267	7	substitution	substitution	NN
cord-024061-gxv8y146	267	8	rates	rate	NNS
cord-024061-gxv8y146	267	9	/	/	SYM
cord-024061-gxv8y146	267	10	site	site	NN
cord-024061-gxv8y146	267	11	/	/	SYM
cord-024061-gxv8y146	267	12	year	year	NN
cord-024061-gxv8y146	267	13	between	between	IN
cord-024061-gxv8y146	267	14	the	the	DT
cord-024061-gxv8y146	267	15	two	two	CD
cord-024061-gxv8y146	267	16	gene	gene	NN
cord-024061-gxv8y146	267	17	segments	segment	NNS
cord-024061-gxv8y146	267	18	,	,	,
cord-024061-gxv8y146	267	19	which	which	WDT
cord-024061-gxv8y146	267	20	were	be	VBD
cord-024061-gxv8y146	267	21	ranging	range	VBG
cord-024061-gxv8y146	267	22	between	between	IN
cord-024061-gxv8y146	267	23	3.3	3.3	CD
cord-024061-gxv8y146	267	24	×	×	NN
cord-024061-gxv8y146	267	25	10	10	CD
cord-024061-gxv8y146	267	26	−3	−3	NN
cord-024061-gxv8y146	267	27	(	(	-LRB-
cord-024061-gxv8y146	267	28	95	95	CD
cord-024061-gxv8y146	267	29	%	%	NN
cord-024061-gxv8y146	267	30	HPD	HPD	NNP
cord-024061-gxv8y146	267	31	;	;	:
cord-024061-gxv8y146	267	32	from	from	IN
cord-024061-gxv8y146	267	33	2.8	2.8	CD
cord-024061-gxv8y146	267	34	×	×	NN
cord-024061-gxv8y146	267	35	10	10	CD
cord-024061-gxv8y146	267	36	−3	−3	NN
cord-024061-gxv8y146	267	37	to	to	IN
cord-024061-gxv8y146	267	38	3.9	3.9	CD
cord-024061-gxv8y146	267	39	×	×	NN
cord-024061-gxv8y146	267	40	10	10	CD
cord-024061-gxv8y146	267	41	−3	−3	NNP
cord-024061-gxv8y146	267	42	)	)	-RRB-
cord-024061-gxv8y146	267	43	and	and	CC
cord-024061-gxv8y146	267	44	2.9	2.9	CD
cord-024061-gxv8y146	267	45	×	×	NN
cord-024061-gxv8y146	267	46	10	10	CD
cord-024061-gxv8y146	267	47	−3	−3	NN
cord-024061-gxv8y146	267	48	(	(	-LRB-
cord-024061-gxv8y146	267	49	95	95	CD
cord-024061-gxv8y146	267	50	%	%	NN
cord-024061-gxv8y146	267	51	HPD	HPD	NNP
cord-024061-gxv8y146	267	52	;	;	:
cord-024061-gxv8y146	267	53	from	from	IN
cord-024061-gxv8y146	267	54	2.2	2.2	CD
cord-024061-gxv8y146	267	55	×	×	CD
cord-024061-gxv8y146	267	56	10	10	CD
cord-024061-gxv8y146	267	57	−3	−3	NN
cord-024061-gxv8y146	267	58	to	to	IN
cord-024061-gxv8y146	267	59	3.8	3.8	CD
cord-024061-gxv8y146	267	60	×	×	NN
cord-024061-gxv8y146	267	61	10	10	CD
cord-024061-gxv8y146	267	62	−3	−3	NN
cord-024061-gxv8y146	267	63	)	)	-RRB-
cord-024061-gxv8y146	267	64	for	for	IN
cord-024061-gxv8y146	267	65	HA	HA	NNP
cord-024061-gxv8y146	267	66	and	and	CC
cord-024061-gxv8y146	267	67	PB2	PB2	NNP
cord-024061-gxv8y146	267	68	segments	segment	NNS
cord-024061-gxv8y146	267	69	,	,	,
cord-024061-gxv8y146	267	70	respectively	respectively	RB
cord-024061-gxv8y146	267	71	(	(	-LRB-
cord-024061-gxv8y146	267	72	Figures	figure	NNS
cord-024061-gxv8y146	267	73	2B	2b	CD
cord-024061-gxv8y146	267	74	,	,	,
cord-024061-gxv8y146	267	75	D	D	NNP
cord-024061-gxv8y146	267	76	)	)	-RRB-
cord-024061-gxv8y146	267	77	.	.	.
cord-024061-gxv8y146	268	1	Similarly	similarly	RB
cord-024061-gxv8y146	268	2	,	,	,
cord-024061-gxv8y146	268	3	posterior	posterior	JJ
cord-024061-gxv8y146	268	4	estimates	estimate	NNS
cord-024061-gxv8y146	268	5	of	of	IN
cord-024061-gxv8y146	268	6	TMRCAs	tmrca	NNS
cord-024061-gxv8y146	268	7	were	be	VBD
cord-024061-gxv8y146	268	8	not	not	RB
cord-024061-gxv8y146	268	9	sensitive	sensitive	JJ
cord-024061-gxv8y146	268	10	to	to	IN
cord-024061-gxv8y146	268	11	the	the	DT
cord-024061-gxv8y146	268	12	choice	choice	NN
cord-024061-gxv8y146	268	13	of	of	IN
cord-024061-gxv8y146	268	14	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	268	15	priors	prior	NNS
cord-024061-gxv8y146	268	16	but	but	CC
cord-024061-gxv8y146	268	17	were	be	VBD
cord-024061-gxv8y146	268	18	different	different	JJ
cord-024061-gxv8y146	268	19	between	between	IN
cord-024061-gxv8y146	268	20	the	the	DT
cord-024061-gxv8y146	268	21	two	two	CD
cord-024061-gxv8y146	268	22	gene	gene	NN
cord-024061-gxv8y146	268	23	segments	segment	NNS
cord-024061-gxv8y146	268	24	(	(	-LRB-
cord-024061-gxv8y146	268	25	Figure	figure	NN
cord-024061-gxv8y146	268	26	3	3	CD
cord-024061-gxv8y146	268	27	)	)	-RRB-
cord-024061-gxv8y146	268	28	.	.	.
cord-024061-gxv8y146	269	1	Hence	hence	RB
cord-024061-gxv8y146	269	2	,	,	,
cord-024061-gxv8y146	269	3	based	base	VBN
cord-024061-gxv8y146	269	4	on	on	IN
cord-024061-gxv8y146	269	5	the	the	DT
cord-024061-gxv8y146	269	6	HA	HA	NNP
cord-024061-gxv8y146	269	7	segment	segment	NN
cord-024061-gxv8y146	269	8	,	,	,
cord-024061-gxv8y146	269	9	our	-PRON-	PRP$
cord-024061-gxv8y146	269	10	results	result	NNS
cord-024061-gxv8y146	269	11	hint	hint	VBP
cord-024061-gxv8y146	269	12	that	that	IN
cord-024061-gxv8y146	269	13	the	the	DT
cord-024061-gxv8y146	269	14	oldest	old	JJS
cord-024061-gxv8y146	269	15	humanlike	humanlike	JJ
cord-024061-gxv8y146	269	16	H3	H3	NNP
cord-024061-gxv8y146	269	17	strains	strain	NNS
cord-024061-gxv8y146	269	18	emerged	emerge	VBD
cord-024061-gxv8y146	269	19	from	from	IN
cord-024061-gxv8y146	269	20	the	the	DT
cord-024061-gxv8y146	269	21	state	state	NN
cord-024061-gxv8y146	269	22	of	of	IN
cord-024061-gxv8y146	269	23	Minnesota	Minnesota	NNP
cord-024061-gxv8y146	269	24	in	in	IN
cord-024061-gxv8y146	269	25	mid-2013	mid-2013	NN
cord-024061-gxv8y146	269	26	(	(	-LRB-
cord-024061-gxv8y146	269	27	Figures	figure	NNS
cord-024061-gxv8y146	269	28	3A	3a	NN
cord-024061-gxv8y146	269	29	,	,	,
cord-024061-gxv8y146	269	30	B	B	NNP
cord-024061-gxv8y146	269	31	)	)	-RRB-
cord-024061-gxv8y146	269	32	,	,	,
cord-024061-gxv8y146	269	33	but	but	CC
cord-024061-gxv8y146	269	34	with	with	IN
cord-024061-gxv8y146	269	35	a	a	DT
cord-024061-gxv8y146	269	36	notable	notable	JJ
cord-024061-gxv8y146	269	37	overlap	overlap	NN
cord-024061-gxv8y146	269	38	in	in	IN
cord-024061-gxv8y146	269	39	the	the	DT
cord-024061-gxv8y146	269	40	95	95	CD
cord-024061-gxv8y146	269	41	%	%	NN
cord-024061-gxv8y146	269	42	HPD	HPD	NNP
cord-024061-gxv8y146	269	43	of	of	IN
cord-024061-gxv8y146	269	44	the	the	DT
cord-024061-gxv8y146	269	45	TMRCAs	tmrca	NNS
cord-024061-gxv8y146	269	46	inferred	infer	VBN
cord-024061-gxv8y146	269	47	for	for	IN
cord-024061-gxv8y146	269	48	other	other	JJ
cord-024061-gxv8y146	269	49	states	state	NNS
cord-024061-gxv8y146	269	50	(	(	-LRB-
cord-024061-gxv8y146	269	51	excluding	exclude	VBG
cord-024061-gxv8y146	269	52	Maryland	Maryland	NNP
cord-024061-gxv8y146	269	53	)	)	-RRB-
cord-024061-gxv8y146	269	54	.	.	.
cord-024061-gxv8y146	270	1	However	however	RB
cord-024061-gxv8y146	270	2	,	,	,
cord-024061-gxv8y146	270	3	results	result	NNS
cord-024061-gxv8y146	270	4	distinctly	distinctly	RB
cord-024061-gxv8y146	270	5	suggest	suggest	VBP
cord-024061-gxv8y146	270	6	that	that	IN
cord-024061-gxv8y146	270	7	the	the	DT
cord-024061-gxv8y146	270	8	youngest	young	JJS
cord-024061-gxv8y146	270	9	strains	strain	NNS
cord-024061-gxv8y146	270	10	emerged	emerge	VBD
cord-024061-gxv8y146	270	11	from	from	IN
cord-024061-gxv8y146	270	12	the	the	DT
cord-024061-gxv8y146	270	13	state	state	NN
cord-024061-gxv8y146	270	14	of	of	IN
cord-024061-gxv8y146	270	15	Maryland	Maryland	NNP
cord-024061-gxv8y146	270	16	in	in	IN
cord-024061-gxv8y146	270	17	early	early	JJ
cord-024061-gxv8y146	270	18	2017	2017	CD
cord-024061-gxv8y146	270	19	.	.	.
cord-024061-gxv8y146	271	1	Results	result	NNS
cord-024061-gxv8y146	271	2	of	of	IN
cord-024061-gxv8y146	271	3	the	the	DT
cord-024061-gxv8y146	271	4	PB2	PB2	NNP
cord-024061-gxv8y146	271	5	segment	segment	NN
cord-024061-gxv8y146	271	6	were	be	VBD
cord-024061-gxv8y146	271	7	inconclusive	inconclusive	JJ
cord-024061-gxv8y146	271	8	in	in	IN
cord-024061-gxv8y146	271	9	terms	term	NNS
cord-024061-gxv8y146	271	10	of	of	IN
cord-024061-gxv8y146	271	11	determining	determine	VBG
cord-024061-gxv8y146	271	12	the	the	DT
cord-024061-gxv8y146	271	13	oldest	old	JJS
cord-024061-gxv8y146	271	14	strains	strain	NNS
cord-024061-gxv8y146	271	15	,	,	,
cord-024061-gxv8y146	271	16	but	but	CC
cord-024061-gxv8y146	271	17	identical	identical	JJ
cord-024061-gxv8y146	271	18	to	to	IN
cord-024061-gxv8y146	271	19	the	the	DT
cord-024061-gxv8y146	271	20	HA	HA	NNP
cord-024061-gxv8y146	271	21	gene	gene	NN
cord-024061-gxv8y146	271	22	in	in	IN
cord-024061-gxv8y146	271	23	identifying	identify	VBG
cord-024061-gxv8y146	271	24	Maryland	Maryland	NNP
cord-024061-gxv8y146	271	25	as	as	IN
cord-024061-gxv8y146	271	26	the	the	DT
cord-024061-gxv8y146	271	27	state	state	NN
cord-024061-gxv8y146	271	28	of	of	IN
cord-024061-gxv8y146	271	29	the	the	DT
cord-024061-gxv8y146	271	30	youngest	young	JJS
cord-024061-gxv8y146	271	31	viral	viral	JJ
cord-024061-gxv8y146	271	32	strains	strain	NNS
cord-024061-gxv8y146	271	33	(	(	-LRB-
cord-024061-gxv8y146	271	34	Figures	figure	NNS
cord-024061-gxv8y146	271	35	3C	3c	NN
cord-024061-gxv8y146	271	36	,	,	,
cord-024061-gxv8y146	271	37	D	D	NNP
cord-024061-gxv8y146	271	38	)	)	-RRB-
cord-024061-gxv8y146	271	39	.	.	.
cord-024061-gxv8y146	272	1	Also	also	RB
cord-024061-gxv8y146	272	2	,	,	,
cord-024061-gxv8y146	272	3	the	the	DT
cord-024061-gxv8y146	272	4	choice	choice	NN
cord-024061-gxv8y146	272	5	of	of	IN
cord-024061-gxv8y146	272	6	spatial	spatial	JJ
cord-024061-gxv8y146	272	7	trait	trait	NN
cord-024061-gxv8y146	272	8	model	model	NN
cord-024061-gxv8y146	272	9	did	do	VBD
cord-024061-gxv8y146	272	10	not	not	RB
cord-024061-gxv8y146	272	11	affect	affect	VB
cord-024061-gxv8y146	272	12	our	-PRON-	PRP$
cord-024061-gxv8y146	272	13	estimates	estimate	NNS
cord-024061-gxv8y146	272	14	of	of	IN
cord-024061-gxv8y146	272	15	genetic	genetic	JJ
cord-024061-gxv8y146	272	16	diversity	diversity	NN
cord-024061-gxv8y146	272	17	for	for	IN
cord-024061-gxv8y146	272	18	both	both	DT
cord-024061-gxv8y146	272	19	HA	HA	NNP
cord-024061-gxv8y146	272	20	and	and	CC
cord-024061-gxv8y146	272	21	PB2	pb2	NN
cord-024061-gxv8y146	272	22	segments	segment	NNS
cord-024061-gxv8y146	272	23	(	(	-LRB-
cord-024061-gxv8y146	272	24	Figure	figure	NN
cord-024061-gxv8y146	272	25	4	4	CD
cord-024061-gxv8y146	272	26	)	)	-RRB-
cord-024061-gxv8y146	272	27	.	.	.
cord-024061-gxv8y146	273	1	Our	-PRON-	PRP$
cord-024061-gxv8y146	273	2	SG	SG	NNP
cord-024061-gxv8y146	273	3	plots	plot	NNS
cord-024061-gxv8y146	273	4	inferred	infer	VBD
cord-024061-gxv8y146	273	5	seasonal	seasonal	JJ
cord-024061-gxv8y146	273	6	variations	variation	NNS
cord-024061-gxv8y146	273	7	in	in	IN
cord-024061-gxv8y146	273	8	terms	term	NNS
cord-024061-gxv8y146	273	9	of	of	IN
cord-024061-gxv8y146	273	10	increases	increase	NNS
cord-024061-gxv8y146	273	11	and	and	CC
cord-024061-gxv8y146	273	12	decreases	decrease	NNS
cord-024061-gxv8y146	273	13	,	,	,
cord-024061-gxv8y146	273	14	in	in	IN
cord-024061-gxv8y146	273	15	the	the	DT
cord-024061-gxv8y146	273	16	genetic	genetic	JJ
cord-024061-gxv8y146	273	17	diversity	diversity	NN
cord-024061-gxv8y146	273	18	through	through	IN
cord-024061-gxv8y146	273	19	time	time	NN
cord-024061-gxv8y146	273	20	for	for	IN
cord-024061-gxv8y146	273	21	HA	HA	NNP
cord-024061-gxv8y146	273	22	segments	segment	NNS
cord-024061-gxv8y146	273	23	(	(	-LRB-
cord-024061-gxv8y146	273	24	Figures	figure	NNS
cord-024061-gxv8y146	273	25	4A	4a	CD
cord-024061-gxv8y146	273	26	,	,	,
cord-024061-gxv8y146	273	27	B	B	NNP
cord-024061-gxv8y146	273	28	)	)	-RRB-
cord-024061-gxv8y146	273	29	,	,	,
cord-024061-gxv8y146	273	30	while	while	IN
cord-024061-gxv8y146	273	31	the	the	DT
cord-024061-gxv8y146	273	32	genetic	genetic	JJ
cord-024061-gxv8y146	273	33	diversity	diversity	NN
cord-024061-gxv8y146	273	34	of	of	IN
cord-024061-gxv8y146	273	35	the	the	DT
cord-024061-gxv8y146	273	36	PB2	PB2	NNP
cord-024061-gxv8y146	273	37	segment	segment	NN
cord-024061-gxv8y146	273	38	gene	gene	NN
cord-024061-gxv8y146	273	39	slightly	slightly	RB
cord-024061-gxv8y146	273	40	declined	decline	VBD
cord-024061-gxv8y146	273	41	after	after	IN
cord-024061-gxv8y146	273	42	2015	2015	CD
cord-024061-gxv8y146	273	43	(	(	-LRB-
cord-024061-gxv8y146	273	44	Figures	figure	NNS
cord-024061-gxv8y146	273	45	4C	4c	CD
cord-024061-gxv8y146	273	46	,	,	,
cord-024061-gxv8y146	273	47	D	D	NNP
cord-024061-gxv8y146	273	48	)	)	-RRB-
cord-024061-gxv8y146	273	49	.	.	.
cord-024061-gxv8y146	274	1	Our	-PRON-	PRP$
cord-024061-gxv8y146	274	2	inferred	infer	VBN
cord-024061-gxv8y146	274	3	phylogeographic	phylogeographic	JJ
cord-024061-gxv8y146	274	4	posteriors	posterior	NNS
cord-024061-gxv8y146	274	5	did	do	VBD
cord-024061-gxv8y146	274	6	not	not	RB
cord-024061-gxv8y146	274	7	show	show	VB
cord-024061-gxv8y146	274	8	sensitivity	sensitivity	NN
cord-024061-gxv8y146	274	9	to	to	IN
cord-024061-gxv8y146	274	10	the	the	DT
cord-024061-gxv8y146	274	11	selection	selection	NN
cord-024061-gxv8y146	274	12	of	of	IN
cord-024061-gxv8y146	274	13	substitution	substitution	NN
cord-024061-gxv8y146	274	14	or	or	CC
cord-024061-gxv8y146	274	15	molecular	molecular	JJ
cord-024061-gxv8y146	274	16	clock	clock	NN
cord-024061-gxv8y146	274	17	priors	prior	NNS
cord-024061-gxv8y146	274	18	.	.	.
cord-024061-gxv8y146	275	1	However	however	RB
cord-024061-gxv8y146	275	2	,	,	,
cord-024061-gxv8y146	275	3	substantial	substantial	JJ
cord-024061-gxv8y146	275	4	differences	difference	NNS
cord-024061-gxv8y146	275	5	were	be	VBD
cord-024061-gxv8y146	275	6	inferred	infer	VBN
cord-024061-gxv8y146	275	7	when	when	WRB
cord-024061-gxv8y146	275	8	selecting	select	VBG
cord-024061-gxv8y146	275	9	different	different	JJ
cord-024061-gxv8y146	275	10	node	node	NN
cord-024061-gxv8y146	275	11	-	-	HYPH
cord-024061-gxv8y146	275	12	age	age	NN
cord-024061-gxv8y146	275	13	and	and	CC
cord-024061-gxv8y146	275	14	discrete	discrete	JJ
cord-024061-gxv8y146	275	15	spatial	spatial	JJ
cord-024061-gxv8y146	275	16	trait	trait	NN
cord-024061-gxv8y146	275	17	priors	prior	NNS
cord-024061-gxv8y146	275	18	.	.	.
cord-024061-gxv8y146	276	1	Inferences	inference	NNS
cord-024061-gxv8y146	276	2	from	from	IN
cord-024061-gxv8y146	276	3	both	both	CC
cord-024061-gxv8y146	276	4	the	the	DT
cord-024061-gxv8y146	276	5	CP	cp	NN
cord-024061-gxv8y146	276	6	and	and	CC
cord-024061-gxv8y146	276	7	the	the	DT
cord-024061-gxv8y146	276	8	EX	ex	NN
cord-024061-gxv8y146	276	9	node	node	NN
cord-024061-gxv8y146	276	10	age	age	NN
cord-024061-gxv8y146	276	11	with	with	IN
cord-024061-gxv8y146	276	12	the	the	DT
cord-024061-gxv8y146	276	13	asymmetric	asymmetric	JJ
cord-024061-gxv8y146	276	14	models	model	NNS
cord-024061-gxv8y146	276	15	implicated	implicate	VBD
cord-024061-gxv8y146	276	16	Missouri	Missouri	NNP
cord-024061-gxv8y146	276	17	as	as	IN
cord-024061-gxv8y146	276	18	the	the	DT
cord-024061-gxv8y146	276	19	most	most	RBS
cord-024061-gxv8y146	276	20	likely	likely	JJ
cord-024061-gxv8y146	276	21	ancestral	ancestral	JJ
cord-024061-gxv8y146	276	22	state	state	NN
cord-024061-gxv8y146	276	23	for	for	IN
cord-024061-gxv8y146	276	24	the	the	DT
cord-024061-gxv8y146	276	25	human	human	NN
cord-024061-gxv8y146	276	26	-	-	HYPH
cord-024061-gxv8y146	276	27	like	like	JJ
cord-024061-gxv8y146	276	28	H3	H3	NNP
cord-024061-gxv8y146	276	29	virus	virus	NN
cord-024061-gxv8y146	276	30	currently	currently	RB
cord-024061-gxv8y146	276	31	circulating	circulate	VBG
cord-024061-gxv8y146	276	32	in	in	IN
cord-024061-gxv8y146	276	33	the	the	DT
cord-024061-gxv8y146	276	34	United	United	NNP
cord-024061-gxv8y146	276	35	States	States	NNP
cord-024061-gxv8y146	276	36	when	when	WRB
cord-024061-gxv8y146	276	37	using	use	VBG
cord-024061-gxv8y146	276	38	the	the	DT
cord-024061-gxv8y146	276	39	HA	HA	NNP
cord-024061-gxv8y146	276	40	gene	gene	NN
cord-024061-gxv8y146	276	41	segment	segment	NN
cord-024061-gxv8y146	276	42	(	(	-LRB-
cord-024061-gxv8y146	276	43	Figures	figure	NNS
cord-024061-gxv8y146	276	44	5A	5a	NN
cord-024061-gxv8y146	276	45	,	,	,
cord-024061-gxv8y146	276	46	B	b	NN
cord-024061-gxv8y146	276	47	)	)	-RRB-
cord-024061-gxv8y146	276	48	.	.	.
cord-024061-gxv8y146	277	1	However	however	RB
cord-024061-gxv8y146	277	2	,	,	,
cord-024061-gxv8y146	277	3	the	the	DT
cord-024061-gxv8y146	277	4	EGx	EGx	NNS
cord-024061-gxv8y146	277	5	and	and	CC
cord-024061-gxv8y146	277	6	the	the	DT
cord-024061-gxv8y146	277	7	SG	SG	NNP
cord-024061-gxv8y146	277	8	with	with	IN
cord-024061-gxv8y146	277	9	the	the	DT
cord-024061-gxv8y146	277	10	asymmetric	asymmetric	JJ
cord-024061-gxv8y146	277	11	models	model	NNS
cord-024061-gxv8y146	277	12	Illinois	Illinois	NNP
cord-024061-gxv8y146	277	13	and	and	CC
cord-024061-gxv8y146	277	14	Minnesota	Minnesota	NNP
cord-024061-gxv8y146	277	15	as	as	IN
cord-024061-gxv8y146	277	16	the	the	DT
cord-024061-gxv8y146	277	17	most	most	RBS
cord-024061-gxv8y146	277	18	likely	likely	JJ
cord-024061-gxv8y146	277	19	ancestral	ancestral	JJ
cord-024061-gxv8y146	277	20	states	state	NNS
cord-024061-gxv8y146	277	21	,	,	,
cord-024061-gxv8y146	277	22	respectively	respectively	RB
cord-024061-gxv8y146	277	23	(	(	-LRB-
cord-024061-gxv8y146	277	24	Figures	figure	NNS
cord-024061-gxv8y146	277	25	5C	5c	CD
cord-024061-gxv8y146	277	26	,	,	,
cord-024061-gxv8y146	277	27	D	D	NNP
cord-024061-gxv8y146	277	28	)	)	-RRB-
cord-024061-gxv8y146	277	29	.	.	.
cord-024061-gxv8y146	278	1	Yet	yet	RB
cord-024061-gxv8y146	278	2	,	,	,
cord-024061-gxv8y146	278	3	when	when	WRB
cord-024061-gxv8y146	278	4	using	use	VBG
cord-024061-gxv8y146	278	5	the	the	DT
cord-024061-gxv8y146	278	6	HA	HA	NNP
cord-024061-gxv8y146	278	7	segment	segment	NN
cord-024061-gxv8y146	278	8	,	,	,
cord-024061-gxv8y146	278	9	the	the	DT
cord-024061-gxv8y146	278	10	symmetric	symmetric	JJ
cord-024061-gxv8y146	278	11	model	model	NN
cord-024061-gxv8y146	278	12	with	with	IN
cord-024061-gxv8y146	278	13	the	the	DT
cord-024061-gxv8y146	278	14	CP	cp	NN
cord-024061-gxv8y146	278	15	,	,	,
cord-024061-gxv8y146	278	16	EG	EG	NNP
cord-024061-gxv8y146	278	17	,	,	,
cord-024061-gxv8y146	278	18	and	and	CC
cord-024061-gxv8y146	278	19	EGx	egx	NN
cord-024061-gxv8y146	278	20	priors	prior	NNS
cord-024061-gxv8y146	278	21	consistently	consistently	RB
cord-024061-gxv8y146	278	22	implicated	implicate	VBD
cord-024061-gxv8y146	278	23	Minnesota	Minnesota	NNP
cord-024061-gxv8y146	278	24	with	with	IN
cord-024061-gxv8y146	278	25	approximately	approximately	RB
cord-024061-gxv8y146	278	26	similar	similar	JJ
cord-024061-gxv8y146	278	27	estimates	estimate	NNS
cord-024061-gxv8y146	278	28	of	of	IN
cord-024061-gxv8y146	278	29	RSPPs	rspp	NNS
cord-024061-gxv8y146	279	1	(	(	-LRB-
cord-024061-gxv8y146	279	2	Figures	figure	NNS
cord-024061-gxv8y146	279	3	5E	5e	NN
cord-024061-gxv8y146	279	4	-	-	HYPH
cord-024061-gxv8y146	279	5	G	G	NNP
cord-024061-gxv8y146	279	6	)	)	-RRB-
cord-024061-gxv8y146	279	7	.	.	.
cord-024061-gxv8y146	280	1	In	in	IN
cord-024061-gxv8y146	280	2	contrast	contrast	NN
cord-024061-gxv8y146	280	3	,	,	,
cord-024061-gxv8y146	280	4	the	the	DT
cord-024061-gxv8y146	280	5	use	use	NN
cord-024061-gxv8y146	280	6	of	of	IN
cord-024061-gxv8y146	280	7	the	the	DT
cord-024061-gxv8y146	280	8	symmetric	symmetric	JJ
cord-024061-gxv8y146	280	9	model	model	NN
cord-024061-gxv8y146	280	10	with	with	IN
cord-024061-gxv8y146	280	11	the	the	DT
cord-024061-gxv8y146	280	12	SG	SG	NNP
cord-024061-gxv8y146	280	13	prior	prior	RB
cord-024061-gxv8y146	280	14	implicated	implicate	VBN
cord-024061-gxv8y146	280	15	Iowa	Iowa	NNP
cord-024061-gxv8y146	280	16	as	as	IN
cord-024061-gxv8y146	280	17	the	the	DT
cord-024061-gxv8y146	280	18	ancestral	ancestral	JJ
cord-024061-gxv8y146	280	19	location	location	NN
cord-024061-gxv8y146	280	20	for	for	IN
cord-024061-gxv8y146	280	21	the	the	DT
cord-024061-gxv8y146	280	22	currently	currently	RB
cord-024061-gxv8y146	280	23	circulating	circulate	VBG
cord-024061-gxv8y146	280	24	human	human	JJ
cord-024061-gxv8y146	280	25	-	-	HYPH
cord-024061-gxv8y146	280	26	like	like	JJ
cord-024061-gxv8y146	280	27	H3	H3	NNP
cord-024061-gxv8y146	280	28	strains	strain	NNS
cord-024061-gxv8y146	280	29	(	(	-LRB-
cord-024061-gxv8y146	280	30	RSPP	RSPP	NNP
cord-024061-gxv8y146	280	31	=	=	SYM
cord-024061-gxv8y146	280	32	0.36	0.36	CD
cord-024061-gxv8y146	280	33	)	)	-RRB-
cord-024061-gxv8y146	280	34	(	(	-LRB-
cord-024061-gxv8y146	280	35	Figure	figure	NN
cord-024061-gxv8y146	280	36	5H	5h	NN
cord-024061-gxv8y146	280	37	)	)	-RRB-
cord-024061-gxv8y146	280	38	.	.	.
cord-024061-gxv8y146	281	1	Interestingly	interestingly	RB
cord-024061-gxv8y146	281	2	,	,	,
cord-024061-gxv8y146	281	3	the	the	DT
cord-024061-gxv8y146	281	4	HA	HA	NNP
cord-024061-gxv8y146	281	5	sequence	sequence	NN
cord-024061-gxv8y146	281	6	data	datum	NNS
cord-024061-gxv8y146	281	7	uniquely	uniquely	RB
cord-024061-gxv8y146	281	8	favored	favor	VBD
cord-024061-gxv8y146	281	9	this	this	DT
cord-024061-gxv8y146	281	10	prior	prior	JJ
cord-024061-gxv8y146	281	11	combination	combination	NN
cord-024061-gxv8y146	281	12	when	when	WRB
cord-024061-gxv8y146	281	13	using	use	VBG
cord-024061-gxv8y146	281	14	the	the	DT
cord-024061-gxv8y146	281	15	BF	BF	NNP
cord-024061-gxv8y146	281	16	comparisons	comparison	NNS
cord-024061-gxv8y146	281	17	for	for	IN
cord-024061-gxv8y146	281	18	the	the	DT
cord-024061-gxv8y146	281	19	best	good	JJS
cord-024061-gxv8y146	281	20	fitting	fitting	JJ
cord-024061-gxv8y146	281	21	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	281	22	model	model	NN
cord-024061-gxv8y146	281	23	(	(	-LRB-
cord-024061-gxv8y146	281	24	Supplementary	Supplementary	NNP
cord-024061-gxv8y146	281	25	Tables	Tables	NNPS
cord-024061-gxv8y146	281	26	3	3	CD
cord-024061-gxv8y146	281	27	,	,	,
cord-024061-gxv8y146	281	28	4	4	CD
cord-024061-gxv8y146	281	29	)	)	-RRB-
cord-024061-gxv8y146	281	30	.	.	.
cord-024061-gxv8y146	282	1	Our	-PRON-	PRP$
cord-024061-gxv8y146	282	2	BF	bf	NN
cord-024061-gxv8y146	282	3	values	value	NNS
cord-024061-gxv8y146	282	4	suggested	suggest	VBD
cord-024061-gxv8y146	282	5	that	that	IN
cord-024061-gxv8y146	282	6	the	the	DT
cord-024061-gxv8y146	282	7	PB2	PB2	NNP
cord-024061-gxv8y146	282	8	sequence	sequence	NN
cord-024061-gxv8y146	282	9	data	datum	NNS
cord-024061-gxv8y146	282	10	favored	favor	VBD
cord-024061-gxv8y146	282	11	the	the	DT
cord-024061-gxv8y146	282	12	asymmetric	asymmetric	JJ
cord-024061-gxv8y146	282	13	model	model	NN
cord-024061-gxv8y146	282	14	with	with	IN
cord-024061-gxv8y146	282	15	the	the	DT
cord-024061-gxv8y146	282	16	SG	SG	NNP
cord-024061-gxv8y146	282	17	prior	prior	RB
cord-024061-gxv8y146	282	18	,	,	,
cord-024061-gxv8y146	282	19	but	but	CC
cord-024061-gxv8y146	282	20	with	with	IN
cord-024061-gxv8y146	282	21	a	a	DT
cord-024061-gxv8y146	282	22	very	very	RB
cord-024061-gxv8y146	282	23	slight	slight	JJ
cord-024061-gxv8y146	282	24	edge	edge	NN
cord-024061-gxv8y146	282	25	over	over	IN
cord-024061-gxv8y146	282	26	the	the	DT
cord-024061-gxv8y146	282	27	symmetric	symmetric	JJ
cord-024061-gxv8y146	282	28	model	model	NN
cord-024061-gxv8y146	282	29	with	with	IN
cord-024061-gxv8y146	282	30	the	the	DT
cord-024061-gxv8y146	282	31	same	same	JJ
cord-024061-gxv8y146	282	32	coalescent	coalescent	NN
cord-024061-gxv8y146	282	33	prior	prior	RB
cord-024061-gxv8y146	282	34	(	(	-LRB-
cord-024061-gxv8y146	282	35	Supplementary	Supplementary	NNP
cord-024061-gxv8y146	282	36	Tables	Tables	NNPS
cord-024061-gxv8y146	282	37	5	5	CD
cord-024061-gxv8y146	282	38	,	,	,
cord-024061-gxv8y146	282	39	6	6	CD
cord-024061-gxv8y146	282	40	)	)	-RRB-
cord-024061-gxv8y146	282	41	.	.	.
cord-024061-gxv8y146	283	1	RSPPs	rspp	NNS
cord-024061-gxv8y146	283	2	inferred	infer	VBN
cord-024061-gxv8y146	283	3	from	from	IN
cord-024061-gxv8y146	283	4	the	the	DT
cord-024061-gxv8y146	283	5	PB2	PB2	NNP
cord-024061-gxv8y146	283	6	segment	segment	NN
cord-024061-gxv8y146	283	7	were	be	VBD
cord-024061-gxv8y146	283	8	almost	almost	RB
cord-024061-gxv8y146	283	9	equal	equal	JJ
cord-024061-gxv8y146	283	10	for	for	IN
cord-024061-gxv8y146	283	11	all	all	DT
cord-024061-gxv8y146	283	12	states	state	NNS
cord-024061-gxv8y146	283	13	and	and	CC
cord-024061-gxv8y146	283	14	,	,	,
cord-024061-gxv8y146	283	15	hence	hence	RB
cord-024061-gxv8y146	283	16	,	,	,
cord-024061-gxv8y146	283	17	were	be	VBD
cord-024061-gxv8y146	283	18	inconclusive	inconclusive	JJ
cord-024061-gxv8y146	283	19	,	,	,
cord-024061-gxv8y146	283	20	when	when	WRB
cord-024061-gxv8y146	283	21	using	use	VBG
cord-024061-gxv8y146	283	22	the	the	DT
cord-024061-gxv8y146	283	23	asymmetric	asymmetric	JJ
cord-024061-gxv8y146	283	24	model	model	NN
cord-024061-gxv8y146	283	25	with	with	IN
cord-024061-gxv8y146	283	26	the	the	DT
cord-024061-gxv8y146	283	27	four	four	CD
cord-024061-gxv8y146	283	28	coalescent	coalescent	NN
cord-024061-gxv8y146	283	29	priors	prior	NNS
cord-024061-gxv8y146	283	30	(	(	-LRB-
cord-024061-gxv8y146	283	31	Figures	figure	NNS
cord-024061-gxv8y146	283	32	6A	6A	NNP
cord-024061-gxv8y146	283	33	-	-	HYPH
cord-024061-gxv8y146	283	34	D	D	NNP
cord-024061-gxv8y146	283	35	)	)	-RRB-
cord-024061-gxv8y146	283	36	.	.	.
cord-024061-gxv8y146	284	1	Similarly	similarly	RB
cord-024061-gxv8y146	284	2	,	,	,
cord-024061-gxv8y146	284	3	using	use	VBG
cord-024061-gxv8y146	284	4	the	the	DT
cord-024061-gxv8y146	284	5	symmetric	symmetric	JJ
cord-024061-gxv8y146	284	6	model	model	NN
cord-024061-gxv8y146	284	7	with	with	IN
cord-024061-gxv8y146	284	8	the	the	DT
cord-024061-gxv8y146	284	9	four	four	CD
cord-024061-gxv8y146	284	10	coalescent	coalescent	NN
cord-024061-gxv8y146	284	11	priors	prior	NNS
cord-024061-gxv8y146	284	12	was	be	VBD
cord-024061-gxv8y146	284	13	inconclusive	inconclusive	JJ
cord-024061-gxv8y146	284	14	in	in	IN
cord-024061-gxv8y146	284	15	terms	term	NNS
cord-024061-gxv8y146	284	16	of	of	IN
cord-024061-gxv8y146	284	17	identifying	identify	VBG
cord-024061-gxv8y146	284	18	the	the	DT
cord-024061-gxv8y146	284	19	ancestral	ancestral	JJ
cord-024061-gxv8y146	284	20	location	location	NN
cord-024061-gxv8y146	284	21	for	for	IN
cord-024061-gxv8y146	284	22	the	the	DT
cord-024061-gxv8y146	284	23	currently	currently	RB
cord-024061-gxv8y146	284	24	circulating	circulate	VBG
cord-024061-gxv8y146	284	25	viral	viral	JJ
cord-024061-gxv8y146	284	26	strains	strain	NNS
cord-024061-gxv8y146	284	27	(	(	-LRB-
cord-024061-gxv8y146	284	28	Figures	figure	NNS
cord-024061-gxv8y146	284	29	6E	6E	NNP
cord-024061-gxv8y146	284	30	-	-	HYPH
cord-024061-gxv8y146	284	31	H	H	NNP
cord-024061-gxv8y146	284	32	)	)	-RRB-
cord-024061-gxv8y146	284	33	.	.	.
cord-024061-gxv8y146	285	1	More	more	RBR
cord-024061-gxv8y146	285	2	specifically	specifically	RB
cord-024061-gxv8y146	285	3	,	,	,
cord-024061-gxv8y146	285	4	the	the	DT
cord-024061-gxv8y146	285	5	magnitude	magnitude	NN
cord-024061-gxv8y146	285	6	of	of	IN
cord-024061-gxv8y146	285	7	differences	difference	NNS
cord-024061-gxv8y146	285	8	between	between	IN
cord-024061-gxv8y146	285	9	Minnesota	Minnesota	NNP
cord-024061-gxv8y146	285	10	and	and	CC
cord-024061-gxv8y146	285	11	Missouri	Missouri	NNP
cord-024061-gxv8y146	285	12	and	and	CC
cord-024061-gxv8y146	285	13	in	in	IN
cord-024061-gxv8y146	285	14	the	the	DT
cord-024061-gxv8y146	285	15	inferred	infer	VBN
cord-024061-gxv8y146	285	16	RSPPs	rspp	NNS
cord-024061-gxv8y146	285	17	,	,	,
cord-024061-gxv8y146	285	18	across	across	IN
cord-024061-gxv8y146	285	19	different	different	JJ
cord-024061-gxv8y146	285	20	coalescent	coalescent	NN
cord-024061-gxv8y146	285	21	priors	prior	NNS
cord-024061-gxv8y146	285	22	,	,	,
cord-024061-gxv8y146	285	23	was	be	VBD
cord-024061-gxv8y146	285	24	substantially	substantially	RB
cord-024061-gxv8y146	285	25	small	small	JJ
cord-024061-gxv8y146	285	26	(	(	-LRB-
cord-024061-gxv8y146	285	27	Figures	figure	NNS
cord-024061-gxv8y146	285	28	6E	6E	NNP
cord-024061-gxv8y146	285	29	-	-	HYPH
cord-024061-gxv8y146	285	30	H	H	NNP
cord-024061-gxv8y146	285	31	)	)	-RRB-
cord-024061-gxv8y146	285	32	.	.	.
cord-024061-gxv8y146	286	1	For	for	IN
cord-024061-gxv8y146	286	2	example	example	NN
cord-024061-gxv8y146	286	3	,	,	,
cord-024061-gxv8y146	286	4	when	when	WRB
cord-024061-gxv8y146	286	5	using	use	VBG
cord-024061-gxv8y146	286	6	the	the	DT
cord-024061-gxv8y146	286	7	SG	SG	NNP
cord-024061-gxv8y146	286	8	prior	prior	RB
cord-024061-gxv8y146	286	9	,	,	,
cord-024061-gxv8y146	286	10	the	the	DT
cord-024061-gxv8y146	286	11	inferred	infer	VBN
cord-024061-gxv8y146	286	12	RSPPs	rspp	NNS
cord-024061-gxv8y146	286	13	were	be	VBD
cord-024061-gxv8y146	286	14	0.18	0.18	CD
cord-024061-gxv8y146	286	15	and	and	CC
cord-024061-gxv8y146	286	16	0.22	0.22	CD
cord-024061-gxv8y146	286	17	for	for	IN
cord-024061-gxv8y146	286	18	Missouri	Missouri	NNP
cord-024061-gxv8y146	286	19	and	and	CC
cord-024061-gxv8y146	286	20	Minnesota	Minnesota	NNP
cord-024061-gxv8y146	286	21	,	,	,
cord-024061-gxv8y146	286	22	respectively	respectively	RB
cord-024061-gxv8y146	286	23	(	(	-LRB-
cord-024061-gxv8y146	286	24	Figure	figure	NN
cord-024061-gxv8y146	286	25	6H	6h	CD
cord-024061-gxv8y146	286	26	)	)	-RRB-
cord-024061-gxv8y146	286	27	.	.	.
cord-024061-gxv8y146	287	1	Our	-PRON-	PRP$
cord-024061-gxv8y146	287	2	BF	bf	NN
cord-024061-gxv8y146	287	3	-	-	HYPH
cord-024061-gxv8y146	287	4	BSSVS	bssvs	NN
cord-024061-gxv8y146	287	5	analyses	analysis	NNS
cord-024061-gxv8y146	287	6	,	,	,
cord-024061-gxv8y146	287	7	using	use	VBG
cord-024061-gxv8y146	287	8	the	the	DT
cord-024061-gxv8y146	287	9	asymmetric	asymmetric	JJ
cord-024061-gxv8y146	287	10	model	model	NN
cord-024061-gxv8y146	287	11	with	with	IN
cord-024061-gxv8y146	287	12	the	the	DT
cord-024061-gxv8y146	287	13	CP	cp	NN
cord-024061-gxv8y146	287	14	and	and	CC
cord-024061-gxv8y146	287	15	the	the	DT
cord-024061-gxv8y146	287	16	EX	ex	NN
cord-024061-gxv8y146	287	17	coalescent	coalescent	NN
cord-024061-gxv8y146	287	18	priors	prior	NNS
cord-024061-gxv8y146	287	19	for	for	IN
cord-024061-gxv8y146	287	20	the	the	DT
cord-024061-gxv8y146	287	21	HA	HA	NNP
cord-024061-gxv8y146	287	22	gene	gene	NN
cord-024061-gxv8y146	287	23	segment	segment	NN
cord-024061-gxv8y146	287	24	,	,	,
cord-024061-gxv8y146	287	25	suggest	suggest	VBP
cord-024061-gxv8y146	287	26	that	that	IN
cord-024061-gxv8y146	287	27	the	the	DT
cord-024061-gxv8y146	287	28	top	top	JJ
cord-024061-gxv8y146	287	29	three	three	CD
cord-024061-gxv8y146	287	30	most	most	RBS
cord-024061-gxv8y146	287	31	significant	significant	JJ
cord-024061-gxv8y146	287	32	unidirectional	unidirectional	JJ
cord-024061-gxv8y146	287	33	routes	route	NNS
cord-024061-gxv8y146	287	34	of	of	IN
cord-024061-gxv8y146	287	35	viral	viral	JJ
cord-024061-gxv8y146	287	36	dispersal	dispersal	NN
cord-024061-gxv8y146	287	37	(	(	-LRB-
cord-024061-gxv8y146	287	38	BF	BF	NNP
cord-024061-gxv8y146	287	39	>	>	XX
cord-024061-gxv8y146	287	40	18	18	CD
cord-024061-gxv8y146	287	41	)	)	-RRB-
cord-024061-gxv8y146	287	42	were	be	VBD
cord-024061-gxv8y146	287	43	between	between	IN
cord-024061-gxv8y146	287	44	Minnesota	Minnesota	NNP
cord-024061-gxv8y146	287	45	,	,	,
cord-024061-gxv8y146	287	46	Iowa	Iowa	NNP
cord-024061-gxv8y146	287	47	,	,	,
cord-024061-gxv8y146	287	48	Illinois	Illinois	NNP
cord-024061-gxv8y146	287	49	,	,	,
cord-024061-gxv8y146	287	50	and	and	CC
cord-024061-gxv8y146	287	51	Missouri	Missouri	NNP
cord-024061-gxv8y146	287	52	(	(	-LRB-
cord-024061-gxv8y146	287	53	Figures	figure	NNS
cord-024061-gxv8y146	287	54	7A	7a	NN
cord-024061-gxv8y146	287	55	,	,	,
cord-024061-gxv8y146	287	56	B	b	NN
cord-024061-gxv8y146	287	57	)	)	-RRB-
cord-024061-gxv8y146	287	58	.	.	.
cord-024061-gxv8y146	288	1	The	the	DT
cord-024061-gxv8y146	288	2	inferred	infer	VBN
cord-024061-gxv8y146	288	3	routes	route	NNS
cord-024061-gxv8y146	288	4	maintained	maintain	VBD
cord-024061-gxv8y146	288	5	their	-PRON-	PRP$
cord-024061-gxv8y146	288	6	unidirectionality	unidirectionality	NN
cord-024061-gxv8y146	288	7	from	from	IN
cord-024061-gxv8y146	288	8	the	the	DT
cord-024061-gxv8y146	288	9	origin	origin	NN
cord-024061-gxv8y146	288	10	to	to	IN
cord-024061-gxv8y146	288	11	the	the	DT
cord-024061-gxv8y146	288	12	destination	destination	JJ
cord-024061-gxv8y146	288	13	geographical	geographical	JJ
cord-024061-gxv8y146	288	14	locations	location	NNS
cord-024061-gxv8y146	288	15	,	,	,
cord-024061-gxv8y146	288	16	using	use	VBG
cord-024061-gxv8y146	288	17	CP	CP	NNP
cord-024061-gxv8y146	288	18	and	and	CC
cord-024061-gxv8y146	288	19	EX	EX	NNP
cord-024061-gxv8y146	288	20	priors	prior	NNS
cord-024061-gxv8y146	288	21	(	(	-LRB-
cord-024061-gxv8y146	288	22	Figures	figure	NNS
cord-024061-gxv8y146	288	23	7A	7a	NN
cord-024061-gxv8y146	288	24	,	,	,
cord-024061-gxv8y146	288	25	B	b	NN
cord-024061-gxv8y146	288	26	)	)	-RRB-
cord-024061-gxv8y146	288	27	.	.	.
cord-024061-gxv8y146	289	1	Similarly	similarly	RB
cord-024061-gxv8y146	289	2	,	,	,
cord-024061-gxv8y146	289	3	the	the	DT
cord-024061-gxv8y146	289	4	order	order	NN
cord-024061-gxv8y146	289	5	of	of	IN
cord-024061-gxv8y146	289	6	statistical	statistical	JJ
cord-024061-gxv8y146	289	7	significance	significance	NN
cord-024061-gxv8y146	289	8	suggests	suggest	VBZ
cord-024061-gxv8y146	289	9	that	that	IN
cord-024061-gxv8y146	289	10	the	the	DT
cord-024061-gxv8y146	289	11	route	route	NN
cord-024061-gxv8y146	289	12	from	from	IN
cord-024061-gxv8y146	289	13	Iowa	Iowa	NNP
cord-024061-gxv8y146	289	14	to	to	IN
cord-024061-gxv8y146	289	15	Minnesota	Minnesota	NNP
cord-024061-gxv8y146	289	16	is	be	VBZ
cord-024061-gxv8y146	289	17	the	the	DT
cord-024061-gxv8y146	289	18	most	most	RBS
cord-024061-gxv8y146	289	19	important	important	JJ
cord-024061-gxv8y146	289	20	for	for	IN
cord-024061-gxv8y146	289	21	viral	viral	JJ
cord-024061-gxv8y146	289	22	dispersal	dispersal	NN
cord-024061-gxv8y146	289	23	between	between	IN
cord-024061-gxv8y146	289	24	states	state	NNS
cord-024061-gxv8y146	289	25	(	(	-LRB-
cord-024061-gxv8y146	289	26	Figures	figure	NNS
cord-024061-gxv8y146	289	27	7A	7a	NN
cord-024061-gxv8y146	289	28	,	,	,
cord-024061-gxv8y146	289	29	B	b	NN
cord-024061-gxv8y146	289	30	)	)	-RRB-
cord-024061-gxv8y146	289	31	.	.	.
cord-024061-gxv8y146	290	1	In	in	IN
cord-024061-gxv8y146	290	2	contrast	contrast	NN
cord-024061-gxv8y146	290	3	,	,	,
cord-024061-gxv8y146	290	4	the	the	DT
cord-024061-gxv8y146	290	5	EXg	EXg	NNS
cord-024061-gxv8y146	290	6	with	with	IN
cord-024061-gxv8y146	290	7	the	the	DT
cord-024061-gxv8y146	290	8	asymmetric	asymmetric	JJ
cord-024061-gxv8y146	290	9	model	model	NN
cord-024061-gxv8y146	290	10	suggests	suggest	VBZ
cord-024061-gxv8y146	290	11	that	that	IN
cord-024061-gxv8y146	290	12	the	the	DT
cord-024061-gxv8y146	290	13	route	route	NN
cord-024061-gxv8y146	290	14	from	from	IN
cord-024061-gxv8y146	290	15	Ohia	Ohia	NNP
cord-024061-gxv8y146	290	16	to	to	IN
cord-024061-gxv8y146	290	17	Indiana	Indiana	NNP
cord-024061-gxv8y146	290	18	is	be	VBZ
cord-024061-gxv8y146	290	19	substantially	substantially	RB
cord-024061-gxv8y146	290	20	the	the	DT
cord-024061-gxv8y146	290	21	most	most	RBS
cord-024061-gxv8y146	290	22	significant	significant	JJ
cord-024061-gxv8y146	290	23	dispersal	dispersal	NN
cord-024061-gxv8y146	290	24	route	route	NN
cord-024061-gxv8y146	290	25	(	(	-LRB-
cord-024061-gxv8y146	290	26	BSSVS	BSSVS	NNP
cord-024061-gxv8y146	290	27	-	-	HYPH
cord-024061-gxv8y146	290	28	BF	bf	NN
cord-024061-gxv8y146	290	29	=	=	SYM
cord-024061-gxv8y146	290	30	1,157	1,157	CD
cord-024061-gxv8y146	290	31	)	)	-RRB-
cord-024061-gxv8y146	290	32	(	(	-LRB-
cord-024061-gxv8y146	290	33	Figure	Figure	NNP
cord-024061-gxv8y146	290	34	7C	7C	NNP
cord-024061-gxv8y146	290	35	)	)	-RRB-
cord-024061-gxv8y146	290	36	.	.	.
cord-024061-gxv8y146	291	1	Nevertheless	nevertheless	RB
cord-024061-gxv8y146	291	2	,	,	,
cord-024061-gxv8y146	291	3	the	the	DT
cord-024061-gxv8y146	291	4	SG	SG	NNP
cord-024061-gxv8y146	291	5	prior	prior	RB
cord-024061-gxv8y146	291	6	agrees	agree	VBZ
cord-024061-gxv8y146	291	7	with	with	IN
cord-024061-gxv8y146	291	8	the	the	DT
cord-024061-gxv8y146	291	9	results	result	NNS
cord-024061-gxv8y146	291	10	of	of	IN
cord-024061-gxv8y146	291	11	the	the	DT
cord-024061-gxv8y146	291	12	CP	CP	NNP
cord-024061-gxv8y146	291	13	and	and	CC
cord-024061-gxv8y146	291	14	EX	EX	NNP
cord-024061-gxv8y146	291	15	priors	prior	NNS
cord-024061-gxv8y146	291	16	in	in	IN
cord-024061-gxv8y146	291	17	inferring	infer	VBG
cord-024061-gxv8y146	291	18	the	the	DT
cord-024061-gxv8y146	291	19	route	route	NN
cord-024061-gxv8y146	291	20	from	from	IN
cord-024061-gxv8y146	291	21	Iowa	Iowa	NNP
cord-024061-gxv8y146	291	22	to	to	IN
cord-024061-gxv8y146	291	23	Minnesota	Minnesota	NNP
cord-024061-gxv8y146	291	24	as	as	IN
cord-024061-gxv8y146	291	25	the	the	DT
cord-024061-gxv8y146	291	26	most	most	RBS
cord-024061-gxv8y146	291	27	significant	significant	JJ
cord-024061-gxv8y146	291	28	(	(	-LRB-
cord-024061-gxv8y146	291	29	BSSVS	BSSVS	NNP
cord-024061-gxv8y146	291	30	-	-	HYPH
cord-024061-gxv8y146	291	31	BF	bf	NN
cord-024061-gxv8y146	291	32	=	=	SYM
cord-024061-gxv8y146	291	33	37	37	CD
cord-024061-gxv8y146	291	34	)	)	-RRB-
cord-024061-gxv8y146	291	35	(	(	-LRB-
cord-024061-gxv8y146	291	36	Figure	Figure	NNP
cord-024061-gxv8y146	291	37	7D	7D	NNP
cord-024061-gxv8y146	291	38	)	)	-RRB-
cord-024061-gxv8y146	291	39	,	,	,
cord-024061-gxv8y146	291	40	while	while	IN
cord-024061-gxv8y146	291	41	inferences	inference	NNS
cord-024061-gxv8y146	291	42	from	from	IN
cord-024061-gxv8y146	291	43	the	the	DT
cord-024061-gxv8y146	291	44	symmetric	symmetric	JJ
cord-024061-gxv8y146	291	45	model	model	NN
cord-024061-gxv8y146	291	46	and	and	CC
cord-024061-gxv8y146	291	47	the	the	DT
cord-024061-gxv8y146	291	48	four	four	CD
cord-024061-gxv8y146	291	49	coalescent	coalescent	NN
cord-024061-gxv8y146	291	50	priors	prior	NNS
cord-024061-gxv8y146	291	51	consistently	consistently	RB
cord-024061-gxv8y146	291	52	agreed	agree	VBD
cord-024061-gxv8y146	291	53	that	that	IN
cord-024061-gxv8y146	291	54	the	the	DT
cord-024061-gxv8y146	291	55	top	top	JJ
cord-024061-gxv8y146	291	56	most	most	RBS
cord-024061-gxv8y146	291	57	significant	significant	JJ
cord-024061-gxv8y146	291	58	bidirectional	bidirectional	JJ
cord-024061-gxv8y146	291	59	route	route	NN
cord-024061-gxv8y146	291	60	of	of	IN
cord-024061-gxv8y146	291	61	viral	viral	JJ
cord-024061-gxv8y146	291	62	dispersal	dispersal	NN
cord-024061-gxv8y146	291	63	(	(	-LRB-
cord-024061-gxv8y146	291	64	BF	BF	NNP
cord-024061-gxv8y146	291	65	≥	≥	NNP
cord-024061-gxv8y146	291	66	990	990	CD
cord-024061-gxv8y146	291	67	)	)	-RRB-
cord-024061-gxv8y146	291	68	was	be	VBD
cord-024061-gxv8y146	291	69	between	between	IN
cord-024061-gxv8y146	291	70	Indiana	Indiana	NNP
cord-024061-gxv8y146	291	71	and	and	CC
cord-024061-gxv8y146	291	72	Ohio	Ohio	NNP
cord-024061-gxv8y146	292	1	(	(	-LRB-
cord-024061-gxv8y146	292	2	Figures	figure	NNS
cord-024061-gxv8y146	292	3	7E	7E	NNP
cord-024061-gxv8y146	292	4	-	-	HYPH
cord-024061-gxv8y146	292	5	H	H	NNP
cord-024061-gxv8y146	292	6	)	)	-RRB-
cord-024061-gxv8y146	292	7	.	.	.
cord-024061-gxv8y146	293	1	However	however	RB
cord-024061-gxv8y146	293	2	,	,	,
cord-024061-gxv8y146	293	3	disagreements	disagreement	NNS
cord-024061-gxv8y146	293	4	were	be	VBD
cord-024061-gxv8y146	293	5	inferred	infer	VBN
cord-024061-gxv8y146	293	6	on	on	IN
cord-024061-gxv8y146	293	7	the	the	DT
cord-024061-gxv8y146	293	8	second	second	JJ
cord-024061-gxv8y146	293	9	and	and	CC
cord-024061-gxv8y146	293	10	the	the	DT
cord-024061-gxv8y146	293	11	third	third	JJ
cord-024061-gxv8y146	293	12	most	most	RBS
cord-024061-gxv8y146	293	13	significant	significant	JJ
cord-024061-gxv8y146	293	14	routes	route	NNS
cord-024061-gxv8y146	293	15	when	when	WRB
cord-024061-gxv8y146	293	16	using	use	VBG
cord-024061-gxv8y146	293	17	the	the	DT
cord-024061-gxv8y146	293	18	CP	CP	NNP
cord-024061-gxv8y146	293	19	and	and	CC
cord-024061-gxv8y146	293	20	EX	EX	NNP
cord-024061-gxv8y146	293	21	on	on	IN
cord-024061-gxv8y146	293	22	one	one	CD
cord-024061-gxv8y146	293	23	side	side	NN
cord-024061-gxv8y146	293	24	and	and	CC
cord-024061-gxv8y146	293	25	EXg	exg	NN
cord-024061-gxv8y146	293	26	and	and	CC
cord-024061-gxv8y146	293	27	SG	SG	NNP
cord-024061-gxv8y146	293	28	on	on	IN
cord-024061-gxv8y146	293	29	the	the	DT
cord-024061-gxv8y146	293	30	other	other	JJ
cord-024061-gxv8y146	293	31	(	(	-LRB-
cord-024061-gxv8y146	293	32	Figure	figure	NN
cord-024061-gxv8y146	293	33	7H	7h	CD
cord-024061-gxv8y146	293	34	)	)	-RRB-
cord-024061-gxv8y146	293	35	.	.	.
cord-024061-gxv8y146	294	1	Dispersal	dispersal	NN
cord-024061-gxv8y146	294	2	routes	route	NNS
cord-024061-gxv8y146	294	3	inferred	infer	VBN
cord-024061-gxv8y146	294	4	for	for	IN
cord-024061-gxv8y146	294	5	PB2	PB2	NNP
cord-024061-gxv8y146	294	6	(	(	-LRB-
cord-024061-gxv8y146	294	7	including	include	VBG
cord-024061-gxv8y146	294	8	the	the	DT
cord-024061-gxv8y146	294	9	order	order	NN
cord-024061-gxv8y146	294	10	of	of	IN
cord-024061-gxv8y146	294	11	significance	significance	NN
cord-024061-gxv8y146	294	12	)	)	-RRB-
cord-024061-gxv8y146	294	13	were	be	VBD
cord-024061-gxv8y146	294	14	also	also	RB
cord-024061-gxv8y146	294	15	sensitive	sensitive	JJ
cord-024061-gxv8y146	294	16	to	to	IN
cord-024061-gxv8y146	294	17	the	the	DT
cord-024061-gxv8y146	294	18	selected	select	VBN
cord-024061-gxv8y146	294	19	discrete	discrete	JJ
cord-024061-gxv8y146	294	20	spatial	spatial	JJ
cord-024061-gxv8y146	294	21	model	model	NN
cord-024061-gxv8y146	294	22	and	and	CC
cord-024061-gxv8y146	294	23	slightly	slightly	RB
cord-024061-gxv8y146	294	24	to	to	IN
cord-024061-gxv8y146	294	25	the	the	DT
cord-024061-gxv8y146	294	26	coalescent	coalescent	JJ
cord-024061-gxv8y146	294	27	priors	prior	NNS
cord-024061-gxv8y146	294	28	(	(	-LRB-
cord-024061-gxv8y146	294	29	Figure	figure	NN
cord-024061-gxv8y146	294	30	8)	8)	NN
cord-024061-gxv8y146	294	31	.	.	.
cord-024061-gxv8y146	295	1	Thus	thus	RB
cord-024061-gxv8y146	295	2	,	,	,
cord-024061-gxv8y146	295	3	when	when	WRB
cord-024061-gxv8y146	295	4	using	use	VBG
cord-024061-gxv8y146	295	5	the	the	DT
cord-024061-gxv8y146	295	6	asymmetric	asymmetric	JJ
cord-024061-gxv8y146	295	7	model	model	NN
cord-024061-gxv8y146	295	8	,	,	,
cord-024061-gxv8y146	295	9	the	the	DT
cord-024061-gxv8y146	295	10	top	top	JJ
cord-024061-gxv8y146	295	11	two	two	CD
cord-024061-gxv8y146	295	12	unidirectional	unidirectional	JJ
cord-024061-gxv8y146	295	13	routes	route	NNS
cord-024061-gxv8y146	295	14	included	include	VBN
cord-024061-gxv8y146	295	15	(	(	-LRB-
cord-024061-gxv8y146	295	16	1	1	CD
cord-024061-gxv8y146	295	17	)	)	-RRB-
cord-024061-gxv8y146	295	18	Iowa	Iowa	NNP
cord-024061-gxv8y146	295	19	→	→	SYM
cord-024061-gxv8y146	295	20	Minnesota	Minnesota	NNP
cord-024061-gxv8y146	295	21	;	;	:
cord-024061-gxv8y146	295	22	(	(	-LRB-
cord-024061-gxv8y146	295	23	2	2	LS
cord-024061-gxv8y146	295	24	)	)	-RRB-
cord-024061-gxv8y146	295	25	Indiana	Indiana	NNP
cord-024061-gxv8y146	295	26	→	→	SYM
cord-024061-gxv8y146	295	27	Kentucky	Kentucky	NNP
cord-024061-gxv8y146	295	28	(	(	-LRB-
cord-024061-gxv8y146	295	29	Figures	figure	NNS
cord-024061-gxv8y146	295	30	8A	8a	NN
cord-024061-gxv8y146	295	31	-	-	HYPH
cord-024061-gxv8y146	295	32	D	D	NNP
cord-024061-gxv8y146	295	33	)	)	-RRB-
cord-024061-gxv8y146	295	34	.	.	.
cord-024061-gxv8y146	296	1	While	while	IN
cord-024061-gxv8y146	296	2	the	the	DT
cord-024061-gxv8y146	296	3	CP	cp	NN
cord-024061-gxv8y146	296	4	,	,	,
cord-024061-gxv8y146	296	5	EX	EX	NNP
cord-024061-gxv8y146	296	6	,	,	,
cord-024061-gxv8y146	296	7	and	and	CC
cord-024061-gxv8y146	296	8	EXg	EXg	NNS
cord-024061-gxv8y146	296	9	inferred	infer	VBD
cord-024061-gxv8y146	296	10	the	the	DT
cord-024061-gxv8y146	296	11	route	route	NN
cord-024061-gxv8y146	296	12	from	from	IN
cord-024061-gxv8y146	296	13	Illinois	Illinois	NNP
cord-024061-gxv8y146	296	14	to	to	IN
cord-024061-gxv8y146	296	15	Missouri	Missouri	NNP
cord-024061-gxv8y146	296	16	as	as	IN
cord-024061-gxv8y146	296	17	the	the	DT
cord-024061-gxv8y146	296	18	third	third	JJ
cord-024061-gxv8y146	296	19	most	most	RBS
cord-024061-gxv8y146	296	20	significant	significant	JJ
cord-024061-gxv8y146	296	21	route	route	NN
cord-024061-gxv8y146	296	22	(	(	-LRB-
cord-024061-gxv8y146	296	23	Figures	figure	NNS
cord-024061-gxv8y146	296	24	8A	8a	NN
cord-024061-gxv8y146	296	25	-	-	HYPH
cord-024061-gxv8y146	296	26	C	C	NNP
cord-024061-gxv8y146	296	27	)	)	-RRB-
cord-024061-gxv8y146	296	28	,	,	,
cord-024061-gxv8y146	296	29	the	the	DT
cord-024061-gxv8y146	296	30	SG	SG	NNP
cord-024061-gxv8y146	296	31	prior	prior	RB
cord-024061-gxv8y146	296	32	inferred	infer	VBD
cord-024061-gxv8y146	296	33	the	the	DT
cord-024061-gxv8y146	296	34	route	route	NN
cord-024061-gxv8y146	296	35	from	from	IN
cord-024061-gxv8y146	296	36	Ohio	Ohio	NNP
cord-024061-gxv8y146	296	37	to	to	IN
cord-024061-gxv8y146	296	38	Indiana	Indiana	NNP
cord-024061-gxv8y146	296	39	as	as	IN
cord-024061-gxv8y146	296	40	the	the	DT
cord-024061-gxv8y146	296	41	third	third	JJ
cord-024061-gxv8y146	296	42	most	most	RBS
cord-024061-gxv8y146	296	43	significant	significant	JJ
cord-024061-gxv8y146	296	44	route	route	NN
cord-024061-gxv8y146	296	45	(	(	-LRB-
cord-024061-gxv8y146	296	46	Figure	figure	NN
cord-024061-gxv8y146	296	47	8D	8d	NN
cord-024061-gxv8y146	296	48	)	)	-RRB-
cord-024061-gxv8y146	296	49	.	.	.
cord-024061-gxv8y146	297	1	Finally	finally	RB
cord-024061-gxv8y146	297	2	,	,	,
cord-024061-gxv8y146	297	3	our	-PRON-	PRP$
cord-024061-gxv8y146	297	4	inferred	infer	VBN
cord-024061-gxv8y146	297	5	top	top	JJ
cord-024061-gxv8y146	297	6	three	three	CD
cord-024061-gxv8y146	297	7	significant	significant	JJ
cord-024061-gxv8y146	297	8	dispersal	dispersal	NN
cord-024061-gxv8y146	297	9	routes	route	NNS
cord-024061-gxv8y146	297	10	were	be	VBD
cord-024061-gxv8y146	297	11	from	from	IN
cord-024061-gxv8y146	297	12	the	the	DT
cord-024061-gxv8y146	297	13	symmetric	symmetric	JJ
cord-024061-gxv8y146	297	14	model	model	NN
cord-024061-gxv8y146	297	15	between	between	IN
cord-024061-gxv8y146	297	16	(	(	-LRB-
cord-024061-gxv8y146	297	17	1	1	CD
cord-024061-gxv8y146	297	18	)	)	-RRB-
cord-024061-gxv8y146	297	19	Indiana	Indiana	NNP
cord-024061-gxv8y146	297	20	and	and	CC
cord-024061-gxv8y146	297	21	Ohio	Ohio	NNP
cord-024061-gxv8y146	297	22	;	;	:
cord-024061-gxv8y146	297	23	(	(	-LRB-
cord-024061-gxv8y146	297	24	2	2	LS
cord-024061-gxv8y146	297	25	)	)	-RRB-
cord-024061-gxv8y146	297	26	Minnesota	Minnesota	NNP
cord-024061-gxv8y146	297	27	and	and	CC
cord-024061-gxv8y146	297	28	Iowa	Iowa	NNP
cord-024061-gxv8y146	297	29	;	;	:
cord-024061-gxv8y146	297	30	(	(	-LRB-
cord-024061-gxv8y146	297	31	3	3	LS
cord-024061-gxv8y146	297	32	)	)	-RRB-
cord-024061-gxv8y146	297	33	Indiana	Indiana	NNP
cord-024061-gxv8y146	297	34	and	and	CC
cord-024061-gxv8y146	297	35	Kentucky	Kentucky	NNP
cord-024061-gxv8y146	297	36	(	(	-LRB-
cord-024061-gxv8y146	297	37	Figures	figure	NNS
cord-024061-gxv8y146	297	38	8E	8e	VBP
cord-024061-gxv8y146	297	39	-	-	HYPH
cord-024061-gxv8y146	297	40	H	H	NNP
cord-024061-gxv8y146	297	41	)	)	-RRB-
cord-024061-gxv8y146	297	42	.	.	.
cord-024061-gxv8y146	298	1	In	in	IN
cord-024061-gxv8y146	298	2	the	the	DT
cord-024061-gxv8y146	298	3	past	past	JJ
cord-024061-gxv8y146	298	4	decade	decade	NN
cord-024061-gxv8y146	298	5	,	,	,
cord-024061-gxv8y146	298	6	our	-PRON-	PRP$
cord-024061-gxv8y146	298	7	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	298	8	pipeline	pipeline	NN
cord-024061-gxv8y146	298	9	became	become	VBD
cord-024061-gxv8y146	298	10	wellestablished	wellestablished	JJ
cord-024061-gxv8y146	298	11	and	and	CC
cord-024061-gxv8y146	298	12	demonstrated	demonstrate	VBD
cord-024061-gxv8y146	298	13	powerful	powerful	JJ
cord-024061-gxv8y146	298	14	potentials	potential	NNS
cord-024061-gxv8y146	298	15	to	to	TO
cord-024061-gxv8y146	298	16	trace	trace	VB
cord-024061-gxv8y146	298	17	the	the	DT
cord-024061-gxv8y146	298	18	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	298	19	history	history	NN
cord-024061-gxv8y146	298	20	of	of	IN
cord-024061-gxv8y146	298	21	both	both	DT
cord-024061-gxv8y146	298	22	animal	animal	NN
cord-024061-gxv8y146	298	23	and	and	CC
cord-024061-gxv8y146	298	24	human	human	JJ
cord-024061-gxv8y146	298	25	pathogens	pathogen	NNS
cord-024061-gxv8y146	298	26	making	make	VBG
cord-024061-gxv8y146	298	27	it	-PRON-	PRP
cord-024061-gxv8y146	298	28	an	an	DT
cord-024061-gxv8y146	298	29	ideal	ideal	JJ
cord-024061-gxv8y146	298	30	tool	tool	NN
cord-024061-gxv8y146	298	31	for	for	IN
cord-024061-gxv8y146	298	32	designing	design	VBG
cord-024061-gxv8y146	298	33	new	new	JJ
cord-024061-gxv8y146	298	34	molecular	molecular	JJ
cord-024061-gxv8y146	298	35	surveillance	surveillance	NN
cord-024061-gxv8y146	298	36	systems	system	NNS
cord-024061-gxv8y146	298	37	.	.	.
cord-024061-gxv8y146	299	1	In	in	IN
cord-024061-gxv8y146	299	2	this	this	DT
cord-024061-gxv8y146	299	3	study	study	NN
cord-024061-gxv8y146	299	4	,	,	,
cord-024061-gxv8y146	299	5	we	-PRON-	PRP
cord-024061-gxv8y146	299	6	revisited	revisit	VBD
cord-024061-gxv8y146	299	7	essential	essential	JJ
cord-024061-gxv8y146	299	8	concepts	concept	NNS
cord-024061-gxv8y146	299	9	and	and	CC
cord-024061-gxv8y146	299	10	definitions	definition	NNS
cord-024061-gxv8y146	299	11	within	within	IN
cord-024061-gxv8y146	299	12	the	the	DT
cord-024061-gxv8y146	299	13	field	field	NN
cord-024061-gxv8y146	299	14	of	of	IN
cord-024061-gxv8y146	299	15	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	299	16	methods	method	NNS
cord-024061-gxv8y146	299	17	.	.	.
cord-024061-gxv8y146	300	1	Also	also	RB
cord-024061-gxv8y146	300	2	,	,	,
cord-024061-gxv8y146	300	3	we	-PRON-	PRP
cord-024061-gxv8y146	300	4	challenged	challenge	VBD
cord-024061-gxv8y146	300	5	the	the	DT
cord-024061-gxv8y146	300	6	robustness	robustness	NN
cord-024061-gxv8y146	300	7	of	of	IN
cord-024061-gxv8y146	300	8	the	the	DT
cord-024061-gxv8y146	300	9	posterior	posterior	JJ
cord-024061-gxv8y146	300	10	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	300	11	parameters	parameter	NNS
cord-024061-gxv8y146	300	12	,	,	,
cord-024061-gxv8y146	300	13	inferred	infer	VBN
cord-024061-gxv8y146	300	14	by	by	IN
cord-024061-gxv8y146	300	15	the	the	DT
cord-024061-gxv8y146	300	16	commonly	commonly	RB
cord-024061-gxv8y146	300	17	used	use	VBN
cord-024061-gxv8y146	300	18	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	300	19	models	model	NNS
cord-024061-gxv8y146	300	20	,	,	,
cord-024061-gxv8y146	300	21	using	use	VBG
cord-024061-gxv8y146	300	22	two	two	CD
cord-024061-gxv8y146	300	23	gene	gene	NN
cord-024061-gxv8y146	300	24	segments	segment	NNS
cord-024061-gxv8y146	300	25	,	,	,
cord-024061-gxv8y146	300	26	of	of	IN
cord-024061-gxv8y146	300	27	the	the	DT
cord-024061-gxv8y146	300	28	currently	currently	RB
cord-024061-gxv8y146	300	29	circulating	circulate	VBG
cord-024061-gxv8y146	300	30	human	human	NN
cord-024061-gxv8y146	300	31	-	-	HYPH
cord-024061-gxv8y146	300	32	like	like	JJ
cord-024061-gxv8y146	300	33	H3	H3	NNP
cord-024061-gxv8y146	300	34	SI	SI	NNP
cord-024061-gxv8y146	300	35	viruses	virus	NNS
cord-024061-gxv8y146	300	36	isolated	isolate	VBN
cord-024061-gxv8y146	300	37	in	in	IN
cord-024061-gxv8y146	300	38	the	the	DT
cord-024061-gxv8y146	300	39	United	United	NNP
cord-024061-gxv8y146	300	40	States	States	NNP
cord-024061-gxv8y146	300	41	,	,	,
cord-024061-gxv8y146	300	42	and	and	CC
cord-024061-gxv8y146	300	43	multiple	multiple	JJ
cord-024061-gxv8y146	300	44	priors	prior	NNS
cord-024061-gxv8y146	300	45	.	.	.
cord-024061-gxv8y146	301	1	Subsequently	subsequently	RB
cord-024061-gxv8y146	301	2	,	,	,
cord-024061-gxv8y146	301	3	we	-PRON-	PRP
cord-024061-gxv8y146	301	4	compared	compare	VBD
cord-024061-gxv8y146	301	5	similarities	similarity	NNS
cord-024061-gxv8y146	301	6	and	and	CC
cord-024061-gxv8y146	301	7	differences	difference	NNS
cord-024061-gxv8y146	301	8	between	between	IN
cord-024061-gxv8y146	301	9	the	the	DT
cord-024061-gxv8y146	301	10	posterior	posterior	JJ
cord-024061-gxv8y146	301	11	parameters	parameter	NNS
cord-024061-gxv8y146	301	12	inferred	infer	VBN
cord-024061-gxv8y146	301	13	from	from	IN
cord-024061-gxv8y146	301	14	HA	HA	NNP
cord-024061-gxv8y146	301	15	and	and	CC
cord-024061-gxv8y146	301	16	PB2	PB2	NNP
cord-024061-gxv8y146	301	17	sequence	sequence	NN
cord-024061-gxv8y146	301	18	data	datum	NNS
cord-024061-gxv8y146	301	19	using	use	VBG
cord-024061-gxv8y146	301	20	multiple	multiple	JJ
cord-024061-gxv8y146	301	21	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	301	22	models	model	NNS
cord-024061-gxv8y146	301	23	.	.	.
cord-024061-gxv8y146	302	1	Hence	hence	RB
cord-024061-gxv8y146	302	2	,	,	,
cord-024061-gxv8y146	302	3	we	-PRON-	PRP
cord-024061-gxv8y146	302	4	explored	explore	VBD
cord-024061-gxv8y146	302	5	the	the	DT
cord-024061-gxv8y146	302	6	robust	robust	JJ
cord-024061-gxv8y146	302	7	and	and	CC
cord-024061-gxv8y146	302	8	sensitive	sensitive	JJ
cord-024061-gxv8y146	302	9	aspects	aspect	NNS
cord-024061-gxv8y146	302	10	of	of	IN
cord-024061-gxv8y146	302	11	SI	SI	NNP
cord-024061-gxv8y146	302	12	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	302	13	models	model	NNS
cord-024061-gxv8y146	302	14	and	and	CC
cord-024061-gxv8y146	302	15	highlighted	highlight	VBD
cord-024061-gxv8y146	302	16	the	the	DT
cord-024061-gxv8y146	302	17	importance	importance	NN
cord-024061-gxv8y146	302	18	of	of	IN
cord-024061-gxv8y146	302	19	model	model	NN
cord-024061-gxv8y146	302	20	selection	selection	NN
cord-024061-gxv8y146	302	21	within	within	IN
cord-024061-gxv8y146	302	22	their	-PRON-	PRP$
cord-024061-gxv8y146	302	23	analytical	analytical	JJ
cord-024061-gxv8y146	302	24	framework	framework	NN
cord-024061-gxv8y146	302	25	.	.	.
cord-024061-gxv8y146	303	1	However	however	RB
cord-024061-gxv8y146	303	2	,	,	,
cord-024061-gxv8y146	303	3	unlike	unlike	IN
cord-024061-gxv8y146	303	4	classical	classical	JJ
cord-024061-gxv8y146	303	5	phylogenetic	phylogenetic	JJ
cord-024061-gxv8y146	303	6	methods	method	NNS
cord-024061-gxv8y146	303	7	currently	currently	RB
cord-024061-gxv8y146	303	8	implemented	implement	VBN
cord-024061-gxv8y146	303	9	within	within	IN
cord-024061-gxv8y146	303	10	the	the	DT
cord-024061-gxv8y146	303	11	SI	SI	NNP
cord-024061-gxv8y146	303	12	surveillance	surveillance	NN
cord-024061-gxv8y146	303	13	system	system	NN
cord-024061-gxv8y146	303	14	in	in	IN
cord-024061-gxv8y146	303	15	the	the	DT
cord-024061-gxv8y146	303	16	United	United	NNP
cord-024061-gxv8y146	303	17	States	States	NNP
cord-024061-gxv8y146	303	18	,	,	,
cord-024061-gxv8y146	303	19	we	-PRON-	PRP
cord-024061-gxv8y146	303	20	were	be	VBD
cord-024061-gxv8y146	303	21	able	able	JJ
cord-024061-gxv8y146	303	22	to	to	TO
cord-024061-gxv8y146	303	23	reveal	reveal	VB
cord-024061-gxv8y146	303	24	higher	high	JJR
cord-024061-gxv8y146	303	25	resolution	resolution	NN
cord-024061-gxv8y146	303	26	insights	insight	NNS
cord-024061-gxv8y146	303	27	into	into	IN
cord-024061-gxv8y146	303	28	the	the	DT
cord-024061-gxv8y146	303	29	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	303	30	epidemiology	epidemiology	NN
cord-024061-gxv8y146	303	31	of	of	IN
cord-024061-gxv8y146	303	32	human	human	NN
cord-024061-gxv8y146	303	33	-	-	HYPH
cord-024061-gxv8y146	303	34	like	like	JJ
cord-024061-gxv8y146	303	35	H3	H3	NNP
cord-024061-gxv8y146	303	36	viruses	virus	NNS
cord-024061-gxv8y146	303	37	by	by	IN
cord-024061-gxv8y146	303	38	quantifying	quantify	VBG
cord-024061-gxv8y146	303	39	their	-PRON-	PRP$
cord-024061-gxv8y146	303	40	demographic	demographic	JJ
cord-024061-gxv8y146	303	41	and	and	CC
cord-024061-gxv8y146	303	42	phylogeographic	phylogeographic	JJ
cord-024061-gxv8y146	303	43	history	history	NN
cord-024061-gxv8y146	303	44	.	.	.
cord-024061-gxv8y146	304	1	Therefore	therefore	RB
cord-024061-gxv8y146	304	2	,	,	,
cord-024061-gxv8y146	304	3	animal	animal	NN
cord-024061-gxv8y146	304	4	health	health	NN
cord-024061-gxv8y146	304	5	researchers	researcher	NNS
cord-024061-gxv8y146	304	6	and	and	CC
cord-024061-gxv8y146	304	7	stakeholders	stakeholder	NNS
cord-024061-gxv8y146	304	8	need	need	VBP
cord-024061-gxv8y146	304	9	to	to	TO
cord-024061-gxv8y146	304	10	be	be	VB
cord-024061-gxv8y146	304	11	aware	aware	JJ
cord-024061-gxv8y146	304	12	of	of	IN
cord-024061-gxv8y146	304	13	the	the	DT
cord-024061-gxv8y146	304	14	method	method	NN
cord-024061-gxv8y146	304	15	's	's	POS
cord-024061-gxv8y146	304	16	features	feature	NNS
cord-024061-gxv8y146	304	17	,	,	,
cord-024061-gxv8y146	304	18	strengths	strength	NNS
cord-024061-gxv8y146	304	19	,	,	,
cord-024061-gxv8y146	304	20	and	and	CC
cord-024061-gxv8y146	304	21	limitations	limitation	NNS
cord-024061-gxv8y146	304	22	for	for	IN
cord-024061-gxv8y146	304	23	generating	generate	VBG
cord-024061-gxv8y146	304	24	reliable	reliable	JJ
cord-024061-gxv8y146	304	25	inference	inference	NN
cord-024061-gxv8y146	304	26	to	to	TO
cord-024061-gxv8y146	304	27	guide	guide	VB
cord-024061-gxv8y146	304	28	future	future	JJ
cord-024061-gxv8y146	304	29	disease	disease	NN
cord-024061-gxv8y146	304	30	intervention	intervention	NN
cord-024061-gxv8y146	304	31	activities	activity	NNS
cord-024061-gxv8y146	304	32	properly	properly	RB
cord-024061-gxv8y146	304	33	.	.	.
cord-024061-gxv8y146	305	1	Epidemiology	epidemiology	NN
cord-024061-gxv8y146	305	2	of	of	IN
cord-024061-gxv8y146	305	3	Swine	Swine	NNP
cord-024061-gxv8y146	305	4	Influenza	Influenza	NNP
cord-024061-gxv8y146	305	5	in	in	IN
cord-024061-gxv8y146	305	6	the	the	DT
cord-024061-gxv8y146	305	7	U.S.	U.S.	NNP
cord-024061-gxv8y146	306	1	Based	base	VBN
cord-024061-gxv8y146	306	2	on	on	IN
cord-024061-gxv8y146	306	3	the	the	DT
cord-024061-gxv8y146	306	4	results	result	NNS
cord-024061-gxv8y146	306	5	of	of	IN
cord-024061-gxv8y146	306	6	the	the	DT
cord-024061-gxv8y146	306	7	best	good	JJS
cord-024061-gxv8y146	306	8	fitting	fitting	JJ
cord-024061-gxv8y146	306	9	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	306	10	models	model	NNS
cord-024061-gxv8y146	306	11	for	for	IN
cord-024061-gxv8y146	306	12	both	both	CC
cord-024061-gxv8y146	306	13	HA	HA	NNP
cord-024061-gxv8y146	306	14	and	and	CC
cord-024061-gxv8y146	306	15	PB2	PB2	NNP
cord-024061-gxv8y146	306	16	segments	segment	NNS
cord-024061-gxv8y146	306	17	,	,	,
cord-024061-gxv8y146	306	18	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	306	19	rates	rate	NNS
cord-024061-gxv8y146	306	20	of	of	IN
cord-024061-gxv8y146	306	21	currently	currently	RB
cord-024061-gxv8y146	306	22	circulating	circulate	VBG
cord-024061-gxv8y146	306	23	human	human	JJ
cord-024061-gxv8y146	306	24	-	-	HYPH
cord-024061-gxv8y146	306	25	like	like	JJ
cord-024061-gxv8y146	306	26	H3	H3	NNP
cord-024061-gxv8y146	306	27	viruses	virus	NNS
cord-024061-gxv8y146	306	28	in	in	IN
cord-024061-gxv8y146	306	29	the	the	DT
cord-024061-gxv8y146	306	30	United	United	NNP
cord-024061-gxv8y146	306	31	States	States	NNP
cord-024061-gxv8y146	306	32	remain	remain	VBP
cord-024061-gxv8y146	306	33	high	high	JJ
cord-024061-gxv8y146	306	34	with	with	IN
cord-024061-gxv8y146	306	35	no	no	DT
cord-024061-gxv8y146	306	36	apparent	apparent	JJ
cord-024061-gxv8y146	306	37	signs	sign	NNS
cord-024061-gxv8y146	306	38	of	of	IN
cord-024061-gxv8y146	306	39	substantial	substantial	JJ
cord-024061-gxv8y146	306	40	declines	decline	NNS
cord-024061-gxv8y146	306	41	(	(	-LRB-
cord-024061-gxv8y146	306	42	Figures	figure	NNS
cord-024061-gxv8y146	306	43	2B	2b	CD
cord-024061-gxv8y146	306	44	,	,	,
cord-024061-gxv8y146	306	45	D	D	NNP
cord-024061-gxv8y146	306	46	)	)	-RRB-
cord-024061-gxv8y146	306	47	and	and	CC
cord-024061-gxv8y146	306	48	were	be	VBD
cord-024061-gxv8y146	306	49	similar	similar	JJ
cord-024061-gxv8y146	306	50	to	to	IN
cord-024061-gxv8y146	306	51	what	what	WP
cord-024061-gxv8y146	306	52	was	be	VBD
cord-024061-gxv8y146	306	53	inferred	infer	VBN
cord-024061-gxv8y146	306	54	elsewhere	elsewhere	RB
cord-024061-gxv8y146	306	55	(	(	-LRB-
cord-024061-gxv8y146	306	56	117	117	CD
cord-024061-gxv8y146	306	57	)	)	-RRB-
cord-024061-gxv8y146	306	58	.	.	.
cord-024061-gxv8y146	307	1	Furthermore	furthermore	RB
cord-024061-gxv8y146	307	2	,	,	,
cord-024061-gxv8y146	307	3	inferred	infer	VBN
cord-024061-gxv8y146	307	4	relative	relative	JJ
cord-024061-gxv8y146	307	5	genetic	genetic	JJ
cord-024061-gxv8y146	307	6	diversity	diversity	NN
cord-024061-gxv8y146	307	7	through	through	IN
cord-024061-gxv8y146	307	8	time	time	NN
cord-024061-gxv8y146	307	9	did	do	VBD
cord-024061-gxv8y146	307	10	not	not	RB
cord-024061-gxv8y146	307	11	decline	decline	VB
cord-024061-gxv8y146	307	12	for	for	IN
cord-024061-gxv8y146	307	13	the	the	DT
cord-024061-gxv8y146	307	14	HA	HA	NNP
cord-024061-gxv8y146	307	15	segment	segment	NN
cord-024061-gxv8y146	307	16	and	and	CC
cord-024061-gxv8y146	307	17	showed	show	VBD
cord-024061-gxv8y146	307	18	evidence	evidence	NN
cord-024061-gxv8y146	307	19	of	of	IN
cord-024061-gxv8y146	307	20	seasonal	seasonal	JJ
cord-024061-gxv8y146	307	21	variation	variation	NN
cord-024061-gxv8y146	307	22	between	between	IN
cord-024061-gxv8y146	307	23	2014	2014	CD
cord-024061-gxv8y146	307	24	and	and	CC
cord-024061-gxv8y146	307	25	2018	2018	CD
cord-024061-gxv8y146	307	26	(	(	-LRB-
cord-024061-gxv8y146	307	27	Figures	figure	NNS
cord-024061-gxv8y146	307	28	4A	4a	CD
cord-024061-gxv8y146	307	29	,	,	,
cord-024061-gxv8y146	307	30	B	B	NNP
cord-024061-gxv8y146	307	31	)	)	-RRB-
cord-024061-gxv8y146	307	32	,	,	,
cord-024061-gxv8y146	307	33	while	while	IN
cord-024061-gxv8y146	307	34	a	a	DT
cord-024061-gxv8y146	307	35	slight	slight	JJ
cord-024061-gxv8y146	307	36	decline	decline	NN
cord-024061-gxv8y146	307	37	in	in	IN
cord-024061-gxv8y146	307	38	the	the	DT
cord-024061-gxv8y146	307	39	genetic	genetic	JJ
cord-024061-gxv8y146	307	40	diversity	diversity	NN
cord-024061-gxv8y146	307	41	was	be	VBD
cord-024061-gxv8y146	307	42	inferred	infer	VBN
cord-024061-gxv8y146	307	43	for	for	IN
cord-024061-gxv8y146	307	44	the	the	DT
cord-024061-gxv8y146	307	45	PB2	PB2	NNP
cord-024061-gxv8y146	307	46	segment	segment	NN
cord-024061-gxv8y146	307	47	between	between	IN
cord-024061-gxv8y146	307	48	2015	2015	CD
cord-024061-gxv8y146	307	49	and	and	CC
cord-024061-gxv8y146	307	50	2018	2018	CD
cord-024061-gxv8y146	307	51	(	(	-LRB-
cord-024061-gxv8y146	307	52	Figures	figure	NNS
cord-024061-gxv8y146	307	53	4C	4c	CD
cord-024061-gxv8y146	307	54	,	,	,
cord-024061-gxv8y146	307	55	D	D	NNP
cord-024061-gxv8y146	307	56	)	)	-RRB-
cord-024061-gxv8y146	307	57	.	.	.
cord-024061-gxv8y146	308	1	These	these	DT
cord-024061-gxv8y146	308	2	findings	finding	NNS
cord-024061-gxv8y146	308	3	suggest	suggest	VBP
cord-024061-gxv8y146	308	4	that	that	IN
cord-024061-gxv8y146	308	5	currently	currently	RB
cord-024061-gxv8y146	308	6	circulating	circulate	VBG
cord-024061-gxv8y146	308	7	human	human	JJ
cord-024061-gxv8y146	308	8	-	-	HYPH
cord-024061-gxv8y146	308	9	like	like	JJ
cord-024061-gxv8y146	308	10	H3	H3	NNP
cord-024061-gxv8y146	308	11	viruses	virus	NNS
cord-024061-gxv8y146	308	12	will	will	MD
cord-024061-gxv8y146	308	13	continue	continue	VB
cord-024061-gxv8y146	308	14	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	308	15	activity	activity	NN
cord-024061-gxv8y146	308	16	leading	lead	VBG
cord-024061-gxv8y146	308	17	to	to	IN
cord-024061-gxv8y146	308	18	the	the	DT
cord-024061-gxv8y146	308	19	generation	generation	NN
cord-024061-gxv8y146	308	20	of	of	IN
cord-024061-gxv8y146	308	21	novel	novel	JJ
cord-024061-gxv8y146	308	22	strains	strain	NNS
cord-024061-gxv8y146	308	23	,	,	,
cord-024061-gxv8y146	308	24	which	which	WDT
cord-024061-gxv8y146	308	25	is	be	VBZ
cord-024061-gxv8y146	308	26	attributed	attribute	VBN
cord-024061-gxv8y146	308	27	to	to	IN
cord-024061-gxv8y146	308	28	the	the	DT
cord-024061-gxv8y146	308	29	frequent	frequent	JJ
cord-024061-gxv8y146	308	30	and	and	CC
cord-024061-gxv8y146	308	31	continuous	continuous	JJ
cord-024061-gxv8y146	308	32	exchange	exchange	NN
cord-024061-gxv8y146	308	33	of	of	IN
cord-024061-gxv8y146	308	34	viruses	virus	NNS
cord-024061-gxv8y146	308	35	between	between	IN
cord-024061-gxv8y146	308	36	commercial	commercial	JJ
cord-024061-gxv8y146	308	37	and	and	CC
cord-024061-gxv8y146	308	38	exhibition	exhibition	NN
cord-024061-gxv8y146	308	39	swine	swine	NN
cord-024061-gxv8y146	308	40	operations	operation	NNS
cord-024061-gxv8y146	308	41	in	in	IN
cord-024061-gxv8y146	308	42	the	the	DT
cord-024061-gxv8y146	308	43	United	United	NNP
cord-024061-gxv8y146	308	44	States	States	NNP
cord-024061-gxv8y146	308	45	with	with	IN
cord-024061-gxv8y146	308	46	the	the	DT
cord-024061-gxv8y146	308	47	later	later	RB
cord-024061-gxv8y146	308	48	as	as	IN
cord-024061-gxv8y146	308	49	the	the	DT
cord-024061-gxv8y146	308	50	epicenter	epicenter	NN
cord-024061-gxv8y146	308	51	of	of	IN
cord-024061-gxv8y146	308	52	that	that	DT
cord-024061-gxv8y146	308	53	exchange	exchange	NN
cord-024061-gxv8y146	308	54	(	(	-LRB-
cord-024061-gxv8y146	308	55	117	117	CD
cord-024061-gxv8y146	308	56	)	)	-RRB-
cord-024061-gxv8y146	308	57	.	.	.
cord-024061-gxv8y146	309	1	Our	-PRON-	PRP$
cord-024061-gxv8y146	309	2	estimates	estimate	NNS
cord-024061-gxv8y146	309	3	of	of	IN
cord-024061-gxv8y146	309	4	the	the	DT
cord-024061-gxv8y146	309	5	TMRCAs	tmrca	NNS
cord-024061-gxv8y146	309	6	for	for	IN
cord-024061-gxv8y146	309	7	HA	HA	NNP
cord-024061-gxv8y146	309	8	segment	segment	NN
cord-024061-gxv8y146	309	9	slightly	slightly	RB
cord-024061-gxv8y146	309	10	agree	agree	VBP
cord-024061-gxv8y146	309	11	on	on	IN
cord-024061-gxv8y146	309	12	the	the	DT
cord-024061-gxv8y146	309	13	notion	notion	NN
cord-024061-gxv8y146	309	14	that	that	IN
cord-024061-gxv8y146	309	15	the	the	DT
cord-024061-gxv8y146	309	16	oldest	old	JJS
cord-024061-gxv8y146	309	17	H3	H3	NNP
cord-024061-gxv8y146	309	18	viruses	virus	NNS
cord-024061-gxv8y146	309	19	diverged	diverge	VBD
cord-024061-gxv8y146	309	20	from	from	IN
cord-024061-gxv8y146	309	21	earlier	early	JJR
cord-024061-gxv8y146	309	22	outbreaks	outbreak	NNS
cord-024061-gxv8y146	309	23	in	in	IN
cord-024061-gxv8y146	309	24	the	the	DT
cord-024061-gxv8y146	309	25	state	state	NN
cord-024061-gxv8y146	309	26	of	of	IN
cord-024061-gxv8y146	309	27	Minnesota	Minnesota	NNP
cord-024061-gxv8y146	309	28	,	,	,
cord-024061-gxv8y146	309	29	which	which	WDT
cord-024061-gxv8y146	309	30	is	be	VBZ
cord-024061-gxv8y146	309	31	a	a	DT
cord-024061-gxv8y146	309	32	central	central	JJ
cord-024061-gxv8y146	309	33	region	region	NN
cord-024061-gxv8y146	309	34	for	for	IN
cord-024061-gxv8y146	309	35	the	the	DT
cord-024061-gxv8y146	309	36	swine	swine	NN
cord-024061-gxv8y146	309	37	industry	industry	NN
cord-024061-gxv8y146	309	38	in	in	IN
cord-024061-gxv8y146	309	39	the	the	DT
cord-024061-gxv8y146	309	40	United	United	NNP
cord-024061-gxv8y146	309	41	States	States	NNP
cord-024061-gxv8y146	309	42	(	(	-LRB-
cord-024061-gxv8y146	309	43	Figure	Figure	NNP
cord-024061-gxv8y146	309	44	3	3	CD
cord-024061-gxv8y146	309	45	)	)	-RRB-
cord-024061-gxv8y146	309	46	.	.	.
cord-024061-gxv8y146	310	1	However	however	RB
cord-024061-gxv8y146	310	2	,	,	,
cord-024061-gxv8y146	310	3	the	the	DT
cord-024061-gxv8y146	310	4	notable	notable	JJ
cord-024061-gxv8y146	310	5	overlap	overlap	NN
cord-024061-gxv8y146	310	6	in	in	IN
cord-024061-gxv8y146	310	7	the	the	DT
cord-024061-gxv8y146	310	8	inferred	infer	VBN
cord-024061-gxv8y146	310	9	95	95	CD
cord-024061-gxv8y146	310	10	%	%	NN
cord-024061-gxv8y146	310	11	HPDs	hpd	NNS
cord-024061-gxv8y146	310	12	of	of	IN
cord-024061-gxv8y146	310	13	the	the	DT
cord-024061-gxv8y146	310	14	TMRCAs	tmrca	NNS
cord-024061-gxv8y146	310	15	between	between	IN
cord-024061-gxv8y146	310	16	most	most	JJS
cord-024061-gxv8y146	310	17	states	state	NNS
cord-024061-gxv8y146	310	18	(	(	-LRB-
cord-024061-gxv8y146	310	19	Figure	figure	NN
cord-024061-gxv8y146	310	20	3B	3b	CD
cord-024061-gxv8y146	310	21	)	)	-RRB-
cord-024061-gxv8y146	310	22	suggest	suggest	VBP
cord-024061-gxv8y146	310	23	that	that	IN
cord-024061-gxv8y146	310	24	the	the	DT
cord-024061-gxv8y146	310	25	currently	currently	RB
cord-024061-gxv8y146	310	26	circulating	circulate	VBG
cord-024061-gxv8y146	310	27	strains	strain	NNS
cord-024061-gxv8y146	310	28	are	be	VBP
cord-024061-gxv8y146	310	29	shifting	shift	VBG
cord-024061-gxv8y146	310	30	their	-PRON-	PRP$
cord-024061-gxv8y146	310	31	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	310	32	dynamics	dynamic	NNS
cord-024061-gxv8y146	310	33	in	in	IN
cord-024061-gxv8y146	310	34	terms	term	NNS
cord-024061-gxv8y146	310	35	of	of	IN
cord-024061-gxv8y146	310	36	re	re	NN
cord-024061-gxv8y146	310	37	-	-	NN
cord-024061-gxv8y146	310	38	emergence	emergence	NN
cord-024061-gxv8y146	310	39	and	and	CC
cord-024061-gxv8y146	310	40	dispersal	dispersal	NN
cord-024061-gxv8y146	310	41	when	when	WRB
cord-024061-gxv8y146	310	42	compared	compare	VBN
cord-024061-gxv8y146	310	43	to	to	IN
cord-024061-gxv8y146	310	44	earlier	early	JJR
cord-024061-gxv8y146	310	45	strains	strain	NNS
cord-024061-gxv8y146	310	46	.	.	.
cord-024061-gxv8y146	311	1	Additionally	additionally	RB
cord-024061-gxv8y146	311	2	,	,	,
cord-024061-gxv8y146	311	3	both	both	DT
cord-024061-gxv8y146	311	4	gene	gene	NN
cord-024061-gxv8y146	311	5	segments	segment	NNS
cord-024061-gxv8y146	311	6	agree	agree	VBP
cord-024061-gxv8y146	311	7	on	on	IN
cord-024061-gxv8y146	311	8	the	the	DT
cord-024061-gxv8y146	311	9	assumption	assumption	NN
cord-024061-gxv8y146	311	10	that	that	IN
cord-024061-gxv8y146	311	11	H3	H3	NNP
cord-024061-gxv8y146	311	12	outbreaks	outbreak	NNS
cord-024061-gxv8y146	311	13	were	be	VBD
cord-024061-gxv8y146	311	14	recently	recently	RB
cord-024061-gxv8y146	311	15	introduced	introduce	VBN
cord-024061-gxv8y146	311	16	into	into	IN
cord-024061-gxv8y146	311	17	the	the	DT
cord-024061-gxv8y146	311	18	state	state	NN
cord-024061-gxv8y146	311	19	of	of	IN
cord-024061-gxv8y146	311	20	Maryland	Maryland	NNP
cord-024061-gxv8y146	311	21	(	(	-LRB-
cord-024061-gxv8y146	311	22	Figure	Figure	NNP
cord-024061-gxv8y146	311	23	3	3	CD
cord-024061-gxv8y146	311	24	)	)	-RRB-
cord-024061-gxv8y146	311	25	.	.	.
cord-024061-gxv8y146	312	1	The	the	DT
cord-024061-gxv8y146	312	2	state	state	NN
cord-024061-gxv8y146	312	3	of	of	IN
cord-024061-gxv8y146	312	4	Minnesota	Minnesota	NNP
cord-024061-gxv8y146	312	5	was	be	VBD
cord-024061-gxv8y146	312	6	inferred	infer	VBN
cord-024061-gxv8y146	312	7	to	to	TO
cord-024061-gxv8y146	312	8	be	be	VB
cord-024061-gxv8y146	312	9	the	the	DT
cord-024061-gxv8y146	312	10	ancestral	ancestral	JJ
cord-024061-gxv8y146	312	11	location	location	NN
cord-024061-gxv8y146	312	12	of	of	IN
cord-024061-gxv8y146	312	13	human	human	NN
cord-024061-gxv8y146	312	14	-	-	HYPH
cord-024061-gxv8y146	312	15	like	like	JJ
cord-024061-gxv8y146	312	16	H3	H3	NNP
cord-024061-gxv8y146	312	17	viruses	virus	NNS
cord-024061-gxv8y146	312	18	isolated	isolate	VBN
cord-024061-gxv8y146	312	19	from	from	IN
cord-024061-gxv8y146	312	20	outbreaks	outbreak	NNS
cord-024061-gxv8y146	312	21	observed	observe	VBN
cord-024061-gxv8y146	312	22	between	between	IN
cord-024061-gxv8y146	312	23	2009	2009	CD
cord-024061-gxv8y146	312	24	and	and	CC
cord-024061-gxv8y146	312	25	2012	2012	CD
cord-024061-gxv8y146	312	26	(	(	-LRB-
cord-024061-gxv8y146	312	27	118	118	CD
cord-024061-gxv8y146	312	28	)	)	-RRB-
cord-024061-gxv8y146	312	29	,	,	,
cord-024061-gxv8y146	312	30	which	which	WDT
cord-024061-gxv8y146	312	31	agrees	agree	VBZ
cord-024061-gxv8y146	312	32	with	with	IN
cord-024061-gxv8y146	312	33	our	-PRON-	PRP$
cord-024061-gxv8y146	312	34	TMRCAs	tmrca	NNS
cord-024061-gxv8y146	312	35	inferred	infer	VBN
cord-024061-gxv8y146	312	36	from	from	IN
cord-024061-gxv8y146	312	37	HA	HA	NNP
cord-024061-gxv8y146	312	38	segment	segment	NN
cord-024061-gxv8y146	312	39	(	(	-LRB-
cord-024061-gxv8y146	312	40	Figure	figure	NN
cord-024061-gxv8y146	312	41	3	3	CD
cord-024061-gxv8y146	312	42	)	)	-RRB-
cord-024061-gxv8y146	312	43	.	.	.
cord-024061-gxv8y146	313	1	However	however	RB
cord-024061-gxv8y146	313	2	,	,	,
cord-024061-gxv8y146	313	3	results	result	NNS
cord-024061-gxv8y146	313	4	of	of	IN
cord-024061-gxv8y146	313	5	the	the	DT
cord-024061-gxv8y146	313	6	SG	SG	NNP
cord-024061-gxv8y146	313	7	+	+	CC
cord-024061-gxv8y146	313	8	UCLN	UCLN	NNP
cord-024061-gxv8y146	313	9	symmetric	symmetric	JJ
cord-024061-gxv8y146	313	10	model	model	NN
cord-024061-gxv8y146	313	11	,	,	,
cord-024061-gxv8y146	313	12	selected	select	VBN
cord-024061-gxv8y146	313	13	as	as	IN
cord-024061-gxv8y146	313	14	the	the	DT
cord-024061-gxv8y146	313	15	best	good	JJS
cord-024061-gxv8y146	313	16	fitting	fitting	JJ
cord-024061-gxv8y146	313	17	model	model	NN
cord-024061-gxv8y146	313	18	for	for	IN
cord-024061-gxv8y146	313	19	HA	HA	NNP
cord-024061-gxv8y146	313	20	sequence	sequence	NN
cord-024061-gxv8y146	313	21	data	datum	NNS
cord-024061-gxv8y146	313	22	(	(	-LRB-
cord-024061-gxv8y146	313	23	Supplementary	Supplementary	NNP
cord-024061-gxv8y146	313	24	Table	Table	NNP
cord-024061-gxv8y146	313	25	4	4	CD
cord-024061-gxv8y146	313	26	)	)	-RRB-
cord-024061-gxv8y146	313	27	,	,	,
cord-024061-gxv8y146	313	28	implicates	implicate	VBZ
cord-024061-gxv8y146	313	29	the	the	DT
cord-024061-gxv8y146	313	30	state	state	NN
cord-024061-gxv8y146	313	31	of	of	IN
cord-024061-gxv8y146	313	32	Iowa	Iowa	NNP
cord-024061-gxv8y146	313	33	as	as	IN
cord-024061-gxv8y146	313	34	the	the	DT
cord-024061-gxv8y146	313	35	ancestral	ancestral	JJ
cord-024061-gxv8y146	313	36	region	region	NN
cord-024061-gxv8y146	313	37	(	(	-LRB-
cord-024061-gxv8y146	313	38	after	after	IN
cord-024061-gxv8y146	313	39	2013	2013	CD
cord-024061-gxv8y146	313	40	)	)	-RRB-
cord-024061-gxv8y146	313	41	for	for	IN
cord-024061-gxv8y146	313	42	currently	currently	RB
cord-024061-gxv8y146	313	43	circulating	circulate	VBG
cord-024061-gxv8y146	313	44	human	human	NN
cord-024061-gxv8y146	313	45	-	-	HYPH
cord-024061-gxv8y146	313	46	like	like	JJ
cord-024061-gxv8y146	313	47	H3	H3	NNP
cord-024061-gxv8y146	313	48	viruses	virus	NNS
cord-024061-gxv8y146	313	49	,	,	,
cord-024061-gxv8y146	313	50	followed	follow	VBN
cord-024061-gxv8y146	313	51	by	by	IN
cord-024061-gxv8y146	313	52	the	the	DT
cord-024061-gxv8y146	313	53	state	state	NN
cord-024061-gxv8y146	313	54	of	of	IN
cord-024061-gxv8y146	313	55	Minnesota	Minnesota	NNP
cord-024061-gxv8y146	313	56	as	as	IN
cord-024061-gxv8y146	313	57	a	a	DT
cord-024061-gxv8y146	313	58	secondary	secondary	JJ
cord-024061-gxv8y146	313	59	ancestral	ancestral	JJ
cord-024061-gxv8y146	313	60	location	location	NN
cord-024061-gxv8y146	313	61	(	(	-LRB-
cord-024061-gxv8y146	313	62	Figure	figure	NN
cord-024061-gxv8y146	313	63	5H	5h	NN
cord-024061-gxv8y146	313	64	)	)	-RRB-
cord-024061-gxv8y146	313	65	.	.	.
cord-024061-gxv8y146	314	1	This	this	DT
cord-024061-gxv8y146	314	2	is	be	VBZ
cord-024061-gxv8y146	314	3	not	not	RB
cord-024061-gxv8y146	314	4	surprising	surprising	JJ
cord-024061-gxv8y146	314	5	since	since	IN
cord-024061-gxv8y146	314	6	Iowa	Iowa	NNP
cord-024061-gxv8y146	314	7	and	and	CC
cord-024061-gxv8y146	314	8	Minnesota	Minnesota	NNP
cord-024061-gxv8y146	314	9	share	share	VBP
cord-024061-gxv8y146	314	10	the	the	DT
cord-024061-gxv8y146	314	11	most	most	RBS
cord-024061-gxv8y146	314	12	prominent	prominent	JJ
cord-024061-gxv8y146	314	13	swine	swine	NN
cord-024061-gxv8y146	314	14	production	production	NN
cord-024061-gxv8y146	314	15	system	system	NN
cord-024061-gxv8y146	314	16	in	in	IN
cord-024061-gxv8y146	314	17	the	the	DT
cord-024061-gxv8y146	314	18	United	United	NNP
cord-024061-gxv8y146	314	19	States	States	NNP
cord-024061-gxv8y146	314	20	with	with	IN
cord-024061-gxv8y146	314	21	the	the	DT
cord-024061-gxv8y146	314	22	highest	high	JJS
cord-024061-gxv8y146	314	23	swine	swine	NN
cord-024061-gxv8y146	314	24	density	density	NN
cord-024061-gxv8y146	314	25	,	,	,
cord-024061-gxv8y146	314	26	unrestricted	unrestricted	JJ
cord-024061-gxv8y146	314	27	and	and	CC
cord-024061-gxv8y146	314	28	intense	intense	JJ
cord-024061-gxv8y146	314	29	movement	movement	NN
cord-024061-gxv8y146	314	30	of	of	IN
cord-024061-gxv8y146	314	31	animals	animal	NNS
cord-024061-gxv8y146	314	32	between	between	IN
cord-024061-gxv8y146	314	33	states	state	NNS
cord-024061-gxv8y146	314	34	.	.	.
cord-024061-gxv8y146	315	1	Although	although	IN
cord-024061-gxv8y146	315	2	Iowa	Iowa	NNP
cord-024061-gxv8y146	315	3	and	and	CC
cord-024061-gxv8y146	315	4	Minnesota	Minnesota	NNP
cord-024061-gxv8y146	315	5	are	be	VBP
cord-024061-gxv8y146	315	6	the	the	DT
cord-024061-gxv8y146	315	7	original	original	JJ
cord-024061-gxv8y146	315	8	hotspots	hotspot	NNS
cord-024061-gxv8y146	315	9	of	of	IN
cord-024061-gxv8y146	315	10	H3	H3	NNP
cord-024061-gxv8y146	315	11	viruses	virus	NNS
cord-024061-gxv8y146	315	12	,	,	,
cord-024061-gxv8y146	315	13	our	-PRON-	PRP$
cord-024061-gxv8y146	315	14	BSSVS	BSSVS	NNP
cord-024061-gxv8y146	315	15	BF	BF	NNP
cord-024061-gxv8y146	315	16	results	result	NNS
cord-024061-gxv8y146	315	17	showed	show	VBD
cord-024061-gxv8y146	315	18	a	a	DT
cord-024061-gxv8y146	315	19	markedly	markedly	RB
cord-024061-gxv8y146	315	20	significant	significant	JJ
cord-024061-gxv8y146	315	21	viral	viral	JJ
cord-024061-gxv8y146	315	22	dispersal	dispersal	NN
cord-024061-gxv8y146	315	23	route	route	NN
cord-024061-gxv8y146	315	24	between	between	IN
cord-024061-gxv8y146	315	25	Indiana	Indiana	NNP
cord-024061-gxv8y146	315	26	and	and	CC
cord-024061-gxv8y146	315	27	Ohio	Ohio	NNP
cord-024061-gxv8y146	315	28	(	(	-LRB-
cord-024061-gxv8y146	315	29	BF	BF	NNP
cord-024061-gxv8y146	315	30	=	=	SYM
cord-024061-gxv8y146	315	31	990	990	CD
cord-024061-gxv8y146	315	32	)	)	-RRB-
cord-024061-gxv8y146	315	33	(	(	-LRB-
cord-024061-gxv8y146	315	34	Figure	figure	NN
cord-024061-gxv8y146	315	35	7H	7h	CD
cord-024061-gxv8y146	315	36	)	)	-RRB-
cord-024061-gxv8y146	315	37	.	.	.
cord-024061-gxv8y146	316	1	This	this	DT
cord-024061-gxv8y146	316	2	suggests	suggest	VBZ
cord-024061-gxv8y146	316	3	that	that	IN
cord-024061-gxv8y146	316	4	the	the	DT
cord-024061-gxv8y146	316	5	H3	H3	NNP
cord-024061-gxv8y146	316	6	viral	viral	JJ
cord-024061-gxv8y146	316	7	gene	gene	NN
cord-024061-gxv8y146	316	8	flow	flow	NN
cord-024061-gxv8y146	316	9	between	between	IN
cord-024061-gxv8y146	316	10	Ohio	Ohio	NNP
cord-024061-gxv8y146	316	11	and	and	CC
cord-024061-gxv8y146	316	12	Indiana	Indiana	NNP
cord-024061-gxv8y146	316	13	,	,	,
cord-024061-gxv8y146	316	14	inferred	infer	VBD
cord-024061-gxv8y146	316	15	for	for	IN
cord-024061-gxv8y146	316	16	2009	2009	CD
cord-024061-gxv8y146	316	17	-	-	SYM
cord-024061-gxv8y146	316	18	2012	2012	CD
cord-024061-gxv8y146	316	19	viruses	virus	NNS
cord-024061-gxv8y146	316	20	remains	remain	VBZ
cord-024061-gxv8y146	316	21	a	a	DT
cord-024061-gxv8y146	316	22	vital	vital	JJ
cord-024061-gxv8y146	316	23	migration	migration	NN
cord-024061-gxv8y146	316	24	route	route	NN
cord-024061-gxv8y146	316	25	since	since	IN
cord-024061-gxv8y146	316	26	,	,	,
cord-024061-gxv8y146	316	27	particularly	particularly	RB
cord-024061-gxv8y146	316	28	within	within	IN
cord-024061-gxv8y146	316	29	exhibition	exhibition	NN
cord-024061-gxv8y146	316	30	swine	swine	NN
cord-024061-gxv8y146	316	31	populations	population	NNS
cord-024061-gxv8y146	316	32	(	(	-LRB-
cord-024061-gxv8y146	316	33	117	117	CD
cord-024061-gxv8y146	316	34	)	)	-RRB-
cord-024061-gxv8y146	316	35	.	.	.
cord-024061-gxv8y146	317	1	Even	even	RB
cord-024061-gxv8y146	317	2	though	though	IN
cord-024061-gxv8y146	317	3	Illinois	Illinois	NNP
cord-024061-gxv8y146	317	4	and	and	CC
cord-024061-gxv8y146	317	5	Indiana	Indiana	NNP
cord-024061-gxv8y146	317	6	formulate	formulate	VB
cord-024061-gxv8y146	317	7	one	one	CD
cord-024061-gxv8y146	317	8	swine	swine	NN
cord-024061-gxv8y146	317	9	production	production	NN
cord-024061-gxv8y146	317	10	system	system	NN
cord-024061-gxv8y146	317	11	,	,	,
cord-024061-gxv8y146	317	12	there	there	EX
cord-024061-gxv8y146	317	13	was	be	VBD
cord-024061-gxv8y146	317	14	no	no	DT
cord-024061-gxv8y146	317	15	significant	significant	JJ
cord-024061-gxv8y146	317	16	viral	viral	JJ
cord-024061-gxv8y146	317	17	dispersal	dispersal	NN
cord-024061-gxv8y146	317	18	route	route	NN
cord-024061-gxv8y146	317	19	inferred	infer	VBN
cord-024061-gxv8y146	317	20	between	between	IN
cord-024061-gxv8y146	317	21	the	the	DT
cord-024061-gxv8y146	317	22	states	state	NNS
cord-024061-gxv8y146	317	23	.	.	.
cord-024061-gxv8y146	318	1	Despite	despite	IN
cord-024061-gxv8y146	318	2	the	the	DT
cord-024061-gxv8y146	318	3	continuous	continuous	JJ
cord-024061-gxv8y146	318	4	nature	nature	NN
cord-024061-gxv8y146	318	5	of	of	IN
cord-024061-gxv8y146	318	6	animal	animal	NN
cord-024061-gxv8y146	318	7	movement	movement	NN
cord-024061-gxv8y146	318	8	within	within	IN
cord-024061-gxv8y146	318	9	the	the	DT
cord-024061-gxv8y146	318	10	production	production	NN
cord-024061-gxv8y146	318	11	system	system	NN
cord-024061-gxv8y146	318	12	of	of	IN
cord-024061-gxv8y146	318	13	Minnesota	Minnesota	NNP
cord-024061-gxv8y146	318	14	and	and	CC
cord-024061-gxv8y146	318	15	Iowa	Iowa	NNP
cord-024061-gxv8y146	318	16	,	,	,
cord-024061-gxv8y146	318	17	no	no	DT
cord-024061-gxv8y146	318	18	significant	significant	JJ
cord-024061-gxv8y146	318	19	dispersal	dispersal	NN
cord-024061-gxv8y146	318	20	route	route	NN
cord-024061-gxv8y146	318	21	was	be	VBD
cord-024061-gxv8y146	318	22	inferred	infer	VBN
cord-024061-gxv8y146	318	23	between	between	IN
cord-024061-gxv8y146	318	24	the	the	DT
cord-024061-gxv8y146	318	25	two	two	CD
cord-024061-gxv8y146	318	26	states	state	NNS
cord-024061-gxv8y146	318	27	using	use	VBG
cord-024061-gxv8y146	318	28	the	the	DT
cord-024061-gxv8y146	318	29	HA	HA	NNP
cord-024061-gxv8y146	318	30	segment	segment	NN
cord-024061-gxv8y146	318	31	(	(	-LRB-
cord-024061-gxv8y146	318	32	Figure	figure	NN
cord-024061-gxv8y146	318	33	7H	7h	CD
cord-024061-gxv8y146	318	34	)	)	-RRB-
cord-024061-gxv8y146	318	35	.	.	.
cord-024061-gxv8y146	319	1	Nevertheless	nevertheless	RB
cord-024061-gxv8y146	319	2	,	,	,
cord-024061-gxv8y146	319	3	using	use	VBG
cord-024061-gxv8y146	319	4	the	the	DT
cord-024061-gxv8y146	319	5	PB2	PB2	NNP
cord-024061-gxv8y146	319	6	segment	segment	NN
cord-024061-gxv8y146	319	7	,	,	,
cord-024061-gxv8y146	319	8	a	a	DT
cord-024061-gxv8y146	319	9	highly	highly	RB
cord-024061-gxv8y146	319	10	significant	significant	JJ
cord-024061-gxv8y146	319	11	dispersal	dispersal	NN
cord-024061-gxv8y146	319	12	route	route	NN
cord-024061-gxv8y146	319	13	was	be	VBD
cord-024061-gxv8y146	319	14	inferred	infer	VBN
cord-024061-gxv8y146	319	15	from	from	IN
cord-024061-gxv8y146	319	16	Iowa	Iowa	NNP
cord-024061-gxv8y146	319	17	to	to	IN
cord-024061-gxv8y146	319	18	Minnesota	Minnesota	NNP
cord-024061-gxv8y146	319	19	,	,	,
cord-024061-gxv8y146	319	20	suggesting	suggest	VBG
cord-024061-gxv8y146	319	21	that	that	IN
cord-024061-gxv8y146	319	22	Iowa	Iowa	NNP
cord-024061-gxv8y146	319	23	might	may	MD
cord-024061-gxv8y146	319	24	be	be	VB
cord-024061-gxv8y146	319	25	the	the	DT
cord-024061-gxv8y146	319	26	new	new	JJ
cord-024061-gxv8y146	319	27	epicenter	epicenter	NN
cord-024061-gxv8y146	319	28	for	for	IN
cord-024061-gxv8y146	319	29	virus	virus	NN
cord-024061-gxv8y146	319	30	dispersal	dispersal	NN
cord-024061-gxv8y146	319	31	of	of	IN
cord-024061-gxv8y146	319	32	the	the	DT
cord-024061-gxv8y146	319	33	currently	currently	RB
cord-024061-gxv8y146	319	34	circulating	circulate	VBG
cord-024061-gxv8y146	319	35	H3	H3	NNP
cord-024061-gxv8y146	319	36	lineages	lineage	NNS
cord-024061-gxv8y146	319	37	(	(	-LRB-
cord-024061-gxv8y146	319	38	Figure	figure	NN
cord-024061-gxv8y146	319	39	8D	8d	NN
cord-024061-gxv8y146	319	40	)	)	-RRB-
cord-024061-gxv8y146	319	41	.	.	.
cord-024061-gxv8y146	320	1	This	this	DT
cord-024061-gxv8y146	320	2	result	result	NN
cord-024061-gxv8y146	320	3	is	be	VBZ
cord-024061-gxv8y146	320	4	further	further	RB
cord-024061-gxv8y146	320	5	supported	support	VBN
cord-024061-gxv8y146	320	6	by	by	IN
cord-024061-gxv8y146	320	7	the	the	DT
cord-024061-gxv8y146	320	8	significant	significant	JJ
cord-024061-gxv8y146	320	9	migration	migration	NN
cord-024061-gxv8y146	320	10	route	route	NN
cord-024061-gxv8y146	320	11	between	between	IN
cord-024061-gxv8y146	320	12	Iowa	Iowa	NNP
cord-024061-gxv8y146	320	13	on	on	IN
cord-024061-gxv8y146	320	14	one	one	CD
cord-024061-gxv8y146	320	15	side	side	NN
cord-024061-gxv8y146	320	16	and	and	CC
cord-024061-gxv8y146	320	17	Illinois	Illinois	NNP
cord-024061-gxv8y146	320	18	and	and	CC
cord-024061-gxv8y146	320	19	Ohio	Ohio	NNP
cord-024061-gxv8y146	320	20	on	on	IN
cord-024061-gxv8y146	320	21	the	the	DT
cord-024061-gxv8y146	320	22	other	other	JJ
cord-024061-gxv8y146	320	23	when	when	WRB
cord-024061-gxv8y146	320	24	using	use	VBG
cord-024061-gxv8y146	320	25	the	the	DT
cord-024061-gxv8y146	320	26	HA	HA	NNP
cord-024061-gxv8y146	320	27	segment	segment	NN
cord-024061-gxv8y146	320	28	(	(	-LRB-
cord-024061-gxv8y146	320	29	Figure	figure	NN
cord-024061-gxv8y146	320	30	7H	7h	CD
cord-024061-gxv8y146	320	31	)	)	-RRB-
cord-024061-gxv8y146	320	32	.	.	.
cord-024061-gxv8y146	321	1	Also	also	RB
cord-024061-gxv8y146	321	2	,	,	,
cord-024061-gxv8y146	321	3	the	the	DT
cord-024061-gxv8y146	321	4	inferred	infer	VBN
cord-024061-gxv8y146	321	5	dispersal	dispersal	NN
cord-024061-gxv8y146	321	6	route	route	NN
cord-024061-gxv8y146	321	7	between	between	IN
cord-024061-gxv8y146	321	8	Iowa	Iowa	NNP
cord-024061-gxv8y146	321	9	and	and	CC
cord-024061-gxv8y146	321	10	Illinois	Illinois	NNP
cord-024061-gxv8y146	321	11	(	(	-LRB-
cord-024061-gxv8y146	321	12	Figure	Figure	NNP
cord-024061-gxv8y146	321	13	7H	7h	CD
cord-024061-gxv8y146	321	14	)	)	-RRB-
cord-024061-gxv8y146	321	15	may	may	MD
cord-024061-gxv8y146	321	16	reflect	reflect	VB
cord-024061-gxv8y146	321	17	interstate	interstate	JJ
cord-024061-gxv8y146	321	18	movements	movement	NNS
cord-024061-gxv8y146	321	19	of	of	IN
cord-024061-gxv8y146	321	20	exhibition	exhibition	NN
cord-024061-gxv8y146	321	21	pigs	pig	NNS
cord-024061-gxv8y146	321	22	(	(	-LRB-
cord-024061-gxv8y146	321	23	119	119	CD
cord-024061-gxv8y146	321	24	)	)	-RRB-
cord-024061-gxv8y146	321	25	.	.	.
cord-024061-gxv8y146	322	1	Hence	hence	RB
cord-024061-gxv8y146	322	2	,	,	,
cord-024061-gxv8y146	322	3	the	the	DT
cord-024061-gxv8y146	322	4	movements	movement	NNS
cord-024061-gxv8y146	322	5	of	of	IN
cord-024061-gxv8y146	322	6	exhibition	exhibition	NN
cord-024061-gxv8y146	322	7	pigs	pig	NNS
cord-024061-gxv8y146	322	8	across	across	IN
cord-024061-gxv8y146	322	9	the	the	DT
cord-024061-gxv8y146	322	10	United	United	NNP
cord-024061-gxv8y146	322	11	States	States	NNP
cord-024061-gxv8y146	322	12	possibly	possibly	RB
cord-024061-gxv8y146	322	13	led	lead	VBD
cord-024061-gxv8y146	322	14	to	to	IN
cord-024061-gxv8y146	322	15	expanding	expand	VBG
cord-024061-gxv8y146	322	16	the	the	DT
cord-024061-gxv8y146	322	17	spatial	spatial	JJ
cord-024061-gxv8y146	322	18	spread	spread	NN
cord-024061-gxv8y146	322	19	of	of	IN
cord-024061-gxv8y146	322	20	H3	H3	NNP
cord-024061-gxv8y146	322	21	viruses	virus	NNS
cord-024061-gxv8y146	322	22	to	to	IN
cord-024061-gxv8y146	322	23	states	state	NNS
cord-024061-gxv8y146	322	24	with	with	IN
cord-024061-gxv8y146	322	25	limited	limited	JJ
cord-024061-gxv8y146	322	26	swine	swine	NN
cord-024061-gxv8y146	322	27	production	production	NN
cord-024061-gxv8y146	322	28	systems	system	NNS
cord-024061-gxv8y146	322	29	(	(	-LRB-
cord-024061-gxv8y146	322	30	117	117	CD
cord-024061-gxv8y146	322	31	)	)	-RRB-
cord-024061-gxv8y146	322	32	.	.	.
cord-024061-gxv8y146	323	1	Unlike	unlike	IN
cord-024061-gxv8y146	323	2	the	the	DT
cord-024061-gxv8y146	323	3	HA	HA	NNP
cord-024061-gxv8y146	323	4	segment	segment	NN
cord-024061-gxv8y146	323	5	,	,	,
cord-024061-gxv8y146	323	6	RSPPs	rspp	NNS
cord-024061-gxv8y146	323	7	inferred	infer	VBN
cord-024061-gxv8y146	323	8	from	from	IN
cord-024061-gxv8y146	323	9	the	the	DT
cord-024061-gxv8y146	323	10	most	most	RBS
cord-024061-gxv8y146	323	11	realistic	realistic	JJ
cord-024061-gxv8y146	323	12	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	323	13	model	model	NN
cord-024061-gxv8y146	323	14	for	for	IN
cord-024061-gxv8y146	323	15	PB2	PB2	NNP
cord-024061-gxv8y146	323	16	sequences	sequence	NNS
cord-024061-gxv8y146	323	17	(	(	-LRB-
cord-024061-gxv8y146	323	18	i.e.	i.e.	FW
cord-024061-gxv8y146	323	19	,	,	,
cord-024061-gxv8y146	323	20	asymmetric	asymmetric	JJ
cord-024061-gxv8y146	323	21	+	+	CC
cord-024061-gxv8y146	323	22	SG	sg	NN
cord-024061-gxv8y146	323	23	+	+	CC
cord-024061-gxv8y146	323	24	UCED	UCED	NNP
cord-024061-gxv8y146	323	25	)	)	-RRB-
cord-024061-gxv8y146	323	26	(	(	-LRB-
cord-024061-gxv8y146	323	27	Supplementary	Supplementary	NNP
cord-024061-gxv8y146	323	28	Table	Table	NNP
cord-024061-gxv8y146	323	29	5	5	CD
cord-024061-gxv8y146	323	30	)	)	-RRB-
cord-024061-gxv8y146	323	31	did	do	VBD
cord-024061-gxv8y146	323	32	not	not	RB
cord-024061-gxv8y146	323	33	yield	yield	VB
cord-024061-gxv8y146	323	34	conclusive	conclusive	JJ
cord-024061-gxv8y146	323	35	results	result	NNS
cord-024061-gxv8y146	323	36	about	about	IN
cord-024061-gxv8y146	323	37	the	the	DT
cord-024061-gxv8y146	323	38	ancestral	ancestral	JJ
cord-024061-gxv8y146	323	39	geographical	geographical	JJ
cord-024061-gxv8y146	323	40	origin	origin	NN
cord-024061-gxv8y146	323	41	of	of	IN
cord-024061-gxv8y146	323	42	human	human	NN
cord-024061-gxv8y146	323	43	-	-	HYPH
cord-024061-gxv8y146	323	44	like	like	JJ
cord-024061-gxv8y146	323	45	H3	H3	NNP
cord-024061-gxv8y146	323	46	in	in	IN
cord-024061-gxv8y146	323	47	the	the	DT
cord-024061-gxv8y146	323	48	United	United	NNP
cord-024061-gxv8y146	323	49	States	States	NNP
cord-024061-gxv8y146	323	50	(	(	-LRB-
cord-024061-gxv8y146	323	51	Figure	Figure	NNP
cord-024061-gxv8y146	323	52	6D	6D	NNP
cord-024061-gxv8y146	323	53	)	)	-RRB-
cord-024061-gxv8y146	323	54	.	.	.
cord-024061-gxv8y146	324	1	Instead	instead	RB
cord-024061-gxv8y146	324	2	,	,	,
cord-024061-gxv8y146	324	3	this	this	DT
cord-024061-gxv8y146	324	4	result	result	NN
cord-024061-gxv8y146	324	5	demonstrates	demonstrate	VBZ
cord-024061-gxv8y146	324	6	a	a	DT
cord-024061-gxv8y146	324	7	homogenous	homogenous	JJ
cord-024061-gxv8y146	324	8	spatio	spatio	JJ
cord-024061-gxv8y146	324	9	-	-	HYPH
cord-024061-gxv8y146	324	10	temporal	temporal	JJ
cord-024061-gxv8y146	324	11	diffusion	diffusion	NN
cord-024061-gxv8y146	324	12	process	process	NN
cord-024061-gxv8y146	324	13	of	of	IN
cord-024061-gxv8y146	324	14	the	the	DT
cord-024061-gxv8y146	324	15	PB2	PB2	NNP
cord-024061-gxv8y146	324	16	gene	gene	NN
cord-024061-gxv8y146	324	17	between	between	IN
cord-024061-gxv8y146	324	18	states	state	NNS
cord-024061-gxv8y146	324	19	(	(	-LRB-
cord-024061-gxv8y146	324	20	Figure	Figure	NNP
cord-024061-gxv8y146	324	21	6D	6D	NNP
cord-024061-gxv8y146	324	22	)	)	-RRB-
cord-024061-gxv8y146	324	23	,	,	,
cord-024061-gxv8y146	324	24	suggesting	suggest	VBG
cord-024061-gxv8y146	324	25	that	that	IN
cord-024061-gxv8y146	324	26	the	the	DT
cord-024061-gxv8y146	324	27	virus	virus	NN
cord-024061-gxv8y146	324	28	has	have	VBZ
cord-024061-gxv8y146	324	29	maintained	maintain	VBN
cord-024061-gxv8y146	324	30	an	an	DT
cord-024061-gxv8y146	324	31	endemic	endemic	JJ
cord-024061-gxv8y146	324	32	status	status	NN
cord-024061-gxv8y146	324	33	across	across	IN
cord-024061-gxv8y146	324	34	the	the	DT
cord-024061-gxv8y146	324	35	United	United	NNP
cord-024061-gxv8y146	324	36	States	States	NNP
cord-024061-gxv8y146	324	37	after	after	IN
cord-024061-gxv8y146	324	38	2010	2010	CD
cord-024061-gxv8y146	324	39	.	.	.
cord-024061-gxv8y146	325	1	Also	also	RB
cord-024061-gxv8y146	325	2	,	,	,
cord-024061-gxv8y146	325	3	results	result	NNS
cord-024061-gxv8y146	325	4	of	of	IN
cord-024061-gxv8y146	325	5	the	the	DT
cord-024061-gxv8y146	325	6	SG	SG	NNP
cord-024061-gxv8y146	325	7	plot	plot	NN
cord-024061-gxv8y146	325	8	for	for	IN
cord-024061-gxv8y146	325	9	PB2	PB2	NNP
cord-024061-gxv8y146	325	10	,	,	,
cord-024061-gxv8y146	325	11	described	describe	VBN
cord-024061-gxv8y146	325	12	above	above	RB
cord-024061-gxv8y146	325	13	,	,	,
cord-024061-gxv8y146	325	14	showed	show	VBD
cord-024061-gxv8y146	325	15	an	an	DT
cord-024061-gxv8y146	325	16	overall	overall	JJ
cord-024061-gxv8y146	325	17	stationarity	stationarity	NN
cord-024061-gxv8y146	325	18	in	in	IN
cord-024061-gxv8y146	325	19	its	-PRON-	PRP$
cord-024061-gxv8y146	325	20	genetic	genetic	JJ
cord-024061-gxv8y146	325	21	diversity	diversity	NN
cord-024061-gxv8y146	325	22	through	through	IN
cord-024061-gxv8y146	325	23	time	time	NN
cord-024061-gxv8y146	325	24	(	(	-LRB-
cord-024061-gxv8y146	325	25	despite	despite	IN
cord-024061-gxv8y146	325	26	the	the	DT
cord-024061-gxv8y146	325	27	slight	slight	JJ
cord-024061-gxv8y146	325	28	early	early	JJ
cord-024061-gxv8y146	325	29	incline	incline	NN
cord-024061-gxv8y146	325	30	and	and	CC
cord-024061-gxv8y146	325	31	later	later	RB
cord-024061-gxv8y146	325	32	decline	decline	VB
cord-024061-gxv8y146	325	33	)	)	-RRB-
cord-024061-gxv8y146	326	1	(	(	-LRB-
cord-024061-gxv8y146	326	2	Figure	figure	NN
cord-024061-gxv8y146	326	3	4C	4c	CD
cord-024061-gxv8y146	326	4	)	)	-RRB-
cord-024061-gxv8y146	326	5	,	,	,
cord-024061-gxv8y146	326	6	when	when	WRB
cord-024061-gxv8y146	326	7	compared	compare	VBN
cord-024061-gxv8y146	326	8	to	to	IN
cord-024061-gxv8y146	326	9	the	the	DT
cord-024061-gxv8y146	326	10	HA	HA	NNP
cord-024061-gxv8y146	326	11	gene	gene	NN
cord-024061-gxv8y146	326	12	(	(	-LRB-
cord-024061-gxv8y146	326	13	Figures	figure	NNS
cord-024061-gxv8y146	326	14	4A	4a	CD
cord-024061-gxv8y146	326	15	,	,	,
cord-024061-gxv8y146	326	16	B	B	NNP
cord-024061-gxv8y146	326	17	)	)	-RRB-
cord-024061-gxv8y146	326	18	,	,	,
cord-024061-gxv8y146	326	19	supporting	support	VBG
cord-024061-gxv8y146	326	20	the	the	DT
cord-024061-gxv8y146	326	21	notion	notion	NN
cord-024061-gxv8y146	326	22	of	of	IN
cord-024061-gxv8y146	326	23	endemic	endemic	JJ
cord-024061-gxv8y146	326	24	status	status	NN
cord-024061-gxv8y146	326	25	.	.	.
cord-024061-gxv8y146	327	1	However	however	RB
cord-024061-gxv8y146	327	2	,	,	,
cord-024061-gxv8y146	327	3	using	use	VBG
cord-024061-gxv8y146	327	4	the	the	DT
cord-024061-gxv8y146	327	5	PB2	PB2	NNP
cord-024061-gxv8y146	327	6	segment	segment	NN
cord-024061-gxv8y146	327	7	,	,	,
cord-024061-gxv8y146	327	8	we	-PRON-	PRP
cord-024061-gxv8y146	327	9	inferred	infer	VBD
cord-024061-gxv8y146	327	10	a	a	DT
cord-024061-gxv8y146	327	11	notably	notably	RB
cord-024061-gxv8y146	327	12	significant	significant	JJ
cord-024061-gxv8y146	327	13	dispersal	dispersal	NN
cord-024061-gxv8y146	327	14	route	route	NN
cord-024061-gxv8y146	327	15	originating	originate	VBG
cord-024061-gxv8y146	327	16	from	from	IN
cord-024061-gxv8y146	327	17	Iowa	Iowa	NNP
cord-024061-gxv8y146	327	18	to	to	IN
cord-024061-gxv8y146	327	19	Minnesota	Minnesota	NNP
cord-024061-gxv8y146	328	1	(	(	-LRB-
cord-024061-gxv8y146	328	2	BSSVS	BSSVS	NNP
cord-024061-gxv8y146	328	3	=	=	SYM
cord-024061-gxv8y146	328	4	193	193	CD
cord-024061-gxv8y146	328	5	)	)	-RRB-
cord-024061-gxv8y146	328	6	(	(	-LRB-
cord-024061-gxv8y146	328	7	Figure	figure	NN
cord-024061-gxv8y146	328	8	8D	8d	NN
cord-024061-gxv8y146	328	9	)	)	-RRB-
cord-024061-gxv8y146	328	10	,	,	,
cord-024061-gxv8y146	328	11	reflecting	reflect	VBG
cord-024061-gxv8y146	328	12	a	a	DT
cord-024061-gxv8y146	328	13	well	well	RB
cord-024061-gxv8y146	328	14	-	-	HYPH
cord-024061-gxv8y146	328	15	established	establish	VBN
cord-024061-gxv8y146	328	16	swine	swine	NN
cord-024061-gxv8y146	328	17	transportation	transportation	NN
cord-024061-gxv8y146	328	18	route	route	NN
cord-024061-gxv8y146	328	19	within	within	IN
cord-024061-gxv8y146	328	20	a	a	DT
cord-024061-gxv8y146	328	21	production	production	NN
cord-024061-gxv8y146	328	22	system	system	NN
cord-024061-gxv8y146	328	23	,	,	,
cord-024061-gxv8y146	328	24	as	as	IN
cord-024061-gxv8y146	328	25	described	describe	VBN
cord-024061-gxv8y146	328	26	above	above	RB
cord-024061-gxv8y146	328	27	.	.	.
cord-024061-gxv8y146	329	1	However	however	RB
cord-024061-gxv8y146	329	2	,	,	,
cord-024061-gxv8y146	329	3	this	this	DT
cord-024061-gxv8y146	329	4	route	route	NN
cord-024061-gxv8y146	329	5	was	be	VBD
cord-024061-gxv8y146	329	6	not	not	RB
cord-024061-gxv8y146	329	7	inferred	infer	VBN
cord-024061-gxv8y146	329	8	as	as	IN
cord-024061-gxv8y146	329	9	significant	significant	JJ
cord-024061-gxv8y146	329	10	when	when	WRB
cord-024061-gxv8y146	329	11	using	use	VBG
cord-024061-gxv8y146	329	12	the	the	DT
cord-024061-gxv8y146	329	13	best	good	JJS
cord-024061-gxv8y146	329	14	fitting	fitting	JJ
cord-024061-gxv8y146	329	15	model	model	NN
cord-024061-gxv8y146	329	16	for	for	IN
cord-024061-gxv8y146	329	17	the	the	DT
cord-024061-gxv8y146	329	18	HA	HA	NNP
cord-024061-gxv8y146	329	19	segment	segment	NN
cord-024061-gxv8y146	329	20	(	(	-LRB-
cord-024061-gxv8y146	329	21	Figure	figure	NN
cord-024061-gxv8y146	329	22	7H	7h	CD
cord-024061-gxv8y146	329	23	)	)	-RRB-
cord-024061-gxv8y146	329	24	.	.	.
cord-024061-gxv8y146	330	1	These	these	DT
cord-024061-gxv8y146	330	2	results	result	NNS
cord-024061-gxv8y146	330	3	may	may	MD
cord-024061-gxv8y146	330	4	be	be	VB
cord-024061-gxv8y146	330	5	attributed	attribute	VBN
cord-024061-gxv8y146	330	6	to	to	IN
cord-024061-gxv8y146	330	7	the	the	DT
cord-024061-gxv8y146	330	8	fact	fact	NN
cord-024061-gxv8y146	330	9	that	that	IN
cord-024061-gxv8y146	330	10	PB2	PB2	NNP
cord-024061-gxv8y146	330	11	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	330	12	dynamics	dynamic	NNS
cord-024061-gxv8y146	330	13	are	be	VBP
cord-024061-gxv8y146	330	14	moderately	moderately	RB
cord-024061-gxv8y146	330	15	slower	slow	JJR
cord-024061-gxv8y146	330	16	than	than	IN
cord-024061-gxv8y146	330	17	the	the	DT
cord-024061-gxv8y146	330	18	HA	HA	NNP
cord-024061-gxv8y146	330	19	segment	segment	NN
cord-024061-gxv8y146	330	20	(	(	-LRB-
cord-024061-gxv8y146	330	21	Figure	figure	NN
cord-024061-gxv8y146	330	22	2	2	CD
cord-024061-gxv8y146	330	23	)	)	-RRB-
cord-024061-gxv8y146	330	24	in	in	IN
cord-024061-gxv8y146	330	25	terms	term	NNS
cord-024061-gxv8y146	330	26	of	of	IN
cord-024061-gxv8y146	330	27	strength	strength	NN
cord-024061-gxv8y146	330	28	of	of	IN
cord-024061-gxv8y146	330	29	the	the	DT
cord-024061-gxv8y146	330	30	temporal	temporal	JJ
cord-024061-gxv8y146	330	31	signal	signal	NN
cord-024061-gxv8y146	330	32	(	(	-LRB-
cord-024061-gxv8y146	330	33	Supplementary	Supplementary	NNP
cord-024061-gxv8y146	330	34	Figure	Figure	NNP
cord-024061-gxv8y146	330	35	2	2	CD
cord-024061-gxv8y146	330	36	)	)	-RRB-
cord-024061-gxv8y146	330	37	,	,	,
cord-024061-gxv8y146	330	38	substitution	substitution	NN
cord-024061-gxv8y146	330	39	rate	rate	NN
cord-024061-gxv8y146	330	40	(	(	-LRB-
cord-024061-gxv8y146	330	41	Figure	figure	NN
cord-024061-gxv8y146	330	42	2	2	CD
cord-024061-gxv8y146	330	43	)	)	-RRB-
cord-024061-gxv8y146	330	44	,	,	,
cord-024061-gxv8y146	330	45	and	and	CC
cord-024061-gxv8y146	330	46	age	age	NN
cord-024061-gxv8y146	330	47	of	of	IN
cord-024061-gxv8y146	330	48	the	the	DT
cord-024061-gxv8y146	330	49	segment	segment	NN
cord-024061-gxv8y146	330	50	(	(	-LRB-
cord-024061-gxv8y146	330	51	Figure	figure	NN
cord-024061-gxv8y146	330	52	3	3	CD
cord-024061-gxv8y146	330	53	)	)	-RRB-
cord-024061-gxv8y146	330	54	.	.	.
cord-024061-gxv8y146	331	1	Therefore	therefore	RB
cord-024061-gxv8y146	331	2	,	,	,
cord-024061-gxv8y146	331	3	the	the	DT
cord-024061-gxv8y146	331	4	PB2	PB2	NNP
cord-024061-gxv8y146	331	5	segment	segment	NN
cord-024061-gxv8y146	331	6	maintained	maintain	VBD
cord-024061-gxv8y146	331	7	similar	similar	JJ
cord-024061-gxv8y146	331	8	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	331	9	dynamics	dynamic	NNS
cord-024061-gxv8y146	331	10	to	to	IN
cord-024061-gxv8y146	331	11	earlier	early	JJR
cord-024061-gxv8y146	331	12	strains	strain	NNS
cord-024061-gxv8y146	331	13	that	that	WDT
cord-024061-gxv8y146	331	14	emerged	emerge	VBD
cord-024061-gxv8y146	331	15	in	in	IN
cord-024061-gxv8y146	331	16	Minnesota	Minnesota	NNP
cord-024061-gxv8y146	331	17	and	and	CC
cord-024061-gxv8y146	331	18	dispersed	disperse	VBD
cord-024061-gxv8y146	331	19	into	into	IN
cord-024061-gxv8y146	331	20	Iowa	Iowa	NNP
cord-024061-gxv8y146	331	21	(	(	-LRB-
cord-024061-gxv8y146	331	22	120	120	CD
cord-024061-gxv8y146	331	23	)	)	-RRB-
cord-024061-gxv8y146	331	24	.	.	.
cord-024061-gxv8y146	332	1	Yet	yet	CC
cord-024061-gxv8y146	332	2	,	,	,
cord-024061-gxv8y146	332	3	both	both	CC
cord-024061-gxv8y146	332	4	HA	HA	NNP
cord-024061-gxv8y146	332	5	and	and	CC
cord-024061-gxv8y146	332	6	PB2	PB2	NNP
cord-024061-gxv8y146	332	7	segment	segment	NN
cord-024061-gxv8y146	332	8	agree	agree	VBP
cord-024061-gxv8y146	332	9	on	on	IN
cord-024061-gxv8y146	332	10	the	the	DT
cord-024061-gxv8y146	332	11	importance	importance	NN
cord-024061-gxv8y146	332	12	of	of	IN
cord-024061-gxv8y146	332	13	Iowa	Iowa	NNP
cord-024061-gxv8y146	332	14	as	as	IN
cord-024061-gxv8y146	332	15	a	a	DT
cord-024061-gxv8y146	332	16	geographical	geographical	JJ
cord-024061-gxv8y146	332	17	region	region	NN
cord-024061-gxv8y146	332	18	for	for	IN
cord-024061-gxv8y146	332	19	dispersal	dispersal	NN
cord-024061-gxv8y146	332	20	of	of	IN
cord-024061-gxv8y146	332	21	currently	currently	RB
cord-024061-gxv8y146	332	22	circulating	circulate	VBG
cord-024061-gxv8y146	332	23	H3	H3	NNP
cord-024061-gxv8y146	332	24	lineages	lineage	NNS
cord-024061-gxv8y146	332	25	(	(	-LRB-
cord-024061-gxv8y146	332	26	Figures	figure	NNS
cord-024061-gxv8y146	332	27	7H	7h	CD
cord-024061-gxv8y146	332	28	,	,	,
cord-024061-gxv8y146	332	29	8D	8D	NNP
cord-024061-gxv8y146	332	30	)	)	-RRB-
cord-024061-gxv8y146	332	31	.	.	.
cord-024061-gxv8y146	333	1	Additionally	additionally	RB
cord-024061-gxv8y146	333	2	,	,	,
cord-024061-gxv8y146	333	3	we	-PRON-	PRP
cord-024061-gxv8y146	333	4	inferred	infer	VBD
cord-024061-gxv8y146	333	5	two	two	CD
cord-024061-gxv8y146	333	6	significant	significant	JJ
cord-024061-gxv8y146	333	7	viral	viral	JJ
cord-024061-gxv8y146	333	8	dispersal	dispersal	NN
cord-024061-gxv8y146	333	9	routes	route	NNS
cord-024061-gxv8y146	333	10	originating	originate	VBG
cord-024061-gxv8y146	333	11	from	from	IN
cord-024061-gxv8y146	333	12	Kentucky	Kentucky	NNP
cord-024061-gxv8y146	333	13	to	to	IN
cord-024061-gxv8y146	333	14	Indiana	Indiana	NNP
cord-024061-gxv8y146	333	15	and	and	CC
cord-024061-gxv8y146	333	16	from	from	IN
cord-024061-gxv8y146	333	17	Ohio	Ohio	NNP
cord-024061-gxv8y146	333	18	to	to	IN
cord-024061-gxv8y146	333	19	Indiana	Indiana	NNP
cord-024061-gxv8y146	333	20	(	(	-LRB-
cord-024061-gxv8y146	333	21	Figure	Figure	NNP
cord-024061-gxv8y146	333	22	8D	8D	NNP
cord-024061-gxv8y146	333	23	)	)	-RRB-
cord-024061-gxv8y146	333	24	,	,	,
cord-024061-gxv8y146	333	25	which	which	WDT
cord-024061-gxv8y146	333	26	further	further	RB
cord-024061-gxv8y146	333	27	supports	support	VBZ
cord-024061-gxv8y146	333	28	the	the	DT
cord-024061-gxv8y146	333	29	role	role	NN
cord-024061-gxv8y146	333	30	of	of	IN
cord-024061-gxv8y146	333	31	exhibition	exhibition	NN
cord-024061-gxv8y146	333	32	of	of	IN
cord-024061-gxv8y146	333	33	swine	swine	NN
cord-024061-gxv8y146	333	34	movements	movement	NNS
cord-024061-gxv8y146	333	35	between	between	IN
cord-024061-gxv8y146	333	36	states	state	NNS
cord-024061-gxv8y146	333	37	in	in	IN
cord-024061-gxv8y146	333	38	maintaining	maintain	VBG
cord-024061-gxv8y146	333	39	the	the	DT
cord-024061-gxv8y146	333	40	spread	spread	NN
cord-024061-gxv8y146	333	41	of	of	IN
cord-024061-gxv8y146	333	42	H3	H3	NNP
cord-024061-gxv8y146	333	43	viruses	virus	NNS
cord-024061-gxv8y146	333	44	.	.	.
cord-024061-gxv8y146	334	1	Both	both	DT
cord-024061-gxv8y146	334	2	dispersal	dispersal	NN
cord-024061-gxv8y146	334	3	routes	route	NNS
cord-024061-gxv8y146	334	4	are	be	VBP
cord-024061-gxv8y146	334	5	mainly	mainly	RB
cord-024061-gxv8y146	334	6	maintained	maintain	VBN
cord-024061-gxv8y146	334	7	by	by	IN
cord-024061-gxv8y146	334	8	the	the	DT
cord-024061-gxv8y146	334	9	annual	annual	JJ
cord-024061-gxv8y146	334	10	agricultural	agricultural	JJ
cord-024061-gxv8y146	334	11	fairs	fair	NNS
cord-024061-gxv8y146	334	12	where	where	WRB
cord-024061-gxv8y146	334	13	exhibition	exhibition	NN
cord-024061-gxv8y146	334	14	susceptible	susceptible	JJ
cord-024061-gxv8y146	334	15	swine	swine	NN
cord-024061-gxv8y146	334	16	and	and	CC
cord-024061-gxv8y146	334	17	humans	human	NNS
cord-024061-gxv8y146	334	18	from	from	IN
cord-024061-gxv8y146	334	19	these	these	DT
cord-024061-gxv8y146	334	20	states	state	NNS
cord-024061-gxv8y146	334	21	are	be	VBP
cord-024061-gxv8y146	334	22	frequently	frequently	RB
cord-024061-gxv8y146	334	23	exposed	expose	VBN
cord-024061-gxv8y146	334	24	to	to	TO
cord-024061-gxv8y146	334	25	direct	direct	JJ
cord-024061-gxv8y146	334	26	and	and	CC
cord-024061-gxv8y146	334	27	indirect	indirect	JJ
cord-024061-gxv8y146	334	28	contacts	contact	NNS
cord-024061-gxv8y146	334	29	from	from	IN
cord-024061-gxv8y146	334	30	the	the	DT
cord-024061-gxv8y146	334	31	same	same	JJ
cord-024061-gxv8y146	334	32	infected	infected	JJ
cord-024061-gxv8y146	334	33	hosts	host	NNS
cord-024061-gxv8y146	334	34	(	(	-LRB-
cord-024061-gxv8y146	334	35	121	121	CD
cord-024061-gxv8y146	334	36	)	)	-RRB-
cord-024061-gxv8y146	334	37	.	.	.
cord-024061-gxv8y146	335	1	It	-PRON-	PRP
cord-024061-gxv8y146	335	2	is	be	VBZ
cord-024061-gxv8y146	335	3	worth	worth	JJ
cord-024061-gxv8y146	335	4	noting	note	VBG
cord-024061-gxv8y146	335	5	that	that	IN
cord-024061-gxv8y146	335	6	the	the	DT
cord-024061-gxv8y146	335	7	route	route	NN
cord-024061-gxv8y146	335	8	from	from	IN
cord-024061-gxv8y146	335	9	Kentucky	Kentucky	NNP
cord-024061-gxv8y146	335	10	to	to	IN
cord-024061-gxv8y146	335	11	Indiana	Indiana	NNP
cord-024061-gxv8y146	335	12	was	be	VBD
cord-024061-gxv8y146	335	13	hypothesized	hypothesize	VBN
cord-024061-gxv8y146	335	14	to	to	TO
cord-024061-gxv8y146	335	15	be	be	VB
cord-024061-gxv8y146	335	16	important	important	JJ
cord-024061-gxv8y146	335	17	for	for	IN
cord-024061-gxv8y146	335	18	H3	H3	NNP
cord-024061-gxv8y146	335	19	gene	gene	NN
cord-024061-gxv8y146	335	20	flow	flow	NN
cord-024061-gxv8y146	335	21	between	between	IN
cord-024061-gxv8y146	335	22	states	state	NNS
cord-024061-gxv8y146	335	23	,	,	,
cord-024061-gxv8y146	335	24	but	but	CC
cord-024061-gxv8y146	335	25	past	past	IN
cord-024061-gxv8y146	335	26	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	335	27	analyses	analysis	NNS
cord-024061-gxv8y146	335	28	did	do	VBD
cord-024061-gxv8y146	335	29	not	not	RB
cord-024061-gxv8y146	335	30	observe	observe	VB
cord-024061-gxv8y146	335	31	it	-PRON-	PRP
cord-024061-gxv8y146	335	32	due	due	IN
cord-024061-gxv8y146	335	33	to	to	IN
cord-024061-gxv8y146	335	34	the	the	DT
cord-024061-gxv8y146	335	35	lack	lack	NN
cord-024061-gxv8y146	335	36	of	of	IN
cord-024061-gxv8y146	335	37	sufficient	sufficient	JJ
cord-024061-gxv8y146	335	38	samples	sample	NNS
cord-024061-gxv8y146	335	39	(	(	-LRB-
cord-024061-gxv8y146	335	40	117	117	CD
cord-024061-gxv8y146	335	41	)	)	-RRB-
cord-024061-gxv8y146	335	42	.	.	.
cord-024061-gxv8y146	336	1	The	the	DT
cord-024061-gxv8y146	336	2	uneven	uneven	JJ
cord-024061-gxv8y146	336	3	sampling	sampling	NN
cord-024061-gxv8y146	336	4	of	of	IN
cord-024061-gxv8y146	336	5	sequences	sequence	NNS
cord-024061-gxv8y146	336	6	in	in	IN
cord-024061-gxv8y146	336	7	terms	term	NNS
cord-024061-gxv8y146	336	8	of	of	IN
cord-024061-gxv8y146	336	9	temporal	temporal	JJ
cord-024061-gxv8y146	336	10	depth	depth	NN
cord-024061-gxv8y146	336	11	and	and	CC
cord-024061-gxv8y146	336	12	frequency	frequency	NN
cord-024061-gxv8y146	336	13	of	of	IN
cord-024061-gxv8y146	336	14	associated	associated	JJ
cord-024061-gxv8y146	336	15	discrete	discrete	JJ
cord-024061-gxv8y146	336	16	traits	trait	NNS
cord-024061-gxv8y146	336	17	is	be	VBZ
cord-024061-gxv8y146	336	18	an	an	DT
cord-024061-gxv8y146	336	19	inherent	inherent	JJ
cord-024061-gxv8y146	336	20	limitation	limitation	NN
cord-024061-gxv8y146	336	21	of	of	IN
cord-024061-gxv8y146	336	22	most	most	JJS
cord-024061-gxv8y146	336	23	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	336	24	studies	study	NNS
cord-024061-gxv8y146	336	25	.	.	.
cord-024061-gxv8y146	337	1	For	for	IN
cord-024061-gxv8y146	337	2	example	example	NN
cord-024061-gxv8y146	337	3	,	,	,
cord-024061-gxv8y146	337	4	the	the	DT
cord-024061-gxv8y146	337	5	inclusion	inclusion	NN
cord-024061-gxv8y146	337	6	of	of	IN
cord-024061-gxv8y146	337	7	many	many	JJ
cord-024061-gxv8y146	337	8	recent	recent	JJ
cord-024061-gxv8y146	337	9	sequences	sequence	NNS
cord-024061-gxv8y146	337	10	from	from	IN
cord-024061-gxv8y146	337	11	a	a	DT
cord-024061-gxv8y146	337	12	single	single	JJ
cord-024061-gxv8y146	337	13	geographical	geographical	JJ
cord-024061-gxv8y146	337	14	location	location	NN
cord-024061-gxv8y146	337	15	may	may	MD
cord-024061-gxv8y146	337	16	lead	lead	VB
cord-024061-gxv8y146	337	17	to	to	IN
cord-024061-gxv8y146	337	18	a	a	DT
cord-024061-gxv8y146	337	19	biased	biased	JJ
cord-024061-gxv8y146	337	20	bottleneck	bottleneck	NN
cord-024061-gxv8y146	337	21	effect	effect	NN
cord-024061-gxv8y146	337	22	in	in	IN
cord-024061-gxv8y146	337	23	the	the	DT
cord-024061-gxv8y146	337	24	shape	shape	NN
cord-024061-gxv8y146	337	25	of	of	IN
cord-024061-gxv8y146	337	26	inferred	infer	VBN
cord-024061-gxv8y146	337	27	population	population	NN
cord-024061-gxv8y146	337	28	size	size	NN
cord-024061-gxv8y146	337	29	through	through	IN
cord-024061-gxv8y146	337	30	time	time	NN
cord-024061-gxv8y146	337	31	when	when	WRB
cord-024061-gxv8y146	337	32	using	use	VBG
cord-024061-gxv8y146	337	33	a	a	DT
cord-024061-gxv8y146	337	34	coalescent	coalescent	JJ
cord-024061-gxv8y146	337	35	model	model	NN
cord-024061-gxv8y146	337	36	from	from	IN
cord-024061-gxv8y146	337	37	the	the	DT
cord-024061-gxv8y146	337	38	Skyline	Skyline	NNP
cord-024061-gxv8y146	337	39	family	family	NN
cord-024061-gxv8y146	337	40	(	(	-LRB-
cord-024061-gxv8y146	337	41	122	122	CD
cord-024061-gxv8y146	337	42	)	)	-RRB-
cord-024061-gxv8y146	337	43	.	.	.
cord-024061-gxv8y146	338	1	This	this	DT
cord-024061-gxv8y146	338	2	issue	issue	NN
cord-024061-gxv8y146	338	3	can	can	MD
cord-024061-gxv8y146	338	4	be	be	VB
cord-024061-gxv8y146	338	5	resolved	resolve	VBN
cord-024061-gxv8y146	338	6	by	by	IN
cord-024061-gxv8y146	338	7	designing	design	VBG
cord-024061-gxv8y146	338	8	studies	study	NNS
cord-024061-gxv8y146	338	9	with	with	IN
cord-024061-gxv8y146	338	10	uniform	uniform	JJ
cord-024061-gxv8y146	338	11	probability	probability	NN
cord-024061-gxv8y146	338	12	sampling	sampling	NN
cord-024061-gxv8y146	338	13	with	with	IN
cord-024061-gxv8y146	338	14	respect	respect	NN
cord-024061-gxv8y146	338	15	to	to	IN
cord-024061-gxv8y146	338	16	space	space	NN
cord-024061-gxv8y146	338	17	and	and	CC
cord-024061-gxv8y146	338	18	time	time	NN
cord-024061-gxv8y146	338	19	(	(	-LRB-
cord-024061-gxv8y146	338	20	122	122	CD
cord-024061-gxv8y146	338	21	)	)	-RRB-
cord-024061-gxv8y146	338	22	.	.	.
cord-024061-gxv8y146	339	1	Further	further	RB
cord-024061-gxv8y146	339	2	,	,	,
cord-024061-gxv8y146	339	3	setting	set	VBG
cord-024061-gxv8y146	339	4	DTA	DTA	NNP
cord-024061-gxv8y146	339	5	is	be	VBZ
cord-024061-gxv8y146	339	6	user	user	NN
cord-024061-gxv8y146	339	7	friendly	friendly	JJ
cord-024061-gxv8y146	339	8	and	and	CC
cord-024061-gxv8y146	339	9	computationally	computationally	RB
cord-024061-gxv8y146	339	10	more	more	RBR
cord-024061-gxv8y146	339	11	efficient	efficient	JJ
cord-024061-gxv8y146	339	12	when	when	WRB
cord-024061-gxv8y146	339	13	compared	compare	VBN
cord-024061-gxv8y146	339	14	to	to	IN
cord-024061-gxv8y146	339	15	more	more	RBR
cord-024061-gxv8y146	339	16	complex	complex	JJ
cord-024061-gxv8y146	339	17	coalescent	coalescent	NN
cord-024061-gxv8y146	339	18	models	model	NNS
cord-024061-gxv8y146	339	19	,	,	,
cord-024061-gxv8y146	339	20	but	but	CC
cord-024061-gxv8y146	339	21	it	-PRON-	PRP
cord-024061-gxv8y146	339	22	underlays	underlay	VBZ
cord-024061-gxv8y146	339	23	a	a	DT
cord-024061-gxv8y146	339	24	few	few	JJ
cord-024061-gxv8y146	339	25	assumptions	assumption	NNS
cord-024061-gxv8y146	339	26	,	,	,
cord-024061-gxv8y146	339	27	such	such	JJ
cord-024061-gxv8y146	339	28	as	as	IN
cord-024061-gxv8y146	339	29	that	that	IN
cord-024061-gxv8y146	339	30	the	the	DT
cord-024061-gxv8y146	339	31	sequence	sequence	NN
cord-024061-gxv8y146	339	32	sample	sample	NN
cord-024061-gxv8y146	339	33	size	size	NN
cord-024061-gxv8y146	339	34	is	be	VBZ
cord-024061-gxv8y146	339	35	proportional	proportional	JJ
cord-024061-gxv8y146	339	36	to	to	IN
cord-024061-gxv8y146	339	37	the	the	DT
cord-024061-gxv8y146	339	38	size	size	NN
cord-024061-gxv8y146	339	39	of	of	IN
cord-024061-gxv8y146	339	40	the	the	DT
cord-024061-gxv8y146	339	41	selected	select	VBN
cord-024061-gxv8y146	339	42	discrete	discrete	JJ
cord-024061-gxv8y146	339	43	state	state	NN
cord-024061-gxv8y146	339	44	(	(	-LRB-
cord-024061-gxv8y146	339	45	26	26	CD
cord-024061-gxv8y146	339	46	)	)	-RRB-
cord-024061-gxv8y146	339	47	.	.	.
cord-024061-gxv8y146	340	1	Thus	thus	RB
cord-024061-gxv8y146	340	2	,	,	,
cord-024061-gxv8y146	340	3	including	include	VBG
cord-024061-gxv8y146	340	4	sequences	sequence	NNS
cord-024061-gxv8y146	340	5	from	from	IN
cord-024061-gxv8y146	340	6	severely	severely	RB
cord-024061-gxv8y146	340	7	undersampled	undersampled	JJ
cord-024061-gxv8y146	340	8	discrete	discrete	JJ
cord-024061-gxv8y146	340	9	traits	trait	NNS
cord-024061-gxv8y146	340	10	will	will	MD
cord-024061-gxv8y146	340	11	tend	tend	VB
cord-024061-gxv8y146	340	12	to	to	TO
cord-024061-gxv8y146	340	13	produce	produce	VB
cord-024061-gxv8y146	340	14	unreliable	unreliable	JJ
cord-024061-gxv8y146	340	15	posterior	posterior	JJ
cord-024061-gxv8y146	340	16	inferences	inference	NNS
cord-024061-gxv8y146	340	17	,	,	,
cord-024061-gxv8y146	340	18	where	where	WRB
cord-024061-gxv8y146	340	19	for	for	IN
cord-024061-gxv8y146	340	20	example	example	NN
cord-024061-gxv8y146	340	21	,	,	,
cord-024061-gxv8y146	340	22	inferred	infer	VBN
cord-024061-gxv8y146	340	23	RSPPs	rspp	NNS
cord-024061-gxv8y146	340	24	will	will	MD
cord-024061-gxv8y146	340	25	be	be	VB
cord-024061-gxv8y146	340	26	skewed	skewed	JJ
cord-024061-gxv8y146	340	27	toward	toward	IN
cord-024061-gxv8y146	340	28	oversampled	oversample	VBN
cord-024061-gxv8y146	340	29	areas	area	NNS
cord-024061-gxv8y146	340	30	.	.	.
cord-024061-gxv8y146	341	1	Nevertheless	nevertheless	RB
cord-024061-gxv8y146	341	2	,	,	,
cord-024061-gxv8y146	341	3	undersampling	undersampling	NN
cord-024061-gxv8y146	341	4	is	be	VBZ
cord-024061-gxv8y146	341	5	a	a	DT
cord-024061-gxv8y146	341	6	common	common	JJ
cord-024061-gxv8y146	341	7	problem	problem	NN
cord-024061-gxv8y146	341	8	,	,	,
cord-024061-gxv8y146	341	9	especially	especially	RB
cord-024061-gxv8y146	341	10	in	in	IN
cord-024061-gxv8y146	341	11	passive	passive	JJ
cord-024061-gxv8y146	341	12	surveillance	surveillance	NN
cord-024061-gxv8y146	341	13	data	datum	NNS
cord-024061-gxv8y146	341	14	,	,	,
cord-024061-gxv8y146	341	15	and	and	CC
cord-024061-gxv8y146	341	16	therefore	therefore	RB
cord-024061-gxv8y146	341	17	,	,	,
cord-024061-gxv8y146	341	18	the	the	DT
cord-024061-gxv8y146	341	19	use	use	NN
cord-024061-gxv8y146	341	20	of	of	IN
cord-024061-gxv8y146	341	21	structural	structural	JJ
cord-024061-gxv8y146	341	22	coalescent	coalescent	NN
cord-024061-gxv8y146	341	23	models	model	NNS
cord-024061-gxv8y146	341	24	(	(	-LRB-
cord-024061-gxv8y146	341	25	e.g.	e.g.	RB
cord-024061-gxv8y146	341	26	,	,	,
cord-024061-gxv8y146	341	27	BASTA	BASTA	NNP
cord-024061-gxv8y146	341	28	)	)	-RRB-
cord-024061-gxv8y146	341	29	might	may	MD
cord-024061-gxv8y146	341	30	be	be	VB
cord-024061-gxv8y146	341	31	more	more	RBR
cord-024061-gxv8y146	341	32	appropriate	appropriate	JJ
cord-024061-gxv8y146	341	33	(	(	-LRB-
cord-024061-gxv8y146	341	34	26	26	CD
cord-024061-gxv8y146	341	35	)	)	-RRB-
cord-024061-gxv8y146	341	36	.	.	.
cord-024061-gxv8y146	342	1	Despite	despite	IN
cord-024061-gxv8y146	342	2	this	this	DT
cord-024061-gxv8y146	342	3	inherited	inherit	VBN
cord-024061-gxv8y146	342	4	sensitivity	sensitivity	NN
cord-024061-gxv8y146	342	5	of	of	IN
cord-024061-gxv8y146	342	6	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	342	7	methods	method	NNS
cord-024061-gxv8y146	342	8	to	to	IN
cord-024061-gxv8y146	342	9	uneven	uneven	JJ
cord-024061-gxv8y146	342	10	sampling	sampling	NN
cord-024061-gxv8y146	342	11	,	,	,
cord-024061-gxv8y146	342	12	our	-PRON-	PRP$
cord-024061-gxv8y146	342	13	posterior	posterior	JJ
cord-024061-gxv8y146	342	14	inference	inference	NN
cord-024061-gxv8y146	342	15	from	from	IN
cord-024061-gxv8y146	342	16	the	the	DT
cord-024061-gxv8y146	342	17	best	good	JJS
cord-024061-gxv8y146	342	18	fitting	fitting	JJ
cord-024061-gxv8y146	342	19	models	model	NNS
cord-024061-gxv8y146	342	20	showed	show	VBD
cord-024061-gxv8y146	342	21	remarkable	remarkable	JJ
cord-024061-gxv8y146	342	22	robustness	robustness	NN
cord-024061-gxv8y146	342	23	toward	toward	IN
cord-024061-gxv8y146	342	24	such	such	JJ
cord-024061-gxv8y146	342	25	limitation	limitation	NN
cord-024061-gxv8y146	342	26	.	.	.
cord-024061-gxv8y146	343	1	Although	although	IN
cord-024061-gxv8y146	343	2	the	the	DT
cord-024061-gxv8y146	343	3	largest	large	JJS
cord-024061-gxv8y146	343	4	number	number	NN
cord-024061-gxv8y146	343	5	of	of	IN
cord-024061-gxv8y146	343	6	collected	collect	VBN
cord-024061-gxv8y146	343	7	sequences	sequence	NNS
cord-024061-gxv8y146	343	8	was	be	VBD
cord-024061-gxv8y146	343	9	in	in	IN
cord-024061-gxv8y146	343	10	2017	2017	CD
cord-024061-gxv8y146	343	11	(	(	-LRB-
cord-024061-gxv8y146	343	12	80	80	CD
cord-024061-gxv8y146	343	13	)	)	-RRB-
cord-024061-gxv8y146	344	1	(	(	-LRB-
cord-024061-gxv8y146	344	2	Supplementary	Supplementary	NNP
cord-024061-gxv8y146	344	3	Table	Table	NNP
cord-024061-gxv8y146	344	4	2	2	CD
cord-024061-gxv8y146	344	5	)	)	-RRB-
cord-024061-gxv8y146	344	6	,	,	,
cord-024061-gxv8y146	344	7	estimates	estimate	NNS
cord-024061-gxv8y146	344	8	of	of	IN
cord-024061-gxv8y146	344	9	relative	relative	JJ
cord-024061-gxv8y146	344	10	genetic	genetic	JJ
cord-024061-gxv8y146	344	11	diversity	diversity	NN
cord-024061-gxv8y146	344	12	through	through	IN
cord-024061-gxv8y146	344	13	time	time	NN
cord-024061-gxv8y146	344	14	did	do	VBD
cord-024061-gxv8y146	344	15	not	not	RB
cord-024061-gxv8y146	344	16	show	show	VB
cord-024061-gxv8y146	344	17	any	any	DT
cord-024061-gxv8y146	344	18	striking	strike	VBG
cord-024061-gxv8y146	344	19	jumps	jump	NNS
cord-024061-gxv8y146	344	20	in	in	IN
cord-024061-gxv8y146	344	21	that	that	DT
cord-024061-gxv8y146	344	22	year	year	NN
cord-024061-gxv8y146	344	23	for	for	IN
cord-024061-gxv8y146	344	24	both	both	CC
cord-024061-gxv8y146	344	25	HA	HA	NNP
cord-024061-gxv8y146	344	26	and	and	CC
cord-024061-gxv8y146	344	27	PB2	pb2	NN
cord-024061-gxv8y146	344	28	segments	segment	NNS
cord-024061-gxv8y146	344	29	(	(	-LRB-
cord-024061-gxv8y146	344	30	Figures	figure	NNS
cord-024061-gxv8y146	344	31	4B	4b	NN
cord-024061-gxv8y146	344	32	,	,	,
cord-024061-gxv8y146	344	33	2D	2D	NNP
cord-024061-gxv8y146	344	34	)	)	-RRB-
cord-024061-gxv8y146	344	35	.	.	.
cord-024061-gxv8y146	345	1	Additionally	additionally	RB
cord-024061-gxv8y146	345	2	,	,	,
cord-024061-gxv8y146	345	3	for	for	IN
cord-024061-gxv8y146	345	4	the	the	DT
cord-024061-gxv8y146	345	5	HA	HA	NNP
cord-024061-gxv8y146	345	6	gene	gene	NN
cord-024061-gxv8y146	345	7	,	,	,
cord-024061-gxv8y146	345	8	Iowa	Iowa	NNP
cord-024061-gxv8y146	345	9	(	(	-LRB-
cord-024061-gxv8y146	345	10	with	with	IN
cord-024061-gxv8y146	345	11	26	26	CD
cord-024061-gxv8y146	345	12	sequences	sequence	NNS
cord-024061-gxv8y146	345	13	)	)	-RRB-
cord-024061-gxv8y146	345	14	rather	rather	RB
cord-024061-gxv8y146	345	15	than	than	IN
cord-024061-gxv8y146	345	16	Ohio	Ohio	NNP
cord-024061-gxv8y146	345	17	(	(	-LRB-
cord-024061-gxv8y146	345	18	39	39	CD
cord-024061-gxv8y146	345	19	sequences	sequence	NNS
cord-024061-gxv8y146	345	20	)	)	-RRB-
cord-024061-gxv8y146	345	21	was	be	VBD
cord-024061-gxv8y146	345	22	inferred	infer	VBN
cord-024061-gxv8y146	345	23	as	as	IN
cord-024061-gxv8y146	345	24	the	the	DT
cord-024061-gxv8y146	345	25	ancestral	ancestral	JJ
cord-024061-gxv8y146	345	26	location	location	NN
cord-024061-gxv8y146	345	27	(	(	-LRB-
cord-024061-gxv8y146	345	28	Figure	figure	NN
cord-024061-gxv8y146	345	29	5H	5h	NN
cord-024061-gxv8y146	345	30	,	,	,
cord-024061-gxv8y146	345	31	Supplementary	Supplementary	NNP
cord-024061-gxv8y146	345	32	Table	Table	NNP
cord-024061-gxv8y146	345	33	2	2	CD
cord-024061-gxv8y146	345	34	)	)	-RRB-
cord-024061-gxv8y146	345	35	.	.	.
cord-024061-gxv8y146	346	1	However	however	RB
cord-024061-gxv8y146	346	2	,	,	,
cord-024061-gxv8y146	346	3	seven	seven	CD
cord-024061-gxv8y146	346	4	out	out	IN
cord-024061-gxv8y146	346	5	of	of	IN
cord-024061-gxv8y146	346	6	the	the	DT
cord-024061-gxv8y146	346	7	17	17	CD
cord-024061-gxv8y146	346	8	U.S.	U.S.	NNP
cord-024061-gxv8y146	346	9	states	state	NNS
cord-024061-gxv8y146	346	10	were	be	VBD
cord-024061-gxv8y146	346	11	excluded	exclude	VBN
cord-024061-gxv8y146	346	12	from	from	IN
cord-024061-gxv8y146	346	13	the	the	DT
cord-024061-gxv8y146	346	14	DTA	DTA	NNP
cord-024061-gxv8y146	346	15	due	due	IN
cord-024061-gxv8y146	346	16	to	to	IN
cord-024061-gxv8y146	346	17	the	the	DT
cord-024061-gxv8y146	346	18	lack	lack	NN
cord-024061-gxv8y146	346	19	of	of	IN
cord-024061-gxv8y146	346	20	sufficient	sufficient	JJ
cord-024061-gxv8y146	346	21	sequences	sequence	NNS
cord-024061-gxv8y146	346	22	,	,	,
cord-024061-gxv8y146	346	23	and	and	CC
cord-024061-gxv8y146	346	24	therefore	therefore	RB
cord-024061-gxv8y146	346	25	,	,	,
cord-024061-gxv8y146	346	26	their	-PRON-	PRP$
cord-024061-gxv8y146	346	27	role	role	NN
cord-024061-gxv8y146	346	28	was	be	VBD
cord-024061-gxv8y146	346	29	unquantified	unquantified	JJ
cord-024061-gxv8y146	346	30	in	in	IN
cord-024061-gxv8y146	346	31	shaping	shape	VBG
cord-024061-gxv8y146	346	32	the	the	DT
cord-024061-gxv8y146	346	33	spatio	spatio	JJ
cord-024061-gxv8y146	346	34	-	-	HYPH
cord-024061-gxv8y146	346	35	temporal	temporal	JJ
cord-024061-gxv8y146	346	36	evolution	evolution	NN
cord-024061-gxv8y146	346	37	of	of	IN
cord-024061-gxv8y146	346	38	SI	SI	NNP
cord-024061-gxv8y146	346	39	.	.	.
cord-024061-gxv8y146	347	1	Yet	yet	CC
cord-024061-gxv8y146	347	2	,	,	,
cord-024061-gxv8y146	347	3	these	these	DT
cord-024061-gxv8y146	347	4	states	state	NNS
cord-024061-gxv8y146	347	5	had	have	VBD
cord-024061-gxv8y146	347	6	substantially	substantially	RB
cord-024061-gxv8y146	347	7	fewer	few	JJR
cord-024061-gxv8y146	347	8	swine	swine	NN
cord-024061-gxv8y146	347	9	-	-	HYPH
cord-024061-gxv8y146	347	10	related	relate	VBN
cord-024061-gxv8y146	347	11	activities	activity	NNS
cord-024061-gxv8y146	347	12	as	as	RB
cord-024061-gxv8y146	347	13	well	well	RB
cord-024061-gxv8y146	347	14	as	as	IN
cord-024061-gxv8y146	347	15	SI	SI	NNP
cord-024061-gxv8y146	347	16	outbreaks	outbreak	NNS
cord-024061-gxv8y146	347	17	than	than	IN
cord-024061-gxv8y146	347	18	analyzed	analyze	VBN
cord-024061-gxv8y146	347	19	states	state	NNS
cord-024061-gxv8y146	347	20	.	.	.
cord-024061-gxv8y146	348	1	Further	further	RB
cord-024061-gxv8y146	348	2	,	,	,
cord-024061-gxv8y146	348	3	we	-PRON-	PRP
cord-024061-gxv8y146	348	4	showed	show	VBD
cord-024061-gxv8y146	348	5	how	how	WRB
cord-024061-gxv8y146	348	6	the	the	DT
cord-024061-gxv8y146	348	7	posterior	posterior	JJ
cord-024061-gxv8y146	348	8	estimates	estimate	NNS
cord-024061-gxv8y146	348	9	of	of	IN
cord-024061-gxv8y146	348	10	demographic	demographic	JJ
cord-024061-gxv8y146	348	11	reconstruction	reconstruction	NN
cord-024061-gxv8y146	348	12	were	be	VBD
cord-024061-gxv8y146	348	13	almost	almost	RB
cord-024061-gxv8y146	348	14	insensitive	insensitive	JJ
cord-024061-gxv8y146	348	15	to	to	IN
cord-024061-gxv8y146	348	16	the	the	DT
cord-024061-gxv8y146	348	17	choice	choice	NN
cord-024061-gxv8y146	348	18	of	of	IN
cord-024061-gxv8y146	348	19	different	different	JJ
cord-024061-gxv8y146	348	20	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	348	21	priors	prior	NNS
cord-024061-gxv8y146	348	22	for	for	IN
cord-024061-gxv8y146	348	23	each	each	DT
cord-024061-gxv8y146	348	24	gene	gene	NN
cord-024061-gxv8y146	348	25	segment	segment	NN
cord-024061-gxv8y146	348	26	(	(	-LRB-
cord-024061-gxv8y146	348	27	Figures	figure	NNS
cord-024061-gxv8y146	348	28	2	2	CD
cord-024061-gxv8y146	348	29	-	-	SYM
cord-024061-gxv8y146	348	30	4	4	CD
cord-024061-gxv8y146	348	31	)	)	-RRB-
cord-024061-gxv8y146	348	32	.	.	.
cord-024061-gxv8y146	349	1	However	however	RB
cord-024061-gxv8y146	349	2	,	,	,
cord-024061-gxv8y146	349	3	inferred	infer	VBD
cord-024061-gxv8y146	349	4	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	349	5	estimates	estimate	NNS
cord-024061-gxv8y146	349	6	from	from	IN
cord-024061-gxv8y146	349	7	different	different	JJ
cord-024061-gxv8y146	349	8	gene	gene	NN
cord-024061-gxv8y146	349	9	regions	region	NNS
cord-024061-gxv8y146	349	10	may	may	MD
cord-024061-gxv8y146	349	11	differ	differ	VB
cord-024061-gxv8y146	349	12	(	(	-LRB-
cord-024061-gxv8y146	349	13	41	41	CD
cord-024061-gxv8y146	349	14	)	)	-RRB-
cord-024061-gxv8y146	349	15	or	or	CC
cord-024061-gxv8y146	349	16	coincide	coincide	VB
cord-024061-gxv8y146	349	17	(	(	-LRB-
cord-024061-gxv8y146	349	18	118	118	CD
cord-024061-gxv8y146	349	19	)	)	-RRB-
cord-024061-gxv8y146	349	20	due	due	IN
cord-024061-gxv8y146	349	21	to	to	IN
cord-024061-gxv8y146	349	22	the	the	DT
cord-024061-gxv8y146	349	23	natural	natural	JJ
cord-024061-gxv8y146	349	24	variation	variation	NN
cord-024061-gxv8y146	349	25	in	in	IN
cord-024061-gxv8y146	349	26	their	-PRON-	PRP$
cord-024061-gxv8y146	349	27	mutation	mutation	NN
cord-024061-gxv8y146	349	28	rate	rate	NN
cord-024061-gxv8y146	349	29	over	over	IN
cord-024061-gxv8y146	349	30	time	time	NN
cord-024061-gxv8y146	349	31	.	.	.
cord-024061-gxv8y146	350	1	This	this	DT
cord-024061-gxv8y146	350	2	raises	raise	VBZ
cord-024061-gxv8y146	350	3	the	the	DT
cord-024061-gxv8y146	350	4	question	question	NN
cord-024061-gxv8y146	350	5	of	of	IN
cord-024061-gxv8y146	350	6	whether	whether	IN
cord-024061-gxv8y146	350	7	using	use	VBG
cord-024061-gxv8y146	350	8	longer	long	JJR
cord-024061-gxv8y146	350	9	gene	gene	NN
cord-024061-gxv8y146	350	10	segments	segment	NNS
cord-024061-gxv8y146	350	11	or	or	CC
cord-024061-gxv8y146	350	12	whole	whole	JJ
cord-024061-gxv8y146	350	13	genomes	genome	NNS
cord-024061-gxv8y146	350	14	provides	provide	VBZ
cord-024061-gxv8y146	350	15	deeper	deep	JJR
cord-024061-gxv8y146	350	16	resolution	resolution	NN
cord-024061-gxv8y146	350	17	into	into	IN
cord-024061-gxv8y146	350	18	the	the	DT
cord-024061-gxv8y146	350	19	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	350	20	history	history	NN
cord-024061-gxv8y146	350	21	of	of	IN
cord-024061-gxv8y146	350	22	rapidly	rapidly	RB
cord-024061-gxv8y146	350	23	evolving	evolve	VBG
cord-024061-gxv8y146	350	24	pathogens	pathogen	NNS
cord-024061-gxv8y146	350	25	.	.	.
cord-024061-gxv8y146	351	1	Past	past	JJ
cord-024061-gxv8y146	351	2	influenza	influenza	NN
cord-024061-gxv8y146	351	3	A	a	DT
cord-024061-gxv8y146	351	4	studies	study	NNS
cord-024061-gxv8y146	351	5	(	(	-LRB-
cord-024061-gxv8y146	351	6	41	41	CD
cord-024061-gxv8y146	351	7	,	,	,
cord-024061-gxv8y146	351	8	123	123	CD
cord-024061-gxv8y146	351	9	,	,	,
cord-024061-gxv8y146	351	10	124	124	CD
cord-024061-gxv8y146	351	11	)	)	-RRB-
cord-024061-gxv8y146	351	12	,	,	,
cord-024061-gxv8y146	351	13	including	include	VBG
cord-024061-gxv8y146	351	14	the	the	DT
cord-024061-gxv8y146	351	15	present	present	JJ
cord-024061-gxv8y146	351	16	study	study	NN
cord-024061-gxv8y146	351	17	,	,	,
cord-024061-gxv8y146	351	18	showed	show	VBD
cord-024061-gxv8y146	351	19	that	that	IN
cord-024061-gxv8y146	351	20	HA	HA	NNP
cord-024061-gxv8y146	351	21	and	and	CC
cord-024061-gxv8y146	351	22	NA	NA	NNP
cord-024061-gxv8y146	351	23	segments	segment	NNS
cord-024061-gxv8y146	351	24	typically	typically	RB
cord-024061-gxv8y146	351	25	exhibit	exhibit	VBP
cord-024061-gxv8y146	351	26	higher	high	JJR
cord-024061-gxv8y146	351	27	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	351	28	rates	rate	NNS
cord-024061-gxv8y146	351	29	than	than	IN
cord-024061-gxv8y146	351	30	more	more	JJR
cord-024061-gxv8y146	351	31	conserved	conserve	VBN
cord-024061-gxv8y146	351	32	segments	segment	NNS
cord-024061-gxv8y146	351	33	like	like	IN
cord-024061-gxv8y146	351	34	PB1	PB1	NNP
cord-024061-gxv8y146	351	35	and	and	CC
cord-024061-gxv8y146	351	36	PB2	PB2	NNP
cord-024061-gxv8y146	351	37	.	.	.
cord-024061-gxv8y146	352	1	Subsequently	subsequently	RB
cord-024061-gxv8y146	352	2	,	,	,
cord-024061-gxv8y146	352	3	segments	segment	NNS
cord-024061-gxv8y146	352	4	with	with	IN
cord-024061-gxv8y146	352	5	higher	high	JJR
cord-024061-gxv8y146	352	6	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	352	7	rate	rate	NN
cord-024061-gxv8y146	352	8	will	will	MD
cord-024061-gxv8y146	352	9	also	also	RB
cord-024061-gxv8y146	352	10	display	display	VB
cord-024061-gxv8y146	352	11	stronger	strong	JJR
cord-024061-gxv8y146	352	12	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	352	13	signals	signal	NNS
cord-024061-gxv8y146	352	14	,	,	,
cord-024061-gxv8y146	352	15	as	as	IN
cord-024061-gxv8y146	352	16	described	describe	VBN
cord-024061-gxv8y146	352	17	above	above	RB
cord-024061-gxv8y146	352	18	.	.	.
cord-024061-gxv8y146	353	1	In	in	IN
cord-024061-gxv8y146	353	2	our	-PRON-	PRP$
cord-024061-gxv8y146	353	3	analyses	analysis	NNS
cord-024061-gxv8y146	353	4	,	,	,
cord-024061-gxv8y146	353	5	the	the	DT
cord-024061-gxv8y146	353	6	width	width	NN
cord-024061-gxv8y146	353	7	of	of	IN
cord-024061-gxv8y146	353	8	the	the	DT
cord-024061-gxv8y146	353	9	95	95	CD
cord-024061-gxv8y146	353	10	%	%	NN
cord-024061-gxv8y146	353	11	HPDs	hpd	NNS
cord-024061-gxv8y146	353	12	(	(	-LRB-
cord-024061-gxv8y146	353	13	i.e.	i.e.	FW
cord-024061-gxv8y146	353	14	,	,	,
cord-024061-gxv8y146	353	15	length	length	NN
cord-024061-gxv8y146	353	16	of	of	IN
cord-024061-gxv8y146	353	17	the	the	DT
cord-024061-gxv8y146	353	18	time	time	NN
cord-024061-gxv8y146	353	19	scale	scale	NN
cord-024061-gxv8y146	353	20	)	)	-RRB-
cord-024061-gxv8y146	353	21	for	for	IN
cord-024061-gxv8y146	353	22	the	the	DT
cord-024061-gxv8y146	353	23	median	median	JJ
cord-024061-gxv8y146	353	24	age	age	NN
cord-024061-gxv8y146	353	25	and	and	CC
cord-024061-gxv8y146	353	26	TMRCAs	tmrca	NNS
cord-024061-gxv8y146	353	27	of	of	IN
cord-024061-gxv8y146	353	28	PB2	PB2	NNP
cord-024061-gxv8y146	353	29	were	be	VBD
cord-024061-gxv8y146	353	30	remarkably	remarkably	RB
cord-024061-gxv8y146	353	31	wider	wide	JJR
cord-024061-gxv8y146	353	32	than	than	IN
cord-024061-gxv8y146	353	33	the	the	DT
cord-024061-gxv8y146	353	34	HA	HA	NNP
cord-024061-gxv8y146	353	35	segment	segment	NN
cord-024061-gxv8y146	353	36	(	(	-LRB-
cord-024061-gxv8y146	353	37	Figures	figure	NNS
cord-024061-gxv8y146	353	38	2	2	CD
cord-024061-gxv8y146	353	39	,	,	,
cord-024061-gxv8y146	353	40	3	3	CD
cord-024061-gxv8y146	353	41	)	)	-RRB-
cord-024061-gxv8y146	353	42	.	.	.
cord-024061-gxv8y146	354	1	This	this	DT
cord-024061-gxv8y146	354	2	sizeable	sizeable	JJ
cord-024061-gxv8y146	354	3	width	width	NN
cord-024061-gxv8y146	354	4	of	of	IN
cord-024061-gxv8y146	354	5	the	the	DT
cord-024061-gxv8y146	354	6	posterior	posterior	JJ
cord-024061-gxv8y146	354	7	intervals	interval	NNS
cord-024061-gxv8y146	354	8	reflects	reflect	VBZ
cord-024061-gxv8y146	354	9	the	the	DT
cord-024061-gxv8y146	354	10	magnitude	magnitude	NN
cord-024061-gxv8y146	354	11	of	of	IN
cord-024061-gxv8y146	354	12	uncertainty	uncertainty	NN
cord-024061-gxv8y146	354	13	surrounding	surround	VBG
cord-024061-gxv8y146	354	14	inferences	inference	NNS
cord-024061-gxv8y146	354	15	from	from	IN
cord-024061-gxv8y146	354	16	the	the	DT
cord-024061-gxv8y146	354	17	PB2	PB2	NNP
cord-024061-gxv8y146	354	18	segment	segment	NN
cord-024061-gxv8y146	354	19	,	,	,
cord-024061-gxv8y146	354	20	as	as	RB
cord-024061-gxv8y146	354	21	well	well	RB
cord-024061-gxv8y146	354	22	as	as	IN
cord-024061-gxv8y146	354	23	suggests	suggest	VBZ
cord-024061-gxv8y146	354	24	that	that	IN
cord-024061-gxv8y146	354	25	inferences	inference	NNS
cord-024061-gxv8y146	354	26	from	from	IN
cord-024061-gxv8y146	354	27	the	the	DT
cord-024061-gxv8y146	354	28	HA	HA	NNP
cord-024061-gxv8y146	354	29	segment	segment	NN
cord-024061-gxv8y146	354	30	were	be	VBD
cord-024061-gxv8y146	354	31	more	more	RBR
cord-024061-gxv8y146	354	32	precise	precise	JJ
cord-024061-gxv8y146	354	33	(	(	-LRB-
cord-024061-gxv8y146	354	34	or	or	CC
cord-024061-gxv8y146	354	35	robust	robust	JJ
cord-024061-gxv8y146	354	36	)	)	-RRB-
cord-024061-gxv8y146	354	37	than	than	IN
cord-024061-gxv8y146	354	38	the	the	DT
cord-024061-gxv8y146	354	39	PB2	PB2	NNP
cord-024061-gxv8y146	354	40	segment	segment	NN
cord-024061-gxv8y146	354	41	.	.	.
cord-024061-gxv8y146	355	1	Also	also	RB
cord-024061-gxv8y146	355	2	,	,	,
cord-024061-gxv8y146	355	3	we	-PRON-	PRP
cord-024061-gxv8y146	355	4	demonstrated	demonstrate	VBD
cord-024061-gxv8y146	355	5	how	how	WRB
cord-024061-gxv8y146	355	6	the	the	DT
cord-024061-gxv8y146	355	7	PB2	PB2	NNP
cord-024061-gxv8y146	355	8	segment	segment	NN
cord-024061-gxv8y146	355	9	failed	fail	VBD
cord-024061-gxv8y146	355	10	to	to	TO
cord-024061-gxv8y146	355	11	identify	identify	VB
cord-024061-gxv8y146	355	12	the	the	DT
cord-024061-gxv8y146	355	13	ancestral	ancestral	JJ
cord-024061-gxv8y146	355	14	geographical	geographical	JJ
cord-024061-gxv8y146	355	15	location	location	NN
cord-024061-gxv8y146	355	16	of	of	IN
cord-024061-gxv8y146	355	17	currently	currently	RB
cord-024061-gxv8y146	355	18	circulating	circulate	VBG
cord-024061-gxv8y146	355	19	H3	H3	NNP
cord-024061-gxv8y146	355	20	viruses	virus	NNS
cord-024061-gxv8y146	355	21	(	(	-LRB-
cord-024061-gxv8y146	355	22	Figure	Figure	NNP
cord-024061-gxv8y146	355	23	6D	6d	NN
cord-024061-gxv8y146	355	24	)	)	-RRB-
cord-024061-gxv8y146	355	25	.	.	.
cord-024061-gxv8y146	356	1	While	while	IN
cord-024061-gxv8y146	356	2	,	,	,
cord-024061-gxv8y146	356	3	using	use	VBG
cord-024061-gxv8y146	356	4	the	the	DT
cord-024061-gxv8y146	356	5	symmetric	symmetric	JJ
cord-024061-gxv8y146	356	6	model	model	NN
cord-024061-gxv8y146	356	7	,	,	,
cord-024061-gxv8y146	356	8	we	-PRON-	PRP
cord-024061-gxv8y146	356	9	inferred	infer	VBD
cord-024061-gxv8y146	356	10	four	four	CD
cord-024061-gxv8y146	356	11	candidate	candidate	NN
cord-024061-gxv8y146	356	12	ancestral	ancestral	JJ
cord-024061-gxv8y146	356	13	locations	location	NNS
cord-024061-gxv8y146	356	14	with	with	IN
cord-024061-gxv8y146	356	15	inconclusive	inconclusive	JJ
cord-024061-gxv8y146	356	16	RSPPs	rspp	NNS
cord-024061-gxv8y146	356	17	(	(	-LRB-
cord-024061-gxv8y146	356	18	Figure	figure	NN
cord-024061-gxv8y146	356	19	6H	6h	CD
cord-024061-gxv8y146	356	20	)	)	-RRB-
cord-024061-gxv8y146	356	21	.	.	.
cord-024061-gxv8y146	357	1	Further	further	RB
cord-024061-gxv8y146	357	2	,	,	,
cord-024061-gxv8y146	357	3	Nelson	Nelson	NNP
cord-024061-gxv8y146	357	4	et	et	NNP
cord-024061-gxv8y146	357	5	al	al	NNP
cord-024061-gxv8y146	357	6	.	.	.
cord-024061-gxv8y146	358	1	(	(	-LRB-
cord-024061-gxv8y146	358	2	117	117	CD
cord-024061-gxv8y146	358	3	)	)	-RRB-
cord-024061-gxv8y146	358	4	were	be	VBD
cord-024061-gxv8y146	358	5	not	not	RB
cord-024061-gxv8y146	358	6	able	able	JJ
cord-024061-gxv8y146	358	7	to	to	TO
cord-024061-gxv8y146	358	8	infer	infer	VB
cord-024061-gxv8y146	358	9	a	a	DT
cord-024061-gxv8y146	358	10	significant	significant	JJ
cord-024061-gxv8y146	358	11	migration	migration	NN
cord-024061-gxv8y146	358	12	route	route	NN
cord-024061-gxv8y146	358	13	between	between	IN
cord-024061-gxv8y146	358	14	Indiana	Indiana	NNP
cord-024061-gxv8y146	358	15	and	and	CC
cord-024061-gxv8y146	358	16	Ohio	Ohio	NNP
cord-024061-gxv8y146	358	17	using	use	VBG
cord-024061-gxv8y146	358	18	the	the	DT
cord-024061-gxv8y146	358	19	PB2	PB2	NNP
cord-024061-gxv8y146	358	20	segment	segment	NN
cord-024061-gxv8y146	358	21	.	.	.
cord-024061-gxv8y146	359	1	Yet	yet	CC
cord-024061-gxv8y146	359	2	,	,	,
cord-024061-gxv8y146	359	3	we	-PRON-	PRP
cord-024061-gxv8y146	359	4	were	be	VBD
cord-024061-gxv8y146	359	5	able	able	JJ
cord-024061-gxv8y146	359	6	to	to	TO
cord-024061-gxv8y146	359	7	infer	infer	VB
cord-024061-gxv8y146	359	8	this	this	DT
cord-024061-gxv8y146	359	9	particular	particular	JJ
cord-024061-gxv8y146	359	10	route	route	NN
cord-024061-gxv8y146	359	11	as	as	IN
cord-024061-gxv8y146	359	12	significant	significant	JJ
cord-024061-gxv8y146	359	13	using	use	VBG
cord-024061-gxv8y146	359	14	both	both	CC
cord-024061-gxv8y146	359	15	the	the	DT
cord-024061-gxv8y146	359	16	HA	HA	NNP
cord-024061-gxv8y146	359	17	and	and	CC
cord-024061-gxv8y146	359	18	the	the	DT
cord-024061-gxv8y146	359	19	PB2	PB2	NNP
cord-024061-gxv8y146	359	20	segments	segment	NNS
cord-024061-gxv8y146	359	21	(	(	-LRB-
cord-024061-gxv8y146	359	22	Figures	figure	NNS
cord-024061-gxv8y146	359	23	7H	7h	CD
cord-024061-gxv8y146	359	24	,	,	,
cord-024061-gxv8y146	359	25	8D	8D	NNP
cord-024061-gxv8y146	359	26	)	)	-RRB-
cord-024061-gxv8y146	359	27	.	.	.
cord-024061-gxv8y146	360	1	Additionally	additionally	RB
cord-024061-gxv8y146	360	2	,	,	,
cord-024061-gxv8y146	360	3	Scotch	Scotch	NNP
cord-024061-gxv8y146	360	4	et	et	NNP
cord-024061-gxv8y146	360	5	al	al	NNP
cord-024061-gxv8y146	360	6	.	.	.
cord-024061-gxv8y146	361	1	(	(	-LRB-
cord-024061-gxv8y146	361	2	118	118	CD
cord-024061-gxv8y146	361	3	)	)	-RRB-
cord-024061-gxv8y146	361	4	confirmed	confirm	VBN
cord-024061-gxv8y146	361	5	agreements	agreement	NNS
cord-024061-gxv8y146	361	6	in	in	IN
cord-024061-gxv8y146	361	7	the	the	DT
cord-024061-gxv8y146	361	8	phylogeographic	phylogeographic	JJ
cord-024061-gxv8y146	361	9	inferences	inference	NNS
cord-024061-gxv8y146	361	10	between	between	IN
cord-024061-gxv8y146	361	11	HA	HA	NNP
cord-024061-gxv8y146	361	12	and	and	CC
cord-024061-gxv8y146	361	13	NA	NA	NNP
cord-024061-gxv8y146	361	14	gene	gene	NN
cord-024061-gxv8y146	361	15	segments	segment	NNS
cord-024061-gxv8y146	361	16	.	.	.
cord-024061-gxv8y146	362	1	This	this	DT
cord-024061-gxv8y146	362	2	highlights	highlight	VBZ
cord-024061-gxv8y146	362	3	another	another	DT
cord-024061-gxv8y146	362	4	decisive	decisive	JJ
cord-024061-gxv8y146	362	5	question	question	NN
cord-024061-gxv8y146	362	6	about	about	IN
cord-024061-gxv8y146	362	7	the	the	DT
cord-024061-gxv8y146	362	8	suitability	suitability	NN
cord-024061-gxv8y146	362	9	and	and	CC
cord-024061-gxv8y146	362	10	efficiency	efficiency	NN
cord-024061-gxv8y146	362	11	of	of	IN
cord-024061-gxv8y146	362	12	using	use	VBG
cord-024061-gxv8y146	362	13	single	single	JJ
cord-024061-gxv8y146	362	14	,	,	,
cord-024061-gxv8y146	362	15	multiple	multiple	JJ
cord-024061-gxv8y146	362	16	,	,	,
cord-024061-gxv8y146	362	17	or	or	CC
cord-024061-gxv8y146	362	18	whole	whole	JJ
cord-024061-gxv8y146	362	19	genome	genome	NN
cord-024061-gxv8y146	362	20	when	when	WRB
cord-024061-gxv8y146	362	21	using	use	VBG
cord-024061-gxv8y146	362	22	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	362	23	methods	method	NNS
cord-024061-gxv8y146	362	24	for	for	IN
cord-024061-gxv8y146	362	25	molecular	molecular	JJ
cord-024061-gxv8y146	362	26	surveillance	surveillance	NN
cord-024061-gxv8y146	362	27	of	of	IN
cord-024061-gxv8y146	362	28	viral	viral	JJ
cord-024061-gxv8y146	362	29	diseases	disease	NNS
cord-024061-gxv8y146	362	30	.	.	.
cord-024061-gxv8y146	363	1	Most	Most	JJS
cord-024061-gxv8y146	363	2	researchers	researcher	NNS
cord-024061-gxv8y146	363	3	advocate	advocate	VBP
cord-024061-gxv8y146	363	4	for	for	IN
cord-024061-gxv8y146	363	5	whole	whole	JJ
cord-024061-gxv8y146	363	6	-	-	HYPH
cord-024061-gxv8y146	363	7	genome	genome	NN
cord-024061-gxv8y146	363	8	analysis	analysis	NN
cord-024061-gxv8y146	363	9	by	by	IN
cord-024061-gxv8y146	363	10	either	either	CC
cord-024061-gxv8y146	363	11	analyzing	analyze	VBG
cord-024061-gxv8y146	363	12	each	each	DT
cord-024061-gxv8y146	363	13	segment	segment	NN
cord-024061-gxv8y146	363	14	alone	alone	RB
cord-024061-gxv8y146	363	15	or	or	CC
cord-024061-gxv8y146	363	16	as	as	RB
cord-024061-gxv8y146	363	17	concinnated	concinnate	VBN
cord-024061-gxv8y146	363	18	segments	segment	NNS
cord-024061-gxv8y146	363	19	.	.	.
cord-024061-gxv8y146	364	1	However	however	RB
cord-024061-gxv8y146	364	2	,	,	,
cord-024061-gxv8y146	364	3	in	in	IN
cord-024061-gxv8y146	364	4	the	the	DT
cord-024061-gxv8y146	364	5	presence	presence	NN
cord-024061-gxv8y146	364	6	of	of	IN
cord-024061-gxv8y146	364	7	a	a	DT
cord-024061-gxv8y146	364	8	large	large	JJ
cord-024061-gxv8y146	364	9	number	number	NN
cord-024061-gxv8y146	364	10	of	of	IN
cord-024061-gxv8y146	364	11	sequences	sequence	NNS
cord-024061-gxv8y146	364	12	,	,	,
cord-024061-gxv8y146	364	13	these	these	DT
cord-024061-gxv8y146	364	14	strategies	strategy	NNS
cord-024061-gxv8y146	364	15	are	be	VBP
cord-024061-gxv8y146	364	16	ill	ill	RB
cord-024061-gxv8y146	364	17	timed	time	VBN
cord-024061-gxv8y146	364	18	and	and	CC
cord-024061-gxv8y146	364	19	require	require	VB
cord-024061-gxv8y146	364	20	massive	massive	JJ
cord-024061-gxv8y146	364	21	computational	computational	JJ
cord-024061-gxv8y146	364	22	resources	resource	NNS
cord-024061-gxv8y146	364	23	,	,	,
cord-024061-gxv8y146	364	24	making	make	VBG
cord-024061-gxv8y146	364	25	them	-PRON-	PRP
cord-024061-gxv8y146	364	26	inefficient	inefficient	JJ
cord-024061-gxv8y146	364	27	for	for	IN
cord-024061-gxv8y146	364	28	targeted	targeted	JJ
cord-024061-gxv8y146	364	29	and	and	CC
cord-024061-gxv8y146	364	30	near	near	JJ
cord-024061-gxv8y146	364	31	-	-	HYPH
cord-024061-gxv8y146	364	32	realtime	realtime	NN
cord-024061-gxv8y146	364	33	surveillance	surveillance	NN
cord-024061-gxv8y146	364	34	systems	system	NNS
cord-024061-gxv8y146	364	35	.	.	.
cord-024061-gxv8y146	365	1	It	-PRON-	PRP
cord-024061-gxv8y146	365	2	is	be	VBZ
cord-024061-gxv8y146	365	3	worth	worth	JJ
cord-024061-gxv8y146	365	4	noting	note	VBG
cord-024061-gxv8y146	365	5	that	that	IN
cord-024061-gxv8y146	365	6	substitution	substitution	NN
cord-024061-gxv8y146	365	7	rate	rate	NN
cord-024061-gxv8y146	365	8	and	and	CC
cord-024061-gxv8y146	365	9	divergence	divergence	NN
cord-024061-gxv8y146	365	10	time	time	NN
cord-024061-gxv8y146	365	11	inferred	infer	VBN
cord-024061-gxv8y146	365	12	by	by	IN
cord-024061-gxv8y146	365	13	Alkhamis	Alkhamis	NNP
cord-024061-gxv8y146	365	14	et	et	NNP
cord-024061-gxv8y146	365	15	al	al	NNP
cord-024061-gxv8y146	365	16	.	.	.
cord-024061-gxv8y146	366	1	(	(	-LRB-
cord-024061-gxv8y146	366	2	43	43	CD
cord-024061-gxv8y146	366	3	)	)	-RRB-
cord-024061-gxv8y146	366	4	using	use	VBG
cord-024061-gxv8y146	366	5	the	the	DT
cord-024061-gxv8y146	366	6	FMD	FMD	NNP
cord-024061-gxv8y146	366	7	SAT1	SAT1	NNP
cord-024061-gxv8y146	366	8	VP1	vp1	NN
cord-024061-gxv8y146	366	9	segment	segment	NN
cord-024061-gxv8y146	366	10	were	be	VBD
cord-024061-gxv8y146	366	11	similar	similar	JJ
cord-024061-gxv8y146	366	12	to	to	IN
cord-024061-gxv8y146	366	13	the	the	DT
cord-024061-gxv8y146	366	14	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	366	15	estimates	estimate	NNS
cord-024061-gxv8y146	366	16	inferred	infer	VBN
cord-024061-gxv8y146	366	17	by	by	IN
cord-024061-gxv8y146	366	18	Lasecka	Lasecka	NNP
cord-024061-gxv8y146	366	19	-	-	HYPH
cord-024061-gxv8y146	366	20	Dykes	Dykes	NNP
cord-024061-gxv8y146	366	21	et	et	FW
cord-024061-gxv8y146	366	22	al	al	NNP
cord-024061-gxv8y146	366	23	.	.	.
cord-024061-gxv8y146	367	1	(	(	-LRB-
cord-024061-gxv8y146	367	2	125	125	CD
cord-024061-gxv8y146	367	3	)	)	-RRB-
cord-024061-gxv8y146	367	4	using	use	VBG
cord-024061-gxv8y146	367	5	wholegenome	wholegenome	NN
cord-024061-gxv8y146	367	6	sequences	sequence	NNS
cord-024061-gxv8y146	367	7	,	,	,
cord-024061-gxv8y146	367	8	confirming	confirm	VBG
cord-024061-gxv8y146	367	9	the	the	DT
cord-024061-gxv8y146	367	10	robustness	robustness	NN
cord-024061-gxv8y146	367	11	of	of	IN
cord-024061-gxv8y146	367	12	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	367	13	methods	method	NNS
cord-024061-gxv8y146	367	14	.	.	.
cord-024061-gxv8y146	368	1	Nevertheless	nevertheless	RB
cord-024061-gxv8y146	368	2	,	,	,
cord-024061-gxv8y146	368	3	the	the	DT
cord-024061-gxv8y146	368	4	presence	presence	NN
cord-024061-gxv8y146	368	5	of	of	IN
cord-024061-gxv8y146	368	6	recombination	recombination	NN
cord-024061-gxv8y146	368	7	events	event	NNS
cord-024061-gxv8y146	368	8	can	can	MD
cord-024061-gxv8y146	368	9	severely	severely	RB
cord-024061-gxv8y146	368	10	impact	impact	VB
cord-024061-gxv8y146	368	11	the	the	DT
cord-024061-gxv8y146	368	12	robustness	robustness	NN
cord-024061-gxv8y146	368	13	of	of	IN
cord-024061-gxv8y146	368	14	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	368	15	methods	method	NNS
cord-024061-gxv8y146	368	16	leading	lead	VBG
cord-024061-gxv8y146	368	17	to	to	IN
cord-024061-gxv8y146	368	18	inferring	infer	VBG
cord-024061-gxv8y146	368	19	biased	biased	JJ
cord-024061-gxv8y146	368	20	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	368	21	histories	history	NNS
cord-024061-gxv8y146	368	22	(	(	-LRB-
cord-024061-gxv8y146	368	23	126	126	CD
cord-024061-gxv8y146	368	24	)	)	-RRB-
cord-024061-gxv8y146	368	25	.	.	.
cord-024061-gxv8y146	369	1	Hence	hence	RB
cord-024061-gxv8y146	369	2	,	,	,
cord-024061-gxv8y146	369	3	targeting	target	VBG
cord-024061-gxv8y146	369	4	the	the	DT
cord-024061-gxv8y146	369	5	most	most	RBS
cord-024061-gxv8y146	369	6	rapidly	rapidly	RB
cord-024061-gxv8y146	369	7	evolving	evolve	VBG
cord-024061-gxv8y146	369	8	gene	gene	NN
cord-024061-gxv8y146	369	9	segment	segment	NN
cord-024061-gxv8y146	369	10	at	at	IN
cord-024061-gxv8y146	369	11	the	the	DT
cord-024061-gxv8y146	369	12	beginning	beginning	NN
cord-024061-gxv8y146	369	13	of	of	IN
cord-024061-gxv8y146	369	14	an	an	DT
cord-024061-gxv8y146	369	15	epidemic	epidemic	NN
cord-024061-gxv8y146	369	16	may	may	MD
cord-024061-gxv8y146	369	17	suffice	suffice	VB
cord-024061-gxv8y146	369	18	molecular	molecular	JJ
cord-024061-gxv8y146	369	19	surveillance	surveillance	NN
cord-024061-gxv8y146	369	20	activities	activity	NNS
cord-024061-gxv8y146	369	21	.	.	.
cord-024061-gxv8y146	370	1	That	that	DT
cord-024061-gxv8y146	370	2	said	say	VBD
cord-024061-gxv8y146	370	3	,	,	,
cord-024061-gxv8y146	370	4	the	the	DT
cord-024061-gxv8y146	370	5	choice	choice	NN
cord-024061-gxv8y146	370	6	between	between	IN
cord-024061-gxv8y146	370	7	gene	gene	NN
cord-024061-gxv8y146	370	8	segments	segment	NNS
cord-024061-gxv8y146	370	9	or	or	CC
cord-024061-gxv8y146	370	10	the	the	DT
cord-024061-gxv8y146	370	11	whole	whole	JJ
cord-024061-gxv8y146	370	12	genome	genome	NN
cord-024061-gxv8y146	370	13	should	should	MD
cord-024061-gxv8y146	370	14	depend	depend	VB
cord-024061-gxv8y146	370	15	on	on	IN
cord-024061-gxv8y146	370	16	the	the	DT
cord-024061-gxv8y146	370	17	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	370	18	properties	property	NNS
cord-024061-gxv8y146	370	19	of	of	IN
cord-024061-gxv8y146	370	20	the	the	DT
cord-024061-gxv8y146	370	21	pathogen	pathogen	NN
cord-024061-gxv8y146	370	22	,	,	,
cord-024061-gxv8y146	370	23	frequency	frequency	NN
cord-024061-gxv8y146	370	24	of	of	IN
cord-024061-gxv8y146	370	25	recombination	recombination	NN
cord-024061-gxv8y146	370	26	events	event	NNS
cord-024061-gxv8y146	370	27	,	,	,
cord-024061-gxv8y146	370	28	availability	availability	NN
cord-024061-gxv8y146	370	29	of	of	IN
cord-024061-gxv8y146	370	30	resources	resource	NNS
cord-024061-gxv8y146	370	31	,	,	,
cord-024061-gxv8y146	370	32	and	and	CC
cord-024061-gxv8y146	370	33	objectives	objective	NNS
cord-024061-gxv8y146	370	34	of	of	IN
cord-024061-gxv8y146	370	35	the	the	DT
cord-024061-gxv8y146	370	36	molecular	molecular	JJ
cord-024061-gxv8y146	370	37	surveillance	surveillance	NN
cord-024061-gxv8y146	370	38	system	system	NN
cord-024061-gxv8y146	370	39	.	.	.
cord-024061-gxv8y146	371	1	As	as	IN
cord-024061-gxv8y146	371	2	described	describe	VBN
cord-024061-gxv8y146	371	3	above	above	RB
cord-024061-gxv8y146	371	4	,	,	,
cord-024061-gxv8y146	371	5	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	371	6	inferences	inference	NNS
cord-024061-gxv8y146	371	7	tend	tend	VBP
cord-024061-gxv8y146	371	8	to	to	TO
cord-024061-gxv8y146	371	9	be	be	VB
cord-024061-gxv8y146	371	10	biased	bias	VBN
cord-024061-gxv8y146	371	11	toward	toward	IN
cord-024061-gxv8y146	371	12	the	the	DT
cord-024061-gxv8y146	371	13	available	available	JJ
cord-024061-gxv8y146	371	14	subsets	subset	NNS
cord-024061-gxv8y146	371	15	of	of	IN
cord-024061-gxv8y146	371	16	sequences	sequence	NNS
cord-024061-gxv8y146	371	17	data	datum	NNS
cord-024061-gxv8y146	371	18	.	.	.
cord-024061-gxv8y146	372	1	Hence	hence	RB
cord-024061-gxv8y146	372	2	,	,	,
cord-024061-gxv8y146	372	3	when	when	WRB
cord-024061-gxv8y146	372	4	analyzing	analyze	VBG
cord-024061-gxv8y146	372	5	novel	novel	JJ
cord-024061-gxv8y146	372	6	sequence	sequence	NN
cord-024061-gxv8y146	372	7	datasets	dataset	NNS
cord-024061-gxv8y146	372	8	,	,	,
cord-024061-gxv8y146	372	9	it	-PRON-	PRP
cord-024061-gxv8y146	372	10	is	be	VBZ
cord-024061-gxv8y146	372	11	critical	critical	JJ
cord-024061-gxv8y146	372	12	to	to	TO
cord-024061-gxv8y146	372	13	combine	combine	VB
cord-024061-gxv8y146	372	14	them	-PRON-	PRP
cord-024061-gxv8y146	372	15	with	with	IN
cord-024061-gxv8y146	372	16	genetically	genetically	RB
cord-024061-gxv8y146	372	17	related	relate	VBN
cord-024061-gxv8y146	372	18	lineages	lineage	NNS
cord-024061-gxv8y146	372	19	published	publish	VBN
cord-024061-gxv8y146	372	20	in	in	IN
cord-024061-gxv8y146	372	21	the	the	DT
cord-024061-gxv8y146	372	22	scientific	scientific	JJ
cord-024061-gxv8y146	372	23	literature	literature	NN
cord-024061-gxv8y146	372	24	or	or	CC
cord-024061-gxv8y146	372	25	publicly	publicly	RB
cord-024061-gxv8y146	372	26	available	available	JJ
cord-024061-gxv8y146	372	27	databases	database	NNS
cord-024061-gxv8y146	372	28	to	to	TO
cord-024061-gxv8y146	372	29	reduce	reduce	VB
cord-024061-gxv8y146	372	30	the	the	DT
cord-024061-gxv8y146	372	31	impact	impact	NN
cord-024061-gxv8y146	372	32	of	of	IN
cord-024061-gxv8y146	372	33	sampling	sampling	NN
cord-024061-gxv8y146	372	34	bias	bias	NN
cord-024061-gxv8y146	372	35	as	as	RB
cord-024061-gxv8y146	372	36	well	well	RB
cord-024061-gxv8y146	372	37	as	as	IN
cord-024061-gxv8y146	372	38	improve	improve	VB
cord-024061-gxv8y146	372	39	the	the	DT
cord-024061-gxv8y146	372	40	reliability	reliability	NN
cord-024061-gxv8y146	372	41	and	and	CC
cord-024061-gxv8y146	372	42	accuracy	accuracy	NN
cord-024061-gxv8y146	372	43	of	of	IN
cord-024061-gxv8y146	372	44	posterior	posterior	JJ
cord-024061-gxv8y146	372	45	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	372	46	inferences	inference	NNS
cord-024061-gxv8y146	372	47	.	.	.
cord-024061-gxv8y146	373	1	Unfortunately	unfortunately	RB
cord-024061-gxv8y146	373	2	,	,	,
cord-024061-gxv8y146	373	3	several	several	JJ
cord-024061-gxv8y146	373	4	examples	example	NNS
cord-024061-gxv8y146	373	5	published	publish	VBN
cord-024061-gxv8y146	373	6	in	in	IN
cord-024061-gxv8y146	373	7	the	the	DT
cord-024061-gxv8y146	373	8	scientific	scientific	JJ
cord-024061-gxv8y146	373	9	literature	literature	NN
cord-024061-gxv8y146	373	10	used	use	VBD
cord-024061-gxv8y146	373	11	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	373	12	methods	method	NNS
cord-024061-gxv8y146	373	13	on	on	IN
cord-024061-gxv8y146	373	14	novel	novel	JJ
cord-024061-gxv8y146	373	15	sequence	sequence	NN
cord-024061-gxv8y146	373	16	datasets	dataset	NNS
cord-024061-gxv8y146	373	17	while	while	IN
cord-024061-gxv8y146	373	18	ignoring	ignore	VBG
cord-024061-gxv8y146	373	19	their	-PRON-	PRP$
cord-024061-gxv8y146	373	20	published	publish	VBN
cord-024061-gxv8y146	373	21	relatives	relative	NNS
cord-024061-gxv8y146	373	22	(	(	-LRB-
cord-024061-gxv8y146	373	23	127	127	CD
cord-024061-gxv8y146	373	24	)	)	-RRB-
cord-024061-gxv8y146	373	25	(	(	-LRB-
cord-024061-gxv8y146	373	26	128	128	CD
cord-024061-gxv8y146	373	27	)	)	-RRB-
cord-024061-gxv8y146	373	28	(	(	-LRB-
cord-024061-gxv8y146	373	29	129	129	CD
cord-024061-gxv8y146	373	30	)	)	-RRB-
cord-024061-gxv8y146	373	31	.	.	.
cord-024061-gxv8y146	374	1	This	this	DT
cord-024061-gxv8y146	374	2	led	lead	VBD
cord-024061-gxv8y146	374	3	to	to	IN
cord-024061-gxv8y146	374	4	inferring	infer	VBG
cord-024061-gxv8y146	374	5	MCC	MCC	NNP
cord-024061-gxv8y146	374	6	trees	tree	NNS
cord-024061-gxv8y146	374	7	with	with	IN
cord-024061-gxv8y146	374	8	unaccounted	unaccounted	JJ
cord-024061-gxv8y146	374	9	phylogenetic	phylogenetic	JJ
cord-024061-gxv8y146	374	10	relationships	relationship	NNS
cord-024061-gxv8y146	374	11	such	such	JJ
cord-024061-gxv8y146	374	12	as	as	IN
cord-024061-gxv8y146	374	13	nodes	node	NNS
cord-024061-gxv8y146	374	14	,	,	,
cord-024061-gxv8y146	374	15	branches	branch	NNS
cord-024061-gxv8y146	374	16	,	,	,
cord-024061-gxv8y146	374	17	and	and	CC
cord-024061-gxv8y146	374	18	roots	root	NNS
cord-024061-gxv8y146	374	19	.	.	.
cord-024061-gxv8y146	375	1	Our	-PRON-	PRP$
cord-024061-gxv8y146	375	2	worked	work	VBN
cord-024061-gxv8y146	375	3	example	example	NN
cord-024061-gxv8y146	375	4	opens	open	VBZ
cord-024061-gxv8y146	375	5	considerations	consideration	NNS
cord-024061-gxv8y146	375	6	for	for	IN
cord-024061-gxv8y146	375	7	future	future	JJ
cord-024061-gxv8y146	375	8	work	work	NN
cord-024061-gxv8y146	375	9	involving	involve	VBG
cord-024061-gxv8y146	375	10	the	the	DT
cord-024061-gxv8y146	375	11	use	use	NN
cord-024061-gxv8y146	375	12	of	of	IN
cord-024061-gxv8y146	375	13	more	more	JJR
cord-024061-gxv8y146	375	14	complex	complex	JJ
cord-024061-gxv8y146	375	15	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	375	16	models	model	NNS
cord-024061-gxv8y146	375	17	,	,	,
cord-024061-gxv8y146	375	18	described	describe	VBN
cord-024061-gxv8y146	375	19	above	above	RB
cord-024061-gxv8y146	375	20	,	,	,
cord-024061-gxv8y146	375	21	to	to	TO
cord-024061-gxv8y146	375	22	shed	shed	VB
cord-024061-gxv8y146	375	23	deeper	deep	JJR
cord-024061-gxv8y146	375	24	insights	insight	NNS
cord-024061-gxv8y146	375	25	into	into	IN
cord-024061-gxv8y146	375	26	the	the	DT
cord-024061-gxv8y146	375	27	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	375	28	epidemiology	epidemiology	NN
cord-024061-gxv8y146	375	29	of	of	IN
cord-024061-gxv8y146	375	30	SI	SI	NNP
cord-024061-gxv8y146	375	31	.	.	.
cord-024061-gxv8y146	376	1	For	for	IN
cord-024061-gxv8y146	376	2	example	example	NN
cord-024061-gxv8y146	376	3	,	,	,
cord-024061-gxv8y146	376	4	when	when	WRB
cord-024061-gxv8y146	376	5	the	the	DT
cord-024061-gxv8y146	376	6	exact	exact	JJ
cord-024061-gxv8y146	376	7	geographical	geographical	JJ
cord-024061-gxv8y146	376	8	locations	location	NNS
cord-024061-gxv8y146	376	9	of	of	IN
cord-024061-gxv8y146	376	10	the	the	DT
cord-024061-gxv8y146	376	11	sequences	sequence	NNS
cord-024061-gxv8y146	376	12	are	be	VBP
cord-024061-gxv8y146	376	13	available	available	JJ
cord-024061-gxv8y146	376	14	,	,	,
cord-024061-gxv8y146	376	15	the	the	DT
cord-024061-gxv8y146	376	16	use	use	NN
cord-024061-gxv8y146	376	17	of	of	IN
cord-024061-gxv8y146	376	18	continuous	continuous	JJ
cord-024061-gxv8y146	376	19	phylogeographic	phylogeographic	JJ
cord-024061-gxv8y146	376	20	models	model	NNS
cord-024061-gxv8y146	376	21	will	will	MD
cord-024061-gxv8y146	376	22	enable	enable	VB
cord-024061-gxv8y146	376	23	us	-PRON-	PRP
cord-024061-gxv8y146	376	24	to	to	TO
cord-024061-gxv8y146	376	25	include	include	VB
cord-024061-gxv8y146	376	26	all	all	DT
cord-024061-gxv8y146	376	27	states	state	NNS
cord-024061-gxv8y146	376	28	in	in	IN
cord-024061-gxv8y146	376	29	the	the	DT
cord-024061-gxv8y146	376	30	analyses	analysis	NNS
cord-024061-gxv8y146	376	31	,	,	,
cord-024061-gxv8y146	376	32	including	include	VBG
cord-024061-gxv8y146	376	33	states	state	NNS
cord-024061-gxv8y146	376	34	with	with	IN
cord-024061-gxv8y146	376	35	few	few	JJ
cord-024061-gxv8y146	376	36	sequences	sequence	NNS
cord-024061-gxv8y146	376	37	.	.	.
cord-024061-gxv8y146	377	1	Besides	besides	RB
cord-024061-gxv8y146	377	2	,	,	,
cord-024061-gxv8y146	377	3	we	-PRON-	PRP
cord-024061-gxv8y146	377	4	can	can	MD
cord-024061-gxv8y146	377	5	estimate	estimate	VB
cord-024061-gxv8y146	377	6	the	the	DT
cord-024061-gxv8y146	377	7	spatiotemporal	spatiotemporal	JJ
cord-024061-gxv8y146	377	8	dispersal	dispersal	NN
cord-024061-gxv8y146	377	9	speed	speed	NN
cord-024061-gxv8y146	377	10	of	of	IN
cord-024061-gxv8y146	377	11	the	the	DT
cord-024061-gxv8y146	377	12	virus	virus	NN
cord-024061-gxv8y146	377	13	as	as	RB
cord-024061-gxv8y146	377	14	well	well	RB
cord-024061-gxv8y146	377	15	as	as	IN
cord-024061-gxv8y146	377	16	identify	identify	VB
cord-024061-gxv8y146	377	17	dispersal	dispersal	NN
cord-024061-gxv8y146	377	18	patterns	pattern	NNS
cord-024061-gxv8y146	377	19	(	(	-LRB-
cord-024061-gxv8y146	377	20	i.e.	i.e.	FW
cord-024061-gxv8y146	377	21	,	,	,
cord-024061-gxv8y146	377	22	homogeneous	homogeneous	JJ
cord-024061-gxv8y146	377	23	vs.	vs.	IN
cord-024061-gxv8y146	377	24	heterogeneous	heterogeneous	JJ
cord-024061-gxv8y146	377	25	)	)	-RRB-
cord-024061-gxv8y146	377	26	across	across	IN
cord-024061-gxv8y146	377	27	different	different	JJ
cord-024061-gxv8y146	377	28	geographical	geographical	JJ
cord-024061-gxv8y146	377	29	regions	region	NNS
cord-024061-gxv8y146	377	30	.	.	.
cord-024061-gxv8y146	378	1	Also	also	RB
cord-024061-gxv8y146	378	2	,	,	,
cord-024061-gxv8y146	378	3	the	the	DT
cord-024061-gxv8y146	378	4	use	use	NN
cord-024061-gxv8y146	378	5	of	of	IN
cord-024061-gxv8y146	378	6	GLM	GLM	NNP
cord-024061-gxv8y146	378	7	geographical	geographical	JJ
cord-024061-gxv8y146	378	8	models	model	NNS
cord-024061-gxv8y146	378	9	can	can	MD
cord-024061-gxv8y146	378	10	directly	directly	RB
cord-024061-gxv8y146	378	11	quantify	quantify	VB
cord-024061-gxv8y146	378	12	the	the	DT
cord-024061-gxv8y146	378	13	importance	importance	NN
cord-024061-gxv8y146	378	14	of	of	IN
cord-024061-gxv8y146	378	15	different	different	JJ
cord-024061-gxv8y146	378	16	environmental	environmental	JJ
cord-024061-gxv8y146	378	17	(	(	-LRB-
cord-024061-gxv8y146	378	18	e.g.	e.g.	RB
cord-024061-gxv8y146	378	19	,	,	,
cord-024061-gxv8y146	378	20	climate	climate	NN
cord-024061-gxv8y146	378	21	)	)	-RRB-
cord-024061-gxv8y146	378	22	and	and	CC
cord-024061-gxv8y146	378	23	demographical	demographical	JJ
cord-024061-gxv8y146	378	24	(	(	-LRB-
cord-024061-gxv8y146	378	25	e.g.	e.g.	RB
cord-024061-gxv8y146	378	26	,	,	,
cord-024061-gxv8y146	378	27	pig	pig	NN
cord-024061-gxv8y146	378	28	density	density	NN
cord-024061-gxv8y146	378	29	)	)	-RRB-
cord-024061-gxv8y146	378	30	factors	factor	NNS
cord-024061-gxv8y146	378	31	in	in	IN
cord-024061-gxv8y146	378	32	shaping	shape	VBG
cord-024061-gxv8y146	378	33	the	the	DT
cord-024061-gxv8y146	378	34	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	378	35	history	history	NN
cord-024061-gxv8y146	378	36	of	of	IN
cord-024061-gxv8y146	378	37	SI	SI	NNP
cord-024061-gxv8y146	378	38	in	in	IN
cord-024061-gxv8y146	378	39	the	the	DT
cord-024061-gxv8y146	378	40	United	United	NNP
cord-024061-gxv8y146	378	41	States	States	NNP
cord-024061-gxv8y146	378	42	.	.	.
cord-024061-gxv8y146	379	1	Finally	finally	RB
cord-024061-gxv8y146	379	2	,	,	,
cord-024061-gxv8y146	379	3	exploring	explore	VBG
cord-024061-gxv8y146	379	4	the	the	DT
cord-024061-gxv8y146	379	5	potentials	potential	NNS
cord-024061-gxv8y146	379	6	of	of	IN
cord-024061-gxv8y146	379	7	structured	structured	JJ
cord-024061-gxv8y146	379	8	coalescent	coalescent	NN
cord-024061-gxv8y146	379	9	models	model	NNS
cord-024061-gxv8y146	379	10	in	in	IN
cord-024061-gxv8y146	379	11	improving	improve	VBG
cord-024061-gxv8y146	379	12	the	the	DT
cord-024061-gxv8y146	379	13	reliability	reliability	NN
cord-024061-gxv8y146	379	14	of	of	IN
cord-024061-gxv8y146	379	15	inferences	inference	NNS
cord-024061-gxv8y146	379	16	derived	derive	VBN
cord-024061-gxv8y146	379	17	from	from	IN
cord-024061-gxv8y146	379	18	basic	basic	JJ
cord-024061-gxv8y146	379	19	DTAs	dta	NNS
cord-024061-gxv8y146	379	20	should	should	MD
cord-024061-gxv8y146	379	21	be	be	VB
cord-024061-gxv8y146	379	22	considered	consider	VBN
cord-024061-gxv8y146	379	23	as	as	RB
cord-024061-gxv8y146	379	24	well	well	RB
cord-024061-gxv8y146	379	25	.	.	.
cord-024061-gxv8y146	380	1	The	the	DT
cord-024061-gxv8y146	380	2	current	current	JJ
cord-024061-gxv8y146	380	3	surveillance	surveillance	NN
cord-024061-gxv8y146	380	4	programs	program	NNS
cord-024061-gxv8y146	380	5	rely	rely	VBP
cord-024061-gxv8y146	380	6	heavily	heavily	RB
cord-024061-gxv8y146	380	7	on	on	IN
cord-024061-gxv8y146	380	8	collecting	collect	VBG
cord-024061-gxv8y146	380	9	and	and	CC
cord-024061-gxv8y146	380	10	analyzing	analyze	VBG
cord-024061-gxv8y146	380	11	spatial	spatial	JJ
cord-024061-gxv8y146	380	12	,	,	,
cord-024061-gxv8y146	380	13	temporal	temporal	JJ
cord-024061-gxv8y146	380	14	,	,	,
cord-024061-gxv8y146	380	15	and	and	CC
cord-024061-gxv8y146	380	16	genomic	genomic	JJ
cord-024061-gxv8y146	380	17	aspects	aspect	NNS
cord-024061-gxv8y146	380	18	of	of	IN
cord-024061-gxv8y146	380	19	an	an	DT
cord-024061-gxv8y146	380	20	outbreak	outbreak	NN
cord-024061-gxv8y146	380	21	using	use	VBG
cord-024061-gxv8y146	380	22	classical	classical	JJ
cord-024061-gxv8y146	380	23	statistical	statistical	JJ
cord-024061-gxv8y146	380	24	methods	method	NNS
cord-024061-gxv8y146	380	25	in	in	IN
cord-024061-gxv8y146	380	26	a	a	DT
cord-024061-gxv8y146	380	27	disjointed	disjointed	JJ
cord-024061-gxv8y146	380	28	analytical	analytical	JJ
cord-024061-gxv8y146	380	29	framework	framework	NN
cord-024061-gxv8y146	380	30	.	.	.
cord-024061-gxv8y146	381	1	This	this	DT
cord-024061-gxv8y146	381	2	disjointed	disjointed	JJ
cord-024061-gxv8y146	381	3	framework	framework	NN
cord-024061-gxv8y146	381	4	suffers	suffer	VBZ
cord-024061-gxv8y146	381	5	from	from	IN
cord-024061-gxv8y146	381	6	many	many	JJ
cord-024061-gxv8y146	381	7	biases	bias	NNS
cord-024061-gxv8y146	381	8	and	and	CC
cord-024061-gxv8y146	381	9	is	be	VBZ
cord-024061-gxv8y146	381	10	not	not	RB
cord-024061-gxv8y146	381	11	capable	capable	JJ
cord-024061-gxv8y146	381	12	of	of	IN
cord-024061-gxv8y146	381	13	answering	answer	VBG
cord-024061-gxv8y146	381	14	more	more	RBR
cord-024061-gxv8y146	381	15	profound	profound	JJ
cord-024061-gxv8y146	381	16	epidemiological	epidemiological	JJ
cord-024061-gxv8y146	381	17	questions	question	NNS
cord-024061-gxv8y146	381	18	about	about	IN
cord-024061-gxv8y146	381	19	the	the	DT
cord-024061-gxv8y146	381	20	outbreak	outbreak	NN
cord-024061-gxv8y146	381	21	of	of	IN
cord-024061-gxv8y146	381	22	current	current	JJ
cord-024061-gxv8y146	381	23	dynamics	dynamic	NNS
cord-024061-gxv8y146	381	24	.	.	.
cord-024061-gxv8y146	382	1	Using	use	VBG
cord-024061-gxv8y146	382	2	our	-PRON-	PRP$
cord-024061-gxv8y146	382	3	suggested	suggest	VBN
cord-024061-gxv8y146	382	4	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	382	5	analytical	analytical	JJ
cord-024061-gxv8y146	382	6	pipeline	pipeline	NN
cord-024061-gxv8y146	382	7	,	,	,
cord-024061-gxv8y146	382	8	we	-PRON-	PRP
cord-024061-gxv8y146	382	9	were	be	VBD
cord-024061-gxv8y146	382	10	able	able	JJ
cord-024061-gxv8y146	382	11	to	to	TO
cord-024061-gxv8y146	382	12	fulfill	fulfill	VB
cord-024061-gxv8y146	382	13	critical	critical	JJ
cord-024061-gxv8y146	382	14	epidemiological	epidemiological	JJ
cord-024061-gxv8y146	382	15	questions	question	NNS
cord-024061-gxv8y146	382	16	about	about	IN
cord-024061-gxv8y146	382	17	the	the	DT
cord-024061-gxv8y146	382	18	emergence	emergence	NN
cord-024061-gxv8y146	382	19	and	and	CC
cord-024061-gxv8y146	382	20	evolution	evolution	NN
cord-024061-gxv8y146	382	21	of	of	IN
cord-024061-gxv8y146	382	22	currently	currently	RB
cord-024061-gxv8y146	382	23	circulating	circulate	VBG
cord-024061-gxv8y146	382	24	humanlike	humanlike	JJ
cord-024061-gxv8y146	382	25	H3	H3	NNP
cord-024061-gxv8y146	382	26	SI	SI	NNP
cord-024061-gxv8y146	382	27	viruses	virus	NNS
cord-024061-gxv8y146	382	28	in	in	IN
cord-024061-gxv8y146	382	29	the	the	DT
cord-024061-gxv8y146	382	30	United	United	NNP
cord-024061-gxv8y146	382	31	States	States	NNP
cord-024061-gxv8y146	382	32	,	,	,
cord-024061-gxv8y146	382	33	with	with	IN
cord-024061-gxv8y146	382	34	the	the	DT
cord-024061-gxv8y146	382	35	primary	primary	JJ
cord-024061-gxv8y146	382	36	goal	goal	NN
cord-024061-gxv8y146	382	37	of	of	IN
cord-024061-gxv8y146	382	38	guiding	guide	VBG
cord-024061-gxv8y146	382	39	risk	risk	NN
cord-024061-gxv8y146	382	40	-	-	HYPH
cord-024061-gxv8y146	382	41	based	base	VBN
cord-024061-gxv8y146	382	42	surveillance	surveillance	NN
cord-024061-gxv8y146	382	43	resources	resource	NNS
cord-024061-gxv8y146	382	44	.	.	.
cord-024061-gxv8y146	383	1	For	for	IN
cord-024061-gxv8y146	383	2	example	example	NN
cord-024061-gxv8y146	383	3	,	,	,
cord-024061-gxv8y146	383	4	using	use	VBG
cord-024061-gxv8y146	383	5	inferences	inference	NNS
cord-024061-gxv8y146	383	6	from	from	IN
cord-024061-gxv8y146	383	7	the	the	DT
cord-024061-gxv8y146	383	8	HA	HA	NNP
cord-024061-gxv8y146	383	9	segment	segment	NN
cord-024061-gxv8y146	383	10	,	,	,
cord-024061-gxv8y146	383	11	we	-PRON-	PRP
cord-024061-gxv8y146	383	12	were	be	VBD
cord-024061-gxv8y146	383	13	able	able	JJ
cord-024061-gxv8y146	383	14	to	to	TO
cord-024061-gxv8y146	383	15	identify	identify	VB
cord-024061-gxv8y146	383	16	the	the	DT
cord-024061-gxv8y146	383	17	dates	date	NNS
cord-024061-gxv8y146	383	18	of	of	IN
cord-024061-gxv8y146	383	19	epidemic	epidemic	NN
cord-024061-gxv8y146	383	20	introduction	introduction	NN
cord-024061-gxv8y146	383	21	to	to	IN
cord-024061-gxv8y146	383	22	each	each	DT
cord-024061-gxv8y146	383	23	state	state	NN
cord-024061-gxv8y146	383	24	.	.	.
cord-024061-gxv8y146	384	1	Also	also	RB
cord-024061-gxv8y146	384	2	,	,	,
cord-024061-gxv8y146	384	3	we	-PRON-	PRP
cord-024061-gxv8y146	384	4	were	be	VBD
cord-024061-gxv8y146	384	5	able	able	JJ
cord-024061-gxv8y146	384	6	to	to	TO
cord-024061-gxv8y146	384	7	identify	identify	VB
cord-024061-gxv8y146	384	8	the	the	DT
cord-024061-gxv8y146	384	9	geographic	geographic	JJ
cord-024061-gxv8y146	384	10	origins	origin	NNS
cord-024061-gxv8y146	384	11	of	of	IN
cord-024061-gxv8y146	384	12	the	the	DT
cord-024061-gxv8y146	384	13	current	current	JJ
cord-024061-gxv8y146	384	14	outbreaks	outbreak	NNS
cord-024061-gxv8y146	384	15	and	and	CC
cord-024061-gxv8y146	384	16	observed	observe	VBD
cord-024061-gxv8y146	384	17	their	-PRON-	PRP$
cord-024061-gxv8y146	384	18	genomic	genomic	JJ
cord-024061-gxv8y146	384	19	-	-	HYPH
cord-024061-gxv8y146	384	20	spatio	spatio	JJ
cord-024061-gxv8y146	384	21	-	-	HYPH
cord-024061-gxv8y146	384	22	temporal	temporal	JJ
cord-024061-gxv8y146	384	23	diffusion	diffusion	NN
cord-024061-gxv8y146	384	24	process	process	NN
cord-024061-gxv8y146	384	25	through	through	IN
cord-024061-gxv8y146	384	26	time	time	NN
cord-024061-gxv8y146	384	27	between	between	IN
cord-024061-gxv8y146	384	28	states	state	NNS
cord-024061-gxv8y146	384	29	.	.	.
cord-024061-gxv8y146	385	1	Also	also	RB
cord-024061-gxv8y146	385	2	,	,	,
cord-024061-gxv8y146	385	3	we	-PRON-	PRP
cord-024061-gxv8y146	385	4	identified	identify	VBD
cord-024061-gxv8y146	385	5	highrisk	highrisk	JJ
cord-024061-gxv8y146	385	6	viral	viral	JJ
cord-024061-gxv8y146	385	7	dispersal	dispersal	NN
cord-024061-gxv8y146	385	8	routes	route	NNS
cord-024061-gxv8y146	385	9	between	between	IN
cord-024061-gxv8y146	385	10	states	state	NNS
cord-024061-gxv8y146	385	11	,	,	,
cord-024061-gxv8y146	385	12	rank	rank	NN
cord-024061-gxv8y146	385	13	-	-	HYPH
cord-024061-gxv8y146	385	14	ordered	order	VBN
cord-024061-gxv8y146	385	15	their	-PRON-	PRP$
cord-024061-gxv8y146	385	16	significance	significance	NN
cord-024061-gxv8y146	385	17	,	,	,
cord-024061-gxv8y146	385	18	and	and	CC
cord-024061-gxv8y146	385	19	defined	define	VBD
cord-024061-gxv8y146	385	20	their	-PRON-	PRP$
cord-024061-gxv8y146	385	21	directions	direction	NNS
cord-024061-gxv8y146	385	22	.	.	.
cord-024061-gxv8y146	386	1	All	all	DT
cord-024061-gxv8y146	386	2	of	of	IN
cord-024061-gxv8y146	386	3	these	these	DT
cord-024061-gxv8y146	386	4	are	be	VBP
cord-024061-gxv8y146	386	5	integral	integral	JJ
cord-024061-gxv8y146	386	6	components	component	NNS
cord-024061-gxv8y146	386	7	of	of	IN
cord-024061-gxv8y146	386	8	an	an	DT
cord-024061-gxv8y146	386	9	effective	effective	JJ
cord-024061-gxv8y146	386	10	risk	risk	NN
cord-024061-gxv8y146	386	11	-	-	HYPH
cord-024061-gxv8y146	386	12	based	base	VBN
cord-024061-gxv8y146	386	13	molecular	molecular	JJ
cord-024061-gxv8y146	386	14	surveillance	surveillance	NN
cord-024061-gxv8y146	386	15	program	program	NN
cord-024061-gxv8y146	386	16	,	,	,
cord-024061-gxv8y146	386	17	and	and	CC
cord-024061-gxv8y146	386	18	the	the	DT
cord-024061-gxv8y146	386	19	ability	ability	NN
cord-024061-gxv8y146	386	20	to	to	TO
cord-024061-gxv8y146	386	21	achieve	achieve	VB
cord-024061-gxv8y146	386	22	in	in	IN
cord-024061-gxv8y146	386	23	real	real	JJ
cord-024061-gxv8y146	386	24	time	time	NN
cord-024061-gxv8y146	386	25	is	be	VBZ
cord-024061-gxv8y146	386	26	the	the	DT
cord-024061-gxv8y146	386	27	future	future	JJ
cord-024061-gxv8y146	386	28	molecular	molecular	JJ
cord-024061-gxv8y146	386	29	surveillance	surveillance	NN
cord-024061-gxv8y146	386	30	of	of	IN
cord-024061-gxv8y146	386	31	animal	animal	NN
cord-024061-gxv8y146	386	32	diseases	disease	NNS
cord-024061-gxv8y146	386	33	.	.	.
cord-024061-gxv8y146	387	1	Nevertheless	nevertheless	RB
cord-024061-gxv8y146	387	2	,	,	,
cord-024061-gxv8y146	387	3	the	the	DT
cord-024061-gxv8y146	387	4	availability	availability	NN
cord-024061-gxv8y146	387	5	of	of	IN
cord-024061-gxv8y146	387	6	computational	computational	JJ
cord-024061-gxv8y146	387	7	resources	resource	NNS
cord-024061-gxv8y146	387	8	for	for	IN
cord-024061-gxv8y146	387	9	designing	design	VBG
cord-024061-gxv8y146	387	10	an	an	DT
cord-024061-gxv8y146	387	11	ongoing	ongoing	JJ
cord-024061-gxv8y146	387	12	phylodynamic	phylodynamic	NN
cord-024061-gxv8y146	387	13	-	-	HYPH
cord-024061-gxv8y146	387	14	based	base	VBN
cord-024061-gxv8y146	387	15	molecular	molecular	JJ
cord-024061-gxv8y146	387	16	surveillance	surveillance	NN
cord-024061-gxv8y146	387	17	system	system	NN
cord-024061-gxv8y146	387	18	will	will	MD
cord-024061-gxv8y146	387	19	always	always	RB
cord-024061-gxv8y146	387	20	remain	remain	VB
cord-024061-gxv8y146	387	21	a	a	DT
cord-024061-gxv8y146	387	22	challenge	challenge	NN
cord-024061-gxv8y146	387	23	,	,	,
cord-024061-gxv8y146	387	24	especially	especially	RB
cord-024061-gxv8y146	387	25	for	for	IN
cord-024061-gxv8y146	387	26	developing	develop	VBG
cord-024061-gxv8y146	387	27	countries	country	NNS
cord-024061-gxv8y146	387	28	.	.	.
cord-024061-gxv8y146	388	1	That	that	DT
cord-024061-gxv8y146	388	2	said	say	VBD
cord-024061-gxv8y146	388	3	,	,	,
cord-024061-gxv8y146	388	4	a	a	DT
cord-024061-gxv8y146	388	5	few	few	JJ
cord-024061-gxv8y146	388	6	open	open	JJ
cord-024061-gxv8y146	388	7	-	-	HYPH
cord-024061-gxv8y146	388	8	source	source	NN
cord-024061-gxv8y146	388	9	software	software	NN
cord-024061-gxv8y146	388	10	developed	develop	VBN
cord-024061-gxv8y146	388	11	recently	recently	RB
cord-024061-gxv8y146	388	12	can	can	MD
cord-024061-gxv8y146	388	13	perform	perform	VB
cord-024061-gxv8y146	388	14	basic	basic	JJ
cord-024061-gxv8y146	388	15	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	388	16	analysis	analysis	NN
cord-024061-gxv8y146	388	17	(	(	-LRB-
cord-024061-gxv8y146	388	18	e.g.	e.g.	RB
cord-024061-gxv8y146	388	19	,	,	,
cord-024061-gxv8y146	388	20	estimate	estimate	VBP
cord-024061-gxv8y146	388	21	molecular	molecular	JJ
cord-024061-gxv8y146	388	22	clocks	clock	NNS
cord-024061-gxv8y146	388	23	and	and	CC
cord-024061-gxv8y146	388	24	infer	infer	VB
cord-024061-gxv8y146	388	25	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	388	26	models	model	NNS
cord-024061-gxv8y146	388	27	)	)	-RRB-
cord-024061-gxv8y146	388	28	using	use	VBG
cord-024061-gxv8y146	388	29	an	an	DT
cord-024061-gxv8y146	388	30	ML	ML	NNP
cord-024061-gxv8y146	388	31	statistical	statistical	JJ
cord-024061-gxv8y146	388	32	framework	framework	NN
cord-024061-gxv8y146	388	33	,	,	,
cord-024061-gxv8y146	388	34	including	include	VBG
cord-024061-gxv8y146	388	35	TimeTree	TimeTree	NNP
cord-024061-gxv8y146	388	36	(	(	-LRB-
cord-024061-gxv8y146	388	37	130	130	CD
cord-024061-gxv8y146	388	38	)	)	-RRB-
cord-024061-gxv8y146	388	39	,	,	,
cord-024061-gxv8y146	388	40	treedater	treedater	NNP
cord-024061-gxv8y146	388	41	R	r	NN
cord-024061-gxv8y146	388	42	package	package	NN
cord-024061-gxv8y146	388	43	(	(	-LRB-
cord-024061-gxv8y146	388	44	131	131	CD
cord-024061-gxv8y146	388	45	)	)	-RRB-
cord-024061-gxv8y146	388	46	,	,	,
cord-024061-gxv8y146	388	47	and	and	CC
cord-024061-gxv8y146	388	48	Least	Least	JJS
cord-024061-gxv8y146	388	49	Square	Square	NNP
cord-024061-gxv8y146	388	50	Dating	Dating	NNP
cord-024061-gxv8y146	388	51	(	(	-LRB-
cord-024061-gxv8y146	388	52	120	120	CD
cord-024061-gxv8y146	388	53	)	)	-RRB-
cord-024061-gxv8y146	388	54	.	.	.
cord-024061-gxv8y146	389	1	While	while	IN
cord-024061-gxv8y146	389	2	the	the	DT
cord-024061-gxv8y146	389	3	algorithms	algorithm	NNS
cord-024061-gxv8y146	389	4	implemented	implement	VBN
cord-024061-gxv8y146	389	5	in	in	IN
cord-024061-gxv8y146	389	6	these	these	DT
cord-024061-gxv8y146	389	7	software	software	NN
cord-024061-gxv8y146	389	8	trades	trade	NNS
cord-024061-gxv8y146	389	9	off	off	IN
cord-024061-gxv8y146	389	10	the	the	DT
cord-024061-gxv8y146	389	11	advantages	advantage	NNS
cord-024061-gxv8y146	389	12	of	of	IN
cord-024061-gxv8y146	389	13	the	the	DT
cord-024061-gxv8y146	389	14	Bayesian	bayesian	JJ
cord-024061-gxv8y146	389	15	framework	framework	NN
cord-024061-gxv8y146	389	16	,	,	,
cord-024061-gxv8y146	389	17	in	in	IN
cord-024061-gxv8y146	389	18	the	the	DT
cord-024061-gxv8y146	389	19	presence	presence	NN
cord-024061-gxv8y146	389	20	of	of	IN
cord-024061-gxv8y146	389	21	large	large	JJ
cord-024061-gxv8y146	389	22	sequence	sequence	NN
cord-024061-gxv8y146	389	23	datasets	dataset	NNS
cord-024061-gxv8y146	389	24	,	,	,
cord-024061-gxv8y146	389	25	they	-PRON-	PRP
cord-024061-gxv8y146	389	26	can	can	MD
cord-024061-gxv8y146	389	27	produce	produce	VB
cord-024061-gxv8y146	389	28	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	389	29	estimates	estimate	NNS
cord-024061-gxv8y146	389	30	similar	similar	JJ
cord-024061-gxv8y146	389	31	to	to	IN
cord-024061-gxv8y146	389	32	those	those	DT
cord-024061-gxv8y146	389	33	estimated	estimate	VBN
cord-024061-gxv8y146	389	34	by	by	IN
cord-024061-gxv8y146	389	35	BEAST	BEAST	NNP
cord-024061-gxv8y146	389	36	using	use	VBG
cord-024061-gxv8y146	389	37	substantially	substantially	RB
cord-024061-gxv8y146	389	38	less	less	JJR
cord-024061-gxv8y146	389	39	computational	computational	JJ
cord-024061-gxv8y146	389	40	resources	resource	NNS
cord-024061-gxv8y146	389	41	(	(	-LRB-
cord-024061-gxv8y146	389	42	120	120	CD
cord-024061-gxv8y146	389	43	,	,	,
cord-024061-gxv8y146	389	44	130	130	CD
cord-024061-gxv8y146	389	45	,	,	,
cord-024061-gxv8y146	389	46	131	131	CD
cord-024061-gxv8y146	389	47	)	)	-RRB-
cord-024061-gxv8y146	389	48	.	.	.
cord-024061-gxv8y146	390	1	Nextstrain	Nextstrain	NNP
cord-024061-gxv8y146	390	2	(	(	-LRB-
cord-024061-gxv8y146	390	3	https://nextstrain.org	https://nextstrain.org	NNP
cord-024061-gxv8y146	390	4	)	)	-RRB-
cord-024061-gxv8y146	390	5	,	,	,
cord-024061-gxv8y146	390	6	which	which	WDT
cord-024061-gxv8y146	390	7	implements	implement	VBZ
cord-024061-gxv8y146	390	8	TreeTime	TreeTime	NNP
cord-024061-gxv8y146	390	9	is	be	VBZ
cord-024061-gxv8y146	390	10	a	a	DT
cord-024061-gxv8y146	390	11	futuristic	futuristic	JJ
cord-024061-gxv8y146	390	12	working	work	VBG
cord-024061-gxv8y146	390	13	example	example	NN
cord-024061-gxv8y146	390	14	of	of	IN
cord-024061-gxv8y146	390	15	a	a	DT
cord-024061-gxv8y146	390	16	web	web	NN
cord-024061-gxv8y146	390	17	-	-	HYPH
cord-024061-gxv8y146	390	18	based	base	VBN
cord-024061-gxv8y146	390	19	real	real	JJ
cord-024061-gxv8y146	390	20	-	-	HYPH
cord-024061-gxv8y146	390	21	time	time	NN
cord-024061-gxv8y146	390	22	molecular	molecular	JJ
cord-024061-gxv8y146	390	23	surveillance	surveillance	NN
cord-024061-gxv8y146	390	24	system	system	NN
cord-024061-gxv8y146	390	25	for	for	IN
cord-024061-gxv8y146	390	26	important	important	JJ
cord-024061-gxv8y146	390	27	human	human	JJ
cord-024061-gxv8y146	390	28	pathogens	pathogen	NNS
cord-024061-gxv8y146	390	29	such	such	JJ
cord-024061-gxv8y146	390	30	as	as	IN
cord-024061-gxv8y146	390	31	influenza	influenza	NN
cord-024061-gxv8y146	390	32	,	,	,
cord-024061-gxv8y146	390	33	Ebola	Ebola	NNP
cord-024061-gxv8y146	390	34	,	,	,
cord-024061-gxv8y146	390	35	Dengue	Dengue	NNP
cord-024061-gxv8y146	390	36	,	,	,
cord-024061-gxv8y146	390	37	and	and	CC
cord-024061-gxv8y146	390	38	the	the	DT
cord-024061-gxv8y146	390	39	newly	newly	RB
cord-024061-gxv8y146	390	40	emerging	emerge	VBG
cord-024061-gxv8y146	390	41	corona	corona	NN
cord-024061-gxv8y146	390	42	viruses	virus	NNS
cord-024061-gxv8y146	390	43	.	.	.
cord-024061-gxv8y146	391	1	This	this	DT
cord-024061-gxv8y146	391	2	surveillance	surveillance	NN
cord-024061-gxv8y146	391	3	system	system	NN
cord-024061-gxv8y146	391	4	has	have	VBZ
cord-024061-gxv8y146	391	5	an	an	DT
cord-024061-gxv8y146	391	6	on	on	IN
cord-024061-gxv8y146	391	7	-	-	HYPH
cord-024061-gxv8y146	391	8	going	go	VBG
cord-024061-gxv8y146	391	9	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	391	10	analytical	analytical	JJ
cord-024061-gxv8y146	391	11	engine	engine	NN
cord-024061-gxv8y146	391	12	that	that	WDT
cord-024061-gxv8y146	391	13	traces	trace	VBZ
cord-024061-gxv8y146	391	14	,	,	,
cord-024061-gxv8y146	391	15	in	in	IN
cord-024061-gxv8y146	391	16	real	real	JJ
cord-024061-gxv8y146	391	17	-	-	HYPH
cord-024061-gxv8y146	391	18	time	time	NN
cord-024061-gxv8y146	391	19	genetic	genetic	JJ
cord-024061-gxv8y146	391	20	diversity	diversity	NN
cord-024061-gxv8y146	391	21	,	,	,
cord-024061-gxv8y146	391	22	divergence	divergence	NN
cord-024061-gxv8y146	391	23	times	time	NNS
cord-024061-gxv8y146	391	24	,	,	,
cord-024061-gxv8y146	391	25	geographical	geographical	JJ
cord-024061-gxv8y146	391	26	origins	origin	NNS
cord-024061-gxv8y146	391	27	,	,	,
cord-024061-gxv8y146	391	28	and	and	CC
cord-024061-gxv8y146	391	29	dispersal	dispersal	NN
cord-024061-gxv8y146	391	30	on	on	IN
cord-024061-gxv8y146	391	31	global	global	JJ
cord-024061-gxv8y146	391	32	scales	scale	NNS
cord-024061-gxv8y146	391	33	.	.	.
cord-024061-gxv8y146	392	1	The	the	DT
cord-024061-gxv8y146	392	2	system	system	NN
cord-024061-gxv8y146	392	3	updates	update	VBZ
cord-024061-gxv8y146	392	4	the	the	DT
cord-024061-gxv8y146	392	5	results	result	NNS
cord-024061-gxv8y146	392	6	of	of	IN
cord-024061-gxv8y146	392	7	the	the	DT
cord-024061-gxv8y146	392	8	MCC	MCC	NNP
cord-024061-gxv8y146	392	9	tree	tree	NN
cord-024061-gxv8y146	392	10	once	once	IN
cord-024061-gxv8y146	392	11	new	new	JJ
cord-024061-gxv8y146	392	12	sequences	sequence	NNS
cord-024061-gxv8y146	392	13	are	be	VBP
cord-024061-gxv8y146	392	14	deposited	deposit	VBN
cord-024061-gxv8y146	392	15	in	in	IN
cord-024061-gxv8y146	392	16	other	other	JJ
cord-024061-gxv8y146	392	17	web	web	NN
cord-024061-gxv8y146	392	18	-	-	HYPH
cord-024061-gxv8y146	392	19	based	base	VBN
cord-024061-gxv8y146	392	20	publicly	publicly	RB
cord-024061-gxv8y146	392	21	available	available	JJ
cord-024061-gxv8y146	392	22	genomic	genomic	JJ
cord-024061-gxv8y146	392	23	databases	database	NNS
cord-024061-gxv8y146	392	24	.	.	.
cord-024061-gxv8y146	393	1	However	however	RB
cord-024061-gxv8y146	393	2	,	,	,
cord-024061-gxv8y146	393	3	this	this	DT
cord-024061-gxv8y146	393	4	project	project	NN
cord-024061-gxv8y146	393	5	is	be	VBZ
cord-024061-gxv8y146	393	6	achieved	achieve	VBN
cord-024061-gxv8y146	393	7	through	through	IN
cord-024061-gxv8y146	393	8	rigorous	rigorous	JJ
cord-024061-gxv8y146	393	9	and	and	CC
cord-024061-gxv8y146	393	10	consistent	consistent	JJ
cord-024061-gxv8y146	393	11	global	global	JJ
cord-024061-gxv8y146	393	12	collaboration	collaboration	NN
cord-024061-gxv8y146	393	13	and	and	CC
cord-024061-gxv8y146	393	14	data	datum	NNS
cord-024061-gxv8y146	393	15	sharing	sharing	NN
cord-024061-gxv8y146	393	16	.	.	.
cord-024061-gxv8y146	394	1	In	in	IN
cord-024061-gxv8y146	394	2	the	the	DT
cord-024061-gxv8y146	394	3	United	United	NNP
cord-024061-gxv8y146	394	4	States	States	NNP
cord-024061-gxv8y146	394	5	,	,	,
cord-024061-gxv8y146	394	6	resources	resource	NNS
cord-024061-gxv8y146	394	7	for	for	IN
cord-024061-gxv8y146	394	8	developing	develop	VBG
cord-024061-gxv8y146	394	9	a	a	DT
cord-024061-gxv8y146	394	10	similar	similar	JJ
cord-024061-gxv8y146	394	11	system	system	NN
cord-024061-gxv8y146	394	12	for	for	IN
cord-024061-gxv8y146	394	13	tracing	trace	VBG
cord-024061-gxv8y146	394	14	animal	animal	NN
cord-024061-gxv8y146	394	15	diseases	disease	NNS
cord-024061-gxv8y146	394	16	are	be	VBP
cord-024061-gxv8y146	394	17	readily	readily	RB
cord-024061-gxv8y146	394	18	available	available	JJ
cord-024061-gxv8y146	394	19	.	.	.
cord-024061-gxv8y146	395	1	Nevertheless	nevertheless	RB
cord-024061-gxv8y146	395	2	,	,	,
cord-024061-gxv8y146	395	3	the	the	DT
cord-024061-gxv8y146	395	4	chain	chain	NN
cord-024061-gxv8y146	395	5	of	of	IN
cord-024061-gxv8y146	395	6	collaboration	collaboration	NN
cord-024061-gxv8y146	395	7	between	between	IN
cord-024061-gxv8y146	395	8	researchers	researcher	NNS
cord-024061-gxv8y146	395	9	,	,	,
cord-024061-gxv8y146	395	10	government	government	NN
cord-024061-gxv8y146	395	11	,	,	,
cord-024061-gxv8y146	395	12	and	and	CC
cord-024061-gxv8y146	395	13	producers	producer	NNS
cord-024061-gxv8y146	395	14	in	in	IN
cord-024061-gxv8y146	395	15	the	the	DT
cord-024061-gxv8y146	395	16	animal	animal	NN
cord-024061-gxv8y146	395	17	sector	sector	NN
cord-024061-gxv8y146	395	18	is	be	VBZ
cord-024061-gxv8y146	395	19	hard	hard	JJ
cord-024061-gxv8y146	395	20	to	to	TO
cord-024061-gxv8y146	395	21	maintain	maintain	VB
cord-024061-gxv8y146	395	22	due	due	IN
cord-024061-gxv8y146	395	23	to	to	IN
cord-024061-gxv8y146	395	24	logistic	logistic	JJ
cord-024061-gxv8y146	395	25	,	,	,
cord-024061-gxv8y146	395	26	economic	economic	JJ
cord-024061-gxv8y146	395	27	,	,	,
cord-024061-gxv8y146	395	28	and	and	CC
cord-024061-gxv8y146	395	29	educational	educational	JJ
cord-024061-gxv8y146	395	30	(	(	-LRB-
cord-024061-gxv8y146	395	31	i.e.	i.e.	FW
cord-024061-gxv8y146	395	32	,	,	,
cord-024061-gxv8y146	395	33	lack	lack	NN
cord-024061-gxv8y146	395	34	of	of	IN
cord-024061-gxv8y146	395	35	awareness	awareness	NN
cord-024061-gxv8y146	395	36	and	and	CC
cord-024061-gxv8y146	395	37	skill	skill	NN
cord-024061-gxv8y146	395	38	in	in	IN
cord-024061-gxv8y146	395	39	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	395	40	methods	method	NNS
cord-024061-gxv8y146	395	41	)	)	-RRB-
cord-024061-gxv8y146	395	42	reasons	reason	NNS
cord-024061-gxv8y146	395	43	.	.	.
cord-024061-gxv8y146	396	1	Nevertheless	nevertheless	RB
cord-024061-gxv8y146	396	2	,	,	,
cord-024061-gxv8y146	396	3	recent	recent	JJ
cord-024061-gxv8y146	396	4	scientific	scientific	JJ
cord-024061-gxv8y146	396	5	literature	literature	NN
cord-024061-gxv8y146	396	6	on	on	IN
cord-024061-gxv8y146	396	7	the	the	DT
cord-024061-gxv8y146	396	8	use	use	NN
cord-024061-gxv8y146	396	9	of	of	IN
cord-024061-gxv8y146	396	10	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	396	11	methods	method	NNS
cord-024061-gxv8y146	396	12	for	for	IN
cord-024061-gxv8y146	396	13	animal	animal	NN
cord-024061-gxv8y146	396	14	disease	disease	NN
cord-024061-gxv8y146	396	15	surveillance	surveillance	NN
cord-024061-gxv8y146	396	16	is	be	VBZ
cord-024061-gxv8y146	396	17	notably	notably	RB
cord-024061-gxv8y146	396	18	growing	grow	VBG
cord-024061-gxv8y146	396	19	,	,	,
cord-024061-gxv8y146	396	20	which	which	WDT
cord-024061-gxv8y146	396	21	reflects	reflect	VBZ
cord-024061-gxv8y146	396	22	the	the	DT
cord-024061-gxv8y146	396	23	increased	increase	VBN
cord-024061-gxv8y146	396	24	awareness	awareness	NN
cord-024061-gxv8y146	396	25	between	between	IN
cord-024061-gxv8y146	396	26	veterinarians	veterinarian	NNS
cord-024061-gxv8y146	396	27	about	about	IN
cord-024061-gxv8y146	396	28	the	the	DT
cord-024061-gxv8y146	396	29	capacities	capacity	NNS
cord-024061-gxv8y146	396	30	of	of	IN
cord-024061-gxv8y146	396	31	such	such	JJ
cord-024061-gxv8y146	396	32	methods	method	NNS
cord-024061-gxv8y146	396	33	and	and	CC
cord-024061-gxv8y146	396	34	the	the	DT
cord-024061-gxv8y146	396	35	goodwill	goodwill	NN
cord-024061-gxv8y146	396	36	of	of	IN
cord-024061-gxv8y146	396	37	the	the	DT
cord-024061-gxv8y146	396	38	industry	industry	NN
cord-024061-gxv8y146	396	39	leaders	leader	NNS
cord-024061-gxv8y146	396	40	to	to	TO
cord-024061-gxv8y146	396	41	voluntarily	voluntarily	RB
cord-024061-gxv8y146	396	42	share	share	VB
cord-024061-gxv8y146	396	43	their	-PRON-	PRP$
cord-024061-gxv8y146	396	44	data	datum	NNS
cord-024061-gxv8y146	396	45	(	(	-LRB-
cord-024061-gxv8y146	396	46	37	37	CD
cord-024061-gxv8y146	396	47	,	,	,
cord-024061-gxv8y146	396	48	132	132	CD
cord-024061-gxv8y146	396	49	)	)	-RRB-
cord-024061-gxv8y146	396	50	.	.	.
cord-024061-gxv8y146	397	1	Therefore	therefore	RB
cord-024061-gxv8y146	397	2	,	,	,
cord-024061-gxv8y146	397	3	we	-PRON-	PRP
cord-024061-gxv8y146	397	4	anticipate	anticipate	VBP
cord-024061-gxv8y146	397	5	a	a	DT
cord-024061-gxv8y146	397	6	new	new	JJ
cord-024061-gxv8y146	397	7	era	era	NN
cord-024061-gxv8y146	397	8	of	of	IN
cord-024061-gxv8y146	397	9	animal	animal	NN
cord-024061-gxv8y146	397	10	disease	disease	NN
cord-024061-gxv8y146	397	11	prevention	prevention	NN
cord-024061-gxv8y146	397	12	and	and	CC
cord-024061-gxv8y146	397	13	control	control	NN
cord-024061-gxv8y146	397	14	in	in	IN
cord-024061-gxv8y146	397	15	the	the	DT
cord-024061-gxv8y146	397	16	United	United	NNP
cord-024061-gxv8y146	397	17	States	States	NNP
cord-024061-gxv8y146	397	18	.	.	.
cord-024061-gxv8y146	398	1	In	in	IN
cord-024061-gxv8y146	398	2	contrast	contrast	NN
cord-024061-gxv8y146	398	3	,	,	,
cord-024061-gxv8y146	398	4	veterinary	veterinary	JJ
cord-024061-gxv8y146	398	5	infrastructure	infrastructure	NN
cord-024061-gxv8y146	398	6	in	in	IN
cord-024061-gxv8y146	398	7	developing	develop	VBG
cord-024061-gxv8y146	398	8	countries	country	NNS
cord-024061-gxv8y146	398	9	is	be	VBZ
cord-024061-gxv8y146	398	10	severely	severely	RB
cord-024061-gxv8y146	398	11	lacking	lack	VBG
cord-024061-gxv8y146	398	12	,	,	,
cord-024061-gxv8y146	398	13	in	in	IN
cord-024061-gxv8y146	398	14	terms	term	NNS
cord-024061-gxv8y146	398	15	of	of	IN
cord-024061-gxv8y146	398	16	reporting	reporting	NN
cord-024061-gxv8y146	398	17	and	and	CC
cord-024061-gxv8y146	398	18	data	datum	NNS
cord-024061-gxv8y146	398	19	sharing	sharing	NN
cord-024061-gxv8y146	398	20	,	,	,
cord-024061-gxv8y146	398	21	when	when	WRB
cord-024061-gxv8y146	398	22	compared	compare	VBN
cord-024061-gxv8y146	398	23	to	to	IN
cord-024061-gxv8y146	398	24	their	-PRON-	PRP$
cord-024061-gxv8y146	398	25	human	human	JJ
cord-024061-gxv8y146	398	26	health	health	NN
cord-024061-gxv8y146	398	27	sectors	sector	NNS
cord-024061-gxv8y146	398	28	.	.	.
cord-024061-gxv8y146	399	1	Consequently	consequently	RB
cord-024061-gxv8y146	399	2	,	,	,
cord-024061-gxv8y146	399	3	the	the	DT
cord-024061-gxv8y146	399	4	question	question	NN
cord-024061-gxv8y146	399	5	related	relate	VBN
cord-024061-gxv8y146	399	6	to	to	IN
cord-024061-gxv8y146	399	7	the	the	DT
cord-024061-gxv8y146	399	8	future	future	NN
cord-024061-gxv8y146	399	9	of	of	IN
cord-024061-gxv8y146	399	10	implementing	implement	VBG
cord-024061-gxv8y146	399	11	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	399	12	methods	method	NNS
cord-024061-gxv8y146	399	13	in	in	IN
cord-024061-gxv8y146	399	14	global	global	JJ
cord-024061-gxv8y146	399	15	animal	animal	NN
cord-024061-gxv8y146	399	16	surveillance	surveillance	NN
cord-024061-gxv8y146	399	17	remains	remain	VBZ
cord-024061-gxv8y146	399	18	unanswered	unanswered	JJ
cord-024061-gxv8y146	399	19	.	.	.
cord-024061-gxv8y146	400	1	Our	-PRON-	PRP$
cord-024061-gxv8y146	400	2	selected	select	VBN
cord-024061-gxv8y146	400	3	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	400	4	analytical	analytical	JJ
cord-024061-gxv8y146	400	5	pipeline	pipeline	NN
cord-024061-gxv8y146	400	6	offers	offer	VBZ
cord-024061-gxv8y146	400	7	an	an	DT
cord-024061-gxv8y146	400	8	integrated	integrated	JJ
cord-024061-gxv8y146	400	9	approach	approach	NN
cord-024061-gxv8y146	400	10	to	to	IN
cord-024061-gxv8y146	400	11	not	not	RB
cord-024061-gxv8y146	400	12	only	only	RB
cord-024061-gxv8y146	400	13	answering	answer	VBG
cord-024061-gxv8y146	400	14	more	more	RBR
cord-024061-gxv8y146	400	15	profound	profound	JJ
cord-024061-gxv8y146	400	16	epidemiological	epidemiological	JJ
cord-024061-gxv8y146	400	17	questions	question	NNS
cord-024061-gxv8y146	400	18	about	about	IN
cord-024061-gxv8y146	400	19	emerging	emerge	VBG
cord-024061-gxv8y146	400	20	and	and	CC
cord-024061-gxv8y146	400	21	endemic	endemic	JJ
cord-024061-gxv8y146	400	22	animal	animal	NN
cord-024061-gxv8y146	400	23	diseases	disease	NNS
cord-024061-gxv8y146	400	24	but	but	CC
cord-024061-gxv8y146	400	25	also	also	RB
cord-024061-gxv8y146	400	26	attempts	attempt	VBZ
cord-024061-gxv8y146	400	27	to	to	TO
cord-024061-gxv8y146	400	28	reduce	reduce	VB
cord-024061-gxv8y146	400	29	the	the	DT
cord-024061-gxv8y146	400	30	impact	impact	NN
cord-024061-gxv8y146	400	31	of	of	IN
cord-024061-gxv8y146	400	32	its	-PRON-	PRP$
cord-024061-gxv8y146	400	33	inherent	inherent	JJ
cord-024061-gxv8y146	400	34	limitations	limitation	NNS
cord-024061-gxv8y146	400	35	to	to	TO
cord-024061-gxv8y146	400	36	offer	offer	VB
cord-024061-gxv8y146	400	37	less	less	RBR
cord-024061-gxv8y146	400	38	biased	biased	JJ
cord-024061-gxv8y146	400	39	and	and	CC
cord-024061-gxv8y146	400	40	biologically	biologically	RB
cord-024061-gxv8y146	400	41	plausible	plausible	JJ
cord-024061-gxv8y146	400	42	inferences	inference	NNS
cord-024061-gxv8y146	400	43	about	about	IN
cord-024061-gxv8y146	400	44	the	the	DT
cord-024061-gxv8y146	400	45	pathogen	pathogen	NN
cord-024061-gxv8y146	400	46	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	400	47	characteristics	characteristic	NNS
cord-024061-gxv8y146	400	48	to	to	TO
cord-024061-gxv8y146	400	49	properly	properly	RB
cord-024061-gxv8y146	400	50	guide	guide	VB
cord-024061-gxv8y146	400	51	intervention	intervention	NN
cord-024061-gxv8y146	400	52	activities	activity	NNS
cord-024061-gxv8y146	400	53	.	.	.
cord-024061-gxv8y146	401	1	This	this	DT
cord-024061-gxv8y146	401	2	study	study	NN
cord-024061-gxv8y146	401	3	has	have	VBZ
cord-024061-gxv8y146	401	4	highlighted	highlight	VBN
cord-024061-gxv8y146	401	5	the	the	DT
cord-024061-gxv8y146	401	6	value	value	NN
cord-024061-gxv8y146	401	7	of	of	IN
cord-024061-gxv8y146	401	8	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	401	9	methods	method	NNS
cord-024061-gxv8y146	401	10	in	in	IN
cord-024061-gxv8y146	401	11	improving	improve	VBG
cord-024061-gxv8y146	401	12	current	current	JJ
cord-024061-gxv8y146	401	13	and	and	CC
cord-024061-gxv8y146	401	14	future	future	JJ
cord-024061-gxv8y146	401	15	molecular	molecular	JJ
cord-024061-gxv8y146	401	16	surveillance	surveillance	NN
cord-024061-gxv8y146	401	17	efforts	effort	NNS
cord-024061-gxv8y146	401	18	against	against	IN
cord-024061-gxv8y146	401	19	animal	animal	NN
cord-024061-gxv8y146	401	20	diseases	disease	NNS
cord-024061-gxv8y146	401	21	using	use	VBG
cord-024061-gxv8y146	401	22	human	human	NN
cord-024061-gxv8y146	401	23	-	-	HYPH
cord-024061-gxv8y146	401	24	like	like	JJ
cord-024061-gxv8y146	401	25	H3	H3	NNP
cord-024061-gxv8y146	401	26	SI	SI	NNP
cord-024061-gxv8y146	401	27	virus	virus	NN
cord-024061-gxv8y146	401	28	as	as	IN
cord-024061-gxv8y146	401	29	a	a	DT
cord-024061-gxv8y146	401	30	working	work	VBG
cord-024061-gxv8y146	401	31	example	example	NN
cord-024061-gxv8y146	401	32	.	.	.
cord-024061-gxv8y146	402	1	We	-PRON-	PRP
cord-024061-gxv8y146	402	2	reviewed	review	VBD
cord-024061-gxv8y146	402	3	and	and	CC
cord-024061-gxv8y146	402	4	outlined	outline	VBD
cord-024061-gxv8y146	402	5	basic	basic	JJ
cord-024061-gxv8y146	402	6	concepts	concept	NNS
cord-024061-gxv8y146	402	7	and	and	CC
cord-024061-gxv8y146	402	8	aspects	aspect	NNS
cord-024061-gxv8y146	402	9	of	of	IN
cord-024061-gxv8y146	402	10	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	402	11	methods	method	NNS
cord-024061-gxv8y146	402	12	and	and	CC
cord-024061-gxv8y146	402	13	attempted	attempt	VBD
cord-024061-gxv8y146	402	14	to	to	TO
cord-024061-gxv8y146	402	15	summarize	summarize	VB
cord-024061-gxv8y146	402	16	essential	essential	JJ
cord-024061-gxv8y146	402	17	components	component	NNS
cord-024061-gxv8y146	402	18	of	of	IN
cord-024061-gxv8y146	402	19	the	the	DT
cord-024061-gxv8y146	402	20	methodology	methodology	NN
cord-024061-gxv8y146	402	21	in	in	IN
cord-024061-gxv8y146	402	22	one	one	CD
cord-024061-gxv8y146	402	23	analytical	analytical	JJ
cord-024061-gxv8y146	402	24	pipeline	pipeline	NN
cord-024061-gxv8y146	402	25	to	to	TO
cord-024061-gxv8y146	402	26	facilitate	facilitate	VB
cord-024061-gxv8y146	402	27	the	the	DT
cord-024061-gxv8y146	402	28	proper	proper	JJ
cord-024061-gxv8y146	402	29	use	use	NN
cord-024061-gxv8y146	402	30	of	of	IN
cord-024061-gxv8y146	402	31	the	the	DT
cord-024061-gxv8y146	402	32	methods	method	NNS
cord-024061-gxv8y146	402	33	by	by	IN
cord-024061-gxv8y146	402	34	animal	animal	NN
cord-024061-gxv8y146	402	35	health	health	NN
cord-024061-gxv8y146	402	36	researchers	researcher	NNS
cord-024061-gxv8y146	402	37	.	.	.
cord-024061-gxv8y146	403	1	We	-PRON-	PRP
cord-024061-gxv8y146	403	2	also	also	RB
cord-024061-gxv8y146	403	3	pinpointed	pinpoint	VBD
cord-024061-gxv8y146	403	4	requirements	requirement	NNS
cord-024061-gxv8y146	403	5	and	and	CC
cord-024061-gxv8y146	403	6	challenges	challenge	NNS
cord-024061-gxv8y146	403	7	for	for	IN
cord-024061-gxv8y146	403	8	integrating	integrate	VBG
cord-024061-gxv8y146	403	9	phylodynamic	phylodynamic	JJ
cord-024061-gxv8y146	403	10	methods	method	NNS
cord-024061-gxv8y146	403	11	in	in	IN
cord-024061-gxv8y146	403	12	routine	routine	JJ
cord-024061-gxv8y146	403	13	animal	animal	NN
cord-024061-gxv8y146	403	14	disease	disease	NN
cord-024061-gxv8y146	403	15	surveillance	surveillance	NN
cord-024061-gxv8y146	403	16	activities	activity	NNS
cord-024061-gxv8y146	403	17	.	.	.
cord-024061-gxv8y146	404	1	The	the	DT
cord-024061-gxv8y146	404	2	datasets	dataset	NNS
cord-024061-gxv8y146	404	3	analyzed	analyze	VBN
cord-024061-gxv8y146	404	4	for	for	IN
cord-024061-gxv8y146	404	5	this	this	DT
cord-024061-gxv8y146	404	6	study	study	NN
cord-024061-gxv8y146	404	7	(	(	-LRB-
cord-024061-gxv8y146	404	8	Alignments	alignment	NNS
cord-024061-gxv8y146	404	9	,	,	,
cord-024061-gxv8y146	404	10	BEAST	BEAST	NNP
cord-024061-gxv8y146	404	11	xmls	xmls	NNP
cord-024061-gxv8y146	404	12	,	,	,
cord-024061-gxv8y146	404	13	and	and	CC
cord-024061-gxv8y146	404	14	MCC	MCC	NNP
cord-024061-gxv8y146	404	15	tree	tree	NN
cord-024061-gxv8y146	404	16	files	file	NNS
cord-024061-gxv8y146	404	17	)	)	-RRB-
cord-024061-gxv8y146	404	18	can	can	MD
cord-024061-gxv8y146	404	19	be	be	VB
cord-024061-gxv8y146	404	20	found	find	VBN
cord-024061-gxv8y146	404	21	in	in	IN
cord-024061-gxv8y146	404	22	the	the	DT
cord-024061-gxv8y146	404	23	Figshare	Figshare	NNP
cord-024061-gxv8y146	404	24	Dataset	Dataset	NNP
cord-024061-gxv8y146	404	25	.	.	.
cord-024061-gxv8y146	405	1	https://	https://	NNP
cord-024061-gxv8y146	405	2	doi.org/10.6084/m9.figshare.11842989.v1	doi.org/10.6084/m9.figshare.11842989.v1	NNP
cord-024061-gxv8y146	405	3	.	.	.
cord-024061-gxv8y146	406	1	Carlsson	Carlsson	NNP
cord-024061-gxv8y146	406	2	:	:	:
cord-024061-gxv8y146	406	3	global	global	JJ
cord-024061-gxv8y146	406	4	animal	animal	NN
cord-024061-gxv8y146	406	5	disease	disease	NN
cord-024061-gxv8y146	406	6	surveillance	surveillance	NN
cord-024061-gxv8y146	406	7	Novel	Novel	NNP
cord-024061-gxv8y146	406	8	analytic	analytic	JJ
cord-024061-gxv8y146	406	9	tools	tool	NNS
cord-024061-gxv8y146	406	10	for	for	IN
cord-024061-gxv8y146	406	11	the	the	DT
cord-024061-gxv8y146	406	12	study	study	NN
cord-024061-gxv8y146	406	13	of	of	IN
cord-024061-gxv8y146	406	14	porcine	porcine	JJ
cord-024061-gxv8y146	406	15	reproductive	reproductive	JJ
cord-024061-gxv8y146	406	16	and	and	CC
cord-024061-gxv8y146	406	17	respiratory	respiratory	JJ
cord-024061-gxv8y146	406	18	syndrome	syndrome	NN
cord-024061-gxv8y146	406	19	virus	virus	NN
cord-024061-gxv8y146	406	20	(	(	-LRB-
cord-024061-gxv8y146	406	21	PRRSv	PRRSv	NNS
cord-024061-gxv8y146	406	22	)	)	-RRB-
cord-024061-gxv8y146	406	23	in	in	IN
cord-024061-gxv8y146	406	24	endemic	endemic	JJ
cord-024061-gxv8y146	406	25	settings	setting	NNS
cord-024061-gxv8y146	406	26	:	:	:
cord-024061-gxv8y146	406	27	lessons	lesson	NNS
cord-024061-gxv8y146	406	28	learned	learn	VBN
cord-024061-gxv8y146	406	29	in	in	IN
cord-024061-gxv8y146	406	30	the	the	DT
cord-024061-gxv8y146	406	31	U.S.	U.S.	NNP
cord-024061-gxv8y146	407	1	Porcine	Porcine	NNP
cord-024061-gxv8y146	407	2	Health	Health	NNP
cord-024061-gxv8y146	407	3	Manag	Manag	NNP
cord-024061-gxv8y146	407	4	A	A	NNP
cord-024061-gxv8y146	407	5	Review	Review	NNP
cord-024061-gxv8y146	407	6	of	of	IN
cord-024061-gxv8y146	407	7	quantitative	quantitative	JJ
cord-024061-gxv8y146	407	8	tools	tool	NNS
cord-024061-gxv8y146	407	9	used	use	VBN
cord-024061-gxv8y146	407	10	to	to	TO
cord-024061-gxv8y146	407	11	assess	assess	VB
cord-024061-gxv8y146	407	12	the	the	DT
cord-024061-gxv8y146	407	13	epidemiology	epidemiology	NN
cord-024061-gxv8y146	407	14	of	of	IN
cord-024061-gxv8y146	407	15	porcine	porcine	JJ
cord-024061-gxv8y146	407	16	reproductive	reproductive	JJ
cord-024061-gxv8y146	407	17	and	and	CC
cord-024061-gxv8y146	407	18	respiratory	respiratory	JJ
cord-024061-gxv8y146	407	19	syndrome	syndrome	NN
cord-024061-gxv8y146	407	20	in	in	IN
cord-024061-gxv8y146	407	21	U.S.	U.S.	NNP
cord-024061-gxv8y146	407	22	swine	swine	NN
cord-024061-gxv8y146	407	23	farms	farm	NNS
cord-024061-gxv8y146	407	24	using	use	VBG
cord-024061-gxv8y146	407	25	dr	dr	NNP
cord-024061-gxv8y146	407	26	.	.	NNP
cord-024061-gxv8y146	407	27	morrison	morrison	NNP
cord-024061-gxv8y146	407	28	's	's	POS
cord-024061-gxv8y146	407	29	swine	swine	NNP
cord-024061-gxv8y146	407	30	health	health	NNP
cord-024061-gxv8y146	407	31	monitoring	monitor	VBG
cord-024061-gxv8y146	407	32	program	program	NN
cord-024061-gxv8y146	407	33	data	datum	NNS
cord-024061-gxv8y146	407	34	.	.	.
cord-024061-gxv8y146	408	1	Front	front	JJ
cord-024061-gxv8y146	408	2	Vet	Vet	NNP
cord-024061-gxv8y146	408	3	Sci	Sci	NNP
cord-024061-gxv8y146	409	1	Towards	towards	IN
cord-024061-gxv8y146	409	2	a	a	DT
cord-024061-gxv8y146	409	3	genomics	genomics	NN
cord-024061-gxv8y146	409	4	-	-	HYPH
cord-024061-gxv8y146	409	5	informed	inform	VBN
cord-024061-gxv8y146	409	6	,	,	,
cord-024061-gxv8y146	409	7	real	real	JJ
cord-024061-gxv8y146	409	8	-	-	HYPH
cord-024061-gxv8y146	409	9	time	time	NN
cord-024061-gxv8y146	409	10	,	,	,
cord-024061-gxv8y146	409	11	global	global	JJ
cord-024061-gxv8y146	409	12	pathogen	pathogen	NN
cord-024061-gxv8y146	409	13	surveillance	surveillance	NN
cord-024061-gxv8y146	409	14	system	system	NN
cord-024061-gxv8y146	409	15	Highly	highly	RB
cord-024061-gxv8y146	409	16	pathogenic	pathogenic	JJ
cord-024061-gxv8y146	409	17	avian	avian	JJ
cord-024061-gxv8y146	409	18	influenza	influenza	NN
cord-024061-gxv8y146	409	19	virus	virus	NN
cord-024061-gxv8y146	409	20	subtype	subtype	NN
cord-024061-gxv8y146	409	21	H5N1	H5N1	NNP
cord-024061-gxv8y146	409	22	in	in	IN
cord-024061-gxv8y146	409	23	Africa	Africa	NNP
cord-024061-gxv8y146	409	24	:	:	:
cord-024061-gxv8y146	409	25	a	a	DT
cord-024061-gxv8y146	409	26	comprehensive	comprehensive	JJ
cord-024061-gxv8y146	409	27	phylogenetic	phylogenetic	JJ
cord-024061-gxv8y146	409	28	analysis	analysis	NN
cord-024061-gxv8y146	409	29	and	and	CC
cord-024061-gxv8y146	409	30	molecular	molecular	JJ
cord-024061-gxv8y146	409	31	characterization	characterization	NN
cord-024061-gxv8y146	409	32	of	of	IN
cord-024061-gxv8y146	409	33	isolates	isolate	NNS
cord-024061-gxv8y146	409	34	Regional	regional	JJ
cord-024061-gxv8y146	409	35	patterns	pattern	NNS
cord-024061-gxv8y146	409	36	of	of	IN
cord-024061-gxv8y146	409	37	genetic	genetic	JJ
cord-024061-gxv8y146	409	38	diversity	diversity	NN
cord-024061-gxv8y146	409	39	in	in	IN
cord-024061-gxv8y146	409	40	swine	swine	NN
cord-024061-gxv8y146	409	41	influenza	influenza	NN
cord-024061-gxv8y146	410	1	a	a	DT
cord-024061-gxv8y146	410	2	viruses	virus	NNS
cord-024061-gxv8y146	410	3	in	in	IN
cord-024061-gxv8y146	410	4	the	the	DT
cord-024061-gxv8y146	410	5	United	United	NNP
cord-024061-gxv8y146	410	6	States	States	NNP
cord-024061-gxv8y146	410	7	from	from	IN
cord-024061-gxv8y146	410	8	Influenza	Influenza	NNP
cord-024061-gxv8y146	410	9	aH5N1	aH5N1	NNP
cord-024061-gxv8y146	410	10	immigration	immigration	NN
cord-024061-gxv8y146	410	11	is	be	VBZ
cord-024061-gxv8y146	410	12	filtered	filter	VBN
cord-024061-gxv8y146	410	13	out	out	RP
cord-024061-gxv8y146	410	14	at	at	IN
cord-024061-gxv8y146	410	15	some	some	DT
cord-024061-gxv8y146	410	16	international	international	JJ
cord-024061-gxv8y146	410	17	borders	border	NNS
cord-024061-gxv8y146	410	18	Molecular	Molecular	NNP
cord-024061-gxv8y146	410	19	epidemiology	epidemiology	NN
cord-024061-gxv8y146	410	20	of	of	IN
cord-024061-gxv8y146	410	21	foot	foot	NN
cord-024061-gxv8y146	410	22	-	-	HYPH
cord-024061-gxv8y146	410	23	and	and	CC
cord-024061-gxv8y146	410	24	-	-	HYPH
cord-024061-gxv8y146	410	25	mouth	mouth	NN
cord-024061-gxv8y146	410	26	disease	disease	NN
cord-024061-gxv8y146	410	27	virus	virus	NN
cord-024061-gxv8y146	410	28	Comparative	Comparative	NNP
cord-024061-gxv8y146	410	29	study	study	NN
cord-024061-gxv8y146	410	30	of	of	IN
cord-024061-gxv8y146	410	31	codon	codon	NN
cord-024061-gxv8y146	410	32	substitution	substitution	NN
cord-024061-gxv8y146	410	33	patterns	pattern	NNS
cord-024061-gxv8y146	410	34	in	in	IN
cord-024061-gxv8y146	410	35	foot	foot	NN
cord-024061-gxv8y146	410	36	-	-	HYPH
cord-024061-gxv8y146	410	37	and	and	CC
cord-024061-gxv8y146	410	38	-	-	HYPH
cord-024061-gxv8y146	410	39	mouth	mouth	NN
cord-024061-gxv8y146	410	40	disease	disease	NN
cord-024061-gxv8y146	410	41	virus	virus	NN
cord-024061-gxv8y146	410	42	(	(	-LRB-
cord-024061-gxv8y146	410	43	serotype	serotype	NN
cord-024061-gxv8y146	410	44	O	o	NN
cord-024061-gxv8y146	410	45	)	)	-RRB-
cord-024061-gxv8y146	410	46	Foot	foot	NN
cord-024061-gxv8y146	410	47	-	-	HYPH
cord-024061-gxv8y146	410	48	and	and	CC
cord-024061-gxv8y146	410	49	-	-	HYPH
cord-024061-gxv8y146	410	50	mouth	mouth	NN
cord-024061-gxv8y146	410	51	disease	disease	NN
cord-024061-gxv8y146	410	52	:	:	:
cord-024061-gxv8y146	410	53	past	past	JJ
cord-024061-gxv8y146	410	54	,	,	,
cord-024061-gxv8y146	410	55	present	present	JJ
cord-024061-gxv8y146	410	56	and	and	CC
cord-024061-gxv8y146	410	57	future	future	JJ
cord-024061-gxv8y146	410	58	Spatial	spatial	JJ
cord-024061-gxv8y146	410	59	and	and	CC
cord-024061-gxv8y146	410	60	temporal	temporal	JJ
cord-024061-gxv8y146	410	61	patterns	pattern	NNS
cord-024061-gxv8y146	410	62	of	of	IN
cord-024061-gxv8y146	410	63	porcine	porcine	JJ
cord-024061-gxv8y146	410	64	reproductive	reproductive	JJ
cord-024061-gxv8y146	410	65	and	and	CC
cord-024061-gxv8y146	410	66	respiratory	respiratory	JJ
cord-024061-gxv8y146	410	67	syndrome	syndrome	NN
cord-024061-gxv8y146	410	68	virus	virus	NN
cord-024061-gxv8y146	410	69	(	(	-LRB-
cord-024061-gxv8y146	410	70	PRRSV	PRRSV	NNP
cord-024061-gxv8y146	410	71	)	)	-RRB-
cord-024061-gxv8y146	410	72	genotypes	genotype	NNS
cord-024061-gxv8y146	410	73	in	in	IN
cord-024061-gxv8y146	410	74	Ontario	Ontario	NNP
cord-024061-gxv8y146	410	75	,	,	,
cord-024061-gxv8y146	410	76	Canada	Canada	NNP
cord-024061-gxv8y146	410	77	Analysis	Analysis	NNP
cord-024061-gxv8y146	410	78	of	of	IN
cord-024061-gxv8y146	410	79	ORF5	ORF5	NNP
cord-024061-gxv8y146	410	80	and	and	CC
cord-024061-gxv8y146	410	81	full	full	JJ
cord-024061-gxv8y146	410	82	-	-	HYPH
cord-024061-gxv8y146	410	83	length	length	NN
cord-024061-gxv8y146	410	84	genome	genome	NN
cord-024061-gxv8y146	410	85	sequences	sequence	NNS
cord-024061-gxv8y146	410	86	of	of	IN
cord-024061-gxv8y146	410	87	porcine	porcine	JJ
cord-024061-gxv8y146	410	88	reproductive	reproductive	JJ
cord-024061-gxv8y146	410	89	and	and	CC
cord-024061-gxv8y146	410	90	respiratory	respiratory	JJ
cord-024061-gxv8y146	410	91	syndrome	syndrome	NN
cord-024061-gxv8y146	410	92	virus	virus	NN
cord-024061-gxv8y146	410	93	isolates	isolate	VBZ
cord-024061-gxv8y146	410	94	of	of	IN
cord-024061-gxv8y146	410	95	genotypes	genotype	NNS
cord-024061-gxv8y146	410	96	1	1	CD
cord-024061-gxv8y146	410	97	and	and	CC
cord-024061-gxv8y146	410	98	2	2	CD
cord-024061-gxv8y146	410	99	retrieved	retrieve	VBN
cord-024061-gxv8y146	410	100	worldwide	worldwide	RB
cord-024061-gxv8y146	410	101	provides	provide	VBZ
cord-024061-gxv8y146	410	102	evidence	evidence	NN
cord-024061-gxv8y146	410	103	that	that	IN
cord-024061-gxv8y146	410	104	recombination	recombination	NN
cord-024061-gxv8y146	410	105	is	be	VBZ
cord-024061-gxv8y146	410	106	a	a	DT
cord-024061-gxv8y146	410	107	common	common	JJ
cord-024061-gxv8y146	410	108	phenomenon	phenomenon	NN
cord-024061-gxv8y146	410	109	and	and	CC
cord-024061-gxv8y146	410	110	may	may	MD
cord-024061-gxv8y146	410	111	produce	produce	VB
cord-024061-gxv8y146	410	112	mosaic	mosaic	NN
cord-024061-gxv8y146	410	113	isolates	isolate	NNS
cord-024061-gxv8y146	410	114	Molecular	molecular	JJ
cord-024061-gxv8y146	410	115	evolution	evolution	NN
cord-024061-gxv8y146	410	116	of	of	IN
cord-024061-gxv8y146	410	117	PRRSV	PRRSV	NNP
cord-024061-gxv8y146	410	118	in	in	IN
cord-024061-gxv8y146	410	119	Europe	Europe	NNP
cord-024061-gxv8y146	410	120	:	:	:
cord-024061-gxv8y146	410	121	current	current	JJ
cord-024061-gxv8y146	410	122	state	state	NN
cord-024061-gxv8y146	410	123	of	of	IN
cord-024061-gxv8y146	410	124	play	play	NN
cord-024061-gxv8y146	410	125	Bayesian	Bayesian	NNP
cord-024061-gxv8y146	410	126	selection	selection	NN
cord-024061-gxv8y146	410	127	of	of	IN
cord-024061-gxv8y146	410	128	continuoustime	continuoustime	NNP
cord-024061-gxv8y146	410	129	Markov	Markov	NNP
cord-024061-gxv8y146	410	130	chain	chain	NN
cord-024061-gxv8y146	410	131	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	410	132	models	model	NNS
cord-024061-gxv8y146	410	133	Unifying	unify	VBG
cord-024061-gxv8y146	410	134	the	the	DT
cord-024061-gxv8y146	410	135	spatial	spatial	JJ
cord-024061-gxv8y146	410	136	epidemiology	epidemiology	NN
cord-024061-gxv8y146	410	137	and	and	CC
cord-024061-gxv8y146	410	138	molecular	molecular	JJ
cord-024061-gxv8y146	410	139	evolution	evolution	NN
cord-024061-gxv8y146	410	140	of	of	IN
cord-024061-gxv8y146	410	141	emerging	emerge	VBG
cord-024061-gxv8y146	410	142	epidemics	epidemic	NNS
cord-024061-gxv8y146	410	143	Evolutionary	evolutionary	JJ
cord-024061-gxv8y146	410	144	analysis	analysis	NN
cord-024061-gxv8y146	410	145	of	of	IN
cord-024061-gxv8y146	410	146	the	the	DT
cord-024061-gxv8y146	410	147	dynamics	dynamic	NNS
cord-024061-gxv8y146	410	148	of	of	IN
cord-024061-gxv8y146	410	149	viral	viral	JJ
cord-024061-gxv8y146	410	150	infectious	infectious	JJ
cord-024061-gxv8y146	410	151	disease	disease	NN
cord-024061-gxv8y146	410	152	Tracking	tracking	NN
cord-024061-gxv8y146	410	153	virus	virus	NN
cord-024061-gxv8y146	410	154	outbreaks	outbreak	NNS
cord-024061-gxv8y146	410	155	in	in	IN
cord-024061-gxv8y146	410	156	the	the	DT
cord-024061-gxv8y146	410	157	twenty	twenty	CD
cord-024061-gxv8y146	410	158	-	-	HYPH
cord-024061-gxv8y146	410	159	first	first	JJ
cord-024061-gxv8y146	410	160	century	century	NN
cord-024061-gxv8y146	410	161	Evidence	evidence	NN
cord-024061-gxv8y146	410	162	for	for	IN
cord-024061-gxv8y146	410	163	positive	positive	JJ
cord-024061-gxv8y146	410	164	selection	selection	NN
cord-024061-gxv8y146	410	165	in	in	IN
cord-024061-gxv8y146	410	166	foot	foot	NN
cord-024061-gxv8y146	410	167	-	-	HYPH
cord-024061-gxv8y146	410	168	and	and	CC
cord-024061-gxv8y146	410	169	-	-	HYPH
cord-024061-gxv8y146	410	170	mouth	mouth	NN
cord-024061-gxv8y146	410	171	disease	disease	NN
cord-024061-gxv8y146	410	172	virus	virus	NN
cord-024061-gxv8y146	410	173	capsid	capsid	NN
cord-024061-gxv8y146	410	174	genes	gene	NNS
cord-024061-gxv8y146	410	175	from	from	IN
cord-024061-gxv8y146	410	176	field	field	NN
cord-024061-gxv8y146	411	1	isolates	isolate	NNS
cord-024061-gxv8y146	412	1	Phylogeography	phylogeography	NN
cord-024061-gxv8y146	412	2	takes	take	VBZ
cord-024061-gxv8y146	412	3	a	a	DT
cord-024061-gxv8y146	412	4	relaxed	relaxed	JJ
cord-024061-gxv8y146	412	5	random	random	JJ
cord-024061-gxv8y146	412	6	walk	walk	NN
cord-024061-gxv8y146	412	7	in	in	IN
cord-024061-gxv8y146	412	8	continuous	continuous	JJ
cord-024061-gxv8y146	412	9	space	space	NN
cord-024061-gxv8y146	412	10	and	and	CC
cord-024061-gxv8y146	412	11	time	time	NN
cord-024061-gxv8y146	412	12	Combining	combine	VBG
cord-024061-gxv8y146	412	13	phylogeography	phylogeography	NN
cord-024061-gxv8y146	412	14	and	and	CC
cord-024061-gxv8y146	412	15	spatial	spatial	JJ
cord-024061-gxv8y146	412	16	epidemiology	epidemiology	NN
cord-024061-gxv8y146	412	17	to	to	TO
cord-024061-gxv8y146	412	18	uncover	uncover	VB
cord-024061-gxv8y146	412	19	predictors	predictor	NNS
cord-024061-gxv8y146	412	20	of	of	IN
cord-024061-gxv8y146	412	21	H5N1	H5N1	NNP
cord-024061-gxv8y146	412	22	influenza	influenza	NN
cord-024061-gxv8y146	412	23	a	a	DT
cord-024061-gxv8y146	412	24	virus	virus	NN
cord-024061-gxv8y146	412	25	diffusion	diffusion	NN
cord-024061-gxv8y146	412	26	Novel	Novel	NNP
cord-024061-gxv8y146	412	27	approaches	approach	NNS
cord-024061-gxv8y146	412	28	for	for	IN
cord-024061-gxv8y146	412	29	spatial	spatial	JJ
cord-024061-gxv8y146	412	30	and	and	CC
cord-024061-gxv8y146	412	31	molecular	molecular	JJ
cord-024061-gxv8y146	412	32	surveillance	surveillance	NN
cord-024061-gxv8y146	412	33	of	of	IN
cord-024061-gxv8y146	412	34	Porcine	porcine	JJ
cord-024061-gxv8y146	412	35	Reproductive	Reproductive	NNP
cord-024061-gxv8y146	412	36	and	and	CC
cord-024061-gxv8y146	412	37	Respiratory	Respiratory	NNP
cord-024061-gxv8y146	412	38	Syndrome	Syndrome	NNP
cord-024061-gxv8y146	412	39	Virus	virus	NN
cord-024061-gxv8y146	412	40	(	(	-LRB-
cord-024061-gxv8y146	412	41	PRRSv	PRRSv	NNS
cord-024061-gxv8y146	412	42	)	)	-RRB-
cord-024061-gxv8y146	412	43	in	in	IN
cord-024061-gxv8y146	412	44	the	the	DT
cord-024061-gxv8y146	412	45	United	United	NNP
cord-024061-gxv8y146	412	46	States	States	NNP
cord-024061-gxv8y146	412	47	.	.	.
cord-024061-gxv8y146	413	1	Sci	Sci	NNP
cord-024061-gxv8y146	413	2	Rep	Rep	NNP
cord-024061-gxv8y146	413	3	Unifying	Unifying	NNP
cord-024061-gxv8y146	413	4	viral	viral	JJ
cord-024061-gxv8y146	413	5	genetics	genetic	NNS
cord-024061-gxv8y146	413	6	and	and	CC
cord-024061-gxv8y146	413	7	human	human	JJ
cord-024061-gxv8y146	413	8	transportation	transportation	NN
cord-024061-gxv8y146	413	9	data	datum	NNS
cord-024061-gxv8y146	413	10	to	to	TO
cord-024061-gxv8y146	413	11	predict	predict	VB
cord-024061-gxv8y146	413	12	the	the	DT
cord-024061-gxv8y146	413	13	global	global	JJ
cord-024061-gxv8y146	413	14	transmission	transmission	NN
cord-024061-gxv8y146	413	15	dynamics	dynamic	NNS
cord-024061-gxv8y146	413	16	of	of	IN
cord-024061-gxv8y146	413	17	human	human	JJ
cord-024061-gxv8y146	413	18	influenza	influenza	NN
cord-024061-gxv8y146	413	19	H3N2	H3N2	NNP
cord-024061-gxv8y146	413	20	Widespread	widespread	JJ
cord-024061-gxv8y146	413	21	reassortment	reassortment	NN
cord-024061-gxv8y146	413	22	shapes	shape	VBZ
cord-024061-gxv8y146	413	23	the	the	DT
cord-024061-gxv8y146	413	24	evolution	evolution	NN
cord-024061-gxv8y146	413	25	and	and	CC
cord-024061-gxv8y146	413	26	epidemiology	epidemiology	NN
cord-024061-gxv8y146	413	27	of	of	IN
cord-024061-gxv8y146	413	28	bluetongue	bluetongue	NN
cord-024061-gxv8y146	413	29	virus	virus	NN
cord-024061-gxv8y146	413	30	following	follow	VBG
cord-024061-gxv8y146	413	31	European	european	JJ
cord-024061-gxv8y146	413	32	invasion	invasion	NN
cord-024061-gxv8y146	413	33	Bayesian	bayesian	JJ
cord-024061-gxv8y146	413	34	phylogenetic	phylogenetic	NN
cord-024061-gxv8y146	413	35	and	and	CC
cord-024061-gxv8y146	413	36	phylodynamic	phylodynamic	NNP
cord-024061-gxv8y146	413	37	data	datum	NNS
cord-024061-gxv8y146	413	38	integration	integration	NN
cord-024061-gxv8y146	413	39	using	use	VBG
cord-024061-gxv8y146	413	40	BEAST	BEAST	NNP
cord-024061-gxv8y146	413	41	1.10	1.10	CD
cord-024061-gxv8y146	413	42	Improving	improve	VBG
cord-024061-gxv8y146	413	43	the	the	DT
cord-024061-gxv8y146	413	44	accuracy	accuracy	NN
cord-024061-gxv8y146	413	45	of	of	IN
cord-024061-gxv8y146	413	46	demographic	demographic	JJ
cord-024061-gxv8y146	413	47	and	and	CC
cord-024061-gxv8y146	413	48	molecular	molecular	JJ
cord-024061-gxv8y146	413	49	clock	clock	NN
cord-024061-gxv8y146	413	50	model	model	NN
cord-024061-gxv8y146	413	51	comparison	comparison	NN
cord-024061-gxv8y146	413	52	while	while	IN
cord-024061-gxv8y146	413	53	accommodating	accommodate	VBG
cord-024061-gxv8y146	413	54	phylogenetic	phylogenetic	JJ
cord-024061-gxv8y146	413	55	uncertainty	uncertainty	NN
cord-024061-gxv8y146	413	56	New	new	JJ
cord-024061-gxv8y146	413	57	routes	route	NNS
cord-024061-gxv8y146	413	58	to	to	IN
cord-024061-gxv8y146	413	59	phylogeography	phylogeography	NN
cord-024061-gxv8y146	413	60	:	:	:
cord-024061-gxv8y146	414	1	a	a	DT
cord-024061-gxv8y146	414	2	Bayesian	bayesian	JJ
cord-024061-gxv8y146	414	3	structured	structured	JJ
cord-024061-gxv8y146	414	4	coalescent	coalescent	NN
cord-024061-gxv8y146	414	5	approximation	approximation	NN
cord-024061-gxv8y146	414	6	Phylodynamic	Phylodynamic	NNP
cord-024061-gxv8y146	414	7	reconstruction	reconstruction	NN
cord-024061-gxv8y146	414	8	of	of	IN
cord-024061-gxv8y146	414	9	O	O	NNP
cord-024061-gxv8y146	414	10	CATHAY	CATHAY	NNP
cord-024061-gxv8y146	414	11	topotype	topotype	NNP
cord-024061-gxv8y146	414	12	foot	foot	NN
cord-024061-gxv8y146	414	13	-	-	HYPH
cord-024061-gxv8y146	414	14	andmouth	andmouth	NNP
cord-024061-gxv8y146	414	15	disease	disease	NN
cord-024061-gxv8y146	414	16	virus	virus	NN
cord-024061-gxv8y146	414	17	epidemics	epidemic	NNS
cord-024061-gxv8y146	414	18	in	in	IN
cord-024061-gxv8y146	414	19	the	the	DT
cord-024061-gxv8y146	414	20	Philippines	Philippines	NNP
cord-024061-gxv8y146	414	21	Phylodynamics	Phylodynamics	NNPS
cord-024061-gxv8y146	414	22	of	of	IN
cord-024061-gxv8y146	414	23	H1N1/2009	H1N1/2009	NNP
cord-024061-gxv8y146	414	24	influenza	influenza	NN
cord-024061-gxv8y146	414	25	reveals	reveal	VBZ
cord-024061-gxv8y146	414	26	the	the	DT
cord-024061-gxv8y146	414	27	transition	transition	NN
cord-024061-gxv8y146	414	28	from	from	IN
cord-024061-gxv8y146	414	29	host	host	NN
cord-024061-gxv8y146	414	30	adaptation	adaptation	NN
cord-024061-gxv8y146	414	31	to	to	IN
cord-024061-gxv8y146	414	32	immune	immune	NN
cord-024061-gxv8y146	414	33	-	-	HYPH
cord-024061-gxv8y146	414	34	driven	drive	VBN
cord-024061-gxv8y146	414	35	selection	selection	NN
cord-024061-gxv8y146	414	36	Transmission	transmission	NN
cord-024061-gxv8y146	414	37	dynamics	dynamic	NNS
cord-024061-gxv8y146	414	38	of	of	IN
cord-024061-gxv8y146	414	39	re	re	NN
cord-024061-gxv8y146	414	40	-	-	JJ
cord-024061-gxv8y146	414	41	emerging	emerge	VBG
cord-024061-gxv8y146	414	42	rabies	rabie	NNS
cord-024061-gxv8y146	414	43	in	in	IN
cord-024061-gxv8y146	414	44	domestic	domestic	JJ
cord-024061-gxv8y146	414	45	dogs	dog	NNS
cord-024061-gxv8y146	414	46	of	of	IN
cord-024061-gxv8y146	414	47	rural	rural	JJ
cord-024061-gxv8y146	414	48	China	China	NNP
cord-024061-gxv8y146	414	49	Genetic	genetic	JJ
cord-024061-gxv8y146	414	50	diversity	diversity	NN
cord-024061-gxv8y146	414	51	of	of	IN
cord-024061-gxv8y146	414	52	PRRS	PRRS	NNP
cord-024061-gxv8y146	414	53	virus	virus	NN
cord-024061-gxv8y146	414	54	collected	collect	VBN
cord-024061-gxv8y146	414	55	from	from	IN
cord-024061-gxv8y146	414	56	air	air	NN
cord-024061-gxv8y146	414	57	samples	sample	NNS
cord-024061-gxv8y146	414	58	in	in	IN
cord-024061-gxv8y146	414	59	four	four	CD
cord-024061-gxv8y146	414	60	different	different	JJ
cord-024061-gxv8y146	414	61	regions	region	NNS
cord-024061-gxv8y146	414	62	of	of	IN
cord-024061-gxv8y146	414	63	concentrated	concentrated	JJ
cord-024061-gxv8y146	414	64	swine	swine	NN
cord-024061-gxv8y146	414	65	production	production	NN
cord-024061-gxv8y146	414	66	during	during	IN
cord-024061-gxv8y146	414	67	a	a	DT
cord-024061-gxv8y146	414	68	high	high	JJ
cord-024061-gxv8y146	414	69	incidence	incidence	NN
cord-024061-gxv8y146	414	70	season	season	NN
cord-024061-gxv8y146	415	1	The	the	DT
cord-024061-gxv8y146	415	2	spread	spread	NN
cord-024061-gxv8y146	415	3	of	of	IN
cord-024061-gxv8y146	415	4	type	type	NN
cord-024061-gxv8y146	415	5	2	2	CD
cord-024061-gxv8y146	415	6	Porcine	porcine	JJ
cord-024061-gxv8y146	415	7	Reproductive	reproductive	JJ
cord-024061-gxv8y146	415	8	and	and	CC
cord-024061-gxv8y146	415	9	Respiratory	respiratory	JJ
cord-024061-gxv8y146	415	10	Syndrome	Syndrome	NNP
cord-024061-gxv8y146	415	11	Virus	Virus	NNP
cord-024061-gxv8y146	415	12	(	(	-LRB-
cord-024061-gxv8y146	415	13	PRRSV	PRRSV	NNP
cord-024061-gxv8y146	415	14	)	)	-RRB-
cord-024061-gxv8y146	415	15	in	in	IN
cord-024061-gxv8y146	415	16	North	North	NNP
cord-024061-gxv8y146	415	17	America	America	NNP
cord-024061-gxv8y146	415	18	:	:	:
cord-024061-gxv8y146	415	19	a	a	DT
cord-024061-gxv8y146	415	20	phylogeographic	phylogeographic	JJ
cord-024061-gxv8y146	415	21	approach	approach	NN
cord-024061-gxv8y146	415	22	Bayesian	bayesian	JJ
cord-024061-gxv8y146	415	23	phylogeography	phylogeography	NN
cord-024061-gxv8y146	415	24	of	of	IN
cord-024061-gxv8y146	415	25	influenza	influenza	NN
cord-024061-gxv8y146	415	26	A	A	NNP
cord-024061-gxv8y146	415	27	/	/	SYM
cord-024061-gxv8y146	415	28	H3N2	H3N2	NNP
cord-024061-gxv8y146	415	29	for	for	IN
cord-024061-gxv8y146	415	30	the	the	DT
cord-024061-gxv8y146	415	31	2014	2014	CD
cord-024061-gxv8y146	415	32	-	-	SYM
cord-024061-gxv8y146	415	33	15	15	CD
cord-024061-gxv8y146	415	34	season	season	NN
cord-024061-gxv8y146	415	35	in	in	IN
cord-024061-gxv8y146	415	36	the	the	DT
cord-024061-gxv8y146	415	37	United	United	NNP
cord-024061-gxv8y146	415	38	States	States	NNP
cord-024061-gxv8y146	415	39	using	use	VBG
cord-024061-gxv8y146	415	40	three	three	CD
cord-024061-gxv8y146	415	41	frameworks	framework	NNS
cord-024061-gxv8y146	415	42	of	of	IN
cord-024061-gxv8y146	415	43	ancestral	ancestral	JJ
cord-024061-gxv8y146	415	44	state	state	NN
cord-024061-gxv8y146	415	45	reconstruction	reconstruction	NN
cord-024061-gxv8y146	415	46	Improving	improve	VBG
cord-024061-gxv8y146	415	47	bayesian	bayesian	JJ
cord-024061-gxv8y146	415	48	population	population	NN
cord-024061-gxv8y146	415	49	dynamics	dynamic	NNS
cord-024061-gxv8y146	415	50	inference	inference	NN
cord-024061-gxv8y146	415	51	:	:	:
cord-024061-gxv8y146	415	52	a	a	DT
cord-024061-gxv8y146	415	53	coalescent	coalescent	NN
cord-024061-gxv8y146	415	54	-	-	HYPH
cord-024061-gxv8y146	415	55	based	base	VBN
cord-024061-gxv8y146	415	56	model	model	NN
cord-024061-gxv8y146	415	57	for	for	IN
cord-024061-gxv8y146	415	58	multiple	multiple	JJ
cord-024061-gxv8y146	415	59	loci	locus	NNS
cord-024061-gxv8y146	415	60	Real	real	JJ
cord-024061-gxv8y146	415	61	-	-	HYPH
cord-024061-gxv8y146	415	62	time	time	NN
cord-024061-gxv8y146	415	63	characterization	characterization	NN
cord-024061-gxv8y146	415	64	of	of	IN
cord-024061-gxv8y146	415	65	the	the	DT
cord-024061-gxv8y146	415	66	molecular	molecular	JJ
cord-024061-gxv8y146	415	67	epidemiology	epidemiology	NN
cord-024061-gxv8y146	415	68	of	of	IN
cord-024061-gxv8y146	415	69	an	an	DT
cord-024061-gxv8y146	415	70	influenza	influenza	NN
cord-024061-gxv8y146	415	71	pandemic	pandemic	JJ
cord-024061-gxv8y146	415	72	Reassortment	Reassortment	NNP
cord-024061-gxv8y146	415	73	patterns	pattern	NNS
cord-024061-gxv8y146	415	74	of	of	IN
cord-024061-gxv8y146	415	75	avian	avian	JJ
cord-024061-gxv8y146	415	76	influenza	influenza	NN
cord-024061-gxv8y146	415	77	virus	virus	NN
cord-024061-gxv8y146	415	78	internal	internal	JJ
cord-024061-gxv8y146	415	79	segments	segment	NNS
cord-024061-gxv8y146	415	80	among	among	IN
cord-024061-gxv8y146	415	81	different	different	JJ
cord-024061-gxv8y146	415	82	subtypes	subtype	NNS
cord-024061-gxv8y146	416	1	Avian	avian	JJ
cord-024061-gxv8y146	416	2	influenza	influenza	NN
cord-024061-gxv8y146	416	3	virus	virus	NN
cord-024061-gxv8y146	416	4	exhibits	exhibit	VBZ
cord-024061-gxv8y146	416	5	distinct	distinct	JJ
cord-024061-gxv8y146	416	6	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	416	7	dynamics	dynamic	NNS
cord-024061-gxv8y146	416	8	in	in	IN
cord-024061-gxv8y146	416	9	wild	wild	JJ
cord-024061-gxv8y146	416	10	birds	bird	NNS
cord-024061-gxv8y146	416	11	and	and	CC
cord-024061-gxv8y146	416	12	poultry	poultry	NN
cord-024061-gxv8y146	416	13	Applications	Applications	NNPS
cord-024061-gxv8y146	416	14	of	of	IN
cord-024061-gxv8y146	416	15	bayesian	bayesian	JJ
cord-024061-gxv8y146	416	16	phylodynamic	phylodynamic	NNP
cord-024061-gxv8y146	416	17	methods	method	NNS
cord-024061-gxv8y146	416	18	in	in	IN
cord-024061-gxv8y146	416	19	a	a	DT
cord-024061-gxv8y146	416	20	recent	recent	JJ
cord-024061-gxv8y146	416	21	porcine	porcine	JJ
cord-024061-gxv8y146	416	22	reproductive	reproductive	JJ
cord-024061-gxv8y146	416	23	US	US	NNP
cord-024061-gxv8y146	416	24	.	.	.
cord-024061-gxv8y146	417	1	and	and	CC
cord-024061-gxv8y146	417	2	respiratory	respiratory	JJ
cord-024061-gxv8y146	417	3	syndrome	syndrome	NN
cord-024061-gxv8y146	417	4	virus	virus	NN
cord-024061-gxv8y146	417	5	outbreak	outbreak	NN
cord-024061-gxv8y146	417	6	HIV	HIV	NNP
cord-024061-gxv8y146	417	7	epidemiology	epidemiology	NN
cord-024061-gxv8y146	417	8	.	.	.
cord-024061-gxv8y146	418	1	the	the	DT
cord-024061-gxv8y146	418	2	early	early	JJ
cord-024061-gxv8y146	418	3	spread	spread	NN
cord-024061-gxv8y146	418	4	and	and	CC
cord-024061-gxv8y146	418	5	epidemic	epidemic	NN
cord-024061-gxv8y146	418	6	ignition	ignition	NN
cord-024061-gxv8y146	418	7	of	of	IN
cord-024061-gxv8y146	418	8	HIV−1	HIV−1	NNP
cord-024061-gxv8y146	418	9	in	in	IN
cord-024061-gxv8y146	418	10	human	human	JJ
cord-024061-gxv8y146	418	11	populations	population	NNS
cord-024061-gxv8y146	418	12	Reconstruction	Reconstruction	NNP
cord-024061-gxv8y146	418	13	of	of	IN
cord-024061-gxv8y146	418	14	the	the	DT
cord-024061-gxv8y146	418	15	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	418	16	dynamics	dynamic	NNS
cord-024061-gxv8y146	418	17	of	of	IN
cord-024061-gxv8y146	418	18	the	the	DT
cord-024061-gxv8y146	418	19	A(H1N1)pdm09	A(H1N1)pdm09	NNP
cord-024061-gxv8y146	418	20	influenza	influenza	NN
cord-024061-gxv8y146	418	21	virus	virus	NN
cord-024061-gxv8y146	418	22	in	in	IN
cord-024061-gxv8y146	418	23	Italy	Italy	NNP
cord-024061-gxv8y146	418	24	during	during	IN
cord-024061-gxv8y146	418	25	the	the	DT
cord-024061-gxv8y146	418	26	pandemic	pandemic	NN
cord-024061-gxv8y146	418	27	and	and	CC
cord-024061-gxv8y146	418	28	post	post	JJ
cord-024061-gxv8y146	418	29	-	-	JJ
cord-024061-gxv8y146	418	30	pandemic	pandemic	JJ
cord-024061-gxv8y146	418	31	phases	phase	NNS
cord-024061-gxv8y146	418	32	Influenza	Influenza	NNP
cord-024061-gxv8y146	418	33	A	A	NNP
cord-024061-gxv8y146	418	34	Virus	virus	NN
cord-024061-gxv8y146	418	35	in	in	IN
cord-024061-gxv8y146	418	36	Swine	Swine	NNP
cord-024061-gxv8y146	418	37	Surveillance	Surveillance	NNP
cord-024061-gxv8y146	418	38	Origins	Origins	NNPS
cord-024061-gxv8y146	418	39	and	and	CC
cord-024061-gxv8y146	418	40	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	418	41	genomics	genomic	NNS
cord-024061-gxv8y146	418	42	of	of	IN
cord-024061-gxv8y146	418	43	the	the	DT
cord-024061-gxv8y146	418	44	2009	2009	CD
cord-024061-gxv8y146	418	45	swine	swine	NN
cord-024061-gxv8y146	418	46	-	-	HYPH
cord-024061-gxv8y146	418	47	origin	origin	NN
cord-024061-gxv8y146	418	48	H1N1	H1N1	NNP
cord-024061-gxv8y146	418	49	influenza	influenza	NN
cord-024061-gxv8y146	418	50	A	a	DT
cord-024061-gxv8y146	418	51	epidemic	epidemic	NN
cord-024061-gxv8y146	418	52	Phylogenomics	Phylogenomics	NNP
cord-024061-gxv8y146	418	53	and	and	CC
cord-024061-gxv8y146	418	54	molecular	molecular	JJ
cord-024061-gxv8y146	418	55	evolution	evolution	NN
cord-024061-gxv8y146	418	56	of	of	IN
cord-024061-gxv8y146	418	57	foot	foot	NN
cord-024061-gxv8y146	418	58	-	-	HYPH
cord-024061-gxv8y146	418	59	and	and	CC
cord-024061-gxv8y146	418	60	-	-	HYPH
cord-024061-gxv8y146	418	61	mouth	mouth	NN
cord-024061-gxv8y146	418	62	disease	disease	NN
cord-024061-gxv8y146	418	63	virus	virus	NN
cord-024061-gxv8y146	418	64	Phylogeographic	Phylogeographic	NNP
cord-024061-gxv8y146	418	65	and	and	CC
cord-024061-gxv8y146	418	66	cross	cross	JJ
cord-024061-gxv8y146	418	67	-	-	JJ
cord-024061-gxv8y146	418	68	species	species	JJ
cord-024061-gxv8y146	418	69	transmission	transmission	NN
cord-024061-gxv8y146	418	70	dynamics	dynamic	NNS
cord-024061-gxv8y146	418	71	of	of	IN
cord-024061-gxv8y146	418	72	SAT1	SAT1	NNP
cord-024061-gxv8y146	418	73	and	and	CC
cord-024061-gxv8y146	418	74	SAT2	SAT2	NNP
cord-024061-gxv8y146	418	75	foot	foot	NN
cord-024061-gxv8y146	418	76	-	-	HYPH
cord-024061-gxv8y146	418	77	and	and	CC
cord-024061-gxv8y146	418	78	-	-	HYPH
cord-024061-gxv8y146	418	79	mouth	mouth	NN
cord-024061-gxv8y146	418	80	disease	disease	NN
cord-024061-gxv8y146	418	81	virus	virus	NN
cord-024061-gxv8y146	418	82	in	in	IN
cord-024061-gxv8y146	418	83	eastern	eastern	JJ
cord-024061-gxv8y146	418	84	Africa	Africa	NNP
cord-024061-gxv8y146	418	85	Spatiotemporal	Spatiotemporal	NNP
cord-024061-gxv8y146	418	86	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	418	87	epidemiology	epidemiology	NN
cord-024061-gxv8y146	418	88	of	of	IN
cord-024061-gxv8y146	418	89	H5N1	H5N1	NNP
cord-024061-gxv8y146	418	90	highly	highly	RB
cord-024061-gxv8y146	418	91	pathogenic	pathogenic	JJ
cord-024061-gxv8y146	418	92	avian	avian	JJ
cord-024061-gxv8y146	418	93	influenza	influenza	NN
cord-024061-gxv8y146	418	94	in	in	IN
cord-024061-gxv8y146	418	95	West	West	NNP
cord-024061-gxv8y146	418	96	Africa	Africa	NNP
cord-024061-gxv8y146	418	97	and	and	CC
cord-024061-gxv8y146	418	98	Nigeria	Nigeria	NNP
cord-024061-gxv8y146	418	99	Influenza	Influenza	NNP
cord-024061-gxv8y146	418	100	a	a	DT
cord-024061-gxv8y146	418	101	virus	virus	NN
cord-024061-gxv8y146	418	102	migration	migration	NN
cord-024061-gxv8y146	418	103	and	and	CC
cord-024061-gxv8y146	418	104	persistence	persistence	NN
cord-024061-gxv8y146	418	105	in	in	IN
cord-024061-gxv8y146	418	106	north	north	JJ
cord-024061-gxv8y146	418	107	american	american	JJ
cord-024061-gxv8y146	418	108	wild	wild	JJ
cord-024061-gxv8y146	418	109	birds	bird	NNS
cord-024061-gxv8y146	418	110	Alignment	Alignment	NNP
cord-024061-gxv8y146	418	111	uncertainty	uncertainty	NN
cord-024061-gxv8y146	418	112	and	and	CC
cord-024061-gxv8y146	418	113	genomic	genomic	JJ
cord-024061-gxv8y146	418	114	analysis	analysis	NN
cord-024061-gxv8y146	418	115	Multiple	multiple	JJ
cord-024061-gxv8y146	418	116	sequence	sequence	NN
cord-024061-gxv8y146	418	117	alignment	alignment	NN
cord-024061-gxv8y146	418	118	averaging	averaging	NN
cord-024061-gxv8y146	418	119	improves	improve	VBZ
cord-024061-gxv8y146	418	120	phylogeny	phylogeny	NN
cord-024061-gxv8y146	418	121	reconstruction	reconstruction	NN
cord-024061-gxv8y146	418	122	Clustal	Clustal	NNP
cord-024061-gxv8y146	418	123	W	W	NNP
cord-024061-gxv8y146	418	124	and	and	CC
cord-024061-gxv8y146	419	1	clustal	clustal	NNP
cord-024061-gxv8y146	419	2	X	X	NNP
cord-024061-gxv8y146	419	3	version	version	NN
cord-024061-gxv8y146	419	4	2.0	2.0	CD
cord-024061-gxv8y146	419	5	Coffee	Coffee	NNP
cord-024061-gxv8y146	419	6	:	:	:
cord-024061-gxv8y146	419	7	a	a	DT
cord-024061-gxv8y146	419	8	novel	novel	JJ
cord-024061-gxv8y146	419	9	method	method	NN
cord-024061-gxv8y146	419	10	for	for	IN
cord-024061-gxv8y146	419	11	fast	fast	JJ
cord-024061-gxv8y146	419	12	and	and	CC
cord-024061-gxv8y146	419	13	accurate	accurate	JJ
cord-024061-gxv8y146	419	14	multiple	multiple	JJ
cord-024061-gxv8y146	419	15	sequence	sequence	NN
cord-024061-gxv8y146	419	16	alignment	alignment	NN
cord-024061-gxv8y146	419	17	MUSCLE	muscle	NN
cord-024061-gxv8y146	419	18	:	:	:
cord-024061-gxv8y146	419	19	multiple	multiple	JJ
cord-024061-gxv8y146	419	20	sequence	sequence	NN
cord-024061-gxv8y146	419	21	alignment	alignment	NN
cord-024061-gxv8y146	419	22	with	with	IN
cord-024061-gxv8y146	419	23	high	high	JJ
cord-024061-gxv8y146	419	24	accuracy	accuracy	NN
cord-024061-gxv8y146	419	25	and	and	CC
cord-024061-gxv8y146	419	26	high	high	JJ
cord-024061-gxv8y146	419	27	throughput	throughput	NN
cord-024061-gxv8y146	419	28	AliView	AliView	NNP
cord-024061-gxv8y146	419	29	:	:	:
cord-024061-gxv8y146	419	30	a	a	DT
cord-024061-gxv8y146	419	31	fast	fast	JJ
cord-024061-gxv8y146	419	32	and	and	CC
cord-024061-gxv8y146	419	33	lightweight	lightweight	JJ
cord-024061-gxv8y146	419	34	alignment	alignment	NN
cord-024061-gxv8y146	419	35	viewer	viewer	NN
cord-024061-gxv8y146	419	36	and	and	CC
cord-024061-gxv8y146	419	37	editor	editor	NN
cord-024061-gxv8y146	419	38	for	for	IN
cord-024061-gxv8y146	419	39	large	large	JJ
cord-024061-gxv8y146	419	40	datasets	dataset	NNS
cord-024061-gxv8y146	419	41	Evolutionary	evolutionary	JJ
cord-024061-gxv8y146	419	42	trees	tree	NNS
cord-024061-gxv8y146	419	43	from	from	IN
cord-024061-gxv8y146	419	44	DNA	dna	NN
cord-024061-gxv8y146	419	45	sequences	sequence	NNS
cord-024061-gxv8y146	419	46	:	:	:
cord-024061-gxv8y146	419	47	a	a	DT
cord-024061-gxv8y146	419	48	maximum	maximum	JJ
cord-024061-gxv8y146	419	49	likelihood	likelihood	NN
cord-024061-gxv8y146	419	50	approach	approach	NN
cord-024061-gxv8y146	419	51	Methods	method	NNS
cord-024061-gxv8y146	419	52	for	for	IN
cord-024061-gxv8y146	419	53	computing	compute	VBG
cord-024061-gxv8y146	419	54	wagner	wagner	NNP
cord-024061-gxv8y146	419	55	trees	tree	NNS
cord-024061-gxv8y146	420	1	The	the	DT
cord-024061-gxv8y146	420	2	neighbor	neighbor	NN
cord-024061-gxv8y146	420	3	-	-	HYPH
cord-024061-gxv8y146	420	4	joining	join	VBG
cord-024061-gxv8y146	420	5	method	method	NN
cord-024061-gxv8y146	420	6	:	:	:
cord-024061-gxv8y146	420	7	a	a	DT
cord-024061-gxv8y146	420	8	new	new	JJ
cord-024061-gxv8y146	420	9	method	method	NN
cord-024061-gxv8y146	420	10	for	for	IN
cord-024061-gxv8y146	420	11	reconstructing	reconstruct	VBG
cord-024061-gxv8y146	420	12	phylogenetic	phylogenetic	JJ
cord-024061-gxv8y146	420	13	trees	tree	NNS
cord-024061-gxv8y146	420	14	Building	build	VBG
cord-024061-gxv8y146	420	15	phylogenetic	phylogenetic	JJ
cord-024061-gxv8y146	420	16	trees	tree	NNS
cord-024061-gxv8y146	420	17	from	from	IN
cord-024061-gxv8y146	420	18	molecular	molecular	JJ
cord-024061-gxv8y146	420	19	data	datum	NNS
cord-024061-gxv8y146	420	20	with	with	IN
cord-024061-gxv8y146	420	21	MEGA	MEGA	NNP
cord-024061-gxv8y146	420	22	RAxML	RAxML	NNP
cord-024061-gxv8y146	420	23	version	version	NN
cord-024061-gxv8y146	420	24	8	8	CD
cord-024061-gxv8y146	420	25	:	:	:
cord-024061-gxv8y146	420	26	a	a	DT
cord-024061-gxv8y146	420	27	tool	tool	NN
cord-024061-gxv8y146	420	28	for	for	IN
cord-024061-gxv8y146	420	29	phylogenetic	phylogenetic	JJ
cord-024061-gxv8y146	420	30	analysis	analysis	NN
cord-024061-gxv8y146	420	31	and	and	CC
cord-024061-gxv8y146	420	32	post	post	NN
cord-024061-gxv8y146	420	33	-	-	NN
cord-024061-gxv8y146	420	34	analysis	analysis	NN
cord-024061-gxv8y146	420	35	of	of	IN
cord-024061-gxv8y146	420	36	large	large	JJ
cord-024061-gxv8y146	420	37	phylogenies	phylogeny	NNS
cord-024061-gxv8y146	421	1	The	the	DT
cord-024061-gxv8y146	421	2	phylogeography	phylogeography	NN
cord-024061-gxv8y146	421	3	of	of	IN
cord-024061-gxv8y146	421	4	human	human	JJ
cord-024061-gxv8y146	421	5	viruses	virus	NNS
cord-024061-gxv8y146	422	1	Treemmer	Treemmer	NNP
cord-024061-gxv8y146	422	2	:	:	:
cord-024061-gxv8y146	422	3	a	a	DT
cord-024061-gxv8y146	422	4	tool	tool	NN
cord-024061-gxv8y146	422	5	to	to	TO
cord-024061-gxv8y146	422	6	reduce	reduce	VB
cord-024061-gxv8y146	422	7	large	large	JJ
cord-024061-gxv8y146	422	8	phylogenetic	phylogenetic	JJ
cord-024061-gxv8y146	422	9	datasets	dataset	NNS
cord-024061-gxv8y146	422	10	with	with	IN
cord-024061-gxv8y146	422	11	minimal	minimal	JJ
cord-024061-gxv8y146	422	12	loss	loss	NN
cord-024061-gxv8y146	422	13	of	of	IN
cord-024061-gxv8y146	422	14	diversity	diversity	NN
cord-024061-gxv8y146	422	15	Recombination	Recombination	NNP
cord-024061-gxv8y146	422	16	in	in	IN
cord-024061-gxv8y146	422	17	viruses	virus	NNS
cord-024061-gxv8y146	422	18	:	:	:
cord-024061-gxv8y146	422	19	mechanisms	mechanism	NNS
cord-024061-gxv8y146	422	20	,	,	,
cord-024061-gxv8y146	422	21	methods	method	NNS
cord-024061-gxv8y146	422	22	of	of	IN
cord-024061-gxv8y146	422	23	study	study	NN
cord-024061-gxv8y146	422	24	,	,	,
cord-024061-gxv8y146	422	25	and	and	CC
cord-024061-gxv8y146	422	26	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	422	27	consequences	consequence	NNS
cord-024061-gxv8y146	423	1	Consequences	consequence	NNS
cord-024061-gxv8y146	423	2	of	of	IN
cord-024061-gxv8y146	423	3	recombination	recombination	NN
cord-024061-gxv8y146	423	4	on	on	IN
cord-024061-gxv8y146	423	5	traditional	traditional	JJ
cord-024061-gxv8y146	423	6	phylogenetic	phylogenetic	JJ
cord-024061-gxv8y146	423	7	analysis	analysis	NN
cord-024061-gxv8y146	424	1	RDP3	rdp3	NN
cord-024061-gxv8y146	424	2	:	:	:
cord-024061-gxv8y146	424	3	a	a	DT
cord-024061-gxv8y146	424	4	flexible	flexible	JJ
cord-024061-gxv8y146	424	5	and	and	CC
cord-024061-gxv8y146	424	6	fast	fast	JJ
cord-024061-gxv8y146	424	7	computer	computer	NN
cord-024061-gxv8y146	424	8	program	program	NN
cord-024061-gxv8y146	424	9	for	for	IN
cord-024061-gxv8y146	424	10	analyzing	analyze	VBG
cord-024061-gxv8y146	424	11	recombination	recombination	NN
cord-024061-gxv8y146	424	12	Exploring	explore	VBG
cord-024061-gxv8y146	424	13	the	the	DT
cord-024061-gxv8y146	424	14	temporal	temporal	JJ
cord-024061-gxv8y146	424	15	structure	structure	NN
cord-024061-gxv8y146	424	16	of	of	IN
cord-024061-gxv8y146	424	17	heterochronous	heterochronous	JJ
cord-024061-gxv8y146	424	18	sequences	sequence	NNS
cord-024061-gxv8y146	424	19	using	use	VBG
cord-024061-gxv8y146	424	20	tempEst	tempEst	.
cord-024061-gxv8y146	424	21	(	(	-LRB-
cord-024061-gxv8y146	425	1	formerly	formerly	RB
cord-024061-gxv8y146	425	2	path	path	NN
cord-024061-gxv8y146	425	3	-	-	HYPH
cord-024061-gxv8y146	425	4	O	o	NN
cord-024061-gxv8y146	425	5	-	-	HYPH
cord-024061-gxv8y146	425	6	Gen	gen	NN
cord-024061-gxv8y146	425	7	)	)	-RRB-
cord-024061-gxv8y146	425	8	Measurably	measurably	RB
cord-024061-gxv8y146	425	9	evolving	evolve	VBG
cord-024061-gxv8y146	425	10	populations	population	NNS
cord-024061-gxv8y146	425	11	Substitution	substitution	NN
cord-024061-gxv8y146	425	12	and	and	CC
cord-024061-gxv8y146	425	13	site	site	NN
cord-024061-gxv8y146	425	14	models	model	NNS
cord-024061-gxv8y146	426	1	Fast	fast	RB
cord-024061-gxv8y146	426	2	,	,	,
cord-024061-gxv8y146	426	3	accurate	accurate	JJ
cord-024061-gxv8y146	426	4	and	and	CC
cord-024061-gxv8y146	426	5	simulation	simulation	NN
cord-024061-gxv8y146	426	6	-	-	HYPH
cord-024061-gxv8y146	426	7	free	free	JJ
cord-024061-gxv8y146	426	8	stochastic	stochastic	JJ
cord-024061-gxv8y146	426	9	mapping	mapping	NN
cord-024061-gxv8y146	426	10	Dating	Dating	NNP
cord-024061-gxv8y146	426	11	of	of	IN
cord-024061-gxv8y146	426	12	the	the	DT
cord-024061-gxv8y146	426	13	human	human	JJ
cord-024061-gxv8y146	426	14	-	-	HYPH
cord-024061-gxv8y146	426	15	ape	ape	NN
cord-024061-gxv8y146	426	16	splitting	splitting	NN
cord-024061-gxv8y146	426	17	by	by	IN
cord-024061-gxv8y146	426	18	a	a	DT
cord-024061-gxv8y146	426	19	molecular	molecular	JJ
cord-024061-gxv8y146	426	20	clock	clock	NN
cord-024061-gxv8y146	426	21	of	of	IN
cord-024061-gxv8y146	426	22	mitochondrial	mitochondrial	JJ
cord-024061-gxv8y146	426	23	DNA	dna	NN
cord-024061-gxv8y146	427	1	Some	some	DT
cord-024061-gxv8y146	427	2	probabilistic	probabilistic	JJ
cord-024061-gxv8y146	427	3	and	and	CC
cord-024061-gxv8y146	427	4	statistical	statistical	JJ
cord-024061-gxv8y146	427	5	problems	problem	NNS
cord-024061-gxv8y146	427	6	in	in	IN
cord-024061-gxv8y146	427	7	the	the	DT
cord-024061-gxv8y146	427	8	analysis	analysis	NN
cord-024061-gxv8y146	427	9	of	of	IN
cord-024061-gxv8y146	427	10	DNA	dna	NN
cord-024061-gxv8y146	427	11	sequences	sequence	NNS
cord-024061-gxv8y146	428	1	Maximum	maximum	JJ
cord-024061-gxv8y146	428	2	likelihood	likelihood	NN
cord-024061-gxv8y146	428	3	phylogenetic	phylogenetic	JJ
cord-024061-gxv8y146	428	4	estimation	estimation	NN
cord-024061-gxv8y146	428	5	from	from	IN
cord-024061-gxv8y146	428	6	DNA	dna	NN
cord-024061-gxv8y146	428	7	sequences	sequence	NNS
cord-024061-gxv8y146	428	8	with	with	IN
cord-024061-gxv8y146	428	9	variable	variable	JJ
cord-024061-gxv8y146	428	10	rates	rate	NNS
cord-024061-gxv8y146	428	11	over	over	IN
cord-024061-gxv8y146	428	12	sites	site	NNS
cord-024061-gxv8y146	428	13	:	:	:
cord-024061-gxv8y146	429	1	approximate	approximate	JJ
cord-024061-gxv8y146	429	2	methods	method	NNS
cord-024061-gxv8y146	430	1	Maximum	maximum	JJ
cord-024061-gxv8y146	430	2	likelihood	likelihood	NN
cord-024061-gxv8y146	430	3	estimation	estimation	NN
cord-024061-gxv8y146	430	4	of	of	IN
cord-024061-gxv8y146	430	5	the	the	DT
cord-024061-gxv8y146	430	6	heterogeneity	heterogeneity	NN
cord-024061-gxv8y146	430	7	of	of	IN
cord-024061-gxv8y146	430	8	substitution	substitution	NN
cord-024061-gxv8y146	430	9	rate	rate	NN
cord-024061-gxv8y146	430	10	among	among	IN
cord-024061-gxv8y146	430	11	nucleotide	nucleotide	JJ
cord-024061-gxv8y146	430	12	sites	site	NNS
cord-024061-gxv8y146	431	1	An	an	DT
cord-024061-gxv8y146	431	2	empirical	empirical	JJ
cord-024061-gxv8y146	431	3	examination	examination	NN
cord-024061-gxv8y146	431	4	of	of	IN
cord-024061-gxv8y146	431	5	the	the	DT
cord-024061-gxv8y146	431	6	utility	utility	NN
cord-024061-gxv8y146	431	7	of	of	IN
cord-024061-gxv8y146	431	8	codon	codon	NN
cord-024061-gxv8y146	431	9	-	-	HYPH
cord-024061-gxv8y146	431	10	substitution	substitution	NN
cord-024061-gxv8y146	431	11	models	model	NNS
cord-024061-gxv8y146	431	12	in	in	IN
cord-024061-gxv8y146	431	13	phylogeny	phylogeny	NN
cord-024061-gxv8y146	431	14	reconstruction	reconstruction	NN
cord-024061-gxv8y146	431	15	Maximum	maximum	NN
cord-024061-gxv8y146	431	16	-	-	HYPH
cord-024061-gxv8y146	431	17	likelihood	likelihood	NN
cord-024061-gxv8y146	431	18	models	model	NNS
cord-024061-gxv8y146	431	19	for	for	IN
cord-024061-gxv8y146	431	20	combined	combined	JJ
cord-024061-gxv8y146	431	21	analyses	analysis	NNS
cord-024061-gxv8y146	431	22	of	of	IN
cord-024061-gxv8y146	431	23	multiple	multiple	JJ
cord-024061-gxv8y146	431	24	sequence	sequence	NN
cord-024061-gxv8y146	431	25	data	datum	NNS
cord-024061-gxv8y146	431	26	Likelihood	likelihood	NN
cord-024061-gxv8y146	431	27	ratio	ratio	NN
cord-024061-gxv8y146	431	28	tests	test	NNS
cord-024061-gxv8y146	431	29	for	for	IN
cord-024061-gxv8y146	431	30	detecting	detect	VBG
cord-024061-gxv8y146	431	31	positive	positive	JJ
cord-024061-gxv8y146	431	32	selection	selection	NN
cord-024061-gxv8y146	431	33	and	and	CC
cord-024061-gxv8y146	431	34	application	application	NN
cord-024061-gxv8y146	431	35	to	to	IN
cord-024061-gxv8y146	431	36	primate	primate	JJ
cord-024061-gxv8y146	431	37	lysozyme	lysozyme	NNS
cord-024061-gxv8y146	431	38	evolution	evolution	NN
cord-024061-gxv8y146	431	39	Estimating	estimate	VBG
cord-024061-gxv8y146	431	40	the	the	DT
cord-024061-gxv8y146	431	41	dimension	dimension	NN
cord-024061-gxv8y146	431	42	of	of	IN
cord-024061-gxv8y146	431	43	a	a	DT
cord-024061-gxv8y146	431	44	model	model	NN
cord-024061-gxv8y146	431	45	Regression	regression	NN
cord-024061-gxv8y146	431	46	and	and	CC
cord-024061-gxv8y146	431	47	time	time	NNP
cord-024061-gxv8y146	431	48	series	series	NN
cord-024061-gxv8y146	431	49	model	model	NN
cord-024061-gxv8y146	431	50	selection	selection	NN
cord-024061-gxv8y146	431	51	in	in	IN
cord-024061-gxv8y146	431	52	small	small	JJ
cord-024061-gxv8y146	431	53	samples	sample	NNS
cord-024061-gxv8y146	431	54	Methods	method	NNS
cord-024061-gxv8y146	431	55	for	for	IN
cord-024061-gxv8y146	431	56	selecting	select	VBG
cord-024061-gxv8y146	431	57	fixedeffect	fixedeffect	NN
cord-024061-gxv8y146	431	58	models	model	NNS
cord-024061-gxv8y146	431	59	for	for	IN
cord-024061-gxv8y146	431	60	heterogeneous	heterogeneous	JJ
cord-024061-gxv8y146	431	61	codon	codon	NN
cord-024061-gxv8y146	431	62	evolution	evolution	NN
cord-024061-gxv8y146	431	63	,	,	,
cord-024061-gxv8y146	431	64	with	with	IN
cord-024061-gxv8y146	431	65	comments	comment	NNS
cord-024061-gxv8y146	431	66	on	on	IN
cord-024061-gxv8y146	431	67	their	-PRON-	PRP$
cord-024061-gxv8y146	431	68	application	application	NN
cord-024061-gxv8y146	431	69	to	to	TO
cord-024061-gxv8y146	431	70	gene	gene	NN
cord-024061-gxv8y146	431	71	and	and	CC
cord-024061-gxv8y146	431	72	genome	genome	NN
cord-024061-gxv8y146	431	73	data	datum	NNS
cord-024061-gxv8y146	431	74	Partitionfinder	Partitionfinder	NNP
cord-024061-gxv8y146	431	75	:	:	:
cord-024061-gxv8y146	431	76	combined	combine	VBN
cord-024061-gxv8y146	431	77	selection	selection	NN
cord-024061-gxv8y146	431	78	of	of	IN
cord-024061-gxv8y146	431	79	partitioning	partitioning	NN
cord-024061-gxv8y146	431	80	schemes	scheme	NNS
cord-024061-gxv8y146	431	81	and	and	CC
cord-024061-gxv8y146	431	82	substitution	substitution	NN
cord-024061-gxv8y146	431	83	models	model	NNS
cord-024061-gxv8y146	431	84	for	for	IN
cord-024061-gxv8y146	431	85	phylogenetic	phylogenetic	JJ
cord-024061-gxv8y146	431	86	analyses	analysis	NNS
cord-024061-gxv8y146	431	87	ModelTest	ModelTest	NNP
cord-024061-gxv8y146	431	88	2	2	CD
cord-024061-gxv8y146	431	89	:	:	:
cord-024061-gxv8y146	431	90	more	more	JJR
cord-024061-gxv8y146	431	91	models	model	NNS
cord-024061-gxv8y146	431	92	,	,	,
cord-024061-gxv8y146	431	93	new	new	JJ
cord-024061-gxv8y146	431	94	heuristics	heuristic	NNS
cord-024061-gxv8y146	431	95	and	and	CC
cord-024061-gxv8y146	431	96	parallel	parallel	JJ
cord-024061-gxv8y146	431	97	computing	computing	NN
cord-024061-gxv8y146	431	98	bModelTest	bmodeltest	NN
cord-024061-gxv8y146	431	99	:	:	:
cord-024061-gxv8y146	432	1	Bayesian	bayesian	JJ
cord-024061-gxv8y146	432	2	phylogenetic	phylogenetic	NN
cord-024061-gxv8y146	432	3	site	site	NN
cord-024061-gxv8y146	432	4	model	model	NN
cord-024061-gxv8y146	432	5	averaging	averaging	NN
cord-024061-gxv8y146	432	6	and	and	CC
cord-024061-gxv8y146	432	7	model	model	NN
cord-024061-gxv8y146	432	8	comparison	comparison	NN
cord-024061-gxv8y146	433	1	The	the	DT
cord-024061-gxv8y146	433	2	molecular	molecular	JJ
cord-024061-gxv8y146	433	3	clock	clock	NN
cord-024061-gxv8y146	433	4	Divergence	divergence	NN
cord-024061-gxv8y146	433	5	time	time	NN
cord-024061-gxv8y146	433	6	and	and	CC
cord-024061-gxv8y146	433	7	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	433	8	rate	rate	NN
cord-024061-gxv8y146	433	9	estimation	estimation	NN
cord-024061-gxv8y146	433	10	with	with	IN
cord-024061-gxv8y146	433	11	multilocus	multilocus	NNP
cord-024061-gxv8y146	433	12	data	datum	NNS
cord-024061-gxv8y146	433	13	Relaxed	relaxed	JJ
cord-024061-gxv8y146	433	14	phylogenetics	phylogenetic	NNS
cord-024061-gxv8y146	433	15	and	and	CC
cord-024061-gxv8y146	433	16	dating	date	VBG
cord-024061-gxv8y146	433	17	with	with	IN
cord-024061-gxv8y146	433	18	confidence	confidence	NN
cord-024061-gxv8y146	433	19	Estimation	estimation	NN
cord-024061-gxv8y146	433	20	of	of	IN
cord-024061-gxv8y146	433	21	the	the	DT
cord-024061-gxv8y146	433	22	transition	transition	NN
cord-024061-gxv8y146	433	23	/	/	SYM
cord-024061-gxv8y146	433	24	transversion	transversion	NN
cord-024061-gxv8y146	433	25	rate	rate	NN
cord-024061-gxv8y146	433	26	bias	bias	NN
cord-024061-gxv8y146	433	27	and	and	CC
cord-024061-gxv8y146	433	28	species	species	NN
cord-024061-gxv8y146	433	29	sampling	sample	VBG
cord-024061-gxv8y146	433	30	Bayesian	Bayesian	NNP
cord-024061-gxv8y146	433	31	random	random	JJ
cord-024061-gxv8y146	433	32	local	local	JJ
cord-024061-gxv8y146	433	33	clocks	clock	NNS
cord-024061-gxv8y146	433	34	,	,	,
cord-024061-gxv8y146	433	35	or	or	CC
cord-024061-gxv8y146	433	36	one	one	CD
cord-024061-gxv8y146	433	37	rate	rate	NN
cord-024061-gxv8y146	433	38	to	to	TO
cord-024061-gxv8y146	433	39	rule	rule	VB
cord-024061-gxv8y146	433	40	them	-PRON-	PRP
cord-024061-gxv8y146	433	41	all	all	DT
cord-024061-gxv8y146	433	42	Evolutionary	evolutionary	JJ
cord-024061-gxv8y146	433	43	trees	tree	NNS
cord-024061-gxv8y146	434	1	On	on	IN
cord-024061-gxv8y146	434	2	the	the	DT
cord-024061-gxv8y146	434	3	genealogy	genealogy	NN
cord-024061-gxv8y146	434	4	of	of	IN
cord-024061-gxv8y146	434	5	large	large	JJ
cord-024061-gxv8y146	434	6	populations	population	NNS
cord-024061-gxv8y146	434	7	Estimating	estimate	VBG
cord-024061-gxv8y146	434	8	effective	effective	JJ
cord-024061-gxv8y146	434	9	population	population	NN
cord-024061-gxv8y146	434	10	size	size	NN
cord-024061-gxv8y146	434	11	and	and	CC
cord-024061-gxv8y146	434	12	mutation	mutation	NN
cord-024061-gxv8y146	434	13	rate	rate	NN
cord-024061-gxv8y146	434	14	from	from	IN
cord-024061-gxv8y146	434	15	sequence	sequence	NN
cord-024061-gxv8y146	434	16	data	datum	NNS
cord-024061-gxv8y146	434	17	using	use	VBG
cord-024061-gxv8y146	434	18	Metropolis	Metropolis	NNP
cord-024061-gxv8y146	434	19	-	-	HYPH
cord-024061-gxv8y146	434	20	hastings	hastings	NNP
cord-024061-gxv8y146	434	21	sampling	sampling	NN
cord-024061-gxv8y146	434	22	Estimating	Estimating	NNP
cord-024061-gxv8y146	434	23	mutation	mutation	NN
cord-024061-gxv8y146	434	24	parameters	parameter	NNS
cord-024061-gxv8y146	434	25	,	,	,
cord-024061-gxv8y146	434	26	population	population	NN
cord-024061-gxv8y146	434	27	history	history	NN
cord-024061-gxv8y146	434	28	and	and	CC
cord-024061-gxv8y146	434	29	genealogy	genealogy	NN
cord-024061-gxv8y146	434	30	simultaneously	simultaneously	RB
cord-024061-gxv8y146	434	31	from	from	IN
cord-024061-gxv8y146	434	32	temporally	temporally	RB
cord-024061-gxv8y146	434	33	spaced	space	VBN
cord-024061-gxv8y146	434	34	sequence	sequence	NN
cord-024061-gxv8y146	434	35	data	data	NN
cord-024061-gxv8y146	434	36	Maximum	maximum	NN
cord-024061-gxv8y146	434	37	-	-	HYPH
cord-024061-gxv8y146	434	38	likelihood	likelihood	NN
cord-024061-gxv8y146	434	39	estimation	estimation	NN
cord-024061-gxv8y146	434	40	of	of	IN
cord-024061-gxv8y146	434	41	migration	migration	NN
cord-024061-gxv8y146	434	42	rates	rate	NNS
cord-024061-gxv8y146	434	43	and	and	CC
cord-024061-gxv8y146	434	44	effective	effective	JJ
cord-024061-gxv8y146	434	45	population	population	NN
cord-024061-gxv8y146	434	46	numbers	number	NNS
cord-024061-gxv8y146	434	47	in	in	IN
cord-024061-gxv8y146	434	48	two	two	CD
cord-024061-gxv8y146	434	49	populations	population	NNS
cord-024061-gxv8y146	434	50	using	use	VBG
cord-024061-gxv8y146	434	51	a	a	DT
cord-024061-gxv8y146	434	52	coalescent	coalescent	JJ
cord-024061-gxv8y146	434	53	approach	approach	NN
cord-024061-gxv8y146	434	54	Unifying	unify	VBG
cord-024061-gxv8y146	434	55	vertical	vertical	JJ
cord-024061-gxv8y146	434	56	and	and	CC
cord-024061-gxv8y146	434	57	nonvertical	nonvertical	JJ
cord-024061-gxv8y146	434	58	evolution	evolution	NN
cord-024061-gxv8y146	434	59	:	:	:
cord-024061-gxv8y146	434	60	a	a	DT
cord-024061-gxv8y146	434	61	stochastic	stochastic	JJ
cord-024061-gxv8y146	434	62	ARG	arg	NN
cord-024061-gxv8y146	434	63	-	-	HYPH
cord-024061-gxv8y146	434	64	based	base	VBN
cord-024061-gxv8y146	434	65	framework	framework	NN
cord-024061-gxv8y146	434	66	A	a	DT
cord-024061-gxv8y146	434	67	viral	viral	JJ
cord-024061-gxv8y146	434	68	sampling	sampling	NN
cord-024061-gxv8y146	434	69	design	design	NN
cord-024061-gxv8y146	434	70	for	for	IN
cord-024061-gxv8y146	434	71	testing	test	VBG
cord-024061-gxv8y146	434	72	the	the	DT
cord-024061-gxv8y146	434	73	molecular	molecular	JJ
cord-024061-gxv8y146	434	74	clock	clock	NN
cord-024061-gxv8y146	434	75	and	and	CC
cord-024061-gxv8y146	434	76	for	for	IN
cord-024061-gxv8y146	434	77	estimating	estimate	VBG
cord-024061-gxv8y146	434	78	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	434	79	rates	rate	NNS
cord-024061-gxv8y146	434	80	and	and	CC
cord-024061-gxv8y146	434	81	divergence	divergence	NN
cord-024061-gxv8y146	434	82	times	time	NNS
cord-024061-gxv8y146	434	83	Ancestral	ancestral	JJ
cord-024061-gxv8y146	434	84	inference	inference	NN
cord-024061-gxv8y146	434	85	in	in	IN
cord-024061-gxv8y146	434	86	population	population	NN
cord-024061-gxv8y146	434	87	genetics	genetics	NN
cord-024061-gxv8y146	434	88	Phylodynamics	Phylodynamics	NNPS
cord-024061-gxv8y146	434	89	of	of	IN
cord-024061-gxv8y146	434	90	H5N1	H5N1	NNP
cord-024061-gxv8y146	434	91	highly	highly	RB
cord-024061-gxv8y146	434	92	pathogenic	pathogenic	JJ
cord-024061-gxv8y146	434	93	avian	avian	JJ
cord-024061-gxv8y146	434	94	influenza	influenza	NN
cord-024061-gxv8y146	434	95	in	in	IN
cord-024061-gxv8y146	434	96	europe	europe	NNP
cord-024061-gxv8y146	435	1	An	an	DT
cord-024061-gxv8y146	435	2	integrated	integrated	JJ
cord-024061-gxv8y146	435	3	framework	framework	NN
cord-024061-gxv8y146	435	4	for	for	IN
cord-024061-gxv8y146	435	5	the	the	DT
cord-024061-gxv8y146	435	6	inference	inference	NN
cord-024061-gxv8y146	435	7	of	of	IN
cord-024061-gxv8y146	435	8	viral	viral	JJ
cord-024061-gxv8y146	435	9	population	population	NN
cord-024061-gxv8y146	435	10	history	history	NN
cord-024061-gxv8y146	435	11	from	from	IN
cord-024061-gxv8y146	435	12	reconstructed	reconstruct	VBN
cord-024061-gxv8y146	435	13	genealogies	genealogy	NNS
cord-024061-gxv8y146	435	14	Bayesian	bayesian	JJ
cord-024061-gxv8y146	435	15	coalescent	coalescent	JJ
cord-024061-gxv8y146	435	16	inference	inference	NN
cord-024061-gxv8y146	435	17	of	of	IN
cord-024061-gxv8y146	435	18	past	past	JJ
cord-024061-gxv8y146	435	19	population	population	NN
cord-024061-gxv8y146	435	20	dynamics	dynamic	NNS
cord-024061-gxv8y146	435	21	from	from	IN
cord-024061-gxv8y146	435	22	molecular	molecular	JJ
cord-024061-gxv8y146	435	23	sequences	sequence	NNS
cord-024061-gxv8y146	435	24	Smooth	Smooth	NNP
cord-024061-gxv8y146	435	25	skyride	skyride	NN
cord-024061-gxv8y146	435	26	through	through	IN
cord-024061-gxv8y146	435	27	a	a	DT
cord-024061-gxv8y146	435	28	rough	rough	JJ
cord-024061-gxv8y146	435	29	skyline	skyline	NN
cord-024061-gxv8y146	435	30	:	:	:
cord-024061-gxv8y146	435	31	bayesian	bayesian	JJ
cord-024061-gxv8y146	435	32	coalescent	coalescent	NN
cord-024061-gxv8y146	435	33	-	-	HYPH
cord-024061-gxv8y146	435	34	based	base	VBN
cord-024061-gxv8y146	435	35	inference	inference	NN
cord-024061-gxv8y146	435	36	of	of	IN
cord-024061-gxv8y146	435	37	population	population	NN
cord-024061-gxv8y146	435	38	dynamics	dynamic	NNS
cord-024061-gxv8y146	435	39	Structured	structure	VBN
cord-024061-gxv8y146	435	40	trees	tree	NNS
cord-024061-gxv8y146	435	41	and	and	CC
cord-024061-gxv8y146	435	42	phylogeography	phylogeography	NN
cord-024061-gxv8y146	435	43	Bayesian	bayesian	JJ
cord-024061-gxv8y146	435	44	phylogeography	phylogeography	NN
cord-024061-gxv8y146	435	45	finds	find	VBZ
cord-024061-gxv8y146	435	46	its	-PRON-	PRP$
cord-024061-gxv8y146	435	47	roots	root	NNS
cord-024061-gxv8y146	435	48	Phylodynamics	phylodynamic	NNS
cord-024061-gxv8y146	435	49	and	and	CC
cord-024061-gxv8y146	435	50	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	435	51	epidemiology	epidemiology	NN
cord-024061-gxv8y146	435	52	of	of	IN
cord-024061-gxv8y146	435	53	african	african	JJ
cord-024061-gxv8y146	435	54	swine	swine	NN
cord-024061-gxv8y146	435	55	fever	fever	NN
cord-024061-gxv8y146	435	56	p72-CVR	p72-cvr	CD
cord-024061-gxv8y146	435	57	genes	gene	NNS
cord-024061-gxv8y146	435	58	in	in	IN
cord-024061-gxv8y146	435	59	Eurasia	Eurasia	NNP
cord-024061-gxv8y146	435	60	and	and	CC
cord-024061-gxv8y146	435	61	Africa	Africa	NNP
cord-024061-gxv8y146	435	62	Using	use	VBG
cord-024061-gxv8y146	435	63	temporally	temporally	RB
cord-024061-gxv8y146	435	64	spaced	space	VBN
cord-024061-gxv8y146	435	65	sequences	sequence	NNS
cord-024061-gxv8y146	435	66	to	to	TO
cord-024061-gxv8y146	435	67	simultaneously	simultaneously	RB
cord-024061-gxv8y146	435	68	estimate	estimate	VB
cord-024061-gxv8y146	435	69	migration	migration	NN
cord-024061-gxv8y146	435	70	rates	rate	NNS
cord-024061-gxv8y146	435	71	,	,	,
cord-024061-gxv8y146	435	72	mutation	mutation	NN
cord-024061-gxv8y146	435	73	rate	rate	NN
cord-024061-gxv8y146	435	74	and	and	CC
cord-024061-gxv8y146	435	75	population	population	NN
cord-024061-gxv8y146	435	76	sizes	size	NNS
cord-024061-gxv8y146	435	77	in	in	IN
cord-024061-gxv8y146	435	78	measurably	measurably	RB
cord-024061-gxv8y146	435	79	evolving	evolve	VBG
cord-024061-gxv8y146	435	80	populations	population	NNS
cord-024061-gxv8y146	435	81	SCOTTI	SCOTTI	NNP
cord-024061-gxv8y146	435	82	:	:	:
cord-024061-gxv8y146	435	83	efficient	efficient	JJ
cord-024061-gxv8y146	435	84	reconstruction	reconstruction	NN
cord-024061-gxv8y146	435	85	of	of	IN
cord-024061-gxv8y146	435	86	transmission	transmission	NN
cord-024061-gxv8y146	435	87	within	within	IN
cord-024061-gxv8y146	435	88	outbreaks	outbreak	NNS
cord-024061-gxv8y146	435	89	with	with	IN
cord-024061-gxv8y146	435	90	the	the	DT
cord-024061-gxv8y146	435	91	structured	structured	JJ
cord-024061-gxv8y146	435	92	coalescent	coalescent	NN
cord-024061-gxv8y146	435	93	MASCOT	mascot	NN
cord-024061-gxv8y146	435	94	:	:	:
cord-024061-gxv8y146	435	95	parameter	parameter	NN
cord-024061-gxv8y146	435	96	and	and	CC
cord-024061-gxv8y146	435	97	state	state	NN
cord-024061-gxv8y146	435	98	inference	inference	NN
cord-024061-gxv8y146	435	99	under	under	IN
cord-024061-gxv8y146	435	100	the	the	DT
cord-024061-gxv8y146	435	101	marginal	marginal	JJ
cord-024061-gxv8y146	435	102	structured	structured	JJ
cord-024061-gxv8y146	435	103	coalescent	coalescent	NN
cord-024061-gxv8y146	435	104	approximation	approximation	NN
cord-024061-gxv8y146	435	105	Phylodynamics	phylodynamic	NNS
cord-024061-gxv8y146	435	106	of	of	IN
cord-024061-gxv8y146	435	107	infectious	infectious	JJ
cord-024061-gxv8y146	435	108	disease	disease	NN
cord-024061-gxv8y146	435	109	epidemics	epidemic	NNS
cord-024061-gxv8y146	435	110	Modelling	model	VBG
cord-024061-gxv8y146	435	111	tree	tree	NN
cord-024061-gxv8y146	435	112	shape	shape	NN
cord-024061-gxv8y146	435	113	and	and	CC
cord-024061-gxv8y146	435	114	structure	structure	NN
cord-024061-gxv8y146	435	115	in	in	IN
cord-024061-gxv8y146	435	116	viral	viral	JJ
cord-024061-gxv8y146	435	117	phylodynamics	phylodynamic	NNS
cord-024061-gxv8y146	435	118	Using	use	VBG
cord-024061-gxv8y146	435	119	an	an	DT
cord-024061-gxv8y146	435	120	epidemiological	epidemiological	JJ
cord-024061-gxv8y146	435	121	model	model	NN
cord-024061-gxv8y146	435	122	for	for	IN
cord-024061-gxv8y146	435	123	phylogenetic	phylogenetic	JJ
cord-024061-gxv8y146	435	124	inference	inference	NN
cord-024061-gxv8y146	435	125	reveals	reveal	VBZ
cord-024061-gxv8y146	435	126	density	density	NN
cord-024061-gxv8y146	435	127	dependence	dependence	NN
cord-024061-gxv8y146	435	128	in	in	IN
cord-024061-gxv8y146	435	129	HIV	HIV	NNP
cord-024061-gxv8y146	435	130	transmission	transmission	NN
cord-024061-gxv8y146	435	131	Bayesian	Bayesian	NNP
cord-024061-gxv8y146	435	132	phylogenetics	phylogenetic	NNS
cord-024061-gxv8y146	435	133	with	with	IN
cord-024061-gxv8y146	435	134	BEAUti	BEAUti	NNP
cord-024061-gxv8y146	435	135	and	and	CC
cord-024061-gxv8y146	435	136	the	the	DT
cord-024061-gxv8y146	435	137	BEAST	BEAST	NNP
cord-024061-gxv8y146	435	138	1.7	1.7	CD
cord-024061-gxv8y146	435	139	Available	available	JJ
cord-024061-gxv8y146	435	140	online	online	RB
cord-024061-gxv8y146	435	141	at	at	IN
cord-024061-gxv8y146	435	142	Available	available	JJ
cord-024061-gxv8y146	435	143	online	online	RB
cord-024061-gxv8y146	435	144	at	at	IN
cord-024061-gxv8y146	435	145	Model	Model	NNP
cord-024061-gxv8y146	435	146	Selection	Selection	NNP
cord-024061-gxv8y146	435	147	Tutorial	Tutorial	NNP
cord-024061-gxv8y146	435	148	Choosing	choose	VBG
cord-024061-gxv8y146	435	149	among	among	IN
cord-024061-gxv8y146	435	150	partition	partition	NN
cord-024061-gxv8y146	435	151	models	model	NNS
cord-024061-gxv8y146	435	152	in	in	IN
cord-024061-gxv8y146	435	153	Bayesian	Bayesian	NNP
cord-024061-gxv8y146	435	154	Phylogenetics	Phylogenetics	NNP
cord-024061-gxv8y146	435	155	Posterior	Posterior	NNP
cord-024061-gxv8y146	435	156	analysis	analysis	NN
cord-024061-gxv8y146	435	157	and	and	CC
cord-024061-gxv8y146	435	158	post	post	NN
cord-024061-gxv8y146	435	159	processing	process	VBG
cord-024061-gxv8y146	435	160	Posterior	posterior	JJ
cord-024061-gxv8y146	435	161	summarization	summarization	NN
cord-024061-gxv8y146	435	162	in	in	IN
cord-024061-gxv8y146	435	163	Bayesian	Bayesian	NNP
cord-024061-gxv8y146	435	164	phylogenetics	phylogenetic	NNS
cord-024061-gxv8y146	435	165	using	use	VBG
cord-024061-gxv8y146	435	166	tracer	tracer	NN
cord-024061-gxv8y146	435	167	1.7	1.7	CD
cord-024061-gxv8y146	435	168	Should	Should	MD
cord-024061-gxv8y146	435	169	phylogenetic	phylogenetic	VB
cord-024061-gxv8y146	435	170	models	model	NNS
cord-024061-gxv8y146	435	171	be	be	VB
cord-024061-gxv8y146	435	172	trying	try	VBG
cord-024061-gxv8y146	435	173	to	to	TO
cord-024061-gxv8y146	435	174	"	"	``
cord-024061-gxv8y146	435	175	fit	fit	VB
cord-024061-gxv8y146	435	176	an	an	DT
cord-024061-gxv8y146	435	177	elephant	elephant	NN
cord-024061-gxv8y146	435	178	"	"	''
cord-024061-gxv8y146	435	179	?	?	.
cord-024061-gxv8y146	436	1	SpreaD3	SpreaD3	.
cord-024061-gxv8y146	437	1	:	:	:
cord-024061-gxv8y146	438	1	interactive	interactive	JJ
cord-024061-gxv8y146	438	2	visualization	visualization	NN
cord-024061-gxv8y146	438	3	of	of	IN
cord-024061-gxv8y146	438	4	spatiotemporal	spatiotemporal	JJ
cord-024061-gxv8y146	438	5	history	history	NN
cord-024061-gxv8y146	438	6	and	and	CC
cord-024061-gxv8y146	438	7	trait	trait	NN
cord-024061-gxv8y146	438	8	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	438	9	processes	process	NNS
cord-024061-gxv8y146	439	1	Novel	novel	JJ
cord-024061-gxv8y146	439	2	reassortant	reassortant	JJ
cord-024061-gxv8y146	439	3	human	human	NN
cord-024061-gxv8y146	439	4	-	-	HYPH
cord-024061-gxv8y146	439	5	Like	like	JJ
cord-024061-gxv8y146	440	1	H3N2	H3N2	NNP
cord-024061-gxv8y146	440	2	and	and	CC
cord-024061-gxv8y146	440	3	H3N1	H3N1	NNP
cord-024061-gxv8y146	440	4	influenza	influenza	NN
cord-024061-gxv8y146	440	5	A	a	DT
cord-024061-gxv8y146	440	6	Viruses	virus	NNS
cord-024061-gxv8y146	440	7	detected	detect	VBN
cord-024061-gxv8y146	440	8	in	in	IN
cord-024061-gxv8y146	440	9	pigs	pig	NNS
cord-024061-gxv8y146	440	10	are	be	VBP
cord-024061-gxv8y146	440	11	virulent	virulent	JJ
cord-024061-gxv8y146	440	12	and	and	CC
cord-024061-gxv8y146	440	13	antigenically	antigenically	RB
cord-024061-gxv8y146	440	14	distinct	distinct	JJ
cord-024061-gxv8y146	440	15	from	from	IN
cord-024061-gxv8y146	440	16	Swine	swine	NN
cord-024061-gxv8y146	440	17	viruses	virus	NNS
cord-024061-gxv8y146	440	18	endemic	endemic	JJ
cord-024061-gxv8y146	440	19	to	to	IN
cord-024061-gxv8y146	440	20	the	the	DT
cord-024061-gxv8y146	440	21	United	United	NNP
cord-024061-gxv8y146	440	22	States	States	NNP
cord-024061-gxv8y146	440	23	Lipman	Lipman	NNP
cord-024061-gxv8y146	440	24	:	:	:
cord-024061-gxv8y146	440	25	the	the	DT
cord-024061-gxv8y146	440	26	influenza	influenza	NN
cord-024061-gxv8y146	440	27	virus	virus	NN
cord-024061-gxv8y146	440	28	resource	resource	NN
cord-024061-gxv8y146	440	29	at	at	IN
cord-024061-gxv8y146	440	30	the	the	DT
cord-024061-gxv8y146	440	31	national	national	JJ
cord-024061-gxv8y146	440	32	center	center	NNP
cord-024061-gxv8y146	440	33	for	for	IN
cord-024061-gxv8y146	440	34	biotechnology	biotechnology	NN
cord-024061-gxv8y146	440	35	information	information	NN
cord-024061-gxv8y146	440	36	Bowman	Bowman	NNP
cord-024061-gxv8y146	440	37	:	:	:
cord-024061-gxv8y146	440	38	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	440	39	dynamics	dynamic	NNS
cord-024061-gxv8y146	440	40	of	of	IN
cord-024061-gxv8y146	440	41	influenza	influenza	NN
cord-024061-gxv8y146	440	42	A	a	DT
cord-024061-gxv8y146	440	43	viruses	virus	NNS
cord-024061-gxv8y146	440	44	in	in	IN
cord-024061-gxv8y146	440	45	US	US	NNP
cord-024061-gxv8y146	440	46	exhibition	exhibition	NN
cord-024061-gxv8y146	440	47	swine	swine	NN
cord-024061-gxv8y146	440	48	Phylogeography	Phylogeography	NNP
cord-024061-gxv8y146	440	49	of	of	IN
cord-024061-gxv8y146	440	50	swine	swine	NN
cord-024061-gxv8y146	440	51	influenza	influenza	NN
cord-024061-gxv8y146	440	52	H3N2	H3N2	NNP
cord-024061-gxv8y146	440	53	in	in	IN
cord-024061-gxv8y146	440	54	the	the	DT
cord-024061-gxv8y146	440	55	United	United	NNP
cord-024061-gxv8y146	440	56	States	States	NNP
cord-024061-gxv8y146	440	57	:	:	:
cord-024061-gxv8y146	440	58	translational	translational	JJ
cord-024061-gxv8y146	440	59	public	public	JJ
cord-024061-gxv8y146	440	60	health	health	NN
cord-024061-gxv8y146	440	61	for	for	IN
cord-024061-gxv8y146	440	62	zoonotic	zoonotic	JJ
cord-024061-gxv8y146	440	63	disease	disease	NN
cord-024061-gxv8y146	440	64	surveillance	surveillance	NN
cord-024061-gxv8y146	440	65	Spatial	spatial	JJ
cord-024061-gxv8y146	440	66	dynamics	dynamic	NNS
cord-024061-gxv8y146	440	67	of	of	IN
cord-024061-gxv8y146	440	68	human	human	JJ
cord-024061-gxv8y146	440	69	-	-	HYPH
cord-024061-gxv8y146	440	70	origin	origin	NN
cord-024061-gxv8y146	440	71	H1	h1	NN
cord-024061-gxv8y146	440	72	influenza	influenza	NN
cord-024061-gxv8y146	441	1	a	a	DT
cord-024061-gxv8y146	441	2	virus	virus	NN
cord-024061-gxv8y146	441	3	in	in	IN
cord-024061-gxv8y146	441	4	North	north	JJ
cord-024061-gxv8y146	441	5	American	american	JJ
cord-024061-gxv8y146	441	6	swine	swine	NN
cord-024061-gxv8y146	441	7	Fast	fast	JJ
cord-024061-gxv8y146	441	8	dating	date	VBG
cord-024061-gxv8y146	441	9	using	use	VBG
cord-024061-gxv8y146	441	10	least	least	JJS
cord-024061-gxv8y146	441	11	-	-	HYPH
cord-024061-gxv8y146	441	12	Squares	square	NNS
cord-024061-gxv8y146	441	13	criteria	criterion	NNS
cord-024061-gxv8y146	441	14	and	and	CC
cord-024061-gxv8y146	441	15	algorithms	algorithm	NNS
cord-024061-gxv8y146	441	16	Prevalence	prevalence	NN
cord-024061-gxv8y146	441	17	of	of	IN
cord-024061-gxv8y146	441	18	influenza	influenza	NN
cord-024061-gxv8y146	442	1	a	a	DT
cord-024061-gxv8y146	442	2	virus	virus	NN
cord-024061-gxv8y146	442	3	in	in	IN
cord-024061-gxv8y146	442	4	exhibition	exhibition	NN
cord-024061-gxv8y146	442	5	swine	swine	NN
cord-024061-gxv8y146	442	6	during	during	IN
cord-024061-gxv8y146	442	7	arrival	arrival	NN
cord-024061-gxv8y146	442	8	at	at	IN
cord-024061-gxv8y146	442	9	agricultural	agricultural	JJ
cord-024061-gxv8y146	442	10	fairs	fair	NNS
cord-024061-gxv8y146	443	1	The	the	DT
cord-024061-gxv8y146	443	2	effects	effect	NNS
cord-024061-gxv8y146	443	3	of	of	IN
cord-024061-gxv8y146	443	4	sampling	sampling	NN
cord-024061-gxv8y146	443	5	strategy	strategy	NN
cord-024061-gxv8y146	443	6	on	on	IN
cord-024061-gxv8y146	443	7	the	the	DT
cord-024061-gxv8y146	443	8	quality	quality	NN
cord-024061-gxv8y146	443	9	of	of	IN
cord-024061-gxv8y146	443	10	reconstruction	reconstruction	NN
cord-024061-gxv8y146	443	11	of	of	IN
cord-024061-gxv8y146	443	12	viral	viral	JJ
cord-024061-gxv8y146	443	13	population	population	NN
cord-024061-gxv8y146	443	14	dynamics	dynamic	NNS
cord-024061-gxv8y146	443	15	using	use	VBG
cord-024061-gxv8y146	443	16	Bayesian	Bayesian	NNP
cord-024061-gxv8y146	443	17	skyline	skyline	NN
cord-024061-gxv8y146	443	18	family	family	NN
cord-024061-gxv8y146	443	19	coalescent	coalescent	NN
cord-024061-gxv8y146	443	20	methods	method	NNS
cord-024061-gxv8y146	443	21	:	:	:
cord-024061-gxv8y146	443	22	a	a	DT
cord-024061-gxv8y146	443	23	simulation	simulation	NN
cord-024061-gxv8y146	443	24	study	study	NN
cord-024061-gxv8y146	443	25	Phylodynamics	phylodynamic	NNS
cord-024061-gxv8y146	443	26	of	of	IN
cord-024061-gxv8y146	443	27	the	the	DT
cord-024061-gxv8y146	443	28	emergence	emergence	NN
cord-024061-gxv8y146	443	29	of	of	IN
cord-024061-gxv8y146	443	30	influenza	influenza	NN
cord-024061-gxv8y146	443	31	viruses	virus	NNS
cord-024061-gxv8y146	443	32	after	after	IN
cord-024061-gxv8y146	443	33	cross	cross	JJ
cord-024061-gxv8y146	443	34	-	-	JJ
cord-024061-gxv8y146	443	35	species	species	JJ
cord-024061-gxv8y146	443	36	transmission	transmission	NN
cord-024061-gxv8y146	444	1	The	the	DT
cord-024061-gxv8y146	444	2	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	444	3	dynamics	dynamic	NNS
cord-024061-gxv8y146	444	4	of	of	IN
cord-024061-gxv8y146	444	5	influenza	influenza	NN
cord-024061-gxv8y146	444	6	a	a	DT
cord-024061-gxv8y146	444	7	virus	virus	NN
cord-024061-gxv8y146	444	8	adaptation	adaptation	NN
cord-024061-gxv8y146	444	9	to	to	IN
cord-024061-gxv8y146	444	10	mammalian	mammalian	JJ
cord-024061-gxv8y146	444	11	hosts	host	NNS
cord-024061-gxv8y146	444	12	Full	full	JJ
cord-024061-gxv8y146	444	13	genome	genome	NN
cord-024061-gxv8y146	444	14	sequencing	sequencing	NN
cord-024061-gxv8y146	444	15	reveals	reveal	VBZ
cord-024061-gxv8y146	444	16	New	New	NNP
cord-024061-gxv8y146	444	17	Southern	southern	JJ
cord-024061-gxv8y146	444	18	African	African	NNP
cord-024061-gxv8y146	444	19	Territories	Territories	NNPS
cord-024061-gxv8y146	444	20	genotypes	genotype	NNS
cord-024061-gxv8y146	444	21	Bringing	bring	VBG
cord-024061-gxv8y146	444	22	us	-PRON-	PRP
cord-024061-gxv8y146	444	23	closer	close	RBR
cord-024061-gxv8y146	444	24	to	to	IN
cord-024061-gxv8y146	444	25	understanding	understand	VBG
cord-024061-gxv8y146	444	26	true	true	JJ
cord-024061-gxv8y146	444	27	variability	variability	NN
cord-024061-gxv8y146	444	28	of	of	IN
cord-024061-gxv8y146	444	29	foot	foot	NN
cord-024061-gxv8y146	444	30	-	-	HYPH
cord-024061-gxv8y146	444	31	and	and	CC
cord-024061-gxv8y146	444	32	-	-	HYPH
cord-024061-gxv8y146	444	33	mouth	mouth	NN
cord-024061-gxv8y146	444	34	disease	disease	NN
cord-024061-gxv8y146	444	35	virus	virus	NN
cord-024061-gxv8y146	444	36	in	in	IN
cord-024061-gxv8y146	444	37	Africa	Africa	NNP
cord-024061-gxv8y146	444	38	Reconstructing	reconstruct	VBG
cord-024061-gxv8y146	444	39	the	the	DT
cord-024061-gxv8y146	444	40	evolutionary	evolutionary	JJ
cord-024061-gxv8y146	444	41	history	history	NN
cord-024061-gxv8y146	444	42	of	of	IN
cord-024061-gxv8y146	444	43	pandemic	pandemic	JJ
cord-024061-gxv8y146	444	44	foot	foot	NN
cord-024061-gxv8y146	444	45	-	-	HYPH
cord-024061-gxv8y146	444	46	and	and	CC
cord-024061-gxv8y146	444	47	-	-	HYPH
cord-024061-gxv8y146	444	48	mouth	mouth	NN
cord-024061-gxv8y146	444	49	disease	disease	NN
cord-024061-gxv8y146	444	50	viruses	virus	NNS
cord-024061-gxv8y146	444	51	:	:	:
cord-024061-gxv8y146	444	52	the	the	DT
cord-024061-gxv8y146	444	53	impact	impact	NN
cord-024061-gxv8y146	444	54	of	of	IN
cord-024061-gxv8y146	444	55	recombination	recombination	NN
cord-024061-gxv8y146	444	56	within	within	IN
cord-024061-gxv8y146	444	57	the	the	DT
cord-024061-gxv8y146	444	58	emerging	emerge	VBG
cord-024061-gxv8y146	445	1	O	o	UH
cord-024061-gxv8y146	445	2	/	/	SYM
cord-024061-gxv8y146	445	3	ME	ME	NNP
cord-024061-gxv8y146	445	4	-	-	HYPH
cord-024061-gxv8y146	445	5	SA	SA	NNP
cord-024061-gxv8y146	445	6	/	/	SYM
cord-024061-gxv8y146	445	7	Ind-2001	Ind-2001	NNP
cord-024061-gxv8y146	445	8	lineage	lineage	NN
cord-024061-gxv8y146	445	9	Evolution	evolution	NN
cord-024061-gxv8y146	445	10	of	of	IN
cord-024061-gxv8y146	445	11	bluetongue	bluetongue	NN
cord-024061-gxv8y146	445	12	virus	virus	NN
cord-024061-gxv8y146	445	13	serotype	serotype	NN
cord-024061-gxv8y146	445	14	1	1	CD
cord-024061-gxv8y146	445	15	in	in	IN
cord-024061-gxv8y146	445	16	northern	northern	JJ
cord-024061-gxv8y146	445	17	Australia	Australia	NNP
cord-024061-gxv8y146	446	1	over	over	IN
cord-024061-gxv8y146	446	2	30	30	CD
cord-024061-gxv8y146	446	3	years	year	NNS
cord-024061-gxv8y146	447	1	Phylodynamics	phylodynamic	NNS
cord-024061-gxv8y146	447	2	of	of	IN
cord-024061-gxv8y146	447	3	H5N1	H5N1	NNP
cord-024061-gxv8y146	447	4	avian	avian	JJ
cord-024061-gxv8y146	447	5	influenza	influenza	NN
cord-024061-gxv8y146	447	6	virus	virus	NN
cord-024061-gxv8y146	447	7	in	in	IN
cord-024061-gxv8y146	447	8	Indonesia	Indonesia	NNP
cord-024061-gxv8y146	447	9	Dynamics	Dynamics	NNPS
cord-024061-gxv8y146	447	10	and	and	CC
cord-024061-gxv8y146	447	11	evolution	evolution	NN
cord-024061-gxv8y146	447	12	of	of	IN
cord-024061-gxv8y146	447	13	highly	highly	RB
cord-024061-gxv8y146	447	14	pathogenic	pathogenic	JJ
cord-024061-gxv8y146	447	15	porcine	porcine	JJ
cord-024061-gxv8y146	447	16	reproductive	reproductive	JJ
cord-024061-gxv8y146	447	17	and	and	CC
cord-024061-gxv8y146	447	18	respiratory	respiratory	JJ
cord-024061-gxv8y146	447	19	syndrome	syndrome	NN
cord-024061-gxv8y146	447	20	virus	virus	NN
cord-024061-gxv8y146	447	21	following	follow	VBG
cord-024061-gxv8y146	447	22	its	-PRON-	PRP$
cord-024061-gxv8y146	447	23	introduction	introduction	NN
cord-024061-gxv8y146	447	24	into	into	IN
cord-024061-gxv8y146	447	25	a	a	DT
cord-024061-gxv8y146	447	26	herd	herd	NN
cord-024061-gxv8y146	447	27	concurrently	concurrently	RB
cord-024061-gxv8y146	447	28	infected	infect	VBN
cord-024061-gxv8y146	447	29	with	with	IN
cord-024061-gxv8y146	447	30	both	both	DT
cord-024061-gxv8y146	447	31	types	type	NNS
cord-024061-gxv8y146	447	32	1	1	CD
cord-024061-gxv8y146	447	33	and	and	CC
cord-024061-gxv8y146	447	34	2	2	CD
cord-024061-gxv8y146	447	35	TreeTime	TreeTime	NNP
cord-024061-gxv8y146	447	36	:	:	:
cord-024061-gxv8y146	447	37	maximum	maximum	JJ
cord-024061-gxv8y146	447	38	-	-	HYPH
cord-024061-gxv8y146	447	39	likelihood	likelihood	JJ
cord-024061-gxv8y146	447	40	phylodynamic	phylodynamic	NN
cord-024061-gxv8y146	447	41	analysis	analysis	NN
cord-024061-gxv8y146	448	1	Scalable	scalable	JJ
cord-024061-gxv8y146	448	2	relaxed	relaxed	JJ
cord-024061-gxv8y146	448	3	clock	clock	NN
cord-024061-gxv8y146	448	4	phylogenetic	phylogenetic	NN
cord-024061-gxv8y146	448	5	dating	date	VBG
cord-024061-gxv8y146	448	6	Phylodynamic	Phylodynamic	NNP
cord-024061-gxv8y146	448	7	applications	application	NNS
cord-024061-gxv8y146	448	8	in	in	IN
cord-024061-gxv8y146	448	9	21(st	21(st	CD
cord-024061-gxv8y146	448	10	)	)	-RRB-
cord-024061-gxv8y146	449	1	century	century	NN
cord-024061-gxv8y146	449	2	global	global	JJ
cord-024061-gxv8y146	449	3	infectious	infectious	JJ
cord-024061-gxv8y146	449	4	disease	disease	NN
cord-024061-gxv8y146	449	5	research	research	NN
cord-024061-gxv8y146	449	6	.	.	.
cord-024061-gxv8y146	450	1	Glob	Glob	NNP
cord-024061-gxv8y146	450	2	Health	Health	NNP
cord-024061-gxv8y146	450	3	Res	Res	NNP
cord-024061-gxv8y146	450	4	Policy	policy	NN
cord-024061-gxv8y146	451	1	The	the	DT
cord-024061-gxv8y146	451	2	study	study	NN
cord-024061-gxv8y146	451	3	was	be	VBD
cord-024061-gxv8y146	451	4	designed	design	VBN
cord-024061-gxv8y146	451	5	by	by	IN
cord-024061-gxv8y146	451	6	MA	MA	NNP
cord-024061-gxv8y146	451	7	and	and	CC
cord-024061-gxv8y146	451	8	MT	MT	NNP
cord-024061-gxv8y146	451	9	.	.	.
cord-024061-gxv8y146	452	1	The	the	DT
cord-024061-gxv8y146	452	2	data	datum	NNS
cord-024061-gxv8y146	452	3	were	be	VBD
cord-024061-gxv8y146	452	4	collected	collect	VBN
cord-024061-gxv8y146	452	5	and	and	CC
cord-024061-gxv8y146	452	6	organized	organize	VBN
cord-024061-gxv8y146	452	7	by	by	IN
cord-024061-gxv8y146	452	8	CL	CL	NNP
cord-024061-gxv8y146	452	9	.	.	.
cord-024061-gxv8y146	453	1	All	all	DT
cord-024061-gxv8y146	453	2	statistical	statistical	JJ
cord-024061-gxv8y146	453	3	analyses	analysis	NNS
cord-024061-gxv8y146	453	4	were	be	VBD
cord-024061-gxv8y146	453	5	conducted	conduct	VBN
cord-024061-gxv8y146	453	6	by	by	IN
cord-024061-gxv8y146	453	7	MA	MA	NNP
cord-024061-gxv8y146	453	8	.	.	.
cord-024061-gxv8y146	454	1	MA	MA	NNP
cord-024061-gxv8y146	454	2	,	,	,
cord-024061-gxv8y146	454	3	CL	CL	NNP
cord-024061-gxv8y146	454	4	,	,	,
cord-024061-gxv8y146	454	5	and	and	CC
cord-024061-gxv8y146	454	6	MT	MT	NNP
cord-024061-gxv8y146	454	7	wrote	write	VBD
cord-024061-gxv8y146	454	8	the	the	DT
cord-024061-gxv8y146	454	9	first	first	JJ
cord-024061-gxv8y146	454	10	draft	draft	NN
cord-024061-gxv8y146	454	11	of	of	IN
cord-024061-gxv8y146	454	12	the	the	DT
cord-024061-gxv8y146	454	13	manuscript	manuscript	NN
cord-024061-gxv8y146	454	14	.	.	.
cord-024061-gxv8y146	455	1	The	the	DT
cord-024061-gxv8y146	455	2	Supplementary	Supplementary	NNP
cord-024061-gxv8y146	455	3	Material	Material	NNP
cord-024061-gxv8y146	455	4	for	for	IN
cord-024061-gxv8y146	455	5	this	this	DT
cord-024061-gxv8y146	455	6	article	article	NN
cord-024061-gxv8y146	455	7	can	can	MD
cord-024061-gxv8y146	455	8	be	be	VB
cord-024061-gxv8y146	455	9	found	find	VBN
cord-024061-gxv8y146	455	10	online	online	RB
cord-024061-gxv8y146	455	11	at	at	IN
cord-024061-gxv8y146	455	12	:	:	:
cord-024061-gxv8y146	455	13	https://www.frontiersin.org/articles/10.3389/fvets	https://www.frontiersin.org/articles/10.3389/fvet	NNS
cord-024061-gxv8y146	455	14	.	.	.
cord-024061-gxv8y146	456	1	2020.00176	2020.00176	CD
cord-024061-gxv8y146	457	1	/full#supplementary	/full#supplementary	JJ
cord-024061-gxv8y146	457	2	-	-	HYPH
cord-024061-gxv8y146	457	3	material	material	NN
cord-024061-gxv8y146	457	4	Conflict	conflict	NN
cord-024061-gxv8y146	457	5	of	of	IN
cord-024061-gxv8y146	457	6	Interest	interest	NN
cord-024061-gxv8y146	457	7	:	:	:
cord-024061-gxv8y146	458	1	The	the	DT
cord-024061-gxv8y146	458	2	authors	author	NNS
cord-024061-gxv8y146	458	3	declare	declare	VBP
cord-024061-gxv8y146	458	4	that	that	IN
cord-024061-gxv8y146	458	5	the	the	DT
cord-024061-gxv8y146	458	6	research	research	NN
cord-024061-gxv8y146	458	7	was	be	VBD
cord-024061-gxv8y146	458	8	conducted	conduct	VBN
cord-024061-gxv8y146	458	9	in	in	IN
cord-024061-gxv8y146	458	10	the	the	DT
cord-024061-gxv8y146	458	11	absence	absence	NN
cord-024061-gxv8y146	458	12	of	of	IN
cord-024061-gxv8y146	458	13	any	any	DT
cord-024061-gxv8y146	458	14	commercial	commercial	JJ
cord-024061-gxv8y146	458	15	or	or	CC
cord-024061-gxv8y146	458	16	financial	financial	JJ
cord-024061-gxv8y146	458	17	relationships	relationship	NNS
cord-024061-gxv8y146	458	18	that	that	WDT
cord-024061-gxv8y146	458	19	could	could	MD
cord-024061-gxv8y146	458	20	be	be	VB
cord-024061-gxv8y146	458	21	construed	construe	VBN
cord-024061-gxv8y146	458	22	as	as	IN
cord-024061-gxv8y146	458	23	a	a	DT
cord-024061-gxv8y146	458	24	potential	potential	JJ
cord-024061-gxv8y146	458	25	conflict	conflict	NN
cord-024061-gxv8y146	458	26	of	of	IN
cord-024061-gxv8y146	458	27	interest	interest	NN
cord-024061-gxv8y146	458	28	.	.	.
cord-024061-gxv8y146	459	1	Copyright	copyright	NN
cord-024061-gxv8y146	459	2	©	©	NN
cord-024061-gxv8y146	459	3	2020	2020	CD
cord-024061-gxv8y146	459	4	Alkhamis	Alkhamis	NNP
cord-024061-gxv8y146	459	5	,	,	,
cord-024061-gxv8y146	459	6	Li	Li	NNP
cord-024061-gxv8y146	459	7	and	and	CC
cord-024061-gxv8y146	459	8	Torremorell	Torremorell	NNP
cord-024061-gxv8y146	459	9	.	.	.
cord-024061-gxv8y146	460	1	This	this	DT
cord-024061-gxv8y146	460	2	is	be	VBZ
cord-024061-gxv8y146	460	3	an	an	DT
cord-024061-gxv8y146	460	4	open	open	JJ
cord-024061-gxv8y146	460	5	-	-	HYPH
cord-024061-gxv8y146	460	6	access	access	NN
cord-024061-gxv8y146	460	7	article	article	NN
cord-024061-gxv8y146	460	8	distributed	distribute	VBN
cord-024061-gxv8y146	460	9	under	under	IN
cord-024061-gxv8y146	460	10	the	the	DT
cord-024061-gxv8y146	460	11	terms	term	NNS
cord-024061-gxv8y146	460	12	of	of	IN
cord-024061-gxv8y146	460	13	the	the	DT
cord-024061-gxv8y146	460	14	Creative	Creative	NNP
cord-024061-gxv8y146	460	15	Commons	Commons	NNP
cord-024061-gxv8y146	460	16	Attribution	Attribution	NNP
cord-024061-gxv8y146	460	17	License	License	NNP
cord-024061-gxv8y146	460	18	(	(	-LRB-
cord-024061-gxv8y146	460	19	CC	CC	NNP
cord-024061-gxv8y146	460	20	BY	BY	NNP
cord-024061-gxv8y146	460	21	)	)	-RRB-
cord-024061-gxv8y146	460	22	.	.	.
cord-024061-gxv8y146	461	1	The	the	DT
cord-024061-gxv8y146	461	2	use	use	NN
cord-024061-gxv8y146	461	3	,	,	,
cord-024061-gxv8y146	461	4	distribution	distribution	NN
cord-024061-gxv8y146	461	5	or	or	CC
cord-024061-gxv8y146	461	6	reproduction	reproduction	NN
cord-024061-gxv8y146	461	7	in	in	IN
cord-024061-gxv8y146	461	8	other	other	JJ
cord-024061-gxv8y146	461	9	forums	forum	NNS
cord-024061-gxv8y146	461	10	is	be	VBZ
cord-024061-gxv8y146	461	11	permitted	permit	VBN
cord-024061-gxv8y146	461	12	,	,	,
cord-024061-gxv8y146	461	13	provided	provide	VBD
cord-024061-gxv8y146	461	14	the	the	DT
cord-024061-gxv8y146	461	15	original	original	JJ
cord-024061-gxv8y146	461	16	author(s	author(s	NNP
cord-024061-gxv8y146	461	17	)	)	-RRB-
cord-024061-gxv8y146	461	18	and	and	CC
cord-024061-gxv8y146	461	19	the	the	DT
cord-024061-gxv8y146	461	20	copyright	copyright	NN
cord-024061-gxv8y146	461	21	owner(s	owner(s	NNP
cord-024061-gxv8y146	461	22	)	)	-RRB-
cord-024061-gxv8y146	461	23	are	be	VBP
cord-024061-gxv8y146	461	24	credited	credit	VBN
cord-024061-gxv8y146	461	25	and	and	CC
cord-024061-gxv8y146	461	26	that	that	IN
cord-024061-gxv8y146	461	27	the	the	DT
cord-024061-gxv8y146	461	28	original	original	JJ
cord-024061-gxv8y146	461	29	publication	publication	NN
cord-024061-gxv8y146	461	30	in	in	IN
cord-024061-gxv8y146	461	31	this	this	DT
cord-024061-gxv8y146	461	32	journal	journal	NN
cord-024061-gxv8y146	461	33	is	be	VBZ
cord-024061-gxv8y146	461	34	cited	cite	VBN
cord-024061-gxv8y146	461	35	,	,	,
cord-024061-gxv8y146	461	36	in	in	IN
cord-024061-gxv8y146	461	37	accordance	accordance	NN
cord-024061-gxv8y146	461	38	with	with	IN
cord-024061-gxv8y146	461	39	accepted	accepted	JJ
cord-024061-gxv8y146	461	40	academic	academic	JJ
cord-024061-gxv8y146	461	41	practice	practice	NN
cord-024061-gxv8y146	461	42	.	.	.
cord-024061-gxv8y146	462	1	No	no	DT
cord-024061-gxv8y146	462	2	use	use	NN
cord-024061-gxv8y146	462	3	,	,	,
cord-024061-gxv8y146	462	4	distribution	distribution	NN
cord-024061-gxv8y146	462	5	or	or	CC
cord-024061-gxv8y146	462	6	reproduction	reproduction	NN
cord-024061-gxv8y146	462	7	is	be	VBZ
cord-024061-gxv8y146	462	8	permitted	permit	VBN
cord-024061-gxv8y146	462	9	which	which	WDT
cord-024061-gxv8y146	462	10	does	do	VBZ
cord-024061-gxv8y146	462	11	not	not	RB
cord-024061-gxv8y146	462	12	comply	comply	VB
cord-024061-gxv8y146	462	13	with	with	IN
cord-024061-gxv8y146	462	14	these	these	DT
cord-024061-gxv8y146	462	15	terms	term	NNS
cord-024061-gxv8y146	462	16	.	.	.