id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-006279-ib5z3elq	Ryter, Stefan W.	Heme oxygenase/carbon monoxide signaling pathways: Regulation and functional significance	2002		.txt	text/plain	8188	464	41	Recent studies have discovered a potent anti-inflammatory effect of CO: the inhibition of pro-inflammatory cytokine production following inducing stimuli, dependent on the modulation of mitogen activated protein kinase (MAPK)signaling cascades [6, 11] . This review will (I) describe the regulation of HO-1 as an inducible source of endogenous CO, (II) describe evidence that HO-1 acts as a mediator of cellular and tissue protection against oxidative stress, and (III) emphasize recent studies that introduce novel anti-apoptotic and anti-inflammatory properties of HO-derived CO in oxidative lung injury models. MKK3 mitogen activated protein kinase pathway mediates carbon monoxide-induced protection against oxidant-induced lung injury Activation of heme oxygenase and heat shock protein 70 genes by stress in human hepatoma cells Mitogen activated protein kinase (MAPK) pathway regulates heme oxygenase-1 gene expression by hypoxia in vascular cells	./cache/cord-006279-ib5z3elq.txt	./txt/cord-006279-ib5z3elq.txt