id author title date pages extension mime words sentences flesch summary cache txt cord-009983-naht0ik6 Kim, Yoon Hee Transforming growth factor‐beta 1 in humidifier disinfectant‐associated children's interstitial lung disease 2015-06-25 .txt text/plain 4452 251 46 21 There have been many efforts to determine the clinical prognostic factors of the humidifier disinfectant-associated children's interstitial lung disease (HD-chILD) because this ILD progressed rapidly and was refractory to all treatment in non-survivors, whereas the clinical course in survivors tended to be highly favorable. These findings suggest that TGF-b1 may play a key role in the repair of damaged lung and control of excessive inflammation in acute lung injury, rather functioning in promoting the progression of irreversible, fatal fibrosis. 29, 30 In the HD-chILD of this study, the role of TGF-b1 seemed to be very complex in relating with repairing damaged lung, controlling severe inflammation, and promoting pulmonary fibrosis. In conclusion, this study confirmed the possible role of TGF-b1 in the repair of damaged lung and control of vigorous inflammation, in acute lung injury associated with unexpected exposure to humidifier disinfectants in young children. ./cache/cord-009983-naht0ik6.txt ./txt/cord-009983-naht0ik6.txt