id author title date pages extension mime words sentences flesch summary cache txt cord-274247-5qiwui6u Torrecilhas, A C T Interference of natural mouse hepatitis virus infection with cytokine production and susceptibility to Trypanosoma cruzi 1999-03-01 .txt text/plain 4017 185 49 We have investigated the effects of a natural acute outbreak of MHV in our otherwise specific-pathogen-free (SPF) inbred mouse colonies, and of enzootic chronic MHV infection on cytokine production and resistance to the intracellular pathogen Trypanosoma cruzi. IL-10 that were serologically MHV+ or MHV− production, on day 11 after infection, in BALB/c (but not in C57BL/6) mice was CD4-activation dependent as treatment Our preliminary observation, suggestive of an infection with GK1.5 mAb suppressed most of its synthesis outbreak in the mouse colonies, was increased susceptibility (63 units/ml in untreated versus 6 units/ml in GK1.5 treated to T. cruzi determined by the situation of acute MHV+ C57BL/6 and BALB/c mice cells to Con A stimulation simultaneous infection with blood parasites derived from was not significantly higher than in spleen cell cultures from acutely infected MHV+ donors as described above, no statis-MHV− animals (Fig. 2) . ./cache/cord-274247-5qiwui6u.txt ./txt/cord-274247-5qiwui6u.txt