id author title date pages extension mime words sentences flesch summary cache txt cord-356192-8b96rgqa Xie, Qian Two deletion variants of Middle East respiratory syndrome coronavirus found in a patient with characteristic symptoms 2017-04-18 .txt text/plain 2413 131 52 title: Two deletion variants of Middle East respiratory syndrome coronavirus found in a patient with characteristic symptoms Significant sequence variation of Middle East respiratory syndrome coronavirus (MERS CoV) has never been detected since it was first reported in 2012. To predict the function of the E protein of MERS CoV, we aligned the E and ORF5-E protein sequences of MERS CoV with those of two other coronaviruses, SARS-CoV and China Rattus coronavirus HKU24, using MEGA software (version 6.0) [11] . The truncated E protein with a deletion of aa 1-30 lacks the N-terminus and a major part of the hydrophobic transmembrane domain in MERS CoV variant 1, which might directly impair virus packaging and replication [24] . Genomic sequencing and analysis of the first imported Middle East Respiratory Syndrome Coronavirus (MERS CoV) in China Middle East respiratory syndrome coronavirus (MERS-CoV) entry inhibitors targeting spike protein ./cache/cord-356192-8b96rgqa.txt ./txt/cord-356192-8b96rgqa.txt