id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-018225-dozmy3lb	Hawker, Felicity H.	The liver in critical illness	2008		.txt	text/plain	6814	319	45	The paper by Harrison and co-workers, again from the King's Liver Unit, investigates the effects of n-acetylcysteine in patients with acute liver failure, and the findings of this study have resulted in widespread use of this agent in this setting. The incidence of hypoxic hepatitis was prospectively studied for 1 year in a group of high-risk patients suffering from low cardiac output in a coronary care unit. In intensive care patients, a rapid decrease in MEGX test values is associated with increased risk of developing multiple organ failure, and a poor outcome, and consequently may have a role in investigation of the role of the liver in the multiple organ failure syndrome. We studied the effect of acetylcysteine on systemic hemodynamics and oxygen transport in 12 patients with acetaminophen-induced fulminant hepatic failure, and 8 patients with acute liver failure from other causes. The increase in oxygen delivery and consumption in response to acetylcysteine may account for its beneficial effect on survival in patients with fulminant hepatic failure induced by acetaminophen.	./cache/cord-018225-dozmy3lb.txt	./txt/cord-018225-dozmy3lb.txt