id author title date pages extension mime words sentences flesch summary cache txt cord-261608-4sjlg0p0 Trejo-Paredes, Camila COVID-19-INDUCED LIVER INJURY: A CLINICAL DISTRACTION? 2020-10-31 .txt text/plain 455 42 45 title: COVID-19-INDUCED LIVER INJURY: A CLINICAL DISTRACTION? His hospital course was also complicated by acute renal failure requiring renal replacement therapy, coagulopathy, and encephalopathy which coincided with liver injury trailing behind the peak of inflammatory markers. Emerging data support the hypothesis that liver injury in COVID-19 is often the result of SARS-CoV-2 directly binding to ACE2+ cholangiocytes, leading to cholangiohepatitis. In addition, cytokine storm may further exacerbate the hepatic injury in COVID-19 (2). Hepatic congestion in ventilated patients, shock liver and particularly, drug-induced liver injury (DILI) remains an important consideration in COVID-19 patients. CONCLUSIONS: COVID-19 induced viral hepatitis is now being increasingly identified as a self-resolving complication and the physician should be mindful of it and in the right setting, it may only be a clinical distraction. We should be cognizant of other potential causes of liver injury in COVID-19 patients like concurrent infection, sepsis-induced and DILI. Liver injury in COVID-19: The current evidence COVID-19 and the liver: little cause for concern. ./cache/cord-261608-4sjlg0p0.txt ./txt/cord-261608-4sjlg0p0.txt