id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-278238-w1l8h8g8	Okba, Nisreen MA	Middle East respiratory syndrome coronavirus vaccines: current status and novel approaches	2017-04-13		.txt	text/plain	5086	226	39	Nisreen MA Okba, V Stalin Raj and Bart L Haagmans Middle East respiratory syndrome coronavirus (MERS-CoV) is a cause of severe respiratory infection in humans, specifically the elderly and people with comorbidities. The other candidate MVA-S, a viral-vector-based vaccine, induced systemic neutralizing antibodies and mucosal immunity which conferred protection against MERS-CoV challenge and reduced virus shedding in vaccinated camels [52 ] Therefore, this vaccine candidate may provide a means to prevent zoonotic transmission of the virus to the human population. Prophylaxis with a Middle East respiratory syndrome coronavirus (MERS-CoV)-specific human monoclonal antibody protects rabbits from MERS-CoV infection T cell responses are required for protection from clinical disease and for virus clearance in severe acute respiratory syndrome coronavirus-infected mice The recombinant Nterminal domain of spike proteins is a potential vaccine against Middle East respiratory syndrome coronavirus (MERS-CoV) infection	./cache/cord-278238-w1l8h8g8.txt	./txt/cord-278238-w1l8h8g8.txt