id author title date pages extension mime words sentences flesch summary cache txt cord-263658-dlmzcl9g MCINTOSH, KENNETH SEROEPIDEMIOLOGIC STUDIES OF CORONAVIRUS INFECTION IN ADULTS AND CHILDREN(1) 1970-06-17 .txt text/plain 2572 139 52 authors: MCINTOSH, KENNETH; KAPIKIAN, ALBERT Z.; TURNER, HORACE C.; HARTLEY, JANET W.; PARROTT, ROBERT H.; CHANOCK, ROBERT M. Table 1 shows the proportion of infants and children with and without LRTD showing fourfold or greater antibody responses to the three related coronavirus antigens OC38, OC43, and MHV, strain A-59. It is evident from the studies of hospitalized children that infection with coronaviruses was not significantly associated in this survey with pediatric lower respiratory tract disease. It is of interest that in the seroepidemiologic studies of Hartley and others, where several strains of MHV were tested with sera from military recruits, no epidemiologic association of MHV or MHV-like virus infection with respiratory tract disease was made (11) . Antigenic studies of human coronaviruses have shown that those members of the group which were originally recovered in tissue culture are all closely related to the prototype virus strain 229E (2, 5) . ./cache/cord-263658-dlmzcl9g.txt ./txt/cord-263658-dlmzcl9g.txt