id author title date pages extension mime words sentences flesch summary cache txt cord-343184-kptkmgdm Crameri, Gary Experimental Infection and Response to Rechallenge of Alpacas with Middle East Respiratory Syndrome Coronavirus 2016-06-17 .txt text/plain 1606 77 47 title: Experimental Infection and Response to Rechallenge of Alpacas with Middle East Respiratory Syndrome Coronavirus We conducted a challenge/rechallenge trial in which 3 alpacas were infected with Middle East respiratory syndrome coronavirus. However, the alpaca, a close relative within the Camelidae family, may provide a temperamentally suitable and valuable animal model for MERS-CoV infection, particularly for developing and testing vaccine candidates for camels. We found no previous MERS-CoV challenge trial reported in alpacas, so we chose a preliminary dose and rechallenge time on the basis of our experience with other virus infection trials for other emerging infectious diseases (8) . Our challenge/rechallenge trial was planned as a first stage in the assessment of the alpaca as a potential surrogate for camels for MERS-CoV vaccine testing. Middle East respiratory syndrome coronavirus neutralising serum antibodies in dromedary camels: a comparative serological study Infection, replication, and transmission of Middle East respiratory syndrome coronavirus in alpacas ./cache/cord-343184-kptkmgdm.txt ./txt/cord-343184-kptkmgdm.txt