id author title date pages extension mime words sentences flesch summary cache txt cord-280850-lku2g69k Zhang, Shidong Aqueous extract of Bai-Hu-Tang, a classical Chinese herb formula, prevents excessive immune response and liver injury induced by LPS in rabbits 2013-08-26 .txt text/plain 3849 200 52 title: Aqueous extract of Bai-Hu-Tang, a classical Chinese herb formula, prevents excessive immune response and liver injury induced by LPS in rabbits In this study, a febrigenic dosage of LPS (15 mg/kg i.v.) was injected into rabbits to form an animal febrile model, then the model animals were gavaged with BHT at the same time, and the formula's function of liver damage prevention and immunomodulation was researched in rabbits. Therefore, BHT did not affect the activated adaptive immunity, but prevented the cell immunity inhibition and excessive cytokines in innate immunity by LPS at the same time. The gene expressions of TLR4 studied herein were not affected by BHT (Fig. 5A ), but LBP expression was increased (Fig. 5B) , which bind and transport LPS to activate cells in the immunity system (Knapp et al., 2006) , and inhibiting inflammatory response at higher concentration (Hamann et al., 2005) . ./cache/cord-280850-lku2g69k.txt ./txt/cord-280850-lku2g69k.txt