id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-017438-x12d2ewc	Gupta, Anita	MBL Deficiency as Risk of Infection and Autoimmunity	2012-03-20		.txt	text/plain	15406	783	44	The distribution of MBL gene polymorphisms was significantly different between patients with SARS and normal subjects, with a higher frequency of haplotypes associated with low or deficient serum levels of MBL in patients with SARS. Whether variant alleles of the MBL gene causing low serum concentrations of MBL are associated with increased susceptibility to RA and erosive outcome in an inception cohort of patients with early polyarthritis was studied by Jacobsen et al. SLE patients were associated with a reduced functional activity of the MBL pathway of complement, in relation to expression of MBL variant alleles, increased levels of autoantibodies against cardiolipin and C1q, but not against MBL. Polymorphisms of both codon 54 allele and promoter variants of the mannose MBL gene in patients with primary Sjogren's syndrome (SS) was suggested as one of the genetic factors that determines susceptibility to SS (Wang et al. Association of mannose-binding lectin gene variation with disease severity and infections in a population-based cohort of systemic lupus erythematosus patients	./cache/cord-017438-x12d2ewc.txt	./txt/cord-017438-x12d2ewc.txt