id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-288167-976qxja2	Park, Wan Beom	Replicative virus shedding in the respiratory tract of patients with Middle East respiratory syndrome coronavirus infection	2018-05-09		.txt	text/plain	1373	87	52	title: Replicative virus shedding in the respiratory tract of patients with Middle East respiratory syndrome coronavirus infection BACKGROUND: Information on the duration of replicative Middle East respiratory syndrome coronavirus (MERS-CoV) shedding is important for infection control. This study examined the duration for detecting MERS-CoV sub-genomic mRNA compared with genomic RNA in diverse respiratory specimens. In the present study, replicative MERS-CoV was detected in sputum or transtracheal aspirate for up to 4 weeks after symptom development in MERS-CoV-infected patients with severe pneumonia. In conclusion, replicative MERS-CoV was detected in lower respiratory tract specimens for up to 4 weeks after symptom development, which was well correlated with the detection of genomic RNA. In upper respiratory tract specimens, the detection of sub-genomic mRNA and genomic RNA did not correlate. Middle East respiratory syndrome coronavirus (MERS-CoV) genomic RNA (upE) titers in sputum and transtracheal aspirates with vs.	./cache/cord-288167-976qxja2.txt	./txt/cord-288167-976qxja2.txt