id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-002070-8y24j34j	Adney, Danielle R.	Infection, Replication, and Transmission of Middle East Respiratory Syndrome Coronavirus in Alpacas	2016-06-17		.txt	text/plain	3090	164	46	Numerous investigators have reported the presence of MERS-CoV RNA or infectious virus in nasal swab specimens of dromedary camels in Saudi Arabia (3, 4, (8) (9) (10) , Qatar (5, (11) (12) (13) , Oman (14) , the United Arab Emirates (15), Nigeria (16) , and Egypt (17) . We have previously demonstrated that dromedary camels can be experimentally infected with MERS-CoV and found that mild upper respiratory tract disease associated with shedding copious amounts of virus by nasal secretions develops during the first week after infection (21) . We report characterization of an alpaca model of MERS-CoV infection in which we evaluated virus shedding and pathology, transmission by contact, and protective immunity 10 weeks after initial infection. Infectious virus was detected in nasal swab specimens from 2 of 3 alpacas co-housed with experimentally infected animals, and each of the 3 co-housed animals had neutralizing antibodies against MERS-CoV, which indicated virus transmission.	./cache/cord-002070-8y24j34j.txt	./txt/cord-002070-8y24j34j.txt