id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-011781-0yswqubf	Svanberg, Emilie Krite	Changes in pulmonary oxygen content are detectable with laser absorption spectroscopy: proof of concept in newborn piglets	2020-06-13		.txt	text/plain	4606	252	50	BACKGROUND: Using an optical method based on tunable diode laser absorption spectroscopy, we previously assessed oxygen (O(2)) and water vapor (H(2)O) content in a tissue phantom of the preterm infant lung. METHODS: Five mechanically ventilated piglets were subjected to stepwise increased and decreased fraction of inspired oxygen (FiO(2)), to atelectasis using a balloon catheter in the right bronchus, and to pneumothorax by injecting air in the pleural cavity. CONCLUSIONS: The optical method detected FiO(2) variations and discriminated the two induced lung pathologies, providing a rationale for further development into a minimally invasive device for real-time monitoring gas changes in the lungs of sick newborn infants. 14 We hypothesized that the GASMAS method with an external as well as an internal light source probe would detect changes in pulmonary O 2 gas concentration, including responses to induced local lung pathologies in newborn piglets.	./cache/cord-011781-0yswqubf.txt	./txt/cord-011781-0yswqubf.txt