id author title date pages extension mime words sentences flesch summary cache txt cord-285676-4kgy20o9 de Vries, Antoine A.F. The Genome Organization of the Nidovirales: Similarities and Differences between Arteri-, Toro-, and Coronaviruses 1997-02-28 .txt text/plain 7980 437 53 The overlapping ORFs 1a and b found at the 58 end of the nidoviral genome are frequently referred to as the ''polymerase gene.'' However, there is little doubt that the processing of the encoded polyproteins yields proteins required for RNA synthesis as well as a number of products involved in other aspects of virus replication. The sequence conservation between the more closely related corona-and toroviruses is clustered in six domains, four of which are also found in the arterivirus POL1b: the ''classical'' RNA-dependent RNA polymerase (RdRp) and helicase (H) domains, which are also present in the polymerases of most other viruses, a zinc finger motif (zf), and a short region of 80-100 residues, which has not yet been identified in other viral polymerases and was called the ''coronavirus-like'' (CVL) domain (3) (motif 2 in Fig. 1b) . ./cache/cord-285676-4kgy20o9.txt ./txt/cord-285676-4kgy20o9.txt