id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-009766-mdmqcvww	Comerford, Andrew	Structured Tree Impedance Outflow Boundary Conditions for 3D Lung Simulations	2010-08-01		.txt	text/plain	6330	365	48	In this paper, we develop structured tree outflow boundary conditions for modeling the airflow in patient specific human lungs. Furthermore, simulations of a hypothetical diseased lung (restricted flow in the superior left lobe) under mechanical ventilation show that the mean pressure at the outlets of the 3D domain is about 28% higher. This hypothetical model illustrates potential causes of volutrauma in the human lung and furthermore demonstrates how different clinical scenarios can be studied without the need to assume the unknown flow distribution into the downstream region. Due to the acceleration periods and high frequency oscillations, the mechanical ventilation is expected to lead to different flow and pressure dynamics due to the considerably higher slew rates. In Fig. 6 , the spatial pressure distribution is compared for the two different boundary conditions: traction free ͑up to seven generation model͒ and impedance ͑seven generation model plus up to 13 generations of the 1D tree depending on the outlet size͒.	./cache/cord-009766-mdmqcvww.txt	./txt/cord-009766-mdmqcvww.txt