id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-000307-iv18eiap	Capelozzi, Vera Luiza	Pathological and ultrastructural analysis of surgical lung biopsies in patients with swine‐origin influenza type A/H1N1 and acute respiratory failure	2010-12-17		.txt	text/plain	3986	243	44	BACKGROUND: Cases of H1N1 and other pulmonary infections evolve to acute respiratory failure and death when co‐infections or lung injury predominate over the immune response, thus requiring early diagnosis to improve treatment. 6 Swine-origin influenza A (H1N1) virus infection can cause severe acute respiratory failure (ARF), requiring admission to an intensive care unit (ICU) in 15-30% of previously healthy young to middle-aged people. 14 Thus, pathological findings obtained by an OLB, coupled to ultrastructural and immunologic analysis, may have an impact on decisions about changes in treatment strategies employed for these critically ill patients, and also provide a greater understanding of the pathophysiology of S-OIV infection. The objective of this study was to analyze pathologically and ultrastructurally S-OIV lung infection and the pulmonary immune response in a series of five cases with OLB. This case series documents for the first time the pathological and ultrastructural findings of lung tissue from five patients admitted to the ICU with ARF and S-OIV infection who were submitted to OLB.	./cache/cord-000307-iv18eiap.txt	./txt/cord-000307-iv18eiap.txt