id author title date pages extension mime words sentences flesch summary cache txt cord-301103-idu4j78a Sohrab, Sayed S. Genetic diversity of MERS-CoV spike protein gene in Saudi Arabia 2019-12-09 .txt text/plain 4256 221 53 The nucleotide and amino acid sequences of MERS-CoV Spike protein gene were used to analyze the recombination, genetic diversity and phylogenetic relationship with selected sequences from Saudi Arabia. Recently, in another study, total 530 nucleotides deletion was observed in Spike gene from serum samples collected from Taif, Saudi Arabia and a novel genetic variant of MERS-CoV was designated as a quasispecies [29] . Multiple substitutions of amino acids were observed in RBD, part of Spike gene from a bat sample collected from Uganda and the recombination in the S1 subunit of the Spike gene was observed and it was expected that this variation likely to play an important role in the emergence of MERS-CoV causing disease in human [30] . The detection of MERS-CoV in human and camel determining the genetic diversity among Spike gene will further help researchers as well as health authority to design and develop an effective disease management and control strategies in the Kingdom of Saudi Arabia. ./cache/cord-301103-idu4j78a.txt ./txt/cord-301103-idu4j78a.txt