id	sid	tid	token	lemma	pos
cord-287093-9mertwj7	1	1	key	key	JJ
cord-287093-9mertwj7	1	2	:	:	:
cord-287093-9mertwj7	1	3	cord-287093	cord-287093	NNP
cord-287093-9mertwj7	1	4	-	-	HYPH
cord-287093-9mertwj7	1	5	9mertwj7	9mertwj7	CD
cord-287093-9mertwj7	2	1	authors	author	NNS
cord-287093-9mertwj7	2	2	:	:	:
cord-287093-9mertwj7	2	3	Netherton	Netherton	NNP
cord-287093-9mertwj7	2	4	,	,	,
cord-287093-9mertwj7	2	5	Christopher	Christopher	NNP
cord-287093-9mertwj7	2	6	L	L	NNP
cord-287093-9mertwj7	2	7	;	;	:
cord-287093-9mertwj7	2	8	Wileman	Wileman	NNP
cord-287093-9mertwj7	2	9	,	,	,
cord-287093-9mertwj7	2	10	Tom	Tom	NNP
cord-287093-9mertwj7	2	11	title	title	NN
cord-287093-9mertwj7	2	12	:	:	:
cord-287093-9mertwj7	3	1	Virus	virus	NN
cord-287093-9mertwj7	3	2	factories	factory	NNS
cord-287093-9mertwj7	3	3	,	,	,
cord-287093-9mertwj7	3	4	double	double	JJ
cord-287093-9mertwj7	3	5	membrane	membrane	NN
cord-287093-9mertwj7	3	6	vesicles	vesicle	NNS
cord-287093-9mertwj7	3	7	and	and	CC
cord-287093-9mertwj7	3	8	viroplasm	viroplasm	NN
cord-287093-9mertwj7	3	9	generated	generate	VBN
cord-287093-9mertwj7	3	10	in	in	IN
cord-287093-9mertwj7	3	11	animal	animal	NN
cord-287093-9mertwj7	3	12	cells	cell	NNS
cord-287093-9mertwj7	3	13	date	date	NN
cord-287093-9mertwj7	3	14	:	:	:
cord-287093-9mertwj7	3	15	2011	2011	CD
cord-287093-9mertwj7	3	16	-	-	SYM
cord-287093-9mertwj7	3	17	10	10	CD
cord-287093-9mertwj7	3	18	-	-	SYM
cord-287093-9mertwj7	3	19	12	12	CD
cord-287093-9mertwj7	3	20	journal	journal	NN
cord-287093-9mertwj7	3	21	:	:	:
cord-287093-9mertwj7	4	1	Curr	Curr	NNP
cord-287093-9mertwj7	4	2	Opin	Opin	NNP
cord-287093-9mertwj7	5	1	Virol	Virol	NNP
cord-287093-9mertwj7	5	2	DOI	doi	NN
cord-287093-9mertwj7	5	3	:	:	:
cord-287093-9mertwj7	6	1	10.1016	10.1016	CD
cord-287093-9mertwj7	6	2	/	/	SYM
cord-287093-9mertwj7	6	3	j.coviro.2011.09.008	j.coviro.2011.09.008	JJ
cord-287093-9mertwj7	6	4	sha	sha	NNP
cord-287093-9mertwj7	6	5	:	:	:
cord-287093-9mertwj7	7	1	29acc30bc747c7a6d6d4b9c838b26a9e9dc38850	29acc30bc747c7a6d6d4b9c838b26a9e9dc38850	CD
cord-287093-9mertwj7	7	2	doc_id	doc_id	CD
cord-287093-9mertwj7	7	3	:	:	:
cord-287093-9mertwj7	8	1	287093	287093	CD
cord-287093-9mertwj7	8	2	cord_uid	cord_uid	NN
cord-287093-9mertwj7	8	3	:	:	:
cord-287093-9mertwj7	9	1	9mertwj7	9mertwj7	CD
cord-287093-9mertwj7	10	1	Many	many	JJ
cord-287093-9mertwj7	10	2	viruses	virus	NNS
cord-287093-9mertwj7	10	3	reorganise	reorganise	VBP
cord-287093-9mertwj7	10	4	cellular	cellular	JJ
cord-287093-9mertwj7	10	5	membrane	membrane	NN
cord-287093-9mertwj7	10	6	compartments	compartment	NNS
cord-287093-9mertwj7	10	7	and	and	CC
cord-287093-9mertwj7	10	8	the	the	DT
cord-287093-9mertwj7	10	9	cytoskeleton	cytoskeleton	NN
cord-287093-9mertwj7	10	10	to	to	TO
cord-287093-9mertwj7	10	11	generate	generate	VB
cord-287093-9mertwj7	10	12	subcellular	subcellular	JJ
cord-287093-9mertwj7	10	13	microenvironments	microenvironment	NNS
cord-287093-9mertwj7	10	14	called	call	VBN
cord-287093-9mertwj7	10	15	virus	virus	NN
cord-287093-9mertwj7	10	16	factories	factory	NNS
cord-287093-9mertwj7	10	17	or	or	CC
cord-287093-9mertwj7	10	18	‘	'	``
cord-287093-9mertwj7	10	19	viroplasm	viroplasm	NNP
cord-287093-9mertwj7	10	20	’	'	''
cord-287093-9mertwj7	10	21	.	.	.
cord-287093-9mertwj7	11	1	These	these	DT
cord-287093-9mertwj7	11	2	create	create	VBP
cord-287093-9mertwj7	11	3	a	a	DT
cord-287093-9mertwj7	11	4	platform	platform	NN
cord-287093-9mertwj7	11	5	to	to	TO
cord-287093-9mertwj7	11	6	concentrate	concentrate	VB
cord-287093-9mertwj7	11	7	replicase	replicase	NN
cord-287093-9mertwj7	11	8	proteins	protein	NNS
cord-287093-9mertwj7	11	9	,	,	,
cord-287093-9mertwj7	11	10	virus	virus	NN
cord-287093-9mertwj7	11	11	genomes	genome	NNS
cord-287093-9mertwj7	11	12	and	and	CC
cord-287093-9mertwj7	11	13	host	host	NN
cord-287093-9mertwj7	11	14	proteins	protein	NNS
cord-287093-9mertwj7	11	15	required	require	VBN
cord-287093-9mertwj7	11	16	for	for	IN
cord-287093-9mertwj7	11	17	replication	replication	NN
cord-287093-9mertwj7	11	18	and	and	CC
cord-287093-9mertwj7	11	19	also	also	RB
cord-287093-9mertwj7	11	20	protect	protect	VB
cord-287093-9mertwj7	11	21	against	against	IN
cord-287093-9mertwj7	11	22	antiviral	antiviral	JJ
cord-287093-9mertwj7	11	23	defences	defence	NNS
cord-287093-9mertwj7	11	24	.	.	.
cord-287093-9mertwj7	12	1	There	there	EX
cord-287093-9mertwj7	12	2	is	be	VBZ
cord-287093-9mertwj7	12	3	growing	grow	VBG
cord-287093-9mertwj7	12	4	interest	interest	NN
cord-287093-9mertwj7	12	5	in	in	IN
cord-287093-9mertwj7	12	6	understanding	understand	VBG
cord-287093-9mertwj7	12	7	how	how	WRB
cord-287093-9mertwj7	12	8	viruses	virus	NNS
cord-287093-9mertwj7	12	9	induce	induce	VBP
cord-287093-9mertwj7	12	10	such	such	JJ
cord-287093-9mertwj7	12	11	large	large	JJ
cord-287093-9mertwj7	12	12	changes	change	NNS
cord-287093-9mertwj7	12	13	in	in	IN
cord-287093-9mertwj7	12	14	cellular	cellular	JJ
cord-287093-9mertwj7	12	15	organisation	organisation	NN
cord-287093-9mertwj7	12	16	,	,	,
cord-287093-9mertwj7	12	17	and	and	CC
cord-287093-9mertwj7	12	18	recent	recent	JJ
cord-287093-9mertwj7	12	19	studies	study	NNS
cord-287093-9mertwj7	12	20	are	be	VBP
cord-287093-9mertwj7	12	21	beginning	begin	VBG
cord-287093-9mertwj7	12	22	to	to	TO
cord-287093-9mertwj7	12	23	reveal	reveal	VB
cord-287093-9mertwj7	12	24	the	the	DT
cord-287093-9mertwj7	12	25	relationship	relationship	NN
cord-287093-9mertwj7	12	26	between	between	IN
cord-287093-9mertwj7	12	27	virus	virus	NN
cord-287093-9mertwj7	12	28	factories	factory	NNS
cord-287093-9mertwj7	12	29	and	and	CC
cord-287093-9mertwj7	12	30	viroplasm	viroplasm	NN
cord-287093-9mertwj7	12	31	and	and	CC
cord-287093-9mertwj7	12	32	the	the	DT
cord-287093-9mertwj7	12	33	cellular	cellular	JJ
cord-287093-9mertwj7	12	34	structures	structure	NNS
cord-287093-9mertwj7	12	35	that	that	WDT
cord-287093-9mertwj7	12	36	house	house	VBP
cord-287093-9mertwj7	12	37	them	-PRON-	PRP
cord-287093-9mertwj7	12	38	.	.	.
cord-287093-9mertwj7	13	1	In	in	IN
cord-287093-9mertwj7	13	2	this	this	DT
cord-287093-9mertwj7	13	3	review	review	NN
cord-287093-9mertwj7	13	4	,	,	,
cord-287093-9mertwj7	13	5	we	-PRON-	PRP
cord-287093-9mertwj7	13	6	discuss	discuss	VBP
cord-287093-9mertwj7	13	7	how	how	WRB
cord-287093-9mertwj7	13	8	three	three	CD
cord-287093-9mertwj7	13	9	supergroups	supergroup	NNS
cord-287093-9mertwj7	13	10	of	of	IN
cord-287093-9mertwj7	13	11	(	(	-LRB-
cord-287093-9mertwj7	13	12	+	+	CC
cord-287093-9mertwj7	13	13	)	)	-RRB-
cord-287093-9mertwj7	13	14	RNA	rna	NN
cord-287093-9mertwj7	13	15	viruses	virus	NNS
cord-287093-9mertwj7	13	16	generate	generate	VBP
cord-287093-9mertwj7	13	17	replication	replication	NN
cord-287093-9mertwj7	13	18	sites	site	NNS
cord-287093-9mertwj7	13	19	from	from	IN
cord-287093-9mertwj7	13	20	membrane	membrane	NN
cord-287093-9mertwj7	13	21	-	-	HYPH
cord-287093-9mertwj7	13	22	bound	bind	VBN
cord-287093-9mertwj7	13	23	organelles	organelle	NNS
cord-287093-9mertwj7	13	24	and	and	CC
cord-287093-9mertwj7	13	25	highlight	highlight	VBP
cord-287093-9mertwj7	13	26	research	research	NN
cord-287093-9mertwj7	13	27	on	on	IN
cord-287093-9mertwj7	13	28	perinuclear	perinuclear	NNP
cord-287093-9mertwj7	13	29	factories	factory	NNS
cord-287093-9mertwj7	13	30	induced	induce	VBN
cord-287093-9mertwj7	13	31	by	by	IN
cord-287093-9mertwj7	13	32	the	the	DT
cord-287093-9mertwj7	13	33	nucleocytoplasmic	nucleocytoplasmic	JJ
cord-287093-9mertwj7	13	34	large	large	JJ
cord-287093-9mertwj7	13	35	DNA	dna	NN
cord-287093-9mertwj7	13	36	viruses	virus	NNS
cord-287093-9mertwj7	13	37	.	.	.
cord-287093-9mertwj7	14	1	Many	many	JJ
cord-287093-9mertwj7	14	2	viruses	virus	NNS
cord-287093-9mertwj7	14	3	replicate	replicate	VBP
cord-287093-9mertwj7	14	4	within	within	IN
cord-287093-9mertwj7	14	5	subcellular	subcellular	JJ
cord-287093-9mertwj7	14	6	microenvironments	microenvironment	NNS
cord-287093-9mertwj7	14	7	or	or	CC
cord-287093-9mertwj7	14	8	'	'	``
cord-287093-9mertwj7	14	9	mini	mini	JJ
cord-287093-9mertwj7	14	10	-	-	JJ
cord-287093-9mertwj7	14	11	organelles	organelle	NNS
cord-287093-9mertwj7	14	12	'	'	''
cord-287093-9mertwj7	14	13	called	call	VBN
cord-287093-9mertwj7	14	14	virus	virus	NN
cord-287093-9mertwj7	14	15	factories	factory	NNS
cord-287093-9mertwj7	14	16	or	or	CC
cord-287093-9mertwj7	14	17	'	'	``
cord-287093-9mertwj7	14	18	viroplasm	viroplasm	NN
cord-287093-9mertwj7	14	19	'	'	''
cord-287093-9mertwj7	14	20	.	.	.
cord-287093-9mertwj7	15	1	Formation	formation	NN
cord-287093-9mertwj7	15	2	of	of	IN
cord-287093-9mertwj7	15	3	these	these	DT
cord-287093-9mertwj7	15	4	structures	structure	NNS
cord-287093-9mertwj7	15	5	involves	involve	VBZ
cord-287093-9mertwj7	15	6	rearrangement	rearrangement	NN
cord-287093-9mertwj7	15	7	of	of	IN
cord-287093-9mertwj7	15	8	host	host	NN
cord-287093-9mertwj7	15	9	cell	cell	NN
cord-287093-9mertwj7	15	10	membranes	membrane	NNS
cord-287093-9mertwj7	15	11	and	and	CC
cord-287093-9mertwj7	15	12	cytoskeleton	cytoskeleton	NN
cord-287093-9mertwj7	15	13	and	and	CC
cord-287093-9mertwj7	15	14	induces	induce	VBZ
cord-287093-9mertwj7	15	15	a	a	DT
cord-287093-9mertwj7	15	16	'	'	``
cord-287093-9mertwj7	15	17	cytopathic	cytopathic	JJ
cord-287093-9mertwj7	15	18	effect	effect	NN
cord-287093-9mertwj7	15	19	'	'	''
cord-287093-9mertwj7	15	20	indicative	indicative	JJ
cord-287093-9mertwj7	15	21	of	of	IN
cord-287093-9mertwj7	15	22	virus	virus	NN
cord-287093-9mertwj7	15	23	infection	infection	NN
cord-287093-9mertwj7	15	24	.	.	.
cord-287093-9mertwj7	16	1	It	-PRON-	PRP
cord-287093-9mertwj7	16	2	is	be	VBZ
cord-287093-9mertwj7	16	3	generally	generally	RB
cord-287093-9mertwj7	16	4	believed	believe	VBN
cord-287093-9mertwj7	16	5	that	that	IN
cord-287093-9mertwj7	16	6	factories	factory	NNS
cord-287093-9mertwj7	16	7	and	and	CC
cord-287093-9mertwj7	16	8	viroplasm	viroplasm	NN
cord-287093-9mertwj7	16	9	create	create	VBP
cord-287093-9mertwj7	16	10	a	a	DT
cord-287093-9mertwj7	16	11	platform	platform	NN
cord-287093-9mertwj7	16	12	to	to	TO
cord-287093-9mertwj7	16	13	concentrate	concentrate	VB
cord-287093-9mertwj7	16	14	replicase	replicase	NN
cord-287093-9mertwj7	16	15	proteins	protein	NNS
cord-287093-9mertwj7	16	16	,	,	,
cord-287093-9mertwj7	16	17	virus	virus	NN
cord-287093-9mertwj7	16	18	genomes	genome	NNS
cord-287093-9mertwj7	16	19	and	and	CC
cord-287093-9mertwj7	16	20	host	host	NN
cord-287093-9mertwj7	16	21	proteins	protein	NNS
cord-287093-9mertwj7	16	22	required	require	VBN
cord-287093-9mertwj7	16	23	for	for	IN
cord-287093-9mertwj7	16	24	replication	replication	NN
cord-287093-9mertwj7	16	25	,	,	,
cord-287093-9mertwj7	16	26	and	and	CC
cord-287093-9mertwj7	16	27	at	at	IN
cord-287093-9mertwj7	16	28	the	the	DT
cord-287093-9mertwj7	16	29	same	same	JJ
cord-287093-9mertwj7	16	30	time	time	NN
cord-287093-9mertwj7	16	31	physically	physically	RB
cord-287093-9mertwj7	16	32	separate	separate	JJ
cord-287093-9mertwj7	16	33	replication	replication	NN
cord-287093-9mertwj7	16	34	sites	site	NNS
cord-287093-9mertwj7	16	35	from	from	IN
cord-287093-9mertwj7	16	36	a	a	DT
cord-287093-9mertwj7	16	37	myriad	myriad	NN
cord-287093-9mertwj7	16	38	of	of	IN
cord-287093-9mertwj7	16	39	cellular	cellular	JJ
cord-287093-9mertwj7	16	40	antiviral	antiviral	JJ
cord-287093-9mertwj7	16	41	defences	defence	NNS
cord-287093-9mertwj7	16	42	.	.	.
cord-287093-9mertwj7	17	1	The	the	DT
cord-287093-9mertwj7	17	2	subversion	subversion	NN
cord-287093-9mertwj7	17	3	of	of	IN
cord-287093-9mertwj7	17	4	membrane	membrane	NN
cord-287093-9mertwj7	17	5	trafficking	traffic	VBG
cord-287093-9mertwj7	17	6	pathways	pathway	NNS
cord-287093-9mertwj7	17	7	during	during	IN
cord-287093-9mertwj7	17	8	the	the	DT
cord-287093-9mertwj7	17	9	formation	formation	NN
cord-287093-9mertwj7	17	10	of	of	IN
cord-287093-9mertwj7	17	11	replication	replication	NN
cord-287093-9mertwj7	17	12	sites	site	NNS
cord-287093-9mertwj7	17	13	may	may	MD
cord-287093-9mertwj7	17	14	add	add	VB
cord-287093-9mertwj7	17	15	further	further	JJ
cord-287093-9mertwj7	17	16	benefit	benefit	NN
cord-287093-9mertwj7	17	17	by	by	IN
cord-287093-9mertwj7	17	18	slowing	slow	VBG
cord-287093-9mertwj7	17	19	the	the	DT
cord-287093-9mertwj7	17	20	transport	transport	NN
cord-287093-9mertwj7	17	21	of	of	IN
cord-287093-9mertwj7	17	22	immunomodulatory	immunomodulatory	JJ
cord-287093-9mertwj7	17	23	proteins	protein	NNS
cord-287093-9mertwj7	17	24	to	to	IN
cord-287093-9mertwj7	17	25	the	the	DT
cord-287093-9mertwj7	17	26	surface	surface	NN
cord-287093-9mertwj7	17	27	of	of	IN
cord-287093-9mertwj7	17	28	infected	infected	JJ
cord-287093-9mertwj7	17	29	cells	cell	NNS
cord-287093-9mertwj7	17	30	to	to	TO
cord-287093-9mertwj7	17	31	protect	protect	VB
cord-287093-9mertwj7	17	32	against	against	IN
cord-287093-9mertwj7	17	33	immune	immune	JJ
cord-287093-9mertwj7	17	34	responses	response	NNS
cord-287093-9mertwj7	17	35	,	,	,
cord-287093-9mertwj7	17	36	while	while	IN
cord-287093-9mertwj7	17	37	disruption	disruption	NN
cord-287093-9mertwj7	17	38	of	of	IN
cord-287093-9mertwj7	17	39	the	the	DT
cord-287093-9mertwj7	17	40	cytoskeleton	cytoskeleton	NN
cord-287093-9mertwj7	17	41	may	may	MD
cord-287093-9mertwj7	17	42	enhance	enhance	VB
cord-287093-9mertwj7	17	43	release	release	NN
cord-287093-9mertwj7	17	44	of	of	IN
cord-287093-9mertwj7	17	45	viruses	virus	NNS
cord-287093-9mertwj7	17	46	from	from	IN
cord-287093-9mertwj7	17	47	cells	cell	NNS
cord-287093-9mertwj7	17	48	.	.	.
cord-287093-9mertwj7	18	1	There	there	EX
cord-287093-9mertwj7	18	2	is	be	VBZ
cord-287093-9mertwj7	18	3	growing	grow	VBG
cord-287093-9mertwj7	18	4	interest	interest	NN
cord-287093-9mertwj7	18	5	in	in	IN
cord-287093-9mertwj7	18	6	understanding	understand	VBG
cord-287093-9mertwj7	18	7	how	how	WRB
cord-287093-9mertwj7	18	8	viruses	virus	NNS
cord-287093-9mertwj7	18	9	induce	induce	VBP
cord-287093-9mertwj7	18	10	such	such	JJ
cord-287093-9mertwj7	18	11	large	large	JJ
cord-287093-9mertwj7	18	12	changes	change	NNS
cord-287093-9mertwj7	18	13	in	in	IN
cord-287093-9mertwj7	18	14	cellular	cellular	JJ
cord-287093-9mertwj7	18	15	organisation	organisation	NN
cord-287093-9mertwj7	18	16	,	,	,
cord-287093-9mertwj7	18	17	and	and	CC
cord-287093-9mertwj7	18	18	recent	recent	JJ
cord-287093-9mertwj7	18	19	advances	advance	NNS
cord-287093-9mertwj7	18	20	in	in	IN
cord-287093-9mertwj7	18	21	electron	electron	NN
cord-287093-9mertwj7	18	22	microscopy	microscopy	NN
cord-287093-9mertwj7	18	23	coupled	couple	VBN
cord-287093-9mertwj7	18	24	with	with	IN
cord-287093-9mertwj7	18	25	tomography	tomography	NN
cord-287093-9mertwj7	18	26	and	and	CC
cord-287093-9mertwj7	18	27	live	live	JJ
cord-287093-9mertwj7	18	28	cell	cell	NN
cord-287093-9mertwj7	18	29	imaging	imaging	NN
cord-287093-9mertwj7	18	30	are	be	VBP
cord-287093-9mertwj7	18	31	beginning	begin	VBG
cord-287093-9mertwj7	18	32	to	to	TO
cord-287093-9mertwj7	18	33	reveal	reveal	VB
cord-287093-9mertwj7	18	34	the	the	DT
cord-287093-9mertwj7	18	35	relationship	relationship	NN
cord-287093-9mertwj7	18	36	between	between	IN
cord-287093-9mertwj7	18	37	virus	virus	NN
cord-287093-9mertwj7	18	38	factories	factory	NNS
cord-287093-9mertwj7	18	39	and	and	CC
cord-287093-9mertwj7	18	40	viroplasm	viroplasm	NN
cord-287093-9mertwj7	18	41	and	and	CC
cord-287093-9mertwj7	18	42	the	the	DT
cord-287093-9mertwj7	18	43	cellular	cellular	JJ
cord-287093-9mertwj7	18	44	structures	structure	NNS
cord-287093-9mertwj7	18	45	that	that	WDT
cord-287093-9mertwj7	18	46	house	house	VBP
cord-287093-9mertwj7	18	47	them	-PRON-	PRP
cord-287093-9mertwj7	18	48	.	.	.
cord-287093-9mertwj7	19	1	In	in	IN
cord-287093-9mertwj7	19	2	this	this	DT
cord-287093-9mertwj7	19	3	review	review	NN
cord-287093-9mertwj7	19	4	,	,	,
cord-287093-9mertwj7	19	5	we	-PRON-	PRP
cord-287093-9mertwj7	19	6	discuss	discuss	VBP
cord-287093-9mertwj7	19	7	how	how	WRB
cord-287093-9mertwj7	19	8	three	three	CD
cord-287093-9mertwj7	19	9	supergroups	supergroup	NNS
cord-287093-9mertwj7	19	10	of	of	IN
cord-287093-9mertwj7	19	11	(	(	-LRB-
cord-287093-9mertwj7	19	12	+	+	CC
cord-287093-9mertwj7	19	13	)	)	-RRB-
cord-287093-9mertwj7	19	14	strand	strand	NN
cord-287093-9mertwj7	19	15	RNA	RNA	NNP
cord-287093-9mertwj7	19	16	viruses	virus	NNS
cord-287093-9mertwj7	19	17	generate	generate	VBP
cord-287093-9mertwj7	19	18	replication	replication	NN
cord-287093-9mertwj7	19	19	sites	site	NNS
cord-287093-9mertwj7	19	20	from	from	IN
cord-287093-9mertwj7	19	21	membrane	membrane	NN
cord-287093-9mertwj7	19	22	-	-	HYPH
cord-287093-9mertwj7	19	23	bound	bind	VBN
cord-287093-9mertwj7	19	24	organelles	organelle	NNS
cord-287093-9mertwj7	19	25	and	and	CC
cord-287093-9mertwj7	19	26	highlight	highlight	VBP
cord-287093-9mertwj7	19	27	research	research	NN
cord-287093-9mertwj7	19	28	on	on	IN
cord-287093-9mertwj7	19	29	perinuclear	perinuclear	NNP
cord-287093-9mertwj7	19	30	factories	factory	NNS
cord-287093-9mertwj7	19	31	induced	induce	VBN
cord-287093-9mertwj7	19	32	by	by	IN
cord-287093-9mertwj7	19	33	the	the	DT
cord-287093-9mertwj7	19	34	nucleocytoplasmic	nucleocytoplasmic	JJ
cord-287093-9mertwj7	19	35	large	large	JJ
cord-287093-9mertwj7	19	36	DNA	dna	NN
cord-287093-9mertwj7	19	37	viruses	virus	NNS
cord-287093-9mertwj7	19	38	(	(	-LRB-
cord-287093-9mertwj7	19	39	NCLDV	NCLDV	NNP
cord-287093-9mertwj7	19	40	)	)	-RRB-
cord-287093-9mertwj7	19	41	.	.	.
cord-287093-9mertwj7	20	1	The	the	DT
cord-287093-9mertwj7	20	2	RNA	RNA	NNP
cord-287093-9mertwj7	20	3	-	-	HYPH
cord-287093-9mertwj7	20	4	dependent	dependent	JJ
cord-287093-9mertwj7	20	5	RNA	RNA	NNP
cord-287093-9mertwj7	20	6	polymerases	polymerase	NNS
cord-287093-9mertwj7	20	7	(	(	-LRB-
cord-287093-9mertwj7	20	8	RdRp	RdRp	NNP
cord-287093-9mertwj7	20	9	)	)	-RRB-
cord-287093-9mertwj7	20	10	of	of	IN
cord-287093-9mertwj7	20	11	the	the	DT
cord-287093-9mertwj7	20	12	(	(	-LRB-
cord-287093-9mertwj7	20	13	+	+	CC
cord-287093-9mertwj7	20	14	)	)	-RRB-
cord-287093-9mertwj7	20	15	strand	strand	NN
cord-287093-9mertwj7	20	16	RNA	RNA	NNP
cord-287093-9mertwj7	20	17	viruses	virus	NNS
cord-287093-9mertwj7	20	18	are	be	VBP
cord-287093-9mertwj7	20	19	targeted	target	VBN
cord-287093-9mertwj7	20	20	to	to	IN
cord-287093-9mertwj7	20	21	the	the	DT
cord-287093-9mertwj7	20	22	cytoplasmic	cytoplasmic	JJ
cord-287093-9mertwj7	20	23	face	face	NN
cord-287093-9mertwj7	20	24	of	of	IN
cord-287093-9mertwj7	20	25	membrane	membrane	NN
cord-287093-9mertwj7	20	26	-	-	HYPH
cord-287093-9mertwj7	20	27	bound	bind	VBN
cord-287093-9mertwj7	20	28	organelles	organelle	NNS
cord-287093-9mertwj7	20	29	and	and	CC
cord-287093-9mertwj7	20	30	subsequent	subsequent	JJ
cord-287093-9mertwj7	20	31	assembly	assembly	NN
cord-287093-9mertwj7	20	32	of	of	IN
cord-287093-9mertwj7	20	33	the	the	DT
cord-287093-9mertwj7	20	34	replicase	replicase	NNP
cord-287093-9mertwj7	20	35	complex	complex	NN
cord-287093-9mertwj7	20	36	induces	induce	VBZ
cord-287093-9mertwj7	20	37	membrane	membrane	NN
cord-287093-9mertwj7	20	38	curvature	curvature	NN
cord-287093-9mertwj7	20	39	and	and	CC
cord-287093-9mertwj7	20	40	the	the	DT
cord-287093-9mertwj7	20	41	formation	formation	NN
cord-287093-9mertwj7	20	42	of	of	IN
cord-287093-9mertwj7	20	43	densely	densely	RB
cord-287093-9mertwj7	20	44	packed	pack	VBN
cord-287093-9mertwj7	20	45	membrane	membrane	NN
cord-287093-9mertwj7	20	46	vesicles	vesicle	NNS
cord-287093-9mertwj7	20	47	(	(	-LRB-
cord-287093-9mertwj7	20	48	reviewed	review	VBN
cord-287093-9mertwj7	20	49	in	in	IN
cord-287093-9mertwj7	20	50	[	[	-LRB-
cord-287093-9mertwj7	20	51	1	1	CD
cord-287093-9mertwj7	20	52	,	,	,
cord-287093-9mertwj7	20	53	2	2	CD
cord-287093-9mertwj7	20	54	]	]	-RRB-
cord-287093-9mertwj7	20	55	)	)	-RRB-
cord-287093-9mertwj7	21	1	(	(	-LRB-
cord-287093-9mertwj7	21	2	Figure	figure	NN
cord-287093-9mertwj7	21	3	1	1	CD
cord-287093-9mertwj7	21	4	)	)	-RRB-
cord-287093-9mertwj7	21	5	.	.	.
cord-287093-9mertwj7	22	1	The	the	DT
cord-287093-9mertwj7	22	2	alphaviruses	alphavirus	NNS
cord-287093-9mertwj7	22	3	generate	generate	VBP
cord-287093-9mertwj7	22	4	membrane	membrane	NN
cord-287093-9mertwj7	22	5	invaginations	invagination	NNS
cord-287093-9mertwj7	22	6	called	call	VBN
cord-287093-9mertwj7	22	7	spherules	spherules	NNP
cord-287093-9mertwj7	22	8	[	[	-LRB-
cord-287093-9mertwj7	22	9	3	3	CD
cord-287093-9mertwj7	22	10	]	]	-RRB-
cord-287093-9mertwj7	22	11	,	,	,
cord-287093-9mertwj7	22	12	while	while	IN
cord-287093-9mertwj7	22	13	the	the	DT
cord-287093-9mertwj7	22	14	flaviviruses	flavivirus	NNS
cord-287093-9mertwj7	22	15	and	and	CC
cord-287093-9mertwj7	22	16	coronaviruses	coronaviruse	NNS
cord-287093-9mertwj7	22	17	generate	generate	VBP
cord-287093-9mertwj7	22	18	networks	network	NNS
cord-287093-9mertwj7	22	19	of	of	IN
cord-287093-9mertwj7	22	20	double	double	JJ
cord-287093-9mertwj7	22	21	membrane	membrane	NN
cord-287093-9mertwj7	22	22	vesicles	vesicle	NNS
cord-287093-9mertwj7	22	23	(	(	-LRB-
cord-287093-9mertwj7	22	24	DMVs	dmv	NNS
cord-287093-9mertwj7	22	25	)	)	-RRB-
cord-287093-9mertwj7	22	26	connected	connect	VBN
cord-287093-9mertwj7	22	27	to	to	IN
cord-287093-9mertwj7	22	28	a	a	DT
cord-287093-9mertwj7	22	29	complex	complex	NN
cord-287093-9mertwj7	22	30	of	of	IN
cord-287093-9mertwj7	22	31	convoluted	convoluted	JJ
cord-287093-9mertwj7	22	32	membranes	membrane	NNS
cord-287093-9mertwj7	22	33	(	(	-LRB-
cord-287093-9mertwj7	22	34	CM	CM	NNP
cord-287093-9mertwj7	22	35	)	)	-RRB-
cord-287093-9mertwj7	22	36	derived	derive	VBN
cord-287093-9mertwj7	22	37	from	from	IN
cord-287093-9mertwj7	22	38	the	the	DT
cord-287093-9mertwj7	22	39	endoplasmic	endoplasmic	NN
cord-287093-9mertwj7	22	40	reticulum	reticulum	NN
cord-287093-9mertwj7	22	41	(	(	-LRB-
cord-287093-9mertwj7	22	42	ER	ER	NNP
cord-287093-9mertwj7	22	43	)	)	-RRB-
cord-287093-9mertwj7	22	44	.	.	.
cord-287093-9mertwj7	23	1	The	the	DT
cord-287093-9mertwj7	23	2	picornaviruses	picornavirus	NNS
cord-287093-9mertwj7	23	3	also	also	RB
cord-287093-9mertwj7	23	4	generate	generate	VBP
cord-287093-9mertwj7	23	5	DMVs	dmv	NNS
cord-287093-9mertwj7	23	6	and	and	CC
cord-287093-9mertwj7	23	7	a	a	DT
cord-287093-9mertwj7	23	8	heterogeneous	heterogeneous	JJ
cord-287093-9mertwj7	23	9	series	series	NN
cord-287093-9mertwj7	23	10	of	of	IN
cord-287093-9mertwj7	23	11	membrane	membrane	NN
cord-287093-9mertwj7	23	12	vesicles	vesicle	NNS
cord-287093-9mertwj7	23	13	and	and	CC
cord-287093-9mertwj7	23	14	membrane	membrane	NN
cord-287093-9mertwj7	23	15	rosettes	rosette	NNS
cord-287093-9mertwj7	23	16	[	[	-LRB-
cord-287093-9mertwj7	23	17	4	4	CD
cord-287093-9mertwj7	23	18	,	,	,
cord-287093-9mertwj7	23	19	5	5	CD
cord-287093-9mertwj7	23	20	]	]	-RRB-
cord-287093-9mertwj7	23	21	.	.	.
cord-287093-9mertwj7	24	1	The	the	DT
cord-287093-9mertwj7	24	2	formation	formation	NN
cord-287093-9mertwj7	24	3	of	of	IN
cord-287093-9mertwj7	24	4	spherules	spherule	NNS
cord-287093-9mertwj7	24	5	,	,	,
cord-287093-9mertwj7	24	6	and	and	CC
cord-287093-9mertwj7	24	7	possibly	possibly	RB
cord-287093-9mertwj7	24	8	DMVs	dmv	NNS
cord-287093-9mertwj7	24	9	,	,	,
cord-287093-9mertwj7	24	10	parallels	parallel	NNS
cord-287093-9mertwj7	24	11	mechanisms	mechanism	NNS
cord-287093-9mertwj7	24	12	of	of	IN
cord-287093-9mertwj7	24	13	capsid	capsid	NN
cord-287093-9mertwj7	24	14	assembly	assembly	NN
cord-287093-9mertwj7	24	15	where	where	WRB
cord-287093-9mertwj7	24	16	ordered	order	VBN
cord-287093-9mertwj7	24	17	assembly	assembly	NNP
cord-287093-9mertwj7	24	18	of	of	IN
cord-287093-9mertwj7	24	19	replicase	replicase	NNP
cord-287093-9mertwj7	24	20	proteins	protein	NNS
cord-287093-9mertwj7	24	21	induces	induce	VBZ
cord-287093-9mertwj7	24	22	membrane	membrane	NN
cord-287093-9mertwj7	24	23	curvature	curvature	NN
cord-287093-9mertwj7	24	24	and	and	CC
cord-287093-9mertwj7	24	25	invaginations	invagination	NNS
cord-287093-9mertwj7	24	26	of	of	IN
cord-287093-9mertwj7	24	27	uniform	uniform	JJ
cord-287093-9mertwj7	24	28	diameter	diameter	NN
cord-287093-9mertwj7	24	29	[	[	-LRB-
cord-287093-9mertwj7	24	30	2	2	CD
cord-287093-9mertwj7	24	31	]	]	-RRB-
cord-287093-9mertwj7	24	32	.	.	.
cord-287093-9mertwj7	25	1	The	the	DT
cord-287093-9mertwj7	25	2	more	more	RBR
cord-287093-9mertwj7	25	3	complex	complex	JJ
cord-287093-9mertwj7	25	4	membrane	membrane	NN
cord-287093-9mertwj7	25	5	rearrangements	rearrangement	NNS
cord-287093-9mertwj7	25	6	involving	involve	VBG
cord-287093-9mertwj7	25	7	ER	ER	NNP
cord-287093-9mertwj7	25	8	networks	network	NNS
cord-287093-9mertwj7	25	9	and	and	CC
cord-287093-9mertwj7	25	10	CM	CM	NNP
cord-287093-9mertwj7	25	11	may	may	MD
cord-287093-9mertwj7	25	12	involve	involve	VB
cord-287093-9mertwj7	25	13	additional	additional	JJ
cord-287093-9mertwj7	25	14	recruitment	recruitment	NN
cord-287093-9mertwj7	25	15	of	of	IN
cord-287093-9mertwj7	25	16	host	host	NN
cord-287093-9mertwj7	25	17	proteins	protein	NNS
cord-287093-9mertwj7	25	18	that	that	WDT
cord-287093-9mertwj7	25	19	modulate	modulate	VBP
cord-287093-9mertwj7	25	20	SNAP	snap	VB
cord-287093-9mertwj7	25	21	(	(	-LRB-
cord-287093-9mertwj7	25	22	Soluble	soluble	JJ
cord-287093-9mertwj7	25	23	NSF	NSF	NNP
cord-287093-9mertwj7	25	24	[	[	-LRB-
cord-287093-9mertwj7	25	25	N	n	CD
cord-287093-9mertwj7	25	26	-	-	HYPH
cord-287093-9mertwj7	25	27	ethylmaleimide	ethylmaleimide	JJ
cord-287093-9mertwj7	25	28	sensitive	sensitive	JJ
cord-287093-9mertwj7	25	29	factor	factor	NN
cord-287093-9mertwj7	25	30	]	]	-RRB-
cord-287093-9mertwj7	26	1	Attachment	Attachment	NNP
cord-287093-9mertwj7	26	2	Protein	Protein	NNP
cord-287093-9mertwj7	26	3	)	)	-RRB-
cord-287093-9mertwj7	26	4	Receptor	Receptor	NNP
cord-287093-9mertwj7	26	5	(	(	-LRB-
cord-287093-9mertwj7	26	6	SNARE	snare	NN
cord-287093-9mertwj7	26	7	)	)	-RRB-
cord-287093-9mertwj7	26	8	proteins	protein	NNS
cord-287093-9mertwj7	26	9	and	and	CC
cord-287093-9mertwj7	26	10	the	the	DT
cord-287093-9mertwj7	26	11	Rab	Rab	NNP
cord-287093-9mertwj7	26	12	and	and	CC
cord-287093-9mertwj7	26	13	Arf	Arf	NNP
cord-287093-9mertwj7	26	14	GTPases	GTPases	NNP
cord-287093-9mertwj7	26	15	that	that	WDT
cord-287093-9mertwj7	26	16	control	control	VBP
cord-287093-9mertwj7	26	17	the	the	DT
cord-287093-9mertwj7	26	18	secretory	secretory	JJ
cord-287093-9mertwj7	26	19	pathway	pathway	NN
cord-287093-9mertwj7	26	20	(	(	-LRB-
cord-287093-9mertwj7	26	21	reviewed	review	VBN
cord-287093-9mertwj7	26	22	in	in	IN
cord-287093-9mertwj7	26	23	[	[	-LRB-
cord-287093-9mertwj7	26	24	6	6	CD
cord-287093-9mertwj7	26	25	]	]	-RRB-
cord-287093-9mertwj7	26	26	)	)	-RRB-
cord-287093-9mertwj7	26	27	.	.	.
cord-287093-9mertwj7	27	1	RdRp	RdRp	NNP
cord-287093-9mertwj7	27	2	supergroup	supergroup	NN
cord-287093-9mertwj7	27	3	3	3	CD
cord-287093-9mertwj7	27	4	viruses	virus	NNS
cord-287093-9mertwj7	27	5	such	such	JJ
cord-287093-9mertwj7	27	6	as	as	IN
cord-287093-9mertwj7	27	7	the	the	DT
cord-287093-9mertwj7	27	8	animal	animal	NN
cord-287093-9mertwj7	27	9	alphaviruses	alphavirus	NNS
cord-287093-9mertwj7	27	10	,	,	,
cord-287093-9mertwj7	27	11	Semliki	Semliki	NNP
cord-287093-9mertwj7	27	12	Forest	Forest	NNP
cord-287093-9mertwj7	27	13	virus	virus	NN
cord-287093-9mertwj7	27	14	(	(	-LRB-
cord-287093-9mertwj7	27	15	SFV	SFV	NNP
cord-287093-9mertwj7	27	16	)	)	-RRB-
cord-287093-9mertwj7	27	17	and	and	CC
cord-287093-9mertwj7	28	1	Sindbis	sindbis	NN
cord-287093-9mertwj7	28	2	virus	virus	NN
cord-287093-9mertwj7	28	3	produce	produce	VBP
cord-287093-9mertwj7	28	4	50	50	CD
cord-287093-9mertwj7	28	5	nm	nm	NN
cord-287093-9mertwj7	28	6	diameter	diameter	NN
cord-287093-9mertwj7	28	7	invaginations	invagination	NNS
cord-287093-9mertwj7	28	8	called	call	VBD
cord-287093-9mertwj7	28	9	spherules	spherule	NNS
cord-287093-9mertwj7	28	10	that	that	WDT
cord-287093-9mertwj7	28	11	are	be	VBP
cord-287093-9mertwj7	28	12	aligned	align	VBN
cord-287093-9mertwj7	28	13	along	along	IN
cord-287093-9mertwj7	28	14	the	the	DT
cord-287093-9mertwj7	28	15	inside	inside	JJ
cord-287093-9mertwj7	28	16	face	face	NN
cord-287093-9mertwj7	28	17	of	of	IN
cord-287093-9mertwj7	28	18	the	the	DT
cord-287093-9mertwj7	28	19	limiting	limit	VBG
cord-287093-9mertwj7	28	20	membrane	membrane	NN
cord-287093-9mertwj7	28	21	of	of	IN
cord-287093-9mertwj7	28	22	endosomes	endosome	NNS
cord-287093-9mertwj7	28	23	and	and	CC
cord-287093-9mertwj7	28	24	lysosomes	lysosome	NNS
cord-287093-9mertwj7	28	25	[	[	-LRB-
cord-287093-9mertwj7	28	26	7	7	CD
cord-287093-9mertwj7	28	27	]	]	-RRB-
cord-287093-9mertwj7	28	28	.	.	.
cord-287093-9mertwj7	29	1	Flock	flock	NN
cord-287093-9mertwj7	29	2	house	house	NN
cord-287093-9mertwj7	29	3	virus	virus	NN
cord-287093-9mertwj7	29	4	(	(	-LRB-
cord-287093-9mertwj7	29	5	FHV	FHV	NNP
cord-287093-9mertwj7	29	6	)	)	-RRB-
cord-287093-9mertwj7	29	7	is	be	VBZ
cord-287093-9mertwj7	29	8	a	a	DT
cord-287093-9mertwj7	29	9	member	member	NN
cord-287093-9mertwj7	29	10	of	of	IN
cord-287093-9mertwj7	29	11	the	the	DT
cord-287093-9mertwj7	29	12	Nodaviridae	Nodaviridae	NNP
cord-287093-9mertwj7	29	13	family	family	NN
cord-287093-9mertwj7	29	14	(	(	-LRB-
cord-287093-9mertwj7	29	15	RdRp	RdRp	NNP
cord-287093-9mertwj7	29	16	supergroup	supergroup	NN
cord-287093-9mertwj7	29	17	1	1	CD
cord-287093-9mertwj7	29	18	)	)	-RRB-
cord-287093-9mertwj7	29	19	,	,	,
cord-287093-9mertwj7	29	20	which	which	WDT
cord-287093-9mertwj7	29	21	generates	generate	VBZ
cord-287093-9mertwj7	29	22	spherules	spherule	NNS
cord-287093-9mertwj7	29	23	in	in	IN
cord-287093-9mertwj7	29	24	the	the	DT
cord-287093-9mertwj7	29	25	outer	outer	JJ
cord-287093-9mertwj7	29	26	membrane	membrane	NN
cord-287093-9mertwj7	29	27	of	of	IN
cord-287093-9mertwj7	29	28	mitochondria	mitochondrion	NNS
cord-287093-9mertwj7	29	29	[	[	-LRB-
cord-287093-9mertwj7	29	30	8	8	CD
cord-287093-9mertwj7	29	31	]	]	-RRB-
cord-287093-9mertwj7	29	32	.	.	.
cord-287093-9mertwj7	30	1	Each	each	DT
cord-287093-9mertwj7	30	2	spherule	spherule	NN
cord-287093-9mertwj7	30	3	contains	contain	VBZ
cord-287093-9mertwj7	30	4	approximately	approximately	RB
cord-287093-9mertwj7	30	5	100	100	CD
cord-287093-9mertwj7	30	6	copies	copy	NNS
cord-287093-9mertwj7	30	7	of	of	IN
cord-287093-9mertwj7	30	8	the	the	DT
cord-287093-9mertwj7	30	9	replicase	replicase	NN
cord-287093-9mertwj7	30	10	protein	protein	NN
cord-287093-9mertwj7	30	11	packed	pack	VBN
cord-287093-9mertwj7	30	12	along	along	IN
cord-287093-9mertwj7	30	13	the	the	DT
cord-287093-9mertwj7	30	14	inner	inner	JJ
cord-287093-9mertwj7	30	15	membrane	membrane	NN
cord-287093-9mertwj7	30	16	surface	surface	NN
cord-287093-9mertwj7	30	17	[	[	-LRB-
cord-287093-9mertwj7	30	18	9	9	CD
cord-287093-9mertwj7	30	19	]	]	-RRB-
cord-287093-9mertwj7	30	20	.	.	.
cord-287093-9mertwj7	31	1	Tomographic	Tomographic	NNP
cord-287093-9mertwj7	31	2	Models	model	NNS
cord-287093-9mertwj7	31	3	for	for	IN
cord-287093-9mertwj7	31	4	formation	formation	NN
cord-287093-9mertwj7	31	5	of	of	IN
cord-287093-9mertwj7	31	6	sperules	sperule	NNS
cord-287093-9mertwj7	31	7	and	and	CC
cord-287093-9mertwj7	31	8	double	double	JJ
cord-287093-9mertwj7	31	9	membrane	membrane	NN
cord-287093-9mertwj7	31	10	vesicles	vesicle	NNS
cord-287093-9mertwj7	31	11	during	during	IN
cord-287093-9mertwj7	31	12	replication	replication	NN
cord-287093-9mertwj7	31	13	of	of	IN
cord-287093-9mertwj7	31	14	(	(	-LRB-
cord-287093-9mertwj7	31	15	+	+	CC
cord-287093-9mertwj7	31	16	)	)	-RRB-
cord-287093-9mertwj7	31	17	strand	strand	NN
cord-287093-9mertwj7	31	18	RNA	RNA	NNP
cord-287093-9mertwj7	31	19	viruses	virus	NNS
cord-287093-9mertwj7	31	20	.	.	.
cord-287093-9mertwj7	32	1	Panel	panel	NN
cord-287093-9mertwj7	32	2	1	1	CD
cord-287093-9mertwj7	32	3	:	:	:
cord-287093-9mertwj7	32	4	Spherule	Spherule	NNP
cord-287093-9mertwj7	32	5	produced	produce	VBN
cord-287093-9mertwj7	32	6	by	by	IN
cord-287093-9mertwj7	32	7	alphaviruses	alphavirus	NNS
cord-287093-9mertwj7	32	8	.	.	.
cord-287093-9mertwj7	33	1	Replicase	Replicase	NNP
cord-287093-9mertwj7	33	2	proteins	protein	NNS
cord-287093-9mertwj7	33	3	(	(	-LRB-
cord-287093-9mertwj7	33	4	red	red	JJ
cord-287093-9mertwj7	33	5	spheres	sphere	NNS
cord-287093-9mertwj7	33	6	)	)	-RRB-
cord-287093-9mertwj7	33	7	are	be	VBP
cord-287093-9mertwj7	33	8	recruited	recruit	VBN
cord-287093-9mertwj7	33	9	to	to	IN
cord-287093-9mertwj7	33	10	the	the	DT
cord-287093-9mertwj7	33	11	cytoplasmic	cytoplasmic	JJ
cord-287093-9mertwj7	33	12	face	face	NN
cord-287093-9mertwj7	33	13	of	of	IN
cord-287093-9mertwj7	33	14	membrane	membrane	NN
cord-287093-9mertwj7	33	15	-	-	HYPH
cord-287093-9mertwj7	33	16	bound	bind	VBN
cord-287093-9mertwj7	33	17	organelles	organelle	NNS
cord-287093-9mertwj7	33	18	.	.	.
cord-287093-9mertwj7	34	1	Assembly	Assembly	NNP
cord-287093-9mertwj7	34	2	of	of	IN
cord-287093-9mertwj7	34	3	replicase	replicase	NN
cord-287093-9mertwj7	34	4	proteins	protein	NNS
cord-287093-9mertwj7	34	5	induces	induce	VBZ
cord-287093-9mertwj7	34	6	membrane	membrane	NN
cord-287093-9mertwj7	34	7	curvature	curvature	NN
cord-287093-9mertwj7	34	8	and	and	CC
cord-287093-9mertwj7	34	9	invagination	invagination	NN
cord-287093-9mertwj7	34	10	forming	form	VBG
cord-287093-9mertwj7	34	11	a	a	DT
cord-287093-9mertwj7	34	12	spherule	spherule	NN
cord-287093-9mertwj7	34	13	.	.	.
cord-287093-9mertwj7	35	1	The	the	DT
cord-287093-9mertwj7	35	2	spherule	spherule	NN
cord-287093-9mertwj7	35	3	remains	remain	VBZ
cord-287093-9mertwj7	35	4	connected	connect	VBN
cord-287093-9mertwj7	35	5	to	to	IN
cord-287093-9mertwj7	35	6	the	the	DT
cord-287093-9mertwj7	35	7	limiting	limit	VBG
cord-287093-9mertwj7	35	8	membrane	membrane	NN
cord-287093-9mertwj7	35	9	of	of	IN
cord-287093-9mertwj7	35	10	the	the	DT
cord-287093-9mertwj7	35	11	organelle	organelle	NN
cord-287093-9mertwj7	35	12	and	and	CC
cord-287093-9mertwj7	35	13	a	a	DT
cord-287093-9mertwj7	35	14	pore	pore	NN
cord-287093-9mertwj7	35	15	allows	allow	VBZ
cord-287093-9mertwj7	35	16	new	new	JJ
cord-287093-9mertwj7	35	17	genomes	genome	NNS
cord-287093-9mertwj7	35	18	to	to	TO
cord-287093-9mertwj7	35	19	enter	enter	VB
cord-287093-9mertwj7	35	20	the	the	DT
cord-287093-9mertwj7	35	21	cytosol	cytosol	NN
cord-287093-9mertwj7	35	22	(	(	-LRB-
cord-287093-9mertwj7	35	23	adapted	adapt	VBN
cord-287093-9mertwj7	35	24	from	from	IN
cord-287093-9mertwj7	35	25	[	[	-LRB-
cord-287093-9mertwj7	35	26	2	2	CD
cord-287093-9mertwj7	35	27	]	]	-RRB-
cord-287093-9mertwj7	35	28	)	)	-RRB-
cord-287093-9mertwj7	35	29	.	.	.
cord-287093-9mertwj7	36	1	Panel	panel	NN
cord-287093-9mertwj7	36	2	2	2	CD
cord-287093-9mertwj7	36	3	:	:	:
cord-287093-9mertwj7	37	1	Virus	virus	NN
cord-287093-9mertwj7	37	2	-	-	HYPH
cord-287093-9mertwj7	37	3	induced	induce	VBN
cord-287093-9mertwj7	37	4	vesicles	vesicle	NNS
cord-287093-9mertwj7	37	5	and	and	CC
cord-287093-9mertwj7	37	6	double	double	JJ
cord-287093-9mertwj7	37	7	membrane	membrane	NN
cord-287093-9mertwj7	37	8	vesicles	vesicle	NNS
cord-287093-9mertwj7	37	9	generated	generate	VBN
cord-287093-9mertwj7	37	10	by	by	IN
cord-287093-9mertwj7	37	11	DENV	DENV	NNP
cord-287093-9mertwj7	37	12	flavivirus	flavivirus	NNP
cord-287093-9mertwj7	37	13	.	.	.
cord-287093-9mertwj7	38	1	Replicase	Replicase	NNP
cord-287093-9mertwj7	38	2	proteins	protein	NNS
cord-287093-9mertwj7	38	3	(	(	-LRB-
cord-287093-9mertwj7	38	4	red	red	JJ
cord-287093-9mertwj7	38	5	spheres	sphere	NNS
cord-287093-9mertwj7	38	6	)	)	-RRB-
cord-287093-9mertwj7	38	7	are	be	VBP
cord-287093-9mertwj7	38	8	recruited	recruit	VBN
cord-287093-9mertwj7	38	9	to	to	IN
cord-287093-9mertwj7	38	10	the	the	DT
cord-287093-9mertwj7	38	11	cytoplasmic	cytoplasmic	JJ
cord-287093-9mertwj7	38	12	face	face	NN
cord-287093-9mertwj7	38	13	of	of	IN
cord-287093-9mertwj7	38	14	membrane	membrane	NN
cord-287093-9mertwj7	38	15	-	-	HYPH
cord-287093-9mertwj7	38	16	bound	bind	VBN
cord-287093-9mertwj7	38	17	organelles	organelle	NNS
cord-287093-9mertwj7	38	18	.	.	.
cord-287093-9mertwj7	39	1	Assembly	Assembly	NNP
cord-287093-9mertwj7	39	2	of	of	IN
cord-287093-9mertwj7	39	3	replicase	replicase	NN
cord-287093-9mertwj7	39	4	proteins	protein	NNS
cord-287093-9mertwj7	39	5	induces	induce	VBZ
cord-287093-9mertwj7	39	6	membrane	membrane	NN
cord-287093-9mertwj7	39	7	curvature	curvature	NN
cord-287093-9mertwj7	39	8	and	and	CC
cord-287093-9mertwj7	39	9	invagination	invagination	NN
cord-287093-9mertwj7	39	10	into	into	IN
cord-287093-9mertwj7	39	11	the	the	DT
cord-287093-9mertwj7	39	12	ER	ER	NNP
cord-287093-9mertwj7	39	13	forming	form	VBG
cord-287093-9mertwj7	39	14	a	a	DT
cord-287093-9mertwj7	39	15	large	large	JJ
cord-287093-9mertwj7	39	16	spherule	spherule	NN
cord-287093-9mertwj7	39	17	.	.	.
cord-287093-9mertwj7	40	1	The	the	DT
cord-287093-9mertwj7	40	2	invagination	invagination	NN
cord-287093-9mertwj7	40	3	remains	remain	VBZ
cord-287093-9mertwj7	40	4	connected	connect	VBN
cord-287093-9mertwj7	40	5	to	to	IN
cord-287093-9mertwj7	40	6	the	the	DT
cord-287093-9mertwj7	40	7	limiting	limit	VBG
cord-287093-9mertwj7	40	8	membrane	membrane	NN
cord-287093-9mertwj7	40	9	of	of	IN
cord-287093-9mertwj7	40	10	the	the	DT
cord-287093-9mertwj7	40	11	organelle	organelle	NN
cord-287093-9mertwj7	40	12	and	and	CC
cord-287093-9mertwj7	40	13	a	a	DT
cord-287093-9mertwj7	40	14	pore	pore	NN
cord-287093-9mertwj7	40	15	allows	allow	VBZ
cord-287093-9mertwj7	40	16	new	new	JJ
cord-287093-9mertwj7	40	17	genomes	genome	NNS
cord-287093-9mertwj7	40	18	to	to	TO
cord-287093-9mertwj7	40	19	enter	enter	VB
cord-287093-9mertwj7	40	20	the	the	DT
cord-287093-9mertwj7	40	21	cytosol	cytosol	NN
cord-287093-9mertwj7	40	22	.	.	.
cord-287093-9mertwj7	41	1	Close	close	JJ
cord-287093-9mertwj7	41	2	apposition	apposition	NN
cord-287093-9mertwj7	41	3	of	of	IN
cord-287093-9mertwj7	41	4	ER	ER	NNP
cord-287093-9mertwj7	41	5	membranes	membrane	NNS
cord-287093-9mertwj7	41	6	leads	lead	VBZ
cord-287093-9mertwj7	41	7	to	to	IN
cord-287093-9mertwj7	41	8	the	the	DT
cord-287093-9mertwj7	41	9	formation	formation	NN
cord-287093-9mertwj7	41	10	of	of	IN
cord-287093-9mertwj7	41	11	DMVs	dmv	NNS
cord-287093-9mertwj7	41	12	connected	connect	VBN
cord-287093-9mertwj7	41	13	to	to	IN
cord-287093-9mertwj7	41	14	the	the	DT
cord-287093-9mertwj7	41	15	ER	ER	NNP
cord-287093-9mertwj7	41	16	by	by	IN
cord-287093-9mertwj7	41	17	convoluted	convoluted	JJ
cord-287093-9mertwj7	41	18	membranes	membrane	NNS
cord-287093-9mertwj7	41	19	(	(	-LRB-
cord-287093-9mertwj7	41	20	CM	CM	NNP
cord-287093-9mertwj7	41	21	)	)	-RRB-
cord-287093-9mertwj7	41	22	(	(	-LRB-
cord-287093-9mertwj7	41	23	adapted	adapt	VBN
cord-287093-9mertwj7	41	24	from	from	IN
cord-287093-9mertwj7	41	25	[	[	-LRB-
cord-287093-9mertwj7	41	26	10	10	CD
cord-287093-9mertwj7	41	27	]	]	-RRB-
cord-287093-9mertwj7	41	28	)	)	-RRB-
cord-287093-9mertwj7	41	29	.	.	.
cord-287093-9mertwj7	42	1	This	this	DT
cord-287093-9mertwj7	42	2	may	may	MD
cord-287093-9mertwj7	42	3	close	close	VB
cord-287093-9mertwj7	42	4	the	the	DT
cord-287093-9mertwj7	42	5	pore	pore	NN
cord-287093-9mertwj7	42	6	leading	lead	VBG
cord-287093-9mertwj7	42	7	to	to	IN
cord-287093-9mertwj7	42	8	the	the	DT
cord-287093-9mertwj7	42	9	cytosol	cytosol	NN
cord-287093-9mertwj7	42	10	.	.	.
cord-287093-9mertwj7	43	1	Panel	panel	NN
cord-287093-9mertwj7	43	2	3	3	CD
cord-287093-9mertwj7	43	3	:	:	:
cord-287093-9mertwj7	44	1	Virus	virus	NN
cord-287093-9mertwj7	44	2	-	-	HYPH
cord-287093-9mertwj7	44	3	induced	induce	VBN
cord-287093-9mertwj7	44	4	vesicles	vesicle	NNS
cord-287093-9mertwj7	44	5	and	and	CC
cord-287093-9mertwj7	44	6	double	double	JJ
cord-287093-9mertwj7	44	7	membrane	membrane	NN
cord-287093-9mertwj7	44	8	vesicles	vesicle	NNS
cord-287093-9mertwj7	44	9	generated	generate	VBN
cord-287093-9mertwj7	44	10	by	by	IN
cord-287093-9mertwj7	44	11	SARS	SARS	NNP
cord-287093-9mertwj7	44	12	-	-	HYPH
cord-287093-9mertwj7	44	13	CoV	CoV	NNP
cord-287093-9mertwj7	44	14	coronavirus	coronavirus	NN
cord-287093-9mertwj7	44	15	.	.	.
cord-287093-9mertwj7	45	1	Replicase	Replicase	NNP
cord-287093-9mertwj7	45	2	proteins	protein	NNS
cord-287093-9mertwj7	45	3	(	(	-LRB-
cord-287093-9mertwj7	45	4	red	red	JJ
cord-287093-9mertwj7	45	5	spheres	sphere	NNS
cord-287093-9mertwj7	45	6	)	)	-RRB-
cord-287093-9mertwj7	45	7	are	be	VBP
cord-287093-9mertwj7	45	8	recruited	recruit	VBN
cord-287093-9mertwj7	45	9	to	to	IN
cord-287093-9mertwj7	45	10	the	the	DT
cord-287093-9mertwj7	45	11	cytoplasmic	cytoplasmic	JJ
cord-287093-9mertwj7	45	12	face	face	NN
cord-287093-9mertwj7	45	13	of	of	IN
cord-287093-9mertwj7	45	14	membrane	membrane	NN
cord-287093-9mertwj7	45	15	-	-	HYPH
cord-287093-9mertwj7	45	16	bound	bind	VBN
cord-287093-9mertwj7	45	17	organelles	organelle	NNS
cord-287093-9mertwj7	45	18	.	.	.
cord-287093-9mertwj7	46	1	Assembly	Assembly	NNP
cord-287093-9mertwj7	46	2	of	of	IN
cord-287093-9mertwj7	46	3	replicase	replicase	NN
cord-287093-9mertwj7	46	4	proteins	protein	NNS
cord-287093-9mertwj7	46	5	induces	induce	VBZ
cord-287093-9mertwj7	46	6	membrane	membrane	NN
cord-287093-9mertwj7	46	7	curvature	curvature	NN
cord-287093-9mertwj7	46	8	and	and	CC
cord-287093-9mertwj7	46	9	invagination	invagination	NN
cord-287093-9mertwj7	46	10	into	into	IN
cord-287093-9mertwj7	46	11	the	the	DT
cord-287093-9mertwj7	46	12	ER	ER	NNP
cord-287093-9mertwj7	46	13	forming	form	VBG
cord-287093-9mertwj7	46	14	a	a	DT
cord-287093-9mertwj7	46	15	large	large	JJ
cord-287093-9mertwj7	46	16	spherule	spherule	NN
cord-287093-9mertwj7	46	17	.	.	.
cord-287093-9mertwj7	47	1	It	-PRON-	PRP
cord-287093-9mertwj7	47	2	has	have	VBZ
cord-287093-9mertwj7	47	3	been	be	VBN
cord-287093-9mertwj7	47	4	difficult	difficult	JJ
cord-287093-9mertwj7	47	5	to	to	TO
cord-287093-9mertwj7	47	6	find	find	VB
cord-287093-9mertwj7	47	7	evidence	evidence	NN
cord-287093-9mertwj7	47	8	for	for	IN
cord-287093-9mertwj7	47	9	a	a	DT
cord-287093-9mertwj7	47	10	pore	pore	NN
cord-287093-9mertwj7	47	11	connecting	connect	VBG
cord-287093-9mertwj7	47	12	invaginations	invagination	NNS
cord-287093-9mertwj7	47	13	to	to	IN
cord-287093-9mertwj7	47	14	cytosol	cytosol	NN
cord-287093-9mertwj7	47	15	.	.	.
cord-287093-9mertwj7	48	1	Close	close	JJ
cord-287093-9mertwj7	48	2	apposition	apposition	NN
cord-287093-9mertwj7	48	3	of	of	IN
cord-287093-9mertwj7	48	4	ER	ER	NNP
cord-287093-9mertwj7	48	5	membranes	membrane	NNS
cord-287093-9mertwj7	48	6	leads	lead	VBZ
cord-287093-9mertwj7	48	7	to	to	IN
cord-287093-9mertwj7	48	8	the	the	DT
cord-287093-9mertwj7	48	9	formation	formation	NN
cord-287093-9mertwj7	48	10	of	of	IN
cord-287093-9mertwj7	48	11	DMVs	dmv	NNS
cord-287093-9mertwj7	48	12	connected	connect	VBN
cord-287093-9mertwj7	48	13	to	to	IN
cord-287093-9mertwj7	48	14	the	the	DT
cord-287093-9mertwj7	48	15	ER	ER	NNP
cord-287093-9mertwj7	48	16	by	by	IN
cord-287093-9mertwj7	48	17	CM	CM	NNP
cord-287093-9mertwj7	48	18	.	.	.
cord-287093-9mertwj7	49	1	These	these	DT
cord-287093-9mertwj7	49	2	may	may	MD
cord-287093-9mertwj7	49	3	exclude	exclude	VB
cord-287093-9mertwj7	49	4	replicase	replicase	NN
cord-287093-9mertwj7	49	5	proteins	protein	NNS
cord-287093-9mertwj7	49	6	and	and	CC
cord-287093-9mertwj7	49	7	become	become	VBP
cord-287093-9mertwj7	49	8	sites	site	NNS
cord-287093-9mertwj7	49	9	for	for	IN
cord-287093-9mertwj7	49	10	storage	storage	NN
cord-287093-9mertwj7	49	11	of	of	IN
cord-287093-9mertwj7	49	12	viral	viral	JJ
cord-287093-9mertwj7	49	13	RNA	RNA	NNP
cord-287093-9mertwj7	49	14	.	.	.
cord-287093-9mertwj7	50	1	In	in	IN
cord-287093-9mertwj7	50	2	some	some	DT
cord-287093-9mertwj7	50	3	cases	case	NNS
cord-287093-9mertwj7	50	4	the	the	DT
cord-287093-9mertwj7	50	5	close	close	JJ
cord-287093-9mertwj7	50	6	apposition	apposition	NN
cord-287093-9mertwj7	50	7	of	of	IN
cord-287093-9mertwj7	50	8	ER	ER	NNP
cord-287093-9mertwj7	50	9	membranes	membrane	NNS
cord-287093-9mertwj7	50	10	is	be	VBZ
cord-287093-9mertwj7	50	11	lost	lose	VBN
cord-287093-9mertwj7	50	12	and	and	CC
cord-287093-9mertwj7	50	13	single	single	JJ
cord-287093-9mertwj7	50	14	membraned	membraned	JJ
cord-287093-9mertwj7	50	15	vesicles	vesicle	NNS
cord-287093-9mertwj7	50	16	arranged	arrange	VBN
cord-287093-9mertwj7	50	17	in	in	IN
cord-287093-9mertwj7	50	18	vesicle	vesicle	NN
cord-287093-9mertwj7	50	19	packets	packet	NNS
cord-287093-9mertwj7	50	20	(	(	-LRB-
cord-287093-9mertwj7	50	21	VP	VP	NNP
cord-287093-9mertwj7	50	22	)	)	-RRB-
cord-287093-9mertwj7	50	23	appear	appear	VBP
cord-287093-9mertwj7	50	24	within	within	IN
cord-287093-9mertwj7	50	25	membrane	membrane	NN
cord-287093-9mertwj7	50	26	networks	network	NNS
cord-287093-9mertwj7	50	27	connected	connect	VBN
cord-287093-9mertwj7	50	28	to	to	IN
cord-287093-9mertwj7	50	29	the	the	DT
cord-287093-9mertwj7	50	30	ER	ER	NNP
cord-287093-9mertwj7	50	31	(	(	-LRB-
cord-287093-9mertwj7	50	32	adapted	adapt	VBN
cord-287093-9mertwj7	50	33	from	from	IN
cord-287093-9mertwj7	50	34	[	[	-LRB-
cord-287093-9mertwj7	50	35	11	11	CD
cord-287093-9mertwj7	50	36	]	]	-RRB-
cord-287093-9mertwj7	50	37	)	)	-RRB-
cord-287093-9mertwj7	50	38	.	.	.
cord-287093-9mertwj7	51	1	reconstructions	reconstruction	NNS
cord-287093-9mertwj7	51	2	show	show	VBP
cord-287093-9mertwj7	51	3	that	that	IN
cord-287093-9mertwj7	51	4	spherule	spherule	JJ
cord-287093-9mertwj7	51	5	membranes	membrane	NNS
cord-287093-9mertwj7	51	6	are	be	VBP
cord-287093-9mertwj7	51	7	continuous	continuous	JJ
cord-287093-9mertwj7	51	8	with	with	IN
cord-287093-9mertwj7	51	9	the	the	DT
cord-287093-9mertwj7	51	10	outer	outer	JJ
cord-287093-9mertwj7	51	11	mitochondrial	mitochondrial	NN
cord-287093-9mertwj7	51	12	membrane	membrane	NN
cord-287093-9mertwj7	51	13	and	and	CC
cord-287093-9mertwj7	51	14	that	that	IN
cord-287093-9mertwj7	51	15	a	a	DT
cord-287093-9mertwj7	51	16	membrane	membrane	NN
cord-287093-9mertwj7	51	17	neck	neck	NN
cord-287093-9mertwj7	51	18	connecting	connect	VBG
cord-287093-9mertwj7	51	19	the	the	DT
cord-287093-9mertwj7	51	20	lumen	lumen	NN
cord-287093-9mertwj7	51	21	of	of	IN
cord-287093-9mertwj7	51	22	the	the	DT
cord-287093-9mertwj7	51	23	spherule	spherule	NNP
cord-287093-9mertwj7	51	24	to	to	IN
cord-287093-9mertwj7	51	25	the	the	DT
cord-287093-9mertwj7	51	26	cytosol	cytosol	NN
cord-287093-9mertwj7	51	27	surrounds	surround	VBZ
cord-287093-9mertwj7	51	28	a	a	DT
cord-287093-9mertwj7	51	29	channel	channel	NN
cord-287093-9mertwj7	51	30	wide	wide	RB
cord-287093-9mertwj7	51	31	enough	enough	RB
cord-287093-9mertwj7	51	32	to	to	TO
cord-287093-9mertwj7	51	33	allow	allow	VB
cord-287093-9mertwj7	51	34	passage	passage	NN
cord-287093-9mertwj7	51	35	of	of	IN
cord-287093-9mertwj7	51	36	(	(	-LRB-
cord-287093-9mertwj7	51	37	+	+	CC
cord-287093-9mertwj7	51	38	)	)	-RRB-
cord-287093-9mertwj7	51	39	RNA	RNA	NNP
cord-287093-9mertwj7	51	40	into	into	IN
cord-287093-9mertwj7	51	41	the	the	DT
cord-287093-9mertwj7	51	42	cytosol	cytosol	NN
cord-287093-9mertwj7	51	43	[	[	-LRB-
cord-287093-9mertwj7	51	44	9	9	CD
cord-287093-9mertwj7	51	45	]	]	-RRB-
cord-287093-9mertwj7	51	46	.	.	.
cord-287093-9mertwj7	52	1	Rubella	rubella	NN
cord-287093-9mertwj7	52	2	virus	virus	NN
cord-287093-9mertwj7	52	3	is	be	VBZ
cord-287093-9mertwj7	52	4	the	the	DT
cord-287093-9mertwj7	52	5	only	only	JJ
cord-287093-9mertwj7	52	6	member	member	NN
cord-287093-9mertwj7	52	7	of	of	IN
cord-287093-9mertwj7	52	8	the	the	DT
cord-287093-9mertwj7	52	9	Rubivirus	Rubivirus	NNP
cord-287093-9mertwj7	52	10	genus	genus	NN
cord-287093-9mertwj7	52	11	of	of	IN
cord-287093-9mertwj7	52	12	the	the	DT
cord-287093-9mertwj7	52	13	Togaviridae	Togaviridae	NNP
cord-287093-9mertwj7	52	14	,	,	,
cord-287093-9mertwj7	52	15	which	which	WDT
cord-287093-9mertwj7	52	16	are	be	VBP
cord-287093-9mertwj7	52	17	distantly	distantly	RB
cord-287093-9mertwj7	52	18	related	related	JJ
cord-287093-9mertwj7	52	19	to	to	IN
cord-287093-9mertwj7	52	20	the	the	DT
cord-287093-9mertwj7	52	21	alphaviruses	alphavirus	NNS
cord-287093-9mertwj7	52	22	.	.	.
cord-287093-9mertwj7	53	1	Assembly	assembly	NN
cord-287093-9mertwj7	53	2	of	of	IN
cord-287093-9mertwj7	53	3	the	the	DT
cord-287093-9mertwj7	53	4	rubella	rubella	NN
cord-287093-9mertwj7	53	5	RdRp	RdRp	NNP
cord-287093-9mertwj7	53	6	on	on	IN
cord-287093-9mertwj7	53	7	the	the	DT
cord-287093-9mertwj7	53	8	cytoplasmic	cytoplasmic	JJ
cord-287093-9mertwj7	53	9	face	face	NN
cord-287093-9mertwj7	53	10	of	of	IN
cord-287093-9mertwj7	53	11	endosomes	endosome	NNS
cord-287093-9mertwj7	53	12	and	and	CC
cord-287093-9mertwj7	53	13	lysosomes	lysosome	NNS
cord-287093-9mertwj7	53	14	generates	generate	VBZ
cord-287093-9mertwj7	53	15	spherules	spherule	NNS
cord-287093-9mertwj7	53	16	containing	contain	VBG
cord-287093-9mertwj7	53	17	replicase	replicase	NN
cord-287093-9mertwj7	53	18	proteins	protein	NNS
cord-287093-9mertwj7	53	19	and	and	CC
cord-287093-9mertwj7	53	20	double	double	RB
cord-287093-9mertwj7	53	21	-	-	HYPH
cord-287093-9mertwj7	53	22	stranded	strand	VBN
cord-287093-9mertwj7	53	23	RNA	RNA	NNP
cord-287093-9mertwj7	53	24	.	.	.
cord-287093-9mertwj7	54	1	In	in	IN
cord-287093-9mertwj7	54	2	some	some	DT
cord-287093-9mertwj7	54	3	cases	case	NNS
cord-287093-9mertwj7	54	4	,	,	,
cord-287093-9mertwj7	54	5	the	the	DT
cord-287093-9mertwj7	54	6	spherules	spherule	NNS
cord-287093-9mertwj7	54	7	grow	grow	VBP
cord-287093-9mertwj7	54	8	into	into	IN
cord-287093-9mertwj7	54	9	large	large	JJ
cord-287093-9mertwj7	54	10	vacuoles	vacuole	NNS
cord-287093-9mertwj7	54	11	and	and	CC
cord-287093-9mertwj7	54	12	rigid	rigid	JJ
cord-287093-9mertwj7	54	13	membrane	membrane	NN
cord-287093-9mertwj7	54	14	rods	rod	NNS
cord-287093-9mertwj7	54	15	and	and	CC
cord-287093-9mertwj7	54	16	sheets	sheet	NNS
cord-287093-9mertwj7	54	17	possibly	possibly	RB
cord-287093-9mertwj7	54	18	coated	coat	VBN
cord-287093-9mertwj7	54	19	with	with	IN
cord-287093-9mertwj7	54	20	RdRp	RdRp	NNP
cord-287093-9mertwj7	54	21	.	.	.
cord-287093-9mertwj7	55	1	Freeze	freeze	NN
cord-287093-9mertwj7	55	2	fracture	fracture	NN
cord-287093-9mertwj7	55	3	studies	study	NNS
cord-287093-9mertwj7	55	4	and	and	CC
cord-287093-9mertwj7	55	5	tomographic	tomographic	JJ
cord-287093-9mertwj7	55	6	reconstitution	reconstitution	NN
cord-287093-9mertwj7	55	7	have	have	VBP
cord-287093-9mertwj7	55	8	identified	identify	VBN
cord-287093-9mertwj7	55	9	inter	inter	JJ
cord-287093-9mertwj7	55	10	-	-	NNS
cord-287093-9mertwj7	55	11	connections	connection	NNS
cord-287093-9mertwj7	55	12	between	between	IN
cord-287093-9mertwj7	55	13	the	the	DT
cord-287093-9mertwj7	55	14	vacuoles	vacuole	NNS
cord-287093-9mertwj7	55	15	[	[	-LRB-
cord-287093-9mertwj7	55	16	7	7	CD
cord-287093-9mertwj7	55	17	]	]	-RRB-
cord-287093-9mertwj7	55	18	and	and	CC
cord-287093-9mertwj7	55	19	protein	protein	NN
cord-287093-9mertwj7	55	20	bridges	bridge	NNS
cord-287093-9mertwj7	55	21	connecting	connect	VBG
cord-287093-9mertwj7	55	22	vacuoles	vacuole	NNS
cord-287093-9mertwj7	55	23	to	to	IN
cord-287093-9mertwj7	55	24	ER	ER	NNP
cord-287093-9mertwj7	55	25	.	.	.
cord-287093-9mertwj7	56	1	The	the	DT
cord-287093-9mertwj7	56	2	flavivirus	flavivirus	JJ
cord-287093-9mertwj7	56	3	genus	genus	NN
cord-287093-9mertwj7	56	4	are	be	VBP
cord-287093-9mertwj7	56	5	part	part	NN
cord-287093-9mertwj7	56	6	of	of	IN
cord-287093-9mertwj7	56	7	RdRp	RdRp	NNP
cord-287093-9mertwj7	56	8	supergroup	supergroup	NN
cord-287093-9mertwj7	56	9	2	2	CD
cord-287093-9mertwj7	56	10	.	.	.
cord-287093-9mertwj7	57	1	Yellow	yellow	JJ
cord-287093-9mertwj7	57	2	fever	fever	NN
cord-287093-9mertwj7	57	3	virus	virus	NN
cord-287093-9mertwj7	57	4	,	,	,
cord-287093-9mertwj7	57	5	West	West	NNP
cord-287093-9mertwj7	57	6	Nile	Nile	NNP
cord-287093-9mertwj7	57	7	virus	virus	NN
cord-287093-9mertwj7	57	8	and	and	CC
cord-287093-9mertwj7	57	9	dengue	dengue	NN
cord-287093-9mertwj7	57	10	virus	virus	NN
cord-287093-9mertwj7	57	11	(	(	-LRB-
cord-287093-9mertwj7	57	12	DENV	DENV	NNP
cord-287093-9mertwj7	57	13	)	)	-RRB-
cord-287093-9mertwj7	57	14	generate	generate	VB
cord-287093-9mertwj7	57	15	80	80	CD
cord-287093-9mertwj7	57	16	-	-	SYM
cord-287093-9mertwj7	57	17	100	100	CD
cord-287093-9mertwj7	57	18	nm	nm	NN
cord-287093-9mertwj7	57	19	diameter	diameter	NN
cord-287093-9mertwj7	57	20	invaginations	invagination	NNS
cord-287093-9mertwj7	57	21	into	into	IN
cord-287093-9mertwj7	57	22	the	the	DT
cord-287093-9mertwj7	57	23	ER	ER	NNP
cord-287093-9mertwj7	57	24	.	.	.
cord-287093-9mertwj7	58	1	Tomographic	tomographic	JJ
cord-287093-9mertwj7	58	2	reconstructions	reconstruction	NNS
cord-287093-9mertwj7	58	3	of	of	IN
cord-287093-9mertwj7	58	4	membranes	membrane	NNS
cord-287093-9mertwj7	58	5	induced	induce	VBN
cord-287093-9mertwj7	58	6	by	by	IN
cord-287093-9mertwj7	58	7	DENV	DENV	NNP
cord-287093-9mertwj7	58	8	show	show	VBP
cord-287093-9mertwj7	58	9	a	a	DT
cord-287093-9mertwj7	58	10	continuous	continuous	JJ
cord-287093-9mertwj7	58	11	network	network	NN
cord-287093-9mertwj7	58	12	of	of	IN
cord-287093-9mertwj7	58	13	ER	ER	NNP
cord-287093-9mertwj7	58	14	membrane	membrane	NN
cord-287093-9mertwj7	58	15	connected	connect	VBN
cord-287093-9mertwj7	58	16	to	to	IN
cord-287093-9mertwj7	58	17	spherical	spherical	JJ
cord-287093-9mertwj7	58	18	vesicles	vesicle	NNS
cord-287093-9mertwj7	58	19	and	and	CC
cord-287093-9mertwj7	58	20	CM	CM	NNP
cord-287093-9mertwj7	58	21	[	[	-LRB-
cord-287093-9mertwj7	58	22	10	10	CD
cord-287093-9mertwj7	58	23	]	]	-RRB-
cord-287093-9mertwj7	58	24	.	.	.
cord-287093-9mertwj7	59	1	Virus	virus	NN
cord-287093-9mertwj7	59	2	-	-	HYPH
cord-287093-9mertwj7	59	3	induced	induce	VBN
cord-287093-9mertwj7	59	4	vesicles	vesicle	NNS
cord-287093-9mertwj7	59	5	contain	contain	VBP
cord-287093-9mertwj7	59	6	replicase	replicase	NN
cord-287093-9mertwj7	59	7	proteins	protein	NNS
cord-287093-9mertwj7	59	8	and	and	CC
cord-287093-9mertwj7	59	9	dsRNA	dsrna	NN
cord-287093-9mertwj7	59	10	and	and	CC
cord-287093-9mertwj7	59	11	are	be	VBP
cord-287093-9mertwj7	59	12	found	find	VBN
cord-287093-9mertwj7	59	13	within	within	IN
cord-287093-9mertwj7	59	14	the	the	DT
cord-287093-9mertwj7	59	15	lumen	lumen	NN
cord-287093-9mertwj7	59	16	of	of	IN
cord-287093-9mertwj7	59	17	the	the	DT
cord-287093-9mertwj7	59	18	ER	ER	NNP
cord-287093-9mertwj7	59	19	.	.	.
cord-287093-9mertwj7	60	1	Most	Most	JJS
cord-287093-9mertwj7	60	2	have	have	VBP
cord-287093-9mertwj7	60	3	double	double	JJ
cord-287093-9mertwj7	60	4	membranes	membrane	NNS
cord-287093-9mertwj7	60	5	suggesting	suggest	VBG
cord-287093-9mertwj7	60	6	that	that	IN
cord-287093-9mertwj7	60	7	they	-PRON-	PRP
cord-287093-9mertwj7	60	8	are	be	VBP
cord-287093-9mertwj7	60	9	formed	form	VBN
cord-287093-9mertwj7	60	10	from	from	IN
cord-287093-9mertwj7	60	11	invaginations	invagination	NNS
cord-287093-9mertwj7	60	12	into	into	IN
cord-287093-9mertwj7	60	13	ER	ER	NNP
cord-287093-9mertwj7	60	14	cisternae	cisternae	NNP
cord-287093-9mertwj7	60	15	[	[	-LRB-
cord-287093-9mertwj7	60	16	10	10	CD
cord-287093-9mertwj7	60	17	]	]	-RRB-
cord-287093-9mertwj7	60	18	.	.	.
cord-287093-9mertwj7	61	1	Each	each	DT
cord-287093-9mertwj7	61	2	spherical	spherical	JJ
cord-287093-9mertwj7	61	3	vesicle	vesicle	NN
cord-287093-9mertwj7	61	4	is	be	VBZ
cord-287093-9mertwj7	61	5	connected	connect	VBN
cord-287093-9mertwj7	61	6	to	to	IN
cord-287093-9mertwj7	61	7	the	the	DT
cord-287093-9mertwj7	61	8	ER	ER	NNP
cord-287093-9mertwj7	61	9	membrane	membrane	NN
cord-287093-9mertwj7	61	10	by	by	IN
cord-287093-9mertwj7	61	11	a	a	DT
cord-287093-9mertwj7	61	12	neck	neck	NN
cord-287093-9mertwj7	61	13	with	with	IN
cord-287093-9mertwj7	61	14	a	a	DT
cord-287093-9mertwj7	61	15	pore	pore	NN
cord-287093-9mertwj7	61	16	opening	opening	NN
cord-287093-9mertwj7	61	17	to	to	IN
cord-287093-9mertwj7	61	18	the	the	DT
cord-287093-9mertwj7	61	19	cytosol	cytosol	NN
cord-287093-9mertwj7	61	20	that	that	WDT
cord-287093-9mertwj7	61	21	could	could	MD
cord-287093-9mertwj7	61	22	allow	allow	VB
cord-287093-9mertwj7	61	23	transit	transit	NN
cord-287093-9mertwj7	61	24	of	of	IN
cord-287093-9mertwj7	61	25	viral	viral	JJ
cord-287093-9mertwj7	61	26	RNA	RNA	NNP
cord-287093-9mertwj7	61	27	.	.	.
cord-287093-9mertwj7	62	1	In	in	IN
cord-287093-9mertwj7	62	2	some	some	DT
cord-287093-9mertwj7	62	3	images	image	NNS
cord-287093-9mertwj7	62	4	,	,	,
cord-287093-9mertwj7	62	5	the	the	DT
cord-287093-9mertwj7	62	6	pores	pore	NNS
cord-287093-9mertwj7	62	7	lie	lie	VBP
cord-287093-9mertwj7	62	8	adjacent	adjacent	JJ
cord-287093-9mertwj7	62	9	to	to	IN
cord-287093-9mertwj7	62	10	sites	site	NNS
cord-287093-9mertwj7	62	11	of	of	IN
cord-287093-9mertwj7	62	12	virus	virus	NN
cord-287093-9mertwj7	62	13	assembly	assembly	NN
cord-287093-9mertwj7	62	14	making	make	VBG
cord-287093-9mertwj7	62	15	it	-PRON-	PRP
cord-287093-9mertwj7	62	16	possible	possible	JJ
cord-287093-9mertwj7	62	17	that	that	IN
cord-287093-9mertwj7	62	18	viral	viral	JJ
cord-287093-9mertwj7	62	19	RNA	RNA	NNP
cord-287093-9mertwj7	62	20	passes	pass	VBZ
cord-287093-9mertwj7	62	21	directly	directly	RB
cord-287093-9mertwj7	62	22	from	from	IN
cord-287093-9mertwj7	62	23	the	the	DT
cord-287093-9mertwj7	62	24	spherical	spherical	JJ
cord-287093-9mertwj7	62	25	vesicles	vesicle	NNS
cord-287093-9mertwj7	62	26	to	to	IN
cord-287093-9mertwj7	62	27	budding	bud	VBG
cord-287093-9mertwj7	62	28	viruses	virus	NNS
cord-287093-9mertwj7	62	29	[	[	-LRB-
cord-287093-9mertwj7	62	30	10	10	CD
cord-287093-9mertwj7	62	31	]	]	-RRB-
cord-287093-9mertwj7	62	32	.	.	.
cord-287093-9mertwj7	63	1	Arterivirus	Arterivirus	NNP
cord-287093-9mertwj7	63	2	and	and	CC
cord-287093-9mertwj7	63	3	coronaviruses	coronaviruse	NNS
cord-287093-9mertwj7	63	4	also	also	RB
cord-287093-9mertwj7	63	5	generate	generate	VBP
cord-287093-9mertwj7	63	6	densely	densely	RB
cord-287093-9mertwj7	63	7	packed	pack	VBN
cord-287093-9mertwj7	63	8	membrane	membrane	NN
cord-287093-9mertwj7	63	9	vesicles	vesicle	NNS
cord-287093-9mertwj7	63	10	.	.	.
cord-287093-9mertwj7	64	1	Three	three	CD
cord-287093-9mertwj7	64	2	-	-	HYPH
cord-287093-9mertwj7	64	3	dimensional	dimensional	JJ
cord-287093-9mertwj7	64	4	reconstructions	reconstruction	NNS
cord-287093-9mertwj7	64	5	of	of	IN
cord-287093-9mertwj7	64	6	vesicles	vesicle	NNS
cord-287093-9mertwj7	64	7	induced	induce	VBN
cord-287093-9mertwj7	64	8	by	by	IN
cord-287093-9mertwj7	64	9	severe	severe	JJ
cord-287093-9mertwj7	64	10	acute	acute	JJ
cord-287093-9mertwj7	64	11	respiratory	respiratory	JJ
cord-287093-9mertwj7	64	12	syndrome	syndrome	NN
cord-287093-9mertwj7	64	13	coronavirus	coronavirus	NN
cord-287093-9mertwj7	64	14	(	(	-LRB-
cord-287093-9mertwj7	64	15	SARS	SARS	NNP
cord-287093-9mertwj7	64	16	-	-	HYPH
cord-287093-9mertwj7	64	17	CoV	CoV	NNP
cord-287093-9mertwj7	64	18	)	)	-RRB-
cord-287093-9mertwj7	64	19	show	show	VBP
cord-287093-9mertwj7	64	20	DMVs	dmv	NNS
cord-287093-9mertwj7	64	21	between	between	IN
cord-287093-9mertwj7	64	22	150	150	CD
cord-287093-9mertwj7	64	23	and	and	CC
cord-287093-9mertwj7	64	24	300	300	CD
cord-287093-9mertwj7	64	25	nm	nm	NN
cord-287093-9mertwj7	64	26	in	in	IN
cord-287093-9mertwj7	64	27	size	size	NN
cord-287093-9mertwj7	64	28	bounded	bound	VBN
cord-287093-9mertwj7	64	29	by	by	IN
cord-287093-9mertwj7	64	30	two	two	CD
cord-287093-9mertwj7	64	31	tightly	tightly	RB
cord-287093-9mertwj7	64	32	apposed	apposed	JJ
cord-287093-9mertwj7	64	33	membranes	membrane	NNS
cord-287093-9mertwj7	64	34	connected	connect	VBN
cord-287093-9mertwj7	64	35	to	to	IN
cord-287093-9mertwj7	64	36	ER	ER	NNP
cord-287093-9mertwj7	64	37	[	[	-LRB-
cord-287093-9mertwj7	64	38	11	11	CD
cord-287093-9mertwj7	64	39	]	]	-RRB-
cord-287093-9mertwj7	64	40	.	.	.
cord-287093-9mertwj7	65	1	SARS	SARS	NNP
cord-287093-9mertwj7	65	2	-	-	HYPH
cord-287093-9mertwj7	65	3	CoV	CoV	NNP
cord-287093-9mertwj7	65	4	also	also	RB
cord-287093-9mertwj7	65	5	induces	induce	VBZ
cord-287093-9mertwj7	65	6	CM	cm	NN
cord-287093-9mertwj7	65	7	containing	contain	VBG
cord-287093-9mertwj7	65	8	small	small	JJ
cord-287093-9mertwj7	65	9	tubular	tubular	JJ
cord-287093-9mertwj7	65	10	and	and	CC
cord-287093-9mertwj7	65	11	reticular	reticular	JJ
cord-287093-9mertwj7	65	12	membranes	membrane	NNS
cord-287093-9mertwj7	65	13	connected	connect	VBN
cord-287093-9mertwj7	65	14	to	to	IN
cord-287093-9mertwj7	65	15	the	the	DT
cord-287093-9mertwj7	65	16	ER	ER	NNP
cord-287093-9mertwj7	65	17	.	.	.
cord-287093-9mertwj7	66	1	Later	later	RB
cord-287093-9mertwj7	66	2	during	during	IN
cord-287093-9mertwj7	66	3	infection	infection	NN
cord-287093-9mertwj7	66	4	cells	cell	NNS
cord-287093-9mertwj7	66	5	contain	contain	VBP
cord-287093-9mertwj7	66	6	'	'	``
cord-287093-9mertwj7	66	7	vesicular	vesicular	JJ
cord-287093-9mertwj7	66	8	packets	packet	NNS
cord-287093-9mertwj7	66	9	'	'	''
cord-287093-9mertwj7	66	10	where	where	WRB
cord-287093-9mertwj7	66	11	single	single	JJ
cord-287093-9mertwj7	66	12	membraned	membraned	JJ
cord-287093-9mertwj7	66	13	vesicles	vesicle	NNS
cord-287093-9mertwj7	66	14	are	be	VBP
cord-287093-9mertwj7	66	15	surrounded	surround	VBN
cord-287093-9mertwj7	66	16	by	by	IN
cord-287093-9mertwj7	66	17	a	a	DT
cord-287093-9mertwj7	66	18	common	common	JJ
cord-287093-9mertwj7	66	19	outer	outer	JJ
cord-287093-9mertwj7	66	20	ER	ER	NNP
cord-287093-9mertwj7	66	21	membrane	membrane	NN
cord-287093-9mertwj7	66	22	[	[	-LRB-
cord-287093-9mertwj7	66	23	11	11	CD
cord-287093-9mertwj7	66	24	]	]	-RRB-
cord-287093-9mertwj7	66	25	.	.	.
cord-287093-9mertwj7	67	1	The	the	DT
cord-287093-9mertwj7	67	2	interior	interior	NN
cord-287093-9mertwj7	67	3	of	of	IN
cord-287093-9mertwj7	67	4	the	the	DT
cord-287093-9mertwj7	67	5	DMVs	dmv	NNS
cord-287093-9mertwj7	67	6	contains	contain	VBZ
cord-287093-9mertwj7	67	7	dsRNA	dsrna	JJ
cord-287093-9mertwj7	68	1	but	but	CC
cord-287093-9mertwj7	68	2	surprisingly	surprisingly	RB
cord-287093-9mertwj7	68	3	,	,	,
cord-287093-9mertwj7	68	4	unlike	unlike	IN
cord-287093-9mertwj7	68	5	DMVs	dmv	NNS
cord-287093-9mertwj7	68	6	generated	generate	VBN
cord-287093-9mertwj7	68	7	by	by	IN
cord-287093-9mertwj7	68	8	flaviviruses	flavivirus	NNS
cord-287093-9mertwj7	68	9	,	,	,
cord-287093-9mertwj7	68	10	the	the	DT
cord-287093-9mertwj7	68	11	replicase	replicase	NN
cord-287093-9mertwj7	68	12	proteins	protein	NNS
cord-287093-9mertwj7	68	13	are	be	VBP
cord-287093-9mertwj7	68	14	absent	absent	JJ
cord-287093-9mertwj7	68	15	from	from	IN
cord-287093-9mertwj7	68	16	the	the	DT
cord-287093-9mertwj7	68	17	DMVs	dmv	NNS
cord-287093-9mertwj7	68	18	but	but	CC
cord-287093-9mertwj7	68	19	locate	locate	VB
cord-287093-9mertwj7	68	20	to	to	IN
cord-287093-9mertwj7	68	21	the	the	DT
cord-287093-9mertwj7	68	22	CM	cm	NN
cord-287093-9mertwj7	68	23	that	that	WDT
cord-287093-9mertwj7	68	24	lie	lie	NN
cord-287093-9mertwj7	68	25	between	between	IN
cord-287093-9mertwj7	68	26	DMVs	dmv	NNS
cord-287093-9mertwj7	68	27	.	.	.
cord-287093-9mertwj7	69	1	This	this	DT
cord-287093-9mertwj7	69	2	suggests	suggest	VBZ
cord-287093-9mertwj7	69	3	that	that	IN
cord-287093-9mertwj7	69	4	virus	virus	NN
cord-287093-9mertwj7	69	5	replication	replication	NN
cord-287093-9mertwj7	69	6	occurs	occur	VBZ
cord-287093-9mertwj7	69	7	in	in	IN
cord-287093-9mertwj7	69	8	the	the	DT
cord-287093-9mertwj7	69	9	CM	cm	NN
cord-287093-9mertwj7	69	10	rather	rather	RB
cord-287093-9mertwj7	69	11	than	than	IN
cord-287093-9mertwj7	69	12	DMVs	dmv	NNS
cord-287093-9mertwj7	69	13	.	.	.
cord-287093-9mertwj7	70	1	Neck	neck	NN
cord-287093-9mertwj7	70	2	-	-	HYPH
cord-287093-9mertwj7	70	3	like	like	JJ
cord-287093-9mertwj7	70	4	structures	structure	NNS
cord-287093-9mertwj7	70	5	extending	extend	VBG
cord-287093-9mertwj7	70	6	from	from	IN
cord-287093-9mertwj7	70	7	DMVs	dmv	NNS
cord-287093-9mertwj7	70	8	to	to	IN
cord-287093-9mertwj7	70	9	the	the	DT
cord-287093-9mertwj7	70	10	outer	outer	JJ
cord-287093-9mertwj7	70	11	ER	ER	NNP
cord-287093-9mertwj7	70	12	membrane	membrane	NN
cord-287093-9mertwj7	70	13	are	be	VBP
cord-287093-9mertwj7	70	14	visible	visible	JJ
cord-287093-9mertwj7	70	15	,	,	,
cord-287093-9mertwj7	70	16	but	but	CC
cord-287093-9mertwj7	70	17	evidence	evidence	NN
cord-287093-9mertwj7	70	18	for	for	IN
cord-287093-9mertwj7	70	19	a	a	DT
cord-287093-9mertwj7	70	20	pore	pore	NN
cord-287093-9mertwj7	70	21	connected	connect	VBN
cord-287093-9mertwj7	70	22	to	to	IN
cord-287093-9mertwj7	70	23	the	the	DT
cord-287093-9mertwj7	70	24	cytosol	cytosol	NN
cord-287093-9mertwj7	70	25	is	be	VBZ
cord-287093-9mertwj7	70	26	lacking	lack	VBG
cord-287093-9mertwj7	70	27	.	.	.
cord-287093-9mertwj7	71	1	Enveloped	Enveloped	NNP
cord-287093-9mertwj7	71	2	SARS	SARS	NNP
cord-287093-9mertwj7	71	3	-	-	HYPH
cord-287093-9mertwj7	71	4	CoV	CoV	NNP
cord-287093-9mertwj7	71	5	can	can	MD
cord-287093-9mertwj7	71	6	be	be	VB
cord-287093-9mertwj7	71	7	detected	detect	VBN
cord-287093-9mertwj7	71	8	in	in	IN
cord-287093-9mertwj7	71	9	the	the	DT
cord-287093-9mertwj7	71	10	vesicular	vesicular	JJ
cord-287093-9mertwj7	71	11	packets	packet	NNS
cord-287093-9mertwj7	71	12	.	.	.
cord-287093-9mertwj7	72	1	This	this	DT
cord-287093-9mertwj7	72	2	suggests	suggest	VBZ
cord-287093-9mertwj7	72	3	that	that	IN
cord-287093-9mertwj7	72	4	replication	replication	NN
cord-287093-9mertwj7	72	5	may	may	MD
cord-287093-9mertwj7	72	6	take	take	VB
cord-287093-9mertwj7	72	7	place	place	NN
cord-287093-9mertwj7	72	8	on	on	IN
cord-287093-9mertwj7	72	9	CM	cm	NN
cord-287093-9mertwj7	72	10	and	and	CC
cord-287093-9mertwj7	72	11	that	that	IN
cord-287093-9mertwj7	72	12	genomes	genome	NNS
cord-287093-9mertwj7	72	13	are	be	VBP
cord-287093-9mertwj7	72	14	transferred	transfer	VBN
cord-287093-9mertwj7	72	15	to	to	IN
cord-287093-9mertwj7	72	16	vesicular	vesicular	JJ
cord-287093-9mertwj7	72	17	packets	packet	NNS
cord-287093-9mertwj7	72	18	for	for	IN
cord-287093-9mertwj7	72	19	envelopment	envelopment	NN
cord-287093-9mertwj7	72	20	and	and	CC
cord-287093-9mertwj7	72	21	budding	budding	NN
cord-287093-9mertwj7	72	22	,	,	,
cord-287093-9mertwj7	72	23	while	while	IN
cord-287093-9mertwj7	72	24	excess	excess	JJ
cord-287093-9mertwj7	72	25	viral	viral	JJ
cord-287093-9mertwj7	72	26	RNA	RNA	NNP
cord-287093-9mertwj7	72	27	may	may	MD
cord-287093-9mertwj7	72	28	be	be	VB
cord-287093-9mertwj7	72	29	stored	store	VBN
cord-287093-9mertwj7	72	30	in	in	IN
cord-287093-9mertwj7	72	31	DMVs	dmv	NNS
cord-287093-9mertwj7	72	32	.	.	.
cord-287093-9mertwj7	73	1	Picornaviruses	picornavirus	NNS
cord-287093-9mertwj7	73	2	generate	generate	VBP
cord-287093-9mertwj7	73	3	densely	densely	RB
cord-287093-9mertwj7	73	4	packed	pack	VBN
cord-287093-9mertwj7	73	5	DMVs	dmv	NNS
cord-287093-9mertwj7	73	6	between	between	IN
cord-287093-9mertwj7	73	7	200	200	CD
cord-287093-9mertwj7	73	8	and	and	CC
cord-287093-9mertwj7	73	9	400	400	CD
cord-287093-9mertwj7	73	10	nm	nm	NN
cord-287093-9mertwj7	73	11	in	in	IN
cord-287093-9mertwj7	73	12	diameter	diameter	NN
cord-287093-9mertwj7	73	13	,	,	,
cord-287093-9mertwj7	73	14	a	a	DT
cord-287093-9mertwj7	73	15	series	series	NN
cord-287093-9mertwj7	73	16	of	of	IN
cord-287093-9mertwj7	73	17	single	single	JJ
cord-287093-9mertwj7	73	18	membraned	membraned	JJ
cord-287093-9mertwj7	73	19	vesicles	vesicle	NNS
cord-287093-9mertwj7	73	20	resulting	result	VBG
cord-287093-9mertwj7	73	21	from	from	IN
cord-287093-9mertwj7	73	22	fragmentation	fragmentation	NN
cord-287093-9mertwj7	73	23	of	of	IN
cord-287093-9mertwj7	73	24	the	the	DT
cord-287093-9mertwj7	73	25	Golgi	Golgi	NNP
cord-287093-9mertwj7	73	26	,	,	,
cord-287093-9mertwj7	73	27	and	and	CC
cord-287093-9mertwj7	73	28	autophagosomes	autophagosomes	NNP
cord-287093-9mertwj7	73	29	possibly	possibly	RB
cord-287093-9mertwj7	73	30	generated	generate	VBN
cord-287093-9mertwj7	73	31	as	as	IN
cord-287093-9mertwj7	73	32	a	a	DT
cord-287093-9mertwj7	73	33	bystander	bystander	NN
cord-287093-9mertwj7	73	34	response	response	NN
cord-287093-9mertwj7	73	35	to	to	IN
cord-287093-9mertwj7	73	36	infection	infection	NN
cord-287093-9mertwj7	73	37	[	[	-LRB-
cord-287093-9mertwj7	73	38	11	11	CD
cord-287093-9mertwj7	73	39	,	,	,
cord-287093-9mertwj7	73	40	12	12	CD
cord-287093-9mertwj7	73	41	-	-	SYM
cord-287093-9mertwj7	73	42	16	16	CD
cord-287093-9mertwj7	73	43	]	]	-RRB-
cord-287093-9mertwj7	73	44	.	.	.
cord-287093-9mertwj7	74	1	The	the	DT
cord-287093-9mertwj7	74	2	nature	nature	NN
cord-287093-9mertwj7	74	3	and	and	CC
cord-287093-9mertwj7	74	4	relative	relative	JJ
cord-287093-9mertwj7	74	5	numbers	number	NNS
cord-287093-9mertwj7	74	6	of	of	IN
cord-287093-9mertwj7	74	7	vesicles	vesicle	NNS
cord-287093-9mertwj7	74	8	vary	vary	VBP
cord-287093-9mertwj7	74	9	greatly	greatly	RB
cord-287093-9mertwj7	74	10	depending	depend	VBG
cord-287093-9mertwj7	74	11	on	on	IN
cord-287093-9mertwj7	74	12	the	the	DT
cord-287093-9mertwj7	74	13	picornavirus	picornavirus	NNP
cord-287093-9mertwj7	74	14	family	family	NN
cord-287093-9mertwj7	74	15	and	and	CC
cord-287093-9mertwj7	74	16	it	-PRON-	PRP
cord-287093-9mertwj7	74	17	is	be	VBZ
cord-287093-9mertwj7	74	18	not	not	RB
cord-287093-9mertwj7	74	19	clear	clear	JJ
cord-287093-9mertwj7	74	20	which	which	WDT
cord-287093-9mertwj7	74	21	population	population	NN
cord-287093-9mertwj7	74	22	of	of	IN
cord-287093-9mertwj7	74	23	vesicles	vesicle	NNS
cord-287093-9mertwj7	74	24	house	house	VBP
cord-287093-9mertwj7	74	25	the	the	DT
cord-287093-9mertwj7	74	26	replication	replication	NN
cord-287093-9mertwj7	74	27	complex	complex	NN
cord-287093-9mertwj7	74	28	.	.	.
cord-287093-9mertwj7	75	1	The	the	DT
cord-287093-9mertwj7	75	2	DMVs	dmv	NNS
cord-287093-9mertwj7	75	3	generated	generate	VBN
cord-287093-9mertwj7	75	4	during	during	IN
cord-287093-9mertwj7	75	5	picornavirus	picornavirus	NNP
cord-287093-9mertwj7	75	6	replication	replication	NN
cord-287093-9mertwj7	75	7	lack	lack	VBP
cord-287093-9mertwj7	75	8	an	an	DT
cord-287093-9mertwj7	75	9	obvious	obvious	JJ
cord-287093-9mertwj7	75	10	opening	opening	NN
cord-287093-9mertwj7	75	11	to	to	IN
cord-287093-9mertwj7	75	12	the	the	DT
cord-287093-9mertwj7	75	13	cytosol	cytosol	NN
cord-287093-9mertwj7	75	14	making	make	VBG
cord-287093-9mertwj7	75	15	it	-PRON-	PRP
cord-287093-9mertwj7	75	16	possible	possible	JJ
cord-287093-9mertwj7	75	17	that	that	IN
cord-287093-9mertwj7	75	18	,	,	,
cord-287093-9mertwj7	75	19	as	as	IN
cord-287093-9mertwj7	75	20	suggested	suggest	VBN
cord-287093-9mertwj7	75	21	for	for	IN
cord-287093-9mertwj7	75	22	coronaviruses	coronaviruse	NNS
cord-287093-9mertwj7	75	23	,	,	,
cord-287093-9mertwj7	75	24	they	-PRON-	PRP
cord-287093-9mertwj7	75	25	are	be	VBP
cord-287093-9mertwj7	75	26	a	a	DT
cord-287093-9mertwj7	75	27	by	by	IN
cord-287093-9mertwj7	75	28	-	-	HYPH
cord-287093-9mertwj7	75	29	product	product	NN
cord-287093-9mertwj7	75	30	of	of	IN
cord-287093-9mertwj7	75	31	replicase	replicase	NNP
cord-287093-9mertwj7	75	32	assembly	assembly	NNP
cord-287093-9mertwj7	75	33	and	and	CC
cord-287093-9mertwj7	75	34	are	be	VBP
cord-287093-9mertwj7	75	35	used	use	VBN
cord-287093-9mertwj7	75	36	as	as	IN
cord-287093-9mertwj7	75	37	a	a	DT
cord-287093-9mertwj7	75	38	storage	storage	NN
cord-287093-9mertwj7	75	39	site	site	NN
cord-287093-9mertwj7	75	40	for	for	IN
cord-287093-9mertwj7	75	41	viral	viral	JJ
cord-287093-9mertwj7	75	42	RNA	RNA	NNP
cord-287093-9mertwj7	75	43	.	.	.
cord-287093-9mertwj7	76	1	Lipid	lipid	NN
cord-287093-9mertwj7	76	2	biosynthesis	biosynthesis	NN
cord-287093-9mertwj7	76	3	plays	play	VBZ
cord-287093-9mertwj7	76	4	an	an	DT
cord-287093-9mertwj7	76	5	important	important	JJ
cord-287093-9mertwj7	76	6	role	role	NN
cord-287093-9mertwj7	76	7	in	in	IN
cord-287093-9mertwj7	76	8	both	both	DT
cord-287093-9mertwj7	76	9	alphavirus	alphavirus	NNP
cord-287093-9mertwj7	76	10	replication	replication	NN
cord-287093-9mertwj7	76	11	and	and	CC
cord-287093-9mertwj7	76	12	nodavirus	nodavirus	NN
cord-287093-9mertwj7	76	13	replication	replication	NN
cord-287093-9mertwj7	76	14	as	as	IN
cord-287093-9mertwj7	76	15	cerulenin	cerulenin	JJ
cord-287093-9mertwj7	76	16	treatment	treatment	NN
cord-287093-9mertwj7	76	17	inhibits	inhibit	VBZ
cord-287093-9mertwj7	76	18	alphavirus	alphavirus	NNP
cord-287093-9mertwj7	76	19	and	and	CC
cord-287093-9mertwj7	76	20	nodavirus	nodavirus	NN
cord-287093-9mertwj7	76	21	replication	replication	NN
cord-287093-9mertwj7	76	22	[	[	-LRB-
cord-287093-9mertwj7	76	23	17	17	CD
cord-287093-9mertwj7	76	24	,	,	,
cord-287093-9mertwj7	76	25	18	18	CD
cord-287093-9mertwj7	76	26	]	]	-RRB-
cord-287093-9mertwj7	76	27	and	and	CC
cord-287093-9mertwj7	76	28	both	both	DT
cord-287093-9mertwj7	76	29	FHV	FHV	NNP
cord-287093-9mertwj7	76	30	and	and	CC
cord-287093-9mertwj7	76	31	SFV	SFV	NNP
cord-287093-9mertwj7	76	32	appear	appear	VBP
cord-287093-9mertwj7	76	33	to	to	TO
cord-287093-9mertwj7	76	34	upregulate	upregulate	VB
cord-287093-9mertwj7	76	35	phosphatidylcholine	phosphatidylcholine	NN
cord-287093-9mertwj7	76	36	synthesis	synthesis	NN
cord-287093-9mertwj7	76	37	[	[	-LRB-
cord-287093-9mertwj7	76	38	18	18	CD
cord-287093-9mertwj7	76	39	]	]	-RRB-
cord-287093-9mertwj7	76	40	.	.	.
cord-287093-9mertwj7	77	1	Similarly	similarly	RB
cord-287093-9mertwj7	77	2	,	,	,
cord-287093-9mertwj7	77	3	hepatitis	hepatitis	NN
cord-287093-9mertwj7	77	4	C	c	NN
cord-287093-9mertwj7	77	5	virus	virus	NN
cord-287093-9mertwj7	77	6	(	(	-LRB-
cord-287093-9mertwj7	77	7	HCV	HCV	NNP
cord-287093-9mertwj7	77	8	)	)	-RRB-
cord-287093-9mertwj7	77	9	replication	replication	NN
cord-287093-9mertwj7	77	10	requires	require	VBZ
cord-287093-9mertwj7	77	11	fatty	fatty	JJ
cord-287093-9mertwj7	77	12	acid	acid	NN
cord-287093-9mertwj7	77	13	synthesis	synthesis	NN
cord-287093-9mertwj7	77	14	and	and	CC
cord-287093-9mertwj7	77	15	geranylgeranylation	geranylgeranylation	NN
cord-287093-9mertwj7	77	16	[	[	-LRB-
cord-287093-9mertwj7	77	17	19	19	CD
cord-287093-9mertwj7	77	18	]	]	-RRB-
cord-287093-9mertwj7	77	19	and	and	CC
cord-287093-9mertwj7	77	20	cerulenin	cerulenin	NNP
cord-287093-9mertwj7	77	21	also	also	RB
cord-287093-9mertwj7	77	22	inhibits	inhibit	VBZ
cord-287093-9mertwj7	77	23	poliovirus	poliovirus	NN
cord-287093-9mertwj7	77	24	(	(	-LRB-
cord-287093-9mertwj7	77	25	PV	pv	NN
cord-287093-9mertwj7	77	26	)	)	-RRB-
cord-287093-9mertwj7	77	27	viral	viral	JJ
cord-287093-9mertwj7	77	28	RNA	RNA	NNP
cord-287093-9mertwj7	77	29	synthesis	synthesis	NN
cord-287093-9mertwj7	77	30	[	[	-LRB-
cord-287093-9mertwj7	77	31	20	20	CD
cord-287093-9mertwj7	77	32	]	]	-RRB-
cord-287093-9mertwj7	77	33	and	and	CC
cord-287093-9mertwj7	77	34	coxsackievirus	coxsackievirus	NNP
cord-287093-9mertwj7	77	35	B3	B3	NNP
cord-287093-9mertwj7	77	36	replication	replication	NN
cord-287093-9mertwj7	77	37	[	[	-LRB-
cord-287093-9mertwj7	77	38	21	21	CD
cord-287093-9mertwj7	77	39	]	]	-RRB-
cord-287093-9mertwj7	77	40	.	.	.
cord-287093-9mertwj7	78	1	This	this	DT
cord-287093-9mertwj7	78	2	suggests	suggest	VBZ
cord-287093-9mertwj7	78	3	that	that	IN
cord-287093-9mertwj7	78	4	lipid	lipid	NN
cord-287093-9mertwj7	78	5	synthesis	synthesis	NN
cord-287093-9mertwj7	78	6	is	be	VBZ
cord-287093-9mertwj7	78	7	required	require	VBN
cord-287093-9mertwj7	78	8	for	for	IN
cord-287093-9mertwj7	78	9	efficient	efficient	JJ
cord-287093-9mertwj7	78	10	replication	replication	NN
cord-287093-9mertwj7	78	11	of	of	IN
cord-287093-9mertwj7	78	12	many	many	JJ
cord-287093-9mertwj7	78	13	different	different	JJ
cord-287093-9mertwj7	78	14	(	(	-LRB-
cord-287093-9mertwj7	78	15	+	+	CC
cord-287093-9mertwj7	78	16	)	)	-RRB-
cord-287093-9mertwj7	78	17	strand	strand	NN
cord-287093-9mertwj7	78	18	RNA	RNA	NNP
cord-287093-9mertwj7	78	19	viruses	virus	NNS
cord-287093-9mertwj7	78	20	.	.	.
cord-287093-9mertwj7	79	1	Viral	viral	JJ
cord-287093-9mertwj7	79	2	proteins	protein	NNS
cord-287093-9mertwj7	79	3	that	that	WDT
cord-287093-9mertwj7	79	4	generate	generate	VBP
cord-287093-9mertwj7	79	5	DMVs	dmv	NNS
cord-287093-9mertwj7	79	6	are	be	VBP
cord-287093-9mertwj7	79	7	beginning	begin	VBG
cord-287093-9mertwj7	79	8	to	to	TO
cord-287093-9mertwj7	79	9	be	be	VB
cord-287093-9mertwj7	79	10	identified	identify	VBN
cord-287093-9mertwj7	79	11	.	.	.
cord-287093-9mertwj7	80	1	When	when	WRB
cord-287093-9mertwj7	80	2	expressed	express	VBN
cord-287093-9mertwj7	80	3	separately	separately	RB
cord-287093-9mertwj7	80	4	the	the	DT
cord-287093-9mertwj7	80	5	picornavirus	picornavirus	NNP
cord-287093-9mertwj7	80	6	2BC	2BC	NNP
cord-287093-9mertwj7	80	7	,	,	,
cord-287093-9mertwj7	80	8	2C	2C	NNP
cord-287093-9mertwj7	80	9	and	and	CC
cord-287093-9mertwj7	80	10	3A	3a	NN
cord-287093-9mertwj7	80	11	proteins	protein	NNS
cord-287093-9mertwj7	80	12	generate	generate	VBP
cord-287093-9mertwj7	80	13	ER	ER	NNP
cord-287093-9mertwj7	80	14	vesicles	vesicle	NNS
cord-287093-9mertwj7	80	15	and	and	CC
cord-287093-9mertwj7	80	16	tubules	tubule	NNS
cord-287093-9mertwj7	80	17	but	but	CC
cord-287093-9mertwj7	80	18	these	these	DT
cord-287093-9mertwj7	80	19	differ	differ	VBP
cord-287093-9mertwj7	80	20	from	from	IN
cord-287093-9mertwj7	80	21	the	the	DT
cord-287093-9mertwj7	80	22	vesicles	vesicle	NNS
cord-287093-9mertwj7	80	23	produced	produce	VBN
cord-287093-9mertwj7	80	24	during	during	IN
cord-287093-9mertwj7	80	25	infection	infection	NN
cord-287093-9mertwj7	80	26	.	.	.
cord-287093-9mertwj7	81	1	For	for	IN
cord-287093-9mertwj7	81	2	PV	pv	NN
cord-287093-9mertwj7	81	3	,	,	,
cord-287093-9mertwj7	81	4	coexpression	coexpression	NN
cord-287093-9mertwj7	81	5	of	of	IN
cord-287093-9mertwj7	81	6	2BC	2BC	NNP
cord-287093-9mertwj7	81	7	and	and	CC
cord-287093-9mertwj7	81	8	3A	3A	NNP
cord-287093-9mertwj7	81	9	can	can	MD
cord-287093-9mertwj7	81	10	generate	generate	VB
cord-287093-9mertwj7	81	11	DMVs	dmv	NNS
cord-287093-9mertwj7	81	12	similar	similar	JJ
cord-287093-9mertwj7	81	13	to	to	IN
cord-287093-9mertwj7	81	14	those	those	DT
cord-287093-9mertwj7	81	15	seen	see	VBN
cord-287093-9mertwj7	81	16	in	in	IN
cord-287093-9mertwj7	81	17	infected	infected	JJ
cord-287093-9mertwj7	81	18	cells	cell	NNS
cord-287093-9mertwj7	81	19	[	[	-LRB-
cord-287093-9mertwj7	81	20	16	16	CD
cord-287093-9mertwj7	81	21	]	]	-RRB-
cord-287093-9mertwj7	81	22	.	.	.
cord-287093-9mertwj7	82	1	The	the	DT
cord-287093-9mertwj7	82	2	arterivirus	arterivirus	NN
cord-287093-9mertwj7	82	3	nsp3	nsp3	NNS
cord-287093-9mertwj7	82	4	and	and	CC
cord-287093-9mertwj7	82	5	the	the	DT
cord-287093-9mertwj7	82	6	coronavirus	coronavirus	NN
cord-287093-9mertwj7	82	7	equivalent	equivalent	NN
cord-287093-9mertwj7	82	8	nsp4	nsp4	NNS
cord-287093-9mertwj7	82	9	proteins	protein	NNS
cord-287093-9mertwj7	82	10	are	be	VBP
cord-287093-9mertwj7	82	11	multispanning	multispanne	VBG
cord-287093-9mertwj7	82	12	ER	ER	NNP
cord-287093-9mertwj7	82	13	membrane	membrane	NN
cord-287093-9mertwj7	82	14	proteins	protein	NNS
cord-287093-9mertwj7	82	15	.	.	.
cord-287093-9mertwj7	83	1	Coexpression	coexpression	NN
cord-287093-9mertwj7	83	2	of	of	IN
cord-287093-9mertwj7	83	3	equine	equine	JJ
cord-287093-9mertwj7	83	4	arterivirus	arterivirus	NNP
cord-287093-9mertwj7	83	5	nsp2	nsp2	NNP
cord-287093-9mertwj7	83	6	and	and	CC
cord-287093-9mertwj7	83	7	3	3	CD
cord-287093-9mertwj7	83	8	[	[	-LRB-
cord-287093-9mertwj7	83	9	22	22	CD
cord-287093-9mertwj7	83	10	]	]	-RRB-
cord-287093-9mertwj7	83	11	can	can	MD
cord-287093-9mertwj7	83	12	generate	generate	VB
cord-287093-9mertwj7	83	13	DMVs	dmv	NNS
cord-287093-9mertwj7	83	14	from	from	IN
cord-287093-9mertwj7	83	15	the	the	DT
cord-287093-9mertwj7	83	16	ER	ER	NNP
cord-287093-9mertwj7	83	17	,	,	,
cord-287093-9mertwj7	83	18	and	and	CC
cord-287093-9mertwj7	83	19	protein	protein	NN
cord-287093-9mertwj7	83	20	interactions	interaction	NNS
cord-287093-9mertwj7	83	21	involving	involve	VBG
cord-287093-9mertwj7	83	22	cysteine	cysteine	NN
cord-287093-9mertwj7	83	23	residues	residue	NNS
cord-287093-9mertwj7	83	24	in	in	IN
cord-287093-9mertwj7	83	25	the	the	DT
cord-287093-9mertwj7	83	26	first	first	JJ
cord-287093-9mertwj7	83	27	loop	loop	NN
cord-287093-9mertwj7	83	28	domain	domain	NN
cord-287093-9mertwj7	83	29	are	be	VBP
cord-287093-9mertwj7	83	30	required	require	VBN
cord-287093-9mertwj7	83	31	for	for	IN
cord-287093-9mertwj7	83	32	generating	generate	VBG
cord-287093-9mertwj7	83	33	correct	correct	JJ
cord-287093-9mertwj7	83	34	curvature	curvature	NN
cord-287093-9mertwj7	83	35	[	[	-LRB-
cord-287093-9mertwj7	83	36	23	23	CD
cord-287093-9mertwj7	83	37	]	]	-RRB-
cord-287093-9mertwj7	83	38	.	.	.
cord-287093-9mertwj7	84	1	DMV	DMV	NNP
cord-287093-9mertwj7	84	2	formation	formation	NN
cord-287093-9mertwj7	84	3	may	may	MD
cord-287093-9mertwj7	84	4	also	also	RB
cord-287093-9mertwj7	84	5	require	require	VB
cord-287093-9mertwj7	84	6	host	host	NN
cord-287093-9mertwj7	84	7	proteins	protein	NNS
cord-287093-9mertwj7	84	8	that	that	WDT
cord-287093-9mertwj7	84	9	regulate	regulate	VBP
cord-287093-9mertwj7	84	10	the	the	DT
cord-287093-9mertwj7	84	11	formation	formation	NN
cord-287093-9mertwj7	84	12	of	of	IN
cord-287093-9mertwj7	84	13	vesicles	vesicle	NNS
cord-287093-9mertwj7	84	14	within	within	IN
cord-287093-9mertwj7	84	15	the	the	DT
cord-287093-9mertwj7	84	16	ER	ER	NNP
cord-287093-9mertwj7	84	17	and	and	CC
cord-287093-9mertwj7	84	18	Golgi	Golgi	NNP
cord-287093-9mertwj7	84	19	.	.	.
cord-287093-9mertwj7	85	1	Inhibition	inhibition	NN
cord-287093-9mertwj7	85	2	of	of	IN
cord-287093-9mertwj7	85	3	Sar1	Sar1	NNP
cord-287093-9mertwj7	85	4	and	and	CC
cord-287093-9mertwj7	85	5	Arf1	Arf1	NNP
cord-287093-9mertwj7	85	6	GTPases	GTPases	NNP
cord-287093-9mertwj7	85	7	inhibits	inhibit	VBZ
cord-287093-9mertwj7	85	8	RNA	RNA	NNP
cord-287093-9mertwj7	85	9	replication	replication	NN
cord-287093-9mertwj7	85	10	,	,	,
cord-287093-9mertwj7	85	11	and	and	CC
cord-287093-9mertwj7	85	12	inhibition	inhibition	NN
cord-287093-9mertwj7	85	13	of	of	IN
cord-287093-9mertwj7	85	14	the	the	DT
cord-287093-9mertwj7	85	15	Arf	Arf	NNP
cord-287093-9mertwj7	85	16	GTP	GTP	NNP
cord-287093-9mertwj7	85	17	exchange	exchange	NN
cord-287093-9mertwj7	85	18	factor	factor	NN
cord-287093-9mertwj7	85	19	,	,	,
cord-287093-9mertwj7	85	20	GBF1	GBF1	NNP
cord-287093-9mertwj7	85	21	,	,	,
cord-287093-9mertwj7	85	22	by	by	IN
cord-287093-9mertwj7	85	23	brefeldin	brefeldin	NNP
cord-287093-9mertwj7	86	1	A	a	DT
cord-287093-9mertwj7	86	2	reduces	reduce	VBZ
cord-287093-9mertwj7	86	3	the	the	DT
cord-287093-9mertwj7	86	4	number	number	NN
cord-287093-9mertwj7	86	5	of	of	IN
cord-287093-9mertwj7	86	6	DMVs	dmv	NNS
cord-287093-9mertwj7	86	7	in	in	IN
cord-287093-9mertwj7	86	8	infected	infected	JJ
cord-287093-9mertwj7	86	9	cells	cell	NNS
cord-287093-9mertwj7	86	10	[	[	-LRB-
cord-287093-9mertwj7	86	11	24	24	CD
cord-287093-9mertwj7	86	12	]	]	-RRB-
cord-287093-9mertwj7	86	13	.	.	.
cord-287093-9mertwj7	87	1	The	the	DT
cord-287093-9mertwj7	87	2	downstream	downstream	JJ
cord-287093-9mertwj7	87	3	effector	effector	NN
cord-287093-9mertwj7	87	4	of	of	IN
cord-287093-9mertwj7	87	5	Arf1	Arf1	NNP
cord-287093-9mertwj7	87	6	required	require	VBN
cord-287093-9mertwj7	87	7	by	by	IN
cord-287093-9mertwj7	87	8	coronaviruses	coronaviruse	NNS
cord-287093-9mertwj7	87	9	remains	remain	VBZ
cord-287093-9mertwj7	87	10	unknown	unknown	JJ
cord-287093-9mertwj7	87	11	but	but	CC
cord-287093-9mertwj7	87	12	may	may	MD
cord-287093-9mertwj7	87	13	be	be	VB
cord-287093-9mertwj7	87	14	the	the	DT
cord-287093-9mertwj7	87	15	phosphatidylinositol-4-kinase	phosphatidylinositol-4-kinase	NN
cord-287093-9mertwj7	87	16	-	-	HYPH
cord-287093-9mertwj7	87	17	IIIb	iiib	NN
cord-287093-9mertwj7	87	18	(	(	-LRB-
cord-287093-9mertwj7	87	19	PI4KIIIb	PI4KIIIb	NNP
cord-287093-9mertwj7	87	20	)	)	-RRB-
cord-287093-9mertwj7	87	21	shown	show	VBN
cord-287093-9mertwj7	87	22	to	to	TO
cord-287093-9mertwj7	87	23	play	play	VB
cord-287093-9mertwj7	87	24	a	a	DT
cord-287093-9mertwj7	87	25	role	role	NN
cord-287093-9mertwj7	87	26	in	in	IN
cord-287093-9mertwj7	87	27	picornavirus	picornavirus	NNP
cord-287093-9mertwj7	87	28	and	and	CC
cord-287093-9mertwj7	87	29	HCV	HCV	NNP
cord-287093-9mertwj7	87	30	replication	replication	NN
cord-287093-9mertwj7	87	31	(	(	-LRB-
cord-287093-9mertwj7	87	32	see	see	VB
cord-287093-9mertwj7	87	33	below	below	RB
cord-287093-9mertwj7	87	34	)	)	-RRB-
cord-287093-9mertwj7	87	35	.	.	.
cord-287093-9mertwj7	88	1	For	for	IN
cord-287093-9mertwj7	88	2	enteroviruses	enterovirus	NNS
cord-287093-9mertwj7	88	3	such	such	JJ
cord-287093-9mertwj7	88	4	as	as	IN
cord-287093-9mertwj7	88	5	PV	PV	NNP
cord-287093-9mertwj7	88	6	and	and	CC
cord-287093-9mertwj7	88	7	coxsackieviruses	coxsackievirus	NNS
cord-287093-9mertwj7	88	8	,	,	,
cord-287093-9mertwj7	88	9	the	the	DT
cord-287093-9mertwj7	88	10	nonstructural	nonstructural	JJ
cord-287093-9mertwj7	88	11	protein	protein	NN
cord-287093-9mertwj7	88	12	3A	3A	NNP
cord-287093-9mertwj7	88	13	may	may	MD
cord-287093-9mertwj7	88	14	play	play	VB
cord-287093-9mertwj7	88	15	a	a	DT
cord-287093-9mertwj7	88	16	crucial	crucial	JJ
cord-287093-9mertwj7	88	17	role	role	NN
cord-287093-9mertwj7	88	18	in	in	IN
cord-287093-9mertwj7	88	19	the	the	DT
cord-287093-9mertwj7	88	20	recruitment	recruitment	NN
cord-287093-9mertwj7	88	21	of	of	IN
cord-287093-9mertwj7	88	22	the	the	DT
cord-287093-9mertwj7	88	23	RdRp	RdRp	NNP
cord-287093-9mertwj7	88	24	,	,	,
cord-287093-9mertwj7	88	25	3D	3d	JJ
cord-287093-9mertwj7	88	26	pol	pol	NN
cord-287093-9mertwj7	88	27	,	,	,
cord-287093-9mertwj7	88	28	to	to	IN
cord-287093-9mertwj7	88	29	the	the	DT
cord-287093-9mertwj7	88	30	cytoplasmic	cytoplasmic	JJ
cord-287093-9mertwj7	88	31	face	face	NN
cord-287093-9mertwj7	88	32	of	of	IN
cord-287093-9mertwj7	88	33	membrane	membrane	NN
cord-287093-9mertwj7	88	34	-	-	HYPH
cord-287093-9mertwj7	88	35	bound	bind	VBN
cord-287093-9mertwj7	88	36	organelles	organelle	NNS
cord-287093-9mertwj7	88	37	by	by	IN
cord-287093-9mertwj7	88	38	increasing	increase	VBG
cord-287093-9mertwj7	88	39	the	the	DT
cord-287093-9mertwj7	88	40	recruitment	recruitment	NN
cord-287093-9mertwj7	88	41	of	of	IN
cord-287093-9mertwj7	88	42	PI4KIIIb	PI4KIIIb	NNP
cord-287093-9mertwj7	88	43	[	[	-LRB-
cord-287093-9mertwj7	88	44	25	25	CD
cord-287093-9mertwj7	88	45	]	]	-RRB-
cord-287093-9mertwj7	88	46	.	.	.
cord-287093-9mertwj7	89	1	The	the	DT
cord-287093-9mertwj7	89	2	mechanism	mechanism	NN
cord-287093-9mertwj7	89	3	hinges	hinge	VBZ
cord-287093-9mertwj7	89	4	on	on	IN
cord-287093-9mertwj7	89	5	the	the	DT
cord-287093-9mertwj7	89	6	ability	ability	NN
cord-287093-9mertwj7	89	7	of	of	IN
cord-287093-9mertwj7	89	8	the	the	DT
cord-287093-9mertwj7	89	9	enterovirus	enterovirus	NN
cord-287093-9mertwj7	89	10	3A	3A	NNP
cord-287093-9mertwj7	89	11	protein	protein	NN
cord-287093-9mertwj7	89	12	to	to	TO
cord-287093-9mertwj7	89	13	modulate	modulate	VB
cord-287093-9mertwj7	89	14	the	the	DT
cord-287093-9mertwj7	89	15	activity	activity	NN
cord-287093-9mertwj7	89	16	of	of	IN
cord-287093-9mertwj7	89	17	the	the	DT
cord-287093-9mertwj7	89	18	Arf1	Arf1	NNP
cord-287093-9mertwj7	89	19	GTPase	GTPase	NNP
cord-287093-9mertwj7	89	20	and	and	CC
cord-287093-9mertwj7	89	21	its	-PRON-	PRP$
cord-287093-9mertwj7	89	22	guanine	guanine	NN
cord-287093-9mertwj7	89	23	nucleotide	nucleotide	JJ
cord-287093-9mertwj7	89	24	exchange	exchange	NN
cord-287093-9mertwj7	89	25	factor	factor	NN
cord-287093-9mertwj7	89	26	GBF1	GBF1	NNP
cord-287093-9mertwj7	89	27	.	.	.
cord-287093-9mertwj7	90	1	Arf1	Arf1	NNP
cord-287093-9mertwj7	90	2	and	and	CC
cord-287093-9mertwj7	90	3	GBF1	GBF1	NNP
cord-287093-9mertwj7	90	4	play	play	VB
cord-287093-9mertwj7	90	5	a	a	DT
cord-287093-9mertwj7	90	6	central	central	JJ
cord-287093-9mertwj7	90	7	role	role	NN
cord-287093-9mertwj7	90	8	in	in	IN
cord-287093-9mertwj7	90	9	regulating	regulate	VBG
cord-287093-9mertwj7	90	10	membrane	membrane	NN
cord-287093-9mertwj7	90	11	traffic	traffic	NN
cord-287093-9mertwj7	90	12	between	between	IN
cord-287093-9mertwj7	90	13	the	the	DT
cord-287093-9mertwj7	90	14	ER	ER	NNP
cord-287093-9mertwj7	90	15	and	and	CC
cord-287093-9mertwj7	90	16	Golgi	Golgi	NNP
cord-287093-9mertwj7	90	17	.	.	.
cord-287093-9mertwj7	91	1	Activation	activation	NN
cord-287093-9mertwj7	91	2	of	of	IN
cord-287093-9mertwj7	91	3	Arf1	Arf1	NNP
cord-287093-9mertwj7	91	4	by	by	IN
cord-287093-9mertwj7	91	5	GBF1	GBF1	NNP
cord-287093-9mertwj7	91	6	catalyses	catalyse	VBZ
cord-287093-9mertwj7	91	7	recruitment	recruitment	NN
cord-287093-9mertwj7	91	8	of	of	IN
cord-287093-9mertwj7	91	9	COP1	COP1	NNP
cord-287093-9mertwj7	91	10	proteins	protein	NNS
cord-287093-9mertwj7	91	11	to	to	IN
cord-287093-9mertwj7	91	12	the	the	DT
cord-287093-9mertwj7	91	13	Golgi	Golgi	NNP
cord-287093-9mertwj7	91	14	to	to	TO
cord-287093-9mertwj7	91	15	facilitate	facilitate	VB
cord-287093-9mertwj7	91	16	formation	formation	NN
cord-287093-9mertwj7	91	17	of	of	IN
cord-287093-9mertwj7	91	18	the	the	DT
cord-287093-9mertwj7	91	19	COP1-coated	cop1-coated	JJ
cord-287093-9mertwj7	91	20	vesicles	vesicle	NNS
cord-287093-9mertwj7	91	21	that	that	WDT
cord-287093-9mertwj7	91	22	carry	carry	VBP
cord-287093-9mertwj7	91	23	proteins	protein	NNS
cord-287093-9mertwj7	91	24	from	from	IN
cord-287093-9mertwj7	91	25	the	the	DT
cord-287093-9mertwj7	91	26	Golgi	Golgi	NNP
cord-287093-9mertwj7	91	27	to	to	IN
cord-287093-9mertwj7	91	28	the	the	DT
cord-287093-9mertwj7	91	29	ER	er	NN
cord-287093-9mertwj7	91	30	.	.	.
cord-287093-9mertwj7	92	1	Binding	bind	VBG
cord-287093-9mertwj7	92	2	of	of	IN
cord-287093-9mertwj7	92	3	enterovirus	enterovirus	NN
cord-287093-9mertwj7	92	4	3A	3a	NN
cord-287093-9mertwj7	92	5	protein	protein	NN
cord-287093-9mertwj7	92	6	to	to	IN
cord-287093-9mertwj7	92	7	GBF1	GBF1	NNP
cord-287093-9mertwj7	92	8	activates	activate	VBZ
cord-287093-9mertwj7	92	9	Arf1	Arf1	NNP
cord-287093-9mertwj7	92	10	and	and	CC
cord-287093-9mertwj7	92	11	increases	increase	VBZ
cord-287093-9mertwj7	92	12	recruitment	recruitment	NN
cord-287093-9mertwj7	92	13	of	of	IN
cord-287093-9mertwj7	92	14	an	an	DT
cord-287093-9mertwj7	92	15	alternative	alternative	JJ
cord-287093-9mertwj7	92	16	Arf1	Arf1	NNP
cord-287093-9mertwj7	92	17	effector	effector	NN
cord-287093-9mertwj7	92	18	protein	protein	NN
cord-287093-9mertwj7	92	19	,	,	,
cord-287093-9mertwj7	92	20	PI4KIIIb	PI4KIIIb	NNP
cord-287093-9mertwj7	92	21	,	,	,
cord-287093-9mertwj7	92	22	to	to	IN
cord-287093-9mertwj7	92	23	membranes	membrane	NNS
cord-287093-9mertwj7	92	24	[	[	-LRB-
cord-287093-9mertwj7	92	25	24	24	CD
cord-287093-9mertwj7	92	26	]	]	-RRB-
cord-287093-9mertwj7	92	27	.	.	.
cord-287093-9mertwj7	93	1	Since	since	IN
cord-287093-9mertwj7	93	2	3D	3d	JJ
cord-287093-9mertwj7	93	3	pol	pol	NN
cord-287093-9mertwj7	93	4	binds	bind	VBZ
cord-287093-9mertwj7	93	5	to	to	IN
cord-287093-9mertwj7	93	6	phosphatidylinositol-4-phosphate	phosphatidylinositol-4-phosphate	NNP
cord-287093-9mertwj7	93	7	(	(	-LRB-
cord-287093-9mertwj7	93	8	PI4-P	PI4-P	NNP
cord-287093-9mertwj7	93	9	)	)	-RRB-
cord-287093-9mertwj7	93	10	,	,	,
cord-287093-9mertwj7	93	11	the	the	DT
cord-287093-9mertwj7	93	12	localised	localised	JJ
cord-287093-9mertwj7	93	13	production	production	NN
cord-287093-9mertwj7	93	14	of	of	IN
cord-287093-9mertwj7	93	15	PI4-P	PI4-P	NNP
cord-287093-9mertwj7	93	16	increases	increase	VBZ
cord-287093-9mertwj7	93	17	recruitment	recruitment	NN
cord-287093-9mertwj7	93	18	of	of	IN
cord-287093-9mertwj7	93	19	the	the	DT
cord-287093-9mertwj7	93	20	3D	3d	JJ
cord-287093-9mertwj7	93	21	pol	pol	NN
cord-287093-9mertwj7	93	22	at	at	IN
cord-287093-9mertwj7	93	23	the	the	DT
cord-287093-9mertwj7	93	24	expense	expense	NN
cord-287093-9mertwj7	93	25	of	of	IN
cord-287093-9mertwj7	93	26	COP1	COP1	NNP
cord-287093-9mertwj7	93	27	.	.	.
cord-287093-9mertwj7	94	1	This	this	DT
cord-287093-9mertwj7	94	2	results	result	VBZ
cord-287093-9mertwj7	94	3	in	in	IN
cord-287093-9mertwj7	94	4	disassembly	disassembly	NN
cord-287093-9mertwj7	94	5	of	of	IN
cord-287093-9mertwj7	94	6	the	the	DT
cord-287093-9mertwj7	94	7	Golgi	Golgi	NNP
cord-287093-9mertwj7	94	8	providing	provide	VBG
cord-287093-9mertwj7	94	9	membrane	membrane	NN
cord-287093-9mertwj7	94	10	vesicles	vesicle	NNS
cord-287093-9mertwj7	94	11	enriched	enrich	VBN
cord-287093-9mertwj7	94	12	in	in	IN
cord-287093-9mertwj7	94	13	PI4-P	PI4-P	NNP
cord-287093-9mertwj7	94	14	for	for	IN
cord-287093-9mertwj7	94	15	replication	replication	NN
cord-287093-9mertwj7	94	16	.	.	.
cord-287093-9mertwj7	95	1	This	this	DT
cord-287093-9mertwj7	95	2	role	role	NN
cord-287093-9mertwj7	95	3	for	for	IN
cord-287093-9mertwj7	95	4	3A	3A	NNP
cord-287093-9mertwj7	95	5	may	may	MD
cord-287093-9mertwj7	95	6	not	not	RB
cord-287093-9mertwj7	95	7	hold	hold	VB
cord-287093-9mertwj7	95	8	for	for	IN
cord-287093-9mertwj7	95	9	other	other	JJ
cord-287093-9mertwj7	95	10	picornaviruses	picornavirus	NNS
cord-287093-9mertwj7	95	11	where	where	WRB
cord-287093-9mertwj7	95	12	replication	replication	NN
cord-287093-9mertwj7	95	13	is	be	VBZ
cord-287093-9mertwj7	95	14	not	not	RB
cord-287093-9mertwj7	95	15	dependent	dependent	JJ
cord-287093-9mertwj7	95	16	on	on	IN
cord-287093-9mertwj7	95	17	an	an	DT
cord-287093-9mertwj7	95	18	active	active	JJ
cord-287093-9mertwj7	95	19	GBF1	GBF1	NNP
cord-287093-9mertwj7	95	20	,	,	,
cord-287093-9mertwj7	95	21	and	and	CC
cord-287093-9mertwj7	95	22	for	for	IN
cord-287093-9mertwj7	95	23	picornaviruses	picornavirus	NNS
cord-287093-9mertwj7	95	24	that	that	WDT
cord-287093-9mertwj7	95	25	express	express	VBP
cord-287093-9mertwj7	95	26	3A	3A	NNP
cord-287093-9mertwj7	95	27	proteins	protein	NNS
cord-287093-9mertwj7	95	28	unable	unable	JJ
cord-287093-9mertwj7	95	29	to	to	TO
cord-287093-9mertwj7	95	30	disrupt	disrupt	VB
cord-287093-9mertwj7	95	31	ER	ER	NNP
cord-287093-9mertwj7	95	32	to	to	IN
cord-287093-9mertwj7	95	33	Golgi	Golgi	NNP
cord-287093-9mertwj7	95	34	transport	transport	NN
cord-287093-9mertwj7	95	35	[	[	-LRB-
cord-287093-9mertwj7	95	36	26	26	CD
cord-287093-9mertwj7	95	37	]	]	-RRB-
cord-287093-9mertwj7	95	38	[	[	-LRB-
cord-287093-9mertwj7	95	39	27	27	CD
cord-287093-9mertwj7	95	40	]	]	-RRB-
cord-287093-9mertwj7	95	41	[	[	-LRB-
cord-287093-9mertwj7	95	42	28	28	CD
cord-287093-9mertwj7	95	43	]	]	-RRB-
cord-287093-9mertwj7	95	44	[	[	-LRB-
cord-287093-9mertwj7	95	45	29	29	CD
cord-287093-9mertwj7	95	46	]	]	-RRB-
cord-287093-9mertwj7	95	47	.	.	.
cord-287093-9mertwj7	96	1	HCV	HCV	NNP
cord-287093-9mertwj7	96	2	also	also	RB
cord-287093-9mertwj7	96	3	promotes	promote	VBZ
cord-287093-9mertwj7	96	4	recruitment	recruitment	NN
cord-287093-9mertwj7	96	5	of	of	IN
cord-287093-9mertwj7	96	6	PI4	PI4	NNP
cord-287093-9mertwj7	96	7	K	K	NNP
cord-287093-9mertwj7	96	8	to	to	TO
cord-287093-9mertwj7	96	9	replication	replication	VB
cord-287093-9mertwj7	96	10	sites	site	NNS
cord-287093-9mertwj7	96	11	[	[	-LRB-
cord-287093-9mertwj7	96	12	25	25	CD
cord-287093-9mertwj7	96	13	,	,	,
cord-287093-9mertwj7	96	14	30	30	CD
cord-287093-9mertwj7	96	15	]	]	-RRB-
cord-287093-9mertwj7	96	16	.	.	.
cord-287093-9mertwj7	97	1	HCV	HCV	NNP
cord-287093-9mertwj7	97	2	generates	generate	VBZ
cord-287093-9mertwj7	97	3	a	a	DT
cord-287093-9mertwj7	97	4	membranous	membranous	JJ
cord-287093-9mertwj7	97	5	web	web	NN
cord-287093-9mertwj7	97	6	with	with	IN
cord-287093-9mertwj7	97	7	many	many	JJ
cord-287093-9mertwj7	97	8	similarities	similarity	NNS
cord-287093-9mertwj7	97	9	to	to	IN
cord-287093-9mertwj7	97	10	the	the	DT
cord-287093-9mertwj7	97	11	network	network	NN
cord-287093-9mertwj7	97	12	of	of	IN
cord-287093-9mertwj7	97	13	spherical	spherical	JJ
cord-287093-9mertwj7	97	14	vesicles	vesicle	NNS
cord-287093-9mertwj7	97	15	and	and	CC
cord-287093-9mertwj7	97	16	CM	cm	NN
cord-287093-9mertwj7	97	17	produced	produce	VBN
cord-287093-9mertwj7	97	18	by	by	IN
cord-287093-9mertwj7	97	19	DENV	DENV	NNP
cord-287093-9mertwj7	97	20	.	.	.
cord-287093-9mertwj7	98	1	PI4-P	PI4-P	NNP
cord-287093-9mertwj7	99	1	lipids	lipid	NNS
cord-287093-9mertwj7	99	2	are	be	VBP
cord-287093-9mertwj7	99	3	colocalised	colocalise	VBN
cord-287093-9mertwj7	99	4	with	with	IN
cord-287093-9mertwj7	99	5	HCV	HCV	NNP
cord-287093-9mertwj7	99	6	replicase	replicase	NN
cord-287093-9mertwj7	99	7	protein	protein	NN
cord-287093-9mertwj7	99	8	NS5A	NS5A	NNP
cord-287093-9mertwj7	99	9	,	,	,
cord-287093-9mertwj7	99	10	and	and	CC
cord-287093-9mertwj7	99	11	replication	replication	NN
cord-287093-9mertwj7	99	12	is	be	VBZ
cord-287093-9mertwj7	99	13	reduced	reduce	VBN
cord-287093-9mertwj7	99	14	following	follow	VBG
cord-287093-9mertwj7	99	15	PI4KIIIb	PI4KIIIb	NNP
cord-287093-9mertwj7	99	16	knockdown	knockdown	NN
cord-287093-9mertwj7	99	17	or	or	CC
cord-287093-9mertwj7	99	18	overexpression	overexpression	NN
cord-287093-9mertwj7	99	19	of	of	IN
cord-287093-9mertwj7	99	20	the	the	DT
cord-287093-9mertwj7	99	21	Sac1	Sac1	NNP
cord-287093-9mertwj7	99	22	phosphatase	phosphatase	NN
cord-287093-9mertwj7	99	23	that	that	WDT
cord-287093-9mertwj7	99	24	removes	remove	VBZ
cord-287093-9mertwj7	99	25	phosphate	phosphate	NN
cord-287093-9mertwj7	99	26	from	from	IN
cord-287093-9mertwj7	99	27	PI4-P.	PI4-P.	NNP
cord-287093-9mertwj7	100	1	The	the	DT
cord-287093-9mertwj7	100	2	hepatitis	hepatitis	NN
cord-287093-9mertwj7	100	3	NS5A	NS5A	NNP
cord-287093-9mertwj7	100	4	protein	protein	NN
cord-287093-9mertwj7	100	5	also	also	RB
cord-287093-9mertwj7	100	6	binds	bind	VBZ
cord-287093-9mertwj7	100	7	PI4KIIIa	PI4KIIIa	NNP
cord-287093-9mertwj7	100	8	and	and	CC
cord-287093-9mertwj7	100	9	stimulates	stimulate	VBZ
cord-287093-9mertwj7	100	10	enzyme	enzyme	NN
cord-287093-9mertwj7	100	11	activity	activity	NN
cord-287093-9mertwj7	100	12	and	and	CC
cord-287093-9mertwj7	100	13	knockdown	knockdown	NN
cord-287093-9mertwj7	100	14	of	of	IN
cord-287093-9mertwj7	100	15	PI4KIIIa	PI4KIIIa	NNP
cord-287093-9mertwj7	100	16	prevents	prevent	VBZ
cord-287093-9mertwj7	100	17	formation	formation	NN
cord-287093-9mertwj7	100	18	of	of	IN
cord-287093-9mertwj7	100	19	the	the	DT
cord-287093-9mertwj7	100	20	membranous	membranous	JJ
cord-287093-9mertwj7	100	21	web	web	NN
cord-287093-9mertwj7	100	22	associated	associate	VBN
cord-287093-9mertwj7	100	23	with	with	IN
cord-287093-9mertwj7	100	24	virus	virus	NN
cord-287093-9mertwj7	100	25	replication	replication	NN
cord-287093-9mertwj7	100	26	[	[	-LRB-
cord-287093-9mertwj7	100	27	30	30	CD
cord-287093-9mertwj7	100	28	,	,	,
cord-287093-9mertwj7	100	29	31	31	CD
cord-287093-9mertwj7	100	30	]	]	-RRB-
cord-287093-9mertwj7	100	31	.	.	.
cord-287093-9mertwj7	101	1	The	the	DT
cord-287093-9mertwj7	101	2	NS5A	NS5A	NNP
cord-287093-9mertwj7	101	3	protein	protein	NN
cord-287093-9mertwj7	101	4	is	be	VBZ
cord-287093-9mertwj7	101	5	anchored	anchor	VBN
cord-287093-9mertwj7	101	6	to	to	IN
cord-287093-9mertwj7	101	7	the	the	DT
cord-287093-9mertwj7	101	8	cytoplasmic	cytoplasmic	JJ
cord-287093-9mertwj7	101	9	face	face	NN
cord-287093-9mertwj7	101	10	of	of	IN
cord-287093-9mertwj7	101	11	the	the	DT
cord-287093-9mertwj7	101	12	membranous	membranous	JJ
cord-287093-9mertwj7	101	13	web	web	NN
cord-287093-9mertwj7	101	14	and	and	CC
cord-287093-9mertwj7	101	15	recruits	recruit	NNS
cord-287093-9mertwj7	101	16	NS5B	ns5b	CD
cord-287093-9mertwj7	101	17	and	and	CC
cord-287093-9mertwj7	101	18	a	a	DT
cord-287093-9mertwj7	101	19	series	series	NN
cord-287093-9mertwj7	101	20	of	of	IN
cord-287093-9mertwj7	101	21	cellular	cellular	JJ
cord-287093-9mertwj7	101	22	proteins	protein	NNS
cord-287093-9mertwj7	101	23	that	that	WDT
cord-287093-9mertwj7	101	24	regulate	regulate	VBP
cord-287093-9mertwj7	101	25	membrane	membrane	NN
cord-287093-9mertwj7	101	26	vesicle	vesicle	NN
cord-287093-9mertwj7	101	27	formation	formation	NN
cord-287093-9mertwj7	101	28	.	.	.
cord-287093-9mertwj7	102	1	These	these	DT
cord-287093-9mertwj7	102	2	include	include	VBP
cord-287093-9mertwj7	102	3	vesicle	vesicle	NN
cord-287093-9mertwj7	102	4	-	-	HYPH
cord-287093-9mertwj7	102	5	associated	associate	VBN
cord-287093-9mertwj7	102	6	membrane	membrane	NN
cord-287093-9mertwj7	102	7	protein	protein	NN
cord-287093-9mertwj7	102	8	-	-	HYPH
cord-287093-9mertwj7	102	9	associated	associate	VBN
cord-287093-9mertwj7	102	10	proteins	protein	NNS
cord-287093-9mertwj7	102	11	[	[	-LRB-
cord-287093-9mertwj7	102	12	32	32	CD
cord-287093-9mertwj7	102	13	]	]	-RRB-
cord-287093-9mertwj7	102	14	which	which	WDT
cord-287093-9mertwj7	102	15	bind	bind	VBP
cord-287093-9mertwj7	102	16	SNAREs	snare	NNS
cord-287093-9mertwj7	102	17	involved	involve	VBN
cord-287093-9mertwj7	102	18	in	in	IN
cord-287093-9mertwj7	102	19	ER	ER	NNP
cord-287093-9mertwj7	102	20	to	to	IN
cord-287093-9mertwj7	102	21	Golgi	Golgi	NNP
cord-287093-9mertwj7	102	22	transport	transport	NN
cord-287093-9mertwj7	102	23	,	,	,
cord-287093-9mertwj7	102	24	and	and	CC
cord-287093-9mertwj7	102	25	a	a	DT
cord-287093-9mertwj7	102	26	Rab1-GAP	rab1-gap	NN
cord-287093-9mertwj7	102	27	protein	protein	NN
cord-287093-9mertwj7	102	28	,	,	,
cord-287093-9mertwj7	102	29	TBC1D20	TBC1D20	NNP
cord-287093-9mertwj7	102	30	.	.	.
cord-287093-9mertwj7	103	1	NS4B	NS4B	NNP
cord-287093-9mertwj7	103	2	can	can	MD
cord-287093-9mertwj7	103	3	recruit	recruit	VB
cord-287093-9mertwj7	103	4	Rab5	Rab5	NNP
cord-287093-9mertwj7	103	5	and	and	CC
cord-287093-9mertwj7	103	6	Rab5	Rab5	NNP
cord-287093-9mertwj7	103	7	effectors	effector	NNS
cord-287093-9mertwj7	104	1	EEA1	EEA1	NNP
cord-287093-9mertwj7	104	2	,	,	,
cord-287093-9mertwj7	104	3	rabaptin	rabaptin	JJS
cord-287093-9mertwj7	104	4	5	5	CD
cord-287093-9mertwj7	104	5	and	and	CC
cord-287093-9mertwj7	104	6	Rab4	rab4	JJ
cord-287093-9mertwj7	104	7	[	[	-LRB-
cord-287093-9mertwj7	104	8	31	31	CD
cord-287093-9mertwj7	104	9	]	]	-RRB-
cord-287093-9mertwj7	104	10	suggesting	suggest	VBG
cord-287093-9mertwj7	104	11	the	the	DT
cord-287093-9mertwj7	104	12	web	web	NN
cord-287093-9mertwj7	104	13	may	may	MD
cord-287093-9mertwj7	104	14	fuse	fuse	VB
cord-287093-9mertwj7	104	15	with	with	IN
cord-287093-9mertwj7	104	16	endosomes	endosome	NNS
cord-287093-9mertwj7	104	17	[	[	-LRB-
cord-287093-9mertwj7	104	18	33	33	CD
cord-287093-9mertwj7	104	19	]	]	-RRB-
cord-287093-9mertwj7	104	20	.	.	.
cord-287093-9mertwj7	105	1	Double	double	JJ
cord-287093-9mertwj7	105	2	-	-	HYPH
cord-287093-9mertwj7	105	3	membraned	membraned	JJ
cord-287093-9mertwj7	105	4	vesicles	vesicle	NNS
cord-287093-9mertwj7	105	5	are	be	VBP
cord-287093-9mertwj7	105	6	usually	usually	RB
cord-287093-9mertwj7	105	7	rare	rare	JJ
cord-287093-9mertwj7	105	8	in	in	IN
cord-287093-9mertwj7	105	9	cells	cell	NNS
cord-287093-9mertwj7	105	10	,	,	,
cord-287093-9mertwj7	105	11	but	but	CC
cord-287093-9mertwj7	105	12	DMVs	dmv	NNS
cord-287093-9mertwj7	105	13	are	be	VBP
cord-287093-9mertwj7	105	14	induced	induce	VBN
cord-287093-9mertwj7	105	15	during	during	IN
cord-287093-9mertwj7	105	16	autophagy	autophagy	NN
cord-287093-9mertwj7	105	17	.	.	.
cord-287093-9mertwj7	106	1	This	this	DT
cord-287093-9mertwj7	106	2	makes	make	VBZ
cord-287093-9mertwj7	106	3	it	-PRON-	PRP
cord-287093-9mertwj7	106	4	possible	possible	JJ
cord-287093-9mertwj7	106	5	that	that	IN
cord-287093-9mertwj7	106	6	autophagosomes	autophagosomes	NNP
cord-287093-9mertwj7	106	7	may	may	MD
cord-287093-9mertwj7	106	8	provide	provide	VB
cord-287093-9mertwj7	106	9	a	a	DT
cord-287093-9mertwj7	106	10	source	source	NN
cord-287093-9mertwj7	106	11	for	for	IN
cord-287093-9mertwj7	106	12	DMVs	dmv	NNS
cord-287093-9mertwj7	106	13	associated	associate	VBN
cord-287093-9mertwj7	106	14	with	with	IN
cord-287093-9mertwj7	106	15	virus	virus	NN
cord-287093-9mertwj7	106	16	replication	replication	NN
cord-287093-9mertwj7	106	17	.	.	.
cord-287093-9mertwj7	107	1	A	a	DT
cord-287093-9mertwj7	107	2	role	role	NN
cord-287093-9mertwj7	107	3	for	for	IN
cord-287093-9mertwj7	107	4	autophagosomes	autophagosome	NNS
cord-287093-9mertwj7	107	5	in	in	IN
cord-287093-9mertwj7	107	6	supporting	support	VBG
cord-287093-9mertwj7	107	7	replication	replication	NN
cord-287093-9mertwj7	107	8	of	of	IN
cord-287093-9mertwj7	107	9	the	the	DT
cord-287093-9mertwj7	107	10	coronavirus	coronavirus	NN
cord-287093-9mertwj7	107	11	mouse	mouse	NN
cord-287093-9mertwj7	107	12	hepatitis	hepatitis	NN
cord-287093-9mertwj7	107	13	virus	virus	NN
cord-287093-9mertwj7	107	14	(	(	-LRB-
cord-287093-9mertwj7	107	15	MHV	MHV	NNP
cord-287093-9mertwj7	107	16	)	)	-RRB-
cord-287093-9mertwj7	107	17	was	be	VBD
cord-287093-9mertwj7	107	18	first	first	RB
cord-287093-9mertwj7	107	19	provided	provide	VBN
cord-287093-9mertwj7	107	20	by	by	IN
cord-287093-9mertwj7	107	21	studies	study	NNS
cord-287093-9mertwj7	107	22	where	where	WRB
cord-287093-9mertwj7	107	23	mouse	mouse	NN
cord-287093-9mertwj7	107	24	embryonic	embryonic	JJ
cord-287093-9mertwj7	107	25	stem	stem	NN
cord-287093-9mertwj7	107	26	cells	cell	NNS
cord-287093-9mertwj7	107	27	lacking	lack	VBG
cord-287093-9mertwj7	107	28	crucial	crucial	JJ
cord-287093-9mertwj7	107	29	autophagy	autophagy	NN
cord-287093-9mertwj7	107	30	protein	protein	NN
cord-287093-9mertwj7	107	31	Atg5	Atg5	NNP
cord-287093-9mertwj7	107	32	showed	show	VBD
cord-287093-9mertwj7	107	33	a	a	DT
cord-287093-9mertwj7	107	34	1000-fold	1000-fold	CD
cord-287093-9mertwj7	107	35	reduction	reduction	NN
cord-287093-9mertwj7	107	36	in	in	IN
cord-287093-9mertwj7	107	37	MHV	MHV	NNP
cord-287093-9mertwj7	107	38	replication	replication	NN
cord-287093-9mertwj7	107	39	and	and	CC
cord-287093-9mertwj7	107	40	reduced	reduce	VBN
cord-287093-9mertwj7	107	41	numbers	number	NNS
cord-287093-9mertwj7	107	42	of	of	IN
cord-287093-9mertwj7	107	43	DMVs	dmv	NNS
cord-287093-9mertwj7	107	44	[	[	-LRB-
cord-287093-9mertwj7	107	45	34	34	CD
cord-287093-9mertwj7	107	46	]	]	-RRB-
cord-287093-9mertwj7	107	47	.	.	.
cord-287093-9mertwj7	108	1	Less	less	RBR
cord-287093-9mertwj7	108	2	clear	clear	RB
cord-287093-9mertwj7	108	3	-	-	HYPH
cord-287093-9mertwj7	108	4	cut	cut	VBN
cord-287093-9mertwj7	108	5	results	result	NNS
cord-287093-9mertwj7	108	6	come	come	VBP
cord-287093-9mertwj7	108	7	from	from	IN
cord-287093-9mertwj7	108	8	studies	study	NNS
cord-287093-9mertwj7	108	9	of	of	IN
cord-287093-9mertwj7	108	10	primary	primary	JJ
cord-287093-9mertwj7	108	11	fibroblasts	fibroblast	NNS
cord-287093-9mertwj7	108	12	or	or	CC
cord-287093-9mertwj7	108	13	macrophages	macrophage	NNS
cord-287093-9mertwj7	108	14	where	where	WRB
cord-287093-9mertwj7	108	15	loss	loss	NN
cord-287093-9mertwj7	108	16	of	of	IN
cord-287093-9mertwj7	108	17	Atg5	Atg5	NNP
cord-287093-9mertwj7	108	18	has	have	VBZ
cord-287093-9mertwj7	108	19	little	little	JJ
cord-287093-9mertwj7	108	20	impact	impact	NN
cord-287093-9mertwj7	108	21	on	on	IN
cord-287093-9mertwj7	108	22	virus	virus	NN
cord-287093-9mertwj7	108	23	replication	replication	NN
cord-287093-9mertwj7	108	24	[	[	-LRB-
cord-287093-9mertwj7	108	25	35	35	CD
cord-287093-9mertwj7	108	26	]	]	-RRB-
cord-287093-9mertwj7	108	27	.	.	.
cord-287093-9mertwj7	109	1	Vesicles	Vesicles	NNP
cord-287093-9mertwj7	109	2	labelled	label	VBN
cord-287093-9mertwj7	109	3	with	with	IN
cord-287093-9mertwj7	109	4	autophagy	autophagy	NN
cord-287093-9mertwj7	109	5	marker	marker	NN
cord-287093-9mertwj7	109	6	LC3	LC3	NNP
cord-287093-9mertwj7	109	7	are	be	VBP
cord-287093-9mertwj7	109	8	,	,	,
cord-287093-9mertwj7	109	9	however	however	RB
cord-287093-9mertwj7	109	10	,	,	,
cord-287093-9mertwj7	109	11	produced	produce	VBN
cord-287093-9mertwj7	109	12	during	during	IN
cord-287093-9mertwj7	109	13	coronavirus	coronavirus	NN
cord-287093-9mertwj7	109	14	infection	infection	NN
cord-287093-9mertwj7	109	15	suggesting	suggest	VBG
cord-287093-9mertwj7	109	16	that	that	IN
cord-287093-9mertwj7	109	17	the	the	DT
cord-287093-9mertwj7	109	18	virus	virus	NN
cord-287093-9mertwj7	109	19	activates	activate	VBZ
cord-287093-9mertwj7	109	20	autophagy	autophagy	NN
cord-287093-9mertwj7	109	21	.	.	.
cord-287093-9mertwj7	110	1	Autophagy	Autophagy	NNP
cord-287093-9mertwj7	110	2	may	may	MD
cord-287093-9mertwj7	110	3	be	be	VB
cord-287093-9mertwj7	110	4	activated	activate	VBN
cord-287093-9mertwj7	110	5	by	by	IN
cord-287093-9mertwj7	110	6	the	the	DT
cord-287093-9mertwj7	110	7	nsp6	nsp6	NN
cord-287093-9mertwj7	110	8	proteins	protein	NNS
cord-287093-9mertwj7	110	9	of	of	IN
cord-287093-9mertwj7	110	10	cornaviruses	cornaviruse	NNS
cord-287093-9mertwj7	110	11	,	,	,
cord-287093-9mertwj7	110	12	or	or	CC
cord-287093-9mertwj7	110	13	in	in	IN
cord-287093-9mertwj7	110	14	the	the	DT
cord-287093-9mertwj7	110	15	case	case	NN
cord-287093-9mertwj7	110	16	of	of	IN
cord-287093-9mertwj7	110	17	the	the	DT
cord-287093-9mertwj7	110	18	arteriviruses	arteriviruse	NNS
cord-287093-9mertwj7	110	19	,	,	,
cord-287093-9mertwj7	110	20	the	the	DT
cord-287093-9mertwj7	110	21	equivalent	equivalent	JJ
cord-287093-9mertwj7	110	22	nsp5	nsp5	NN
cord-287093-9mertwj7	110	23	-	-	HYPH
cord-287093-9mertwj7	110	24	7	7	CD
cord-287093-9mertwj7	110	25	protein	protein	NN
cord-287093-9mertwj7	110	26	.	.	.
cord-287093-9mertwj7	111	1	The	the	DT
cord-287093-9mertwj7	111	2	nsp6	nsp6	NN
cord-287093-9mertwj7	111	3	(	(	-LRB-
cord-287093-9mertwj7	111	4	nsp5	nsp5	NN
cord-287093-9mertwj7	111	5	-	-	HYPH
cord-287093-9mertwj7	111	6	7	7	CD
cord-287093-9mertwj7	111	7	)	)	-RRB-
cord-287093-9mertwj7	111	8	proteins	protein	NNS
cord-287093-9mertwj7	111	9	locate	locate	VBP
cord-287093-9mertwj7	111	10	to	to	IN
cord-287093-9mertwj7	111	11	the	the	DT
cord-287093-9mertwj7	111	12	ER	er	NN
cord-287093-9mertwj7	111	13	where	where	WRB
cord-287093-9mertwj7	111	14	they	-PRON-	PRP
cord-287093-9mertwj7	111	15	generate	generate	VBP
cord-287093-9mertwj7	111	16	small	small	JJ
cord-287093-9mertwj7	111	17	vesicles	vesicle	NNS
cord-287093-9mertwj7	111	18	enriched	enrich	VBN
cord-287093-9mertwj7	111	19	in	in	IN
cord-287093-9mertwj7	111	20	phosphatidylinositol-3-phosphate	phosphatidylinositol-3-phosphate	NNP
cord-287093-9mertwj7	111	21	and	and	CC
cord-287093-9mertwj7	111	22	early	early	JJ
cord-287093-9mertwj7	111	23	autophagy	autophagy	NN
cord-287093-9mertwj7	111	24	marker	marker	NN
cord-287093-9mertwj7	112	1	Atg5	atg5	JJ
cord-287093-9mertwj7	112	2	[	[	-LRB-
cord-287093-9mertwj7	112	3	36	36	CD
cord-287093-9mertwj7	112	4	]	]	-RRB-
cord-287093-9mertwj7	112	5	.	.	.
cord-287093-9mertwj7	113	1	These	these	DT
cord-287093-9mertwj7	113	2	vesicles	vesicle	NNS
cord-287093-9mertwj7	113	3	closely	closely	RB
cord-287093-9mertwj7	113	4	resemble	resemble	VBP
cord-287093-9mertwj7	113	5	cellular	cellular	JJ
cord-287093-9mertwj7	113	6	organelles	organelle	NNS
cord-287093-9mertwj7	113	7	called	call	VBN
cord-287093-9mertwj7	113	8	omegasomes	omegasome	NNS
cord-287093-9mertwj7	113	9	that	that	WDT
cord-287093-9mertwj7	113	10	are	be	VBP
cord-287093-9mertwj7	113	11	formed	form	VBN
cord-287093-9mertwj7	113	12	from	from	IN
cord-287093-9mertwj7	113	13	the	the	DT
cord-287093-9mertwj7	113	14	ER	ER	NNP
cord-287093-9mertwj7	113	15	during	during	IN
cord-287093-9mertwj7	113	16	the	the	DT
cord-287093-9mertwj7	113	17	initial	initial	JJ
cord-287093-9mertwj7	113	18	stages	stage	NNS
cord-287093-9mertwj7	113	19	of	of	IN
cord-287093-9mertwj7	113	20	autophagy	autophagy	NN
cord-287093-9mertwj7	113	21	[	[	-LRB-
cord-287093-9mertwj7	113	22	37	37	CD
cord-287093-9mertwj7	113	23	]	]	-RRB-
cord-287093-9mertwj7	113	24	,	,	,
cord-287093-9mertwj7	113	25	and	and	CC
cord-287093-9mertwj7	113	26	mature	mature	VB
cord-287093-9mertwj7	113	27	into	into	IN
cord-287093-9mertwj7	113	28	autophagosomes	autophagosome	NNS
cord-287093-9mertwj7	113	29	labelled	label	VBN
cord-287093-9mertwj7	113	30	with	with	IN
cord-287093-9mertwj7	113	31	autophagy	autophagy	NN
cord-287093-9mertwj7	113	32	marker	marker	NN
cord-287093-9mertwj7	113	33	Atg8	Atg8	NNP
cord-287093-9mertwj7	113	34	/	/	SYM
cord-287093-9mertwj7	113	35	LC3	lc3	NN
cord-287093-9mertwj7	113	36	.	.	.
cord-287093-9mertwj7	114	1	Autophagy	Autophagy	NNP
cord-287093-9mertwj7	114	2	is	be	VBZ
cord-287093-9mertwj7	114	3	activated	activate	VBN
cord-287093-9mertwj7	114	4	during	during	IN
cord-287093-9mertwj7	114	5	cornavirus	cornavirus	NNP
cord-287093-9mertwj7	114	6	infection	infection	NN
cord-287093-9mertwj7	114	7	but	but	CC
cord-287093-9mertwj7	114	8	this	this	DT
cord-287093-9mertwj7	114	9	does	do	VBZ
cord-287093-9mertwj7	114	10	not	not	RB
cord-287093-9mertwj7	114	11	mean	mean	VB
cord-287093-9mertwj7	114	12	that	that	IN
cord-287093-9mertwj7	114	13	all	all	PDT
cord-287093-9mertwj7	114	14	the	the	DT
cord-287093-9mertwj7	114	15	DMVs	dmv	NNS
cord-287093-9mertwj7	114	16	generated	generate	VBN
cord-287093-9mertwj7	114	17	in	in	IN
cord-287093-9mertwj7	114	18	the	the	DT
cord-287093-9mertwj7	114	19	cytoplasm	cytoplasm	NN
cord-287093-9mertwj7	114	20	are	be	VBP
cord-287093-9mertwj7	114	21	autophagosomes	autophagosome	NNS
cord-287093-9mertwj7	114	22	.	.	.
cord-287093-9mertwj7	115	1	Most	Most	JJS
cord-287093-9mertwj7	115	2	of	of	IN
cord-287093-9mertwj7	115	3	the	the	DT
cord-287093-9mertwj7	115	4	DMVs	dmv	NNS
cord-287093-9mertwj7	115	5	are	be	VBP
cord-287093-9mertwj7	115	6	smaller	small	JJR
cord-287093-9mertwj7	115	7	than	than	IN
cord-287093-9mertwj7	115	8	autophagosomes	autophagosomes	NNP
cord-287093-9mertwj7	115	9	and	and	CC
cord-287093-9mertwj7	115	10	may	may	MD
cord-287093-9mertwj7	115	11	be	be	VB
cord-287093-9mertwj7	115	12	formed	form	VBN
cord-287093-9mertwj7	115	13	from	from	IN
cord-287093-9mertwj7	115	14	invaginations	invagination	NNS
cord-287093-9mertwj7	115	15	into	into	IN
cord-287093-9mertwj7	115	16	the	the	DT
cord-287093-9mertwj7	115	17	ER	ER	NNP
cord-287093-9mertwj7	115	18	(	(	-LRB-
cord-287093-9mertwj7	115	19	Figure	figure	NN
cord-287093-9mertwj7	115	20	1	1	CD
cord-287093-9mertwj7	115	21	)	)	-RRB-
cord-287093-9mertwj7	115	22	.	.	.
cord-287093-9mertwj7	116	1	Vesicles	Vesicles	NNP
cord-287093-9mertwj7	116	2	formed	form	VBN
cord-287093-9mertwj7	116	3	from	from	IN
cord-287093-9mertwj7	116	4	the	the	DT
cord-287093-9mertwj7	116	5	ER	ER	NNP
cord-287093-9mertwj7	116	6	during	during	IN
cord-287093-9mertwj7	116	7	coronavirus	coronavirus	NN
cord-287093-9mertwj7	116	8	infection	infection	NN
cord-287093-9mertwj7	116	9	can	can	MD
cord-287093-9mertwj7	116	10	also	also	RB
cord-287093-9mertwj7	116	11	recruit	recruit	VB
cord-287093-9mertwj7	116	12	a	a	DT
cord-287093-9mertwj7	116	13	non	non	JJ
cord-287093-9mertwj7	116	14	-	-	JJ
cord-287093-9mertwj7	116	15	lipidated	lipidated	JJ
cord-287093-9mertwj7	116	16	autophagy	autophagy	NN
cord-287093-9mertwj7	116	17	marker	marker	NN
cord-287093-9mertwj7	116	18	LC3	LC3	NNP
cord-287093-9mertwj7	116	19	(	(	-LRB-
cord-287093-9mertwj7	116	20	LC3I	LC3I	NNP
cord-287093-9mertwj7	116	21	)	)	-RRB-
cord-287093-9mertwj7	116	22	by	by	IN
cord-287093-9mertwj7	116	23	a	a	DT
cord-287093-9mertwj7	116	24	pathway	pathway	NN
cord-287093-9mertwj7	116	25	,	,	.
cord-287093-9mertwj7	117	1	that	that	DT
cord-287093-9mertwj7	117	2	is	is	RB
cord-287093-9mertwj7	117	3	,	,	,
cord-287093-9mertwj7	117	4	paradoxically	paradoxically	RB
cord-287093-9mertwj7	117	5	,	,	,
cord-287093-9mertwj7	117	6	independent	independent	JJ
cord-287093-9mertwj7	117	7	of	of	IN
cord-287093-9mertwj7	117	8	autophagy	autophagy	NN
cord-287093-9mertwj7	117	9	,	,	,
cord-287093-9mertwj7	117	10	and	and	CC
cord-287093-9mertwj7	117	11	linked	link	VBN
cord-287093-9mertwj7	117	12	to	to	IN
cord-287093-9mertwj7	117	13	the	the	DT
cord-287093-9mertwj7	117	14	export	export	NN
cord-287093-9mertwj7	117	15	of	of	IN
cord-287093-9mertwj7	117	16	ER	ER	NNP
cord-287093-9mertwj7	117	17	chaperones	chaperone	NNS
cord-287093-9mertwj7	117	18	from	from	IN
cord-287093-9mertwj7	117	19	the	the	DT
cord-287093-9mertwj7	117	20	ER	ER	NNP
cord-287093-9mertwj7	117	21	to	to	TO
cord-287093-9mertwj7	117	22	endosomes	endosomes	VB
cord-287093-9mertwj7	117	23	[	[	-LRB-
cord-287093-9mertwj7	117	24	38	38	CD
cord-287093-9mertwj7	117	25	]	]	-RRB-
cord-287093-9mertwj7	117	26	.	.	.
cord-287093-9mertwj7	118	1	Autophagosomes	Autophagosomes	NNP
cord-287093-9mertwj7	118	2	may	may	MD
cord-287093-9mertwj7	118	3	not	not	RB
cord-287093-9mertwj7	118	4	therefore	therefore	RB
cord-287093-9mertwj7	118	5	play	play	VB
cord-287093-9mertwj7	118	6	a	a	DT
cord-287093-9mertwj7	118	7	direct	direct	JJ
cord-287093-9mertwj7	118	8	role	role	NN
cord-287093-9mertwj7	118	9	in	in	IN
cord-287093-9mertwj7	118	10	the	the	DT
cord-287093-9mertwj7	118	11	formation	formation	NN
cord-287093-9mertwj7	118	12	of	of	IN
cord-287093-9mertwj7	118	13	virus	virus	NN
cord-287093-9mertwj7	118	14	-	-	HYPH
cord-287093-9mertwj7	118	15	induced	induce	VBN
cord-287093-9mertwj7	118	16	DMVs	dmv	NNS
cord-287093-9mertwj7	118	17	,	,	,
cord-287093-9mertwj7	118	18	but	but	CC
cord-287093-9mertwj7	118	19	may	may	MD
cord-287093-9mertwj7	118	20	represent	represent	VB
cord-287093-9mertwj7	118	21	a	a	DT
cord-287093-9mertwj7	118	22	defence	defence	NN
cord-287093-9mertwj7	118	23	against	against	IN
cord-287093-9mertwj7	118	24	infection	infection	NN
cord-287093-9mertwj7	118	25	.	.	.
cord-287093-9mertwj7	119	1	Picornaviruses	picornavirus	NNS
cord-287093-9mertwj7	119	2	activate	activate	VBP
cord-287093-9mertwj7	119	3	autophagy	autophagy	NN
cord-287093-9mertwj7	119	4	in	in	IN
cord-287093-9mertwj7	119	5	cell	cell	NN
cord-287093-9mertwj7	119	6	culture	culture	NN
cord-287093-9mertwj7	119	7	models	model	NNS
cord-287093-9mertwj7	119	8	[	[	-LRB-
cord-287093-9mertwj7	119	9	39	39	CD
cord-287093-9mertwj7	119	10	]	]	-RRB-
cord-287093-9mertwj7	119	11	and	and	CC
cord-287093-9mertwj7	119	12	in	in	IN
cord-287093-9mertwj7	119	13	some	some	DT
cord-287093-9mertwj7	119	14	cases	case	NNS
cord-287093-9mertwj7	119	15	inhibition	inhibition	NN
cord-287093-9mertwj7	119	16	of	of	IN
cord-287093-9mertwj7	119	17	autophagy	autophagy	NN
cord-287093-9mertwj7	119	18	reduces	reduce	VBZ
cord-287093-9mertwj7	119	19	replication	replication	NN
cord-287093-9mertwj7	119	20	while	while	IN
cord-287093-9mertwj7	119	21	activation	activation	NN
cord-287093-9mertwj7	119	22	increases	increase	VBZ
cord-287093-9mertwj7	119	23	virus	virus	NN
cord-287093-9mertwj7	119	24	yields	yield	NNS
cord-287093-9mertwj7	119	25	.	.	.
cord-287093-9mertwj7	120	1	The	the	DT
cord-287093-9mertwj7	120	2	autophagosome	autophagosome	JJ
cord-287093-9mertwj7	120	3	marker	marker	NN
cord-287093-9mertwj7	120	4	LC3	lc3	NN
cord-287093-9mertwj7	120	5	colocalises	colocalise	VBZ
cord-287093-9mertwj7	120	6	with	with	IN
cord-287093-9mertwj7	120	7	PV	PV	NNP
cord-287093-9mertwj7	120	8	replicase	replicase	NN
cord-287093-9mertwj7	120	9	proteins	protein	NNS
cord-287093-9mertwj7	120	10	suggesting	suggest	VBG
cord-287093-9mertwj7	120	11	replication	replication	NN
cord-287093-9mertwj7	120	12	on	on	IN
cord-287093-9mertwj7	120	13	autophagosomes	autophagosomes	NNP
cord-287093-9mertwj7	120	14	.	.	.
cord-287093-9mertwj7	121	1	Translocation	translocation	NN
cord-287093-9mertwj7	121	2	of	of	IN
cord-287093-9mertwj7	121	3	LC3	lc3	NN
cord-287093-9mertwj7	121	4	to	to	IN
cord-287093-9mertwj7	121	5	vesicles	vesicle	NNS
cord-287093-9mertwj7	121	6	can	can	MD
cord-287093-9mertwj7	121	7	be	be	VB
cord-287093-9mertwj7	121	8	induced	induce	VBN
cord-287093-9mertwj7	121	9	by	by	IN
cord-287093-9mertwj7	121	10	expression	expression	NN
cord-287093-9mertwj7	121	11	of	of	IN
cord-287093-9mertwj7	121	12	PV	PV	NNP
cord-287093-9mertwj7	121	13	2BC	2BC	NNP
cord-287093-9mertwj7	121	14	alone	alone	RB
cord-287093-9mertwj7	121	15	,	,	,
cord-287093-9mertwj7	121	16	but	but	CC
cord-287093-9mertwj7	121	17	formation	formation	NN
cord-287093-9mertwj7	121	18	of	of	IN
cord-287093-9mertwj7	121	19	DMVs	DMVs	NNPS
cord-287093-9mertwj7	121	20	resembling	resemble	VBG
cord-287093-9mertwj7	121	21	autophagosomes	autophagosomes	NNP
cord-287093-9mertwj7	121	22	requires	require	VBZ
cord-287093-9mertwj7	121	23	coexpression	coexpression	NN
cord-287093-9mertwj7	121	24	of	of	IN
cord-287093-9mertwj7	121	25	2BC	2BC	NNP
cord-287093-9mertwj7	121	26	with	with	IN
cord-287093-9mertwj7	121	27	3A	3A	NNP
cord-287093-9mertwj7	121	28	[	[	-LRB-
cord-287093-9mertwj7	121	29	16	16	CD
cord-287093-9mertwj7	121	30	,	,	,
cord-287093-9mertwj7	121	31	39	39	CD
cord-287093-9mertwj7	121	32	]	]	-RRB-
cord-287093-9mertwj7	121	33	.	.	.
cord-287093-9mertwj7	122	1	As	as	IN
cord-287093-9mertwj7	122	2	with	with	IN
cord-287093-9mertwj7	122	3	the	the	DT
cord-287093-9mertwj7	122	4	coronaviruses	coronaviruse	NNS
cord-287093-9mertwj7	122	5	,	,	,
cord-287093-9mertwj7	122	6	the	the	DT
cord-287093-9mertwj7	122	7	picornavirus	picornavirus	NNP
cord-287093-9mertwj7	122	8	DMVs	DMVs	NNPS
cord-287093-9mertwj7	122	9	are	be	VBP
cord-287093-9mertwj7	122	10	approximately	approximately	RB
cord-287093-9mertwj7	122	11	one	one	CD
cord-287093-9mertwj7	122	12	third	third	NN
cord-287093-9mertwj7	122	13	the	the	DT
cord-287093-9mertwj7	122	14	diameter	diameter	NN
cord-287093-9mertwj7	122	15	of	of	IN
cord-287093-9mertwj7	122	16	cellular	cellular	JJ
cord-287093-9mertwj7	122	17	autophagosomes	autophagosome	NNS
cord-287093-9mertwj7	122	18	making	make	VBG
cord-287093-9mertwj7	122	19	it	-PRON-	PRP
cord-287093-9mertwj7	122	20	difficult	difficult	JJ
cord-287093-9mertwj7	122	21	to	to	TO
cord-287093-9mertwj7	122	22	determine	determine	VB
cord-287093-9mertwj7	122	23	if	if	IN
cord-287093-9mertwj7	122	24	assembly	assembly	NN
cord-287093-9mertwj7	122	25	of	of	IN
cord-287093-9mertwj7	122	26	the	the	DT
cord-287093-9mertwj7	122	27	replicase	replicase	NNP
cord-287093-9mertwj7	122	28	complex	complex	JJ
cord-287093-9mertwj7	122	29	results	result	NNS
cord-287093-9mertwj7	122	30	in	in	IN
cord-287093-9mertwj7	122	31	the	the	DT
cord-287093-9mertwj7	122	32	formation	formation	NN
cord-287093-9mertwj7	122	33	of	of	IN
cord-287093-9mertwj7	122	34	DMVs	DMVs	NNPS
cord-287093-9mertwj7	122	35	directly	directly	RB
cord-287093-9mertwj7	122	36	,	,	,
cord-287093-9mertwj7	122	37	or	or	CC
cord-287093-9mertwj7	122	38	if	if	IN
cord-287093-9mertwj7	122	39	the	the	DT
cord-287093-9mertwj7	122	40	DMVs	dmv	NNS
cord-287093-9mertwj7	122	41	represent	represent	VBP
cord-287093-9mertwj7	122	42	modified	modify	VBN
cord-287093-9mertwj7	122	43	autophagosomes	autophagosome	NNS
cord-287093-9mertwj7	122	44	.	.	.
cord-287093-9mertwj7	123	1	Virus	virus	NN
cord-287093-9mertwj7	123	2	assembly	assembly	NN
cord-287093-9mertwj7	123	3	and	and	CC
cord-287093-9mertwj7	123	4	replication	replication	NN
cord-287093-9mertwj7	123	5	can	can	MD
cord-287093-9mertwj7	123	6	also	also	RB
cord-287093-9mertwj7	123	7	occur	occur	VB
cord-287093-9mertwj7	123	8	in	in	IN
cord-287093-9mertwj7	123	9	virus	virus	NN
cord-287093-9mertwj7	123	10	factories	factory	NNS
cord-287093-9mertwj7	123	11	close	close	JJ
cord-287093-9mertwj7	123	12	to	to	IN
cord-287093-9mertwj7	123	13	the	the	DT
cord-287093-9mertwj7	123	14	microtubule	microtubule	JJ
cord-287093-9mertwj7	123	15	organising	organising	NN
cord-287093-9mertwj7	123	16	centre	centre	NN
cord-287093-9mertwj7	123	17	(	(	-LRB-
cord-287093-9mertwj7	123	18	MTOC	MTOC	NNP
cord-287093-9mertwj7	123	19	)	)	-RRB-
cord-287093-9mertwj7	123	20	[	[	-LRB-
cord-287093-9mertwj7	123	21	40	40	CD
cord-287093-9mertwj7	123	22	]	]	-RRB-
cord-287093-9mertwj7	123	23	.	.	.
cord-287093-9mertwj7	124	1	These	these	DT
cord-287093-9mertwj7	124	2	inclusions	inclusion	NNS
cord-287093-9mertwj7	124	3	lack	lack	VBP
cord-287093-9mertwj7	124	4	cellular	cellular	JJ
cord-287093-9mertwj7	124	5	membranes	membrane	NNS
cord-287093-9mertwj7	124	6	and	and	CC
cord-287093-9mertwj7	124	7	resemble	resemble	JJ
cord-287093-9mertwj7	124	8	inclusions	inclusion	NNS
cord-287093-9mertwj7	124	9	called	call	VBN
cord-287093-9mertwj7	124	10	aggresomes	aggresomes	NNP
cord-287093-9mertwj7	124	11	that	that	DT
cord-287093-9mertwj7	124	12	form	form	NN
cord-287093-9mertwj7	124	13	at	at	IN
cord-287093-9mertwj7	124	14	the	the	DT
cord-287093-9mertwj7	124	15	MTOC	MTOC	NNP
cord-287093-9mertwj7	124	16	in	in	IN
cord-287093-9mertwj7	124	17	response	response	NN
cord-287093-9mertwj7	124	18	to	to	IN
cord-287093-9mertwj7	124	19	protein	protein	NN
cord-287093-9mertwj7	124	20	aggregation	aggregation	NN
cord-287093-9mertwj7	124	21	.	.	.
cord-287093-9mertwj7	125	1	Aggresome	aggresome	JJ
cord-287093-9mertwj7	125	2	inclusions	inclusion	NNS
cord-287093-9mertwj7	125	3	such	such	JJ
cord-287093-9mertwj7	125	4	as	as	IN
cord-287093-9mertwj7	125	5	Lewy	Lewy	NNP
cord-287093-9mertwj7	125	6	and	and	CC
cord-287093-9mertwj7	125	7	Mallory	Mallory	NNP
cord-287093-9mertwj7	125	8	bodies	body	NNS
cord-287093-9mertwj7	125	9	are	be	VBP
cord-287093-9mertwj7	125	10	a	a	DT
cord-287093-9mertwj7	125	11	pathological	pathological	JJ
cord-287093-9mertwj7	125	12	hallmark	hallmark	NN
cord-287093-9mertwj7	125	13	of	of	IN
cord-287093-9mertwj7	125	14	protein	protein	NN
cord-287093-9mertwj7	125	15	misfolding	misfolde	VBG
cord-287093-9mertwj7	125	16	diseases	disease	NNS
cord-287093-9mertwj7	125	17	,	,	,
cord-287093-9mertwj7	125	18	and	and	CC
cord-287093-9mertwj7	125	19	protect	protect	VB
cord-287093-9mertwj7	125	20	cells	cell	NNS
cord-287093-9mertwj7	125	21	from	from	IN
cord-287093-9mertwj7	125	22	the	the	DT
cord-287093-9mertwj7	125	23	damage	damage	NN
cord-287093-9mertwj7	125	24	associated	associate	VBN
cord-287093-9mertwj7	125	25	with	with	IN
cord-287093-9mertwj7	125	26	protein	protein	NN
cord-287093-9mertwj7	125	27	aggregation	aggregation	NN
cord-287093-9mertwj7	125	28	.	.	.
cord-287093-9mertwj7	126	1	Aggresomes	Aggresomes	NNP
cord-287093-9mertwj7	126	2	and	and	CC
cord-287093-9mertwj7	126	3	factories	factory	NNS
cord-287093-9mertwj7	126	4	share	share	VBP
cord-287093-9mertwj7	126	5	many	many	JJ
cord-287093-9mertwj7	126	6	features	feature	NNS
cord-287093-9mertwj7	126	7	in	in	IN
cord-287093-9mertwj7	126	8	common	common	JJ
cord-287093-9mertwj7	126	9	including	include	VBG
cord-287093-9mertwj7	126	10	recruitment	recruitment	NN
cord-287093-9mertwj7	126	11	of	of	IN
cord-287093-9mertwj7	126	12	mitochondria	mitochondrion	NNS
cord-287093-9mertwj7	126	13	,	,	,
cord-287093-9mertwj7	126	14	cellular	cellular	JJ
cord-287093-9mertwj7	126	15	chaperones	chaperone	NNS
cord-287093-9mertwj7	126	16	and	and	CC
cord-287093-9mertwj7	126	17	confinement	confinement	NN
cord-287093-9mertwj7	126	18	within	within	IN
cord-287093-9mertwj7	126	19	cages	cage	NNS
cord-287093-9mertwj7	126	20	of	of	IN
cord-287093-9mertwj7	126	21	rearranged	rearrange	VBN
cord-287093-9mertwj7	126	22	vimentin	vimentin	NN
cord-287093-9mertwj7	126	23	filaments	filament	NNS
cord-287093-9mertwj7	126	24	(	(	-LRB-
cord-287093-9mertwj7	126	25	reviewed	review	VBN
cord-287093-9mertwj7	126	26	in	in	IN
cord-287093-9mertwj7	126	27	[	[	-LRB-
cord-287093-9mertwj7	126	28	40	40	CD
cord-287093-9mertwj7	126	29	,	,	,
cord-287093-9mertwj7	126	30	42	42	CD
cord-287093-9mertwj7	126	31	,	,	,
cord-287093-9mertwj7	126	32	43	43	CD
cord-287093-9mertwj7	126	33	]	]	-RRB-
cord-287093-9mertwj7	126	34	)	)	-RRB-
cord-287093-9mertwj7	126	35	.	.	.
cord-287093-9mertwj7	127	1	Many	many	JJ
cord-287093-9mertwj7	127	2	viruses	virus	NNS
cord-287093-9mertwj7	127	3	are	be	VBP
cord-287093-9mertwj7	127	4	delivered	deliver	VBN
cord-287093-9mertwj7	127	5	to	to	IN
cord-287093-9mertwj7	127	6	the	the	DT
cord-287093-9mertwj7	127	7	MTOC	MTOC	NNP
cord-287093-9mertwj7	127	8	after	after	IN
cord-287093-9mertwj7	127	9	entering	enter	VBG
cord-287093-9mertwj7	127	10	cells	cell	NNS
cord-287093-9mertwj7	127	11	,	,	,
cord-287093-9mertwj7	127	12	and	and	CC
cord-287093-9mertwj7	127	13	in	in	IN
cord-287093-9mertwj7	127	14	common	common	JJ
cord-287093-9mertwj7	127	15	with	with	IN
cord-287093-9mertwj7	127	16	protein	protein	NN
cord-287093-9mertwj7	127	17	aggregates	aggregate	NNS
cord-287093-9mertwj7	127	18	,	,	,
cord-287093-9mertwj7	127	19	this	this	DT
cord-287093-9mertwj7	127	20	involves	involve	VBZ
cord-287093-9mertwj7	127	21	recognition	recognition	NN
cord-287093-9mertwj7	127	22	by	by	IN
cord-287093-9mertwj7	127	23	the	the	DT
cord-287093-9mertwj7	127	24	microtubule	microtubule	NNP
cord-287093-9mertwj7	127	25	motor	motor	NN
cord-287093-9mertwj7	127	26	protein	protein	NN
cord-287093-9mertwj7	127	27	,	,	,
cord-287093-9mertwj7	127	28	dynein	dynein	NNP
cord-287093-9mertwj7	127	29	.	.	.
cord-287093-9mertwj7	128	1	It	-PRON-	PRP
cord-287093-9mertwj7	128	2	is	be	VBZ
cord-287093-9mertwj7	128	3	possible	possible	JJ
cord-287093-9mertwj7	128	4	that	that	IN
cord-287093-9mertwj7	128	5	viruses	virus	NNS
cord-287093-9mertwj7	128	6	may	may	MD
cord-287093-9mertwj7	128	7	appear	appear	VB
cord-287093-9mertwj7	128	8	foreign	foreign	JJ
cord-287093-9mertwj7	128	9	or	or	CC
cord-287093-9mertwj7	128	10	misfolded	misfolde	VBN
cord-287093-9mertwj7	128	11	to	to	IN
cord-287093-9mertwj7	128	12	cells	cell	NNS
cord-287093-9mertwj7	128	13	and	and	CC
cord-287093-9mertwj7	128	14	stimulate	stimulate	VB
cord-287093-9mertwj7	128	15	an	an	DT
cord-287093-9mertwj7	128	16	aggresome	aggresome	JJ
cord-287093-9mertwj7	128	17	response	response	NN
cord-287093-9mertwj7	128	18	.	.	.
cord-287093-9mertwj7	129	1	For	for	IN
cord-287093-9mertwj7	129	2	the	the	DT
cord-287093-9mertwj7	129	3	NCLDV	NCLDV	NNP
cord-287093-9mertwj7	129	4	this	this	DT
cord-287093-9mertwj7	129	5	may	may	MD
cord-287093-9mertwj7	129	6	be	be	VB
cord-287093-9mertwj7	129	7	beneficial	beneficial	JJ
cord-287093-9mertwj7	129	8	and	and	CC
cord-287093-9mertwj7	129	9	provide	provide	VB
cord-287093-9mertwj7	129	10	a	a	DT
cord-287093-9mertwj7	129	11	site	site	NN
cord-287093-9mertwj7	129	12	for	for	IN
cord-287093-9mertwj7	129	13	replication	replication	NN
cord-287093-9mertwj7	129	14	,	,	,
cord-287093-9mertwj7	129	15	for	for	IN
cord-287093-9mertwj7	129	16	other	other	JJ
cord-287093-9mertwj7	129	17	viruses	virus	NNS
cord-287093-9mertwj7	129	18	it	-PRON-	PRP
cord-287093-9mertwj7	129	19	may	may	MD
cord-287093-9mertwj7	129	20	lead	lead	VB
cord-287093-9mertwj7	129	21	to	to	IN
cord-287093-9mertwj7	129	22	confinement	confinement	NN
cord-287093-9mertwj7	129	23	at	at	IN
cord-287093-9mertwj7	129	24	the	the	DT
cord-287093-9mertwj7	129	25	MTOC	MTOC	NNP
cord-287093-9mertwj7	129	26	and	and	CC
cord-287093-9mertwj7	129	27	degradation	degradation	NN
cord-287093-9mertwj7	129	28	.	.	.
cord-287093-9mertwj7	130	1	Delivery	delivery	NN
cord-287093-9mertwj7	130	2	of	of	IN
cord-287093-9mertwj7	130	3	incoming	incoming	JJ
cord-287093-9mertwj7	130	4	African	african	JJ
cord-287093-9mertwj7	130	5	swine	swine	NN
cord-287093-9mertwj7	130	6	fever	fever	NN
cord-287093-9mertwj7	130	7	virus	virus	NN
cord-287093-9mertwj7	130	8	(	(	-LRB-
cord-287093-9mertwj7	130	9	ASFV	ASFV	NNP
cord-287093-9mertwj7	130	10	)	)	-RRB-
cord-287093-9mertwj7	130	11	to	to	IN
cord-287093-9mertwj7	130	12	the	the	DT
cord-287093-9mertwj7	130	13	MTOC	MTOC	NNP
cord-287093-9mertwj7	130	14	is	be	VBZ
cord-287093-9mertwj7	130	15	important	important	JJ
cord-287093-9mertwj7	130	16	for	for	IN
cord-287093-9mertwj7	130	17	the	the	DT
cord-287093-9mertwj7	130	18	initiation	initiation	NN
cord-287093-9mertwj7	130	19	of	of	IN
cord-287093-9mertwj7	130	20	replication	replication	NN
cord-287093-9mertwj7	130	21	[	[	-LRB-
cord-287093-9mertwj7	130	22	41	41	CD
cord-287093-9mertwj7	130	23	]	]	-RRB-
cord-287093-9mertwj7	130	24	and	and	CC
cord-287093-9mertwj7	130	25	replication	replication	NN
cord-287093-9mertwj7	130	26	of	of	IN
cord-287093-9mertwj7	130	27	both	both	CC
cord-287093-9mertwj7	130	28	the	the	DT
cord-287093-9mertwj7	130	29	ASFV	ASFV	NNP
cord-287093-9mertwj7	130	30	and	and	CC
cord-287093-9mertwj7	130	31	the	the	DT
cord-287093-9mertwj7	130	32	iridovirus	iridovirus	NNP
cord-287093-9mertwj7	130	33	frog	frog	NNP
cord-287093-9mertwj7	130	34	virus	virus	NN
cord-287093-9mertwj7	130	35	3	3	CD
cord-287093-9mertwj7	130	36	appears	appear	VBZ
cord-287093-9mertwj7	130	37	to	to	TO
cord-287093-9mertwj7	130	38	require	require	VB
cord-287093-9mertwj7	130	39	rearrangement	rearrangement	NN
cord-287093-9mertwj7	130	40	of	of	IN
cord-287093-9mertwj7	130	41	vimentin	vimentin	NN
cord-287093-9mertwj7	130	42	[	[	-LRB-
cord-287093-9mertwj7	130	43	44	44	CD
cord-287093-9mertwj7	130	44	,	,	,
cord-287093-9mertwj7	130	45	45	45	CD
cord-287093-9mertwj7	130	46	]	]	-RRB-
cord-287093-9mertwj7	130	47	.	.	.
cord-287093-9mertwj7	131	1	Vimentin	Vimentin	NNP
cord-287093-9mertwj7	131	2	may	may	MD
cord-287093-9mertwj7	131	3	provide	provide	VB
cord-287093-9mertwj7	131	4	a	a	DT
cord-287093-9mertwj7	131	5	scaffold	scaffold	NN
cord-287093-9mertwj7	131	6	to	to	TO
cord-287093-9mertwj7	131	7	prevent	prevent	VB
cord-287093-9mertwj7	131	8	diffusion	diffusion	NN
cord-287093-9mertwj7	131	9	of	of	IN
cord-287093-9mertwj7	131	10	viral	viral	JJ
cord-287093-9mertwj7	131	11	components	component	NNS
cord-287093-9mertwj7	131	12	into	into	IN
cord-287093-9mertwj7	131	13	the	the	DT
cord-287093-9mertwj7	131	14	cytoplasm	cytoplasm	NN
cord-287093-9mertwj7	131	15	.	.	.
cord-287093-9mertwj7	132	1	DNA	DNA	NNP
cord-287093-9mertwj7	132	2	and	and	CC
cord-287093-9mertwj7	132	3	RNA	RNA	NNP
cord-287093-9mertwj7	132	4	are	be	VBP
cord-287093-9mertwj7	132	5	spatially	spatially	RB
cord-287093-9mertwj7	132	6	separated	separate	VBN
cord-287093-9mertwj7	132	7	within	within	IN
cord-287093-9mertwj7	132	8	vaccinia	vaccinia	NN
cord-287093-9mertwj7	132	9	virus	virus	NN
cord-287093-9mertwj7	132	10	(	(	-LRB-
cord-287093-9mertwj7	132	11	VACV	VACV	NNP
cord-287093-9mertwj7	132	12	)	)	-RRB-
cord-287093-9mertwj7	132	13	and	and	CC
cord-287093-9mertwj7	133	1	ASFV	ASFV	NNP
cord-287093-9mertwj7	133	2	factories	factory	NNS
cord-287093-9mertwj7	133	3	[	[	-LRB-
cord-287093-9mertwj7	133	4	46	46	CD
cord-287093-9mertwj7	133	5	,	,	,
cord-287093-9mertwj7	133	6	47	47	CD
cord-287093-9mertwj7	133	7	]	]	-RRB-
cord-287093-9mertwj7	133	8	and	and	CC
cord-287093-9mertwj7	133	9	individual	individual	JJ
cord-287093-9mertwj7	133	10	factories	factory	NNS
cord-287093-9mertwj7	133	11	appear	appear	VBP
cord-287093-9mertwj7	133	12	to	to	TO
cord-287093-9mertwj7	133	13	be	be	VB
cord-287093-9mertwj7	133	14	distinct	distinct	JJ
cord-287093-9mertwj7	133	15	entities	entity	NNS
cord-287093-9mertwj7	133	16	within	within	IN
cord-287093-9mertwj7	133	17	the	the	DT
cord-287093-9mertwj7	133	18	cell	cell	NN
cord-287093-9mertwj7	133	19	.	.	.
cord-287093-9mertwj7	134	1	Although	although	IN
cord-287093-9mertwj7	134	2	virus	virus	NN
cord-287093-9mertwj7	134	3	factories	factory	NNS
cord-287093-9mertwj7	134	4	recruit	recruit	VBP
cord-287093-9mertwj7	134	5	many	many	JJ
cord-287093-9mertwj7	134	6	host	host	NN
cord-287093-9mertwj7	134	7	-	-	HYPH
cord-287093-9mertwj7	134	8	cell	cell	NN
cord-287093-9mertwj7	134	9	proteins	protein	NNS
cord-287093-9mertwj7	134	10	to	to	TO
cord-287093-9mertwj7	134	11	facilitate	facilitate	VB
cord-287093-9mertwj7	134	12	their	-PRON-	PRP$
cord-287093-9mertwj7	134	13	replication	replication	NN
cord-287093-9mertwj7	134	14	,	,	,
cord-287093-9mertwj7	134	15	factories	factory	NNS
cord-287093-9mertwj7	134	16	also	also	RB
cord-287093-9mertwj7	134	17	represent	represent	VBP
cord-287093-9mertwj7	134	18	effector	effector	JJ
cord-287093-9mertwj7	134	19	sites	site	NNS
cord-287093-9mertwj7	134	20	for	for	IN
cord-287093-9mertwj7	134	21	antiviral	antiviral	JJ
cord-287093-9mertwj7	134	22	activity	activity	NN
cord-287093-9mertwj7	134	23	as	as	IN
cord-287093-9mertwj7	134	24	VACV	VACV	NNP
cord-287093-9mertwj7	134	25	and	and	CC
cord-287093-9mertwj7	134	26	ASFV	ASFV	NNP
cord-287093-9mertwj7	134	27	replication	replication	NN
cord-287093-9mertwj7	134	28	sites	site	NNS
cord-287093-9mertwj7	134	29	are	be	VBP
cord-287093-9mertwj7	134	30	targeted	target	VBN
cord-287093-9mertwj7	134	31	by	by	IN
cord-287093-9mertwj7	134	32	stress	stress	NN
cord-287093-9mertwj7	134	33	granule	granule	NN
cord-287093-9mertwj7	134	34	components	component	NNS
cord-287093-9mertwj7	134	35	and	and	CC
cord-287093-9mertwj7	134	36	Mx	Mx	NNP
cord-287093-9mertwj7	134	37	proteins	protein	NNS
cord-287093-9mertwj7	134	38	respectively	respectively	RB
cord-287093-9mertwj7	134	39	[	[	-LRB-
cord-287093-9mertwj7	134	40	48	48	CD
cord-287093-9mertwj7	134	41	,	,	,
cord-287093-9mertwj7	134	42	49	49	CD
cord-287093-9mertwj7	134	43	]	]	-RRB-
cord-287093-9mertwj7	134	44	.	.	.
cord-287093-9mertwj7	135	1	A	a	DT
cord-287093-9mertwj7	135	2	number	number	NN
cord-287093-9mertwj7	135	3	of	of	IN
cord-287093-9mertwj7	135	4	clear	clear	JJ
cord-287093-9mertwj7	135	5	similarities	similarity	NNS
cord-287093-9mertwj7	135	6	between	between	IN
cord-287093-9mertwj7	135	7	the	the	DT
cord-287093-9mertwj7	135	8	membrane	membrane	NN
cord-287093-9mertwj7	135	9	rearrangements	rearrangement	NNS
cord-287093-9mertwj7	135	10	generated	generate	VBN
cord-287093-9mertwj7	135	11	by	by	IN
cord-287093-9mertwj7	135	12	the	the	DT
cord-287093-9mertwj7	135	13	positive	positive	JJ
cord-287093-9mertwj7	135	14	strand	strand	NN
cord-287093-9mertwj7	135	15	RNA	RNA	NNP
cord-287093-9mertwj7	135	16	viruses	virus	NNS
cord-287093-9mertwj7	135	17	are	be	VBP
cord-287093-9mertwj7	135	18	beginning	begin	VBG
cord-287093-9mertwj7	135	19	to	to	TO
cord-287093-9mertwj7	135	20	emerge	emerge	VB
cord-287093-9mertwj7	135	21	[	[	-LRB-
cord-287093-9mertwj7	135	22	1	1	CD
cord-287093-9mertwj7	135	23	,	,	,
cord-287093-9mertwj7	135	24	2	2	CD
cord-287093-9mertwj7	135	25	]	]	-RRB-
cord-287093-9mertwj7	135	26	and	and	CC
cord-287093-9mertwj7	135	27	these	these	DT
cord-287093-9mertwj7	135	28	are	be	VBP
cord-287093-9mertwj7	135	29	shared	share	VBN
cord-287093-9mertwj7	135	30	between	between	IN
cord-287093-9mertwj7	135	31	animal	animal	NN
cord-287093-9mertwj7	135	32	and	and	CC
cord-287093-9mertwj7	135	33	plant	plant	NN
cord-287093-9mertwj7	135	34	viruses	virus	NNS
cord-287093-9mertwj7	135	35	.	.	.
cord-287093-9mertwj7	136	1	Spherules	spherule	NNS
cord-287093-9mertwj7	136	2	and	and	CC
cord-287093-9mertwj7	136	3	DMVs	dmv	NNS
cord-287093-9mertwj7	136	4	differ	differ	VBP
cord-287093-9mertwj7	136	5	morphologically	morphologically	RB
cord-287093-9mertwj7	136	6	but	but	CC
cord-287093-9mertwj7	136	7	may	may	MD
cord-287093-9mertwj7	136	8	be	be	VB
cord-287093-9mertwj7	136	9	formed	form	VBN
cord-287093-9mertwj7	136	10	by	by	IN
cord-287093-9mertwj7	136	11	similar	similar	JJ
cord-287093-9mertwj7	136	12	mechanisms	mechanism	NNS
cord-287093-9mertwj7	136	13	involving	involve	VBG
cord-287093-9mertwj7	136	14	ordered	order	VBN
cord-287093-9mertwj7	136	15	assembly	assembly	NN
cord-287093-9mertwj7	136	16	of	of	IN
cord-287093-9mertwj7	136	17	replicase	replicase	NNP
cord-287093-9mertwj7	136	18	proteins	protein	NNS
cord-287093-9mertwj7	136	19	on	on	IN
cord-287093-9mertwj7	136	20	membrane	membrane	NN
cord-287093-9mertwj7	136	21	-	-	HYPH
cord-287093-9mertwj7	136	22	bound	bind	VBN
cord-287093-9mertwj7	136	23	organelles	organelle	NNS
cord-287093-9mertwj7	136	24	leading	lead	VBG
cord-287093-9mertwj7	136	25	to	to	IN
cord-287093-9mertwj7	136	26	membrane	membrane	NN
cord-287093-9mertwj7	136	27	invagination	invagination	NN
cord-287093-9mertwj7	136	28	(	(	-LRB-
cord-287093-9mertwj7	136	29	Figure	figure	NN
cord-287093-9mertwj7	136	30	1	1	CD
cord-287093-9mertwj7	136	31	)	)	-RRB-
cord-287093-9mertwj7	136	32	.	.	.
cord-287093-9mertwj7	137	1	DMVs	dmv	NNS
cord-287093-9mertwj7	137	2	may	may	MD
cord-287093-9mertwj7	137	3	be	be	VB
cord-287093-9mertwj7	137	4	modified	modify	VBN
cord-287093-9mertwj7	137	5	spherules	spherule	NNS
cord-287093-9mertwj7	137	6	where	where	WRB
cord-287093-9mertwj7	137	7	close	close	JJ
cord-287093-9mertwj7	137	8	apposition	apposition	NN
cord-287093-9mertwj7	137	9	of	of	IN
cord-287093-9mertwj7	137	10	ER	er	NN
cord-287093-9mertwj7	137	11	-	-	HYPH
cord-287093-9mertwj7	137	12	derived	derive	VBN
cord-287093-9mertwj7	137	13	membranes	membrane	NNS
cord-287093-9mertwj7	137	14	follows	follow	VBZ
cord-287093-9mertwj7	137	15	initial	initial	JJ
cord-287093-9mertwj7	137	16	invagination	invagination	NN
cord-287093-9mertwj7	137	17	into	into	IN
cord-287093-9mertwj7	137	18	the	the	DT
cord-287093-9mertwj7	137	19	ER	ER	NNP
cord-287093-9mertwj7	137	20	lumen	lumen	NN
cord-287093-9mertwj7	137	21	.	.	.
cord-287093-9mertwj7	138	1	For	for	IN
cord-287093-9mertwj7	138	2	cornaviruses	cornaviruse	NNS
cord-287093-9mertwj7	138	3	,	,	,
cord-287093-9mertwj7	138	4	and	and	CC
cord-287093-9mertwj7	138	5	possibly	possibly	RB
cord-287093-9mertwj7	138	6	picornaviruses	picornaviruses	NNP
cord-287093-9mertwj7	138	7	,	,	,
cord-287093-9mertwj7	138	8	this	this	DT
cord-287093-9mertwj7	138	9	may	may	MD
cord-287093-9mertwj7	138	10	result	result	VB
cord-287093-9mertwj7	138	11	in	in	IN
cord-287093-9mertwj7	138	12	loss	loss	NN
cord-287093-9mertwj7	138	13	of	of	IN
cord-287093-9mertwj7	138	14	the	the	DT
cord-287093-9mertwj7	138	15	pore	pore	NN
cord-287093-9mertwj7	138	16	connecting	connect	VBG
cord-287093-9mertwj7	138	17	the	the	DT
cord-287093-9mertwj7	138	18	spherule	spherule	NN
cord-287093-9mertwj7	138	19	to	to	IN
cord-287093-9mertwj7	138	20	the	the	DT
cord-287093-9mertwj7	138	21	cytosol	cytosol	NN
cord-287093-9mertwj7	138	22	and	and	CC
cord-287093-9mertwj7	138	23	conversion	conversion	NN
cord-287093-9mertwj7	138	24	of	of	IN
cord-287093-9mertwj7	138	25	the	the	DT
cord-287093-9mertwj7	138	26	spherule	spherule	NNP
cord-287093-9mertwj7	138	27	into	into	IN
cord-287093-9mertwj7	138	28	a	a	DT
cord-287093-9mertwj7	138	29	site	site	NN
cord-287093-9mertwj7	138	30	for	for	IN
cord-287093-9mertwj7	138	31	storage	storage	NN
cord-287093-9mertwj7	138	32	of	of	IN
cord-287093-9mertwj7	138	33	viral	viral	JJ
cord-287093-9mertwj7	138	34	RNA	RNA	NNP
cord-287093-9mertwj7	138	35	to	to	TO
cord-287093-9mertwj7	138	36	suppress	suppress	VB
cord-287093-9mertwj7	138	37	innate	innate	JJ
cord-287093-9mertwj7	138	38	immune	immune	JJ
cord-287093-9mertwj7	138	39	responses	response	NNS
cord-287093-9mertwj7	138	40	to	to	IN
cord-287093-9mertwj7	138	41	double	double	RB
cord-287093-9mertwj7	138	42	-	-	HYPH
cord-287093-9mertwj7	138	43	stranded	strand	VBN
cord-287093-9mertwj7	138	44	RNA	RNA	NNP
cord-287093-9mertwj7	138	45	.	.	.
cord-287093-9mertwj7	139	1	The	the	DT
cord-287093-9mertwj7	139	2	site	site	NN
cord-287093-9mertwj7	139	3	of	of	IN
cord-287093-9mertwj7	139	4	spherule	spherule	NNP
cord-287093-9mertwj7	139	5	formation	formation	NN
cord-287093-9mertwj7	139	6	differs	differ	VBZ
cord-287093-9mertwj7	139	7	between	between	IN
cord-287093-9mertwj7	139	8	viruses	virus	NNS
cord-287093-9mertwj7	139	9	(	(	-LRB-
cord-287093-9mertwj7	139	10	Figure	figure	NN
cord-287093-9mertwj7	139	11	2	2	CD
cord-287093-9mertwj7	139	12	)	)	-RRB-
cord-287093-9mertwj7	139	13	and	and	CC
cord-287093-9mertwj7	139	14	is	be	VBZ
cord-287093-9mertwj7	139	15	determined	determine	VBN
cord-287093-9mertwj7	139	16	by	by	IN
cord-287093-9mertwj7	139	17	membrane	membrane	NN
cord-287093-9mertwj7	139	18	targeting	target	VBG
cord-287093-9mertwj7	139	19	sequences	sequence	NNS
cord-287093-9mertwj7	139	20	in	in	IN
cord-287093-9mertwj7	139	21	the	the	DT
cord-287093-9mertwj7	139	22	nonstructural	nonstructural	JJ
cord-287093-9mertwj7	139	23	proteins	protein	NNS
cord-287093-9mertwj7	139	24	that	that	WDT
cord-287093-9mertwj7	139	25	recruit	recruit	VBP
cord-287093-9mertwj7	139	26	the	the	DT
cord-287093-9mertwj7	139	27	RdRp	RdRp	NNP
cord-287093-9mertwj7	139	28	.	.	.
cord-287093-9mertwj7	140	1	This	this	DT
cord-287093-9mertwj7	140	2	has	have	VBZ
cord-287093-9mertwj7	140	3	been	be	VBN
cord-287093-9mertwj7	140	4	demonstrated	demonstrate	VBN
cord-287093-9mertwj7	140	5	by	by	IN
cord-287093-9mertwj7	140	6	the	the	DT
cord-287093-9mertwj7	140	7	work	work	NN
cord-287093-9mertwj7	140	8	of	of	IN
cord-287093-9mertwj7	140	9	Miller	Miller	NNP
cord-287093-9mertwj7	140	10	et	et	NNP
cord-287093-9mertwj7	140	11	al	al	NNP
cord-287093-9mertwj7	140	12	.	.	.
cord-287093-9mertwj7	141	1	who	who	WP
cord-287093-9mertwj7	141	2	could	could	MD
cord-287093-9mertwj7	141	3	retarget	retarget	VB
cord-287093-9mertwj7	141	4	FHV	FHV	NNP
cord-287093-9mertwj7	141	5	replication	replication	NN
cord-287093-9mertwj7	141	6	complexes	complex	NNS
cord-287093-9mertwj7	141	7	from	from	IN
cord-287093-9mertwj7	141	8	the	the	DT
cord-287093-9mertwj7	141	9	mitochondria	mitochondrion	NNS
cord-287093-9mertwj7	141	10	to	to	IN
cord-287093-9mertwj7	141	11	the	the	DT
cord-287093-9mertwj7	141	12	ER	ER	NNP
cord-287093-9mertwj7	141	13	in	in	IN
cord-287093-9mertwj7	141	14	yeast	yeast	NN
cord-287093-9mertwj7	141	15	[	[	-LRB-
cord-287093-9mertwj7	141	16	50	50	CD
cord-287093-9mertwj7	141	17	]	]	-RRB-
cord-287093-9mertwj7	141	18	.	.	.
cord-287093-9mertwj7	142	1	Recent	recent	JJ
cord-287093-9mertwj7	142	2	work	work	NN
cord-287093-9mertwj7	142	3	has	have	VBZ
cord-287093-9mertwj7	142	4	shown	show	VBN
cord-287093-9mertwj7	142	5	that	that	IN
cord-287093-9mertwj7	142	6	recruitment	recruitment	NN
cord-287093-9mertwj7	142	7	of	of	IN
cord-287093-9mertwj7	142	8	RdRp	RdRp	NNP
cord-287093-9mertwj7	142	9	may	may	MD
cord-287093-9mertwj7	142	10	also	also	RB
cord-287093-9mertwj7	142	11	involve	involve	VB
cord-287093-9mertwj7	142	12	modification	modification	NN
cord-287093-9mertwj7	142	13	of	of	IN
cord-287093-9mertwj7	142	14	membrane	membrane	NN
cord-287093-9mertwj7	142	15	lipids	lipid	NNS
cord-287093-9mertwj7	142	16	by	by	IN
cord-287093-9mertwj7	142	17	Arf1-dependent	Arf1-dependent	NNP
cord-287093-9mertwj7	142	18	recruitment	recruitment	NN
cord-287093-9mertwj7	142	19	of	of	IN
cord-287093-9mertwj7	142	20	PI4KIIIb	PI4KIIIb	NNP
cord-287093-9mertwj7	142	21	to	to	IN
cord-287093-9mertwj7	142	22	membranes	membrane	NNS
cord-287093-9mertwj7	142	23	to	to	TO
cord-287093-9mertwj7	142	24	generate	generate	VB
cord-287093-9mertwj7	142	25	PI4-P.	PI4-P.	NNP
cord-287093-9mertwj7	143	1	This	this	DT
cord-287093-9mertwj7	143	2	mechanism	mechanism	NN
cord-287093-9mertwj7	143	3	is	be	VBZ
cord-287093-9mertwj7	143	4	shared	share	VBN
cord-287093-9mertwj7	143	5	between	between	IN
cord-287093-9mertwj7	143	6	the	the	DT
cord-287093-9mertwj7	143	7	enteroviruses	enterovirus	NNS
cord-287093-9mertwj7	143	8	of	of	IN
cord-287093-9mertwj7	143	9	the	the	DT
cord-287093-9mertwj7	143	10	picornavirus	picornavirus	NNP
cord-287093-9mertwj7	143	11	supergroup	supergroup	NNP
cord-287093-9mertwj7	143	12	and	and	CC
cord-287093-9mertwj7	143	13	the	the	DT
cord-287093-9mertwj7	143	14	flavivirus	flavivirus	JJ
cord-287093-9mertwj7	143	15	HCV	HCV	NNP
cord-287093-9mertwj7	143	16	[	[	-LRB-
cord-287093-9mertwj7	143	17	25	25	CD
cord-287093-9mertwj7	143	18	,	,	,
cord-287093-9mertwj7	143	19	31	31	CD
cord-287093-9mertwj7	143	20	]	]	-RRB-
cord-287093-9mertwj7	143	21	.	.	.
cord-287093-9mertwj7	144	1	The	the	DT
cord-287093-9mertwj7	144	2	membrane	membrane	NN
cord-287093-9mertwj7	144	3	vesicles	vesicle	NNS
cord-287093-9mertwj7	144	4	generated	generate	VBN
cord-287093-9mertwj7	144	5	by	by	IN
cord-287093-9mertwj7	144	6	picornaviruses	picornavirus	NNS
cord-287093-9mertwj7	144	7	are	be	VBP
cord-287093-9mertwj7	144	8	most	most	RBS
cord-287093-9mertwj7	144	9	heterogeneous	heterogeneous	JJ
cord-287093-9mertwj7	144	10	and	and	CC
cord-287093-9mertwj7	144	11	varied	varied	JJ
cord-287093-9mertwj7	144	12	between	between	IN
cord-287093-9mertwj7	144	13	subgroups	subgroup	NNS
cord-287093-9mertwj7	144	14	and	and	CC
cord-287093-9mertwj7	144	15	may	may	MD
cord-287093-9mertwj7	144	16	be	be	VB
cord-287093-9mertwj7	144	17	derived	derive	VBN
cord-287093-9mertwj7	144	18	from	from	IN
cord-287093-9mertwj7	144	19	membrane	membrane	NN
cord-287093-9mertwj7	144	20	compartments	compartment	NNS
cord-287093-9mertwj7	144	21	that	that	DT
cord-287093-9mertwj7	144	22	fragment	fragment	NN
cord-287093-9mertwj7	144	23	during	during	IN
cord-287093-9mertwj7	144	24	infection	infection	NN
cord-287093-9mertwj7	144	25	,	,	,
cord-287093-9mertwj7	144	26	rather	rather	RB
cord-287093-9mertwj7	144	27	than	than	IN
cord-287093-9mertwj7	144	28	be	be	VB
cord-287093-9mertwj7	144	29	formed	form	VBN
cord-287093-9mertwj7	144	30	for	for	IN
cord-287093-9mertwj7	144	31	virus	virus	NN
cord-287093-9mertwj7	144	32	replication	replication	NN
cord-287093-9mertwj7	144	33	.	.	.
cord-287093-9mertwj7	145	1	It	-PRON-	PRP
cord-287093-9mertwj7	145	2	is	be	VBZ
cord-287093-9mertwj7	145	3	uncertain	uncertain	JJ
cord-287093-9mertwj7	145	4	which	which	WDT
cord-287093-9mertwj7	145	5	Sites	site	NNS
cord-287093-9mertwj7	145	6	of	of	IN
cord-287093-9mertwj7	145	7	replication	replication	NN
cord-287093-9mertwj7	145	8	generated	generate	VBN
cord-287093-9mertwj7	145	9	by	by	IN
cord-287093-9mertwj7	145	10	plant	plant	NN
cord-287093-9mertwj7	145	11	and	and	CC
cord-287093-9mertwj7	145	12	animal	animal	NN
cord-287093-9mertwj7	145	13	viruses	virus	NNS
cord-287093-9mertwj7	145	14	.	.	.
cord-287093-9mertwj7	146	1	The	the	DT
cord-287093-9mertwj7	146	2	diagram	diagram	NN
cord-287093-9mertwj7	146	3	is	be	VBZ
cord-287093-9mertwj7	146	4	in	in	IN
cord-287093-9mertwj7	146	5	two	two	CD
cord-287093-9mertwj7	146	6	halves	half	NNS
cord-287093-9mertwj7	146	7	.	.	.
cord-287093-9mertwj7	147	1	The	the	DT
cord-287093-9mertwj7	147	2	left	left	NN
cord-287093-9mertwj7	147	3	represents	represent	VBZ
cord-287093-9mertwj7	147	4	a	a	DT
cord-287093-9mertwj7	147	5	plant	plant	NN
cord-287093-9mertwj7	147	6	cell	cell	NN
cord-287093-9mertwj7	147	7	and	and	CC
cord-287093-9mertwj7	147	8	is	be	VBZ
cord-287093-9mertwj7	147	9	surrounded	surround	VBN
cord-287093-9mertwj7	147	10	by	by	IN
cord-287093-9mertwj7	147	11	a	a	DT
cord-287093-9mertwj7	147	12	cell	cell	NN
cord-287093-9mertwj7	147	13	wall	wall	NN
cord-287093-9mertwj7	147	14	(	(	-LRB-
cord-287093-9mertwj7	147	15	green	green	NNP
cord-287093-9mertwj7	147	16	)	)	-RRB-
cord-287093-9mertwj7	147	17	.	.	.
cord-287093-9mertwj7	148	1	Viral	viral	JJ
cord-287093-9mertwj7	148	2	replication	replication	NN
cord-287093-9mertwj7	148	3	complexes	complex	NNS
cord-287093-9mertwj7	148	4	(	(	-LRB-
cord-287093-9mertwj7	148	5	VRC	VRC	NNP
cord-287093-9mertwj7	148	6	)	)	-RRB-
cord-287093-9mertwj7	148	7	are	be	VBP
cord-287093-9mertwj7	148	8	generated	generate	VBN
cord-287093-9mertwj7	148	9	by	by	IN
cord-287093-9mertwj7	148	10	plant	plant	NN
cord-287093-9mertwj7	148	11	viruses	virus	NNS
cord-287093-9mertwj7	148	12	at	at	IN
cord-287093-9mertwj7	148	13	the	the	DT
cord-287093-9mertwj7	148	14	ER	er	NN
cord-287093-9mertwj7	148	15	,	,	,
cord-287093-9mertwj7	148	16	chloroplast	chloroplast	NN
cord-287093-9mertwj7	148	17	and	and	CC
cord-287093-9mertwj7	148	18	peroxisomes	peroxisome	NNS
cord-287093-9mertwj7	148	19	.	.	.
cord-287093-9mertwj7	149	1	Tobamovirus	Tobamovirus	NNP
cord-287093-9mertwj7	149	2	VRCs	vrc	NNS
cord-287093-9mertwj7	149	3	are	be	VBP
cord-287093-9mertwj7	149	4	initiated	initiate	VBN
cord-287093-9mertwj7	149	5	at	at	IN
cord-287093-9mertwj7	149	6	the	the	DT
cord-287093-9mertwj7	149	7	tonoplast	tonoplast	NNP
cord-287093-9mertwj7	149	8	.	.	.
cord-287093-9mertwj7	150	1	VRCs	VRCs	NNP
cord-287093-9mertwj7	150	2	of	of	IN
cord-287093-9mertwj7	150	3	many	many	JJ
cord-287093-9mertwj7	150	4	plant	plant	NN
cord-287093-9mertwj7	150	5	viruses	virus	NNS
cord-287093-9mertwj7	150	6	can	can	MD
cord-287093-9mertwj7	150	7	be	be	VB
cord-287093-9mertwj7	150	8	transported	transport	VBN
cord-287093-9mertwj7	150	9	within	within	IN
cord-287093-9mertwj7	150	10	the	the	DT
cord-287093-9mertwj7	150	11	cell	cell	NN
cord-287093-9mertwj7	150	12	along	along	IN
cord-287093-9mertwj7	150	13	the	the	DT
cord-287093-9mertwj7	150	14	ER	er	NN
cord-287093-9mertwj7	150	15	and	and	CC
cord-287093-9mertwj7	150	16	between	between	IN
cord-287093-9mertwj7	150	17	cells	cell	NNS
cord-287093-9mertwj7	150	18	using	use	VBG
cord-287093-9mertwj7	150	19	the	the	DT
cord-287093-9mertwj7	150	20	plasmodesmata	plasmodesmata	NN
cord-287093-9mertwj7	150	21	.	.	.
cord-287093-9mertwj7	151	1	This	this	DT
cord-287093-9mertwj7	151	2	movement	movement	NN
cord-287093-9mertwj7	151	3	is	be	VBZ
cord-287093-9mertwj7	151	4	directed	direct	VBN
cord-287093-9mertwj7	151	5	by	by	IN
cord-287093-9mertwj7	151	6	plant	plant	NN
cord-287093-9mertwj7	151	7	movement	movement	NN
cord-287093-9mertwj7	151	8	proteins	protein	NNS
cord-287093-9mertwj7	151	9	(	(	-LRB-
cord-287093-9mertwj7	151	10	MP	MP	NNP
cord-287093-9mertwj7	151	11	)	)	-RRB-
cord-287093-9mertwj7	151	12	;	;	:
cord-287093-9mertwj7	151	13	see	see	VB
cord-287093-9mertwj7	151	14	accompanying	accompany	VBG
cord-287093-9mertwj7	151	15	article	article	NN
cord-287093-9mertwj7	151	16	by	by	IN
cord-287093-9mertwj7	151	17	Jeanmarie	Jeanmarie	NNP
cord-287093-9mertwj7	151	18	Verchot	Verchot	NNP
cord-287093-9mertwj7	151	19	for	for	IN
cord-287093-9mertwj7	151	20	details	detail	NNS
cord-287093-9mertwj7	151	21	.	.	.
cord-287093-9mertwj7	152	1	The	the	DT
cord-287093-9mertwj7	152	2	right	right	NN
cord-287093-9mertwj7	152	3	represents	represent	VBZ
cord-287093-9mertwj7	152	4	an	an	DT
cord-287093-9mertwj7	152	5	animal	animal	NN
cord-287093-9mertwj7	152	6	cell	cell	NN
cord-287093-9mertwj7	152	7	.	.	.
cord-287093-9mertwj7	153	1	Alphavirus	Alphavirus	NNP
cord-287093-9mertwj7	153	2	and	and	CC
cord-287093-9mertwj7	153	3	nodaviruses	nodaviruses	NNP
cord-287093-9mertwj7	153	4	form	form	NN
cord-287093-9mertwj7	153	5	spherules	spherule	NNS
cord-287093-9mertwj7	153	6	at	at	IN
cord-287093-9mertwj7	153	7	the	the	DT
cord-287093-9mertwj7	153	8	endosomal	endosomal	NNP
cord-287093-9mertwj7	153	9	-	-	HYPH
cord-287093-9mertwj7	153	10	lysosomal	lysosomal	VBG
cord-287093-9mertwj7	153	11	system	system	NN
cord-287093-9mertwj7	153	12	and	and	CC
cord-287093-9mertwj7	153	13	mitochondria	mitochondria	NN
cord-287093-9mertwj7	153	14	respectively	respectively	RB
cord-287093-9mertwj7	153	15	.	.	.
cord-287093-9mertwj7	154	1	Coronavirus	Coronavirus	NNP
cord-287093-9mertwj7	154	2	,	,	,
cord-287093-9mertwj7	154	3	arterivirus	arterivirus	NNP
cord-287093-9mertwj7	154	4	and	and	CC
cord-287093-9mertwj7	154	5	flaviviruses	flaviviruses	NNP
cord-287093-9mertwj7	154	6	form	form	VBP
cord-287093-9mertwj7	154	7	double	double	JJ
cord-287093-9mertwj7	154	8	membrane	membrane	NN
cord-287093-9mertwj7	154	9	vesicles	vesicle	NNS
cord-287093-9mertwj7	154	10	(	(	-LRB-
cord-287093-9mertwj7	154	11	DMVs	dmv	NNS
cord-287093-9mertwj7	154	12	)	)	-RRB-
cord-287093-9mertwj7	154	13	from	from	IN
cord-287093-9mertwj7	154	14	the	the	DT
cord-287093-9mertwj7	154	15	ER	ER	NNP
cord-287093-9mertwj7	154	16	and	and	CC
cord-287093-9mertwj7	154	17	coronaviruses	coronaviruse	NNS
cord-287093-9mertwj7	154	18	and	and	CC
cord-287093-9mertwj7	154	19	arteriviruses	arteriviruse	NNS
cord-287093-9mertwj7	154	20	also	also	RB
cord-287093-9mertwj7	154	21	form	form	VBP
cord-287093-9mertwj7	154	22	vesicle	vesicle	NN
cord-287093-9mertwj7	154	23	packets	packet	NNS
cord-287093-9mertwj7	154	24	(	(	-LRB-
cord-287093-9mertwj7	154	25	VPs	VPs	NNP
cord-287093-9mertwj7	154	26	)	)	-RRB-
cord-287093-9mertwj7	154	27	.	.	.
cord-287093-9mertwj7	155	1	The	the	DT
cord-287093-9mertwj7	155	2	membranes	membrane	NNS
cord-287093-9mertwj7	155	3	used	use	VBN
cord-287093-9mertwj7	155	4	to	to	TO
cord-287093-9mertwj7	155	5	generate	generate	VB
cord-287093-9mertwj7	155	6	sites	site	NNS
cord-287093-9mertwj7	155	7	of	of	IN
cord-287093-9mertwj7	155	8	picornavirus	picornavirus	NN
cord-287093-9mertwj7	155	9	replication	replication	NN
cord-287093-9mertwj7	155	10	are	be	VBP
cord-287093-9mertwj7	155	11	unclear	unclear	JJ
cord-287093-9mertwj7	155	12	but	but	CC
cord-287093-9mertwj7	155	13	may	may	MD
cord-287093-9mertwj7	155	14	involve	involve	VB
cord-287093-9mertwj7	155	15	the	the	DT
cord-287093-9mertwj7	155	16	Golgi	Golgi	NNP
cord-287093-9mertwj7	155	17	,	,	,
cord-287093-9mertwj7	155	18	ER	ER	NNP
cord-287093-9mertwj7	155	19	and/or	and/or	CC
cord-287093-9mertwj7	155	20	autophagosomes	autophagosomes	NNP
cord-287093-9mertwj7	155	21	.	.	.
cord-287093-9mertwj7	156	1	Nucleo	nucleo	JJ
cord-287093-9mertwj7	156	2	-	-	HYPH
cord-287093-9mertwj7	156	3	cytoplasmic	cytoplasmic	JJ
cord-287093-9mertwj7	156	4	large	large	JJ
cord-287093-9mertwj7	156	5	DNA	dna	NN
cord-287093-9mertwj7	156	6	viruses	virus	NNS
cord-287093-9mertwj7	156	7	(	(	-LRB-
cord-287093-9mertwj7	156	8	NCLDV	NCLDV	NNP
cord-287093-9mertwj7	156	9	)	)	-RRB-
cord-287093-9mertwj7	156	10	factories	factory	NNS
cord-287093-9mertwj7	156	11	are	be	VBP
cord-287093-9mertwj7	156	12	formed	form	VBN
cord-287093-9mertwj7	156	13	after	after	IN
cord-287093-9mertwj7	156	14	microtubule	microtubule	NN
cord-287093-9mertwj7	156	15	-	-	HYPH
cord-287093-9mertwj7	156	16	mediated	mediate	VBN
cord-287093-9mertwj7	156	17	delivery	delivery	NN
cord-287093-9mertwj7	156	18	of	of	IN
cord-287093-9mertwj7	156	19	incoming	incoming	JJ
cord-287093-9mertwj7	156	20	viruses	virus	NNS
cord-287093-9mertwj7	156	21	to	to	IN
cord-287093-9mertwj7	156	22	the	the	DT
cord-287093-9mertwj7	156	23	microtubule	microtubule	JJ
cord-287093-9mertwj7	156	24	organising	organising	NN
cord-287093-9mertwj7	156	25	centre	centre	NN
cord-287093-9mertwj7	156	26	next	next	RB
cord-287093-9mertwj7	156	27	to	to	IN
cord-287093-9mertwj7	156	28	the	the	DT
cord-287093-9mertwj7	156	29	nucleus	nucleus	NN
cord-287093-9mertwj7	156	30	.	.	.
cord-287093-9mertwj7	157	1	Thereafter	thereafter	RB
cord-287093-9mertwj7	157	2	they	-PRON-	PRP
cord-287093-9mertwj7	157	3	recruit	recruit	VBP
cord-287093-9mertwj7	157	4	host	host	NN
cord-287093-9mertwj7	157	5	chaperones	chaperone	NNS
cord-287093-9mertwj7	157	6	,	,	,
cord-287093-9mertwj7	157	7	mitochondria	mitochondrion	NNS
cord-287093-9mertwj7	157	8	and	and	CC
cord-287093-9mertwj7	157	9	intermediate	intermediate	JJ
cord-287093-9mertwj7	157	10	filaments	filament	NNS
cord-287093-9mertwj7	157	11	.	.	.
cord-287093-9mertwj7	158	1	membranes	membrane	NNS
cord-287093-9mertwj7	158	2	house	house	NNP
cord-287093-9mertwj7	159	1	the	the	DT
cord-287093-9mertwj7	159	2	virus	virus	NN
cord-287093-9mertwj7	159	3	replicase	replicase	NN
cord-287093-9mertwj7	159	4	and	and	CC
cord-287093-9mertwj7	159	5	replication	replication	NN
cord-287093-9mertwj7	159	6	may	may	MD
cord-287093-9mertwj7	159	7	occur	occur	VB
cord-287093-9mertwj7	159	8	on	on	IN
cord-287093-9mertwj7	159	9	the	the	DT
cord-287093-9mertwj7	159	10	cytoplasmic	cytoplasmic	JJ
cord-287093-9mertwj7	159	11	face	face	NN
cord-287093-9mertwj7	159	12	of	of	IN
cord-287093-9mertwj7	159	13	the	the	DT
cord-287093-9mertwj7	159	14	ER	ER	NNP
cord-287093-9mertwj7	159	15	rather	rather	RB
cord-287093-9mertwj7	159	16	than	than	IN
cord-287093-9mertwj7	159	17	in	in	IN
cord-287093-9mertwj7	159	18	vesicles	vesicle	NNS
cord-287093-9mertwj7	159	19	[	[	-LRB-
cord-287093-9mertwj7	159	20	5	5	CD
cord-287093-9mertwj7	159	21	]	]	-RRB-
cord-287093-9mertwj7	159	22	.	.	.
cord-287093-9mertwj7	160	1	Parallels	parallel	NNS
cord-287093-9mertwj7	160	2	between	between	IN
cord-287093-9mertwj7	160	3	plant	plant	NN
cord-287093-9mertwj7	160	4	and	and	CC
cord-287093-9mertwj7	160	5	animal	animal	NN
cord-287093-9mertwj7	160	6	picornaviruses	picornavirus	NNS
cord-287093-9mertwj7	160	7	are	be	VBP
cord-287093-9mertwj7	160	8	therefore	therefore	RB
cord-287093-9mertwj7	160	9	difficult	difficult	JJ
cord-287093-9mertwj7	160	10	to	to	TO
cord-287093-9mertwj7	160	11	define	define	VB
cord-287093-9mertwj7	160	12	.	.	.
cord-287093-9mertwj7	161	1	The	the	DT
cord-287093-9mertwj7	161	2	large	large	JJ
cord-287093-9mertwj7	161	3	DNA	dna	NN
cord-287093-9mertwj7	161	4	viruses	virus	NNS
cord-287093-9mertwj7	161	5	of	of	IN
cord-287093-9mertwj7	161	6	animals	animal	NNS
cord-287093-9mertwj7	161	7	such	such	JJ
cord-287093-9mertwj7	161	8	as	as	IN
cord-287093-9mertwj7	161	9	poxviruses	poxvirus	NNS
cord-287093-9mertwj7	161	10	and	and	CC
cord-287093-9mertwj7	161	11	other	other	JJ
cord-287093-9mertwj7	161	12	members	member	NNS
cord-287093-9mertwj7	161	13	of	of	IN
cord-287093-9mertwj7	161	14	the	the	DT
cord-287093-9mertwj7	161	15	NCLDV	NCLDV	NNP
cord-287093-9mertwj7	161	16	generate	generate	VBP
cord-287093-9mertwj7	161	17	perinuclear	perinuclear	NN
cord-287093-9mertwj7	161	18	inclusions	inclusion	NNS
cord-287093-9mertwj7	161	19	called	call	VBN
cord-287093-9mertwj7	161	20	virus	virus	NN
cord-287093-9mertwj7	161	21	factories	factory	NNS
cord-287093-9mertwj7	161	22	that	that	WDT
cord-287093-9mertwj7	161	23	assemble	assemble	VBP
cord-287093-9mertwj7	161	24	at	at	IN
cord-287093-9mertwj7	161	25	the	the	DT
cord-287093-9mertwj7	161	26	MTOC	MTOC	NNP
cord-287093-9mertwj7	161	27	and	and	CC
cord-287093-9mertwj7	161	28	are	be	VBP
cord-287093-9mertwj7	161	29	maintained	maintain	VBN
cord-287093-9mertwj7	161	30	by	by	IN
cord-287093-9mertwj7	161	31	dynein	dynein	JJ
cord-287093-9mertwj7	161	32	microtubule	microtubule	JJ
cord-287093-9mertwj7	161	33	motor	motor	NN
cord-287093-9mertwj7	161	34	proteins	protein	NNS
cord-287093-9mertwj7	161	35	.	.	.
cord-287093-9mertwj7	162	1	Replication	replication	NN
cord-287093-9mertwj7	162	2	complexes	complex	NNS
cord-287093-9mertwj7	162	3	generated	generate	VBN
cord-287093-9mertwj7	162	4	in	in	IN
cord-287093-9mertwj7	162	5	plants	plant	NNS
cord-287093-9mertwj7	162	6	often	often	RB
cord-287093-9mertwj7	162	7	move	move	VBP
cord-287093-9mertwj7	162	8	through	through	IN
cord-287093-9mertwj7	162	9	cells	cell	NNS
cord-287093-9mertwj7	162	10	onboard	onboard	IN
cord-287093-9mertwj7	162	11	microtubule	microtubule	JJ
cord-287093-9mertwj7	162	12	motor	motor	NN
cord-287093-9mertwj7	162	13	proteins	protein	NNS
cord-287093-9mertwj7	162	14	(	(	-LRB-
cord-287093-9mertwj7	162	15	Figure	figure	NN
cord-287093-9mertwj7	162	16	2	2	CD
cord-287093-9mertwj7	162	17	)	)	-RRB-
cord-287093-9mertwj7	162	18	,	,	,
cord-287093-9mertwj7	162	19	but	but	CC
cord-287093-9mertwj7	162	20	perinuclear	perinuclear	NN
cord-287093-9mertwj7	162	21	inclusions	inclusion	NNS
cord-287093-9mertwj7	162	22	are	be	VBP
cord-287093-9mertwj7	162	23	not	not	RB
cord-287093-9mertwj7	162	24	found	find	VBN
cord-287093-9mertwj7	162	25	for	for	IN
cord-287093-9mertwj7	162	26	plant	plant	NN
cord-287093-9mertwj7	162	27	viruses	virus	NNS
cord-287093-9mertwj7	162	28	.	.	.
cord-287093-9mertwj7	163	1	As	as	IN
cord-287093-9mertwj7	163	2	pointed	point	VBN
cord-287093-9mertwj7	163	3	out	out	RP
cord-287093-9mertwj7	163	4	in	in	IN
cord-287093-9mertwj7	163	5	the	the	DT
cord-287093-9mertwj7	163	6	accompanying	accompany	VBG
cord-287093-9mertwj7	163	7	review	review	NN
cord-287093-9mertwj7	163	8	by	by	IN
cord-287093-9mertwj7	163	9	Jeanmarie	Jeanmarie	NNP
cord-287093-9mertwj7	163	10	Verchot	Verchot	NNP
cord-287093-9mertwj7	163	11	,	,	,
cord-287093-9mertwj7	163	12	plants	plant	NNS
cord-287093-9mertwj7	163	13	lack	lack	VBP
cord-287093-9mertwj7	163	14	a	a	DT
cord-287093-9mertwj7	163	15	MTOC	MTOC	NNP
cord-287093-9mertwj7	163	16	to	to	TO
cord-287093-9mertwj7	163	17	concentrate	concentrate	VB
cord-287093-9mertwj7	163	18	motor	motor	NN
cord-287093-9mertwj7	163	19	cargoes	cargo	NNS
cord-287093-9mertwj7	163	20	,	,	,
cord-287093-9mertwj7	163	21	and	and	CC
cord-287093-9mertwj7	163	22	replication	replication	NN
cord-287093-9mertwj7	163	23	sites	site	NNS
cord-287093-9mertwj7	163	24	are	be	VBP
cord-287093-9mertwj7	163	25	therefore	therefore	RB
cord-287093-9mertwj7	163	26	dispersed	disperse	VBN
cord-287093-9mertwj7	163	27	throughout	throughout	IN
cord-287093-9mertwj7	163	28	the	the	DT
cord-287093-9mertwj7	163	29	cell	cell	NN
cord-287093-9mertwj7	163	30	.	.	.
cord-287093-9mertwj7	164	1	Origins	origin	NNS
cord-287093-9mertwj7	164	2	of	of	IN
cord-287093-9mertwj7	164	3	membrane	membrane	NN
cord-287093-9mertwj7	164	4	vesicles	vesicle	NNS
cord-287093-9mertwj7	164	5	generated	generate	VBN
cord-287093-9mertwj7	164	6	during	during	IN
cord-287093-9mertwj7	164	7	replication	replication	NN
cord-287093-9mertwj7	164	8	of	of	IN
cord-287093-9mertwj7	164	9	positive	positive	JJ
cord-287093-9mertwj7	164	10	-	-	HYPH
cord-287093-9mertwj7	164	11	strand	strand	NN
cord-287093-9mertwj7	164	12	RNA	RNA	NNP
cord-287093-9mertwj7	164	13	viruses	virus	NNS
cord-287093-9mertwj7	165	1	Organelle	Organelle	NNP
cord-287093-9mertwj7	165	2	-	-	HYPH
cord-287093-9mertwj7	165	3	like	like	JJ
cord-287093-9mertwj7	165	4	membrane	membrane	NN
cord-287093-9mertwj7	165	5	compartmentalization	compartmentalization	NN
cord-287093-9mertwj7	165	6	of	of	IN
cord-287093-9mertwj7	165	7	positive	positive	JJ
cord-287093-9mertwj7	165	8	-	-	HYPH
cord-287093-9mertwj7	165	9	strand	strand	NN
cord-287093-9mertwj7	165	10	RNA	RNA	NNP
cord-287093-9mertwj7	165	11	virus	virus	NN
cord-287093-9mertwj7	165	12	replication	replication	NN
cord-287093-9mertwj7	165	13	factories	factory	NNS
cord-287093-9mertwj7	165	14	Cytoplasmic	Cytoplasmic	NNP
cord-287093-9mertwj7	165	15	viral	viral	JJ
cord-287093-9mertwj7	165	16	replication	replication	NN
cord-287093-9mertwj7	165	17	complexes	complex	NNS
cord-287093-9mertwj7	165	18	Cellular	cellular	JJ
cord-287093-9mertwj7	165	19	origin	origin	NN
cord-287093-9mertwj7	165	20	and	and	CC
cord-287093-9mertwj7	165	21	ultrastructure	ultrastructure	NN
cord-287093-9mertwj7	165	22	of	of	IN
cord-287093-9mertwj7	165	23	membranes	membrane	NNS
cord-287093-9mertwj7	165	24	induced	induce	VBN
cord-287093-9mertwj7	165	25	during	during	IN
cord-287093-9mertwj7	165	26	poliovirus	poliovirus	NN
cord-287093-9mertwj7	165	27	infection	infection	NN
cord-287093-9mertwj7	165	28	Formation	formation	NN
cord-287093-9mertwj7	165	29	of	of	IN
cord-287093-9mertwj7	165	30	the	the	DT
cord-287093-9mertwj7	165	31	poliovirus	poliovirus	NN
cord-287093-9mertwj7	165	32	replication	replication	NN
cord-287093-9mertwj7	165	33	complex	complex	NN
cord-287093-9mertwj7	165	34	requires	require	VBZ
cord-287093-9mertwj7	165	35	coupled	couple	VBN
cord-287093-9mertwj7	165	36	viral	viral	JJ
cord-287093-9mertwj7	165	37	translation	translation	NN
cord-287093-9mertwj7	165	38	,	,	,
cord-287093-9mertwj7	165	39	vesicle	vesicle	NN
cord-287093-9mertwj7	165	40	production	production	NN
cord-287093-9mertwj7	165	41	,	,	,
cord-287093-9mertwj7	165	42	and	and	CC
cord-287093-9mertwj7	165	43	viral	viral	JJ
cord-287093-9mertwj7	165	44	RNA	RNA	NNP
cord-287093-9mertwj7	165	45	synthesis	synthesis	NN
cord-287093-9mertwj7	165	46	Modulation	modulation	NN
cord-287093-9mertwj7	165	47	of	of	IN
cord-287093-9mertwj7	165	48	membrane	membrane	NN
cord-287093-9mertwj7	165	49	traffic	traffic	NN
cord-287093-9mertwj7	165	50	between	between	IN
cord-287093-9mertwj7	165	51	endoplasmic	endoplasmic	NN
cord-287093-9mertwj7	165	52	reticulum	reticulum	NN
cord-287093-9mertwj7	165	53	,	,	,
cord-287093-9mertwj7	165	54	ERGIC	ERGIC	NNP
cord-287093-9mertwj7	165	55	and	and	CC
cord-287093-9mertwj7	165	56	Golgi	Golgi	NNP
cord-287093-9mertwj7	165	57	to	to	TO
cord-287093-9mertwj7	165	58	generate	generate	VB
cord-287093-9mertwj7	165	59	compartments	compartment	NNS
cord-287093-9mertwj7	165	60	for	for	IN
cord-287093-9mertwj7	165	61	the	the	DT
cord-287093-9mertwj7	165	62	replication	replication	NN
cord-287093-9mertwj7	165	63	of	of	IN
cord-287093-9mertwj7	165	64	bacteria	bacteria	NNS
cord-287093-9mertwj7	165	65	and	and	CC
cord-287093-9mertwj7	165	66	viruses	virus	NNS
cord-287093-9mertwj7	165	67	Three	three	CD
cord-287093-9mertwj7	165	68	-	-	HYPH
cord-287093-9mertwj7	165	69	dimensional	dimensional	JJ
cord-287093-9mertwj7	165	70	structure	structure	NN
cord-287093-9mertwj7	165	71	of	of	IN
cord-287093-9mertwj7	165	72	Rubella	Rubella	NNP
cord-287093-9mertwj7	165	73	virus	virus	NN
cord-287093-9mertwj7	165	74	factories	factory	NNS
cord-287093-9mertwj7	165	75	Flock	Flock	NNP
cord-287093-9mertwj7	165	76	house	house	NN
cord-287093-9mertwj7	165	77	virus	virus	NN
cord-287093-9mertwj7	165	78	RNA	RNA	NNP
cord-287093-9mertwj7	165	79	replicates	replicate	VBZ
cord-287093-9mertwj7	165	80	on	on	IN
cord-287093-9mertwj7	165	81	outer	outer	JJ
cord-287093-9mertwj7	165	82	mitochondrial	mitochondrial	JJ
cord-287093-9mertwj7	165	83	membranes	membrane	NNS
cord-287093-9mertwj7	165	84	in	in	IN
cord-287093-9mertwj7	165	85	Drosophila	Drosophila	NNP
cord-287093-9mertwj7	165	86	cells	cell	NNS
cord-287093-9mertwj7	166	1	EM	EM	NNP
cord-287093-9mertwj7	166	2	tomography	tomography	NN
cord-287093-9mertwj7	166	3	provides	provide	VBZ
cord-287093-9mertwj7	166	4	the	the	DT
cord-287093-9mertwj7	166	5	first	first	JJ
cord-287093-9mertwj7	166	6	3D	3d	JJ
cord-287093-9mertwj7	166	7	reconstructions	reconstruction	NNS
cord-287093-9mertwj7	166	8	of	of	IN
cord-287093-9mertwj7	166	9	membrane	membrane	NN
cord-287093-9mertwj7	166	10	invaginations	invagination	NNS
cord-287093-9mertwj7	166	11	housing	house	VBG
cord-287093-9mertwj7	166	12	the	the	DT
cord-287093-9mertwj7	166	13	replication	replication	NN
cord-287093-9mertwj7	166	14	complex	complex	NN
cord-287093-9mertwj7	166	15	of	of	IN
cord-287093-9mertwj7	166	16	(	(	-LRB-
cord-287093-9mertwj7	166	17	+	+	CC
cord-287093-9mertwj7	167	1	)	)	-RRB-
cord-287093-9mertwj7	167	2	strand	strand	NN
cord-287093-9mertwj7	167	3	RNA	RNA	NNP
cord-287093-9mertwj7	167	4	virus	virus	NN
cord-287093-9mertwj7	167	5	Composition	composition	NN
cord-287093-9mertwj7	167	6	and	and	CC
cord-287093-9mertwj7	167	7	three	three	CD
cord-287093-9mertwj7	167	8	-	-	HYPH
cord-287093-9mertwj7	167	9	dimensional	dimensional	JJ
cord-287093-9mertwj7	167	10	architecture	architecture	NN
cord-287093-9mertwj7	167	11	of	of	IN
cord-287093-9mertwj7	167	12	the	the	DT
cord-287093-9mertwj7	167	13	dengue	dengue	NN
cord-287093-9mertwj7	167	14	virus	virus	NN
cord-287093-9mertwj7	167	15	replication	replication	NN
cord-287093-9mertwj7	167	16	and	and	CC
cord-287093-9mertwj7	167	17	assembly	assembly	NN
cord-287093-9mertwj7	167	18	sites	site	NNS
cord-287093-9mertwj7	167	19	EM	EM	NNP
cord-287093-9mertwj7	167	20	tomography	tomography	NN
cord-287093-9mertwj7	167	21	provides	provide	VBZ
cord-287093-9mertwj7	167	22	a	a	DT
cord-287093-9mertwj7	167	23	3D	3d	JJ
cord-287093-9mertwj7	167	24	reconstruction	reconstruction	NN
cord-287093-9mertwj7	167	25	of	of	IN
cord-287093-9mertwj7	167	26	membrane	membrane	NN
cord-287093-9mertwj7	167	27	rearrangments	rearrangment	NNS
cord-287093-9mertwj7	167	28	induced	induce	VBN
cord-287093-9mertwj7	167	29	by	by	IN
cord-287093-9mertwj7	167	30	dengue	dengue	NN
cord-287093-9mertwj7	167	31	virus	virus	NN
cord-287093-9mertwj7	167	32	.	.	.
cord-287093-9mertwj7	168	1	The	the	DT
cord-287093-9mertwj7	168	2	vesicles	vesicle	NNS
cord-287093-9mertwj7	168	3	are	be	VBP
cord-287093-9mertwj7	168	4	connected	connect	VBN
cord-287093-9mertwj7	168	5	to	to	IN
cord-287093-9mertwj7	168	6	a	a	DT
cord-287093-9mertwj7	168	7	continuous	continuous	JJ
cord-287093-9mertwj7	168	8	network	network	NN
cord-287093-9mertwj7	168	9	of	of	IN
cord-287093-9mertwj7	168	10	endoplasmic	endoplasmic	NN
cord-287093-9mertwj7	168	11	reticulum	reticulum	NN
cord-287093-9mertwj7	168	12	and	and	CC
cord-287093-9mertwj7	168	13	a	a	DT
cord-287093-9mertwj7	168	14	pore	pore	NN
cord-287093-9mertwj7	168	15	connects	connect	VBZ
cord-287093-9mertwj7	168	16	the	the	DT
cord-287093-9mertwj7	168	17	vesicles	vesicle	NNS
cord-287093-9mertwj7	168	18	to	to	IN
cord-287093-9mertwj7	168	19	the	the	DT
cord-287093-9mertwj7	168	20	cytoplasm	cytoplasm	NN
cord-287093-9mertwj7	168	21	.	.	.
cord-287093-9mertwj7	169	1	Some	some	DT
cord-287093-9mertwj7	169	2	pores	pore	NNS
cord-287093-9mertwj7	169	3	lie	lie	VBP
cord-287093-9mertwj7	169	4	opposites	opposite	NNS
cord-287093-9mertwj7	169	5	sites	site	NNS
cord-287093-9mertwj7	169	6	of	of	IN
cord-287093-9mertwj7	169	7	virus	virus	NN
cord-287093-9mertwj7	169	8	envelopment	envelopment	NN
cord-287093-9mertwj7	169	9	SARS	SARS	NNP
cord-287093-9mertwj7	169	10	-	-	HYPH
cord-287093-9mertwj7	169	11	coronavirus	coronavirus	NN
cord-287093-9mertwj7	169	12	replication	replication	NN
cord-287093-9mertwj7	169	13	is	be	VBZ
cord-287093-9mertwj7	169	14	supported	support	VBN
cord-287093-9mertwj7	169	15	by	by	IN
cord-287093-9mertwj7	169	16	a	a	DT
cord-287093-9mertwj7	169	17	reticulovesicular	reticulovesicular	JJ
cord-287093-9mertwj7	169	18	network	network	NN
cord-287093-9mertwj7	169	19	of	of	IN
cord-287093-9mertwj7	169	20	modified	modify	VBN
cord-287093-9mertwj7	169	21	endoplasmic	endoplasmic	NN
cord-287093-9mertwj7	169	22	reticulum	reticulum	NN
cord-287093-9mertwj7	169	23	EM	EM	NNP
cord-287093-9mertwj7	169	24	tomography	tomography	NN
cord-287093-9mertwj7	170	1	provides	provide	VBZ
cord-287093-9mertwj7	170	2	a	a	DT
cord-287093-9mertwj7	170	3	3D	3d	JJ
cord-287093-9mertwj7	170	4	reconstruction	reconstruction	NN
cord-287093-9mertwj7	170	5	of	of	IN
cord-287093-9mertwj7	170	6	membrane	membrane	NN
cord-287093-9mertwj7	170	7	rearrangemnts	rearrangemnt	NNS
cord-287093-9mertwj7	170	8	induced	induce	VBN
cord-287093-9mertwj7	170	9	by	by	IN
cord-287093-9mertwj7	170	10	SARS	SARS	NNP
cord-287093-9mertwj7	170	11	-	-	HYPH
cord-287093-9mertwj7	170	12	coronavirus	coronavirus	NN
cord-287093-9mertwj7	170	13	.	.	.
cord-287093-9mertwj7	171	1	The	the	DT
cord-287093-9mertwj7	171	2	double	double	JJ
cord-287093-9mertwj7	171	3	-	-	HYPH
cord-287093-9mertwj7	171	4	membraned	membraned	JJ
cord-287093-9mertwj7	171	5	vesicles	vesicle	NNS
cord-287093-9mertwj7	171	6	are	be	VBP
cord-287093-9mertwj7	171	7	connected	connect	VBN
cord-287093-9mertwj7	171	8	to	to	IN
cord-287093-9mertwj7	171	9	a	a	DT
cord-287093-9mertwj7	171	10	continuous	continuous	JJ
cord-287093-9mertwj7	171	11	network	network	NN
cord-287093-9mertwj7	171	12	of	of	IN
cord-287093-9mertwj7	171	13	endoplasmic	endoplasmic	NN
cord-287093-9mertwj7	171	14	reticulum	reticulum	NN
cord-287093-9mertwj7	171	15	Poliovirus	Poliovirus	NNP
cord-287093-9mertwj7	171	16	infection	infection	NN
cord-287093-9mertwj7	171	17	blocks	block	VBZ
cord-287093-9mertwj7	171	18	ERGIC	ergic	NN
cord-287093-9mertwj7	171	19	-	-	HYPH
cord-287093-9mertwj7	171	20	to	to	IN
cord-287093-9mertwj7	171	21	-	-	HYPH
cord-287093-9mertwj7	171	22	Golgi	golgi	NN
cord-287093-9mertwj7	171	23	trafficking	trafficking	NN
cord-287093-9mertwj7	171	24	and	and	CC
cord-287093-9mertwj7	171	25	induces	induce	VBZ
cord-287093-9mertwj7	171	26	microtubule	microtubule	NN
cord-287093-9mertwj7	171	27	-	-	HYPH
cord-287093-9mertwj7	171	28	dependent	dependent	JJ
cord-287093-9mertwj7	171	29	disruption	disruption	NN
cord-287093-9mertwj7	171	30	of	of	IN
cord-287093-9mertwj7	171	31	the	the	DT
cord-287093-9mertwj7	171	32	Golgi	Golgi	NNP
cord-287093-9mertwj7	171	33	complex	complex	JJ
cord-287093-9mertwj7	171	34	Subversion	subversion	NN
cord-287093-9mertwj7	171	35	of	of	IN
cord-287093-9mertwj7	171	36	cellular	cellular	JJ
cord-287093-9mertwj7	171	37	autophagosomal	autophagosomal	NN
cord-287093-9mertwj7	171	38	machinery	machinery	NN
cord-287093-9mertwj7	171	39	by	by	IN
cord-287093-9mertwj7	171	40	RNA	RNA	NNP
cord-287093-9mertwj7	171	41	viruses	virus	NNS
cord-287093-9mertwj7	172	1	The	the	DT
cord-287093-9mertwj7	172	2	ultrastructure	ultrastructure	NN
cord-287093-9mertwj7	172	3	of	of	IN
cord-287093-9mertwj7	172	4	the	the	DT
cord-287093-9mertwj7	172	5	developing	develop	VBG
cord-287093-9mertwj7	172	6	replication	replication	NN
cord-287093-9mertwj7	172	7	site	site	NN
cord-287093-9mertwj7	172	8	in	in	IN
cord-287093-9mertwj7	172	9	foot	foot	NN
cord-287093-9mertwj7	172	10	-	-	HYPH
cord-287093-9mertwj7	172	11	andmouth	andmouth	NNP
cord-287093-9mertwj7	172	12	disease	disease	NN
cord-287093-9mertwj7	172	13	virus	virus	NN
cord-287093-9mertwj7	172	14	-	-	HYPH
cord-287093-9mertwj7	172	15	infected	infect	VBN
cord-287093-9mertwj7	172	16	BHK-38	BHK-38	NNP
cord-287093-9mertwj7	172	17	cells	cell	NNS
cord-287093-9mertwj7	172	18	Fragmentation	fragmentation	NN
cord-287093-9mertwj7	172	19	of	of	IN
cord-287093-9mertwj7	172	20	the	the	DT
cord-287093-9mertwj7	172	21	Golgi	Golgi	NNP
cord-287093-9mertwj7	172	22	apparatus	apparatus	NN
cord-287093-9mertwj7	172	23	provides	provide	VBZ
cord-287093-9mertwj7	172	24	replication	replication	NN
cord-287093-9mertwj7	172	25	membranes	membrane	NNS
cord-287093-9mertwj7	172	26	for	for	IN
cord-287093-9mertwj7	172	27	human	human	JJ
cord-287093-9mertwj7	172	28	rhinovirus	rhinovirus	NN
cord-287093-9mertwj7	172	29	1A	1a	NN
cord-287093-9mertwj7	172	30	Remodeling	remodel	VBG
cord-287093-9mertwj7	172	31	the	the	DT
cord-287093-9mertwj7	172	32	endoplasmic	endoplasmic	NN
cord-287093-9mertwj7	172	33	reticulum	reticulum	NN
cord-287093-9mertwj7	172	34	by	by	IN
cord-287093-9mertwj7	172	35	poliovirus	poliovirus	NN
cord-287093-9mertwj7	172	36	infection	infection	NN
cord-287093-9mertwj7	172	37	and	and	CC
cord-287093-9mertwj7	172	38	by	by	IN
cord-287093-9mertwj7	172	39	individual	individual	JJ
cord-287093-9mertwj7	172	40	viral	viral	JJ
cord-287093-9mertwj7	172	41	proteins	protein	NNS
cord-287093-9mertwj7	172	42	:	:	:
cord-287093-9mertwj7	172	43	an	an	DT
cord-287093-9mertwj7	172	44	autophagy	autophagy	NN
cord-287093-9mertwj7	172	45	-	-	HYPH
cord-287093-9mertwj7	172	46	like	like	JJ
cord-287093-9mertwj7	172	47	origin	origin	NN
cord-287093-9mertwj7	172	48	for	for	IN
cord-287093-9mertwj7	172	49	virusinduced	virusinduce	VBN
cord-287093-9mertwj7	172	50	vesicles	vesicle	NNS
cord-287093-9mertwj7	172	51	Synthesis	Synthesis	NNP
cord-287093-9mertwj7	172	52	of	of	IN
cord-287093-9mertwj7	173	1	Semliki	Semliki	NNP
cord-287093-9mertwj7	173	2	Forest	Forest	NNP
cord-287093-9mertwj7	173	3	virus	virus	NN
cord-287093-9mertwj7	173	4	RNA	RNA	NNP
cord-287093-9mertwj7	173	5	requires	require	VBZ
cord-287093-9mertwj7	173	6	continuous	continuous	JJ
cord-287093-9mertwj7	173	7	lipid	lipid	NN
cord-287093-9mertwj7	173	8	synthesis	synthesis	NN
cord-287093-9mertwj7	174	1	Complementary	complementary	JJ
cord-287093-9mertwj7	174	2	transcriptomic	transcriptomic	NNP
cord-287093-9mertwj7	174	3	,	,	,
cord-287093-9mertwj7	174	4	lipidomic	lipidomic	NNP
cord-287093-9mertwj7	174	5	,	,	,
cord-287093-9mertwj7	174	6	and	and	CC
cord-287093-9mertwj7	174	7	targeted	target	VBD
cord-287093-9mertwj7	174	8	functional	functional	JJ
cord-287093-9mertwj7	174	9	genetic	genetic	JJ
cord-287093-9mertwj7	174	10	analyses	analysis	NNS
cord-287093-9mertwj7	174	11	in	in	IN
cord-287093-9mertwj7	174	12	cultured	cultured	JJ
cord-287093-9mertwj7	174	13	Drosophila	Drosophila	NNP
cord-287093-9mertwj7	174	14	cells	cell	NNS
cord-287093-9mertwj7	174	15	highlight	highlight	VBP
cord-287093-9mertwj7	174	16	the	the	DT
cord-287093-9mertwj7	174	17	role	role	NN
cord-287093-9mertwj7	174	18	of	of	IN
cord-287093-9mertwj7	174	19	glycerophospholipid	glycerophospholipid	NNP
cord-287093-9mertwj7	174	20	metabolism	metabolism	NN
cord-287093-9mertwj7	174	21	in	in	IN
cord-287093-9mertwj7	174	22	Flock	Flock	NNP
cord-287093-9mertwj7	174	23	house	house	NNP
cord-287093-9mertwj7	174	24	virus	virus	NN
cord-287093-9mertwj7	174	25	RNA	RNA	NNP
cord-287093-9mertwj7	174	26	replication	replication	NN
cord-287093-9mertwj7	174	27	Hepatitis	Hepatitis	NNP
cord-287093-9mertwj7	174	28	C	C	NNP
cord-287093-9mertwj7	174	29	virus	virus	NN
cord-287093-9mertwj7	174	30	RNA	rna	NN
cord-287093-9mertwj7	174	31	replication	replication	NN
cord-287093-9mertwj7	174	32	is	be	VBZ
cord-287093-9mertwj7	174	33	regulated	regulate	VBN
cord-287093-9mertwj7	174	34	by	by	IN
cord-287093-9mertwj7	174	35	host	host	NN
cord-287093-9mertwj7	174	36	geranylgeranylation	geranylgeranylation	NN
cord-287093-9mertwj7	174	37	and	and	CC
cord-287093-9mertwj7	174	38	fatty	fatty	JJ
cord-287093-9mertwj7	174	39	acids	acid	NNS
cord-287093-9mertwj7	174	40	Phospholipid	Phospholipid	NNP
cord-287093-9mertwj7	174	41	biosynthesis	biosynthesis	NN
cord-287093-9mertwj7	174	42	and	and	CC
cord-287093-9mertwj7	174	43	poliovirus	poliovirus	NN
cord-287093-9mertwj7	174	44	genome	genome	NN
cord-287093-9mertwj7	174	45	replication	replication	NN
cord-287093-9mertwj7	174	46	,	,	,
cord-287093-9mertwj7	174	47	two	two	CD
cord-287093-9mertwj7	174	48	coupled	couple	VBN
cord-287093-9mertwj7	174	49	phenomena	phenomenon	NNS
cord-287093-9mertwj7	175	1	The	the	DT
cord-287093-9mertwj7	175	2	human	human	JJ
cord-287093-9mertwj7	175	3	fatty	fatty	JJ
cord-287093-9mertwj7	175	4	acid	acid	NN
cord-287093-9mertwj7	175	5	synthase	synthase	NN
cord-287093-9mertwj7	175	6	:	:	:
cord-287093-9mertwj7	175	7	a	a	DT
cord-287093-9mertwj7	175	8	new	new	JJ
cord-287093-9mertwj7	175	9	therapeutic	therapeutic	JJ
cord-287093-9mertwj7	175	10	target	target	NN
cord-287093-9mertwj7	175	11	for	for	IN
cord-287093-9mertwj7	175	12	coxsackievirus	coxsackievirus	NNP
cord-287093-9mertwj7	175	13	B3-induced	b3-induce	VBN
cord-287093-9mertwj7	175	14	diseases	disease	NNS
cord-287093-9mertwj7	175	15	?	?	.
cord-287093-9mertwj7	176	1	Non	non	JJ
cord-287093-9mertwj7	176	2	-	-	JJ
cord-287093-9mertwj7	176	3	structural	structural	JJ
cord-287093-9mertwj7	176	4	proteins	protein	NNS
cord-287093-9mertwj7	176	5	2	2	CD
cord-287093-9mertwj7	176	6	and	and	CC
cord-287093-9mertwj7	176	7	3	3	CD
cord-287093-9mertwj7	176	8	interact	interact	VBP
cord-287093-9mertwj7	176	9	to	to	TO
cord-287093-9mertwj7	176	10	modify	modify	VB
cord-287093-9mertwj7	176	11	host	host	NN
cord-287093-9mertwj7	176	12	cell	cell	NN
cord-287093-9mertwj7	176	13	membranes	membrane	NNS
cord-287093-9mertwj7	176	14	during	during	IN
cord-287093-9mertwj7	176	15	the	the	DT
cord-287093-9mertwj7	176	16	formation	formation	NN
cord-287093-9mertwj7	176	17	of	of	IN
cord-287093-9mertwj7	176	18	the	the	DT
cord-287093-9mertwj7	176	19	arterivirus	arterivirus	NNP
cord-287093-9mertwj7	176	20	replication	replication	NN
cord-287093-9mertwj7	176	21	complex	complex	NNP
cord-287093-9mertwj7	176	22	Formation	Formation	NNP
cord-287093-9mertwj7	176	23	of	of	IN
cord-287093-9mertwj7	176	24	the	the	DT
cord-287093-9mertwj7	176	25	arterivirus	arterivirus	NNP
cord-287093-9mertwj7	176	26	replication	replication	NN
cord-287093-9mertwj7	176	27	/	/	SYM
cord-287093-9mertwj7	176	28	transcription	transcription	NN
cord-287093-9mertwj7	176	29	complex	complex	NN
cord-287093-9mertwj7	176	30	:	:	:
cord-287093-9mertwj7	177	1	a	a	DT
cord-287093-9mertwj7	177	2	key	key	JJ
cord-287093-9mertwj7	177	3	role	role	NN
cord-287093-9mertwj7	177	4	for	for	IN
cord-287093-9mertwj7	177	5	nonstructural	nonstructural	JJ
cord-287093-9mertwj7	177	6	protein	protein	NNP
cord-287093-9mertwj7	177	7	3	3	CD
cord-287093-9mertwj7	177	8	in	in	IN
cord-287093-9mertwj7	177	9	the	the	DT
cord-287093-9mertwj7	177	10	remodeling	remodeling	NN
cord-287093-9mertwj7	177	11	of	of	IN
cord-287093-9mertwj7	177	12	intracellular	intracellular	JJ
cord-287093-9mertwj7	177	13	membranes	membrane	NNS
cord-287093-9mertwj7	177	14	Mouse	Mouse	NNP
cord-287093-9mertwj7	177	15	hepatitis	hepatitis	NN
cord-287093-9mertwj7	177	16	coronavirus	coronavirus	NN
cord-287093-9mertwj7	177	17	RNA	RNA	NNP
cord-287093-9mertwj7	177	18	replication	replication	NN
cord-287093-9mertwj7	177	19	depends	depend	VBZ
cord-287093-9mertwj7	177	20	on	on	IN
cord-287093-9mertwj7	177	21	GBF1-mediated	GBF1-mediated	NNP
cord-287093-9mertwj7	177	22	ARF1	ARF1	NNP
cord-287093-9mertwj7	177	23	activation	activation	NN
cord-287093-9mertwj7	177	24	Viral	viral	JJ
cord-287093-9mertwj7	177	25	reorganization	reorganization	NN
cord-287093-9mertwj7	177	26	of	of	IN
cord-287093-9mertwj7	177	27	the	the	DT
cord-287093-9mertwj7	177	28	secretory	secretory	JJ
cord-287093-9mertwj7	177	29	pathway	pathway	NN
cord-287093-9mertwj7	177	30	generates	generate	VBZ
cord-287093-9mertwj7	177	31	distinct	distinct	JJ
cord-287093-9mertwj7	177	32	organelles	organelle	NNS
cord-287093-9mertwj7	177	33	for	for	IN
cord-287093-9mertwj7	177	34	RNA	RNA	NNP
cord-287093-9mertwj7	177	35	replication	replication	NN
cord-287093-9mertwj7	177	36	Studies	Studies	NNPS
cord-287093-9mertwj7	177	37	on	on	IN
cord-287093-9mertwj7	177	38	enterovirus	enterovirus	NN
cord-287093-9mertwj7	177	39	replication	replication	NN
cord-287093-9mertwj7	177	40	show	show	VBP
cord-287093-9mertwj7	177	41	that	that	IN
cord-287093-9mertwj7	177	42	the	the	DT
cord-287093-9mertwj7	177	43	3A	3a	CD
cord-287093-9mertwj7	177	44	nonstructural	nonstructural	NNP
cord-287093-9mertwj7	177	45	proten	proten	NNP
cord-287093-9mertwj7	177	46	modulates	modulate	VBZ
cord-287093-9mertwj7	177	47	the	the	DT
cord-287093-9mertwj7	177	48	activity	activity	NN
cord-287093-9mertwj7	177	49	of	of	IN
cord-287093-9mertwj7	177	50	the	the	DT
cord-287093-9mertwj7	177	51	Arf1	Arf1	NNP
cord-287093-9mertwj7	177	52	GTPase	GTPase	NNP
cord-287093-9mertwj7	177	53	and	and	CC
cord-287093-9mertwj7	177	54	its	-PRON-	PRP$
cord-287093-9mertwj7	177	55	guanine	guanine	NN
cord-287093-9mertwj7	177	56	nucleotide	nucleotide	JJ
cord-287093-9mertwj7	177	57	exchange	exchange	NN
cord-287093-9mertwj7	177	58	factor	factor	NN
cord-287093-9mertwj7	177	59	GBF1	GBF1	NNP
cord-287093-9mertwj7	177	60	.	.	.
cord-287093-9mertwj7	178	1	This	this	DT
cord-287093-9mertwj7	178	2	increases	increase	VBZ
cord-287093-9mertwj7	178	3	recrutment	recrutment	NN
cord-287093-9mertwj7	178	4	of	of	IN
cord-287093-9mertwj7	178	5	Srf1	Srf1	NNP
cord-287093-9mertwj7	178	6	effector	effector	NN
cord-287093-9mertwj7	178	7	protein	protein	NN
cord-287093-9mertwj7	178	8	,	,	,
cord-287093-9mertwj7	178	9	phosphatidylinositol-4-kinase	phosphatidylinositol-4-kinase	NN
cord-287093-9mertwj7	178	10	-	-	HYPH
cord-287093-9mertwj7	178	11	IIIb	IIIb	NNP
cord-287093-9mertwj7	178	12	(	(	-LRB-
cord-287093-9mertwj7	178	13	PI4KIIIb	PI4KIIIb	NNP
cord-287093-9mertwj7	178	14	)	)	-RRB-
cord-287093-9mertwj7	178	15	to	to	IN
cord-287093-9mertwj7	178	16	the	the	DT
cord-287093-9mertwj7	178	17	cytoplsmic	cytoplsmic	JJ
cord-287093-9mertwj7	178	18	face	face	NN
cord-287093-9mertwj7	178	19	of	of	IN
cord-287093-9mertwj7	178	20	the	the	DT
cord-287093-9mertwj7	178	21	endoplasmic	endoplasmic	NN
cord-287093-9mertwj7	178	22	reticulum	reticulum	NN
cord-287093-9mertwj7	178	23	.	.	.
cord-287093-9mertwj7	179	1	Formation	formation	NN
cord-287093-9mertwj7	179	2	of	of	IN
cord-287093-9mertwj7	179	3	phosphatidylinositol-4-phosphate	phosphatidylinositol-4-phosphate	NNP
cord-287093-9mertwj7	179	4	provides	provide	VBZ
cord-287093-9mertwj7	179	5	a	a	DT
cord-287093-9mertwj7	179	6	binding	binding	JJ
cord-287093-9mertwj7	179	7	site	site	NN
cord-287093-9mertwj7	179	8	for	for	IN
cord-287093-9mertwj7	179	9	the	the	DT
cord-287093-9mertwj7	179	10	viral	viral	JJ
cord-287093-9mertwj7	179	11	RNA	RNA	NNP
cord-287093-9mertwj7	179	12	polymerase	polymerase	NN
cord-287093-9mertwj7	179	13	and	and	CC
cord-287093-9mertwj7	179	14	inhibition	inhibition	NN
cord-287093-9mertwj7	179	15	of	of	IN
cord-287093-9mertwj7	179	16	the	the	DT
cord-287093-9mertwj7	179	17	PI4KIIIb	PI4KIIIb	NNP
cord-287093-9mertwj7	179	18	kinase	kinase	NN
cord-287093-9mertwj7	180	1	slows	slow	VBZ
cord-287093-9mertwj7	180	2	replication	replication	NN
cord-287093-9mertwj7	180	3	Inhibition	inhibition	NN
cord-287093-9mertwj7	180	4	of	of	IN
cord-287093-9mertwj7	180	5	cellular	cellular	JJ
cord-287093-9mertwj7	180	6	protein	protein	NN
cord-287093-9mertwj7	180	7	secretion	secretion	NN
cord-287093-9mertwj7	180	8	by	by	IN
cord-287093-9mertwj7	180	9	picornaviral	picornaviral	NNP
cord-287093-9mertwj7	180	10	3A	3A	NNP
cord-287093-9mertwj7	180	11	proteins	protein	VBZ
cord-287093-9mertwj7	180	12	Differential	Differential	NNP
cord-287093-9mertwj7	180	13	requirements	requirement	NNS
cord-287093-9mertwj7	180	14	for	for	IN
cord-287093-9mertwj7	180	15	COPI	COPI	NNP
cord-287093-9mertwj7	180	16	coats	coat	NNS
cord-287093-9mertwj7	180	17	in	in	IN
cord-287093-9mertwj7	180	18	formation	formation	NN
cord-287093-9mertwj7	180	19	of	of	IN
cord-287093-9mertwj7	180	20	replication	replication	NN
cord-287093-9mertwj7	180	21	complexes	complex	NNS
cord-287093-9mertwj7	180	22	among	among	IN
cord-287093-9mertwj7	180	23	three	three	CD
cord-287093-9mertwj7	180	24	genera	genus	NNS
cord-287093-9mertwj7	180	25	of	of	IN
cord-287093-9mertwj7	180	26	Picornaviridae	Picornaviridae	NNP
cord-287093-9mertwj7	180	27	Effects	effect	NNS
cord-287093-9mertwj7	180	28	of	of	IN
cord-287093-9mertwj7	180	29	foot	foot	NN
cord-287093-9mertwj7	180	30	-	-	HYPH
cord-287093-9mertwj7	180	31	and	and	CC
cord-287093-9mertwj7	180	32	-	-	HYPH
cord-287093-9mertwj7	180	33	mouth	mouth	NN
cord-287093-9mertwj7	180	34	disease	disease	NN
cord-287093-9mertwj7	180	35	virus	virus	NN
cord-287093-9mertwj7	180	36	nonstructural	nonstructural	JJ
cord-287093-9mertwj7	180	37	proteins	protein	NNS
cord-287093-9mertwj7	180	38	on	on	IN
cord-287093-9mertwj7	180	39	the	the	DT
cord-287093-9mertwj7	180	40	structure	structure	NN
cord-287093-9mertwj7	180	41	and	and	CC
cord-287093-9mertwj7	180	42	function	function	NN
cord-287093-9mertwj7	180	43	of	of	IN
cord-287093-9mertwj7	180	44	the	the	DT
cord-287093-9mertwj7	180	45	early	early	JJ
cord-287093-9mertwj7	180	46	secretory	secretory	JJ
cord-287093-9mertwj7	180	47	pathway	pathway	NN
cord-287093-9mertwj7	180	48	:	:	:
cord-287093-9mertwj7	180	49	2BC	2bc	NN
cord-287093-9mertwj7	180	50	but	but	CC
cord-287093-9mertwj7	180	51	not	not	RB
cord-287093-9mertwj7	180	52	3A	3A	NNP
cord-287093-9mertwj7	180	53	blocks	block	VBZ
cord-287093-9mertwj7	180	54	endoplasmic	endoplasmic	NN
cord-287093-9mertwj7	180	55	reticulum	reticulum	NN
cord-287093-9mertwj7	180	56	-	-	HYPH
cord-287093-9mertwj7	180	57	to	to	IN
cord-287093-9mertwj7	180	58	-	-	HYPH
cord-287093-9mertwj7	180	59	Golgi	golgi	NN
cord-287093-9mertwj7	180	60	transport	transport	NN
cord-287093-9mertwj7	180	61	Inhibition	inhibition	NN
cord-287093-9mertwj7	180	62	of	of	IN
cord-287093-9mertwj7	180	63	the	the	DT
cord-287093-9mertwj7	180	64	secretory	secretory	JJ
cord-287093-9mertwj7	180	65	pathway	pathway	NN
cord-287093-9mertwj7	180	66	by	by	IN
cord-287093-9mertwj7	180	67	footand	footand	NN
cord-287093-9mertwj7	180	68	-	-	HYPH
cord-287093-9mertwj7	180	69	mouth	mouth	NN
cord-287093-9mertwj7	180	70	disease	disease	NN
cord-287093-9mertwj7	180	71	virus	virus	NN
cord-287093-9mertwj7	181	1	2BC	2bc	NN
cord-287093-9mertwj7	181	2	protein	protein	NN
cord-287093-9mertwj7	181	3	is	be	VBZ
cord-287093-9mertwj7	181	4	reproduced	reproduce	VBN
cord-287093-9mertwj7	181	5	by	by	IN
cord-287093-9mertwj7	181	6	coexpression	coexpression	NN
cord-287093-9mertwj7	181	7	of	of	IN
cord-287093-9mertwj7	181	8	2B	2B	NNP
cord-287093-9mertwj7	181	9	with	with	IN
cord-287093-9mertwj7	181	10	2C	2C	NNP
cord-287093-9mertwj7	181	11	,	,	,
cord-287093-9mertwj7	181	12	and	and	CC
cord-287093-9mertwj7	181	13	the	the	DT
cord-287093-9mertwj7	181	14	site	site	NN
cord-287093-9mertwj7	181	15	of	of	IN
cord-287093-9mertwj7	181	16	inhibition	inhibition	NN
cord-287093-9mertwj7	181	17	is	be	VBZ
cord-287093-9mertwj7	181	18	determined	determine	VBN
cord-287093-9mertwj7	181	19	by	by	IN
cord-287093-9mertwj7	181	20	the	the	DT
cord-287093-9mertwj7	181	21	subcellular	subcellular	JJ
cord-287093-9mertwj7	181	22	location	location	NN
cord-287093-9mertwj7	181	23	of	of	IN
cord-287093-9mertwj7	181	24	2C	2C	NNP
cord-287093-9mertwj7	181	25	Recruitment	Recruitment	NNP
cord-287093-9mertwj7	181	26	and	and	CC
cord-287093-9mertwj7	181	27	activation	activation	NN
cord-287093-9mertwj7	181	28	of	of	IN
cord-287093-9mertwj7	181	29	a	a	DT
cord-287093-9mertwj7	181	30	lipid	lipid	NN
cord-287093-9mertwj7	181	31	kinase	kinase	NN
cord-287093-9mertwj7	181	32	by	by	IN
cord-287093-9mertwj7	181	33	hepatitis	hepatitis	NN
cord-287093-9mertwj7	181	34	C	C	NNP
cord-287093-9mertwj7	181	35	virus	virus	NN
cord-287093-9mertwj7	181	36	NS5A	NS5A	NNP
cord-287093-9mertwj7	181	37	is	be	VBZ
cord-287093-9mertwj7	181	38	essential	essential	JJ
cord-287093-9mertwj7	181	39	for	for	IN
cord-287093-9mertwj7	181	40	integrity	integrity	NN
cord-287093-9mertwj7	181	41	of	of	IN
cord-287093-9mertwj7	181	42	the	the	DT
cord-287093-9mertwj7	181	43	membranous	membranous	JJ
cord-287093-9mertwj7	181	44	replication	replication	NN
cord-287093-9mertwj7	181	45	compartment	compartment	NN
cord-287093-9mertwj7	182	1	The	the	DT
cord-287093-9mertwj7	182	2	membrane	membrane	NN
cord-287093-9mertwj7	182	3	web	web	NN
cord-287093-9mertwj7	182	4	generated	generate	VBN
cord-287093-9mertwj7	182	5	from	from	IN
cord-287093-9mertwj7	182	6	the	the	DT
cord-287093-9mertwj7	182	7	endoplsmic	endoplsmic	JJ
cord-287093-9mertwj7	182	8	reticulum	reticulum	NN
cord-287093-9mertwj7	182	9	(	(	-LRB-
cord-287093-9mertwj7	182	10	ER	ER	NNP
cord-287093-9mertwj7	182	11	)	)	-RRB-
cord-287093-9mertwj7	182	12	during	during	IN
cord-287093-9mertwj7	182	13	hepatitis	hepatitis	NN
cord-287093-9mertwj7	182	14	C	C	NNP
cord-287093-9mertwj7	182	15	replication	replication	NN
cord-287093-9mertwj7	182	16	contains	contain	VBZ
cord-287093-9mertwj7	182	17	eleveated	eleveated	JJ
cord-287093-9mertwj7	182	18	levels	level	NNS
cord-287093-9mertwj7	182	19	of	of	IN
cord-287093-9mertwj7	182	20	phosphatidylinositol-4-phosphate	phosphatidylinositol-4-phosphate	NNP
cord-287093-9mertwj7	182	21	.	.	.
cord-287093-9mertwj7	183	1	The	the	DT
cord-287093-9mertwj7	183	2	NS5A	NS5A	NNP
cord-287093-9mertwj7	183	3	protein	protein	NN
cord-287093-9mertwj7	183	4	of	of	IN
cord-287093-9mertwj7	183	5	hepatitis	hepatitis	NN
cord-287093-9mertwj7	183	6	C	C	NNP
cord-287093-9mertwj7	183	7	locates	locate	VBZ
cord-287093-9mertwj7	183	8	to	to	IN
cord-287093-9mertwj7	183	9	ER	ER	NNP
cord-287093-9mertwj7	183	10	and	and	CC
cord-287093-9mertwj7	183	11	binds	bind	VBZ
cord-287093-9mertwj7	183	12	phosphatidylinositol-4-kinase	phosphatidylinositol-4-kinase	NNP
cord-287093-9mertwj7	183	13	-	-	HYPH
cord-287093-9mertwj7	183	14	III	III	NNP
cord-287093-9mertwj7	183	15	and	and	CC
cord-287093-9mertwj7	183	16	stimulates	stimulate	VBZ
cord-287093-9mertwj7	183	17	kinase	kinase	NN
cord-287093-9mertwj7	183	18	activity	activity	NN
cord-287093-9mertwj7	183	19	.	.	.
cord-287093-9mertwj7	184	1	Knockdown	knockdown	NN
cord-287093-9mertwj7	184	2	of	of	IN
cord-287093-9mertwj7	184	3	phosphatidylinositol-4-kinase	phosphatidylinositol-4-kinase	NNP
cord-287093-9mertwj7	184	4	-	-	HYPH
cord-287093-9mertwj7	184	5	III	III	NNP
cord-287093-9mertwj7	184	6	reduces	reduce	VBZ
cord-287093-9mertwj7	184	7	replication	replication	NN
cord-287093-9mertwj7	184	8	.	.	.
cord-287093-9mertwj7	185	1	Hepatitus	Hepatitus	NNP
cord-287093-9mertwj7	185	2	C	C	NNP
cord-287093-9mertwj7	185	3	replication	replication	NN
cord-287093-9mertwj7	185	4	is	be	VBZ
cord-287093-9mertwj7	185	5	therefore	therefore	RB
cord-287093-9mertwj7	185	6	facilitated	facilitate	VBN
cord-287093-9mertwj7	185	7	by	by	IN
cord-287093-9mertwj7	185	8	production	production	NN
cord-287093-9mertwj7	185	9	of	of	IN
cord-287093-9mertwj7	185	10	phosphatidylinositol-4-phosphate	phosphatidylinositol-4-phosphate	NNP
cord-287093-9mertwj7	185	11	on	on	IN
cord-287093-9mertwj7	185	12	the	the	DT
cord-287093-9mertwj7	185	13	cytoplsmic	cytoplsmic	JJ
cord-287093-9mertwj7	185	14	face	face	NN
cord-287093-9mertwj7	185	15	of	of	IN
cord-287093-9mertwj7	185	16	the	the	DT
cord-287093-9mertwj7	185	17	ER	ER	NNP
cord-287093-9mertwj7	185	18	and	and	CC
cord-287093-9mertwj7	185	19	this	this	DT
cord-287093-9mertwj7	185	20	may	may	MD
cord-287093-9mertwj7	185	21	facilitate	facilitate	VB
cord-287093-9mertwj7	185	22	recruitment	recruitment	NN
cord-287093-9mertwj7	185	23	of	of	IN
cord-287093-9mertwj7	185	24	the	the	DT
cord-287093-9mertwj7	185	25	RNA	RNA	NNP
cord-287093-9mertwj7	185	26	polymerase	polymerase	NN
cord-287093-9mertwj7	185	27	Roles	role	NNS
cord-287093-9mertwj7	185	28	for	for	IN
cord-287093-9mertwj7	185	29	endocytic	endocytic	JJ
cord-287093-9mertwj7	185	30	trafficking	trafficking	NN
cord-287093-9mertwj7	185	31	and	and	CC
cord-287093-9mertwj7	185	32	phosphatidylinositol	phosphatidylinositol	JJ
cord-287093-9mertwj7	185	33	4-kinase	4-kinase	CD
cord-287093-9mertwj7	185	34	III	iii	CD
cord-287093-9mertwj7	185	35	alpha	alpha	NN
cord-287093-9mertwj7	185	36	in	in	IN
cord-287093-9mertwj7	185	37	hepatitis	hepatitis	NNP
cord-287093-9mertwj7	185	38	C	C	NNP
cord-287093-9mertwj7	185	39	virus	virus	NN
cord-287093-9mertwj7	185	40	replication	replication	NN
cord-287093-9mertwj7	186	1	The	the	DT
cord-287093-9mertwj7	186	2	study	study	NN
cord-287093-9mertwj7	186	3	shows	show	VBZ
cord-287093-9mertwj7	186	4	that	that	IN
cord-287093-9mertwj7	186	5	the	the	DT
cord-287093-9mertwj7	186	6	lipid	lipid	NN
cord-287093-9mertwj7	186	7	kinase	kinase	NN
cord-287093-9mertwj7	186	8	phosphatidylinositol-4-kinase	phosphatidylinositol-4-kinase	NNP
cord-287093-9mertwj7	186	9	III	iii	CD
cord-287093-9mertwj7	186	10	alpha	alpha	NN
cord-287093-9mertwj7	186	11	is	be	VBZ
cord-287093-9mertwj7	186	12	important	important	JJ
cord-287093-9mertwj7	186	13	for	for	IN
cord-287093-9mertwj7	186	14	hepatitis	hepatitis	NN
cord-287093-9mertwj7	186	15	C	C	NNP
cord-287093-9mertwj7	186	16	replication	replication	NN
cord-287093-9mertwj7	186	17	Human	Human	NNP
cord-287093-9mertwj7	186	18	VAP	VAP	NNP
cord-287093-9mertwj7	186	19	-	-	HYPH
cord-287093-9mertwj7	186	20	B	B	NNP
cord-287093-9mertwj7	186	21	is	be	VBZ
cord-287093-9mertwj7	186	22	involved	involve	VBN
cord-287093-9mertwj7	186	23	in	in	IN
cord-287093-9mertwj7	186	24	hepatitis	hepatitis	NN
cord-287093-9mertwj7	186	25	C	C	NNP
cord-287093-9mertwj7	186	26	virus	virus	NN
cord-287093-9mertwj7	186	27	replication	replication	NN
cord-287093-9mertwj7	186	28	through	through	IN
cord-287093-9mertwj7	186	29	interaction	interaction	NN
cord-287093-9mertwj7	186	30	with	with	IN
cord-287093-9mertwj7	186	31	NS5A	NS5A	NNP
cord-287093-9mertwj7	187	1	and	and	CC
cord-287093-9mertwj7	187	2	NS5B	NS5B	NNP
cord-287093-9mertwj7	187	3	Participation	Participation	NNP
cord-287093-9mertwj7	187	4	of	of	IN
cord-287093-9mertwj7	187	5	rab5	rab5	NNP
cord-287093-9mertwj7	187	6	,	,	,
cord-287093-9mertwj7	187	7	an	an	DT
cord-287093-9mertwj7	187	8	early	early	JJ
cord-287093-9mertwj7	187	9	endosome	endosome	NN
cord-287093-9mertwj7	187	10	protein	protein	NN
cord-287093-9mertwj7	187	11	,	,	,
cord-287093-9mertwj7	187	12	in	in	IN
cord-287093-9mertwj7	187	13	hepatitis	hepatitis	NNP
cord-287093-9mertwj7	187	14	C	C	NNP
cord-287093-9mertwj7	187	15	virus	virus	NN
cord-287093-9mertwj7	187	16	RNA	RNA	NNP
cord-287093-9mertwj7	187	17	replication	replication	NN
cord-287093-9mertwj7	187	18	machinery	machinery	NN
cord-287093-9mertwj7	187	19	Coronavirus	Coronavirus	NNP
cord-287093-9mertwj7	187	20	replication	replication	NN
cord-287093-9mertwj7	187	21	complex	complex	JJ
cord-287093-9mertwj7	187	22	formation	formation	NN
cord-287093-9mertwj7	187	23	utilizes	utilize	VBZ
cord-287093-9mertwj7	187	24	components	component	NNS
cord-287093-9mertwj7	187	25	of	of	IN
cord-287093-9mertwj7	187	26	cellular	cellular	JJ
cord-287093-9mertwj7	187	27	autophagy	autophagy	NN
cord-287093-9mertwj7	187	28	Virgin	Virgin	NNP
cord-287093-9mertwj7	187	29	HW	HW	NNP
cord-287093-9mertwj7	187	30	:	:	:
cord-287093-9mertwj7	187	31	Coronavirus	Coronavirus	NNP
cord-287093-9mertwj7	187	32	replication	replication	NN
cord-287093-9mertwj7	187	33	does	do	VBZ
cord-287093-9mertwj7	187	34	not	not	RB
cord-287093-9mertwj7	187	35	require	require	VB
cord-287093-9mertwj7	187	36	the	the	DT
cord-287093-9mertwj7	187	37	autophagy	autophagy	NN
cord-287093-9mertwj7	187	38	gene	gene	NN
cord-287093-9mertwj7	187	39	ATG5	ATG5	NNP
cord-287093-9mertwj7	187	40	Coronavirus	Coronavirus	NNP
cord-287093-9mertwj7	187	41	nsp6	nsp6	NN
cord-287093-9mertwj7	187	42	proteins	protein	NNS
cord-287093-9mertwj7	187	43	generate	generate	VBP
cord-287093-9mertwj7	187	44	autophagosomes	autophagosome	NNS
cord-287093-9mertwj7	187	45	from	from	IN
cord-287093-9mertwj7	187	46	the	the	DT
cord-287093-9mertwj7	187	47	endoplasmic	endoplasmic	NN
cord-287093-9mertwj7	187	48	reticulum	reticulum	NN
cord-287093-9mertwj7	187	49	via	via	IN
cord-287093-9mertwj7	187	50	an	an	DT
cord-287093-9mertwj7	187	51	omegasome	omegasome	NN
cord-287093-9mertwj7	187	52	intermediate	intermediate	JJ
cord-287093-9mertwj7	187	53	Identification	Identification	NNP
cord-287093-9mertwj7	187	54	of	of	IN
cord-287093-9mertwj7	187	55	cornavirus	cornavirus	NNP
cord-287093-9mertwj7	187	56	proteins	protein	NNS
cord-287093-9mertwj7	187	57	able	able	JJ
cord-287093-9mertwj7	187	58	to	to	TO
cord-287093-9mertwj7	187	59	stimulate	stimulate	VB
cord-287093-9mertwj7	187	60	starvation	starvation	NN
cord-287093-9mertwj7	187	61	independent	independent	JJ
cord-287093-9mertwj7	187	62	formation	formation	NN
cord-287093-9mertwj7	187	63	of	of	IN
cord-287093-9mertwj7	187	64	autophagosomes	autophagosomes	NNP
cord-287093-9mertwj7	187	65	directly	directly	RB
cord-287093-9mertwj7	187	66	from	from	IN
cord-287093-9mertwj7	187	67	the	the	DT
cord-287093-9mertwj7	187	68	endoplasmic	endoplasmic	NN
cord-287093-9mertwj7	187	69	reticulum	reticulum	NN
cord-287093-9mertwj7	187	70	via	via	IN
cord-287093-9mertwj7	187	71	an	an	DT
cord-287093-9mertwj7	187	72	omegosome	omegosome	VBN
cord-287093-9mertwj7	187	73	intermediate	intermediate	JJ
cord-287093-9mertwj7	187	74	Autophagosome	Autophagosome	NNP
cord-287093-9mertwj7	187	75	formation	formation	NN
cord-287093-9mertwj7	187	76	from	from	IN
cord-287093-9mertwj7	187	77	membrane	membrane	NN
cord-287093-9mertwj7	187	78	compartments	compartment	NNS
cord-287093-9mertwj7	187	79	enriched	enrich	VBN
cord-287093-9mertwj7	187	80	in	in	IN
cord-287093-9mertwj7	187	81	phosphatidylinositol	phosphatidylinositol	JJ
cord-287093-9mertwj7	187	82	3-phosphate	3-phosphate	CD
cord-287093-9mertwj7	187	83	and	and	CC
cord-287093-9mertwj7	187	84	dynamically	dynamically	RB
cord-287093-9mertwj7	187	85	connected	connect	VBN
cord-287093-9mertwj7	187	86	to	to	IN
cord-287093-9mertwj7	187	87	the	the	DT
cord-287093-9mertwj7	187	88	endoplasmic	endoplasmic	NN
cord-287093-9mertwj7	187	89	reticulum	reticulum	NN
cord-287093-9mertwj7	187	90	Coronaviruses	Coronaviruses	NNP
cord-287093-9mertwj7	187	91	hijack	hijack	VBP
cord-287093-9mertwj7	187	92	the	the	DT
cord-287093-9mertwj7	187	93	LC3-I	LC3-I	NNP
cord-287093-9mertwj7	187	94	-	-	HYPH
cord-287093-9mertwj7	187	95	positive	positive	JJ
cord-287093-9mertwj7	187	96	EDEMosomes	edemosome	NNS
cord-287093-9mertwj7	187	97	,	,	,
cord-287093-9mertwj7	187	98	ER	ER	NNP
cord-287093-9mertwj7	187	99	-	-	HYPH
cord-287093-9mertwj7	187	100	derived	derive	VBN
cord-287093-9mertwj7	187	101	vesicles	vesicle	NNS
cord-287093-9mertwj7	187	102	exporting	export	VBG
cord-287093-9mertwj7	187	103	short	short	RB
cord-287093-9mertwj7	187	104	-	-	HYPH
cord-287093-9mertwj7	187	105	lived	live	VBN
cord-287093-9mertwj7	187	106	ERAD	ERAD	NNP
cord-287093-9mertwj7	187	107	regulators	regulator	NNS
cord-287093-9mertwj7	187	108	,	,	,
cord-287093-9mertwj7	187	109	for	for	IN
cord-287093-9mertwj7	187	110	replication	replication	NN
cord-287093-9mertwj7	187	111	EDEMosomes	edemosome	NNS
cord-287093-9mertwj7	187	112	are	be	VBP
cord-287093-9mertwj7	187	113	ER	er	NN
cord-287093-9mertwj7	187	114	-	-	HYPH
cord-287093-9mertwj7	187	115	derived	derive	VBN
cord-287093-9mertwj7	187	116	vesicles	vesicle	NNS
cord-287093-9mertwj7	187	117	that	that	WDT
cord-287093-9mertwj7	187	118	transport	transport	NN
cord-287093-9mertwj7	187	119	ER	er	NN
cord-287093-9mertwj7	187	120	chaperones	chaperone	NNS
cord-287093-9mertwj7	187	121	to	to	IN
cord-287093-9mertwj7	187	122	endosomes	endosome	NNS
cord-287093-9mertwj7	187	123	.	.	.
cord-287093-9mertwj7	188	1	Double	double	JJ
cord-287093-9mertwj7	188	2	-	-	HYPH
cord-287093-9mertwj7	188	3	membraned	membraned	JJ
cord-287093-9mertwj7	188	4	vesicles	vesicle	NNS
cord-287093-9mertwj7	188	5	induced	induce	VBN
cord-287093-9mertwj7	188	6	by	by	IN
cord-287093-9mertwj7	188	7	the	the	DT
cord-287093-9mertwj7	188	8	murine	murine	JJ
cord-287093-9mertwj7	188	9	cornaviruses	cornaviruse	NNS
cord-287093-9mertwj7	188	10	,	,	,
cord-287093-9mertwj7	188	11	mouse	mouse	NNP
cord-287093-9mertwj7	188	12	hepatitis	hepatitis	NN
cord-287093-9mertwj7	188	13	virus	virus	NN
cord-287093-9mertwj7	188	14	(	(	-LRB-
cord-287093-9mertwj7	188	15	MHV	MHV	NNP
cord-287093-9mertwj7	188	16	)	)	-RRB-
cord-287093-9mertwj7	188	17	,	,	,
cord-287093-9mertwj7	188	18	recruit	recruit	VB
cord-287093-9mertwj7	188	19	EDEMosome	edemosome	NN
cord-287093-9mertwj7	188	20	marker	marker	NN
cord-287093-9mertwj7	188	21	EDEM1	EDEM1	NNS
cord-287093-9mertwj7	188	22	and	and	CC
cord-287093-9mertwj7	188	23	a	a	DT
cord-287093-9mertwj7	188	24	non	non	JJ
cord-287093-9mertwj7	188	25	-	-	JJ
cord-287093-9mertwj7	188	26	lipidated	lipidated	JJ
cord-287093-9mertwj7	188	27	LC3	lc3	NN
cord-287093-9mertwj7	188	28	by	by	IN
cord-287093-9mertwj7	188	29	a	a	DT
cord-287093-9mertwj7	188	30	pathaway	pathaway	NN
cord-287093-9mertwj7	188	31	independent	independent	JJ
cord-287093-9mertwj7	188	32	of	of	IN
cord-287093-9mertwj7	188	33	autophagy	autophagy	NN
cord-287093-9mertwj7	188	34	Modification	modification	NN
cord-287093-9mertwj7	188	35	of	of	IN
cord-287093-9mertwj7	188	36	cellular	cellular	JJ
cord-287093-9mertwj7	188	37	autophagy	autophagy	NN
cord-287093-9mertwj7	188	38	protein	protein	NN
cord-287093-9mertwj7	188	39	LC3	lc3	NN
cord-287093-9mertwj7	188	40	by	by	IN
cord-287093-9mertwj7	188	41	poliovirus	poliovirus	NN
cord-287093-9mertwj7	189	1	A	a	DT
cord-287093-9mertwj7	189	2	guide	guide	NN
cord-287093-9mertwj7	189	3	to	to	IN
cord-287093-9mertwj7	189	4	viral	viral	JJ
cord-287093-9mertwj7	189	5	inclusions	inclusion	NNS
cord-287093-9mertwj7	189	6	,	,	,
cord-287093-9mertwj7	189	7	membrane	membrane	NN
cord-287093-9mertwj7	189	8	rearrangements	rearrangement	NNS
cord-287093-9mertwj7	189	9	,	,	,
cord-287093-9mertwj7	189	10	factories	factory	NNS
cord-287093-9mertwj7	189	11	,	,	,
cord-287093-9mertwj7	189	12	and	and	CC
cord-287093-9mertwj7	189	13	viroplasm	viroplasm	NN
cord-287093-9mertwj7	189	14	produced	produce	VBN
cord-287093-9mertwj7	189	15	during	during	IN
cord-287093-9mertwj7	189	16	virus	virus	NN
cord-287093-9mertwj7	189	17	replication	replication	NN
cord-287093-9mertwj7	190	1	Aggresomes	Aggresomes	NNP
cord-287093-9mertwj7	190	2	resemble	resemble	VBP
cord-287093-9mertwj7	190	3	sites	site	NNS
cord-287093-9mertwj7	190	4	specialized	specialize	VBN
cord-287093-9mertwj7	190	5	for	for	IN
cord-287093-9mertwj7	190	6	virus	virus	NN
cord-287093-9mertwj7	190	7	assembly	assembly	NNP
cord-287093-9mertwj7	190	8	Aggresomes	Aggresomes	NNP
cord-287093-9mertwj7	190	9	and	and	CC
cord-287093-9mertwj7	190	10	pericentriolar	pericentriolar	NNP
cord-287093-9mertwj7	190	11	sites	site	NNS
cord-287093-9mertwj7	190	12	of	of	IN
cord-287093-9mertwj7	190	13	virus	virus	NN
cord-287093-9mertwj7	190	14	assembly	assembly	NN
cord-287093-9mertwj7	190	15	:	:	:
cord-287093-9mertwj7	190	16	cellular	cellular	JJ
cord-287093-9mertwj7	190	17	defense	defense	NN
cord-287093-9mertwj7	190	18	or	or	CC
cord-287093-9mertwj7	190	19	viral	viral	JJ
cord-287093-9mertwj7	190	20	design	design	NN
cord-287093-9mertwj7	190	21	?	?	.
cord-287093-9mertwj7	191	1	Aggresomes	Aggresomes	NNP
cord-287093-9mertwj7	191	2	and	and	CC
cord-287093-9mertwj7	191	3	autophagy	autophagy	NN
cord-287093-9mertwj7	191	4	generate	generate	VBP
cord-287093-9mertwj7	191	5	sites	site	NNS
cord-287093-9mertwj7	191	6	for	for	IN
cord-287093-9mertwj7	191	7	viral	viral	JJ
cord-287093-9mertwj7	191	8	infection	infection	NN
cord-287093-9mertwj7	192	1	Vimentin	vimentin	NN
cord-287093-9mertwj7	192	2	rearrangement	rearrangement	NN
cord-287093-9mertwj7	192	3	during	during	IN
cord-287093-9mertwj7	192	4	African	african	JJ
cord-287093-9mertwj7	192	5	swine	swine	NN
cord-287093-9mertwj7	192	6	fever	fever	NN
cord-287093-9mertwj7	192	7	virus	virus	NN
cord-287093-9mertwj7	192	8	infection	infection	NN
cord-287093-9mertwj7	192	9	involves	involve	VBZ
cord-287093-9mertwj7	192	10	retrograde	retrograde	JJ
cord-287093-9mertwj7	192	11	transport	transport	NN
cord-287093-9mertwj7	192	12	along	along	IN
cord-287093-9mertwj7	192	13	microtubules	microtubule	NNS
cord-287093-9mertwj7	192	14	and	and	CC
cord-287093-9mertwj7	192	15	phosphorylation	phosphorylation	NN
cord-287093-9mertwj7	192	16	of	of	IN
cord-287093-9mertwj7	192	17	vimentin	vimentin	NNS
cord-287093-9mertwj7	192	18	by	by	IN
cord-287093-9mertwj7	192	19	calcium	calcium	NN
cord-287093-9mertwj7	192	20	calmodulin	calmodulin	NN
cord-287093-9mertwj7	192	21	kinase	kinase	VBZ
cord-287093-9mertwj7	192	22	II	II	NNP
cord-287093-9mertwj7	192	23	Interaction	Interaction	NNP
cord-287093-9mertwj7	192	24	of	of	IN
cord-287093-9mertwj7	192	25	frog	frog	NN
cord-287093-9mertwj7	192	26	virus	virus	NN
cord-287093-9mertwj7	192	27	3	3	CD
cord-287093-9mertwj7	192	28	with	with	IN
cord-287093-9mertwj7	192	29	the	the	DT
cord-287093-9mertwj7	192	30	cytomatrix	cytomatrix	NNP
cord-287093-9mertwj7	192	31	.	.	.
cord-287093-9mertwj7	193	1	IV	IV	NNP
cord-287093-9mertwj7	193	2	.	.	.
cord-287093-9mertwj7	194	1	Phosphorylation	Phosphorylation	NNP
cord-287093-9mertwj7	194	2	of	of	IN
cord-287093-9mertwj7	194	3	vimentin	vimentin	NN
cord-287093-9mertwj7	194	4	precedes	precede	VBZ
cord-287093-9mertwj7	194	5	the	the	DT
cord-287093-9mertwj7	194	6	reorganization	reorganization	NN
cord-287093-9mertwj7	194	7	of	of	IN
cord-287093-9mertwj7	194	8	intermediate	intermediate	JJ
cord-287093-9mertwj7	194	9	filaments	filament	NNS
cord-287093-9mertwj7	194	10	around	around	IN
cord-287093-9mertwj7	194	11	the	the	DT
cord-287093-9mertwj7	194	12	virus	virus	NN
cord-287093-9mertwj7	194	13	assembly	assembly	NN
cord-287093-9mertwj7	194	14	sites	site	NNS
cord-287093-9mertwj7	194	15	Colocalization	Colocalization	NNP
cord-287093-9mertwj7	194	16	of	of	IN
cord-287093-9mertwj7	194	17	transcription	transcription	NN
cord-287093-9mertwj7	194	18	and	and	CC
cord-287093-9mertwj7	194	19	translation	translation	NN
cord-287093-9mertwj7	194	20	within	within	IN
cord-287093-9mertwj7	194	21	cytoplasmic	cytoplasmic	JJ
cord-287093-9mertwj7	194	22	poxvirus	poxvirus	NNP
cord-287093-9mertwj7	194	23	factories	factory	NNS
cord-287093-9mertwj7	194	24	coordinates	coordinate	VBZ
cord-287093-9mertwj7	194	25	viral	viral	JJ
cord-287093-9mertwj7	194	26	expression	expression	NN
cord-287093-9mertwj7	194	27	and	and	CC
cord-287093-9mertwj7	194	28	subjugates	subjugate	VBZ
cord-287093-9mertwj7	194	29	host	host	NN
cord-287093-9mertwj7	194	30	functions	function	NNS
cord-287093-9mertwj7	194	31	Demonstrated	demonstrate	VBD
cord-287093-9mertwj7	194	32	that	that	IN
cord-287093-9mertwj7	194	33	individual	individual	JJ
cord-287093-9mertwj7	194	34	NCLDV	NCLDV	NNP
cord-287093-9mertwj7	194	35	factories	factory	NNS
cord-287093-9mertwj7	194	36	are	be	VBP
cord-287093-9mertwj7	194	37	compartmentalised	compartmentalise	VBN
cord-287093-9mertwj7	194	38	and	and	CC
cord-287093-9mertwj7	194	39	represent	represent	VB
cord-287093-9mertwj7	194	40	separate	separate	JJ
cord-287093-9mertwj7	194	41	functional	functional	JJ
cord-287093-9mertwj7	194	42	units	unit	NNS
cord-287093-9mertwj7	194	43	within	within	IN
cord-287093-9mertwj7	194	44	the	the	DT
cord-287093-9mertwj7	194	45	cell	cell	NN
cord-287093-9mertwj7	194	46	Regulation	regulation	NN
cord-287093-9mertwj7	194	47	of	of	IN
cord-287093-9mertwj7	194	48	host	host	NN
cord-287093-9mertwj7	194	49	translational	translational	JJ
cord-287093-9mertwj7	194	50	machinery	machinery	NN
cord-287093-9mertwj7	194	51	by	by	IN
cord-287093-9mertwj7	194	52	African	african	JJ
cord-287093-9mertwj7	194	53	swine	swine	NN
cord-287093-9mertwj7	194	54	fever	fever	NN
cord-287093-9mertwj7	194	55	virus	virus	NN
cord-287093-9mertwj7	194	56	Formation	formation	NN
cord-287093-9mertwj7	194	57	of	of	IN
cord-287093-9mertwj7	194	58	antiviral	antiviral	JJ
cord-287093-9mertwj7	194	59	cytoplasmic	cytoplasmic	JJ
cord-287093-9mertwj7	194	60	granules	granule	NNS
cord-287093-9mertwj7	194	61	during	during	IN
cord-287093-9mertwj7	194	62	orthopoxvirus	orthopoxvirus	NNP
cord-287093-9mertwj7	194	63	infection	infection	NN
cord-287093-9mertwj7	194	64	Inhibition	Inhibition	NNP
cord-287093-9mertwj7	194	65	of	of	IN
cord-287093-9mertwj7	194	66	a	a	DT
cord-287093-9mertwj7	194	67	large	large	JJ
cord-287093-9mertwj7	194	68	double	double	RB
cord-287093-9mertwj7	194	69	-	-	HYPH
cord-287093-9mertwj7	194	70	stranded	stranded	JJ
cord-287093-9mertwj7	194	71	DNA	dna	NN
cord-287093-9mertwj7	194	72	virus	virus	NN
cord-287093-9mertwj7	194	73	by	by	IN
cord-287093-9mertwj7	194	74	MxA	MxA	NNP
cord-287093-9mertwj7	194	75	protein	protein	NN
cord-287093-9mertwj7	195	1	Engineered	engineer	VBN
cord-287093-9mertwj7	195	2	retargeting	retargeting	NN
cord-287093-9mertwj7	195	3	of	of	IN
cord-287093-9mertwj7	195	4	viral	viral	JJ
cord-287093-9mertwj7	195	5	RNA	RNA	NNP
cord-287093-9mertwj7	195	6	replication	replication	NN
cord-287093-9mertwj7	195	7	complexes	complex	NNS
cord-287093-9mertwj7	195	8	to	to	IN
cord-287093-9mertwj7	195	9	an	an	DT
cord-287093-9mertwj7	195	10	alternative	alternative	JJ
cord-287093-9mertwj7	195	11	intracellular	intracellular	JJ
cord-287093-9mertwj7	195	12	membrane	membrane	NN
cord-287093-9mertwj7	196	1	The	the	DT
cord-287093-9mertwj7	196	2	authors	author	NNS
cord-287093-9mertwj7	196	3	would	would	MD
cord-287093-9mertwj7	196	4	like	like	VB
cord-287093-9mertwj7	196	5	to	to	TO
cord-287093-9mertwj7	196	6	thank	thank	VB
cord-287093-9mertwj7	196	7	Jeanmarie	Jeanmarie	NNP
cord-287093-9mertwj7	196	8	Verchot	Verchot	NNP
cord-287093-9mertwj7	196	9	for	for	IN
cord-287093-9mertwj7	196	10	helpful	helpful	JJ
cord-287093-9mertwj7	196	11	discussions	discussion	NNS
cord-287093-9mertwj7	196	12	during	during	IN
cord-287093-9mertwj7	196	13	the	the	DT
cord-287093-9mertwj7	196	14	preparation	preparation	NN
cord-287093-9mertwj7	196	15	of	of	IN
cord-287093-9mertwj7	196	16	this	this	DT
cord-287093-9mertwj7	196	17	manuscript	manuscript	NN
cord-287093-9mertwj7	196	18	.	.	.
cord-287093-9mertwj7	197	1	TW	TW	NNP
cord-287093-9mertwj7	197	2	is	be	VBZ
cord-287093-9mertwj7	197	3	supported	support	VBN
cord-287093-9mertwj7	197	4	by	by	IN
cord-287093-9mertwj7	197	5	BB	BB	NNP
cord-287093-9mertwj7	197	6	/	/	SYM
cord-287093-9mertwj7	197	7	E018521	E018521	NNP
cord-287093-9mertwj7	197	8	and	and	CC
cord-287093-9mertwj7	197	9	BB	BB	NNP
cord-287093-9mertwj7	197	10	/	/	SYM
cord-287093-9mertwj7	197	11	F012861	F012861	NNP
cord-287093-9mertwj7	197	12	grants	grant	NNS
cord-287093-9mertwj7	197	13	from	from	IN
cord-287093-9mertwj7	197	14	BBSRC	BBSRC	NNP
cord-287093-9mertwj7	197	15	.	.	.
cord-287093-9mertwj7	198	1	CN	CN	NNP
cord-287093-9mertwj7	198	2	is	be	VBZ
cord-287093-9mertwj7	198	3	supported	support	VBN
cord-287093-9mertwj7	198	4	by	by	IN
cord-287093-9mertwj7	198	5	BBSRC	BBSRC	NNP
cord-287093-9mertwj7	198	6	and	and	CC
cord-287093-9mertwj7	198	7	DEFRA	DEFRA	NNP
cord-287093-9mertwj7	198	8	(	(	-LRB-
cord-287093-9mertwj7	198	9	SE1541	SE1541	NNP
cord-287093-9mertwj7	198	10	)	)	-RRB-
cord-287093-9mertwj7	198	11	.	.	.
cord-287093-9mertwj7	199	1	Papers	paper	NNS
cord-287093-9mertwj7	199	2	of	of	IN
cord-287093-9mertwj7	199	3	particular	particular	JJ
cord-287093-9mertwj7	199	4	interest	interest	NN
cord-287093-9mertwj7	199	5	,	,	,
cord-287093-9mertwj7	199	6	published	publish	VBN
cord-287093-9mertwj7	199	7	within	within	IN
cord-287093-9mertwj7	199	8	the	the	DT
cord-287093-9mertwj7	199	9	period	period	NN
cord-287093-9mertwj7	199	10	of	of	IN
cord-287093-9mertwj7	199	11	review	review	NN
cord-287093-9mertwj7	199	12	,	,	,
cord-287093-9mertwj7	199	13	have	have	VBP
cord-287093-9mertwj7	199	14	been	be	VBN
cord-287093-9mertwj7	199	15	highlighted	highlight	VBN
cord-287093-9mertwj7	199	16	as	as	IN
cord-287093-9mertwj7	199	17	:	:	:
cord-287093-9mertwj7	199	18	of	of	IN
cord-287093-9mertwj7	199	19	special	special	JJ
cord-287093-9mertwj7	199	20	interest	interest	NN
cord-287093-9mertwj7	199	21	of	of	IN
cord-287093-9mertwj7	199	22	outstanding	outstanding	JJ
cord-287093-9mertwj7	199	23	interest	interest	NN