id	sid	tid	token	lemma	pos
cord-017161-lcqrd4v0	1	1	key	key	JJ
cord-017161-lcqrd4v0	1	2	:	:	:
cord-017161-lcqrd4v0	1	3	cord-017161-lcqrd4v0	cord-017161-lcqrd4v0	NN
cord-017161-lcqrd4v0	1	4	authors	author	NNS
cord-017161-lcqrd4v0	1	5	:	:	:
cord-017161-lcqrd4v0	1	6	Eleftheriou	Eleftheriou	NNP
cord-017161-lcqrd4v0	1	7	,	,	,
cord-017161-lcqrd4v0	1	8	Despina	Despina	NNP
cord-017161-lcqrd4v0	1	9	;	;	:
cord-017161-lcqrd4v0	1	10	Brogan	Brogan	NNP
cord-017161-lcqrd4v0	1	11	,	,	,
cord-017161-lcqrd4v0	2	1	Paul	Paul	NNP
cord-017161-lcqrd4v0	2	2	A.	a.	NN
cord-017161-lcqrd4v0	2	3	title	title	NN
cord-017161-lcqrd4v0	2	4	:	:	:
cord-017161-lcqrd4v0	3	1	The	the	DT
cord-017161-lcqrd4v0	3	2	Molecular	Molecular	NNP
cord-017161-lcqrd4v0	3	3	Biology	Biology	NNP
cord-017161-lcqrd4v0	3	4	and	and	CC
cord-017161-lcqrd4v0	3	5	Treatment	Treatment	NNP
cord-017161-lcqrd4v0	3	6	of	of	IN
cord-017161-lcqrd4v0	3	7	Systemic	Systemic	NNP
cord-017161-lcqrd4v0	3	8	Vasculitis	Vasculitis	NNP
cord-017161-lcqrd4v0	3	9	in	in	IN
cord-017161-lcqrd4v0	3	10	Children	Children	NNP
cord-017161-lcqrd4v0	3	11	date	date	NN
cord-017161-lcqrd4v0	3	12	:	:	:
cord-017161-lcqrd4v0	3	13	2012	2012	CD
cord-017161-lcqrd4v0	3	14	-	-	HYPH
cord-017161-lcqrd4v0	3	15	02	02	CD
cord-017161-lcqrd4v0	3	16	-	-	SYM
cord-017161-lcqrd4v0	3	17	23	23	CD
cord-017161-lcqrd4v0	3	18	journal	journal	NN
cord-017161-lcqrd4v0	3	19	:	:	:
cord-017161-lcqrd4v0	4	1	Molecular	molecular	JJ
cord-017161-lcqrd4v0	4	2	and	and	CC
cord-017161-lcqrd4v0	4	3	Translational	Translational	NNP
cord-017161-lcqrd4v0	4	4	Vascular	Vascular	NNP
cord-017161-lcqrd4v0	4	5	Medicine	Medicine	NNP
cord-017161-lcqrd4v0	4	6	DOI	doi	NN
cord-017161-lcqrd4v0	4	7	:	:	:
cord-017161-lcqrd4v0	4	8	10.1007/978	10.1007/978	CD
cord-017161-lcqrd4v0	4	9	-	-	HYPH
cord-017161-lcqrd4v0	4	10	1	1	CD
cord-017161-lcqrd4v0	4	11	-	-	HYPH
cord-017161-lcqrd4v0	4	12	61779	61779	CD
cord-017161-lcqrd4v0	4	13	-	-	HYPH
cord-017161-lcqrd4v0	4	14	906	906	CD
cord-017161-lcqrd4v0	4	15	-	-	HYPH
cord-017161-lcqrd4v0	4	16	8_2	8_2	CD
cord-017161-lcqrd4v0	4	17	sha	sha	NN
cord-017161-lcqrd4v0	4	18	:	:	:
cord-017161-lcqrd4v0	4	19	14c4936378b78d5039dc318e1bc6d2dd3044b014	14c4936378b78d5039dc318e1bc6d2dd3044b014	CD
cord-017161-lcqrd4v0	4	20	doc_id	doc_id	CD
cord-017161-lcqrd4v0	4	21	:	:	:
cord-017161-lcqrd4v0	4	22	17161	17161	CD
cord-017161-lcqrd4v0	4	23	cord_uid	cord_uid	NNS
cord-017161-lcqrd4v0	4	24	:	:	:
cord-017161-lcqrd4v0	5	1	lcqrd4v0	lcqrd4v0	NNP
cord-017161-lcqrd4v0	5	2	Primary	primary	JJ
cord-017161-lcqrd4v0	5	3	systemic	systemic	JJ
cord-017161-lcqrd4v0	5	4	vasculitides	vasculitide	NNS
cord-017161-lcqrd4v0	5	5	are	be	VBP
cord-017161-lcqrd4v0	5	6	rare	rare	JJ
cord-017161-lcqrd4v0	5	7	in	in	IN
cord-017161-lcqrd4v0	5	8	childhood	childhood	NN
cord-017161-lcqrd4v0	5	9	but	but	CC
cord-017161-lcqrd4v0	5	10	are	be	VBP
cord-017161-lcqrd4v0	5	11	associated	associate	VBN
cord-017161-lcqrd4v0	5	12	with	with	IN
cord-017161-lcqrd4v0	5	13	significant	significant	JJ
cord-017161-lcqrd4v0	5	14	morbidity	morbidity	NN
cord-017161-lcqrd4v0	5	15	and	and	CC
cord-017161-lcqrd4v0	5	16	mortality	mortality	NN
cord-017161-lcqrd4v0	5	17	.	.	.
cord-017161-lcqrd4v0	6	1	The	the	DT
cord-017161-lcqrd4v0	6	2	cause	cause	NN
cord-017161-lcqrd4v0	6	3	of	of	IN
cord-017161-lcqrd4v0	6	4	the	the	DT
cord-017161-lcqrd4v0	6	5	majority	majority	NN
cord-017161-lcqrd4v0	6	6	of	of	IN
cord-017161-lcqrd4v0	6	7	vasculitides	vasculitide	NNS
cord-017161-lcqrd4v0	6	8	is	be	VBZ
cord-017161-lcqrd4v0	6	9	unknown	unknown	JJ
cord-017161-lcqrd4v0	6	10	,	,	,
cord-017161-lcqrd4v0	6	11	although	although	IN
cord-017161-lcqrd4v0	6	12	it	-PRON-	PRP
cord-017161-lcqrd4v0	6	13	is	be	VBZ
cord-017161-lcqrd4v0	6	14	likely	likely	JJ
cord-017161-lcqrd4v0	6	15	that	that	IN
cord-017161-lcqrd4v0	6	16	a	a	DT
cord-017161-lcqrd4v0	6	17	complex	complex	JJ
cord-017161-lcqrd4v0	6	18	interaction	interaction	NN
cord-017161-lcqrd4v0	6	19	between	between	IN
cord-017161-lcqrd4v0	6	20	environmental	environmental	JJ
cord-017161-lcqrd4v0	6	21	factors	factor	NNS
cord-017161-lcqrd4v0	6	22	,	,	,
cord-017161-lcqrd4v0	6	23	such	such	JJ
cord-017161-lcqrd4v0	6	24	as	as	IN
cord-017161-lcqrd4v0	6	25	infections	infection	NNS
cord-017161-lcqrd4v0	6	26	and	and	CC
cord-017161-lcqrd4v0	6	27	inherited	inherit	VBD
cord-017161-lcqrd4v0	6	28	host	host	NN
cord-017161-lcqrd4v0	6	29	responses	response	NNS
cord-017161-lcqrd4v0	6	30	,	,	,
cord-017161-lcqrd4v0	6	31	triggers	trigger	VBZ
cord-017161-lcqrd4v0	6	32	the	the	DT
cord-017161-lcqrd4v0	6	33	disease	disease	NN
cord-017161-lcqrd4v0	6	34	and	and	CC
cord-017161-lcqrd4v0	6	35	determines	determine	VBZ
cord-017161-lcqrd4v0	6	36	the	the	DT
cord-017161-lcqrd4v0	6	37	vasculitis	vasculitis	JJ
cord-017161-lcqrd4v0	6	38	phenotype	phenotype	NN
cord-017161-lcqrd4v0	6	39	.	.	.
cord-017161-lcqrd4v0	7	1	Several	several	JJ
cord-017161-lcqrd4v0	7	2	genetic	genetic	JJ
cord-017161-lcqrd4v0	7	3	polymorphisms	polymorphism	NNS
cord-017161-lcqrd4v0	7	4	in	in	IN
cord-017161-lcqrd4v0	7	5	vasculitides	vasculitide	NNS
cord-017161-lcqrd4v0	7	6	have	have	VBP
cord-017161-lcqrd4v0	7	7	now	now	RB
cord-017161-lcqrd4v0	7	8	been	be	VBN
cord-017161-lcqrd4v0	7	9	described	describe	VBN
cord-017161-lcqrd4v0	7	10	,	,	,
cord-017161-lcqrd4v0	7	11	which	which	WDT
cord-017161-lcqrd4v0	7	12	may	may	MD
cord-017161-lcqrd4v0	7	13	be	be	VB
cord-017161-lcqrd4v0	7	14	relevant	relevant	JJ
cord-017161-lcqrd4v0	7	15	in	in	IN
cord-017161-lcqrd4v0	7	16	terms	term	NNS
cord-017161-lcqrd4v0	7	17	of	of	IN
cord-017161-lcqrd4v0	7	18	disease	disease	NN
cord-017161-lcqrd4v0	7	19	predisposition	predisposition	NN
cord-017161-lcqrd4v0	7	20	or	or	CC
cord-017161-lcqrd4v0	7	21	development	development	NN
cord-017161-lcqrd4v0	7	22	of	of	IN
cord-017161-lcqrd4v0	7	23	disease	disease	NN
cord-017161-lcqrd4v0	7	24	complications	complication	NNS
cord-017161-lcqrd4v0	7	25	.	.	.
cord-017161-lcqrd4v0	8	1	Treatment	treatment	NN
cord-017161-lcqrd4v0	8	2	regimens	regimen	NNS
cord-017161-lcqrd4v0	8	3	continue	continue	VBP
cord-017161-lcqrd4v0	8	4	to	to	TO
cord-017161-lcqrd4v0	8	5	improve	improve	VB
cord-017161-lcqrd4v0	8	6	with	with	IN
cord-017161-lcqrd4v0	8	7	the	the	DT
cord-017161-lcqrd4v0	8	8	use	use	NN
cord-017161-lcqrd4v0	8	9	of	of	IN
cord-017161-lcqrd4v0	8	10	different	different	JJ
cord-017161-lcqrd4v0	8	11	immunosuppressive	immunosuppressive	JJ
cord-017161-lcqrd4v0	8	12	medications	medication	NNS
cord-017161-lcqrd4v0	8	13	and	and	CC
cord-017161-lcqrd4v0	8	14	newer	new	JJR
cord-017161-lcqrd4v0	8	15	therapeutic	therapeutic	JJ
cord-017161-lcqrd4v0	8	16	approaches	approach	NNS
cord-017161-lcqrd4v0	8	17	such	such	JJ
cord-017161-lcqrd4v0	8	18	as	as	IN
cord-017161-lcqrd4v0	8	19	biologic	biologic	JJ
cord-017161-lcqrd4v0	8	20	agents	agent	NNS
cord-017161-lcqrd4v0	8	21	.	.	.
cord-017161-lcqrd4v0	9	1	This	this	DT
cord-017161-lcqrd4v0	9	2	chapter	chapter	NN
cord-017161-lcqrd4v0	9	3	reviews	review	VBZ
cord-017161-lcqrd4v0	9	4	recent	recent	JJ
cord-017161-lcqrd4v0	9	5	studies	study	NNS
cord-017161-lcqrd4v0	9	6	shedding	shed	VBG
cord-017161-lcqrd4v0	9	7	light	light	NN
cord-017161-lcqrd4v0	9	8	on	on	IN
cord-017161-lcqrd4v0	9	9	the	the	DT
cord-017161-lcqrd4v0	9	10	pathogenesis	pathogenesis	NN
cord-017161-lcqrd4v0	9	11	of	of	IN
cord-017161-lcqrd4v0	9	12	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	9	13	with	with	IN
cord-017161-lcqrd4v0	9	14	emphasis	emphasis	NN
cord-017161-lcqrd4v0	9	15	on	on	IN
cord-017161-lcqrd4v0	9	16	molecular	molecular	JJ
cord-017161-lcqrd4v0	9	17	biology	biology	NN
cord-017161-lcqrd4v0	9	18	where	where	WRB
cord-017161-lcqrd4v0	9	19	known	know	VBN
cord-017161-lcqrd4v0	9	20	,	,	,
cord-017161-lcqrd4v0	9	21	and	and	CC
cord-017161-lcqrd4v0	9	22	summarizes	summarize	VBZ
cord-017161-lcqrd4v0	9	23	current	current	JJ
cord-017161-lcqrd4v0	9	24	treatment	treatment	NN
cord-017161-lcqrd4v0	9	25	strategies	strategy	NNS
cord-017161-lcqrd4v0	9	26	.	.	.
cord-017161-lcqrd4v0	10	1	We	-PRON-	PRP
cord-017161-lcqrd4v0	10	2	discuss	discuss	VBP
cord-017161-lcqrd4v0	10	3	new	new	JJ
cord-017161-lcqrd4v0	10	4	emerging	emerge	VBG
cord-017161-lcqrd4v0	10	5	challenges	challenge	NNS
cord-017161-lcqrd4v0	10	6	particularly	particularly	RB
cord-017161-lcqrd4v0	10	7	with	with	IN
cord-017161-lcqrd4v0	10	8	respect	respect	NN
cord-017161-lcqrd4v0	10	9	to	to	IN
cord-017161-lcqrd4v0	10	10	the	the	DT
cord-017161-lcqrd4v0	10	11	long	long	JJ
cord-017161-lcqrd4v0	10	12	-	-	HYPH
cord-017161-lcqrd4v0	10	13	term	term	NN
cord-017161-lcqrd4v0	10	14	cardiovascular	cardiovascular	JJ
cord-017161-lcqrd4v0	10	15	morbidity	morbidity	NN
cord-017161-lcqrd4v0	10	16	for	for	IN
cord-017161-lcqrd4v0	10	17	children	child	NNS
cord-017161-lcqrd4v0	10	18	with	with	IN
cord-017161-lcqrd4v0	10	19	systemic	systemic	JJ
cord-017161-lcqrd4v0	10	20	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	10	21	and	and	CC
cord-017161-lcqrd4v0	10	22	emphasize	emphasize	VB
cord-017161-lcqrd4v0	10	23	the	the	DT
cord-017161-lcqrd4v0	10	24	importance	importance	NN
cord-017161-lcqrd4v0	10	25	of	of	IN
cord-017161-lcqrd4v0	10	26	future	future	JJ
cord-017161-lcqrd4v0	10	27	international	international	JJ
cord-017161-lcqrd4v0	10	28	multicenter	multicenter	JJ
cord-017161-lcqrd4v0	10	29	collaborative	collaborative	NN
cord-017161-lcqrd4v0	10	30	studies	study	NNS
cord-017161-lcqrd4v0	10	31	to	to	TO
cord-017161-lcqrd4v0	10	32	further	further	RB
cord-017161-lcqrd4v0	10	33	increase	increase	VB
cord-017161-lcqrd4v0	10	34	and	and	CC
cord-017161-lcqrd4v0	10	35	standardize	standardize	VB
cord-017161-lcqrd4v0	10	36	the	the	DT
cord-017161-lcqrd4v0	10	37	scientific	scientific	JJ
cord-017161-lcqrd4v0	10	38	base	base	NN
cord-017161-lcqrd4v0	10	39	investigating	investigate	VBG
cord-017161-lcqrd4v0	10	40	and	and	CC
cord-017161-lcqrd4v0	10	41	treating	treat	VBG
cord-017161-lcqrd4v0	10	42	childhood	childhood	NN
cord-017161-lcqrd4v0	10	43	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	10	44	.	.	.
cord-017161-lcqrd4v0	11	1	Systemic	systemic	JJ
cord-017161-lcqrd4v0	11	2	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	11	3	is	be	VBZ
cord-017161-lcqrd4v0	11	4	characterized	characterize	VBN
cord-017161-lcqrd4v0	11	5	by	by	IN
cord-017161-lcqrd4v0	11	6	blood	blood	NN
cord-017161-lcqrd4v0	11	7	vessel	vessel	NN
cord-017161-lcqrd4v0	11	8	in	in	IN
cord-017161-lcqrd4v0	11	9	fl	fl	NNP
cord-017161-lcqrd4v0	11	10	ammation	ammation	NNP
cord-017161-lcqrd4v0	11	11	,	,	,
cord-017161-lcqrd4v0	11	12	which	which	WDT
cord-017161-lcqrd4v0	11	13	may	may	MD
cord-017161-lcqrd4v0	11	14	lead	lead	VB
cord-017161-lcqrd4v0	11	15	to	to	IN
cord-017161-lcqrd4v0	11	16	tissue	tissue	NN
cord-017161-lcqrd4v0	11	17	injury	injury	NN
cord-017161-lcqrd4v0	11	18	from	from	IN
cord-017161-lcqrd4v0	11	19	vascular	vascular	JJ
cord-017161-lcqrd4v0	11	20	stenosis	stenosis	NN
cord-017161-lcqrd4v0	11	21	,	,	,
cord-017161-lcqrd4v0	11	22	occlusion	occlusion	NN
cord-017161-lcqrd4v0	11	23	,	,	,
cord-017161-lcqrd4v0	11	24	aneurysm	aneurysm	NN
cord-017161-lcqrd4v0	11	25	or	or	CC
cord-017161-lcqrd4v0	11	26	rupture	rupture	NN
cord-017161-lcqrd4v0	11	27	[	[	-LRB-
cord-017161-lcqrd4v0	11	28	1	1	CD
cord-017161-lcqrd4v0	11	29	]	]	-RRB-
cord-017161-lcqrd4v0	11	30	.	.	.
cord-017161-lcqrd4v0	12	1	Apart	apart	RB
cord-017161-lcqrd4v0	12	2	from	from	IN
cord-017161-lcqrd4v0	12	3	relatively	relatively	RB
cord-017161-lcqrd4v0	12	4	common	common	JJ
cord-017161-lcqrd4v0	12	5	vasculitides	vasculitide	NNS
cord-017161-lcqrd4v0	12	6	such	such	JJ
cord-017161-lcqrd4v0	12	7	as	as	IN
cord-017161-lcqrd4v0	12	8	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	12	9	-	-	HYPH
cord-017161-lcqrd4v0	12	10	Schönlein	Schönlein	NNP
cord-017161-lcqrd4v0	12	11	Purpura	Purpura	NNP
cord-017161-lcqrd4v0	12	12	(	(	-LRB-
cord-017161-lcqrd4v0	12	13	HSP	HSP	NNP
cord-017161-lcqrd4v0	12	14	)	)	-RRB-
cord-017161-lcqrd4v0	12	15	and	and	CC
cord-017161-lcqrd4v0	12	16	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	12	17	disease	disease	NN
cord-017161-lcqrd4v0	12	18	(	(	-LRB-
cord-017161-lcqrd4v0	12	19	KD	KD	NNP
cord-017161-lcqrd4v0	12	20	)	)	-RRB-
cord-017161-lcqrd4v0	12	21	,	,	,
cord-017161-lcqrd4v0	12	22	most	most	JJS
cord-017161-lcqrd4v0	12	23	of	of	IN
cord-017161-lcqrd4v0	12	24	the	the	DT
cord-017161-lcqrd4v0	12	25	primary	primary	JJ
cord-017161-lcqrd4v0	12	26	vasculitic	vasculitic	JJ
cord-017161-lcqrd4v0	12	27	syndromes	syndrome	NNS
cord-017161-lcqrd4v0	12	28	are	be	VBP
cord-017161-lcqrd4v0	12	29	rare	rare	JJ
cord-017161-lcqrd4v0	12	30	in	in	IN
cord-017161-lcqrd4v0	12	31	childhood	childhood	NN
cord-017161-lcqrd4v0	12	32	,	,	,
cord-017161-lcqrd4v0	12	33	but	but	CC
cord-017161-lcqrd4v0	12	34	when	when	WRB
cord-017161-lcqrd4v0	12	35	present	present	JJ
cord-017161-lcqrd4v0	12	36	are	be	VBP
cord-017161-lcqrd4v0	12	37	associated	associate	VBN
cord-017161-lcqrd4v0	12	38	with	with	IN
cord-017161-lcqrd4v0	12	39	signi	signi	NNP
cord-017161-lcqrd4v0	12	40	fi	fi	NNP
cord-017161-lcqrd4v0	12	41	ca	can	MD
cord-017161-lcqrd4v0	12	42	nt	not	RB
cord-017161-lcqrd4v0	12	43	morbidity	morbidity	NN
cord-017161-lcqrd4v0	12	44	and	and	CC
cord-017161-lcqrd4v0	12	45	mortality	mortality	NN
cord-017161-lcqrd4v0	12	46	[	[	-LRB-
cord-017161-lcqrd4v0	12	47	2	2	CD
cord-017161-lcqrd4v0	12	48	,	,	,
cord-017161-lcqrd4v0	12	49	3	3	CD
cord-017161-lcqrd4v0	12	50	]	]	-RRB-
cord-017161-lcqrd4v0	12	51	.	.	.
cord-017161-lcqrd4v0	13	1	The	the	DT
cord-017161-lcqrd4v0	13	2	cause	cause	NN
cord-017161-lcqrd4v0	13	3	of	of	IN
cord-017161-lcqrd4v0	13	4	the	the	DT
cord-017161-lcqrd4v0	13	5	majority	majority	NN
cord-017161-lcqrd4v0	13	6	of	of	IN
cord-017161-lcqrd4v0	13	7	childhood	childhood	NN
cord-017161-lcqrd4v0	13	8	vasculitides	vasculitide	NNS
cord-017161-lcqrd4v0	13	9	is	be	VBZ
cord-017161-lcqrd4v0	13	10	unknown	unknown	JJ
cord-017161-lcqrd4v0	13	11	,	,	,
cord-017161-lcqrd4v0	13	12	although	although	IN
cord-017161-lcqrd4v0	13	13	it	-PRON-	PRP
cord-017161-lcqrd4v0	13	14	is	be	VBZ
cord-017161-lcqrd4v0	13	15	likely	likely	JJ
cord-017161-lcqrd4v0	13	16	that	that	IN
cord-017161-lcqrd4v0	13	17	a	a	DT
cord-017161-lcqrd4v0	13	18	complex	complex	JJ
cord-017161-lcqrd4v0	13	19	interaction	interaction	NN
cord-017161-lcqrd4v0	13	20	between	between	IN
cord-017161-lcqrd4v0	13	21	environmental	environmental	JJ
cord-017161-lcqrd4v0	13	22	factors	factor	NNS
cord-017161-lcqrd4v0	13	23	,	,	,
cord-017161-lcqrd4v0	13	24	such	such	JJ
cord-017161-lcqrd4v0	13	25	as	as	IN
cord-017161-lcqrd4v0	13	26	infections	infection	NNS
cord-017161-lcqrd4v0	13	27	and	and	CC
cord-017161-lcqrd4v0	13	28	inherited	inherit	VBD
cord-017161-lcqrd4v0	13	29	host	host	NN
cord-017161-lcqrd4v0	13	30	responses	response	NNS
cord-017161-lcqrd4v0	13	31	,	,	,
cord-017161-lcqrd4v0	13	32	triggers	trigger	VBZ
cord-017161-lcqrd4v0	13	33	the	the	DT
cord-017161-lcqrd4v0	13	34	disease	disease	NN
cord-017161-lcqrd4v0	13	35	and	and	CC
cord-017161-lcqrd4v0	13	36	determines	determine	VBZ
cord-017161-lcqrd4v0	13	37	the	the	DT
cord-017161-lcqrd4v0	13	38	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	13	39	phenotype	phenotype	NN
cord-017161-lcqrd4v0	13	40	[	[	-LRB-
cord-017161-lcqrd4v0	13	41	4	4	CD
cord-017161-lcqrd4v0	13	42	]	]	-RRB-
cord-017161-lcqrd4v0	13	43	.	.	.
cord-017161-lcqrd4v0	14	1	This	this	DT
cord-017161-lcqrd4v0	14	2	chapter	chapter	NN
cord-017161-lcqrd4v0	14	3	summarizes	summarize	VBZ
cord-017161-lcqrd4v0	14	4	the	the	DT
cord-017161-lcqrd4v0	14	5	fi	fi	NNP
cord-017161-lcqrd4v0	14	6	ndings	nding	NNS
cord-017161-lcqrd4v0	14	7	of	of	IN
cord-017161-lcqrd4v0	14	8	recent	recent	JJ
cord-017161-lcqrd4v0	14	9	studies	study	NNS
cord-017161-lcqrd4v0	14	10	relating	relate	VBG
cord-017161-lcqrd4v0	14	11	to	to	IN
cord-017161-lcqrd4v0	14	12	the	the	DT
cord-017161-lcqrd4v0	14	13	pathogenesis	pathogenesis	NN
cord-017161-lcqrd4v0	14	14	of	of	IN
cord-017161-lcqrd4v0	14	15	systemic	systemic	JJ
cord-017161-lcqrd4v0	14	16	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	14	17	,	,	,
cord-017161-lcqrd4v0	14	18	and	and	CC
cord-017161-lcqrd4v0	14	19	considers	consider	VBZ
cord-017161-lcqrd4v0	14	20	HSP	HSP	NNP
cord-017161-lcqrd4v0	14	21	,	,	,
cord-017161-lcqrd4v0	14	22	KD	KD	NNP
cord-017161-lcqrd4v0	14	23	,	,	,
cord-017161-lcqrd4v0	14	24	antineutrophil	antineutrophil	NNP
cord-017161-lcqrd4v0	14	25	cytoplasmic	cytoplasmic	JJ
cord-017161-lcqrd4v0	14	26	antibodies	antibody	NNS
cord-017161-lcqrd4v0	14	27	(	(	-LRB-
cord-017161-lcqrd4v0	14	28	ANCAs)-associated	ancas)-associate	VBN
cord-017161-lcqrd4v0	14	29	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	14	30	,	,	,
cord-017161-lcqrd4v0	14	31	polyarteritis	polyarteritis	NN
cord-017161-lcqrd4v0	14	32	nodosa	nodosa	NNP
cord-017161-lcqrd4v0	14	33	and	and	CC
cord-017161-lcqrd4v0	14	34	Takayasu	Takayasu	NNP
cord-017161-lcqrd4v0	14	35	arteritis	arteritis	NN
cord-017161-lcqrd4v0	14	36	(	(	-LRB-
cord-017161-lcqrd4v0	14	37	TA	TA	NNP
cord-017161-lcqrd4v0	14	38	)	)	-RRB-
cord-017161-lcqrd4v0	14	39	.	.	.
cord-017161-lcqrd4v0	15	1	Rarer	rarer	JJ
cord-017161-lcqrd4v0	15	2	forms	form	NNS
cord-017161-lcqrd4v0	15	3	of	of	IN
cord-017161-lcqrd4v0	15	4	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	15	5	are	be	VBP
cord-017161-lcqrd4v0	15	6	beyond	beyond	IN
cord-017161-lcqrd4v0	15	7	the	the	DT
cord-017161-lcqrd4v0	15	8	scope	scope	NN
cord-017161-lcqrd4v0	15	9	of	of	IN
cord-017161-lcqrd4v0	15	10	this	this	DT
cord-017161-lcqrd4v0	15	11	chapter	chapter	NN
cord-017161-lcqrd4v0	15	12	,	,	,
cord-017161-lcqrd4v0	15	13	and	and	CC
cord-017161-lcqrd4v0	15	14	the	the	DT
cord-017161-lcqrd4v0	15	15	reader	reader	NN
cord-017161-lcqrd4v0	15	16	is	be	VBZ
cord-017161-lcqrd4v0	15	17	referred	refer	VBN
cord-017161-lcqrd4v0	15	18	elsewhere	elsewhere	RB
cord-017161-lcqrd4v0	15	19	[	[	-LRB-
cord-017161-lcqrd4v0	15	20	5	5	CD
cord-017161-lcqrd4v0	15	21	]	]	-RRB-
cord-017161-lcqrd4v0	15	22	.	.	.
cord-017161-lcqrd4v0	16	1	In	in	IN
cord-017161-lcqrd4v0	16	2	addition	addition	NN
cord-017161-lcqrd4v0	16	3	,	,	,
cord-017161-lcqrd4v0	16	4	we	-PRON-	PRP
cord-017161-lcqrd4v0	16	5	discuss	discuss	VBP
cord-017161-lcqrd4v0	16	6	current	current	JJ
cord-017161-lcqrd4v0	16	7	therapeutic	therapeutic	JJ
cord-017161-lcqrd4v0	16	8	approaches	approach	NNS
cord-017161-lcqrd4v0	16	9	and	and	CC
cord-017161-lcqrd4v0	16	10	ongoing	ongoing	JJ
cord-017161-lcqrd4v0	16	11	challenges	challenge	NNS
cord-017161-lcqrd4v0	16	12	in	in	IN
cord-017161-lcqrd4v0	16	13	the	the	DT
cord-017161-lcqrd4v0	16	14	fi	fi	NNP
cord-017161-lcqrd4v0	16	15	eld	eld	NN
cord-017161-lcqrd4v0	16	16	of	of	IN
cord-017161-lcqrd4v0	16	17	paediatric	paediatric	JJ
cord-017161-lcqrd4v0	16	18	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	16	19	research	research	NN
cord-017161-lcqrd4v0	16	20	.	.	.
cord-017161-lcqrd4v0	17	1	Modi	Modi	NNP
cord-017161-lcqrd4v0	17	2	fi	fi	IN
cord-017161-lcqrd4v0	17	3	cations	cation	NNS
cord-017161-lcqrd4v0	17	4	of	of	IN
cord-017161-lcqrd4v0	17	5	the	the	DT
cord-017161-lcqrd4v0	17	6	classi	classi	NNP
cord-017161-lcqrd4v0	17	7	fi	fi	NNP
cord-017161-lcqrd4v0	17	8	cation	cation	NNP
cord-017161-lcqrd4v0	17	9	criteria	criterion	NNS
cord-017161-lcqrd4v0	17	10	de	de	NNP
cord-017161-lcqrd4v0	17	11	fi	fi	NNP
cord-017161-lcqrd4v0	17	12	ning	ning	NNP
cord-017161-lcqrd4v0	17	13	HSP	HSP	NNP
cord-017161-lcqrd4v0	17	14	described	describe	VBN
cord-017161-lcqrd4v0	17	15	by	by	IN
cord-017161-lcqrd4v0	17	16	Ozen	Ozen	NNP
cord-017161-lcqrd4v0	17	17	et	et	NNP
cord-017161-lcqrd4v0	17	18	al	al	NNP
cord-017161-lcqrd4v0	17	19	.	.	.
cord-017161-lcqrd4v0	18	1	in	in	IN
cord-017161-lcqrd4v0	18	2	2005	2005	CD
cord-017161-lcqrd4v0	18	3	[	[	-LRB-
cord-017161-lcqrd4v0	18	4	7	7	CD
cord-017161-lcqrd4v0	18	5	]	]	-RRB-
cord-017161-lcqrd4v0	18	6	have	have	VBP
cord-017161-lcqrd4v0	18	7	recently	recently	RB
cord-017161-lcqrd4v0	18	8	been	be	VBN
cord-017161-lcqrd4v0	18	9	made	make	VBN
cord-017161-lcqrd4v0	18	10	following	follow	VBG
cord-017161-lcqrd4v0	18	11	a	a	DT
cord-017161-lcqrd4v0	18	12	formal	formal	JJ
cord-017161-lcqrd4v0	18	13	validation	validation	NN
cord-017161-lcqrd4v0	18	14	study	study	NN
cord-017161-lcqrd4v0	18	15	[	[	-LRB-
cord-017161-lcqrd4v0	18	16	8	8	CD
cord-017161-lcqrd4v0	18	17	]	]	-RRB-
cord-017161-lcqrd4v0	18	18	.	.	.
cord-017161-lcqrd4v0	19	1	According	accord	VBG
cord-017161-lcqrd4v0	19	2	to	to	IN
cord-017161-lcqrd4v0	19	3	the	the	DT
cord-017161-lcqrd4v0	19	4	new	new	JJ
cord-017161-lcqrd4v0	19	5	EULAR	EULAR	NNP
cord-017161-lcqrd4v0	19	6	/	/	SYM
cord-017161-lcqrd4v0	19	7	PRINTO	PRINTO	NNP
cord-017161-lcqrd4v0	19	8	/	/	SYM
cord-017161-lcqrd4v0	19	9	PRES	PRES	NNP
cord-017161-lcqrd4v0	19	10	de	de	NNP
cord-017161-lcqrd4v0	19	11	fi	fi	NNP
cord-017161-lcqrd4v0	19	12	nition	nition	NN
cord-017161-lcqrd4v0	19	13	,	,	,
cord-017161-lcqrd4v0	19	14	a	a	DT
cord-017161-lcqrd4v0	19	15	patient	patient	NN
cord-017161-lcqrd4v0	19	16	is	be	VBZ
cord-017161-lcqrd4v0	19	17	classi	classi	FW
cord-017161-lcqrd4v0	19	18	fi	fi	NNP
cord-017161-lcqrd4v0	19	19	ed	ed	NNP
cord-017161-lcqrd4v0	19	20	as	as	IN
cord-017161-lcqrd4v0	19	21	having	have	VBG
cord-017161-lcqrd4v0	19	22	HSP	HSP	NNP
cord-017161-lcqrd4v0	19	23	in	in	IN
cord-017161-lcqrd4v0	19	24	the	the	DT
cord-017161-lcqrd4v0	19	25	presence	presence	NN
cord-017161-lcqrd4v0	19	26	of	of	IN
cord-017161-lcqrd4v0	19	27	purpura	purpura	NN
cord-017161-lcqrd4v0	19	28	or	or	CC
cord-017161-lcqrd4v0	19	29	petechie	petechie	NN
cord-017161-lcqrd4v0	19	30	with	with	IN
cord-017161-lcqrd4v0	19	31	lower	low	JJR
cord-017161-lcqrd4v0	19	32	limb	limb	NN
cord-017161-lcqrd4v0	19	33	predominance	predominance	NN
cord-017161-lcqrd4v0	19	34	(	(	-LRB-
cord-017161-lcqrd4v0	19	35	mandatory	mandatory	JJ
cord-017161-lcqrd4v0	19	36	criterion	criterion	NN
cord-017161-lcqrd4v0	19	37	)	)	-RRB-
cord-017161-lcqrd4v0	19	38	plus	plus	CC
cord-017161-lcqrd4v0	19	39	one	one	CD
cord-017161-lcqrd4v0	19	40	out	out	IN
cord-017161-lcqrd4v0	19	41	of	of	IN
cord-017161-lcqrd4v0	19	42	four	four	CD
cord-017161-lcqrd4v0	19	43	of	of	IN
cord-017161-lcqrd4v0	19	44	the	the	DT
cord-017161-lcqrd4v0	19	45	following	follow	VBG
cord-017161-lcqrd4v0	19	46	criteria	criterion	NNS
cord-017161-lcqrd4v0	19	47	[	[	-LRB-
cord-017161-lcqrd4v0	19	48	8	8	CD
cord-017161-lcqrd4v0	19	49	]	]	-RRB-
cord-017161-lcqrd4v0	19	50	:	:	:
cord-017161-lcqrd4v0	19	51	1	1	LS
cord-017161-lcqrd4v0	19	52	.	.	.
cord-017161-lcqrd4v0	20	1	Abdominal	abdominal	JJ
cord-017161-lcqrd4v0	20	2	pain	pain	NN
cord-017161-lcqrd4v0	20	3	2	2	CD
cord-017161-lcqrd4v0	20	4	.	.	.
cord-017161-lcqrd4v0	21	1	Histopathology	Histopathology	NNP
cord-017161-lcqrd4v0	21	2	showing	show	VBG
cord-017161-lcqrd4v0	21	3	typical	typical	JJ
cord-017161-lcqrd4v0	21	4	leucocytoclastic	leucocytoclastic	JJ
cord-017161-lcqrd4v0	21	5	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	21	6	with	with	IN
cord-017161-lcqrd4v0	21	7	predominant	predominant	JJ
cord-017161-lcqrd4v0	21	8	IgA	IgA	NNP
cord-017161-lcqrd4v0	21	9	deposit	deposit	NN
cord-017161-lcqrd4v0	21	10	or	or	CC
cord-017161-lcqrd4v0	21	11	proliferative	proliferative	JJ
cord-017161-lcqrd4v0	21	12	glomerulonephritis	glomerulonephritis	NN
cord-017161-lcqrd4v0	21	13	with	with	IN
cord-017161-lcqrd4v0	21	14	predominant	predominant	JJ
cord-017161-lcqrd4v0	21	15	IgA	IgA	NNP
cord-017161-lcqrd4v0	21	16	deposit	deposit	NNP
cord-017161-lcqrd4v0	21	17	3	3	CD
cord-017161-lcqrd4v0	21	18	.	.	.
cord-017161-lcqrd4v0	22	1	Arthritis	arthritis	NN
cord-017161-lcqrd4v0	22	2	or	or	CC
cord-017161-lcqrd4v0	22	3	arthralgia	arthralgia	NN
cord-017161-lcqrd4v0	22	4	4	4	CD
cord-017161-lcqrd4v0	22	5	.	.	.
cord-017161-lcqrd4v0	23	1	Renal	renal	JJ
cord-017161-lcqrd4v0	23	2	involvement	involvement	NN
cord-017161-lcqrd4v0	23	3	(	(	-LRB-
cord-017161-lcqrd4v0	23	4	proteinuria	proteinuria	NNP
cord-017161-lcqrd4v0	23	5	or	or	CC
cord-017161-lcqrd4v0	23	6	haematuria	haematuria	NN
cord-017161-lcqrd4v0	23	7	or	or	CC
cord-017161-lcqrd4v0	23	8	presence	presence	NN
cord-017161-lcqrd4v0	23	9	of	of	IN
cord-017161-lcqrd4v0	23	10	red	red	JJ
cord-017161-lcqrd4v0	23	11	blood	blood	NN
cord-017161-lcqrd4v0	23	12	cell	cell	NN
cord-017161-lcqrd4v0	23	13	casts	cast	NNS
cord-017161-lcqrd4v0	23	14	)	)	-RRB-
cord-017161-lcqrd4v0	24	1	In	in	IN
cord-017161-lcqrd4v0	24	2	cases	case	NNS
cord-017161-lcqrd4v0	24	3	with	with	IN
cord-017161-lcqrd4v0	24	4	purpura	purpura	NN
cord-017161-lcqrd4v0	24	5	with	with	IN
cord-017161-lcqrd4v0	24	6	atypical	atypical	JJ
cord-017161-lcqrd4v0	24	7	distribution	distribution	NN
cord-017161-lcqrd4v0	24	8	,	,	,
cord-017161-lcqrd4v0	24	9	a	a	DT
cord-017161-lcqrd4v0	24	10	demonstration	demonstration	NN
cord-017161-lcqrd4v0	24	11	of	of	IN
cord-017161-lcqrd4v0	24	12	IgA	IgA	NNP
cord-017161-lcqrd4v0	24	13	is	be	VBZ
cord-017161-lcqrd4v0	24	14	required	require	VBN
cord-017161-lcqrd4v0	24	15	at	at	IN
cord-017161-lcqrd4v0	24	16	biopsy	biopsy	NN
cord-017161-lcqrd4v0	24	17	.	.	.
cord-017161-lcqrd4v0	25	1	This	this	DT
cord-017161-lcqrd4v0	25	2	new	new	JJ
cord-017161-lcqrd4v0	25	3	de	de	FW
cord-017161-lcqrd4v0	25	4	fi	fi	NNP
cord-017161-lcqrd4v0	25	5	nition	nition	NN
cord-017161-lcqrd4v0	25	6	provides	provide	VBZ
cord-017161-lcqrd4v0	25	7	sensitivity	sensitivity	NN
cord-017161-lcqrd4v0	25	8	and	and	CC
cord-017161-lcqrd4v0	25	9	speci	speci	NN
cord-017161-lcqrd4v0	25	10	fi	fi	NN
cord-017161-lcqrd4v0	25	11	city	city	NN
cord-017161-lcqrd4v0	25	12	for	for	IN
cord-017161-lcqrd4v0	25	13	classi	classi	NNP
cord-017161-lcqrd4v0	25	14	fi	fi	NNP
cord-017161-lcqrd4v0	25	15	cation	cation	NNP
cord-017161-lcqrd4v0	25	16	of	of	IN
cord-017161-lcqrd4v0	25	17	HSP	HSP	NNP
cord-017161-lcqrd4v0	25	18	(	(	-LRB-
cord-017161-lcqrd4v0	25	19	using	use	VBG
cord-017161-lcqrd4v0	25	20	other	other	JJ
cord-017161-lcqrd4v0	25	21	forms	form	NNS
cord-017161-lcqrd4v0	25	22	of	of	IN
cord-017161-lcqrd4v0	25	23	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	25	24	as	as	IN
cord-017161-lcqrd4v0	25	25	controls	control	NNS
cord-017161-lcqrd4v0	25	26	)	)	-RRB-
cord-017161-lcqrd4v0	25	27	of	of	IN
cord-017161-lcqrd4v0	25	28	100	100	CD
cord-017161-lcqrd4v0	25	29	%	%	NN
cord-017161-lcqrd4v0	25	30	and	and	CC
cord-017161-lcqrd4v0	25	31	87	87	CD
cord-017161-lcqrd4v0	25	32	%	%	NN
cord-017161-lcqrd4v0	25	33	,	,	,
cord-017161-lcqrd4v0	25	34	respectively	respectively	RB
cord-017161-lcqrd4v0	25	35	[	[	-LRB-
cord-017161-lcqrd4v0	25	36	8	8	CD
cord-017161-lcqrd4v0	25	37	]	]	-RRB-
cord-017161-lcqrd4v0	25	38	.	.	.
cord-017161-lcqrd4v0	26	1	As	as	RB
cord-017161-lcqrd4v0	26	2	many	many	JJ
cord-017161-lcqrd4v0	26	3	as	as	IN
cord-017161-lcqrd4v0	26	4	50	50	CD
cord-017161-lcqrd4v0	26	5	%	%	NN
cord-017161-lcqrd4v0	26	6	of	of	IN
cord-017161-lcqrd4v0	26	7	occurrences	occurrence	NNS
cord-017161-lcqrd4v0	26	8	in	in	IN
cord-017161-lcqrd4v0	26	9	paediatric	paediatric	JJ
cord-017161-lcqrd4v0	26	10	patients	patient	NNS
cord-017161-lcqrd4v0	26	11	are	be	VBP
cord-017161-lcqrd4v0	26	12	preceded	precede	VBN
cord-017161-lcqrd4v0	26	13	by	by	IN
cord-017161-lcqrd4v0	26	14	an	an	DT
cord-017161-lcqrd4v0	26	15	upper	upper	JJ
cord-017161-lcqrd4v0	26	16	respiratory	respiratory	JJ
cord-017161-lcqrd4v0	26	17	tract	tract	NN
cord-017161-lcqrd4v0	26	18	infection	infection	NN
cord-017161-lcqrd4v0	26	19	[	[	-LRB-
cord-017161-lcqrd4v0	26	20	4	4	CD
cord-017161-lcqrd4v0	26	21	,	,	,
cord-017161-lcqrd4v0	26	22	9	9	CD
cord-017161-lcqrd4v0	26	23	]	]	-RRB-
cord-017161-lcqrd4v0	26	24	.	.	.
cord-017161-lcqrd4v0	27	1	Several	several	JJ
cord-017161-lcqrd4v0	27	2	agents	agent	NNS
cord-017161-lcqrd4v0	27	3	have	have	VBP
cord-017161-lcqrd4v0	27	4	been	be	VBN
cord-017161-lcqrd4v0	27	5	implicated	implicate	VBN
cord-017161-lcqrd4v0	27	6	,	,	,
cord-017161-lcqrd4v0	27	7	including	include	VBG
cord-017161-lcqrd4v0	27	8	group	group	NN
cord-017161-lcqrd4v0	27	9	A	a	DT
cord-017161-lcqrd4v0	27	10	streptococci	streptococcus	NNS
cord-017161-lcqrd4v0	27	11	,	,	,
cord-017161-lcqrd4v0	27	12	varicella	varicella	NN
cord-017161-lcqrd4v0	27	13	,	,	,
cord-017161-lcqrd4v0	27	14	hepatitis	hepatitis	NNP
cord-017161-lcqrd4v0	27	15	B	B	NNP
cord-017161-lcqrd4v0	27	16	,	,	,
cord-017161-lcqrd4v0	27	17	Epstein	Epstein	NNP
cord-017161-lcqrd4v0	27	18	-	-	HYPH
cord-017161-lcqrd4v0	27	19	Barr	Barr	NNP
cord-017161-lcqrd4v0	27	20	virus	virus	NN
cord-017161-lcqrd4v0	27	21	,	,	,
cord-017161-lcqrd4v0	27	22	parvovirus	parvovirus	NN
cord-017161-lcqrd4v0	27	23	B19	B19	NNP
cord-017161-lcqrd4v0	27	24	,	,	,
cord-017161-lcqrd4v0	27	25	Mycoplasma	Mycoplasma	NNP
cord-017161-lcqrd4v0	27	26	,	,	,
cord-017161-lcqrd4v0	27	27	Campylobacter	Campylobacter	NNP
cord-017161-lcqrd4v0	27	28	,	,	,
cord-017161-lcqrd4v0	27	29	and	and	CC
cord-017161-lcqrd4v0	27	30	Yersinia	Yersinia	NNP
cord-017161-lcqrd4v0	27	31	[	[	-LRB-
cord-017161-lcqrd4v0	27	32	4	4	CD
cord-017161-lcqrd4v0	27	33	]	]	-RRB-
cord-017161-lcqrd4v0	27	34	.	.	.
cord-017161-lcqrd4v0	28	1	Of	of	IN
cord-017161-lcqrd4v0	28	2	note	note	NN
cord-017161-lcqrd4v0	28	3	,	,	,
cord-017161-lcqrd4v0	28	4	Masuda	Masuda	NNP
cord-017161-lcqrd4v0	28	5	et	et	FW
cord-017161-lcqrd4v0	28	6	al	al	NNP
cord-017161-lcqrd4v0	28	7	.	.	NNP
cord-017161-lcqrd4v0	28	8	showed	show	VBD
cord-017161-lcqrd4v0	28	9	that	that	IN
cord-017161-lcqrd4v0	28	10	nephritis	nephritis	NN
cord-017161-lcqrd4v0	28	11	-	-	HYPH
cord-017161-lcqrd4v0	28	12	associated	associate	VBN
cord-017161-lcqrd4v0	28	13	plasmin	plasmin	JJ
cord-017161-lcqrd4v0	28	14	receptor	receptor	NN
cord-017161-lcqrd4v0	28	15	(	(	-LRB-
cord-017161-lcqrd4v0	28	16	NAPlr	NAPlr	NNP
cord-017161-lcqrd4v0	28	17	)	)	-RRB-
cord-017161-lcqrd4v0	28	18	,	,	,
cord-017161-lcqrd4v0	28	19	a	a	DT
cord-017161-lcqrd4v0	28	20	group	group	NN
cord-017161-lcqrd4v0	28	21	A	a	DT
cord-017161-lcqrd4v0	28	22	streptococcal	streptococcal	JJ
cord-017161-lcqrd4v0	28	23	antigen	antigen	NN
cord-017161-lcqrd4v0	28	24	,	,	,
cord-017161-lcqrd4v0	28	25	may	may	MD
cord-017161-lcqrd4v0	28	26	have	have	VB
cord-017161-lcqrd4v0	28	27	a	a	DT
cord-017161-lcqrd4v0	28	28	pathogenetic	pathogenetic	JJ
cord-017161-lcqrd4v0	28	29	role	role	NN
cord-017161-lcqrd4v0	28	30	in	in	IN
cord-017161-lcqrd4v0	28	31	a	a	DT
cord-017161-lcqrd4v0	28	32	subset	subset	NN
cord-017161-lcqrd4v0	28	33	of	of	IN
cord-017161-lcqrd4v0	28	34	patients	patient	NNS
cord-017161-lcqrd4v0	28	35	with	with	IN
cord-017161-lcqrd4v0	28	36	HSP	HSP	NNP
cord-017161-lcqrd4v0	28	37	nephritis	nephritis	NN
cord-017161-lcqrd4v0	28	38	[	[	-LRB-
cord-017161-lcqrd4v0	28	39	10	10	CD
cord-017161-lcqrd4v0	28	40	]	]	-RRB-
cord-017161-lcqrd4v0	28	41	.	.	.
cord-017161-lcqrd4v0	29	1	Among	among	IN
cord-017161-lcqrd4v0	29	2	33	33	CD
cord-017161-lcqrd4v0	29	3	children	child	NNS
cord-017161-lcqrd4v0	29	4	with	with	IN
cord-017161-lcqrd4v0	29	5	biopsy	biopsy	NN
cord-017161-lcqrd4v0	29	6	proven	prove	VBN
cord-017161-lcqrd4v0	29	7	HSP	HSP	NNP
cord-017161-lcqrd4v0	29	8	nephritis	nephritis	NN
cord-017161-lcqrd4v0	29	9	,	,	,
cord-017161-lcqrd4v0	29	10	30	30	CD
cord-017161-lcqrd4v0	29	11	%	%	NN
cord-017161-lcqrd4v0	29	12	had	have	VBD
cord-017161-lcqrd4v0	29	13	segmental	segmental	JJ
cord-017161-lcqrd4v0	29	14	or	or	CC
cord-017161-lcqrd4v0	29	15	global	global	JJ
cord-017161-lcqrd4v0	29	16	mesangial	mesangial	JJ
cord-017161-lcqrd4v0	29	17	deposition	deposition	NN
cord-017161-lcqrd4v0	29	18	of	of	IN
cord-017161-lcqrd4v0	29	19	NAPlr	NAPlr	NNP
cord-017161-lcqrd4v0	29	20	antigen	antigen	NN
cord-017161-lcqrd4v0	29	21	,	,	,
cord-017161-lcqrd4v0	29	22	comparing	compare	VBG
cord-017161-lcqrd4v0	29	23	to	to	IN
cord-017161-lcqrd4v0	29	24	3	3	CD
cord-017161-lcqrd4v0	29	25	%	%	NN
cord-017161-lcqrd4v0	29	26	in	in	IN
cord-017161-lcqrd4v0	29	27	other	other	JJ
cord-017161-lcqrd4v0	29	28	children	child	NNS
cord-017161-lcqrd4v0	29	29	with	with	IN
cord-017161-lcqrd4v0	29	30	non	non	JJ
cord-017161-lcqrd4v0	29	31	-	-	JJ
cord-017161-lcqrd4v0	29	32	HSP	hsp	JJ
cord-017161-lcqrd4v0	29	33	nephritis	nephritis	NN
cord-017161-lcqrd4v0	29	34	glomerular	glomerular	JJ
cord-017161-lcqrd4v0	29	35	diseases	disease	NNS
cord-017161-lcqrd4v0	29	36	(	(	-LRB-
cord-017161-lcqrd4v0	29	37	half	half	NN
cord-017161-lcqrd4v0	29	38	of	of	IN
cord-017161-lcqrd4v0	29	39	these	these	DT
cord-017161-lcqrd4v0	29	40	children	child	NNS
cord-017161-lcqrd4v0	29	41	had	have	VBD
cord-017161-lcqrd4v0	29	42	IgA	IgA	NNP
cord-017161-lcqrd4v0	29	43	nephropathy	nephropathy	NN
cord-017161-lcqrd4v0	29	44	)	)	-RRB-
cord-017161-lcqrd4v0	29	45	[	[	-LRB-
cord-017161-lcqrd4v0	29	46	10	10	CD
cord-017161-lcqrd4v0	29	47	]	]	-RRB-
cord-017161-lcqrd4v0	29	48	.	.	.
cord-017161-lcqrd4v0	30	1	The	the	DT
cord-017161-lcqrd4v0	30	2	exact	exact	JJ
cord-017161-lcqrd4v0	30	3	pathophysiologic	pathophysiologic	NN
cord-017161-lcqrd4v0	30	4	mechanism	mechanism	NN
cord-017161-lcqrd4v0	30	5	,	,	,
cord-017161-lcqrd4v0	30	6	if	if	IN
cord-017161-lcqrd4v0	30	7	any	any	DT
cord-017161-lcqrd4v0	30	8	,	,	,
cord-017161-lcqrd4v0	30	9	and	and	CC
cord-017161-lcqrd4v0	30	10	the	the	DT
cord-017161-lcqrd4v0	30	11	relationship	relationship	NN
cord-017161-lcqrd4v0	30	12	between	between	IN
cord-017161-lcqrd4v0	30	13	NAPlr	NAPlr	NNP
cord-017161-lcqrd4v0	30	14	and	and	CC
cord-017161-lcqrd4v0	30	15	HSP	HSP	NNP
cord-017161-lcqrd4v0	30	16	nephritis	nephritis	NN
cord-017161-lcqrd4v0	30	17	need	need	VBP
cord-017161-lcqrd4v0	30	18	,	,	,
cord-017161-lcqrd4v0	30	19	however	however	RB
cord-017161-lcqrd4v0	30	20	,	,	,
cord-017161-lcqrd4v0	30	21	further	further	JJ
cord-017161-lcqrd4v0	30	22	investigation	investigation	NN
cord-017161-lcqrd4v0	30	23	.	.	.
cord-017161-lcqrd4v0	31	1	So	so	RB
cord-017161-lcqrd4v0	31	2	far	far	RB
cord-017161-lcqrd4v0	31	3	no	no	DT
cord-017161-lcqrd4v0	31	4	single	single	JJ
cord-017161-lcqrd4v0	31	5	infectious	infectious	JJ
cord-017161-lcqrd4v0	31	6	agent	agent	NN
cord-017161-lcqrd4v0	31	7	has	have	VBZ
cord-017161-lcqrd4v0	31	8	been	be	VBN
cord-017161-lcqrd4v0	31	9	consistently	consistently	RB
cord-017161-lcqrd4v0	31	10	identi	identi	FW
cord-017161-lcqrd4v0	31	11	fi	fi	FW
cord-017161-lcqrd4v0	31	12	ed	ed	NN
cord-017161-lcqrd4v0	31	13	,	,	,
cord-017161-lcqrd4v0	31	14	and	and	CC
cord-017161-lcqrd4v0	31	15	it	-PRON-	PRP
cord-017161-lcqrd4v0	31	16	is	be	VBZ
cord-017161-lcqrd4v0	31	17	likely	likely	JJ
cord-017161-lcqrd4v0	31	18	that	that	IN
cord-017161-lcqrd4v0	31	19	genetically	genetically	RB
cord-017161-lcqrd4v0	31	20	controlled	control	VBN
cord-017161-lcqrd4v0	31	21	host	host	NN
cord-017161-lcqrd4v0	31	22	responses	response	NNS
cord-017161-lcqrd4v0	31	23	determine	determine	VBP
cord-017161-lcqrd4v0	31	24	whether	whether	IN
cord-017161-lcqrd4v0	31	25	or	or	CC
cord-017161-lcqrd4v0	31	26	not	not	RB
cord-017161-lcqrd4v0	31	27	an	an	DT
cord-017161-lcqrd4v0	31	28	individual	individual	NN
cord-017161-lcqrd4v0	31	29	develops	develop	VBZ
cord-017161-lcqrd4v0	31	30	HSP	HSP	NNP
cord-017161-lcqrd4v0	31	31	in	in	IN
cord-017161-lcqrd4v0	31	32	response	response	NN
cord-017161-lcqrd4v0	31	33	to	to	IN
cord-017161-lcqrd4v0	31	34	infectious	infectious	JJ
cord-017161-lcqrd4v0	31	35	triggers	trigger	NNS
cord-017161-lcqrd4v0	31	36	.	.	.
cord-017161-lcqrd4v0	32	1	But	but	CC
cord-017161-lcqrd4v0	32	2	despite	despite	IN
cord-017161-lcqrd4v0	32	3	the	the	DT
cord-017161-lcqrd4v0	32	4	fact	fact	NN
cord-017161-lcqrd4v0	32	5	that	that	IN
cord-017161-lcqrd4v0	32	6	the	the	DT
cord-017161-lcqrd4v0	32	7	cause	cause	NN
cord-017161-lcqrd4v0	32	8	of	of	IN
cord-017161-lcqrd4v0	32	9	HSP	HSP	NNP
cord-017161-lcqrd4v0	32	10	is	be	VBZ
cord-017161-lcqrd4v0	32	11	unknown	unknown	JJ
cord-017161-lcqrd4v0	32	12	,	,	,
cord-017161-lcqrd4v0	32	13	it	-PRON-	PRP
cord-017161-lcqrd4v0	32	14	is	be	VBZ
cord-017161-lcqrd4v0	32	15	likely	likely	JJ
cord-017161-lcqrd4v0	32	16	that	that	IN
cord-017161-lcqrd4v0	32	17	IgA	IgA	NNP
cord-017161-lcqrd4v0	32	18	has	have	VBZ
cord-017161-lcqrd4v0	32	19	a	a	DT
cord-017161-lcqrd4v0	32	20	pivotal	pivotal	JJ
cord-017161-lcqrd4v0	32	21	role	role	NN
cord-017161-lcqrd4v0	32	22	in	in	IN
cord-017161-lcqrd4v0	32	23	the	the	DT
cord-017161-lcqrd4v0	32	24	pathogenesis	pathogenesis	NN
cord-017161-lcqrd4v0	32	25	of	of	IN
cord-017161-lcqrd4v0	32	26	the	the	DT
cord-017161-lcqrd4v0	32	27	disease	disease	NN
cord-017161-lcqrd4v0	32	28	,	,	,
cord-017161-lcqrd4v0	32	29	a	a	DT
cord-017161-lcqrd4v0	32	30	hypothesis	hypothesis	NN
cord-017161-lcqrd4v0	32	31	supported	support	VBN
cord-017161-lcqrd4v0	32	32	by	by	IN
cord-017161-lcqrd4v0	32	33	the	the	DT
cord-017161-lcqrd4v0	32	34	almost	almost	RB
cord-017161-lcqrd4v0	32	35	universal	universal	JJ
cord-017161-lcqrd4v0	32	36	deposition	deposition	NN
cord-017161-lcqrd4v0	32	37	of	of	IN
cord-017161-lcqrd4v0	32	38	IgA	IgA	NNP
cord-017161-lcqrd4v0	32	39	in	in	IN
cord-017161-lcqrd4v0	32	40	lesional	lesional	JJ
cord-017161-lcqrd4v0	32	41	vascular	vascular	JJ
cord-017161-lcqrd4v0	32	42	tissue	tissue	NN
cord-017161-lcqrd4v0	32	43	[	[	-LRB-
cord-017161-lcqrd4v0	32	44	11	11	CD
cord-017161-lcqrd4v0	32	45	]	]	-RRB-
cord-017161-lcqrd4v0	32	46	.	.	.
cord-017161-lcqrd4v0	33	1	Skin	skin	NN
cord-017161-lcqrd4v0	33	2	or	or	CC
cord-017161-lcqrd4v0	33	3	renal	renal	JJ
cord-017161-lcqrd4v0	33	4	biopsies	biopsy	NNS
cord-017161-lcqrd4v0	33	5	demonstrate	demonstrate	VBP
cord-017161-lcqrd4v0	33	6	the	the	DT
cord-017161-lcqrd4v0	33	7	deposition	deposition	NN
cord-017161-lcqrd4v0	33	8	of	of	IN
cord-017161-lcqrd4v0	33	9	IgA	IgA	NNP
cord-017161-lcqrd4v0	33	10	(	(	-LRB-
cord-017161-lcqrd4v0	33	11	mainly	mainly	RB
cord-017161-lcqrd4v0	33	12	IgA1	IgA1	NNP
cord-017161-lcqrd4v0	33	13	)	)	-RRB-
cord-017161-lcqrd4v0	33	14	in	in	IN
cord-017161-lcqrd4v0	33	15	the	the	DT
cord-017161-lcqrd4v0	33	16	wall	wall	NN
cord-017161-lcqrd4v0	33	17	of	of	IN
cord-017161-lcqrd4v0	33	18	dermal	dermal	JJ
cord-017161-lcqrd4v0	33	19	capillaries	capillary	NNS
cord-017161-lcqrd4v0	33	20	and	and	CC
cord-017161-lcqrd4v0	33	21	post	post	JJ
cord-017161-lcqrd4v0	33	22	-	-	JJ
cord-017161-lcqrd4v0	33	23	capillary	capillary	JJ
cord-017161-lcqrd4v0	33	24	venules	venule	NNS
cord-017161-lcqrd4v0	33	25	and	and	CC
cord-017161-lcqrd4v0	33	26	mesangium	mesangium	NNP
cord-017161-lcqrd4v0	33	27	[	[	-LRB-
cord-017161-lcqrd4v0	33	28	11	11	CD
cord-017161-lcqrd4v0	33	29	]	]	-RRB-
cord-017161-lcqrd4v0	33	30	.	.	.
cord-017161-lcqrd4v0	34	1	In	in	IN
cord-017161-lcqrd4v0	34	2	addition	addition	NN
cord-017161-lcqrd4v0	34	3	,	,	,
cord-017161-lcqrd4v0	34	4	serum	serum	NN
cord-017161-lcqrd4v0	34	5	IgA	IgA	NNP
cord-017161-lcqrd4v0	34	6	levels	level	NNS
cord-017161-lcqrd4v0	34	7	have	have	VBP
cord-017161-lcqrd4v0	34	8	been	be	VBN
cord-017161-lcqrd4v0	34	9	reported	report	VBN
cord-017161-lcqrd4v0	34	10	to	to	TO
cord-017161-lcqrd4v0	34	11	be	be	VB
cord-017161-lcqrd4v0	34	12	increased	increase	VBN
cord-017161-lcqrd4v0	34	13	during	during	IN
cord-017161-lcqrd4v0	34	14	the	the	DT
cord-017161-lcqrd4v0	34	15	acute	acute	JJ
cord-017161-lcqrd4v0	34	16	phase	phase	NN
cord-017161-lcqrd4v0	34	17	of	of	IN
cord-017161-lcqrd4v0	34	18	the	the	DT
cord-017161-lcqrd4v0	34	19	disease	disease	NN
cord-017161-lcqrd4v0	34	20	,	,	,
cord-017161-lcqrd4v0	34	21	and	and	CC
cord-017161-lcqrd4v0	34	22	a	a	DT
cord-017161-lcqrd4v0	34	23	proportion	proportion	NN
cord-017161-lcqrd4v0	34	24	of	of	IN
cord-017161-lcqrd4v0	34	25	patients	patient	NNS
cord-017161-lcqrd4v0	34	26	have	have	VBP
cord-017161-lcqrd4v0	34	27	circulating	circulate	VBG
cord-017161-lcqrd4v0	34	28	IgA	IgA	NNP
cord-017161-lcqrd4v0	34	29	-	-	HYPH
cord-017161-lcqrd4v0	34	30	containing	contain	VBG
cord-017161-lcqrd4v0	34	31	immune	immune	JJ
cord-017161-lcqrd4v0	34	32	complexes	complex	NNS
cord-017161-lcqrd4v0	34	33	and	and	CC
cord-017161-lcqrd4v0	34	34	cryoglobulins	cryoglobulin	NNS
cord-017161-lcqrd4v0	34	35	[	[	-LRB-
cord-017161-lcqrd4v0	34	36	12	12	CD
cord-017161-lcqrd4v0	34	37	]	]	-RRB-
cord-017161-lcqrd4v0	34	38	.	.	.
cord-017161-lcqrd4v0	35	1	Some	some	DT
cord-017161-lcqrd4v0	35	2	studies	study	NNS
cord-017161-lcqrd4v0	35	3	have	have	VBP
cord-017161-lcqrd4v0	35	4	found	find	VBN
cord-017161-lcqrd4v0	35	5	IgA	IgA	NNP
cord-017161-lcqrd4v0	35	6	antineutrophil	antineutrophil	NNP
cord-017161-lcqrd4v0	35	7	cytoplasmic	cytoplasmic	JJ
cord-017161-lcqrd4v0	35	8	antibodies	antibody	NNS
cord-017161-lcqrd4v0	35	9	(	(	-LRB-
cord-017161-lcqrd4v0	35	10	IgA	IgA	NNP
cord-017161-lcqrd4v0	35	11	-	-	HYPH
cord-017161-lcqrd4v0	35	12	ANCAs	ANCAs	NNP
cord-017161-lcqrd4v0	35	13	)	)	-RRB-
cord-017161-lcqrd4v0	35	14	in	in	IN
cord-017161-lcqrd4v0	35	15	a	a	DT
cord-017161-lcqrd4v0	35	16	proportion	proportion	NN
cord-017161-lcqrd4v0	35	17	of	of	IN
cord-017161-lcqrd4v0	35	18	patients	patient	NNS
cord-017161-lcqrd4v0	35	19	with	with	IN
cord-017161-lcqrd4v0	35	20	HSP	HSP	NNP
cord-017161-lcqrd4v0	35	21	,	,	,
cord-017161-lcqrd4v0	35	22	while	while	IN
cord-017161-lcqrd4v0	35	23	others	other	NNS
cord-017161-lcqrd4v0	35	24	have	have	VBP
cord-017161-lcqrd4v0	35	25	shown	show	VBN
cord-017161-lcqrd4v0	35	26	an	an	DT
cord-017161-lcqrd4v0	35	27	increase	increase	NN
cord-017161-lcqrd4v0	35	28	in	in	IN
cord-017161-lcqrd4v0	35	29	IgA	IgA	NNP
cord-017161-lcqrd4v0	35	30	-	-	HYPH
cord-017161-lcqrd4v0	35	31	rheumatoid	rheumatoid	NNP
cord-017161-lcqrd4v0	35	32	factor	factor	NN
cord-017161-lcqrd4v0	35	33	or	or	CC
cord-017161-lcqrd4v0	35	34	IgA	IgA	NNP
cord-017161-lcqrd4v0	35	35	-	-	HYPH
cord-017161-lcqrd4v0	35	36	anticardiolipin	anticardiolipin	NNP
cord-017161-lcqrd4v0	35	37	antibodies	antibody	NNS
cord-017161-lcqrd4v0	35	38	[	[	-LRB-
cord-017161-lcqrd4v0	35	39	11	11	CD
cord-017161-lcqrd4v0	35	40	]	]	-RRB-
cord-017161-lcqrd4v0	35	41	.	.	.
cord-017161-lcqrd4v0	36	1	Recently	recently	RB
cord-017161-lcqrd4v0	36	2	,	,	,
cord-017161-lcqrd4v0	36	3	galactose	galactose	NN
cord-017161-lcqrd4v0	36	4	de	de	NNP
cord-017161-lcqrd4v0	36	5	fi	fi	FW
cord-017161-lcqrd4v0	36	6	ciency	ciency	NN
cord-017161-lcqrd4v0	36	7	of	of	IN
cord-017161-lcqrd4v0	36	8	O	o	NN
cord-017161-lcqrd4v0	36	9	-	-	HYPH
cord-017161-lcqrd4v0	36	10	linked	link	VBN
cord-017161-lcqrd4v0	36	11	glycans	glycan	NNS
cord-017161-lcqrd4v0	36	12	in	in	IN
cord-017161-lcqrd4v0	36	13	the	the	DT
cord-017161-lcqrd4v0	36	14	hinge	hinge	NN
cord-017161-lcqrd4v0	36	15	region	region	NN
cord-017161-lcqrd4v0	36	16	of	of	IN
cord-017161-lcqrd4v0	36	17	IgA1	iga1	PRP
cord-017161-lcqrd4v0	36	18	has	have	VBZ
cord-017161-lcqrd4v0	36	19	been	be	VBN
cord-017161-lcqrd4v0	36	20	reported	report	VBN
cord-017161-lcqrd4v0	36	21	in	in	IN
cord-017161-lcqrd4v0	36	22	adults	adult	NNS
cord-017161-lcqrd4v0	36	23	with	with	IN
cord-017161-lcqrd4v0	36	24	IgA	IgA	NNP
cord-017161-lcqrd4v0	36	25	nephropathy	nephropathy	NNP
cord-017161-lcqrd4v0	36	26	and	and	CC
cord-017161-lcqrd4v0	36	27	children	child	NNS
cord-017161-lcqrd4v0	36	28	with	with	IN
cord-017161-lcqrd4v0	36	29	HSP	HSP	NNP
cord-017161-lcqrd4v0	36	30	[	[	-LRB-
cord-017161-lcqrd4v0	36	31	13	13	CD
cord-017161-lcqrd4v0	36	32	]	]	-RRB-
cord-017161-lcqrd4v0	36	33	.	.	.
cord-017161-lcqrd4v0	37	1	These	these	DT
cord-017161-lcqrd4v0	37	2	aberrantly	aberrantly	RB
cord-017161-lcqrd4v0	37	3	glycosylated	glycosylate	VBN
cord-017161-lcqrd4v0	37	4	IgA1	iga1	PRP
cord-017161-lcqrd4v0	37	5	proteins	protein	NNS
cord-017161-lcqrd4v0	37	6	form	form	VBP
cord-017161-lcqrd4v0	37	7	immune	immune	JJ
cord-017161-lcqrd4v0	37	8	complexes	complex	NNS
cord-017161-lcqrd4v0	37	9	that	that	WDT
cord-017161-lcqrd4v0	37	10	deposit	deposit	VBP
cord-017161-lcqrd4v0	37	11	in	in	IN
cord-017161-lcqrd4v0	37	12	the	the	DT
cord-017161-lcqrd4v0	37	13	mesangium	mesangium	NN
cord-017161-lcqrd4v0	37	14	;	;	:
cord-017161-lcqrd4v0	37	15	their	-PRON-	PRP$
cord-017161-lcqrd4v0	37	16	binding	binding	NN
cord-017161-lcqrd4v0	37	17	to	to	IN
cord-017161-lcqrd4v0	37	18	mesangial	mesangial	JJ
cord-017161-lcqrd4v0	37	19	cells	cell	NNS
cord-017161-lcqrd4v0	37	20	stimulates	stimulate	VBZ
cord-017161-lcqrd4v0	37	21	cellular	cellular	JJ
cord-017161-lcqrd4v0	37	22	proliferation	proliferation	NN
cord-017161-lcqrd4v0	37	23	and	and	CC
cord-017161-lcqrd4v0	37	24	overexpression	overexpression	NN
cord-017161-lcqrd4v0	37	25	of	of	IN
cord-017161-lcqrd4v0	37	26	extracellular	extracellular	JJ
cord-017161-lcqrd4v0	37	27	matrix	matrix	NN
cord-017161-lcqrd4v0	37	28	components	component	NNS
cord-017161-lcqrd4v0	37	29	resulting	result	VBG
cord-017161-lcqrd4v0	37	30	in	in	IN
cord-017161-lcqrd4v0	37	31	the	the	DT
cord-017161-lcqrd4v0	37	32	typical	typical	JJ
cord-017161-lcqrd4v0	37	33	renal	renal	JJ
cord-017161-lcqrd4v0	37	34	lesions	lesion	NNS
cord-017161-lcqrd4v0	37	35	associated	associate	VBN
cord-017161-lcqrd4v0	37	36	with	with	IN
cord-017161-lcqrd4v0	37	37	HSP	HSP	NNP
cord-017161-lcqrd4v0	37	38	[	[	-LRB-
cord-017161-lcqrd4v0	37	39	13	13	CD
cord-017161-lcqrd4v0	37	40	]	]	-RRB-
cord-017161-lcqrd4v0	37	41	.	.	.
cord-017161-lcqrd4v0	38	1	Recently	recently	RB
cord-017161-lcqrd4v0	38	2	,	,	,
cord-017161-lcqrd4v0	38	3	Hiasano	Hiasano	NNP
cord-017161-lcqrd4v0	38	4	et	et	NNP
cord-017161-lcqrd4v0	38	5	al	al	NNP
cord-017161-lcqrd4v0	38	6	.	.	.
cord-017161-lcqrd4v0	39	1	showed	show	VBD
cord-017161-lcqrd4v0	39	2	complement	complement	JJ
cord-017161-lcqrd4v0	39	3	activation	activation	NN
cord-017161-lcqrd4v0	39	4	through	through	IN
cord-017161-lcqrd4v0	39	5	both	both	CC
cord-017161-lcqrd4v0	39	6	the	the	DT
cord-017161-lcqrd4v0	39	7	alternative	alternative	NN
cord-017161-lcqrd4v0	39	8	and	and	CC
cord-017161-lcqrd4v0	39	9	lectin	lectin	NN
cord-017161-lcqrd4v0	39	10	pathways	pathway	NNS
cord-017161-lcqrd4v0	39	11	in	in	IN
cord-017161-lcqrd4v0	39	12	patients	patient	NNS
cord-017161-lcqrd4v0	39	13	with	with	IN
cord-017161-lcqrd4v0	39	14	HSP	HSP	NNP
cord-017161-lcqrd4v0	39	15	nephritis	nephritis	NN
cord-017161-lcqrd4v0	39	16	and	and	CC
cord-017161-lcqrd4v0	39	17	demonstrated	demonstrate	VBD
cord-017161-lcqrd4v0	39	18	that	that	IN
cord-017161-lcqrd4v0	39	19	this	this	DT
cord-017161-lcqrd4v0	39	20	complement	complement	NN
cord-017161-lcqrd4v0	39	21	activation	activation	NN
cord-017161-lcqrd4v0	39	22	is	be	VBZ
cord-017161-lcqrd4v0	39	23	promoted	promote	VBN
cord-017161-lcqrd4v0	39	24	in	in	IN
cord-017161-lcqrd4v0	39	25	situ	situ	NN
cord-017161-lcqrd4v0	39	26	in	in	IN
cord-017161-lcqrd4v0	39	27	the	the	DT
cord-017161-lcqrd4v0	39	28	glomerulus	glomerulus	NN
cord-017161-lcqrd4v0	39	29	[	[	-LRB-
cord-017161-lcqrd4v0	39	30	14	14	CD
cord-017161-lcqrd4v0	39	31	]	]	-RRB-
cord-017161-lcqrd4v0	39	32	.	.	.
cord-017161-lcqrd4v0	40	1	The	the	DT
cord-017161-lcqrd4v0	40	2	formed	form	VBN
cord-017161-lcqrd4v0	40	3	IgA	IgA	NNP
cord-017161-lcqrd4v0	40	4	immune	immune	JJ
cord-017161-lcqrd4v0	40	5	complexes	complex	NNS
cord-017161-lcqrd4v0	40	6	,	,	,
cord-017161-lcqrd4v0	40	7	through	through	IN
cord-017161-lcqrd4v0	40	8	the	the	DT
cord-017161-lcqrd4v0	40	9	activation	activation	NN
cord-017161-lcqrd4v0	40	10	of	of	IN
cord-017161-lcqrd4v0	40	11	complement	complement	NN
cord-017161-lcqrd4v0	40	12	,	,	,
cord-017161-lcqrd4v0	40	13	lead	lead	VB
cord-017161-lcqrd4v0	40	14	to	to	IN
cord-017161-lcqrd4v0	40	15	the	the	DT
cord-017161-lcqrd4v0	40	16	formation	formation	NN
cord-017161-lcqrd4v0	40	17	of	of	IN
cord-017161-lcqrd4v0	40	18	chemotactic	chemotactic	JJ
cord-017161-lcqrd4v0	40	19	factors	factor	NNS
cord-017161-lcqrd4v0	40	20	(	(	-LRB-
cord-017161-lcqrd4v0	40	21	such	such	JJ
cord-017161-lcqrd4v0	40	22	as	as	IN
cord-017161-lcqrd4v0	40	23	C5a	C5a	NNS
cord-017161-lcqrd4v0	40	24	)	)	-RRB-
cord-017161-lcqrd4v0	40	25	,	,	,
cord-017161-lcqrd4v0	40	26	which	which	WDT
cord-017161-lcqrd4v0	40	27	in	in	IN
cord-017161-lcqrd4v0	40	28	turn	turn	NN
cord-017161-lcqrd4v0	40	29	recruit	recruit	VBP
cord-017161-lcqrd4v0	40	30	polymorphonuclear	polymorphonuclear	NNP
cord-017161-lcqrd4v0	40	31	leucocytes	leucocyte	NNS
cord-017161-lcqrd4v0	40	32	to	to	IN
cord-017161-lcqrd4v0	40	33	the	the	DT
cord-017161-lcqrd4v0	40	34	site	site	NN
cord-017161-lcqrd4v0	40	35	of	of	IN
cord-017161-lcqrd4v0	40	36	deposition	deposition	NN
cord-017161-lcqrd4v0	40	37	[	[	-LRB-
cord-017161-lcqrd4v0	40	38	15	15	CD
cord-017161-lcqrd4v0	40	39	,	,	,
cord-017161-lcqrd4v0	40	40	16	16	CD
cord-017161-lcqrd4v0	40	41	]	]	-RRB-
cord-017161-lcqrd4v0	40	42	.	.	.
cord-017161-lcqrd4v0	41	1	The	the	DT
cord-017161-lcqrd4v0	41	2	polymorphonuclear	polymorphonuclear	JJ
cord-017161-lcqrd4v0	41	3	leucocytes	leucocytes	NNP
cord-017161-lcqrd4v0	41	4	thus	thus	RB
cord-017161-lcqrd4v0	41	5	recruited	recruit	VBN
cord-017161-lcqrd4v0	41	6	by	by	IN
cord-017161-lcqrd4v0	41	7	chemotactic	chemotactic	JJ
cord-017161-lcqrd4v0	41	8	factors	factor	NNS
cord-017161-lcqrd4v0	41	9	cause	cause	VBP
cord-017161-lcqrd4v0	41	10	in	in	IN
cord-017161-lcqrd4v0	41	11	fl	fl	NNP
cord-017161-lcqrd4v0	41	12	ammation	ammation	NN
cord-017161-lcqrd4v0	41	13	and	and	CC
cord-017161-lcqrd4v0	41	14	necrosis	necrosis	NN
cord-017161-lcqrd4v0	41	15	of	of	IN
cord-017161-lcqrd4v0	41	16	vessel	vessel	NN
cord-017161-lcqrd4v0	41	17	walls	wall	NNS
cord-017161-lcqrd4v0	41	18	with	with	IN
cord-017161-lcqrd4v0	41	19	concomitant	concomitant	JJ
cord-017161-lcqrd4v0	41	20	thrombosis	thrombosis	NN
cord-017161-lcqrd4v0	41	21	[	[	-LRB-
cord-017161-lcqrd4v0	41	22	11	11	CD
cord-017161-lcqrd4v0	41	23	]	]	-RRB-
cord-017161-lcqrd4v0	41	24	.	.	.
cord-017161-lcqrd4v0	42	1	This	this	DT
cord-017161-lcqrd4v0	42	2	subsequently	subsequently	RB
cord-017161-lcqrd4v0	42	3	results	result	VBZ
cord-017161-lcqrd4v0	42	4	in	in	IN
cord-017161-lcqrd4v0	42	5	extravasation	extravasation	NN
cord-017161-lcqrd4v0	42	6	of	of	IN
cord-017161-lcqrd4v0	42	7	erythrocytes	erythrocyte	NNS
cord-017161-lcqrd4v0	42	8	from	from	IN
cord-017161-lcqrd4v0	42	9	haemorrhage	haemorrhage	NN
cord-017161-lcqrd4v0	42	10	in	in	IN
cord-017161-lcqrd4v0	42	11	the	the	DT
cord-017161-lcqrd4v0	42	12	affected	affected	JJ
cord-017161-lcqrd4v0	42	13	organs	organ	NNS
cord-017161-lcqrd4v0	42	14	and	and	CC
cord-017161-lcqrd4v0	42	15	is	be	VBZ
cord-017161-lcqrd4v0	42	16	manifested	manifest	VBN
cord-017161-lcqrd4v0	42	17	histologically	histologically	RB
cord-017161-lcqrd4v0	42	18	as	as	IN
cord-017161-lcqrd4v0	42	19	leucocytoclastic	leucocytoclastic	JJ
cord-017161-lcqrd4v0	42	20	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	42	21	[	[	-LRB-
cord-017161-lcqrd4v0	42	22	11	11	CD
cord-017161-lcqrd4v0	42	23	]	]	-RRB-
cord-017161-lcqrd4v0	42	24	.	.	.
cord-017161-lcqrd4v0	43	1	The	the	DT
cord-017161-lcqrd4v0	43	2	term	term	NN
cord-017161-lcqrd4v0	43	3	leucocytoclasis	leucocytoclasis	NN
cord-017161-lcqrd4v0	43	4	refers	refer	VBZ
cord-017161-lcqrd4v0	43	5	to	to	IN
cord-017161-lcqrd4v0	43	6	the	the	DT
cord-017161-lcqrd4v0	43	7	breakdown	breakdown	NN
cord-017161-lcqrd4v0	43	8	of	of	IN
cord-017161-lcqrd4v0	43	9	white	white	JJ
cord-017161-lcqrd4v0	43	10	blood	blood	NN
cord-017161-lcqrd4v0	43	11	cells	cell	NNS
cord-017161-lcqrd4v0	43	12	in	in	IN
cord-017161-lcqrd4v0	43	13	lesional	lesional	JJ
cord-017161-lcqrd4v0	43	14	tissue	tissue	NN
cord-017161-lcqrd4v0	43	15	,	,	,
cord-017161-lcqrd4v0	43	16	particularly	particularly	RB
cord-017161-lcqrd4v0	43	17	the	the	DT
cord-017161-lcqrd4v0	43	18	characteristic	characteristic	JJ
cord-017161-lcqrd4v0	43	19	nuclear	nuclear	JJ
cord-017161-lcqrd4v0	43	20	debris	debris	NN
cord-017161-lcqrd4v0	43	21	(	(	-LRB-
cord-017161-lcqrd4v0	43	22	"	"	``
cord-017161-lcqrd4v0	43	23	nuclear	nuclear	JJ
cord-017161-lcqrd4v0	43	24	dust	dust	NN
cord-017161-lcqrd4v0	43	25	"	"	''
cord-017161-lcqrd4v0	43	26	)	)	-RRB-
cord-017161-lcqrd4v0	43	27	observed	observe	VBD
cord-017161-lcqrd4v0	43	28	,	,	,
cord-017161-lcqrd4v0	43	29	and	and	CC
cord-017161-lcqrd4v0	43	30	is	be	VBZ
cord-017161-lcqrd4v0	43	31	not	not	RB
cord-017161-lcqrd4v0	43	32	speci	speci	FW
cord-017161-lcqrd4v0	43	33	fi	fi	NN
cord-017161-lcqrd4v0	43	34	c	c	NN
cord-017161-lcqrd4v0	43	35	for	for	IN
cord-017161-lcqrd4v0	43	36	HSP	HSP	NNP
cord-017161-lcqrd4v0	43	37	.	.	.
cord-017161-lcqrd4v0	44	1	Several	several	JJ
cord-017161-lcqrd4v0	44	2	genetic	genetic	JJ
cord-017161-lcqrd4v0	44	3	polymorphisms	polymorphism	NNS
cord-017161-lcqrd4v0	44	4	have	have	VBP
cord-017161-lcqrd4v0	44	5	been	be	VBN
cord-017161-lcqrd4v0	44	6	linked	link	VBN
cord-017161-lcqrd4v0	44	7	with	with	IN
cord-017161-lcqrd4v0	44	8	HSP	HSP	NNP
cord-017161-lcqrd4v0	44	9	in	in	IN
cord-017161-lcqrd4v0	44	10	various	various	JJ
cord-017161-lcqrd4v0	44	11	population	population	NN
cord-017161-lcqrd4v0	44	12	cohorts	cohort	NNS
cord-017161-lcqrd4v0	44	13	,	,	,
cord-017161-lcqrd4v0	44	14	often	often	RB
cord-017161-lcqrd4v0	44	15	with	with	IN
cord-017161-lcqrd4v0	44	16	consistent	consistent	JJ
cord-017161-lcqrd4v0	44	17	results	result	NNS
cord-017161-lcqrd4v0	44	18	across	across	IN
cord-017161-lcqrd4v0	44	19	multiple	multiple	JJ
cord-017161-lcqrd4v0	44	20	studies	study	NNS
cord-017161-lcqrd4v0	44	21	(	(	-LRB-
cord-017161-lcqrd4v0	44	22	summarized	summarize	VBN
cord-017161-lcqrd4v0	44	23	in	in	IN
cord-017161-lcqrd4v0	44	24	Table	Table	NNP
cord-017161-lcqrd4v0	44	25	2	2	CD
cord-017161-lcqrd4v0	44	26	.1	.1	CD
cord-017161-lcqrd4v0	44	27	)	)	-RRB-
cord-017161-lcqrd4v0	45	1	[	[	-LRB-
cord-017161-lcqrd4v0	45	2	32	32	CD
cord-017161-lcqrd4v0	45	3	]	]	-RRB-
cord-017161-lcqrd4v0	45	4	.	.	.
cord-017161-lcqrd4v0	46	1	Many	many	JJ
cord-017161-lcqrd4v0	46	2	of	of	IN
cord-017161-lcqrd4v0	46	3	these	these	DT
cord-017161-lcqrd4v0	46	4	polymorphisms	polymorphism	NNS
cord-017161-lcqrd4v0	46	5	relate	relate	VBP
cord-017161-lcqrd4v0	46	6	to	to	IN
cord-017161-lcqrd4v0	46	7	cytokines	cytokine	NNS
cord-017161-lcqrd4v0	46	8	or	or	CC
cord-017161-lcqrd4v0	46	9	cell	cell	NN
cord-017161-lcqrd4v0	46	10	adhesion	adhesion	NN
cord-017161-lcqrd4v0	46	11	molecules	molecule	NNS
cord-017161-lcqrd4v0	46	12	involved	involve	VBN
cord-017161-lcqrd4v0	46	13	in	in	IN
cord-017161-lcqrd4v0	46	14	the	the	DT
cord-017161-lcqrd4v0	46	15	modulation	modulation	NN
cord-017161-lcqrd4v0	46	16	of	of	IN
cord-017161-lcqrd4v0	46	17	in	in	IN
cord-017161-lcqrd4v0	46	18	fl	fl	NNP
cord-017161-lcqrd4v0	46	19	ammatory	ammatory	NNP
cord-017161-lcqrd4v0	46	20	responses	response	NNS
cord-017161-lcqrd4v0	46	21	and	and	CC
cord-017161-lcqrd4v0	46	22	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	46	23	cell	cell	NN
cord-017161-lcqrd4v0	46	24	activation	activation	NN
cord-017161-lcqrd4v0	46	25	[	[	-LRB-
cord-017161-lcqrd4v0	46	26	4	4	CD
cord-017161-lcqrd4v0	46	27	,	,	,
cord-017161-lcqrd4v0	46	28	32	32	CD
cord-017161-lcqrd4v0	46	29	]	]	-RRB-
cord-017161-lcqrd4v0	46	30	.	.	.
cord-017161-lcqrd4v0	47	1	The	the	DT
cord-017161-lcqrd4v0	47	2	connection	connection	NN
cord-017161-lcqrd4v0	47	3	between	between	IN
cord-017161-lcqrd4v0	47	4	HSP	HSP	NNP
cord-017161-lcqrd4v0	47	5	and	and	CC
cord-017161-lcqrd4v0	47	6	HLA	HLA	NNP
cord-017161-lcqrd4v0	47	7	alleles	allele	NNS
cord-017161-lcqrd4v0	47	8	is	be	VBZ
cord-017161-lcqrd4v0	47	9	the	the	DT
cord-017161-lcqrd4v0	47	10	most	most	RBS
cord-017161-lcqrd4v0	47	11	convincing	convincing	JJ
cord-017161-lcqrd4v0	47	12	genetic	genetic	JJ
cord-017161-lcqrd4v0	47	13	association	association	NN
cord-017161-lcqrd4v0	47	14	.	.	.
cord-017161-lcqrd4v0	48	1	In	in	IN
cord-017161-lcqrd4v0	48	2	three	three	CD
cord-017161-lcqrd4v0	48	3	cohorts	cohort	NNS
cord-017161-lcqrd4v0	48	4	from	from	IN
cord-017161-lcqrd4v0	48	5	Italy	Italy	NNP
cord-017161-lcqrd4v0	48	6	,	,	,
cord-017161-lcqrd4v0	48	7	northwest	northwest	NN
cord-017161-lcqrd4v0	48	8	Spain	Spain	NNP
cord-017161-lcqrd4v0	48	9	and	and	CC
cord-017161-lcqrd4v0	48	10	Turkey	Turkey	NNP
cord-017161-lcqrd4v0	48	11	,	,	,
cord-017161-lcqrd4v0	48	12	DRB1	DRB1	NNP
cord-017161-lcqrd4v0	49	1	*	*	NFP
cord-017161-lcqrd4v0	49	2	01	01	CD
cord-017161-lcqrd4v0	49	3	and	and	CC
cord-017161-lcqrd4v0	49	4	DRB*11	drb*11	NN
cord-017161-lcqrd4v0	49	5	have	have	VBP
cord-017161-lcqrd4v0	49	6	each	each	DT
cord-017161-lcqrd4v0	49	7	been	be	VBN
cord-017161-lcqrd4v0	49	8	positively	positively	RB
cord-017161-lcqrd4v0	49	9	associated	associate	VBN
cord-017161-lcqrd4v0	49	10	(	(	-LRB-
cord-017161-lcqrd4v0	49	11	OR	or	CC
cord-017161-lcqrd4v0	49	12	1.5	1.5	CD
cord-017161-lcqrd4v0	49	13	-	-	SYM
cord-017161-lcqrd4v0	49	14	2.5	2.5	CD
cord-017161-lcqrd4v0	49	15	)	)	-RRB-
cord-017161-lcqrd4v0	49	16	,	,	,
cord-017161-lcqrd4v0	49	17	and	and	CC
cord-017161-lcqrd4v0	49	18	DRB*07	drb*07	VB
cord-017161-lcqrd4v0	49	19	negatively	negatively	RB
cord-017161-lcqrd4v0	49	20	associated	associate	VBN
cord-017161-lcqrd4v0	49	21	,	,	,
cord-017161-lcqrd4v0	49	22	with	with	IN
cord-017161-lcqrd4v0	49	23	HSP	HSP	NNP
cord-017161-lcqrd4v0	49	24	in	in	IN
cord-017161-lcqrd4v0	49	25	two	two	CD
cord-017161-lcqrd4v0	49	26	of	of	IN
cord-017161-lcqrd4v0	49	27	the	the	DT
cord-017161-lcqrd4v0	49	28	three	three	CD
cord-017161-lcqrd4v0	49	29	studies	study	NNS
cord-017161-lcqrd4v0	49	30	[	[	-LRB-
cord-017161-lcqrd4v0	49	31	17	17	CD
cord-017161-lcqrd4v0	49	32	,	,	,
cord-017161-lcqrd4v0	49	33	18	18	CD
cord-017161-lcqrd4v0	49	34	,	,	,
cord-017161-lcqrd4v0	49	35	33	33	CD
cord-017161-lcqrd4v0	49	36	]	]	-RRB-
cord-017161-lcqrd4v0	49	37	.	.	.
cord-017161-lcqrd4v0	50	1	HLAB35	HLAB35	NNP
cord-017161-lcqrd4v0	50	2	was	be	VBD
cord-017161-lcqrd4v0	50	3	associated	associate	VBN
cord-017161-lcqrd4v0	50	4	with	with	IN
cord-017161-lcqrd4v0	50	5	HSP	HSP	NNP
cord-017161-lcqrd4v0	50	6	in	in	IN
cord-017161-lcqrd4v0	50	7	a	a	DT
cord-017161-lcqrd4v0	50	8	Turkish	turkish	JJ
cord-017161-lcqrd4v0	50	9	cohort	cohort	NN
cord-017161-lcqrd4v0	50	10	[	[	-LRB-
cord-017161-lcqrd4v0	50	11	19	19	CD
cord-017161-lcqrd4v0	50	12	]	]	-RRB-
cord-017161-lcqrd4v0	50	13	,	,	,
cord-017161-lcqrd4v0	50	14	but	but	CC
cord-017161-lcqrd4v0	50	15	was	be	VBD
cord-017161-lcqrd4v0	50	16	only	only	RB
cord-017161-lcqrd4v0	50	17	associated	associate	VBN
cord-017161-lcqrd4v0	50	18	with	with	IN
cord-017161-lcqrd4v0	50	19	nephritis	nephritis	NN
cord-017161-lcqrd4v0	50	20	in	in	IN
cord-017161-lcqrd4v0	50	21	a	a	DT
cord-017161-lcqrd4v0	50	22	Spanish	spanish	JJ
cord-017161-lcqrd4v0	50	23	cohort	cohort	NN
cord-017161-lcqrd4v0	50	24	[	[	-LRB-
cord-017161-lcqrd4v0	50	25	20	20	CD
cord-017161-lcqrd4v0	50	26	]	]	-RRB-
cord-017161-lcqrd4v0	50	27	.	.	.
cord-017161-lcqrd4v0	51	1	Null	Null	NNP
cord-017161-lcqrd4v0	51	2	alleles	allele	NNS
cord-017161-lcqrd4v0	51	3	in	in	IN
cord-017161-lcqrd4v0	51	4	either	either	DT
cord-017161-lcqrd4v0	51	5	of	of	IN
cord-017161-lcqrd4v0	51	6	the	the	DT
cord-017161-lcqrd4v0	51	7	complement	complement	NN
cord-017161-lcqrd4v0	51	8	factor	factor	NN
cord-017161-lcqrd4v0	51	9	C4	c4	NN
cord-017161-lcqrd4v0	51	10	genes	gene	NNS
cord-017161-lcqrd4v0	51	11	(	(	-LRB-
cord-017161-lcqrd4v0	51	12	C4A	c4a	NN
cord-017161-lcqrd4v0	51	13	or	or	CC
cord-017161-lcqrd4v0	51	14	C4B	c4b	NN
cord-017161-lcqrd4v0	51	15	)	)	-RRB-
cord-017161-lcqrd4v0	51	16	have	have	VBP
cord-017161-lcqrd4v0	51	17	shown	show	VBN
cord-017161-lcqrd4v0	51	18	associations	association	NNS
cord-017161-lcqrd4v0	51	19	with	with	IN
cord-017161-lcqrd4v0	51	20	HSP	HSP	NNP
cord-017161-lcqrd4v0	51	21	in	in	IN
cord-017161-lcqrd4v0	51	22	multiple	multiple	JJ
cord-017161-lcqrd4v0	51	23	cohorts	cohort	NNS
cord-017161-lcqrd4v0	51	24	of	of	IN
cord-017161-lcqrd4v0	51	25	different	different	JJ
cord-017161-lcqrd4v0	51	26	ethnicities	ethnicity	NNS
cord-017161-lcqrd4v0	51	27	[	[	-LRB-
cord-017161-lcqrd4v0	51	28	29	29	CD
cord-017161-lcqrd4v0	51	29	]	]	-RRB-
cord-017161-lcqrd4v0	51	30	,	,	,
cord-017161-lcqrd4v0	51	31	but	but	CC
cord-017161-lcqrd4v0	51	32	different	different	JJ
cord-017161-lcqrd4v0	51	33	fi	fi	NN
cord-017161-lcqrd4v0	51	34	ndings	nding	NNS
cord-017161-lcqrd4v0	51	35	regarding	regard	VBG
cord-017161-lcqrd4v0	51	36	associations	association	NNS
cord-017161-lcqrd4v0	51	37	with	with	IN
cord-017161-lcqrd4v0	51	38	C4A	c4a	CD
cord-017161-lcqrd4v0	51	39	or	or	CC
cord-017161-lcqrd4v0	51	40	C4B	c4b	NN
cord-017161-lcqrd4v0	51	41	alleles	allele	NNS
cord-017161-lcqrd4v0	51	42	,	,	,
cord-017161-lcqrd4v0	51	43	association	association	NN
cord-017161-lcqrd4v0	51	44	with	with	IN
cord-017161-lcqrd4v0	51	45	heterozygosity	heterozygosity	NN
cord-017161-lcqrd4v0	51	46	or	or	CC
cord-017161-lcqrd4v0	51	47	only	only	JJ
cord-017161-lcqrd4v0	51	48	homozygosity	homozygosity	NN
cord-017161-lcqrd4v0	51	49	for	for	IN
cord-017161-lcqrd4v0	51	50	a	a	DT
cord-017161-lcqrd4v0	51	51	null	null	JJ
cord-017161-lcqrd4v0	51	52	allele	allele	NN
cord-017161-lcqrd4v0	51	53	,	,	,
cord-017161-lcqrd4v0	51	54	and	and	CC
cord-017161-lcqrd4v0	51	55	close	close	JJ
cord-017161-lcqrd4v0	51	56	linkage	linkage	NN
cord-017161-lcqrd4v0	51	57	of	of	IN
cord-017161-lcqrd4v0	51	58	the	the	DT
cord-017161-lcqrd4v0	51	59	C4	c4	NN
cord-017161-lcqrd4v0	51	60	genes	gene	NNS
cord-017161-lcqrd4v0	51	61	to	to	IN
cord-017161-lcqrd4v0	51	62	HLA	HLA	NNP
cord-017161-lcqrd4v0	51	63	have	have	VBP
cord-017161-lcqrd4v0	51	64	resulted	result	VBN
cord-017161-lcqrd4v0	51	65	in	in	IN
cord-017161-lcqrd4v0	51	66	debate	debate	NN
cord-017161-lcqrd4v0	51	67	about	about	IN
cord-017161-lcqrd4v0	51	68	the	the	DT
cord-017161-lcqrd4v0	51	69	signi	signi	NNP
cord-017161-lcqrd4v0	51	70	fi	fi	NN
cord-017161-lcqrd4v0	51	71	cance	cance	NN
cord-017161-lcqrd4v0	51	72	of	of	IN
cord-017161-lcqrd4v0	51	73	these	these	DT
cord-017161-lcqrd4v0	51	74	fi	fi	NNP
cord-017161-lcqrd4v0	51	75	ndings	nding	NNS
cord-017161-lcqrd4v0	51	76	.	.	.
cord-017161-lcqrd4v0	52	1	Polymorphisms	polymorphism	NNS
cord-017161-lcqrd4v0	52	2	in	in	IN
cord-017161-lcqrd4v0	52	3	the	the	DT
cord-017161-lcqrd4v0	52	4	angiotensin	angiotensin	NN
cord-017161-lcqrd4v0	52	5	-	-	HYPH
cord-017161-lcqrd4v0	52	6	converting	convert	VBG
cord-017161-lcqrd4v0	52	7	enzyme	enzyme	NN
cord-017161-lcqrd4v0	52	8	(	(	-LRB-
cord-017161-lcqrd4v0	52	9	ACE	ace	NN
cord-017161-lcqrd4v0	52	10	)	)	-RRB-
cord-017161-lcqrd4v0	52	11	gene	gene	NN
cord-017161-lcqrd4v0	52	12	have	have	VBP
cord-017161-lcqrd4v0	52	13	been	be	VBN
cord-017161-lcqrd4v0	52	14	associated	associate	VBN
cord-017161-lcqrd4v0	52	15	with	with	IN
cord-017161-lcqrd4v0	52	16	risk	risk	NN
cord-017161-lcqrd4v0	52	17	of	of	IN
cord-017161-lcqrd4v0	52	18	HSP	HSP	NNP
cord-017161-lcqrd4v0	52	19	in	in	IN
cord-017161-lcqrd4v0	52	20	two	two	CD
cord-017161-lcqrd4v0	52	21	cohorts	cohort	NNS
cord-017161-lcqrd4v0	52	22	(	(	-LRB-
cord-017161-lcqrd4v0	52	23	OR	or	CC
cord-017161-lcqrd4v0	52	24	2.3	2.3	CD
cord-017161-lcqrd4v0	52	25	-	-	SYM
cord-017161-lcqrd4v0	52	26	2.7	2.7	CD
cord-017161-lcqrd4v0	52	27	)	)	-RRB-
cord-017161-lcqrd4v0	52	28	[	[	-LRB-
cord-017161-lcqrd4v0	52	29	24	24	CD
cord-017161-lcqrd4v0	52	30	,	,	,
cord-017161-lcqrd4v0	52	31	25	25	CD
cord-017161-lcqrd4v0	52	32	]	]	-RRB-
cord-017161-lcqrd4v0	52	33	;	;	:
cord-017161-lcqrd4v0	52	34	several	several	JJ
cord-017161-lcqrd4v0	52	35	additional	additional	JJ
cord-017161-lcqrd4v0	52	36	studies	study	NNS
cord-017161-lcqrd4v0	52	37	have	have	VBP
cord-017161-lcqrd4v0	52	38	focused	focus	VBN
cord-017161-lcqrd4v0	52	39	on	on	IN
cord-017161-lcqrd4v0	52	40	association	association	NN
cord-017161-lcqrd4v0	52	41	of	of	IN
cord-017161-lcqrd4v0	52	42	ACE	ACE	NNP
cord-017161-lcqrd4v0	52	43	alleles	allele	NNS
cord-017161-lcqrd4v0	52	44	with	with	IN
cord-017161-lcqrd4v0	52	45	risk	risk	NN
cord-017161-lcqrd4v0	52	46	of	of	IN
cord-017161-lcqrd4v0	52	47	nephritis	nephritis	NN
cord-017161-lcqrd4v0	52	48	but	but	CC
cord-017161-lcqrd4v0	52	49	without	without	IN
cord-017161-lcqrd4v0	52	50	consistent	consistent	JJ
cord-017161-lcqrd4v0	52	51	fi	fi	NNP
cord-017161-lcqrd4v0	52	52	ndings	nding	NNS
cord-017161-lcqrd4v0	52	53	.	.	.
cord-017161-lcqrd4v0	53	1	A	a	DT
cord-017161-lcqrd4v0	53	2	high	high	JJ
cord-017161-lcqrd4v0	53	3	carriage	carriage	NN
cord-017161-lcqrd4v0	53	4	rate	rate	NN
cord-017161-lcqrd4v0	53	5	of	of	IN
cord-017161-lcqrd4v0	53	6	mutations	mutation	NNS
cord-017161-lcqrd4v0	53	7	in	in	IN
cord-017161-lcqrd4v0	53	8	MEFV	MEFV	NNP
cord-017161-lcqrd4v0	53	9	was	be	VBD
cord-017161-lcqrd4v0	53	10	recently	recently	RB
cord-017161-lcqrd4v0	53	11	reported	report	VBN
cord-017161-lcqrd4v0	53	12	in	in	IN
cord-017161-lcqrd4v0	53	13	Turkish	turkish	JJ
cord-017161-lcqrd4v0	53	14	children	child	NNS
cord-017161-lcqrd4v0	53	15	with	with	IN
cord-017161-lcqrd4v0	53	16	HSP	HSP	NNP
cord-017161-lcqrd4v0	53	17	(	(	-LRB-
cord-017161-lcqrd4v0	53	18	OR	or	CC
cord-017161-lcqrd4v0	53	19	2.06	2.06	CD
cord-017161-lcqrd4v0	53	20	)	)	-RRB-
cord-017161-lcqrd4v0	54	1	[	[	-LRB-
cord-017161-lcqrd4v0	54	2	27	27	CD
cord-017161-lcqrd4v0	54	3	]	]	-RRB-
cord-017161-lcqrd4v0	54	4	.	.	.
cord-017161-lcqrd4v0	55	1	On	on	IN
cord-017161-lcqrd4v0	55	2	the	the	DT
cord-017161-lcqrd4v0	55	3	whole	whole	NN
cord-017161-lcqrd4v0	55	4	,	,	,
cord-017161-lcqrd4v0	55	5	however	however	RB
cord-017161-lcqrd4v0	55	6	,	,	,
cord-017161-lcqrd4v0	55	7	studies	study	NNS
cord-017161-lcqrd4v0	55	8	of	of	IN
cord-017161-lcqrd4v0	55	9	this	this	DT
cord-017161-lcqrd4v0	55	10	nature	nature	NN
cord-017161-lcqrd4v0	55	11	have	have	VBP
cord-017161-lcqrd4v0	55	12	been	be	VBN
cord-017161-lcqrd4v0	55	13	hampered	hamper	VBN
cord-017161-lcqrd4v0	55	14	by	by	IN
cord-017161-lcqrd4v0	55	15	relatively	relatively	RB
cord-017161-lcqrd4v0	55	16	small	small	JJ
cord-017161-lcqrd4v0	55	17	patient	patient	JJ
cord-017161-lcqrd4v0	55	18	numbers	number	NNS
cord-017161-lcqrd4v0	55	19	and	and	CC
cord-017161-lcqrd4v0	55	20	thus	thus	RB
cord-017161-lcqrd4v0	55	21	lack	lack	VBP
cord-017161-lcqrd4v0	55	22	the	the	DT
cord-017161-lcqrd4v0	55	23	power	power	NN
cord-017161-lcqrd4v0	55	24	to	to	TO
cord-017161-lcqrd4v0	55	25	be	be	VB
cord-017161-lcqrd4v0	55	26	de	de	FW
cord-017161-lcqrd4v0	55	27	fi	fi	NNP
cord-017161-lcqrd4v0	55	28	nitive	nitive	JJ
cord-017161-lcqrd4v0	55	29	or	or	CC
cord-017161-lcqrd4v0	55	30	necessarily	necessarily	RB
cord-017161-lcqrd4v0	55	31	applicable	applicable	JJ
cord-017161-lcqrd4v0	55	32	to	to	IN
cord-017161-lcqrd4v0	55	33	all	all	DT
cord-017161-lcqrd4v0	55	34	racial	racial	JJ
cord-017161-lcqrd4v0	55	35	groups	group	NNS
cord-017161-lcqrd4v0	55	36	.	.	.
cord-017161-lcqrd4v0	56	1	Skin	skin	NN
cord-017161-lcqrd4v0	56	2	involvement	involvement	NN
cord-017161-lcqrd4v0	56	3	is	be	VBZ
cord-017161-lcqrd4v0	56	4	typically	typically	RB
cord-017161-lcqrd4v0	56	5	with	with	IN
cord-017161-lcqrd4v0	56	6	purpura	purpura	NN
cord-017161-lcqrd4v0	56	7	,	,	,
cord-017161-lcqrd4v0	56	8	which	which	WDT
cord-017161-lcqrd4v0	56	9	is	be	VBZ
cord-017161-lcqrd4v0	56	10	generally	generally	RB
cord-017161-lcqrd4v0	56	11	symmetrical	symmetrical	JJ
cord-017161-lcqrd4v0	56	12	,	,	,
cord-017161-lcqrd4v0	56	13	affecting	affect	VBG
cord-017161-lcqrd4v0	56	14	the	the	DT
cord-017161-lcqrd4v0	56	15	lower	low	JJR
cord-017161-lcqrd4v0	56	16	limbs	limb	NNS
cord-017161-lcqrd4v0	56	17	and	and	CC
cord-017161-lcqrd4v0	56	18	buttocks	buttock	NNS
cord-017161-lcqrd4v0	56	19	in	in	IN
cord-017161-lcqrd4v0	56	20	the	the	DT
cord-017161-lcqrd4v0	56	21	majority	majority	NN
cord-017161-lcqrd4v0	56	22	of	of	IN
cord-017161-lcqrd4v0	56	23	cases	case	NNS
cord-017161-lcqrd4v0	56	24	,	,	,
cord-017161-lcqrd4v0	56	25	the	the	DT
cord-017161-lcqrd4v0	56	26	upper	upper	JJ
cord-017161-lcqrd4v0	56	27	extremities	extremity	NNS
cord-017161-lcqrd4v0	56	28	being	be	VBG
cord-017161-lcqrd4v0	56	29	involved	involve	VBN
cord-017161-lcqrd4v0	56	30	less	less	RBR
cord-017161-lcqrd4v0	56	31	frequently	frequently	RB
cord-017161-lcqrd4v0	56	32	[	[	-LRB-
cord-017161-lcqrd4v0	56	33	34	34	CD
cord-017161-lcqrd4v0	56	34	]	]	-RRB-
cord-017161-lcqrd4v0	56	35	.	.	.
cord-017161-lcqrd4v0	57	1	The	the	DT
cord-017161-lcqrd4v0	57	2	abdomen	abdomen	NN
cord-017161-lcqrd4v0	57	3	,	,	,
cord-017161-lcqrd4v0	57	4	chest	chest	NN
cord-017161-lcqrd4v0	57	5	and	and	CC
cord-017161-lcqrd4v0	57	6	face	face	NN
cord-017161-lcqrd4v0	57	7	are	be	VBP
cord-017161-lcqrd4v0	57	8	generally	generally	RB
cord-017161-lcqrd4v0	57	9	unaffected	unaffected	JJ
cord-017161-lcqrd4v0	57	10	[	[	-LRB-
cord-017161-lcqrd4v0	57	11	34	34	CD
cord-017161-lcqrd4v0	57	12	]	]	-RRB-
cord-017161-lcqrd4v0	57	13	.	.	.
cord-017161-lcqrd4v0	58	1	Angioedema	Angioedema	NNP
cord-017161-lcqrd4v0	58	2	and	and	CC
cord-017161-lcqrd4v0	58	3	urticaria	urticaria	NN
cord-017161-lcqrd4v0	58	4	can	can	MD
cord-017161-lcqrd4v0	58	5	also	also	RB
cord-017161-lcqrd4v0	58	6	occur	occur	VB
cord-017161-lcqrd4v0	58	7	[	[	-LRB-
cord-017161-lcqrd4v0	58	8	34	34	CD
cord-017161-lcqrd4v0	58	9	]	]	-RRB-
cord-017161-lcqrd4v0	58	10	.	.	.
cord-017161-lcqrd4v0	59	1	Around	around	IN
cord-017161-lcqrd4v0	59	2	two	two	CD
cord-017161-lcqrd4v0	59	3	thirds	third	NNS
cord-017161-lcqrd4v0	59	4	of	of	IN
cord-017161-lcqrd4v0	59	5	the	the	DT
cord-017161-lcqrd4v0	59	6	children	child	NNS
cord-017161-lcqrd4v0	59	7	have	have	VBP
cord-017161-lcqrd4v0	59	8	joint	joint	JJ
cord-017161-lcqrd4v0	59	9	manifestations	manifestation	NNS
cord-017161-lcqrd4v0	59	10	at	at	IN
cord-017161-lcqrd4v0	59	11	presentation	presentation	NN
cord-017161-lcqrd4v0	59	12	[	[	-LRB-
cord-017161-lcqrd4v0	59	13	34	34	CD
cord-017161-lcqrd4v0	59	14	]	]	-RRB-
cord-017161-lcqrd4v0	59	15	.	.	.
cord-017161-lcqrd4v0	60	1	Three	three	CD
cord-017161-lcqrd4v0	60	2	quarters	quarter	NNS
cord-017161-lcqrd4v0	60	3	of	of	IN
cord-017161-lcqrd4v0	60	4	the	the	DT
cord-017161-lcqrd4v0	60	5	children	child	NNS
cord-017161-lcqrd4v0	60	6	develop	develop	VB
cord-017161-lcqrd4v0	60	7	abdominal	abdominal	JJ
cord-017161-lcqrd4v0	60	8	symptoms	symptom	NNS
cord-017161-lcqrd4v0	60	9	ranging	range	VBG
cord-017161-lcqrd4v0	60	10	from	from	IN
cord-017161-lcqrd4v0	60	11	mild	mild	JJ
cord-017161-lcqrd4v0	60	12	colic	colic	NN
cord-017161-lcqrd4v0	60	13	to	to	IN
cord-017161-lcqrd4v0	60	14	severe	severe	JJ
cord-017161-lcqrd4v0	60	15	pain	pain	NN
cord-017161-lcqrd4v0	60	16	with	with	IN
cord-017161-lcqrd4v0	60	17	ileus	ileus	NN
cord-017161-lcqrd4v0	60	18	and	and	CC
cord-017161-lcqrd4v0	60	19	vomiting	vomit	VBG
cord-017161-lcqrd4v0	60	20	[	[	-LRB-
cord-017161-lcqrd4v0	60	21	34	34	CD
cord-017161-lcqrd4v0	60	22	]	]	-RRB-
cord-017161-lcqrd4v0	60	23	.	.	.
cord-017161-lcqrd4v0	61	1	Haematemesis	haematemesis	NN
cord-017161-lcqrd4v0	61	2	and	and	CC
cord-017161-lcqrd4v0	61	3	melena	melena	NN
cord-017161-lcqrd4v0	61	4	are	be	VBP
cord-017161-lcqrd4v0	61	5	sometimes	sometimes	RB
cord-017161-lcqrd4v0	61	6	observed	observe	VBN
cord-017161-lcqrd4v0	61	7	[	[	-LRB-
cord-017161-lcqrd4v0	61	8	34	34	CD
cord-017161-lcqrd4v0	61	9	]	]	-RRB-
cord-017161-lcqrd4v0	61	10	.	.	.
cord-017161-lcqrd4v0	62	1	Other	other	JJ
cord-017161-lcqrd4v0	62	2	complications	complication	NNS
cord-017161-lcqrd4v0	62	3	include	include	VBP
cord-017161-lcqrd4v0	62	4	intestinal	intestinal	JJ
cord-017161-lcqrd4v0	62	5	perforation	perforation	NN
cord-017161-lcqrd4v0	62	6	and	and	CC
cord-017161-lcqrd4v0	62	7	intussusception	intussusception	NN
cord-017161-lcqrd4v0	62	8	[	[	-LRB-
cord-017161-lcqrd4v0	62	9	34	34	CD
cord-017161-lcqrd4v0	62	10	]	]	-RRB-
cord-017161-lcqrd4v0	62	11	.	.	.
cord-017161-lcqrd4v0	63	1	Acute	acute	JJ
cord-017161-lcqrd4v0	63	2	pancreatitis	pancreatitis	NN
cord-017161-lcqrd4v0	63	3	is	be	VBZ
cord-017161-lcqrd4v0	63	4	also	also	RB
cord-017161-lcqrd4v0	63	5	described	describe	VBN
cord-017161-lcqrd4v0	63	6	,	,	,
cord-017161-lcqrd4v0	63	7	although	although	IN
cord-017161-lcqrd4v0	63	8	is	be	VBZ
cord-017161-lcqrd4v0	63	9	a	a	DT
cord-017161-lcqrd4v0	63	10	rare	rare	JJ
cord-017161-lcqrd4v0	63	11	complication	complication	NN
cord-017161-lcqrd4v0	63	12	[	[	-LRB-
cord-017161-lcqrd4v0	63	13	34	34	CD
cord-017161-lcqrd4v0	63	14	]	]	-RRB-
cord-017161-lcqrd4v0	63	15	.	.	.
cord-017161-lcqrd4v0	64	1	Other	other	JJ
cord-017161-lcqrd4v0	64	2	organs	organ	NNS
cord-017161-lcqrd4v0	64	3	less	less	RBR
cord-017161-lcqrd4v0	64	4	frequently	frequently	RB
cord-017161-lcqrd4v0	64	5	involved	involve	VBN
cord-017161-lcqrd4v0	64	6	include	include	VBP
cord-017161-lcqrd4v0	64	7	the	the	DT
cord-017161-lcqrd4v0	64	8	central	central	JJ
cord-017161-lcqrd4v0	64	9	nervous	nervous	JJ
cord-017161-lcqrd4v0	64	10	system	system	NN
cord-017161-lcqrd4v0	64	11	(	(	-LRB-
cord-017161-lcqrd4v0	64	12	cerebral	cerebral	JJ
cord-017161-lcqrd4v0	64	13	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	64	14	)	)	-RRB-
cord-017161-lcqrd4v0	64	15	,	,	,
cord-017161-lcqrd4v0	64	16	gonads	gonad	NNS
cord-017161-lcqrd4v0	64	17	(	(	-LRB-
cord-017161-lcqrd4v0	64	18	orchitis	orchitis	NN
cord-017161-lcqrd4v0	64	19	may	may	MD
cord-017161-lcqrd4v0	64	20	be	be	VB
cord-017161-lcqrd4v0	64	21	confused	confuse	VBN
cord-017161-lcqrd4v0	64	22	with	with	IN
cord-017161-lcqrd4v0	64	23	torsion	torsion	NN
cord-017161-lcqrd4v0	64	24	of	of	IN
cord-017161-lcqrd4v0	64	25	the	the	DT
cord-017161-lcqrd4v0	64	26	testis	testis	NN
cord-017161-lcqrd4v0	64	27	)	)	-RRB-
cord-017161-lcqrd4v0	64	28	and	and	CC
cord-017161-lcqrd4v0	64	29	the	the	DT
cord-017161-lcqrd4v0	64	30	lungs	lung	NNS
cord-017161-lcqrd4v0	64	31	(	(	-LRB-
cord-017161-lcqrd4v0	64	32	pulmonary	pulmonary	JJ
cord-017161-lcqrd4v0	64	33	haemorrhage	haemorrhage	NN
cord-017161-lcqrd4v0	64	34	)	)	-RRB-
cord-017161-lcqrd4v0	64	35	[	[	-LRB-
cord-017161-lcqrd4v0	64	36	34	34	CD
cord-017161-lcqrd4v0	64	37	]	]	-RRB-
cord-017161-lcqrd4v0	64	38	.	.	.
cord-017161-lcqrd4v0	65	1	Reports	report	NNS
cord-017161-lcqrd4v0	65	2	of	of	IN
cord-017161-lcqrd4v0	65	3	HSP	HSP	NNP
cord-017161-lcqrd4v0	65	4	nephritis	nephritis	NN
cord-017161-lcqrd4v0	65	5	indicate	indicate	VBP
cord-017161-lcqrd4v0	65	6	that	that	IN
cord-017161-lcqrd4v0	65	7	between	between	IN
cord-017161-lcqrd4v0	65	8	20	20	CD
cord-017161-lcqrd4v0	65	9	%	%	NN
cord-017161-lcqrd4v0	65	10	and	and	CC
cord-017161-lcqrd4v0	65	11	61	61	CD
cord-017161-lcqrd4v0	65	12	%	%	NN
cord-017161-lcqrd4v0	65	13	of	of	IN
cord-017161-lcqrd4v0	65	14	cases	case	NNS
cord-017161-lcqrd4v0	65	15	are	be	VBP
cord-017161-lcqrd4v0	65	16	affected	affect	VBN
cord-017161-lcqrd4v0	65	17	with	with	IN
cord-017161-lcqrd4v0	65	18	this	this	DT
cord-017161-lcqrd4v0	65	19	complication	complication	NN
cord-017161-lcqrd4v0	65	20	.	.	.
cord-017161-lcqrd4v0	66	1	Renal	renal	JJ
cord-017161-lcqrd4v0	66	2	involvement	involvement	NN
cord-017161-lcqrd4v0	66	3	can	can	MD
cord-017161-lcqrd4v0	66	4	present	present	VB
cord-017161-lcqrd4v0	66	5	with	with	IN
cord-017161-lcqrd4v0	66	6	varying	vary	VBG
cord-017161-lcqrd4v0	66	7	degrees	degree	NNS
cord-017161-lcqrd4v0	66	8	of	of	IN
cord-017161-lcqrd4v0	66	9	severity	severity	NN
cord-017161-lcqrd4v0	66	10	[	[	-LRB-
cord-017161-lcqrd4v0	66	11	34	34	CD
cord-017161-lcqrd4v0	66	12	]	]	-RRB-
cord-017161-lcqrd4v0	66	13	.	.	.
cord-017161-lcqrd4v0	67	1	This	this	DT
cord-017161-lcqrd4v0	67	2	includes	include	VBZ
cord-017161-lcqrd4v0	67	3	isolated	isolate	VBN
cord-017161-lcqrd4v0	67	4	microscopic	microscopic	JJ
cord-017161-lcqrd4v0	67	5	haematuria	haematuria	NNS
cord-017161-lcqrd4v0	67	6	,	,	,
cord-017161-lcqrd4v0	67	7	proteinuria	proteinuria	NN
cord-017161-lcqrd4v0	67	8	with	with	IN
cord-017161-lcqrd4v0	67	9	microscopic	microscopic	JJ
cord-017161-lcqrd4v0	67	10	or	or	CC
cord-017161-lcqrd4v0	67	11	macroscopic	macroscopic	JJ
cord-017161-lcqrd4v0	67	12	haematuria	haematuria	NNS
cord-017161-lcqrd4v0	67	13	,	,	,
cord-017161-lcqrd4v0	67	14	Polymorphisms	Polymorphisms	NNP
cord-017161-lcqrd4v0	67	15	in	in	IN
cord-017161-lcqrd4v0	67	16	PAX2	PAX2	NNP
cord-017161-lcqrd4v0	67	17	predispose	predispose	VB
cord-017161-lcqrd4v0	67	18	to	to	IN
cord-017161-lcqrd4v0	67	19	renal	renal	JJ
cord-017161-lcqrd4v0	67	20	involvement	involvement	NN
cord-017161-lcqrd4v0	67	21	in	in	IN
cord-017161-lcqrd4v0	67	22	HSP	HSP	NNP
cord-017161-lcqrd4v0	67	23	[	[	-LRB-
cord-017161-lcqrd4v0	67	24	30	30	CD
cord-017161-lcqrd4v0	67	25	]	]	-RRB-
cord-017161-lcqrd4v0	67	26	Nitric	nitric	NN
cord-017161-lcqrd4v0	67	27	oxide	oxide	NN
cord-017161-lcqrd4v0	67	28	and	and	CC
cord-017161-lcqrd4v0	67	29	associated	associate	VBD
cord-017161-lcqrd4v0	67	30	molecules	molecule	NNS
cord-017161-lcqrd4v0	68	1	Inducible	inducible	JJ
cord-017161-lcqrd4v0	68	2	nitric	nitric	JJ
cord-017161-lcqrd4v0	68	3	oxide	oxide	NN
cord-017161-lcqrd4v0	68	4	synthase	synthase	NN
cord-017161-lcqrd4v0	68	5	2A	2a	NN
cord-017161-lcqrd4v0	68	6	promoter	promoter	NN
cord-017161-lcqrd4v0	68	7	polymorphism	polymorphism	NN
cord-017161-lcqrd4v0	68	8	predisposes	predispose	VBZ
cord-017161-lcqrd4v0	68	9	to	to	IN
cord-017161-lcqrd4v0	68	10	renal	renal	JJ
cord-017161-lcqrd4v0	68	11	involvement	involvement	NN
cord-017161-lcqrd4v0	68	12	[	[	-LRB-
cord-017161-lcqrd4v0	68	13	31	31	CD
cord-017161-lcqrd4v0	68	14	]	]	-RRB-
cord-017161-lcqrd4v0	68	15	acute	acute	JJ
cord-017161-lcqrd4v0	68	16	nephritic	nephritic	JJ
cord-017161-lcqrd4v0	68	17	syndrome	syndrome	NN
cord-017161-lcqrd4v0	68	18	(	(	-LRB-
cord-017161-lcqrd4v0	68	19	haematuria	haematuria	NNP
cord-017161-lcqrd4v0	68	20	with	with	IN
cord-017161-lcqrd4v0	68	21	at	at	RB
cord-017161-lcqrd4v0	68	22	least	least	RBS
cord-017161-lcqrd4v0	68	23	two	two	CD
cord-017161-lcqrd4v0	68	24	of	of	IN
cord-017161-lcqrd4v0	68	25	hypertension	hypertension	NN
cord-017161-lcqrd4v0	68	26	,	,	,
cord-017161-lcqrd4v0	68	27	raised	raise	VBN
cord-017161-lcqrd4v0	68	28	plasma	plasma	NN
cord-017161-lcqrd4v0	68	29	creatinine	creatinine	NN
cord-017161-lcqrd4v0	68	30	and	and	CC
cord-017161-lcqrd4v0	68	31	oliguria	oliguria	NNP
cord-017161-lcqrd4v0	68	32	)	)	-RRB-
cord-017161-lcqrd4v0	68	33	,	,	,
cord-017161-lcqrd4v0	68	34	nephrotic	nephrotic	JJ
cord-017161-lcqrd4v0	68	35	syndrome	syndrome	NN
cord-017161-lcqrd4v0	68	36	(	(	-LRB-
cord-017161-lcqrd4v0	68	37	usually	usually	RB
cord-017161-lcqrd4v0	68	38	with	with	IN
cord-017161-lcqrd4v0	68	39	microscopic	microscopic	JJ
cord-017161-lcqrd4v0	68	40	haematuria	haematuria	NNS
cord-017161-lcqrd4v0	68	41	)	)	-RRB-
cord-017161-lcqrd4v0	68	42	or	or	CC
cord-017161-lcqrd4v0	68	43	a	a	DT
cord-017161-lcqrd4v0	68	44	mixed	mixed	JJ
cord-017161-lcqrd4v0	68	45	nephritic	nephritic	JJ
cord-017161-lcqrd4v0	68	46	-	-	HYPH
cord-017161-lcqrd4v0	68	47	nephrotic	nephrotic	JJ
cord-017161-lcqrd4v0	68	48	picture	picture	NN
cord-017161-lcqrd4v0	68	49	[	[	-LRB-
cord-017161-lcqrd4v0	68	50	34	34	CD
cord-017161-lcqrd4v0	68	51	]	]	-RRB-
cord-017161-lcqrd4v0	68	52	.	.	.
cord-017161-lcqrd4v0	69	1	The	the	DT
cord-017161-lcqrd4v0	69	2	large	large	JJ
cord-017161-lcqrd4v0	69	3	majority	majority	NN
cord-017161-lcqrd4v0	69	4	of	of	IN
cord-017161-lcqrd4v0	69	5	cases	case	NNS
cord-017161-lcqrd4v0	69	6	of	of	IN
cord-017161-lcqrd4v0	69	7	HSP	HSP	NNP
cord-017161-lcqrd4v0	69	8	require	require	VBP
cord-017161-lcqrd4v0	69	9	symptomatic	symptomatic	JJ
cord-017161-lcqrd4v0	69	10	treatment	treatment	NN
cord-017161-lcqrd4v0	69	11	only	only	RB
cord-017161-lcqrd4v0	69	12	[	[	-LRB-
cord-017161-lcqrd4v0	69	13	34	34	CD
cord-017161-lcqrd4v0	69	14	]	]	-RRB-
cord-017161-lcqrd4v0	69	15	.	.	.
cord-017161-lcqrd4v0	70	1	Nonsteroidal	nonsteroidal	JJ
cord-017161-lcqrd4v0	70	2	anti	anti	JJ
cord-017161-lcqrd4v0	70	3	-	-	NN
cord-017161-lcqrd4v0	70	4	in	in	IN
cord-017161-lcqrd4v0	70	5	fl	fl	NNP
cord-017161-lcqrd4v0	70	6	ammatory	ammatory	NNP
cord-017161-lcqrd4v0	70	7	drugs	drug	NNS
cord-017161-lcqrd4v0	70	8	(	(	-LRB-
cord-017161-lcqrd4v0	70	9	NSAIDs	nsaid	NNS
cord-017161-lcqrd4v0	70	10	)	)	-RRB-
cord-017161-lcqrd4v0	70	11	may	may	MD
cord-017161-lcqrd4v0	70	12	be	be	VB
cord-017161-lcqrd4v0	70	13	used	use	VBN
cord-017161-lcqrd4v0	70	14	to	to	TO
cord-017161-lcqrd4v0	70	15	treat	treat	VB
cord-017161-lcqrd4v0	70	16	arthralgia	arthralgia	NNP
cord-017161-lcqrd4v0	70	17	associated	associate	VBN
cord-017161-lcqrd4v0	70	18	with	with	IN
cord-017161-lcqrd4v0	70	19	HSP	HSP	NNP
cord-017161-lcqrd4v0	70	20	[	[	-LRB-
cord-017161-lcqrd4v0	70	21	34	34	CD
cord-017161-lcqrd4v0	70	22	]	]	-RRB-
cord-017161-lcqrd4v0	70	23	.	.	.
cord-017161-lcqrd4v0	71	1	Controversies	controversy	NNS
cord-017161-lcqrd4v0	71	2	concerning	concern	VBG
cord-017161-lcqrd4v0	71	3	the	the	DT
cord-017161-lcqrd4v0	71	4	use	use	NN
cord-017161-lcqrd4v0	71	5	of	of	IN
cord-017161-lcqrd4v0	71	6	corticosteroids	corticosteroid	NNS
cord-017161-lcqrd4v0	71	7	in	in	IN
cord-017161-lcqrd4v0	71	8	the	the	DT
cord-017161-lcqrd4v0	71	9	treatment	treatment	NN
cord-017161-lcqrd4v0	71	10	of	of	IN
cord-017161-lcqrd4v0	71	11	HSP	HSP	NNP
cord-017161-lcqrd4v0	71	12	exist	exist	VBP
cord-017161-lcqrd4v0	71	13	with	with	IN
cord-017161-lcqrd4v0	71	14	regard	regard	NN
cord-017161-lcqrd4v0	71	15	to	to	IN
cord-017161-lcqrd4v0	72	1	whether	whether	IN
cord-017161-lcqrd4v0	72	2	or	or	CC
cord-017161-lcqrd4v0	72	3	not	not	RB
cord-017161-lcqrd4v0	72	4	they	-PRON-	PRP
cord-017161-lcqrd4v0	72	5	can	can	MD
cord-017161-lcqrd4v0	72	6	(	(	-LRB-
cord-017161-lcqrd4v0	72	7	1	1	LS
cord-017161-lcqrd4v0	72	8	)	)	-RRB-
cord-017161-lcqrd4v0	72	9	reduce	reduce	VB
cord-017161-lcqrd4v0	72	10	severity	severity	NN
cord-017161-lcqrd4v0	72	11	or	or	CC
cord-017161-lcqrd4v0	72	12	duration	duration	NN
cord-017161-lcqrd4v0	72	13	of	of	IN
cord-017161-lcqrd4v0	72	14	disease	disease	NN
cord-017161-lcqrd4v0	72	15	,	,	,
cord-017161-lcqrd4v0	72	16	(	(	-LRB-
cord-017161-lcqrd4v0	72	17	2	2	LS
cord-017161-lcqrd4v0	72	18	)	)	-RRB-
cord-017161-lcqrd4v0	72	19	decrease	decrease	VB
cord-017161-lcqrd4v0	72	20	the	the	DT
cord-017161-lcqrd4v0	72	21	risk	risk	NN
cord-017161-lcqrd4v0	72	22	of	of	IN
cord-017161-lcqrd4v0	72	23	glomerulonephritis	glomerulonephritis	NN
cord-017161-lcqrd4v0	72	24	,	,	,
cord-017161-lcqrd4v0	72	25	and	and	CC
cord-017161-lcqrd4v0	72	26	(	(	-LRB-
cord-017161-lcqrd4v0	72	27	3	3	LS
cord-017161-lcqrd4v0	72	28	)	)	-RRB-
cord-017161-lcqrd4v0	72	29	prevent	prevent	VB
cord-017161-lcqrd4v0	72	30	relapses	relapse	NNS
cord-017161-lcqrd4v0	72	31	of	of	IN
cord-017161-lcqrd4v0	72	32	the	the	DT
cord-017161-lcqrd4v0	72	33	disease	disease	NN
cord-017161-lcqrd4v0	72	34	[	[	-LRB-
cord-017161-lcqrd4v0	72	35	35	35	CD
cord-017161-lcqrd4v0	72	36	,	,	,
cord-017161-lcqrd4v0	72	37	36	36	CD
cord-017161-lcqrd4v0	72	38	]	]	-RRB-
cord-017161-lcqrd4v0	72	39	.	.	.
cord-017161-lcqrd4v0	73	1	Chartapisak	Chartapisak	NNP
cord-017161-lcqrd4v0	73	2	et	et	FW
cord-017161-lcqrd4v0	73	3	al	al	NNP
cord-017161-lcqrd4v0	73	4	.	.	.
cord-017161-lcqrd4v0	74	1	recently	recently	RB
cord-017161-lcqrd4v0	74	2	systematically	systematically	RB
cord-017161-lcqrd4v0	74	3	reviewed	review	VBD
cord-017161-lcqrd4v0	74	4	all	all	DT
cord-017161-lcqrd4v0	74	5	published	publish	VBN
cord-017161-lcqrd4v0	74	6	randomized	randomized	JJ
cord-017161-lcqrd4v0	74	7	controlled	control	VBN
cord-017161-lcqrd4v0	74	8	trials	trial	NNS
cord-017161-lcqrd4v0	74	9	(	(	-LRB-
cord-017161-lcqrd4v0	74	10	RCTs	RCTs	NNP
cord-017161-lcqrd4v0	74	11	)	)	-RRB-
cord-017161-lcqrd4v0	74	12	for	for	IN
cord-017161-lcqrd4v0	74	13	the	the	DT
cord-017161-lcqrd4v0	74	14	prevention	prevention	NN
cord-017161-lcqrd4v0	74	15	or	or	CC
cord-017161-lcqrd4v0	74	16	treatment	treatment	NN
cord-017161-lcqrd4v0	74	17	of	of	IN
cord-017161-lcqrd4v0	74	18	renal	renal	JJ
cord-017161-lcqrd4v0	74	19	involvement	involvement	NN
cord-017161-lcqrd4v0	74	20	in	in	IN
cord-017161-lcqrd4v0	74	21	HSP	HSP	NNP
cord-017161-lcqrd4v0	74	22	[	[	-LRB-
cord-017161-lcqrd4v0	74	23	37	37	CD
cord-017161-lcqrd4v0	74	24	]	]	-RRB-
cord-017161-lcqrd4v0	74	25	.	.	.
cord-017161-lcqrd4v0	75	1	Meta	Meta	NNP
cord-017161-lcqrd4v0	75	2	-	-	HYPH
cord-017161-lcqrd4v0	75	3	analyses	analysis	NNS
cord-017161-lcqrd4v0	75	4	of	of	IN
cord-017161-lcqrd4v0	75	5	four	four	CD
cord-017161-lcqrd4v0	75	6	RCTs	rct	NNS
cord-017161-lcqrd4v0	75	7	,	,	,
cord-017161-lcqrd4v0	75	8	which	which	WDT
cord-017161-lcqrd4v0	75	9	evaluated	evaluate	VBD
cord-017161-lcqrd4v0	75	10	prednisone	prednisone	NNP
cord-017161-lcqrd4v0	75	11	therapy	therapy	NN
cord-017161-lcqrd4v0	75	12	at	at	IN
cord-017161-lcqrd4v0	75	13	presentation	presentation	NN
cord-017161-lcqrd4v0	75	14	of	of	IN
cord-017161-lcqrd4v0	75	15	HSP	HSP	NNP
cord-017161-lcqrd4v0	75	16	,	,	,
cord-017161-lcqrd4v0	75	17	showed	show	VBD
cord-017161-lcqrd4v0	75	18	that	that	IN
cord-017161-lcqrd4v0	75	19	there	there	EX
cord-017161-lcqrd4v0	75	20	was	be	VBD
cord-017161-lcqrd4v0	75	21	no	no	DT
cord-017161-lcqrd4v0	75	22	signi	signi	NN
cord-017161-lcqrd4v0	75	23	fi	fi	NN
cord-017161-lcqrd4v0	75	24	ca	can	MD
cord-017161-lcqrd4v0	75	25	nt	not	RB
cord-017161-lcqrd4v0	75	26	difference	difference	VB
cord-017161-lcqrd4v0	75	27	in	in	IN
cord-017161-lcqrd4v0	75	28	the	the	DT
cord-017161-lcqrd4v0	75	29	risk	risk	NN
cord-017161-lcqrd4v0	75	30	of	of	IN
cord-017161-lcqrd4v0	75	31	development	development	NN
cord-017161-lcqrd4v0	75	32	or	or	CC
cord-017161-lcqrd4v0	75	33	persistence	persistence	NN
cord-017161-lcqrd4v0	75	34	of	of	IN
cord-017161-lcqrd4v0	75	35	renal	renal	JJ
cord-017161-lcqrd4v0	75	36	involvement	involvement	NN
cord-017161-lcqrd4v0	75	37	at	at	IN
cord-017161-lcqrd4v0	75	38	1	1	CD
cord-017161-lcqrd4v0	75	39	,	,	,
cord-017161-lcqrd4v0	75	40	3	3	CD
cord-017161-lcqrd4v0	75	41	,	,	,
cord-017161-lcqrd4v0	75	42	6	6	CD
cord-017161-lcqrd4v0	75	43	and	and	CC
cord-017161-lcqrd4v0	75	44	12	12	CD
cord-017161-lcqrd4v0	75	45	months	month	NNS
cord-017161-lcqrd4v0	75	46	with	with	IN
cord-017161-lcqrd4v0	75	47	prednisone	prednisone	NN
cord-017161-lcqrd4v0	75	48	compared	compare	VBN
cord-017161-lcqrd4v0	75	49	with	with	IN
cord-017161-lcqrd4v0	75	50	placebo	placebo	NN
cord-017161-lcqrd4v0	75	51	or	or	CC
cord-017161-lcqrd4v0	75	52	no	no	DT
cord-017161-lcqrd4v0	75	53	speci	speci	XX
cord-017161-lcqrd4v0	75	54	fi	fi	NN
cord-017161-lcqrd4v0	75	55	c	c	NN
cord-017161-lcqrd4v0	75	56	treatment	treatment	NN
cord-017161-lcqrd4v0	75	57	[	[	-LRB-
cord-017161-lcqrd4v0	75	58	37	37	CD
cord-017161-lcqrd4v0	75	59	]	]	-RRB-
cord-017161-lcqrd4v0	75	60	.	.	.
cord-017161-lcqrd4v0	76	1	In	in	IN
cord-017161-lcqrd4v0	76	2	the	the	DT
cord-017161-lcqrd4v0	76	3	largest	large	JJS
cord-017161-lcqrd4v0	76	4	of	of	IN
cord-017161-lcqrd4v0	76	5	these	these	DT
cord-017161-lcqrd4v0	76	6	trials	trial	NNS
cord-017161-lcqrd4v0	76	7	,	,	,
cord-017161-lcqrd4v0	76	8	which	which	WDT
cord-017161-lcqrd4v0	76	9	enrolled	enrol	VBD
cord-017161-lcqrd4v0	76	10	children	child	NNS
cord-017161-lcqrd4v0	76	11	between	between	IN
cord-017161-lcqrd4v0	76	12	January	January	NNP
cord-017161-lcqrd4v0	76	13	2001	2001	CD
cord-017161-lcqrd4v0	76	14	and	and	CC
cord-017161-lcqrd4v0	76	15	January	January	NNP
cord-017161-lcqrd4v0	76	16	2005	2005	CD
cord-017161-lcqrd4v0	76	17	,	,	,
cord-017161-lcqrd4v0	76	18	the	the	DT
cord-017161-lcqrd4v0	76	19	primary	primary	JJ
cord-017161-lcqrd4v0	76	20	outcome	outcome	NN
cord-017161-lcqrd4v0	76	21	(	(	-LRB-
cord-017161-lcqrd4v0	76	22	urinary	urinary	JJ
cord-017161-lcqrd4v0	76	23	protein	protein	NN
cord-017161-lcqrd4v0	76	24	/	/	SYM
cord-017161-lcqrd4v0	76	25	creatinine	creatinine	NN
cord-017161-lcqrd4v0	76	26	ratio	ratio	NN
cord-017161-lcqrd4v0	76	27	at	at	IN
cord-017161-lcqrd4v0	76	28	1	1	CD
cord-017161-lcqrd4v0	76	29	year	year	NN
cord-017161-lcqrd4v0	76	30	)	)	-RRB-
cord-017161-lcqrd4v0	76	31	was	be	VBD
cord-017161-lcqrd4v0	76	32	measured	measure	VBN
cord-017161-lcqrd4v0	76	33	in	in	IN
cord-017161-lcqrd4v0	76	34	290	290	CD
cord-017161-lcqrd4v0	76	35	children	child	NNS
cord-017161-lcqrd4v0	76	36	[	[	-LRB-
cord-017161-lcqrd4v0	76	37	38	38	CD
cord-017161-lcqrd4v0	76	38	]	]	-RRB-
cord-017161-lcqrd4v0	76	39	.	.	.
cord-017161-lcqrd4v0	77	1	This	this	DT
cord-017161-lcqrd4v0	77	2	is	be	VBZ
cord-017161-lcqrd4v0	77	3	the	the	DT
cord-017161-lcqrd4v0	77	4	largest	large	JJS
cord-017161-lcqrd4v0	77	5	study	study	NN
cord-017161-lcqrd4v0	77	6	to	to	IN
cord-017161-lcqrd4v0	77	7	date	date	NN
cord-017161-lcqrd4v0	77	8	showing	show	VBG
cord-017161-lcqrd4v0	77	9	no	no	DT
cord-017161-lcqrd4v0	77	10	signi	signi	NN
cord-017161-lcqrd4v0	77	11	fi	fi	NN
cord-017161-lcqrd4v0	77	12	ca	can	MD
cord-017161-lcqrd4v0	77	13	nt	not	RB
cord-017161-lcqrd4v0	77	14	bene	bene	NNP
cord-017161-lcqrd4v0	77	15	fi	fi	NNP
cord-017161-lcqrd4v0	77	16	t	t	NN
cord-017161-lcqrd4v0	77	17	of	of	IN
cord-017161-lcqrd4v0	77	18	prednisone	prednisone	NNP
cord-017161-lcqrd4v0	77	19	over	over	IN
cord-017161-lcqrd4v0	77	20	placebo	placebo	NN
cord-017161-lcqrd4v0	77	21	in	in	IN
cord-017161-lcqrd4v0	77	22	preventing	prevent	VBG
cord-017161-lcqrd4v0	77	23	persistent	persistent	JJ
cord-017161-lcqrd4v0	77	24	renal	renal	JJ
cord-017161-lcqrd4v0	77	25	disease	disease	NN
cord-017161-lcqrd4v0	77	26	[	[	-LRB-
cord-017161-lcqrd4v0	77	27	38	38	CD
cord-017161-lcqrd4v0	77	28	]	]	-RRB-
cord-017161-lcqrd4v0	77	29	.	.	.
cord-017161-lcqrd4v0	78	1	That	that	DT
cord-017161-lcqrd4v0	78	2	said	say	VBD
cord-017161-lcqrd4v0	78	3	,	,	,
cord-017161-lcqrd4v0	78	4	there	there	EX
cord-017161-lcqrd4v0	78	5	could	could	MD
cord-017161-lcqrd4v0	78	6	still	still	RB
cord-017161-lcqrd4v0	78	7	be	be	VB
cord-017161-lcqrd4v0	78	8	a	a	DT
cord-017161-lcqrd4v0	78	9	role	role	NN
cord-017161-lcqrd4v0	78	10	for	for	IN
cord-017161-lcqrd4v0	78	11	early	early	JJ
cord-017161-lcqrd4v0	78	12	use	use	NN
cord-017161-lcqrd4v0	78	13	of	of	IN
cord-017161-lcqrd4v0	78	14	corticosteroids	corticosteroid	NNS
cord-017161-lcqrd4v0	78	15	in	in	IN
cord-017161-lcqrd4v0	78	16	patients	patient	NNS
cord-017161-lcqrd4v0	78	17	with	with	IN
cord-017161-lcqrd4v0	78	18	severe	severe	JJ
cord-017161-lcqrd4v0	78	19	extrarenal	extrarenal	JJ
cord-017161-lcqrd4v0	78	20	symptoms	symptom	NNS
cord-017161-lcqrd4v0	78	21	such	such	JJ
cord-017161-lcqrd4v0	78	22	as	as	IN
cord-017161-lcqrd4v0	78	23	abdominal	abdominal	JJ
cord-017161-lcqrd4v0	78	24	pain	pain	NN
cord-017161-lcqrd4v0	78	25	and	and	CC
cord-017161-lcqrd4v0	78	26	arthralgia	arthralgia	NN
cord-017161-lcqrd4v0	78	27	,	,	,
cord-017161-lcqrd4v0	78	28	as	as	IN
cord-017161-lcqrd4v0	78	29	suggested	suggest	VBN
cord-017161-lcqrd4v0	78	30	by	by	IN
cord-017161-lcqrd4v0	78	31	the	the	DT
cord-017161-lcqrd4v0	78	32	fi	fi	NNP
cord-017161-lcqrd4v0	78	33	ndings	nding	NNS
cord-017161-lcqrd4v0	78	34	of	of	IN
cord-017161-lcqrd4v0	78	35	a	a	DT
cord-017161-lcqrd4v0	78	36	study	study	NN
cord-017161-lcqrd4v0	78	37	performed	perform	VBN
cord-017161-lcqrd4v0	78	38	by	by	IN
cord-017161-lcqrd4v0	78	39	Ronkainen	Ronkainen	NNP
cord-017161-lcqrd4v0	78	40	et	et	NNP
cord-017161-lcqrd4v0	78	41	al	al	NNP
cord-017161-lcqrd4v0	78	42	.	.	.
cord-017161-lcqrd4v0	79	1	[	[	-LRB-
cord-017161-lcqrd4v0	79	2	36	36	CD
cord-017161-lcqrd4v0	79	3	]	]	-RRB-
cord-017161-lcqrd4v0	79	4	.	.	.
cord-017161-lcqrd4v0	80	1	Prednisone	Prednisone	NNP
cord-017161-lcqrd4v0	80	2	(	(	-LRB-
cord-017161-lcqrd4v0	80	3	1	1	CD
cord-017161-lcqrd4v0	80	4	mg	mg	NNP
cord-017161-lcqrd4v0	80	5	/	/	SYM
cord-017161-lcqrd4v0	80	6	kg	kg	NNP
cord-017161-lcqrd4v0	80	7	/	/	SYM
cord-017161-lcqrd4v0	80	8	day	day	NN
cord-017161-lcqrd4v0	80	9	for	for	IN
cord-017161-lcqrd4v0	80	10	2	2	CD
cord-017161-lcqrd4v0	80	11	weeks	week	NNS
cord-017161-lcqrd4v0	80	12	,	,	,
cord-017161-lcqrd4v0	80	13	with	with	IN
cord-017161-lcqrd4v0	80	14	weaning	wean	VBG
cord-017161-lcqrd4v0	80	15	over	over	IN
cord-017161-lcqrd4v0	80	16	the	the	DT
cord-017161-lcqrd4v0	80	17	subsequent	subsequent	JJ
cord-017161-lcqrd4v0	80	18	2	2	CD
cord-017161-lcqrd4v0	80	19	weeks	week	NNS
cord-017161-lcqrd4v0	80	20	)	)	-RRB-
cord-017161-lcqrd4v0	80	21	was	be	VBD
cord-017161-lcqrd4v0	80	22	effective	effective	JJ
cord-017161-lcqrd4v0	80	23	in	in	IN
cord-017161-lcqrd4v0	80	24	reducing	reduce	VBG
cord-017161-lcqrd4v0	80	25	the	the	DT
cord-017161-lcqrd4v0	80	26	intensity	intensity	NN
cord-017161-lcqrd4v0	80	27	of	of	IN
cord-017161-lcqrd4v0	80	28	abdominal	abdominal	JJ
cord-017161-lcqrd4v0	80	29	pain	pain	NN
cord-017161-lcqrd4v0	80	30	and	and	CC
cord-017161-lcqrd4v0	80	31	joint	joint	JJ
cord-017161-lcqrd4v0	80	32	pain	pain	NN
cord-017161-lcqrd4v0	80	33	[	[	-LRB-
cord-017161-lcqrd4v0	80	34	36	36	CD
cord-017161-lcqrd4v0	80	35	]	]	-RRB-
cord-017161-lcqrd4v0	80	36	.	.	.
cord-017161-lcqrd4v0	81	1	Prednisone	Prednisone	NNP
cord-017161-lcqrd4v0	81	2	did	do	VBD
cord-017161-lcqrd4v0	81	3	not	not	RB
cord-017161-lcqrd4v0	81	4	prevent	prevent	VB
cord-017161-lcqrd4v0	81	5	the	the	DT
cord-017161-lcqrd4v0	81	6	development	development	NN
cord-017161-lcqrd4v0	81	7	of	of	IN
cord-017161-lcqrd4v0	81	8	renal	renal	JJ
cord-017161-lcqrd4v0	81	9	symptoms	symptom	NNS
cord-017161-lcqrd4v0	81	10	but	but	CC
cord-017161-lcqrd4v0	81	11	was	be	VBD
cord-017161-lcqrd4v0	81	12	effective	effective	JJ
cord-017161-lcqrd4v0	81	13	in	in	IN
cord-017161-lcqrd4v0	81	14	treating	treat	VBG
cord-017161-lcqrd4v0	81	15	them	-PRON-	PRP
cord-017161-lcqrd4v0	81	16	if	if	IN
cord-017161-lcqrd4v0	81	17	present	present	JJ
cord-017161-lcqrd4v0	81	18	;	;	:
cord-017161-lcqrd4v0	81	19	renal	renal	JJ
cord-017161-lcqrd4v0	81	20	symptoms	symptom	NNS
cord-017161-lcqrd4v0	81	21	resolved	resolve	VBN
cord-017161-lcqrd4v0	81	22	in	in	IN
cord-017161-lcqrd4v0	81	23	61	61	CD
cord-017161-lcqrd4v0	81	24	%	%	NN
cord-017161-lcqrd4v0	81	25	of	of	IN
cord-017161-lcqrd4v0	81	26	the	the	DT
cord-017161-lcqrd4v0	81	27	prednisone	prednisone	JJ
cord-017161-lcqrd4v0	81	28	patients	patient	NNS
cord-017161-lcqrd4v0	81	29	after	after	IN
cord-017161-lcqrd4v0	81	30	treatment	treatment	NN
cord-017161-lcqrd4v0	81	31	,	,	,
cord-017161-lcqrd4v0	81	32	compared	compare	VBN
cord-017161-lcqrd4v0	81	33	with	with	IN
cord-017161-lcqrd4v0	81	34	34	34	CD
cord-017161-lcqrd4v0	81	35	%	%	NN
cord-017161-lcqrd4v0	81	36	of	of	IN
cord-017161-lcqrd4v0	81	37	the	the	DT
cord-017161-lcqrd4v0	81	38	placebo	placebo	NN
cord-017161-lcqrd4v0	81	39	patients	patient	NNS
cord-017161-lcqrd4v0	81	40	[	[	-LRB-
cord-017161-lcqrd4v0	81	41	36	36	CD
cord-017161-lcqrd4v0	81	42	]	]	-RRB-
cord-017161-lcqrd4v0	81	43	.	.	.
cord-017161-lcqrd4v0	82	1	Of	of	IN
cord-017161-lcqrd4v0	82	2	note	note	NN
cord-017161-lcqrd4v0	82	3	,	,	,
cord-017161-lcqrd4v0	82	4	Nikibakhsh	Nikibakhsh	NNP
cord-017161-lcqrd4v0	82	5	et	et	NNP
cord-017161-lcqrd4v0	82	6	al	al	NNP
cord-017161-lcqrd4v0	82	7	.	.	NNP
cord-017161-lcqrd4v0	82	8	reported	report	VBN
cord-017161-lcqrd4v0	82	9	recently	recently	RB
cord-017161-lcqrd4v0	82	10	on	on	IN
cord-017161-lcqrd4v0	82	11	the	the	DT
cord-017161-lcqrd4v0	82	12	successful	successful	JJ
cord-017161-lcqrd4v0	82	13	treatment	treatment	NN
cord-017161-lcqrd4v0	82	14	with	with	IN
cord-017161-lcqrd4v0	82	15	mycophenolate	mycophenolate	NNP
cord-017161-lcqrd4v0	82	16	mofetil	mofetil	NNP
cord-017161-lcqrd4v0	82	17	(	(	-LRB-
cord-017161-lcqrd4v0	82	18	MMF	MMF	NNP
cord-017161-lcqrd4v0	82	19	)	)	-RRB-
cord-017161-lcqrd4v0	82	20	of	of	IN
cord-017161-lcqrd4v0	82	21	recurrent	recurrent	JJ
cord-017161-lcqrd4v0	82	22	skin	skin	NN
cord-017161-lcqrd4v0	82	23	,	,	,
cord-017161-lcqrd4v0	82	24	articular	articular	JJ
cord-017161-lcqrd4v0	82	25	and	and	CC
cord-017161-lcqrd4v0	82	26	gastrointestinal	gastrointestinal	JJ
cord-017161-lcqrd4v0	82	27	symptoms	symptom	NNS
cord-017161-lcqrd4v0	82	28	in	in	IN
cord-017161-lcqrd4v0	82	29	children	child	NNS
cord-017161-lcqrd4v0	82	30	with	with	IN
cord-017161-lcqrd4v0	82	31	who	who	WP
cord-017161-lcqrd4v0	82	32	failed	fail	VBD
cord-017161-lcqrd4v0	82	33	to	to	TO
cord-017161-lcqrd4v0	82	34	respond	respond	VB
cord-017161-lcqrd4v0	82	35	to	to	IN
cord-017161-lcqrd4v0	82	36	systemic	systemic	JJ
cord-017161-lcqrd4v0	82	37	steroid	steroid	NN
cord-017161-lcqrd4v0	82	38	therapy	therapy	NN
cord-017161-lcqrd4v0	82	39	[	[	-LRB-
cord-017161-lcqrd4v0	82	40	39	39	CD
cord-017161-lcqrd4v0	82	41	]	]	-RRB-
cord-017161-lcqrd4v0	82	42	.	.	.
cord-017161-lcqrd4v0	83	1	For	for	IN
cord-017161-lcqrd4v0	83	2	patients	patient	NNS
cord-017161-lcqrd4v0	83	3	with	with	IN
cord-017161-lcqrd4v0	83	4	rapidly	rapidly	RB
cord-017161-lcqrd4v0	83	5	progressive	progressive	JJ
cord-017161-lcqrd4v0	83	6	glomerulonephritis	glomerulonephritis	NN
cord-017161-lcqrd4v0	83	7	with	with	IN
cord-017161-lcqrd4v0	83	8	crescentic	crescentic	JJ
cord-017161-lcqrd4v0	83	9	change	change	NN
cord-017161-lcqrd4v0	83	10	on	on	IN
cord-017161-lcqrd4v0	83	11	biopsy	biopsy	NN
cord-017161-lcqrd4v0	83	12	,	,	,
cord-017161-lcqrd4v0	83	13	uncontrolled	uncontrolled	JJ
cord-017161-lcqrd4v0	83	14	data	datum	NNS
cord-017161-lcqrd4v0	83	15	suggest	suggest	VBP
cord-017161-lcqrd4v0	83	16	that	that	IN
cord-017161-lcqrd4v0	83	17	treatment	treatment	NN
cord-017161-lcqrd4v0	83	18	may	may	MD
cord-017161-lcqrd4v0	83	19	comprise	comprise	VB
cord-017161-lcqrd4v0	83	20	aggressive	aggressive	JJ
cord-017161-lcqrd4v0	83	21	therapy	therapy	NN
cord-017161-lcqrd4v0	83	22	with	with	IN
cord-017161-lcqrd4v0	83	23	corticosteroid	corticosteroid	NN
cord-017161-lcqrd4v0	83	24	,	,	,
cord-017161-lcqrd4v0	83	25	cyclophosphamide	cyclophosphamide	RB
cord-017161-lcqrd4v0	83	26	and	and	CC
cord-017161-lcqrd4v0	83	27	possibly	possibly	RB
cord-017161-lcqrd4v0	83	28	plasma	plasma	VB
cord-017161-lcqrd4v0	83	29	exchange	exchange	NN
cord-017161-lcqrd4v0	83	30	[	[	-LRB-
cord-017161-lcqrd4v0	83	31	34	34	CD
cord-017161-lcqrd4v0	83	32	]	]	-RRB-
cord-017161-lcqrd4v0	83	33	,	,	,
cord-017161-lcqrd4v0	83	34	as	as	IN
cord-017161-lcqrd4v0	83	35	with	with	IN
cord-017161-lcqrd4v0	83	36	other	other	JJ
cord-017161-lcqrd4v0	83	37	causes	cause	NNS
cord-017161-lcqrd4v0	83	38	of	of	IN
cord-017161-lcqrd4v0	83	39	crescentic	crescentic	JJ
cord-017161-lcqrd4v0	83	40	nephritis	nephritis	NN
cord-017161-lcqrd4v0	83	41	.	.	.
cord-017161-lcqrd4v0	84	1	Other	other	JJ
cord-017161-lcqrd4v0	84	2	therapies	therapy	NNS
cord-017161-lcqrd4v0	84	3	such	such	JJ
cord-017161-lcqrd4v0	84	4	as	as	IN
cord-017161-lcqrd4v0	84	5	cyclosporin	cyclosporin	NN
cord-017161-lcqrd4v0	84	6	,	,	,
cord-017161-lcqrd4v0	84	7	azathioprine	azathioprine	JJ
cord-017161-lcqrd4v0	84	8	and	and	CC
cord-017161-lcqrd4v0	84	9	cyclophosphamide	cyclophosphamide	RB
cord-017161-lcqrd4v0	84	10	have	have	VBP
cord-017161-lcqrd4v0	84	11	been	be	VBN
cord-017161-lcqrd4v0	84	12	reported	report	VBN
cord-017161-lcqrd4v0	84	13	to	to	TO
cord-017161-lcqrd4v0	84	14	be	be	VB
cord-017161-lcqrd4v0	84	15	effective	effective	JJ
cord-017161-lcqrd4v0	84	16	[	[	-LRB-
cord-017161-lcqrd4v0	84	17	40	40	CD
cord-017161-lcqrd4v0	84	18	]	]	-RRB-
cord-017161-lcqrd4v0	84	19	[	[	-LRB-
cord-017161-lcqrd4v0	84	20	41	41	CD
cord-017161-lcqrd4v0	84	21	]	]	-RRB-
cord-017161-lcqrd4v0	84	22	[	[	-LRB-
cord-017161-lcqrd4v0	84	23	42	42	CD
cord-017161-lcqrd4v0	84	24	]	]	-RRB-
cord-017161-lcqrd4v0	84	25	.	.	.
cord-017161-lcqrd4v0	85	1	As	as	IN
cord-017161-lcqrd4v0	85	2	HSP	HSP	NNP
cord-017161-lcqrd4v0	85	3	is	be	VBZ
cord-017161-lcqrd4v0	85	4	the	the	DT
cord-017161-lcqrd4v0	85	5	most	most	RBS
cord-017161-lcqrd4v0	85	6	common	common	JJ
cord-017161-lcqrd4v0	85	7	cause	cause	NN
cord-017161-lcqrd4v0	85	8	of	of	IN
cord-017161-lcqrd4v0	85	9	rapidly	rapidly	RB
cord-017161-lcqrd4v0	85	10	progressive	progressive	JJ
cord-017161-lcqrd4v0	85	11	glomerulonephritis	glomerulonephritis	NN
cord-017161-lcqrd4v0	85	12	in	in	IN
cord-017161-lcqrd4v0	85	13	childhood	childhood	NN
cord-017161-lcqrd4v0	85	14	,	,	,
cord-017161-lcqrd4v0	85	15	more	more	RBR
cord-017161-lcqrd4v0	85	16	aggressive	aggressive	JJ
cord-017161-lcqrd4v0	85	17	therapeutic	therapeutic	JJ
cord-017161-lcqrd4v0	85	18	approaches	approach	NNS
cord-017161-lcqrd4v0	85	19	such	such	JJ
cord-017161-lcqrd4v0	85	20	as	as	IN
cord-017161-lcqrd4v0	85	21	plasma	plasma	NN
cord-017161-lcqrd4v0	85	22	exchange	exchange	NN
cord-017161-lcqrd4v0	85	23	have	have	VBP
cord-017161-lcqrd4v0	85	24	been	be	VBN
cord-017161-lcqrd4v0	85	25	employed	employ	VBN
cord-017161-lcqrd4v0	85	26	in	in	IN
cord-017161-lcqrd4v0	85	27	some	some	DT
cord-017161-lcqrd4v0	85	28	cases	case	NNS
cord-017161-lcqrd4v0	85	29	[	[	-LRB-
cord-017161-lcqrd4v0	85	30	43	43	CD
cord-017161-lcqrd4v0	85	31	]	]	-RRB-
cord-017161-lcqrd4v0	85	32	.	.	.
cord-017161-lcqrd4v0	86	1	These	these	DT
cord-017161-lcqrd4v0	86	2	treatment	treatment	NN
cord-017161-lcqrd4v0	86	3	options	option	NNS
cord-017161-lcqrd4v0	86	4	,	,	,
cord-017161-lcqrd4v0	86	5	while	while	IN
cord-017161-lcqrd4v0	86	6	important	important	JJ
cord-017161-lcqrd4v0	86	7	in	in	IN
cord-017161-lcqrd4v0	86	8	select	select	JJ
cord-017161-lcqrd4v0	86	9	cases	case	NNS
cord-017161-lcqrd4v0	86	10	,	,	,
cord-017161-lcqrd4v0	86	11	are	be	VBP
cord-017161-lcqrd4v0	86	12	not	not	RB
cord-017161-lcqrd4v0	86	13	yet	yet	RB
cord-017161-lcqrd4v0	86	14	supported	support	VBN
cord-017161-lcqrd4v0	86	15	by	by	IN
cord-017161-lcqrd4v0	86	16	RCTs	rct	NNS
cord-017161-lcqrd4v0	86	17	.	.	.
cord-017161-lcqrd4v0	87	1	In	in	IN
cord-017161-lcqrd4v0	87	2	addition	addition	NN
cord-017161-lcqrd4v0	87	3	,	,	,
cord-017161-lcqrd4v0	87	4	there	there	EX
cord-017161-lcqrd4v0	87	5	are	be	VBP
cord-017161-lcqrd4v0	87	6	no	no	DT
cord-017161-lcqrd4v0	87	7	robust	robust	JJ
cord-017161-lcqrd4v0	87	8	clinical	clinical	JJ
cord-017161-lcqrd4v0	87	9	trials	trial	NNS
cord-017161-lcqrd4v0	87	10	to	to	TO
cord-017161-lcqrd4v0	87	11	guide	guide	VB
cord-017161-lcqrd4v0	87	12	therapy	therapy	NN
cord-017161-lcqrd4v0	87	13	for	for	IN
cord-017161-lcqrd4v0	87	14	HSP	HSP	NNP
cord-017161-lcqrd4v0	87	15	nephritis	nephritis	NN
cord-017161-lcqrd4v0	87	16	that	that	WDT
cord-017161-lcqrd4v0	87	17	is	be	VBZ
cord-017161-lcqrd4v0	87	18	not	not	RB
cord-017161-lcqrd4v0	87	19	rapidly	rapidly	RB
cord-017161-lcqrd4v0	87	20	progressive	progressive	JJ
cord-017161-lcqrd4v0	87	21	(	(	-LRB-
cord-017161-lcqrd4v0	87	22	patients	patient	NNS
cord-017161-lcqrd4v0	87	23	may	may	MD
cord-017161-lcqrd4v0	87	24	exhibit	exhibit	VB
cord-017161-lcqrd4v0	87	25	less	less	JJR
cord-017161-lcqrd4v0	87	26	than	than	IN
cord-017161-lcqrd4v0	87	27	50	50	CD
cord-017161-lcqrd4v0	87	28	%	%	NN
cord-017161-lcqrd4v0	87	29	crescents	crescent	NNS
cord-017161-lcqrd4v0	87	30	on	on	IN
cord-017161-lcqrd4v0	87	31	renal	renal	JJ
cord-017161-lcqrd4v0	87	32	biopsy	biopsy	NN
cord-017161-lcqrd4v0	87	33	,	,	,
cord-017161-lcqrd4v0	87	34	sub	sub	NN
cord-017161-lcqrd4v0	87	35	-	-	JJ
cord-017161-lcqrd4v0	87	36	optimal	optimal	JJ
cord-017161-lcqrd4v0	87	37	GFR	gfr	NN
cord-017161-lcqrd4v0	87	38	;	;	:
cord-017161-lcqrd4v0	87	39	heavy	heavy	JJ
cord-017161-lcqrd4v0	87	40	proteinuria	proteinuria	NN
cord-017161-lcqrd4v0	87	41	which	which	WDT
cord-017161-lcqrd4v0	87	42	is	be	VBZ
cord-017161-lcqrd4v0	87	43	not	not	RB
cord-017161-lcqrd4v0	87	44	necessarily	necessarily	RB
cord-017161-lcqrd4v0	87	45	nephrotic	nephrotic	JJ
cord-017161-lcqrd4v0	87	46	range	range	NN
cord-017161-lcqrd4v0	87	47	)	)	-RRB-
cord-017161-lcqrd4v0	88	1	[	[	-LRB-
cord-017161-lcqrd4v0	88	2	34	34	CD
cord-017161-lcqrd4v0	88	3	]	]	-RRB-
cord-017161-lcqrd4v0	88	4	.	.	.
cord-017161-lcqrd4v0	89	1	Many	many	JJ
cord-017161-lcqrd4v0	89	2	would	would	MD
cord-017161-lcqrd4v0	89	3	advocate	advocate	VB
cord-017161-lcqrd4v0	89	4	corticosteroids	corticosteroid	NNS
cord-017161-lcqrd4v0	89	5	[	[	-LRB-
cord-017161-lcqrd4v0	89	6	34	34	CD
cord-017161-lcqrd4v0	89	7	]	]	-RRB-
cord-017161-lcqrd4v0	89	8	.	.	.
cord-017161-lcqrd4v0	90	1	Others	other	NNS
cord-017161-lcqrd4v0	90	2	advocate	advocate	VBP
cord-017161-lcqrd4v0	90	3	the	the	DT
cord-017161-lcqrd4v0	90	4	addition	addition	NN
cord-017161-lcqrd4v0	90	5	of	of	IN
cord-017161-lcqrd4v0	90	6	cyclophosphamide	cyclophosphamide	NN
cord-017161-lcqrd4v0	90	7	to	to	IN
cord-017161-lcqrd4v0	90	8	corticosteroids	corticosteroid	NNS
cord-017161-lcqrd4v0	90	9	in	in	IN
cord-017161-lcqrd4v0	90	10	HSP	HSP	NNP
cord-017161-lcqrd4v0	90	11	nephritis	nephritis	NN
cord-017161-lcqrd4v0	90	12	with	with	IN
cord-017161-lcqrd4v0	90	13	biopsy	biopsy	NN
cord-017161-lcqrd4v0	90	14	showing	show	VBG
cord-017161-lcqrd4v0	90	15	diffuse	diffuse	JJ
cord-017161-lcqrd4v0	90	16	proliferative	proliferative	JJ
cord-017161-lcqrd4v0	90	17	lesions	lesion	NNS
cord-017161-lcqrd4v0	90	18	or	or	CC
cord-017161-lcqrd4v0	90	19	sclerosis	sclerosis	NN
cord-017161-lcqrd4v0	90	20	,	,	,
cord-017161-lcqrd4v0	90	21	but	but	CC
cord-017161-lcqrd4v0	90	22	with	with	IN
cord-017161-lcqrd4v0	90	23	<	<	XX
cord-017161-lcqrd4v0	90	24	50	50	CD
cord-017161-lcqrd4v0	90	25	%	%	NN
cord-017161-lcqrd4v0	90	26	crescentic	crescentic	JJ
cord-017161-lcqrd4v0	90	27	change	change	NN
cord-017161-lcqrd4v0	90	28	with	with	IN
cord-017161-lcqrd4v0	90	29	ongoing	ongoing	JJ
cord-017161-lcqrd4v0	90	30	heavy	heavy	JJ
cord-017161-lcqrd4v0	90	31	proteinuria	proteinuria	NN
cord-017161-lcqrd4v0	90	32	[	[	-LRB-
cord-017161-lcqrd4v0	90	33	34	34	CD
cord-017161-lcqrd4v0	90	34	]	]	-RRB-
cord-017161-lcqrd4v0	90	35	.	.	.
cord-017161-lcqrd4v0	91	1	In	in	IN
cord-017161-lcqrd4v0	91	2	patients	patient	NNS
cord-017161-lcqrd4v0	91	3	with	with	IN
cord-017161-lcqrd4v0	91	4	greater	great	JJR
cord-017161-lcqrd4v0	91	5	than	than	IN
cord-017161-lcqrd4v0	91	6	6	6	CD
cord-017161-lcqrd4v0	91	7	months	month	NNS
cord-017161-lcqrd4v0	91	8	duration	duration	NN
cord-017161-lcqrd4v0	91	9	of	of	IN
cord-017161-lcqrd4v0	91	10	proteinuria	proteinuria	NN
cord-017161-lcqrd4v0	91	11	,	,	,
cord-017161-lcqrd4v0	91	12	an	an	DT
cord-017161-lcqrd4v0	91	13	ACE	ace	NN
cord-017161-lcqrd4v0	91	14	inhibitor	inhibitor	NN
cord-017161-lcqrd4v0	91	15	may	may	MD
cord-017161-lcqrd4v0	91	16	be	be	VB
cord-017161-lcqrd4v0	91	17	indicated	indicate	VBN
cord-017161-lcqrd4v0	91	18	to	to	TO
cord-017161-lcqrd4v0	91	19	limit	limit	VB
cord-017161-lcqrd4v0	91	20	secondary	secondary	JJ
cord-017161-lcqrd4v0	91	21	glomerular	glomerular	JJ
cord-017161-lcqrd4v0	91	22	injury	injury	NN
cord-017161-lcqrd4v0	91	23	,	,	,
cord-017161-lcqrd4v0	91	24	although	although	IN
cord-017161-lcqrd4v0	91	25	again	again	RB
cord-017161-lcqrd4v0	91	26	the	the	DT
cord-017161-lcqrd4v0	91	27	evidence	evidence	NN
cord-017161-lcqrd4v0	91	28	to	to	TO
cord-017161-lcqrd4v0	91	29	support	support	VB
cord-017161-lcqrd4v0	91	30	this	this	DT
cord-017161-lcqrd4v0	91	31	therapy	therapy	NN
cord-017161-lcqrd4v0	91	32	is	be	VBZ
cord-017161-lcqrd4v0	91	33	lacking	lack	VBG
cord-017161-lcqrd4v0	91	34	.	.	.
cord-017161-lcqrd4v0	92	1	The	the	DT
cord-017161-lcqrd4v0	92	2	majority	majority	NN
cord-017161-lcqrd4v0	92	3	of	of	IN
cord-017161-lcqrd4v0	92	4	children	child	NNS
cord-017161-lcqrd4v0	92	5	with	with	IN
cord-017161-lcqrd4v0	92	6	HSP	HSP	NNP
cord-017161-lcqrd4v0	92	7	make	make	VBP
cord-017161-lcqrd4v0	92	8	a	a	DT
cord-017161-lcqrd4v0	92	9	full	full	JJ
cord-017161-lcqrd4v0	92	10	and	and	CC
cord-017161-lcqrd4v0	92	11	uneventful	uneventful	JJ
cord-017161-lcqrd4v0	92	12	recovery	recovery	NN
cord-017161-lcqrd4v0	92	13	with	with	IN
cord-017161-lcqrd4v0	92	14	no	no	DT
cord-017161-lcqrd4v0	92	15	evidence	evidence	NN
cord-017161-lcqrd4v0	92	16	of	of	IN
cord-017161-lcqrd4v0	92	17	ongoing	ongoing	JJ
cord-017161-lcqrd4v0	92	18	signi	signi	NNP
cord-017161-lcqrd4v0	92	19	fi	fi	NN
cord-017161-lcqrd4v0	93	1	ca	can	MD
cord-017161-lcqrd4v0	93	2	nt	not	RB
cord-017161-lcqrd4v0	93	3	renal	renal	JJ
cord-017161-lcqrd4v0	93	4	disease	disease	NN
cord-017161-lcqrd4v0	93	5	[	[	-LRB-
cord-017161-lcqrd4v0	93	6	34	34	CD
cord-017161-lcqrd4v0	93	7	]	]	-RRB-
cord-017161-lcqrd4v0	93	8	.	.	.
cord-017161-lcqrd4v0	94	1	Renal	renal	JJ
cord-017161-lcqrd4v0	94	2	involvement	involvement	NN
cord-017161-lcqrd4v0	94	3	is	be	VBZ
cord-017161-lcqrd4v0	94	4	the	the	DT
cord-017161-lcqrd4v0	94	5	most	most	RBS
cord-017161-lcqrd4v0	94	6	serious	serious	JJ
cord-017161-lcqrd4v0	94	7	long	long	JJ
cord-017161-lcqrd4v0	94	8	-	-	HYPH
cord-017161-lcqrd4v0	94	9	term	term	NN
cord-017161-lcqrd4v0	94	10	complication	complication	NN
cord-017161-lcqrd4v0	94	11	of	of	IN
cord-017161-lcqrd4v0	94	12	HSP	HSP	NNP
cord-017161-lcqrd4v0	94	13	[	[	-LRB-
cord-017161-lcqrd4v0	94	14	34	34	CD
cord-017161-lcqrd4v0	94	15	]	]	-RRB-
cord-017161-lcqrd4v0	94	16	.	.	.
cord-017161-lcqrd4v0	95	1	Narchi	Narchi	NNP
cord-017161-lcqrd4v0	95	2	et	et	NNP
cord-017161-lcqrd4v0	95	3	al	al	NNP
cord-017161-lcqrd4v0	95	4	.	.	.
cord-017161-lcqrd4v0	96	1	systematically	systematically	RB
cord-017161-lcqrd4v0	96	2	reviewed	review	VBD
cord-017161-lcqrd4v0	96	3	all	all	DT
cord-017161-lcqrd4v0	96	4	published	publish	VBN
cord-017161-lcqrd4v0	96	5	literature	literature	NN
cord-017161-lcqrd4v0	96	6	with	with	IN
cord-017161-lcqrd4v0	96	7	regards	regard	NNS
cord-017161-lcqrd4v0	96	8	to	to	IN
cord-017161-lcqrd4v0	96	9	long	long	JJ
cord-017161-lcqrd4v0	96	10	-	-	HYPH
cord-017161-lcqrd4v0	96	11	term	term	NN
cord-017161-lcqrd4v0	96	12	renal	renal	JJ
cord-017161-lcqrd4v0	96	13	impairment	impairment	NN
cord-017161-lcqrd4v0	96	14	in	in	IN
cord-017161-lcqrd4v0	96	15	children	child	NNS
cord-017161-lcqrd4v0	96	16	with	with	IN
cord-017161-lcqrd4v0	96	17	HSP	HSP	NNP
cord-017161-lcqrd4v0	96	18	[	[	-LRB-
cord-017161-lcqrd4v0	96	19	44	44	CD
cord-017161-lcqrd4v0	96	20	]	]	-RRB-
cord-017161-lcqrd4v0	96	21	.	.	.
cord-017161-lcqrd4v0	97	1	Persistent	persistent	JJ
cord-017161-lcqrd4v0	97	2	renal	renal	JJ
cord-017161-lcqrd4v0	97	3	involvement	involvement	NN
cord-017161-lcqrd4v0	97	4	(	(	-LRB-
cord-017161-lcqrd4v0	97	5	hypertension	hypertension	NN
cord-017161-lcqrd4v0	97	6	,	,	,
cord-017161-lcqrd4v0	97	7	reduced	reduce	VBN
cord-017161-lcqrd4v0	97	8	renal	renal	JJ
cord-017161-lcqrd4v0	97	9	function	function	NN
cord-017161-lcqrd4v0	97	10	,	,	,
cord-017161-lcqrd4v0	97	11	nephrotic	nephrotic	JJ
cord-017161-lcqrd4v0	97	12	or	or	CC
cord-017161-lcqrd4v0	97	13	nephritic	nephritic	JJ
cord-017161-lcqrd4v0	97	14	syndrome	syndrome	NN
cord-017161-lcqrd4v0	97	15	)	)	-RRB-
cord-017161-lcqrd4v0	97	16	occurred	occur	VBD
cord-017161-lcqrd4v0	97	17	in	in	IN
cord-017161-lcqrd4v0	97	18	1.8	1.8	CD
cord-017161-lcqrd4v0	97	19	%	%	NN
cord-017161-lcqrd4v0	97	20	of	of	IN
cord-017161-lcqrd4v0	97	21	children	child	NNS
cord-017161-lcqrd4v0	97	22	overall	overall	RB
cord-017161-lcqrd4v0	97	23	,	,	,
cord-017161-lcqrd4v0	97	24	but	but	CC
cord-017161-lcqrd4v0	97	25	the	the	DT
cord-017161-lcqrd4v0	97	26	incidence	incidence	NN
cord-017161-lcqrd4v0	97	27	varied	vary	VBN
cord-017161-lcqrd4v0	97	28	with	with	IN
cord-017161-lcqrd4v0	97	29	the	the	DT
cord-017161-lcqrd4v0	97	30	severity	severity	NN
cord-017161-lcqrd4v0	97	31	of	of	IN
cord-017161-lcqrd4v0	97	32	the	the	DT
cord-017161-lcqrd4v0	97	33	kidney	kidney	NN
cord-017161-lcqrd4v0	97	34	disease	disease	NN
cord-017161-lcqrd4v0	97	35	at	at	IN
cord-017161-lcqrd4v0	97	36	presentation	presentation	NN
cord-017161-lcqrd4v0	97	37	,	,	,
cord-017161-lcqrd4v0	97	38	occurring	occur	VBG
cord-017161-lcqrd4v0	97	39	in	in	IN
cord-017161-lcqrd4v0	97	40	5	5	CD
cord-017161-lcqrd4v0	97	41	%	%	NN
cord-017161-lcqrd4v0	97	42	of	of	IN
cord-017161-lcqrd4v0	97	43	children	child	NNS
cord-017161-lcqrd4v0	97	44	with	with	IN
cord-017161-lcqrd4v0	97	45	isolated	isolate	VBN
cord-017161-lcqrd4v0	97	46	haematuria	haematuria	NNS
cord-017161-lcqrd4v0	97	47	and/or	and/or	CC
cord-017161-lcqrd4v0	97	48	proteinuria	proteinuria	NN
cord-017161-lcqrd4v0	97	49	but	but	CC
cord-017161-lcqrd4v0	97	50	in	in	IN
cord-017161-lcqrd4v0	97	51	20	20	CD
cord-017161-lcqrd4v0	97	52	%	%	NN
cord-017161-lcqrd4v0	97	53	who	who	WP
cord-017161-lcqrd4v0	97	54	had	have	VBD
cord-017161-lcqrd4v0	97	55	acute	acute	JJ
cord-017161-lcqrd4v0	97	56	nephritis	nephritis	NN
cord-017161-lcqrd4v0	97	57	and/or	and/or	CC
cord-017161-lcqrd4v0	97	58	nephrotic	nephrotic	JJ
cord-017161-lcqrd4v0	97	59	syndrome	syndrome	NN
cord-017161-lcqrd4v0	97	60	in	in	IN
cord-017161-lcqrd4v0	97	61	the	the	DT
cord-017161-lcqrd4v0	97	62	acute	acute	JJ
cord-017161-lcqrd4v0	97	63	phase	phase	NN
cord-017161-lcqrd4v0	97	64	[	[	-LRB-
cord-017161-lcqrd4v0	97	65	44	44	CD
cord-017161-lcqrd4v0	97	66	]	]	-RRB-
cord-017161-lcqrd4v0	97	67	.	.	.
cord-017161-lcqrd4v0	98	1	KD	KD	NNP
cord-017161-lcqrd4v0	98	2	is	be	VBZ
cord-017161-lcqrd4v0	98	3	an	an	DT
cord-017161-lcqrd4v0	98	4	acute	acute	JJ
cord-017161-lcqrd4v0	98	5	self	self	NN
cord-017161-lcqrd4v0	98	6	-	-	HYPH
cord-017161-lcqrd4v0	98	7	limiting	limit	VBG
cord-017161-lcqrd4v0	98	8	systemic	systemic	JJ
cord-017161-lcqrd4v0	98	9	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	98	10	predominantly	predominantly	RB
cord-017161-lcqrd4v0	98	11	affecting	affect	VBG
cord-017161-lcqrd4v0	98	12	young	young	JJ
cord-017161-lcqrd4v0	98	13	children	child	NNS
cord-017161-lcqrd4v0	98	14	[	[	-LRB-
cord-017161-lcqrd4v0	98	15	2	2	CD
cord-017161-lcqrd4v0	98	16	]	]	-RRB-
cord-017161-lcqrd4v0	98	17	.	.	.
cord-017161-lcqrd4v0	99	1	It	-PRON-	PRP
cord-017161-lcqrd4v0	99	2	is	be	VBZ
cord-017161-lcqrd4v0	99	3	distributed	distribute	VBN
cord-017161-lcqrd4v0	99	4	worldwide	worldwide	RB
cord-017161-lcqrd4v0	99	5	,	,	,
cord-017161-lcqrd4v0	99	6	with	with	IN
cord-017161-lcqrd4v0	99	7	a	a	DT
cord-017161-lcqrd4v0	99	8	male	male	JJ
cord-017161-lcqrd4v0	99	9	preponderance	preponderance	NN
cord-017161-lcqrd4v0	99	10	,	,	,
cord-017161-lcqrd4v0	99	11	an	an	DT
cord-017161-lcqrd4v0	99	12	ethnic	ethnic	JJ
cord-017161-lcqrd4v0	99	13	bias	bias	NN
cord-017161-lcqrd4v0	99	14	towards	towards	IN
cord-017161-lcqrd4v0	99	15	Asian	asian	JJ
cord-017161-lcqrd4v0	99	16	children	child	NNS
cord-017161-lcqrd4v0	99	17	,	,	,
cord-017161-lcqrd4v0	99	18	some	some	DT
cord-017161-lcqrd4v0	99	19	seasonality	seasonality	NN
cord-017161-lcqrd4v0	99	20	and	and	CC
cord-017161-lcqrd4v0	99	21	occasional	occasional	JJ
cord-017161-lcqrd4v0	99	22	epidemics	epidemic	NNS
cord-017161-lcqrd4v0	99	23	[	[	-LRB-
cord-017161-lcqrd4v0	99	24	45	45	CD
cord-017161-lcqrd4v0	99	25	]	]	-RRB-
cord-017161-lcqrd4v0	99	26	[	[	-LRB-
cord-017161-lcqrd4v0	99	27	46	46	CD
cord-017161-lcqrd4v0	99	28	]	]	-RRB-
cord-017161-lcqrd4v0	99	29	[	[	-LRB-
cord-017161-lcqrd4v0	99	30	47	47	CD
cord-017161-lcqrd4v0	99	31	]	]	-RRB-
cord-017161-lcqrd4v0	99	32	[	[	-LRB-
cord-017161-lcqrd4v0	99	33	48	48	CD
cord-017161-lcqrd4v0	99	34	]	]	-RRB-
cord-017161-lcqrd4v0	99	35	[	[	-LRB-
cord-017161-lcqrd4v0	99	36	49	49	CD
cord-017161-lcqrd4v0	99	37	]	]	-RRB-
cord-017161-lcqrd4v0	99	38	.	.	.
cord-017161-lcqrd4v0	100	1	It	-PRON-	PRP
cord-017161-lcqrd4v0	100	2	is	be	VBZ
cord-017161-lcqrd4v0	100	3	the	the	DT
cord-017161-lcqrd4v0	100	4	second	second	JJ
cord-017161-lcqrd4v0	100	5	most	most	RBS
cord-017161-lcqrd4v0	100	6	common	common	JJ
cord-017161-lcqrd4v0	100	7	vasculitic	vasculitic	JJ
cord-017161-lcqrd4v0	100	8	illness	illness	NN
cord-017161-lcqrd4v0	100	9	of	of	IN
cord-017161-lcqrd4v0	100	10	childhood	childhood	NN
cord-017161-lcqrd4v0	100	11	and	and	CC
cord-017161-lcqrd4v0	100	12	the	the	DT
cord-017161-lcqrd4v0	100	13	most	most	RBS
cord-017161-lcqrd4v0	100	14	common	common	JJ
cord-017161-lcqrd4v0	100	15	cause	cause	NN
cord-017161-lcqrd4v0	100	16	of	of	IN
cord-017161-lcqrd4v0	100	17	acquired	acquire	VBN
cord-017161-lcqrd4v0	100	18	heart	heart	NN
cord-017161-lcqrd4v0	100	19	disease	disease	NN
cord-017161-lcqrd4v0	100	20	in	in	IN
cord-017161-lcqrd4v0	100	21	children	child	NNS
cord-017161-lcqrd4v0	100	22	in	in	IN
cord-017161-lcqrd4v0	100	23	the	the	DT
cord-017161-lcqrd4v0	100	24	UK	UK	NNP
cord-017161-lcqrd4v0	100	25	and	and	CC
cord-017161-lcqrd4v0	100	26	the	the	DT
cord-017161-lcqrd4v0	100	27	USA	USA	NNP
cord-017161-lcqrd4v0	100	28	[	[	-LRB-
cord-017161-lcqrd4v0	100	29	2	2	CD
cord-017161-lcqrd4v0	100	30	,	,	,
cord-017161-lcqrd4v0	100	31	50	50	CD
cord-017161-lcqrd4v0	100	32	,	,	,
cord-017161-lcqrd4v0	100	33	51	51	CD
cord-017161-lcqrd4v0	100	34	]	]	-RRB-
cord-017161-lcqrd4v0	100	35	.	.	.
cord-017161-lcqrd4v0	101	1	The	the	DT
cord-017161-lcqrd4v0	101	2	incidence	incidence	NN
cord-017161-lcqrd4v0	101	3	in	in	IN
cord-017161-lcqrd4v0	101	4	Japan	Japan	NNP
cord-017161-lcqrd4v0	101	5	is	be	VBZ
cord-017161-lcqrd4v0	101	6	138/100,000	138/100,000	CD
cord-017161-lcqrd4v0	101	7	[	[	-LRB-
cord-017161-lcqrd4v0	101	8	52	52	CD
cord-017161-lcqrd4v0	101	9	]	]	-RRB-
cord-017161-lcqrd4v0	101	10	in	in	IN
cord-017161-lcqrd4v0	101	11	children	child	NNS
cord-017161-lcqrd4v0	101	12	younger	young	JJR
cord-017161-lcqrd4v0	101	13	than	than	IN
cord-017161-lcqrd4v0	101	14	5	5	CD
cord-017161-lcqrd4v0	101	15	years	year	NNS
cord-017161-lcqrd4v0	101	16	,	,	,
cord-017161-lcqrd4v0	101	17	whereas	whereas	IN
cord-017161-lcqrd4v0	101	18	in	in	IN
cord-017161-lcqrd4v0	101	19	the	the	DT
cord-017161-lcqrd4v0	101	20	USA	USA	NNP
cord-017161-lcqrd4v0	101	21	it	-PRON-	PRP
cord-017161-lcqrd4v0	101	22	is	be	VBZ
cord-017161-lcqrd4v0	101	23	17.1	17.1	CD
cord-017161-lcqrd4v0	101	24	[	[	-LRB-
cord-017161-lcqrd4v0	101	25	53	53	CD
cord-017161-lcqrd4v0	101	26	]	]	-RRB-
cord-017161-lcqrd4v0	101	27	and	and	CC
cord-017161-lcqrd4v0	101	28	in	in	IN
cord-017161-lcqrd4v0	101	29	the	the	DT
cord-017161-lcqrd4v0	101	30	UK	UK	NNP
cord-017161-lcqrd4v0	101	31	8.1	8.1	CD
cord-017161-lcqrd4v0	101	32	[	[	-LRB-
cord-017161-lcqrd4v0	101	33	54	54	CD
cord-017161-lcqrd4v0	101	34	]	]	-RRB-
cord-017161-lcqrd4v0	101	35	.	.	.
cord-017161-lcqrd4v0	102	1	The	the	DT
cord-017161-lcqrd4v0	102	2	aetiology	aetiology	NN
cord-017161-lcqrd4v0	102	3	of	of	IN
cord-017161-lcqrd4v0	102	4	KD	KD	NNP
cord-017161-lcqrd4v0	102	5	remains	remain	VBZ
cord-017161-lcqrd4v0	102	6	unknown	unknown	JJ
cord-017161-lcqrd4v0	102	7	,	,	,
cord-017161-lcqrd4v0	102	8	but	but	CC
cord-017161-lcqrd4v0	102	9	currently	currently	RB
cord-017161-lcqrd4v0	102	10	it	-PRON-	PRP
cord-017161-lcqrd4v0	102	11	is	be	VBZ
cord-017161-lcqrd4v0	102	12	felt	feel	VBN
cord-017161-lcqrd4v0	102	13	that	that	IN
cord-017161-lcqrd4v0	102	14	some	some	DT
cord-017161-lcqrd4v0	102	15	ubiquitous	ubiquitous	JJ
cord-017161-lcqrd4v0	102	16	infectious	infectious	JJ
cord-017161-lcqrd4v0	102	17	agent	agent	NN
cord-017161-lcqrd4v0	102	18	produces	produce	VBZ
cord-017161-lcqrd4v0	102	19	an	an	DT
cord-017161-lcqrd4v0	102	20	abnormal	abnormal	JJ
cord-017161-lcqrd4v0	102	21	immunological	immunological	JJ
cord-017161-lcqrd4v0	102	22	response	response	NN
cord-017161-lcqrd4v0	102	23	in	in	IN
cord-017161-lcqrd4v0	102	24	a	a	DT
cord-017161-lcqrd4v0	102	25	genetically	genetically	RB
cord-017161-lcqrd4v0	102	26	susceptible	susceptible	JJ
cord-017161-lcqrd4v0	102	27	subject	subject	NN
cord-017161-lcqrd4v0	102	28	that	that	WDT
cord-017161-lcqrd4v0	102	29	results	result	VBZ
cord-017161-lcqrd4v0	102	30	in	in	IN
cord-017161-lcqrd4v0	102	31	the	the	DT
cord-017161-lcqrd4v0	102	32	characteristic	characteristic	JJ
cord-017161-lcqrd4v0	102	33	clinical	clinical	JJ
cord-017161-lcqrd4v0	102	34	picture	picture	NN
cord-017161-lcqrd4v0	102	35	[	[	-LRB-
cord-017161-lcqrd4v0	102	36	55	55	CD
cord-017161-lcqrd4v0	102	37	,	,	,
cord-017161-lcqrd4v0	102	38	56	56	CD
cord-017161-lcqrd4v0	102	39	]	]	-RRB-
cord-017161-lcqrd4v0	102	40	.	.	.
cord-017161-lcqrd4v0	103	1	Pronounced	pronounce	VBN
cord-017161-lcqrd4v0	103	2	seasonality	seasonality	NN
cord-017161-lcqrd4v0	103	3	and	and	CC
cord-017161-lcqrd4v0	103	4	clustering	clustering	NN
cord-017161-lcqrd4v0	103	5	of	of	IN
cord-017161-lcqrd4v0	103	6	KD	KD	NNP
cord-017161-lcqrd4v0	103	7	cases	case	NNS
cord-017161-lcqrd4v0	103	8	have	have	VBP
cord-017161-lcqrd4v0	103	9	led	lead	VBN
cord-017161-lcqrd4v0	103	10	to	to	IN
cord-017161-lcqrd4v0	103	11	the	the	DT
cord-017161-lcqrd4v0	103	12	hunt	hunt	NN
cord-017161-lcqrd4v0	103	13	for	for	IN
cord-017161-lcqrd4v0	103	14	infectious	infectious	JJ
cord-017161-lcqrd4v0	103	15	agents	agent	NNS
cord-017161-lcqrd4v0	103	16	as	as	IN
cord-017161-lcqrd4v0	103	17	a	a	DT
cord-017161-lcqrd4v0	103	18	cause	cause	NN
cord-017161-lcqrd4v0	103	19	[	[	-LRB-
cord-017161-lcqrd4v0	103	20	55	55	CD
cord-017161-lcqrd4v0	103	21	,	,	,
cord-017161-lcqrd4v0	103	22	56	56	CD
cord-017161-lcqrd4v0	103	23	]	]	-RRB-
cord-017161-lcqrd4v0	103	24	.	.	.
cord-017161-lcqrd4v0	104	1	However	however	RB
cord-017161-lcqrd4v0	104	2	,	,	,
cord-017161-lcqrd4v0	104	3	so	so	RB
cord-017161-lcqrd4v0	104	4	far	far	RB
cord-017161-lcqrd4v0	104	5	no	no	DT
cord-017161-lcqrd4v0	104	6	single	single	JJ
cord-017161-lcqrd4v0	104	7	agent	agent	NN
cord-017161-lcqrd4v0	104	8	has	have	VBZ
cord-017161-lcqrd4v0	104	9	been	be	VBN
cord-017161-lcqrd4v0	104	10	identi	identi	FW
cord-017161-lcqrd4v0	104	11	fi	fi	NNP
cord-017161-lcqrd4v0	104	12	ed	ed	NNP
cord-017161-lcqrd4v0	104	13	,	,	,
cord-017161-lcqrd4v0	104	14	a	a	DT
cord-017161-lcqrd4v0	104	15	fact	fact	NN
cord-017161-lcqrd4v0	104	16	most	most	RBS
cord-017161-lcqrd4v0	104	17	recently	recently	RB
cord-017161-lcqrd4v0	104	18	highlighted	highlight	VBN
cord-017161-lcqrd4v0	104	19	by	by	IN
cord-017161-lcqrd4v0	104	20	the	the	DT
cord-017161-lcqrd4v0	104	21	negative	negative	JJ
cord-017161-lcqrd4v0	104	22	results	result	NNS
cord-017161-lcqrd4v0	104	23	that	that	WDT
cord-017161-lcqrd4v0	104	24	emerged	emerge	VBD
cord-017161-lcqrd4v0	104	25	from	from	IN
cord-017161-lcqrd4v0	104	26	studies	study	NNS
cord-017161-lcqrd4v0	104	27	examining	examine	VBG
cord-017161-lcqrd4v0	104	28	the	the	DT
cord-017161-lcqrd4v0	104	29	potential	potential	JJ
cord-017161-lcqrd4v0	104	30	link	link	NN
cord-017161-lcqrd4v0	104	31	between	between	IN
cord-017161-lcqrd4v0	104	32	coronavirus	coronavirus	NN
cord-017161-lcqrd4v0	104	33	infection	infection	NN
cord-017161-lcqrd4v0	104	34	and	and	CC
cord-017161-lcqrd4v0	104	35	KD	KD	NNP
cord-017161-lcqrd4v0	104	36	in	in	IN
cord-017161-lcqrd4v0	104	37	Taiwan	Taiwan	NNP
cord-017161-lcqrd4v0	104	38	[	[	-LRB-
cord-017161-lcqrd4v0	104	39	57	57	CD
cord-017161-lcqrd4v0	104	40	]	]	-RRB-
cord-017161-lcqrd4v0	104	41	.	.	.
cord-017161-lcqrd4v0	105	1	One	one	CD
cord-017161-lcqrd4v0	105	2	debate	debate	NN
cord-017161-lcqrd4v0	105	3	regarding	regard	VBG
cord-017161-lcqrd4v0	105	4	the	the	DT
cord-017161-lcqrd4v0	105	5	cause	cause	NN
cord-017161-lcqrd4v0	105	6	of	of	IN
cord-017161-lcqrd4v0	105	7	KD	KD	NNP
cord-017161-lcqrd4v0	105	8	has	have	VBZ
cord-017161-lcqrd4v0	105	9	centred	centre	VBN
cord-017161-lcqrd4v0	105	10	around	around	IN
cord-017161-lcqrd4v0	105	11	the	the	DT
cord-017161-lcqrd4v0	105	12	mechanism	mechanism	NN
cord-017161-lcqrd4v0	105	13	of	of	IN
cord-017161-lcqrd4v0	105	14	immune	immune	JJ
cord-017161-lcqrd4v0	105	15	activation	activation	NN
cord-017161-lcqrd4v0	105	16	:	:	:
cord-017161-lcqrd4v0	105	17	conventional	conventional	JJ
cord-017161-lcqrd4v0	105	18	antigen	antigen	NN
cord-017161-lcqrd4v0	105	19	versus	versus	IN
cord-017161-lcqrd4v0	105	20	superantigen	superantigen	NNP
cord-017161-lcqrd4v0	105	21	(	(	-LRB-
cord-017161-lcqrd4v0	105	22	SAg	SAg	NNS
cord-017161-lcqrd4v0	105	23	)	)	-RRB-
cord-017161-lcqrd4v0	105	24	[	[	-LRB-
cord-017161-lcqrd4v0	106	1	55	55	CD
cord-017161-lcqrd4v0	106	2	,	,	,
cord-017161-lcqrd4v0	106	3	58	58	CD
cord-017161-lcqrd4v0	106	4	]	]	-RRB-
cord-017161-lcqrd4v0	106	5	.	.	.
cord-017161-lcqrd4v0	107	1	SAgs	SAgs	NNP
cord-017161-lcqrd4v0	107	2	are	be	VBP
cord-017161-lcqrd4v0	107	3	a	a	DT
cord-017161-lcqrd4v0	107	4	group	group	NN
cord-017161-lcqrd4v0	107	5	of	of	IN
cord-017161-lcqrd4v0	107	6	proteins	protein	NNS
cord-017161-lcqrd4v0	107	7	that	that	WDT
cord-017161-lcqrd4v0	107	8	share	share	VBP
cord-017161-lcqrd4v0	107	9	the	the	DT
cord-017161-lcqrd4v0	107	10	ability	ability	NN
cord-017161-lcqrd4v0	107	11	to	to	TO
cord-017161-lcqrd4v0	107	12	stimulate	stimulate	VB
cord-017161-lcqrd4v0	107	13	a	a	DT
cord-017161-lcqrd4v0	107	14	large	large	JJ
cord-017161-lcqrd4v0	107	15	proportion	proportion	NN
cord-017161-lcqrd4v0	107	16	of	of	IN
cord-017161-lcqrd4v0	107	17	T	t	NN
cord-017161-lcqrd4v0	107	18	cells	cell	NNS
cord-017161-lcqrd4v0	107	19	(	(	-LRB-
cord-017161-lcqrd4v0	107	20	up	up	IN
cord-017161-lcqrd4v0	107	21	to	to	TO
cord-017161-lcqrd4v0	107	22	30	30	CD
cord-017161-lcqrd4v0	107	23	%	%	NN
cord-017161-lcqrd4v0	107	24	of	of	IN
cord-017161-lcqrd4v0	107	25	the	the	DT
cord-017161-lcqrd4v0	107	26	T	t	NN
cord-017161-lcqrd4v0	107	27	-	-	HYPH
cord-017161-lcqrd4v0	107	28	cell	cell	NN
cord-017161-lcqrd4v0	107	29	repertoire	repertoire	NN
cord-017161-lcqrd4v0	107	30	compared	compare	VBN
cord-017161-lcqrd4v0	107	31	with	with	IN
cord-017161-lcqrd4v0	107	32	one	one	CD
cord-017161-lcqrd4v0	107	33	in	in	IN
cord-017161-lcqrd4v0	107	34	a	a	DT
cord-017161-lcqrd4v0	107	35	million	million	CD
cord-017161-lcqrd4v0	107	36	T	t	NN
cord-017161-lcqrd4v0	107	37	cells	cell	NNS
cord-017161-lcqrd4v0	107	38	for	for	IN
cord-017161-lcqrd4v0	107	39	conventional	conventional	JJ
cord-017161-lcqrd4v0	107	40	antigens	antigen	NNS
cord-017161-lcqrd4v0	107	41	)	)	-RRB-
cord-017161-lcqrd4v0	107	42	by	by	IN
cord-017161-lcqrd4v0	107	43	binding	bind	VBG
cord-017161-lcqrd4v0	107	44	to	to	IN
cord-017161-lcqrd4v0	107	45	a	a	DT
cord-017161-lcqrd4v0	107	46	portion	portion	NN
cord-017161-lcqrd4v0	107	47	of	of	IN
cord-017161-lcqrd4v0	107	48	the	the	DT
cord-017161-lcqrd4v0	107	49	T	t	NN
cord-017161-lcqrd4v0	107	50	-	-	HYPH
cord-017161-lcqrd4v0	107	51	cell	cell	NN
cord-017161-lcqrd4v0	107	52	receptor	receptor	NN
cord-017161-lcqrd4v0	107	53	b	b	NN
cord-017161-lcqrd4v0	107	54	chain	chain	NN
cord-017161-lcqrd4v0	107	55	(	(	-LRB-
cord-017161-lcqrd4v0	107	56	TCRV	TCRV	NNP
cord-017161-lcqrd4v0	107	57	b	b	NNP
cord-017161-lcqrd4v0	107	58	)	)	-RRB-
cord-017161-lcqrd4v0	107	59	in	in	IN
cord-017161-lcqrd4v0	107	60	association	association	NN
cord-017161-lcqrd4v0	107	61	with	with	IN
cord-017161-lcqrd4v0	107	62	the	the	DT
cord-017161-lcqrd4v0	107	63	major	major	JJ
cord-017161-lcqrd4v0	107	64	histocompatibility	histocompatibility	NN
cord-017161-lcqrd4v0	107	65	complex	complex	NN
cord-017161-lcqrd4v0	107	66	(	(	-LRB-
cord-017161-lcqrd4v0	107	67	MHC	MHC	NNP
cord-017161-lcqrd4v0	107	68	)	)	-RRB-
cord-017161-lcqrd4v0	107	69	class	class	NN
cord-017161-lcqrd4v0	107	70	II	ii	CD
cord-017161-lcqrd4v0	107	71	molecules	molecule	NNS
cord-017161-lcqrd4v0	107	72	with	with	IN
cord-017161-lcqrd4v0	107	73	no	no	DT
cord-017161-lcqrd4v0	107	74	requirement	requirement	NN
cord-017161-lcqrd4v0	107	75	for	for	IN
cord-017161-lcqrd4v0	107	76	antigen	antigen	NN
cord-017161-lcqrd4v0	107	77	processing	processing	NN
cord-017161-lcqrd4v0	107	78	[	[	-LRB-
cord-017161-lcqrd4v0	107	79	59	59	CD
cord-017161-lcqrd4v0	107	80	]	]	-RRB-
cord-017161-lcqrd4v0	107	81	.	.	.
cord-017161-lcqrd4v0	108	1	SAgs	SAgs	NNP
cord-017161-lcqrd4v0	108	2	have	have	VBP
cord-017161-lcqrd4v0	108	3	been	be	VBN
cord-017161-lcqrd4v0	108	4	identi	identi	FW
cord-017161-lcqrd4v0	108	5	fi	fi	NNP
cord-017161-lcqrd4v0	108	6	ed	ed	NN
cord-017161-lcqrd4v0	108	7	in	in	IN
cord-017161-lcqrd4v0	108	8	a	a	DT
cord-017161-lcqrd4v0	108	9	variety	variety	NN
cord-017161-lcqrd4v0	108	10	of	of	IN
cord-017161-lcqrd4v0	108	11	microorganisms	microorganism	NNS
cord-017161-lcqrd4v0	108	12	,	,	,
cord-017161-lcqrd4v0	108	13	including	include	VBG
cord-017161-lcqrd4v0	108	14	many	many	JJ
cord-017161-lcqrd4v0	108	15	of	of	IN
cord-017161-lcqrd4v0	108	16	the	the	DT
cord-017161-lcqrd4v0	108	17	bacteria	bacteria	NNS
cord-017161-lcqrd4v0	108	18	and	and	CC
cord-017161-lcqrd4v0	108	19	viruses	virus	NNS
cord-017161-lcqrd4v0	108	20	isolated	isolate	VBN
cord-017161-lcqrd4v0	108	21	from	from	IN
cord-017161-lcqrd4v0	108	22	children	child	NNS
cord-017161-lcqrd4v0	108	23	with	with	IN
cord-017161-lcqrd4v0	108	24	KD	KD	NNP
cord-017161-lcqrd4v0	108	25	[	[	-LRB-
cord-017161-lcqrd4v0	108	26	55	55	CD
cord-017161-lcqrd4v0	108	27	,	,	,
cord-017161-lcqrd4v0	108	28	59	59	CD
cord-017161-lcqrd4v0	108	29	,	,	,
cord-017161-lcqrd4v0	108	30	60	60	CD
cord-017161-lcqrd4v0	108	31	]	]	-RRB-
cord-017161-lcqrd4v0	108	32	.	.	.
cord-017161-lcqrd4v0	109	1	In	in	IN
cord-017161-lcqrd4v0	109	2	1992	1992	CD
cord-017161-lcqrd4v0	109	3	,	,	,
cord-017161-lcqrd4v0	109	4	Abe	Abe	NNP
cord-017161-lcqrd4v0	109	5	et	et	NNP
cord-017161-lcqrd4v0	109	6	al	al	NNP
cord-017161-lcqrd4v0	109	7	.	.	NNP
cord-017161-lcqrd4v0	109	8	were	be	VBD
cord-017161-lcqrd4v0	109	9	the	the	DT
cord-017161-lcqrd4v0	109	10	fi	fi	NN
cord-017161-lcqrd4v0	109	11	rst	rst	NNP
cord-017161-lcqrd4v0	109	12	to	to	TO
cord-017161-lcqrd4v0	109	13	describe	describe	VB
cord-017161-lcqrd4v0	109	14	the	the	DT
cord-017161-lcqrd4v0	109	15	selective	selective	JJ
cord-017161-lcqrd4v0	109	16	expansion	expansion	NN
cord-017161-lcqrd4v0	109	17	of	of	IN
cord-017161-lcqrd4v0	109	18	V	v	NN
cord-017161-lcqrd4v0	109	19	b	b	NN
cord-017161-lcqrd4v0	109	20	2	2	CD
cord-017161-lcqrd4v0	109	21	and	and	CC
cord-017161-lcqrd4v0	109	22	V	v	NN
cord-017161-lcqrd4v0	109	23	b	b	NN
cord-017161-lcqrd4v0	109	24	8.1	8.1	CD
cord-017161-lcqrd4v0	109	25	T	t	NN
cord-017161-lcqrd4v0	109	26	cells	cell	NNS
cord-017161-lcqrd4v0	109	27	in	in	IN
cord-017161-lcqrd4v0	109	28	KD	KD	NNP
cord-017161-lcqrd4v0	109	29	[	[	-LRB-
cord-017161-lcqrd4v0	109	30	61	61	CD
cord-017161-lcqrd4v0	109	31	]	]	-RRB-
cord-017161-lcqrd4v0	109	32	,	,	,
cord-017161-lcqrd4v0	109	33	indicating	indicate	VBG
cord-017161-lcqrd4v0	109	34	T	t	NN
cord-017161-lcqrd4v0	109	35	-	-	HYPH
cord-017161-lcqrd4v0	109	36	cell	cell	NN
cord-017161-lcqrd4v0	109	37	V	v	NN
cord-017161-lcqrd4v0	109	38	b	b	NN
cord-017161-lcqrd4v0	109	39	skewingthe	skewingthe	NNP
cord-017161-lcqrd4v0	109	40	hallmark	hallmark	NN
cord-017161-lcqrd4v0	109	41	of	of	IN
cord-017161-lcqrd4v0	109	42	a	a	DT
cord-017161-lcqrd4v0	109	43	SAg	SAg	NNS
cord-017161-lcqrd4v0	109	44	-	-	HYPH
cord-017161-lcqrd4v0	109	45	mediated	mediate	VBN
cord-017161-lcqrd4v0	109	46	process	process	NN
cord-017161-lcqrd4v0	109	47	.	.	.
cord-017161-lcqrd4v0	110	1	Since	since	IN
cord-017161-lcqrd4v0	110	2	then	then	RB
cord-017161-lcqrd4v0	110	3	,	,	,
cord-017161-lcqrd4v0	110	4	many	many	JJ
cord-017161-lcqrd4v0	110	5	similar	similar	JJ
cord-017161-lcqrd4v0	110	6	studies	study	NNS
cord-017161-lcqrd4v0	110	7	have	have	VBP
cord-017161-lcqrd4v0	110	8	examined	examine	VBN
cord-017161-lcqrd4v0	110	9	T	t	NN
cord-017161-lcqrd4v0	110	10	cell	cell	NN
cord-017161-lcqrd4v0	110	11	V	v	NN
cord-017161-lcqrd4v0	110	12	b	b	NN
cord-017161-lcqrd4v0	110	13	repertoires	repertoire	NNS
cord-017161-lcqrd4v0	110	14	in	in	IN
cord-017161-lcqrd4v0	110	15	KD	KD	NNP
cord-017161-lcqrd4v0	110	16	,	,	,
cord-017161-lcqrd4v0	110	17	or	or	CC
cord-017161-lcqrd4v0	110	18	examined	examine	VBD
cord-017161-lcqrd4v0	110	19	the	the	DT
cord-017161-lcqrd4v0	110	20	prevalence	prevalence	NN
cord-017161-lcqrd4v0	110	21	of	of	IN
cord-017161-lcqrd4v0	110	22	serological	serological	JJ
cord-017161-lcqrd4v0	110	23	conversion	conversion	NN
cord-017161-lcqrd4v0	110	24	or	or	CC
cord-017161-lcqrd4v0	110	25	colonization	colonization	NN
cord-017161-lcqrd4v0	110	26	with	with	IN
cord-017161-lcqrd4v0	110	27	SAg	SAg	NNS
cord-017161-lcqrd4v0	110	28	-	-	HYPH
cord-017161-lcqrd4v0	110	29	producing	produce	VBG
cord-017161-lcqrd4v0	110	30	organisms	organism	NNS
cord-017161-lcqrd4v0	110	31	[	[	-LRB-
cord-017161-lcqrd4v0	110	32	62	62	CD
cord-017161-lcqrd4v0	110	33	,	,	,
cord-017161-lcqrd4v0	110	34	63	63	CD
cord-017161-lcqrd4v0	110	35	]	]	-RRB-
cord-017161-lcqrd4v0	110	36	.	.	.
cord-017161-lcqrd4v0	111	1	An	an	DT
cord-017161-lcqrd4v0	111	2	SAg	SAg	NNS
cord-017161-lcqrd4v0	111	3	is	be	VBZ
cord-017161-lcqrd4v0	111	4	also	also	RB
cord-017161-lcqrd4v0	111	5	responsible	responsible	JJ
cord-017161-lcqrd4v0	111	6	for	for	IN
cord-017161-lcqrd4v0	111	7	induction	induction	NN
cord-017161-lcqrd4v0	111	8	of	of	IN
cord-017161-lcqrd4v0	111	9	coronary	coronary	JJ
cord-017161-lcqrd4v0	111	10	artery	artery	NN
cord-017161-lcqrd4v0	111	11	disease	disease	NN
cord-017161-lcqrd4v0	111	12	in	in	IN
cord-017161-lcqrd4v0	111	13	a	a	DT
cord-017161-lcqrd4v0	111	14	murine	murine	JJ
cord-017161-lcqrd4v0	111	15	model	model	NN
cord-017161-lcqrd4v0	111	16	of	of	IN
cord-017161-lcqrd4v0	111	17	KD	KD	NNP
cord-017161-lcqrd4v0	111	18	(	(	-LRB-
cord-017161-lcqrd4v0	111	19	discussed	discuss	VBN
cord-017161-lcqrd4v0	111	20	in	in	IN
cord-017161-lcqrd4v0	111	21	detail	detail	NN
cord-017161-lcqrd4v0	111	22	in	in	IN
cord-017161-lcqrd4v0	111	23	the	the	DT
cord-017161-lcqrd4v0	111	24	"	"	``
cord-017161-lcqrd4v0	111	25	In	in	IN
cord-017161-lcqrd4v0	111	26	Vivo	Vivo	NNP
cord-017161-lcqrd4v0	111	27	Experimental	Experimental	NNP
cord-017161-lcqrd4v0	111	28	Data	Data	NNP
cord-017161-lcqrd4v0	111	29	in	in	IN
cord-017161-lcqrd4v0	111	30	KD	KD	NNP
cord-017161-lcqrd4v0	111	31	"	"	''
cord-017161-lcqrd4v0	111	32	section	section	NN
cord-017161-lcqrd4v0	111	33	)	)	-RRB-
cord-017161-lcqrd4v0	111	34	[	[	-LRB-
cord-017161-lcqrd4v0	111	35	55	55	CD
cord-017161-lcqrd4v0	111	36	,	,	,
cord-017161-lcqrd4v0	111	37	59	59	CD
cord-017161-lcqrd4v0	111	38	,	,	,
cord-017161-lcqrd4v0	111	39	60	60	CD
cord-017161-lcqrd4v0	111	40	]	]	-RRB-
cord-017161-lcqrd4v0	111	41	.	.	.
cord-017161-lcqrd4v0	112	1	However	however	RB
cord-017161-lcqrd4v0	112	2	,	,	,
cord-017161-lcqrd4v0	112	3	Rowley	Rowley	NNP
cord-017161-lcqrd4v0	112	4	et	et	NNP
cord-017161-lcqrd4v0	112	5	al	al	NNP
cord-017161-lcqrd4v0	112	6	.	.	.
cord-017161-lcqrd4v0	113	1	recently	recently	RB
cord-017161-lcqrd4v0	113	2	reported	report	VBD
cord-017161-lcqrd4v0	113	3	three	three	CD
cord-017161-lcqrd4v0	113	4	fatal	fatal	JJ
cord-017161-lcqrd4v0	113	5	cases	case	NNS
cord-017161-lcqrd4v0	113	6	of	of	IN
cord-017161-lcqrd4v0	113	7	KD	KD	NNP
cord-017161-lcqrd4v0	113	8	and	and	CC
cord-017161-lcqrd4v0	113	9	observed	observe	VBD
cord-017161-lcqrd4v0	113	10	IgA	IgA	NNP
cord-017161-lcqrd4v0	113	11	plasma	plasma	NN
cord-017161-lcqrd4v0	113	12	cell	cell	NN
cord-017161-lcqrd4v0	113	13	in	in	IN
cord-017161-lcqrd4v0	113	14	fi	fi	NNP
cord-017161-lcqrd4v0	113	15	ltration	ltration	NN
cord-017161-lcqrd4v0	113	16	into	into	IN
cord-017161-lcqrd4v0	113	17	the	the	DT
cord-017161-lcqrd4v0	113	18	vascular	vascular	JJ
cord-017161-lcqrd4v0	113	19	wall	wall	NN
cord-017161-lcqrd4v0	113	20	during	during	IN
cord-017161-lcqrd4v0	113	21	the	the	DT
cord-017161-lcqrd4v0	113	22	acute	acute	JJ
cord-017161-lcqrd4v0	113	23	phase	phase	NN
cord-017161-lcqrd4v0	113	24	of	of	IN
cord-017161-lcqrd4v0	113	25	the	the	DT
cord-017161-lcqrd4v0	113	26	illness	illness	NN
cord-017161-lcqrd4v0	113	27	[	[	-LRB-
cord-017161-lcqrd4v0	113	28	64	64	CD
cord-017161-lcqrd4v0	113	29	]	]	-RRB-
cord-017161-lcqrd4v0	113	30	.	.	.
cord-017161-lcqrd4v0	114	1	By	by	IN
cord-017161-lcqrd4v0	114	2	examining	examine	VBG
cord-017161-lcqrd4v0	114	3	the	the	DT
cord-017161-lcqrd4v0	114	4	clonality	clonality	NN
cord-017161-lcqrd4v0	114	5	of	of	IN
cord-017161-lcqrd4v0	114	6	this	this	DT
cord-017161-lcqrd4v0	114	7	IgA	IgA	NNP
cord-017161-lcqrd4v0	114	8	response	response	NN
cord-017161-lcqrd4v0	114	9	using	use	VBG
cord-017161-lcqrd4v0	114	10	reverse	reverse	JJ
cord-017161-lcqrd4v0	114	11	transcriptase	transcriptase	NN
cord-017161-lcqrd4v0	114	12	(	(	-LRB-
cord-017161-lcqrd4v0	114	13	RT)-PCR	rt)-pcr	FW
cord-017161-lcqrd4v0	114	14	in	in	IN
cord-017161-lcqrd4v0	114	15	lesional	lesional	JJ
cord-017161-lcqrd4v0	114	16	vascular	vascular	JJ
cord-017161-lcqrd4v0	114	17	tissue	tissue	NN
cord-017161-lcqrd4v0	114	18	,	,	,
cord-017161-lcqrd4v0	114	19	these	these	DT
cord-017161-lcqrd4v0	114	20	researchers	researcher	NNS
cord-017161-lcqrd4v0	114	21	observed	observe	VBD
cord-017161-lcqrd4v0	114	22	that	that	IN
cord-017161-lcqrd4v0	114	23	the	the	DT
cord-017161-lcqrd4v0	114	24	IgA	IgA	NNP
cord-017161-lcqrd4v0	114	25	response	response	NN
cord-017161-lcqrd4v0	114	26	was	be	VBD
cord-017161-lcqrd4v0	114	27	oligoclonal	oligoclonal	JJ
cord-017161-lcqrd4v0	114	28	,	,	,
cord-017161-lcqrd4v0	114	29	suggesting	suggest	VBG
cord-017161-lcqrd4v0	114	30	a	a	DT
cord-017161-lcqrd4v0	114	31	conventional	conventional	JJ
cord-017161-lcqrd4v0	114	32	Ag	Ag	NNP
cord-017161-lcqrd4v0	114	33	process	process	NN
cord-017161-lcqrd4v0	114	34	rather	rather	RB
cord-017161-lcqrd4v0	114	35	than	than	IN
cord-017161-lcqrd4v0	114	36	a	a	DT
cord-017161-lcqrd4v0	114	37	SAgdriven	SAgdriven	NNP
cord-017161-lcqrd4v0	114	38	one	one	CD
cord-017161-lcqrd4v0	114	39	[	[	-LRB-
cord-017161-lcqrd4v0	114	40	64	64	CD
cord-017161-lcqrd4v0	114	41	]	]	-RRB-
cord-017161-lcqrd4v0	114	42	.	.	.
cord-017161-lcqrd4v0	115	1	Although	although	IN
cord-017161-lcqrd4v0	115	2	the	the	DT
cord-017161-lcqrd4v0	115	3	debate	debate	NN
cord-017161-lcqrd4v0	115	4	continues	continue	VBZ
cord-017161-lcqrd4v0	115	5	regarding	regard	VBG
cord-017161-lcqrd4v0	115	6	the	the	DT
cord-017161-lcqrd4v0	115	7	mechanism	mechanism	NN
cord-017161-lcqrd4v0	115	8	of	of	IN
cord-017161-lcqrd4v0	115	9	initial	initial	JJ
cord-017161-lcqrd4v0	115	10	immune	immune	JJ
cord-017161-lcqrd4v0	115	11	activation	activation	NN
cord-017161-lcqrd4v0	115	12	,	,	,
cord-017161-lcqrd4v0	115	13	different	different	JJ
cord-017161-lcqrd4v0	115	14	mechanisms	mechanism	NNS
cord-017161-lcqrd4v0	115	15	are	be	VBP
cord-017161-lcqrd4v0	115	16	most	most	RBS
cord-017161-lcqrd4v0	115	17	likely	likely	RB
cord-017161-lcqrd4v0	115	18	involved	involve	VBN
cord-017161-lcqrd4v0	115	19	with	with	IN
cord-017161-lcqrd4v0	115	20	a	a	DT
cord-017161-lcqrd4v0	115	21	fi	fi	FW
cord-017161-lcqrd4v0	115	22	nal	nal	FW
cord-017161-lcqrd4v0	115	23	common	common	JJ
cord-017161-lcqrd4v0	115	24	pathway	pathway	NN
cord-017161-lcqrd4v0	115	25	of	of	IN
cord-017161-lcqrd4v0	115	26	immune	immune	JJ
cord-017161-lcqrd4v0	115	27	activation	activation	NN
cord-017161-lcqrd4v0	115	28	responsible	responsible	JJ
cord-017161-lcqrd4v0	115	29	for	for	IN
cord-017161-lcqrd4v0	115	30	this	this	DT
cord-017161-lcqrd4v0	115	31	clinical	clinical	JJ
cord-017161-lcqrd4v0	115	32	syndrome	syndrome	NN
cord-017161-lcqrd4v0	115	33	.	.	.
cord-017161-lcqrd4v0	116	1	Regardless	regardless	RB
cord-017161-lcqrd4v0	116	2	of	of	IN
cord-017161-lcqrd4v0	116	3	how	how	WRB
cord-017161-lcqrd4v0	116	4	T	t	NN
cord-017161-lcqrd4v0	116	5	cells	cell	NNS
cord-017161-lcqrd4v0	116	6	get	get	VBP
cord-017161-lcqrd4v0	116	7	activated	activate	VBN
cord-017161-lcqrd4v0	116	8	,	,	,
cord-017161-lcqrd4v0	116	9	the	the	DT
cord-017161-lcqrd4v0	116	10	massive	massive	JJ
cord-017161-lcqrd4v0	116	11	immune	immune	JJ
cord-017161-lcqrd4v0	116	12	response	response	NN
cord-017161-lcqrd4v0	116	13	characteristic	characteristic	NN
cord-017161-lcqrd4v0	116	14	of	of	IN
cord-017161-lcqrd4v0	116	15	KD	KD	NNP
cord-017161-lcqrd4v0	116	16	is	be	VBZ
cord-017161-lcqrd4v0	116	17	translated	translate	VBN
cord-017161-lcqrd4v0	116	18	into	into	IN
cord-017161-lcqrd4v0	116	19	systemic	systemic	JJ
cord-017161-lcqrd4v0	116	20	in	in	IN
cord-017161-lcqrd4v0	116	21	fl	fl	NNP
cord-017161-lcqrd4v0	116	22	ammation	ammation	NNP
cord-017161-lcqrd4v0	116	23	manifested	manifest	VBD
cord-017161-lcqrd4v0	116	24	clinically	clinically	RB
cord-017161-lcqrd4v0	116	25	as	as	IN
cord-017161-lcqrd4v0	116	26	fever	fever	NN
cord-017161-lcqrd4v0	116	27	and	and	CC
cord-017161-lcqrd4v0	116	28	the	the	DT
cord-017161-lcqrd4v0	116	29	cardiac	cardiac	NN
cord-017161-lcqrd4v0	116	30	features	feature	NNS
cord-017161-lcqrd4v0	116	31	of	of	IN
cord-017161-lcqrd4v0	116	32	KD	KD	NNP
cord-017161-lcqrd4v0	116	33	[	[	-LRB-
cord-017161-lcqrd4v0	116	34	55	55	CD
cord-017161-lcqrd4v0	116	35	]	]	-RRB-
cord-017161-lcqrd4v0	116	36	.	.	.
cord-017161-lcqrd4v0	117	1	Experimental	experimental	JJ
cord-017161-lcqrd4v0	117	2	mice	mouse	NNS
cord-017161-lcqrd4v0	117	3	develop	develop	VBP
cord-017161-lcqrd4v0	117	4	coronary	coronary	JJ
cord-017161-lcqrd4v0	117	5	arteritis	arteritis	NN
cord-017161-lcqrd4v0	117	6	in	in	IN
cord-017161-lcqrd4v0	117	7	response	response	NN
cord-017161-lcqrd4v0	117	8	to	to	IN
cord-017161-lcqrd4v0	117	9	intra	intra	JJ
cord-017161-lcqrd4v0	117	10	-	-	JJ
cord-017161-lcqrd4v0	117	11	peritoneal	peritoneal	JJ
cord-017161-lcqrd4v0	117	12	injections	injection	NNS
cord-017161-lcqrd4v0	117	13	of	of	IN
cord-017161-lcqrd4v0	117	14	Lactobacillus	lactobacillus	NN
cord-017161-lcqrd4v0	117	15	casei	casei	NN
cord-017161-lcqrd4v0	117	16	wall	wall	NN
cord-017161-lcqrd4v0	117	17	extract	extract	NN
cord-017161-lcqrd4v0	117	18	(	(	-LRB-
cord-017161-lcqrd4v0	117	19	LCWE	LCWE	NNP
cord-017161-lcqrd4v0	117	20	)	)	-RRB-
cord-017161-lcqrd4v0	117	21	with	with	IN
cord-017161-lcqrd4v0	117	22	the	the	DT
cord-017161-lcqrd4v0	117	23	resultant	resultant	JJ
cord-017161-lcqrd4v0	117	24	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	117	25	being	be	VBG
cord-017161-lcqrd4v0	117	26	similar	similar	JJ
cord-017161-lcqrd4v0	117	27	to	to	IN
cord-017161-lcqrd4v0	117	28	KD	KD	NNP
cord-017161-lcqrd4v0	117	29	in	in	IN
cord-017161-lcqrd4v0	117	30	children	child	NNS
cord-017161-lcqrd4v0	117	31	[	[	-LRB-
cord-017161-lcqrd4v0	117	32	65	65	CD
cord-017161-lcqrd4v0	117	33	,	,	,
cord-017161-lcqrd4v0	117	34	66	66	CD
cord-017161-lcqrd4v0	117	35	]	]	-RRB-
cord-017161-lcqrd4v0	117	36	.	.	.
cord-017161-lcqrd4v0	118	1	Young	young	JJ
cord-017161-lcqrd4v0	118	2	mice	mouse	NNS
cord-017161-lcqrd4v0	118	3	(	(	-LRB-
cord-017161-lcqrd4v0	118	4	age	age	NN
cord-017161-lcqrd4v0	118	5	4	4	CD
cord-017161-lcqrd4v0	118	6	-	-	SYM
cord-017161-lcqrd4v0	118	7	5	5	CD
cord-017161-lcqrd4v0	118	8	weeks	week	NNS
cord-017161-lcqrd4v0	118	9	)	)	-RRB-
cord-017161-lcqrd4v0	118	10	are	be	VBP
cord-017161-lcqrd4v0	118	11	more	more	RBR
cord-017161-lcqrd4v0	118	12	susceptible	susceptible	JJ
cord-017161-lcqrd4v0	118	13	to	to	IN
cord-017161-lcqrd4v0	118	14	LCWE	lcwe	NN
cord-017161-lcqrd4v0	118	15	-	-	HYPH
cord-017161-lcqrd4v0	118	16	induced	induce	VBN
cord-017161-lcqrd4v0	118	17	disease	disease	NN
cord-017161-lcqrd4v0	118	18	compared	compare	VBN
cord-017161-lcqrd4v0	118	19	with	with	IN
cord-017161-lcqrd4v0	118	20	older	old	JJR
cord-017161-lcqrd4v0	118	21	mice	mouse	NNS
cord-017161-lcqrd4v0	118	22	[	[	-LRB-
cord-017161-lcqrd4v0	118	23	65	65	CD
cord-017161-lcqrd4v0	118	24	]	]	-RRB-
cord-017161-lcqrd4v0	119	1	[	[	-LRB-
cord-017161-lcqrd4v0	119	2	66	66	CD
cord-017161-lcqrd4v0	119	3	]	]	-RRB-
cord-017161-lcqrd4v0	120	1	[	[	-LRB-
cord-017161-lcqrd4v0	120	2	67	67	CD
cord-017161-lcqrd4v0	120	3	]	]	-RRB-
cord-017161-lcqrd4v0	121	1	[	[	-LRB-
cord-017161-lcqrd4v0	121	2	68	68	CD
cord-017161-lcqrd4v0	121	3	]	]	-RRB-
cord-017161-lcqrd4v0	121	4	[	[	-LRB-
cord-017161-lcqrd4v0	121	5	69	69	CD
cord-017161-lcqrd4v0	121	6	]	]	-RRB-
cord-017161-lcqrd4v0	121	7	.	.	.
cord-017161-lcqrd4v0	122	1	The	the	DT
cord-017161-lcqrd4v0	122	2	peripheral	peripheral	JJ
cord-017161-lcqrd4v0	122	3	immune	immune	JJ
cord-017161-lcqrd4v0	122	4	activation	activation	NN
cord-017161-lcqrd4v0	122	5	within	within	IN
cord-017161-lcqrd4v0	122	6	hours	hour	NNS
cord-017161-lcqrd4v0	122	7	of	of	IN
cord-017161-lcqrd4v0	122	8	LCWE	lcwe	NN
cord-017161-lcqrd4v0	122	9	injection	injection	NN
cord-017161-lcqrd4v0	122	10	is	be	VBZ
cord-017161-lcqrd4v0	122	11	followed	follow	VBN
cord-017161-lcqrd4v0	122	12	by	by	IN
cord-017161-lcqrd4v0	122	13	local	local	JJ
cord-017161-lcqrd4v0	122	14	in	in	IN
cord-017161-lcqrd4v0	122	15	fi	fi	NNP
cord-017161-lcqrd4v0	122	16	ltration	ltration	NN
cord-017161-lcqrd4v0	122	17	into	into	IN
cord-017161-lcqrd4v0	122	18	cardiac	cardiac	JJ
cord-017161-lcqrd4v0	122	19	tissue	tissue	NN
cord-017161-lcqrd4v0	122	20	at	at	IN
cord-017161-lcqrd4v0	122	21	day	day	NN
cord-017161-lcqrd4v0	122	22	3	3	CD
cord-017161-lcqrd4v0	122	23	with	with	IN
cord-017161-lcqrd4v0	122	24	the	the	DT
cord-017161-lcqrd4v0	122	25	in	in	IN
cord-017161-lcqrd4v0	122	26	fl	fl	NNP
cord-017161-lcqrd4v0	122	27	ammatory	ammatory	NNP
cord-017161-lcqrd4v0	122	28	in	in	IN
cord-017161-lcqrd4v0	122	29	fi	fi	NNP
cord-017161-lcqrd4v0	122	30	ltrate	ltrate	NNP
cord-017161-lcqrd4v0	122	31	comprising	comprise	VBG
cord-017161-lcqrd4v0	122	32	mainly	mainly	RB
cord-017161-lcqrd4v0	122	33	T	T	NNP
cord-017161-lcqrd4v0	122	34	cells	cell	NNS
cord-017161-lcqrd4v0	122	35	[	[	-LRB-
cord-017161-lcqrd4v0	122	36	65	65	CD
cord-017161-lcqrd4v0	122	37	]	]	-RRB-
cord-017161-lcqrd4v0	122	38	[	[	-LRB-
cord-017161-lcqrd4v0	122	39	66	66	CD
cord-017161-lcqrd4v0	122	40	]	]	-RRB-
cord-017161-lcqrd4v0	122	41	[	[	-LRB-
cord-017161-lcqrd4v0	122	42	67	67	CD
cord-017161-lcqrd4v0	122	43	]	]	-RRB-
cord-017161-lcqrd4v0	123	1	[	[	-LRB-
cord-017161-lcqrd4v0	123	2	68	68	CD
cord-017161-lcqrd4v0	123	3	]	]	-RRB-
cord-017161-lcqrd4v0	123	4	[	[	-LRB-
cord-017161-lcqrd4v0	123	5	69	69	CD
cord-017161-lcqrd4v0	123	6	]	]	-RRB-
cord-017161-lcqrd4v0	123	7	.	.	.
cord-017161-lcqrd4v0	124	1	This	this	DT
cord-017161-lcqrd4v0	124	2	in	in	IN
cord-017161-lcqrd4v0	124	3	fl	fl	NNP
cord-017161-lcqrd4v0	124	4	ammatory	ammatory	NNP
cord-017161-lcqrd4v0	124	5	response	response	NN
cord-017161-lcqrd4v0	124	6	peaks	peak	NNS
cord-017161-lcqrd4v0	124	7	at	at	IN
cord-017161-lcqrd4v0	124	8	day	day	NN
cord-017161-lcqrd4v0	124	9	28	28	CD
cord-017161-lcqrd4v0	124	10	post	post	NN
cord-017161-lcqrd4v0	124	11	injection	injection	NN
cord-017161-lcqrd4v0	124	12	and	and	CC
cord-017161-lcqrd4v0	124	13	is	be	VBZ
cord-017161-lcqrd4v0	124	14	accompanied	accompany	VBN
cord-017161-lcqrd4v0	124	15	by	by	IN
cord-017161-lcqrd4v0	124	16	elastin	elastin	NN
cord-017161-lcqrd4v0	124	17	breakdown	breakdown	NN
cord-017161-lcqrd4v0	124	18	with	with	IN
cord-017161-lcqrd4v0	124	19	disruption	disruption	NN
cord-017161-lcqrd4v0	124	20	of	of	IN
cord-017161-lcqrd4v0	124	21	the	the	DT
cord-017161-lcqrd4v0	124	22	intima	intima	NN
cord-017161-lcqrd4v0	124	23	and	and	CC
cord-017161-lcqrd4v0	124	24	media	medium	NNS
cord-017161-lcqrd4v0	124	25	,	,	,
cord-017161-lcqrd4v0	124	26	as	as	RB
cord-017161-lcqrd4v0	124	27	well	well	RB
cord-017161-lcqrd4v0	124	28	as	as	IN
cord-017161-lcqrd4v0	124	29	aneurysm	aneurysm	NN
cord-017161-lcqrd4v0	124	30	formation	formation	NN
cord-017161-lcqrd4v0	124	31	at	at	IN
cord-017161-lcqrd4v0	124	32	day	day	NN
cord-017161-lcqrd4v0	124	33	42	42	CD
cord-017161-lcqrd4v0	124	34	[	[	-LRB-
cord-017161-lcqrd4v0	124	35	65	65	CD
cord-017161-lcqrd4v0	124	36	]	]	-RRB-
cord-017161-lcqrd4v0	124	37	[	[	-LRB-
cord-017161-lcqrd4v0	124	38	66	66	CD
cord-017161-lcqrd4v0	124	39	]	]	-RRB-
cord-017161-lcqrd4v0	124	40	[	[	-LRB-
cord-017161-lcqrd4v0	124	41	67	67	CD
cord-017161-lcqrd4v0	124	42	]	]	-RRB-
cord-017161-lcqrd4v0	124	43	[	[	-LRB-
cord-017161-lcqrd4v0	124	44	68	68	CD
cord-017161-lcqrd4v0	124	45	]	]	-RRB-
cord-017161-lcqrd4v0	124	46	[	[	-LRB-
cord-017161-lcqrd4v0	124	47	69	69	CD
cord-017161-lcqrd4v0	124	48	]	]	-RRB-
cord-017161-lcqrd4v0	124	49	.	.	.
cord-017161-lcqrd4v0	125	1	Additionally	additionally	RB
cord-017161-lcqrd4v0	125	2	,	,	,
cord-017161-lcqrd4v0	125	3	an	an	DT
cord-017161-lcqrd4v0	125	4	SAg	SAg	NNS
cord-017161-lcqrd4v0	125	5	found	find	VBN
cord-017161-lcqrd4v0	125	6	within	within	IN
cord-017161-lcqrd4v0	125	7	LCWE	LCWE	NNP
cord-017161-lcqrd4v0	125	8	contributes	contribute	VBZ
cord-017161-lcqrd4v0	125	9	signi	signi	NNP
cord-017161-lcqrd4v0	125	10	fi	fi	NNP
cord-017161-lcqrd4v0	125	11	cantly	cantly	RB
cord-017161-lcqrd4v0	125	12	to	to	IN
cord-017161-lcqrd4v0	125	13	the	the	DT
cord-017161-lcqrd4v0	125	14	development	development	NN
cord-017161-lcqrd4v0	125	15	of	of	IN
cord-017161-lcqrd4v0	125	16	vascular	vascular	JJ
cord-017161-lcqrd4v0	125	17	disease	disease	NN
cord-017161-lcqrd4v0	125	18	[	[	-LRB-
cord-017161-lcqrd4v0	125	19	60	60	CD
cord-017161-lcqrd4v0	125	20	]	]	-RRB-
cord-017161-lcqrd4v0	125	21	.	.	.
cord-017161-lcqrd4v0	126	1	The	the	DT
cord-017161-lcqrd4v0	126	2	common	common	JJ
cord-017161-lcqrd4v0	126	3	features	feature	NNS
cord-017161-lcqrd4v0	126	4	between	between	IN
cord-017161-lcqrd4v0	126	5	this	this	DT
cord-017161-lcqrd4v0	126	6	murine	murine	JJ
cord-017161-lcqrd4v0	126	7	model	model	NN
cord-017161-lcqrd4v0	126	8	and	and	CC
cord-017161-lcqrd4v0	126	9	the	the	DT
cord-017161-lcqrd4v0	126	10	human	human	JJ
cord-017161-lcqrd4v0	126	11	disease	disease	NN
cord-017161-lcqrd4v0	126	12	include	include	VBP
cord-017161-lcqrd4v0	126	13	an	an	DT
cord-017161-lcqrd4v0	126	14	infectious	infectious	JJ
cord-017161-lcqrd4v0	126	15	trigger	trigger	NN
cord-017161-lcqrd4v0	126	16	leading	lead	VBG
cord-017161-lcqrd4v0	126	17	to	to	IN
cord-017161-lcqrd4v0	126	18	immune	immune	JJ
cord-017161-lcqrd4v0	126	19	activation	activation	NN
cord-017161-lcqrd4v0	126	20	;	;	:
cord-017161-lcqrd4v0	126	21	disease	disease	NN
cord-017161-lcqrd4v0	126	22	susceptibility	susceptibility	NN
cord-017161-lcqrd4v0	126	23	in	in	IN
cord-017161-lcqrd4v0	126	24	the	the	DT
cord-017161-lcqrd4v0	126	25	young	young	JJ
cord-017161-lcqrd4v0	126	26	;	;	:
cord-017161-lcqrd4v0	126	27	a	a	DT
cord-017161-lcqrd4v0	126	28	time	time	NN
cord-017161-lcqrd4v0	126	29	course	course	NN
cord-017161-lcqrd4v0	126	30	similar	similar	JJ
cord-017161-lcqrd4v0	126	31	to	to	IN
cord-017161-lcqrd4v0	126	32	that	that	DT
cord-017161-lcqrd4v0	126	33	seen	see	VBN
cord-017161-lcqrd4v0	126	34	clinically	clinically	RB
cord-017161-lcqrd4v0	126	35	in	in	IN
cord-017161-lcqrd4v0	126	36	KD	KD	NNP
cord-017161-lcqrd4v0	126	37	;	;	:
cord-017161-lcqrd4v0	126	38	similar	similar	JJ
cord-017161-lcqrd4v0	126	39	pathology	pathology	NN
cord-017161-lcqrd4v0	126	40	of	of	IN
cord-017161-lcqrd4v0	126	41	coronary	coronary	JJ
cord-017161-lcqrd4v0	126	42	arteritis	arteritis	NN
cord-017161-lcqrd4v0	126	43	;	;	:
cord-017161-lcqrd4v0	126	44	and	and	CC
cord-017161-lcqrd4v0	126	45	response	response	NN
cord-017161-lcqrd4v0	126	46	to	to	IN
cord-017161-lcqrd4v0	126	47	intravenous	intravenous	JJ
cord-017161-lcqrd4v0	126	48	immunoglobulin	immunoglobulin	NN
cord-017161-lcqrd4v0	126	49	(	(	-LRB-
cord-017161-lcqrd4v0	126	50	IVIG	IVIG	NNP
cord-017161-lcqrd4v0	126	51	)	)	-RRB-
cord-017161-lcqrd4v0	126	52	treatment	treatment	NN
cord-017161-lcqrd4v0	126	53	[	[	-LRB-
cord-017161-lcqrd4v0	126	54	55	55	CD
cord-017161-lcqrd4v0	126	55	]	]	-RRB-
cord-017161-lcqrd4v0	126	56	.	.	.
cord-017161-lcqrd4v0	127	1	The	the	DT
cord-017161-lcqrd4v0	127	2	proposed	propose	VBN
cord-017161-lcqrd4v0	127	3	disease	disease	NN
cord-017161-lcqrd4v0	127	4	model	model	NN
cord-017161-lcqrd4v0	127	5	supported	support	VBN
cord-017161-lcqrd4v0	127	6	by	by	IN
cord-017161-lcqrd4v0	127	7	the	the	DT
cord-017161-lcqrd4v0	127	8	in	in	IN
cord-017161-lcqrd4v0	127	9	vivo	vivo	NNP
cord-017161-lcqrd4v0	127	10	experimental	experimental	JJ
cord-017161-lcqrd4v0	127	11	data	datum	NNS
cord-017161-lcqrd4v0	127	12	in	in	IN
cord-017161-lcqrd4v0	127	13	this	this	DT
cord-017161-lcqrd4v0	127	14	mouse	mouse	NN
cord-017161-lcqrd4v0	127	15	model	model	NN
cord-017161-lcqrd4v0	127	16	begins	begin	VBZ
cord-017161-lcqrd4v0	127	17	with	with	IN
cord-017161-lcqrd4v0	127	18	immune	immune	JJ
cord-017161-lcqrd4v0	127	19	activation	activation	NN
cord-017161-lcqrd4v0	127	20	by	by	IN
cord-017161-lcqrd4v0	127	21	a	a	DT
cord-017161-lcqrd4v0	127	22	microbe	microbe	NN
cord-017161-lcqrd4v0	127	23	with	with	IN
cord-017161-lcqrd4v0	127	24	superantigenic	superantigenic	JJ
cord-017161-lcqrd4v0	127	25	activity	activity	NN
cord-017161-lcqrd4v0	127	26	[	[	-LRB-
cord-017161-lcqrd4v0	127	27	55	55	CD
cord-017161-lcqrd4v0	127	28	]	]	-RRB-
cord-017161-lcqrd4v0	127	29	.	.	.
cord-017161-lcqrd4v0	128	1	The	the	DT
cord-017161-lcqrd4v0	128	2	SAg	SAg	NNS
cord-017161-lcqrd4v0	128	3	found	find	VBN
cord-017161-lcqrd4v0	128	4	in	in	IN
cord-017161-lcqrd4v0	128	5	the	the	DT
cord-017161-lcqrd4v0	128	6	LCWE	LCWE	NNP
cord-017161-lcqrd4v0	128	7	preferentially	preferentially	RB
cord-017161-lcqrd4v0	128	8	expands	expand	VBZ
cord-017161-lcqrd4v0	128	9	T	t	NN
cord-017161-lcqrd4v0	128	10	-	-	HYPH
cord-017161-lcqrd4v0	128	11	lymphocytes	lymphocyte	NNS
cord-017161-lcqrd4v0	128	12	expressing	express	VBG
cord-017161-lcqrd4v0	128	13	TCRV	TCRV	NNP
cord-017161-lcqrd4v0	128	14	b	b	NNP
cord-017161-lcqrd4v0	128	15	2	2	CD
cord-017161-lcqrd4v0	128	16	,	,	,
cord-017161-lcqrd4v0	128	17	4	4	CD
cord-017161-lcqrd4v0	128	18	,	,	,
cord-017161-lcqrd4v0	128	19	6	6	CD
cord-017161-lcqrd4v0	128	20	and	and	CC
cord-017161-lcqrd4v0	128	21	14	14	CD
cord-017161-lcqrd4v0	128	22	positive	positive	JJ
cord-017161-lcqrd4v0	128	23	T	t	NN
cord-017161-lcqrd4v0	128	24	cells	cell	NNS
cord-017161-lcqrd4v0	128	25	,	,	,
cord-017161-lcqrd4v0	128	26	and	and	CC
cord-017161-lcqrd4v0	128	27	this	this	DT
cord-017161-lcqrd4v0	128	28	superantigenic	superantigenic	JJ
cord-017161-lcqrd4v0	128	29	activity	activity	NN
cord-017161-lcqrd4v0	128	30	is	be	VBZ
cord-017161-lcqrd4v0	128	31	directly	directly	RB
cord-017161-lcqrd4v0	128	32	correlated	correlate	VBN
cord-017161-lcqrd4v0	128	33	with	with	IN
cord-017161-lcqrd4v0	128	34	the	the	DT
cord-017161-lcqrd4v0	128	35	ability	ability	NN
cord-017161-lcqrd4v0	128	36	to	to	TO
cord-017161-lcqrd4v0	128	37	induce	induce	VB
cord-017161-lcqrd4v0	128	38	coronary	coronary	JJ
cord-017161-lcqrd4v0	128	39	arteritis	arteritis	NN
cord-017161-lcqrd4v0	128	40	in	in	IN
cord-017161-lcqrd4v0	128	41	mice	mouse	NNS
cord-017161-lcqrd4v0	128	42	[	[	-LRB-
cord-017161-lcqrd4v0	128	43	60	60	CD
cord-017161-lcqrd4v0	128	44	]	]	-RRB-
cord-017161-lcqrd4v0	128	45	.	.	.
cord-017161-lcqrd4v0	129	1	Ablation	ablation	NN
cord-017161-lcqrd4v0	129	2	of	of	IN
cord-017161-lcqrd4v0	129	3	IFN	IFN	NNP
cord-017161-lcqrd4v0	129	4	-	-	HYPH
cord-017161-lcqrd4v0	129	5	g	g	NN
cord-017161-lcqrd4v0	129	6	con	con	NN
cord-017161-lcqrd4v0	129	7	fi	fi	NN
cord-017161-lcqrd4v0	129	8	rmed	rme	VBN
cord-017161-lcqrd4v0	129	9	that	that	IN
cord-017161-lcqrd4v0	129	10	IFN	IFN	NNP
cord-017161-lcqrd4v0	129	11	-	-	HYPH
cord-017161-lcqrd4v0	129	12	g	g	NNP
cord-017161-lcqrd4v0	129	13	plays	play	VBZ
cord-017161-lcqrd4v0	129	14	an	an	DT
cord-017161-lcqrd4v0	129	15	important	important	JJ
cord-017161-lcqrd4v0	129	16	regulatory	regulatory	JJ
cord-017161-lcqrd4v0	129	17	role	role	NN
cord-017161-lcqrd4v0	129	18	in	in	IN
cord-017161-lcqrd4v0	129	19	disease	disease	NN
cord-017161-lcqrd4v0	129	20	induction	induction	NN
cord-017161-lcqrd4v0	129	21	in	in	IN
cord-017161-lcqrd4v0	129	22	this	this	DT
cord-017161-lcqrd4v0	129	23	disease	disease	NN
cord-017161-lcqrd4v0	129	24	model	model	NN
cord-017161-lcqrd4v0	129	25	[	[	-LRB-
cord-017161-lcqrd4v0	129	26	55	55	CD
cord-017161-lcqrd4v0	129	27	]	]	-RRB-
cord-017161-lcqrd4v0	129	28	.	.	.
cord-017161-lcqrd4v0	130	1	Mice	mouse	NNS
cord-017161-lcqrd4v0	130	2	with	with	IN
cord-017161-lcqrd4v0	130	3	absence	absence	NN
cord-017161-lcqrd4v0	130	4	of	of	IN
cord-017161-lcqrd4v0	130	5	TNF	TNF	NNP
cord-017161-lcqrd4v0	130	6	-	-	:
cord-017161-lcqrd4v0	130	7	a	a	DT
cord-017161-lcqrd4v0	130	8	activity	activity	NN
cord-017161-lcqrd4v0	130	9	(	(	-LRB-
cord-017161-lcqrd4v0	130	10	blockade	blockade	NN
cord-017161-lcqrd4v0	130	11	of	of	IN
cord-017161-lcqrd4v0	130	12	TNF	TNF	NNP
cord-017161-lcqrd4v0	130	13	-	-	:
cord-017161-lcqrd4v0	130	14	a	a	LS
cord-017161-lcqrd4v0	130	15	)	)	-RRB-
cord-017161-lcqrd4v0	130	16	or	or	CC
cord-017161-lcqrd4v0	130	17	TNFR1	TNFR1	NNP
cord-017161-lcqrd4v0	130	18	knockouts	knockouts	NNP
cord-017161-lcqrd4v0	130	19	)	)	-RRB-
cord-017161-lcqrd4v0	130	20	do	do	VBP
cord-017161-lcqrd4v0	130	21	not	not	RB
cord-017161-lcqrd4v0	130	22	develop	develop	VB
cord-017161-lcqrd4v0	130	23	coronary	coronary	JJ
cord-017161-lcqrd4v0	130	24	disease	disease	NN
cord-017161-lcqrd4v0	130	25	after	after	IN
cord-017161-lcqrd4v0	130	26	LCWE	LCWE	NNP
cord-017161-lcqrd4v0	130	27	stimulation	stimulation	NN
cord-017161-lcqrd4v0	130	28	[	[	-LRB-
cord-017161-lcqrd4v0	130	29	68	68	CD
cord-017161-lcqrd4v0	130	30	]	]	-RRB-
cord-017161-lcqrd4v0	130	31	.	.	.
cord-017161-lcqrd4v0	131	1	Of	of	IN
cord-017161-lcqrd4v0	131	2	note	note	NN
cord-017161-lcqrd4v0	131	3	,	,	,
cord-017161-lcqrd4v0	131	4	the	the	DT
cord-017161-lcqrd4v0	131	5	T	t	NN
cord-017161-lcqrd4v0	131	6	cells	cell	NNS
cord-017161-lcqrd4v0	131	7	found	find	VBN
cord-017161-lcqrd4v0	131	8	in	in	IN
cord-017161-lcqrd4v0	131	9	affected	affected	JJ
cord-017161-lcqrd4v0	131	10	vessels	vessel	NNS
cord-017161-lcqrd4v0	131	11	express	express	VBP
cord-017161-lcqrd4v0	131	12	SAg	SAg	NNS
cord-017161-lcqrd4v0	131	13	-	-	HYPH
cord-017161-lcqrd4v0	131	14	reactive	reactive	JJ
cord-017161-lcqrd4v0	131	15	TCRV	TCRV	NNP
cord-017161-lcqrd4v0	131	16	b	b	IN
cord-017161-lcqrd4v0	131	17	families	family	NNS
cord-017161-lcqrd4v0	131	18	,	,	,
cord-017161-lcqrd4v0	131	19	an	an	DT
cord-017161-lcqrd4v0	131	20	unexpected	unexpected	JJ
cord-017161-lcqrd4v0	131	21	fi	fi	NN
cord-017161-lcqrd4v0	131	22	nding	nding	NN
cord-017161-lcqrd4v0	131	23	considering	consider	VBG
cord-017161-lcqrd4v0	131	24	the	the	DT
cord-017161-lcqrd4v0	131	25	usual	usual	JJ
cord-017161-lcqrd4v0	131	26	fate	fate	NN
cord-017161-lcqrd4v0	131	27	of	of	IN
cord-017161-lcqrd4v0	131	28	SAg	SAg	NNS
cord-017161-lcqrd4v0	131	29	-	-	HYPH
cord-017161-lcqrd4v0	131	30	activated	activate	VBN
cord-017161-lcqrd4v0	131	31	T	t	NN
cord-017161-lcqrd4v0	131	32	cells	cell	NNS
cord-017161-lcqrd4v0	131	33	,	,	,
cord-017161-lcqrd4v0	131	34	which	which	WDT
cord-017161-lcqrd4v0	131	35	are	be	VBP
cord-017161-lcqrd4v0	131	36	actively	actively	RB
cord-017161-lcqrd4v0	131	37	deleted	delete	VBN
cord-017161-lcqrd4v0	131	38	by	by	IN
cord-017161-lcqrd4v0	131	39	apoptosis	apoptosis	NN
cord-017161-lcqrd4v0	131	40	.	.	.
cord-017161-lcqrd4v0	132	1	Moolani	Moolani	NNP
cord-017161-lcqrd4v0	132	2	et	et	NNP
cord-017161-lcqrd4v0	132	3	al	al	NNP
cord-017161-lcqrd4v0	132	4	.	.	NNP
cord-017161-lcqrd4v0	132	5	have	have	VBP
cord-017161-lcqrd4v0	132	6	shown	show	VBN
cord-017161-lcqrd4v0	132	7	that	that	IN
cord-017161-lcqrd4v0	132	8	co	co	NN
cord-017161-lcqrd4v0	132	9	-	-	NN
cord-017161-lcqrd4v0	132	10	stimulation	stimulation	NN
cord-017161-lcqrd4v0	132	11	can	can	MD
cord-017161-lcqrd4v0	132	12	rescue	rescue	VB
cord-017161-lcqrd4v0	132	13	SAg	SAg	NNS
cord-017161-lcqrd4v0	132	14	-	-	HYPH
cord-017161-lcqrd4v0	132	15	stimulated	stimulate	VBN
cord-017161-lcqrd4v0	132	16	T	t	NN
cord-017161-lcqrd4v0	132	17	cells	cell	NNS
cord-017161-lcqrd4v0	132	18	from	from	IN
cord-017161-lcqrd4v0	132	19	apoptosis	apoptosis	NN
cord-017161-lcqrd4v0	132	20	[	[	-LRB-
cord-017161-lcqrd4v0	132	21	70	70	CD
cord-017161-lcqrd4v0	132	22	]	]	-RRB-
cord-017161-lcqrd4v0	132	23	.	.	.
cord-017161-lcqrd4v0	133	1	Furthermore	furthermore	RB
cord-017161-lcqrd4v0	133	2	,	,	,
cord-017161-lcqrd4v0	133	3	the	the	DT
cord-017161-lcqrd4v0	133	4	coronary	coronary	JJ
cord-017161-lcqrd4v0	133	5	endothelium	endothelium	NN
cord-017161-lcqrd4v0	133	6	is	be	VBZ
cord-017161-lcqrd4v0	133	7	transformed	transform	VBN
cord-017161-lcqrd4v0	133	8	into	into	IN
cord-017161-lcqrd4v0	133	9	a	a	DT
cord-017161-lcqrd4v0	133	10	professional	professional	JJ
cord-017161-lcqrd4v0	133	11	antigen	antigen	NN
cord-017161-lcqrd4v0	133	12	-	-	HYPH
cord-017161-lcqrd4v0	133	13	presenting	present	VBG
cord-017161-lcqrd4v0	133	14	cell	cell	NN
cord-017161-lcqrd4v0	133	15	(	(	-LRB-
cord-017161-lcqrd4v0	133	16	APC	APC	NNP
cord-017161-lcqrd4v0	133	17	)	)	-RRB-
cord-017161-lcqrd4v0	133	18	by	by	IN
cord-017161-lcqrd4v0	133	19	upregulation	upregulation	NN
cord-017161-lcqrd4v0	133	20	of	of	IN
cord-017161-lcqrd4v0	133	21	co	co	JJ
cord-017161-lcqrd4v0	133	22	-	-	JJ
cord-017161-lcqrd4v0	133	23	stimulatory	stimulatory	JJ
cord-017161-lcqrd4v0	133	24	molecules	molecule	NNS
cord-017161-lcqrd4v0	133	25	driven	drive	VBN
cord-017161-lcqrd4v0	133	26	partially	partially	RB
cord-017161-lcqrd4v0	133	27	by	by	IN
cord-017161-lcqrd4v0	133	28	the	the	DT
cord-017161-lcqrd4v0	133	29	tissue	tissue	NN
cord-017161-lcqrd4v0	133	30	-	-	HYPH
cord-017161-lcqrd4v0	133	31	speci	speci	FW
cord-017161-lcqrd4v0	133	32	fi	fi	NN
cord-017161-lcqrd4v0	133	33	c	c	NN
cord-017161-lcqrd4v0	133	34	expression	expression	NN
cord-017161-lcqrd4v0	133	35	of	of	IN
cord-017161-lcqrd4v0	133	36	Toll	Toll	NNP
cord-017161-lcqrd4v0	133	37	-	-	HYPH
cord-017161-lcqrd4v0	133	38	like	like	JJ
cord-017161-lcqrd4v0	133	39	receptor	receptor	NN
cord-017161-lcqrd4v0	133	40	(	(	-LRB-
cord-017161-lcqrd4v0	133	41	TLR	TLR	NNP
cord-017161-lcqrd4v0	133	42	)	)	-RRB-
cord-017161-lcqrd4v0	133	43	[	[	-LRB-
cord-017161-lcqrd4v0	133	44	55	55	CD
cord-017161-lcqrd4v0	133	45	]	]	-RRB-
cord-017161-lcqrd4v0	133	46	.	.	.
cord-017161-lcqrd4v0	134	1	Increased	increase	VBN
cord-017161-lcqrd4v0	134	2	TLR2	TLR2	NNP
cord-017161-lcqrd4v0	134	3	expression	expression	NN
cord-017161-lcqrd4v0	134	4	in	in	IN
cord-017161-lcqrd4v0	134	5	conjunction	conjunction	NN
cord-017161-lcqrd4v0	134	6	with	with	IN
cord-017161-lcqrd4v0	134	7	TLR2	TLR2	NNP
cord-017161-lcqrd4v0	134	8	stimulation	stimulation	NN
cord-017161-lcqrd4v0	134	9	by	by	IN
cord-017161-lcqrd4v0	134	10	the	the	DT
cord-017161-lcqrd4v0	134	11	TLR2	TLR2	NNP
cord-017161-lcqrd4v0	134	12	ligand	ligand	NN
cord-017161-lcqrd4v0	134	13	in	in	IN
cord-017161-lcqrd4v0	134	14	LCWE	LCWE	NNP
cord-017161-lcqrd4v0	134	15	leads	lead	VBZ
cord-017161-lcqrd4v0	134	16	to	to	IN
cord-017161-lcqrd4v0	134	17	increased	increase	VBN
cord-017161-lcqrd4v0	134	18	expression	expression	NN
cord-017161-lcqrd4v0	134	19	of	of	IN
cord-017161-lcqrd4v0	134	20	co	co	JJ
cord-017161-lcqrd4v0	134	21	-	-	JJ
cord-017161-lcqrd4v0	134	22	stimulatory	stimulatory	JJ
cord-017161-lcqrd4v0	134	23	molecules	molecule	NNS
cord-017161-lcqrd4v0	134	24	facilitating	facilitate	VBG
cord-017161-lcqrd4v0	134	25	rescue	rescue	NN
cord-017161-lcqrd4v0	134	26	of	of	IN
cord-017161-lcqrd4v0	134	27	SAg	SAg	NNS
cord-017161-lcqrd4v0	134	28	-	-	HYPH
cord-017161-lcqrd4v0	134	29	activated	activate	VBN
cord-017161-lcqrd4v0	134	30	T	T	NNP
cord-017161-lcqrd4v0	134	31	cells	cell	NNS
cord-017161-lcqrd4v0	134	32	and	and	CC
cord-017161-lcqrd4v0	134	33	continued	continue	VBN
cord-017161-lcqrd4v0	134	34	local	local	JJ
cord-017161-lcqrd4v0	134	35	production	production	NN
cord-017161-lcqrd4v0	134	36	of	of	IN
cord-017161-lcqrd4v0	134	37	proin	proin	NNP
cord-017161-lcqrd4v0	134	38	fl	fl	NNP
cord-017161-lcqrd4v0	134	39	ammatory	ammatory	NNP
cord-017161-lcqrd4v0	134	40	cytokines	cytokine	NNS
cord-017161-lcqrd4v0	134	41	[	[	-LRB-
cord-017161-lcqrd4v0	134	42	71	71	CD
cord-017161-lcqrd4v0	134	43	,	,	,
cord-017161-lcqrd4v0	134	44	72	72	CD
cord-017161-lcqrd4v0	134	45	]	]	-RRB-
cord-017161-lcqrd4v0	134	46	.	.	.
cord-017161-lcqrd4v0	135	1	This	this	DT
cord-017161-lcqrd4v0	135	2	leads	lead	VBZ
cord-017161-lcqrd4v0	135	3	to	to	IN
cord-017161-lcqrd4v0	135	4	further	further	JJ
cord-017161-lcqrd4v0	135	5	exacerbation	exacerbation	NN
cord-017161-lcqrd4v0	135	6	of	of	IN
cord-017161-lcqrd4v0	135	7	the	the	DT
cord-017161-lcqrd4v0	135	8	in	in	IN
cord-017161-lcqrd4v0	135	9	fl	fl	NNP
cord-017161-lcqrd4v0	135	10	ammation	ammation	NN
cord-017161-lcqrd4v0	135	11	at	at	IN
cord-017161-lcqrd4v0	135	12	the	the	DT
cord-017161-lcqrd4v0	135	13	coronary	coronary	JJ
cord-017161-lcqrd4v0	135	14	vessel	vessel	NN
cord-017161-lcqrd4v0	135	15	wall	wall	NN
cord-017161-lcqrd4v0	135	16	[	[	-LRB-
cord-017161-lcqrd4v0	135	17	55	55	CD
cord-017161-lcqrd4v0	135	18	]	]	-RRB-
cord-017161-lcqrd4v0	135	19	.	.	.
cord-017161-lcqrd4v0	136	1	IFN	IFN	NNP
cord-017161-lcqrd4v0	136	2	-	-	HYPH
cord-017161-lcqrd4v0	136	3	g	g	NNP
cord-017161-lcqrd4v0	136	4	and	and	CC
cord-017161-lcqrd4v0	136	5	TNF	TNF	NNP
cord-017161-lcqrd4v0	136	6	-	-	,
cord-017161-lcqrd4v0	136	7	a	a	NNP
cord-017161-lcqrd4v0	136	8	are	be	VBP
cord-017161-lcqrd4v0	136	9	involved	involve	VBN
cord-017161-lcqrd4v0	136	10	in	in	IN
cord-017161-lcqrd4v0	136	11	transcriptional	transcriptional	JJ
cord-017161-lcqrd4v0	136	12	regulation	regulation	NN
cord-017161-lcqrd4v0	136	13	of	of	IN
cord-017161-lcqrd4v0	136	14	matrix	matrix	NN
cord-017161-lcqrd4v0	136	15	metalloproteinases	metalloproteinase	NNS
cord-017161-lcqrd4v0	136	16	(	(	-LRB-
cord-017161-lcqrd4v0	136	17	MMPs	MMPs	NNP
cord-017161-lcqrd4v0	136	18	)	)	-RRB-
cord-017161-lcqrd4v0	136	19	,	,	,
cord-017161-lcqrd4v0	136	20	with	with	IN
cord-017161-lcqrd4v0	136	21	TNF	TNF	NNP
cord-017161-lcqrd4v0	136	22	-	-	:
cord-017161-lcqrd4v0	136	23	a	a	DT
cord-017161-lcqrd4v0	136	24	upregulating	upregulating	NN
cord-017161-lcqrd4v0	136	25	,	,	,
cord-017161-lcqrd4v0	136	26	and	and	CC
cord-017161-lcqrd4v0	136	27	IFN	IFN	NNP
cord-017161-lcqrd4v0	136	28	-	-	HYPH
cord-017161-lcqrd4v0	136	29	g	g	NNP
cord-017161-lcqrd4v0	136	30	inhibiting	inhibit	VBG
cord-017161-lcqrd4v0	136	31	production	production	NN
cord-017161-lcqrd4v0	136	32	of	of	IN
cord-017161-lcqrd4v0	136	33	MMP-9	MMP-9	NNP
cord-017161-lcqrd4v0	136	34	[	[	-LRB-
cord-017161-lcqrd4v0	136	35	55	55	CD
cord-017161-lcqrd4v0	136	36	,	,	,
cord-017161-lcqrd4v0	136	37	73	73	CD
cord-017161-lcqrd4v0	136	38	]	]	-RRB-
cord-017161-lcqrd4v0	136	39	.	.	.
cord-017161-lcqrd4v0	137	1	Following	follow	VBG
cord-017161-lcqrd4v0	137	2	that	that	IN
cord-017161-lcqrd4v0	137	3	,	,	,
cord-017161-lcqrd4v0	137	4	the	the	DT
cord-017161-lcqrd4v0	137	5	enzymatic	enzymatic	JJ
cord-017161-lcqrd4v0	137	6	activity	activity	NN
cord-017161-lcqrd4v0	137	7	of	of	IN
cord-017161-lcqrd4v0	137	8	MMP-9	MMP-9	NNP
cord-017161-lcqrd4v0	137	9	leads	lead	VBZ
cord-017161-lcqrd4v0	137	10	to	to	IN
cord-017161-lcqrd4v0	137	11	elastin	elastin	NN
cord-017161-lcqrd4v0	137	12	breakdown	breakdown	NN
cord-017161-lcqrd4v0	137	13	and	and	CC
cord-017161-lcqrd4v0	137	14	aneurysm	aneurysm	NN
cord-017161-lcqrd4v0	137	15	formation	formation	NN
cord-017161-lcqrd4v0	137	16	[	[	-LRB-
cord-017161-lcqrd4v0	137	17	73	73	CD
cord-017161-lcqrd4v0	137	18	]	]	-RRB-
cord-017161-lcqrd4v0	137	19	.	.	.
cord-017161-lcqrd4v0	138	1	Of	of	IN
cord-017161-lcqrd4v0	138	2	note	note	NN
cord-017161-lcqrd4v0	138	3	,	,	,
cord-017161-lcqrd4v0	138	4	recently	recently	RB
cord-017161-lcqrd4v0	138	5	Alvira	Alvira	NNP
cord-017161-lcqrd4v0	138	6	et	et	FW
cord-017161-lcqrd4v0	138	7	al	al	NNP
cord-017161-lcqrd4v0	138	8	.	.	NNP
cord-017161-lcqrd4v0	138	9	have	have	VBP
cord-017161-lcqrd4v0	138	10	shown	show	VBN
cord-017161-lcqrd4v0	138	11	that	that	IN
cord-017161-lcqrd4v0	138	12	in	in	IN
cord-017161-lcqrd4v0	138	13	the	the	DT
cord-017161-lcqrd4v0	138	14	coronary	coronary	JJ
cord-017161-lcqrd4v0	138	15	arteritis	arteritis	NN
cord-017161-lcqrd4v0	138	16	associated	associate	VBN
cord-017161-lcqrd4v0	138	17	with	with	IN
cord-017161-lcqrd4v0	138	18	KD	KD	NNP
cord-017161-lcqrd4v0	138	19	,	,	,
cord-017161-lcqrd4v0	138	20	TGF	TGF	NNP
cord-017161-lcqrd4v0	138	21	-	-	HYPH
cord-017161-lcqrd4v0	138	22	b	b	NNP
cord-017161-lcqrd4v0	138	23	suppresses	suppress	VBZ
cord-017161-lcqrd4v0	138	24	elastin	elastin	NN
cord-017161-lcqrd4v0	138	25	degradation	degradation	NN
cord-017161-lcqrd4v0	138	26	by	by	IN
cord-017161-lcqrd4v0	138	27	inhibiting	inhibit	VBG
cord-017161-lcqrd4v0	138	28	plasmin	plasmin	NN
cord-017161-lcqrd4v0	138	29	-	-	HYPH
cord-017161-lcqrd4v0	138	30	mediated	mediate	VBN
cord-017161-lcqrd4v0	138	31	MMP-9	MMP-9	NNP
cord-017161-lcqrd4v0	138	32	activation	activation	NN
cord-017161-lcqrd4v0	138	33	[	[	-LRB-
cord-017161-lcqrd4v0	138	34	74	74	CD
cord-017161-lcqrd4v0	138	35	]	]	-RRB-
cord-017161-lcqrd4v0	138	36	.	.	.
cord-017161-lcqrd4v0	139	1	Thus	thus	RB
cord-017161-lcqrd4v0	139	2	,	,	,
cord-017161-lcqrd4v0	139	3	strategies	strategy	NNS
cord-017161-lcqrd4v0	139	4	to	to	TO
cord-017161-lcqrd4v0	139	5	block	block	VB
cord-017161-lcqrd4v0	139	6	TGF	TGF	NNP
cord-017161-lcqrd4v0	139	7	-	-	HYPH
cord-017161-lcqrd4v0	139	8	b	b	NNP
cord-017161-lcqrd4v0	139	9	,	,	,
cord-017161-lcqrd4v0	139	10	used	use	VBN
cord-017161-lcqrd4v0	139	11	in	in	IN
cord-017161-lcqrd4v0	139	12	those	those	DT
cord-017161-lcqrd4v0	139	13	with	with	IN
cord-017161-lcqrd4v0	139	14	Marfan	Marfan	NNP
cord-017161-lcqrd4v0	139	15	syndrome	syndrome	NN
cord-017161-lcqrd4v0	139	16	,	,	,
cord-017161-lcqrd4v0	139	17	are	be	VBP
cord-017161-lcqrd4v0	139	18	unlikely	unlikely	JJ
cord-017161-lcqrd4v0	139	19	to	to	TO
cord-017161-lcqrd4v0	139	20	be	be	VB
cord-017161-lcqrd4v0	139	21	bene	bene	NNP
cord-017161-lcqrd4v0	139	22	fi	fi	NN
cord-017161-lcqrd4v0	139	23	cial	cial	NN
cord-017161-lcqrd4v0	139	24	in	in	IN
cord-017161-lcqrd4v0	139	25	KD	KD	NNP
cord-017161-lcqrd4v0	139	26	as	as	IN
cord-017161-lcqrd4v0	139	27	they	-PRON-	PRP
cord-017161-lcqrd4v0	139	28	lead	lead	VBP
cord-017161-lcqrd4v0	139	29	to	to	IN
cord-017161-lcqrd4v0	139	30	worsening	worsen	VBG
cord-017161-lcqrd4v0	139	31	of	of	IN
cord-017161-lcqrd4v0	139	32	elastin	elastin	NN
cord-017161-lcqrd4v0	139	33	degradation	degradation	NN
cord-017161-lcqrd4v0	139	34	in	in	IN
cord-017161-lcqrd4v0	139	35	this	this	DT
cord-017161-lcqrd4v0	139	36	murine	murine	JJ
cord-017161-lcqrd4v0	139	37	model	model	NN
cord-017161-lcqrd4v0	139	38	of	of	IN
cord-017161-lcqrd4v0	139	39	KD	KD	NNP
cord-017161-lcqrd4v0	139	40	[	[	-LRB-
cord-017161-lcqrd4v0	139	41	74	74	CD
cord-017161-lcqrd4v0	139	42	]	]	-RRB-
cord-017161-lcqrd4v0	139	43	.	.	.
cord-017161-lcqrd4v0	140	1	So	so	RB
cord-017161-lcqrd4v0	140	2	in	in	IN
cord-017161-lcqrd4v0	140	3	summary	summary	NN
cord-017161-lcqrd4v0	140	4	,	,	,
cord-017161-lcqrd4v0	140	5	a	a	DT
cord-017161-lcqrd4v0	140	6	sustained	sustained	JJ
cord-017161-lcqrd4v0	140	7	local	local	JJ
cord-017161-lcqrd4v0	140	8	immune	immune	JJ
cord-017161-lcqrd4v0	140	9	response	response	NN
cord-017161-lcqrd4v0	140	10	together	together	RB
cord-017161-lcqrd4v0	140	11	with	with	IN
cord-017161-lcqrd4v0	140	12	persistent	persistent	JJ
cord-017161-lcqrd4v0	140	13	TNF	TNF	NNP
cord-017161-lcqrd4v0	140	14	-	-	:
cord-017161-lcqrd4v0	140	15	a	a	DT
cord-017161-lcqrd4v0	140	16	production	production	NN
cord-017161-lcqrd4v0	140	17	and	and	CC
cord-017161-lcqrd4v0	140	18	leucocyte	leucocyte	NN
cord-017161-lcqrd4v0	140	19	recruitment	recruitment	NN
cord-017161-lcqrd4v0	140	20	lead	lead	VBP
cord-017161-lcqrd4v0	140	21	to	to	IN
cord-017161-lcqrd4v0	140	22	upregulation	upregulation	NN
cord-017161-lcqrd4v0	140	23	of	of	IN
cord-017161-lcqrd4v0	140	24	proteolytic	proteolytic	JJ
cord-017161-lcqrd4v0	140	25	activity	activity	NN
cord-017161-lcqrd4v0	140	26	,	,	,
cord-017161-lcqrd4v0	140	27	elastin	elastin	NN
cord-017161-lcqrd4v0	140	28	degradation	degradation	NN
cord-017161-lcqrd4v0	140	29	,	,	,
cord-017161-lcqrd4v0	140	30	vessel	vessel	NN
cord-017161-lcqrd4v0	140	31	wall	wall	NN
cord-017161-lcqrd4v0	140	32	damage	damage	NN
cord-017161-lcqrd4v0	140	33	and	and	CC
cord-017161-lcqrd4v0	140	34	the	the	DT
cord-017161-lcqrd4v0	140	35	characteristic	characteristic	JJ
cord-017161-lcqrd4v0	140	36	coronary	coronary	JJ
cord-017161-lcqrd4v0	140	37	artery	artery	NN
cord-017161-lcqrd4v0	140	38	lesions	lesion	NNS
cord-017161-lcqrd4v0	140	39	seen	see	VBN
cord-017161-lcqrd4v0	140	40	in	in	IN
cord-017161-lcqrd4v0	140	41	KD	KD	NNP
cord-017161-lcqrd4v0	140	42	[	[	-LRB-
cord-017161-lcqrd4v0	140	43	55	55	CD
cord-017161-lcqrd4v0	140	44	]	]	-RRB-
cord-017161-lcqrd4v0	140	45	.	.	.
cord-017161-lcqrd4v0	141	1	Although	although	IN
cord-017161-lcqrd4v0	141	2	the	the	DT
cord-017161-lcqrd4v0	141	3	clinical	clinical	JJ
cord-017161-lcqrd4v0	141	4	syndrome	syndrome	NN
cord-017161-lcqrd4v0	141	5	and	and	CC
cord-017161-lcqrd4v0	141	6	occurrence	occurrence	NN
cord-017161-lcqrd4v0	141	7	of	of	IN
cord-017161-lcqrd4v0	141	8	epidemics	epidemic	NNS
cord-017161-lcqrd4v0	141	9	suggest	suggest	VBP
cord-017161-lcqrd4v0	141	10	an	an	DT
cord-017161-lcqrd4v0	141	11	infectious	infectious	JJ
cord-017161-lcqrd4v0	141	12	cause	cause	NN
cord-017161-lcqrd4v0	141	13	for	for	IN
cord-017161-lcqrd4v0	141	14	KD	KD	NNP
cord-017161-lcqrd4v0	141	15	,	,	,
cord-017161-lcqrd4v0	141	16	a	a	DT
cord-017161-lcqrd4v0	141	17	genetic	genetic	JJ
cord-017161-lcqrd4v0	141	18	contribution	contribution	NN
cord-017161-lcqrd4v0	141	19	to	to	IN
cord-017161-lcqrd4v0	141	20	risk	risk	NN
cord-017161-lcqrd4v0	141	21	is	be	VBZ
cord-017161-lcqrd4v0	141	22	suggested	suggest	VBN
cord-017161-lcqrd4v0	141	23	by	by	IN
cord-017161-lcqrd4v0	141	24	the	the	DT
cord-017161-lcqrd4v0	141	25	much	much	RB
cord-017161-lcqrd4v0	141	26	higher	high	JJR
cord-017161-lcqrd4v0	141	27	prevalence	prevalence	NN
cord-017161-lcqrd4v0	141	28	of	of	IN
cord-017161-lcqrd4v0	141	29	the	the	DT
cord-017161-lcqrd4v0	141	30	disease	disease	NN
cord-017161-lcqrd4v0	141	31	in	in	IN
cord-017161-lcqrd4v0	141	32	Japan	Japan	NNP
cord-017161-lcqrd4v0	141	33	and	and	CC
cord-017161-lcqrd4v0	141	34	Korea	Korea	NNP
cord-017161-lcqrd4v0	141	35	than	than	IN
cord-017161-lcqrd4v0	141	36	elsewhere	elsewhere	RB
cord-017161-lcqrd4v0	141	37	,	,	,
cord-017161-lcqrd4v0	141	38	and	and	CC
cord-017161-lcqrd4v0	141	39	by	by	IN
cord-017161-lcqrd4v0	141	40	increased	increase	VBN
cord-017161-lcqrd4v0	141	41	prevalence	prevalence	NN
cord-017161-lcqrd4v0	141	42	within	within	IN
cord-017161-lcqrd4v0	141	43	families	family	NNS
cord-017161-lcqrd4v0	141	44	with	with	IN
cord-017161-lcqrd4v0	141	45	an	an	DT
cord-017161-lcqrd4v0	141	46	increased	increase	VBN
cord-017161-lcqrd4v0	141	47	relative	relative	JJ
cord-017161-lcqrd4v0	141	48	risk	risk	NN
cord-017161-lcqrd4v0	141	49	to	to	IN
cord-017161-lcqrd4v0	141	50	siblings	sibling	NNS
cord-017161-lcqrd4v0	141	51	compared	compare	VBN
cord-017161-lcqrd4v0	141	52	to	to	IN
cord-017161-lcqrd4v0	141	53	the	the	DT
cord-017161-lcqrd4v0	141	54	general	general	JJ
cord-017161-lcqrd4v0	141	55	population	population	NN
cord-017161-lcqrd4v0	141	56	[	[	-LRB-
cord-017161-lcqrd4v0	141	57	75	75	CD
cord-017161-lcqrd4v0	141	58	]	]	-RRB-
cord-017161-lcqrd4v0	141	59	.	.	.
cord-017161-lcqrd4v0	142	1	Recently	recently	RB
cord-017161-lcqrd4v0	142	2	,	,	,
cord-017161-lcqrd4v0	142	3	a	a	DT
cord-017161-lcqrd4v0	142	4	number	number	NN
cord-017161-lcqrd4v0	142	5	of	of	IN
cord-017161-lcqrd4v0	142	6	polymorphisms	polymorphism	NNS
cord-017161-lcqrd4v0	142	7	have	have	VBP
cord-017161-lcqrd4v0	142	8	been	be	VBN
cord-017161-lcqrd4v0	142	9	identi	identi	FW
cord-017161-lcqrd4v0	142	10	fi	fi	NN
cord-017161-lcqrd4v0	142	11	ed	ed	NN
cord-017161-lcqrd4v0	142	12	that	that	WDT
cord-017161-lcqrd4v0	142	13	appear	appear	VBP
cord-017161-lcqrd4v0	142	14	to	to	TO
cord-017161-lcqrd4v0	142	15	be	be	VB
cord-017161-lcqrd4v0	142	16	linked	link	VBN
cord-017161-lcqrd4v0	142	17	with	with	IN
cord-017161-lcqrd4v0	142	18	disease	disease	NN
cord-017161-lcqrd4v0	142	19	susceptibility	susceptibility	NN
cord-017161-lcqrd4v0	142	20	in	in	IN
cord-017161-lcqrd4v0	142	21	KD	KD	NNP
cord-017161-lcqrd4v0	142	22	or	or	CC
cord-017161-lcqrd4v0	142	23	the	the	DT
cord-017161-lcqrd4v0	142	24	risk	risk	NN
cord-017161-lcqrd4v0	142	25	of	of	IN
cord-017161-lcqrd4v0	142	26	coronary	coronary	JJ
cord-017161-lcqrd4v0	142	27	artery	artery	NN
cord-017161-lcqrd4v0	142	28	aneurysms	aneurysm	NNS
cord-017161-lcqrd4v0	142	29	(	(	-LRB-
cord-017161-lcqrd4v0	142	30	CAAs	CAAs	NNP
cord-017161-lcqrd4v0	142	31	)	)	-RRB-
cord-017161-lcqrd4v0	142	32	.	.	.
cord-017161-lcqrd4v0	143	1	These	these	DT
cord-017161-lcqrd4v0	143	2	polymorphisms	polymorphism	NNS
cord-017161-lcqrd4v0	143	3	are	be	VBP
cord-017161-lcqrd4v0	143	4	summarized	summarize	VBN
cord-017161-lcqrd4v0	143	5	in	in	IN
cord-017161-lcqrd4v0	143	6	Table	Table	NNP
cord-017161-lcqrd4v0	143	7	2	2	CD
cord-017161-lcqrd4v0	143	8	.2	.2	.
cord-017161-lcqrd4v0	144	1	[	[	-LRB-
cord-017161-lcqrd4v0	144	2	4	4	CD
cord-017161-lcqrd4v0	144	3	,	,	,
cord-017161-lcqrd4v0	144	4	81	81	CD
cord-017161-lcqrd4v0	144	5	]	]	-RRB-
cord-017161-lcqrd4v0	144	6	.	.	.
cord-017161-lcqrd4v0	145	1	In	in	IN
cord-017161-lcqrd4v0	145	2	general	general	JJ
cord-017161-lcqrd4v0	145	3	,	,	,
cord-017161-lcqrd4v0	145	4	candidate	candidate	NN
cord-017161-lcqrd4v0	145	5	gene	gene	NN
cord-017161-lcqrd4v0	145	6	studies	study	NNS
cord-017161-lcqrd4v0	145	7	in	in	IN
cord-017161-lcqrd4v0	145	8	KD	KD	NNP
cord-017161-lcqrd4v0	145	9	have	have	VBP
cord-017161-lcqrd4v0	145	10	been	be	VBN
cord-017161-lcqrd4v0	145	11	dif	dif	NNP
cord-017161-lcqrd4v0	145	12	fi	fi	NN
cord-017161-lcqrd4v0	145	13	cult	cult	NN
cord-017161-lcqrd4v0	145	14	to	to	TO
cord-017161-lcqrd4v0	145	15	interpret	interpret	VB
cord-017161-lcqrd4v0	145	16	,	,	,
cord-017161-lcqrd4v0	145	17	since	since	IN
cord-017161-lcqrd4v0	145	18	most	most	JJS
cord-017161-lcqrd4v0	145	19	fi	fi	NN
cord-017161-lcqrd4v0	145	20	ndings	nding	NNS
cord-017161-lcqrd4v0	145	21	have	have	VBP
cord-017161-lcqrd4v0	145	22	not	not	RB
cord-017161-lcqrd4v0	145	23	been	be	VBN
cord-017161-lcqrd4v0	145	24	replicated	replicate	VBN
cord-017161-lcqrd4v0	145	25	.	.	.
cord-017161-lcqrd4v0	146	1	Indeed	indeed	RB
cord-017161-lcqrd4v0	146	2	,	,	,
cord-017161-lcqrd4v0	146	3	con	con	NNP
cord-017161-lcqrd4v0	146	4	fl	fl	NNP
cord-017161-lcqrd4v0	146	5	icting	icting	NN
cord-017161-lcqrd4v0	146	6	results	result	NNS
cord-017161-lcqrd4v0	146	7	have	have	VBP
cord-017161-lcqrd4v0	146	8	been	be	VBN
cord-017161-lcqrd4v0	146	9	reported	report	VBN
cord-017161-lcqrd4v0	146	10	for	for	IN
cord-017161-lcqrd4v0	146	11	the	the	DT
cord-017161-lcqrd4v0	146	12	few	few	JJ
cord-017161-lcqrd4v0	146	13	genes	gene	NNS
cord-017161-lcqrd4v0	146	14	that	that	WDT
cord-017161-lcqrd4v0	146	15	have	have	VBP
cord-017161-lcqrd4v0	146	16	been	be	VBN
cord-017161-lcqrd4v0	146	17	evaluated	evaluate	VBN
cord-017161-lcqrd4v0	146	18	in	in	IN
cord-017161-lcqrd4v0	146	19	multiple	multiple	JJ
cord-017161-lcqrd4v0	146	20	cohorts	cohort	NNS
cord-017161-lcqrd4v0	146	21	.	.	.
cord-017161-lcqrd4v0	147	1	Furthermore	furthermore	RB
cord-017161-lcqrd4v0	147	2	,	,	,
cord-017161-lcqrd4v0	147	3	a	a	DT
cord-017161-lcqrd4v0	147	4	genome	genome	NN
cord-017161-lcqrd4v0	147	5	-	-	HYPH
cord-017161-lcqrd4v0	147	6	wide	wide	JJ
cord-017161-lcqrd4v0	147	7	linkage	linkage	NN
cord-017161-lcqrd4v0	147	8	study	study	NN
cord-017161-lcqrd4v0	147	9	using	use	VBG
cord-017161-lcqrd4v0	147	10	microsatellite	microsatellite	JJ
cord-017161-lcqrd4v0	147	11	markers	marker	NNS
cord-017161-lcqrd4v0	147	12	in	in	IN
cord-017161-lcqrd4v0	147	13	Japanese	japanese	JJ
cord-017161-lcqrd4v0	147	14	families	family	NNS
cord-017161-lcqrd4v0	148	1	identi	identi	NNP
cord-017161-lcqrd4v0	148	2	fi	fi	NNP
cord-017161-lcqrd4v0	148	3	ed	ed	NN
cord-017161-lcqrd4v0	149	1	a	a	DT
cord-017161-lcqrd4v0	149	2	number	number	NN
cord-017161-lcqrd4v0	149	3	of	of	IN
cord-017161-lcqrd4v0	149	4	potential	potential	JJ
cord-017161-lcqrd4v0	149	5	loci	locus	NNS
cord-017161-lcqrd4v0	149	6	[	[	-LRB-
cord-017161-lcqrd4v0	149	7	92	92	CD
cord-017161-lcqrd4v0	149	8	]	]	-RRB-
cord-017161-lcqrd4v0	149	9	.	.	.
cord-017161-lcqrd4v0	150	1	Finer	fine	JJR
cord-017161-lcqrd4v0	150	2	scale	scale	NN
cord-017161-lcqrd4v0	150	3	studies	study	NNS
cord-017161-lcqrd4v0	150	4	of	of	IN
cord-017161-lcqrd4v0	150	5	the	the	DT
cord-017161-lcqrd4v0	150	6	19q32.2	19q32.2	CD
cord-017161-lcqrd4v0	150	7	-	-	SYM
cord-017161-lcqrd4v0	150	8	32.3	32.3	CD
cord-017161-lcqrd4v0	150	9	region	region	NN
cord-017161-lcqrd4v0	150	10	led	lead	VBD
cord-017161-lcqrd4v0	150	11	to	to	IN
cord-017161-lcqrd4v0	150	12	identi	identi	NNP
cord-017161-lcqrd4v0	150	13	fi	fi	NNP
cord-017161-lcqrd4v0	150	14	cation	cation	NNP
cord-017161-lcqrd4v0	150	15	of	of	IN
cord-017161-lcqrd4v0	150	16	a	a	DT
cord-017161-lcqrd4v0	150	17	linked	link	VBN
cord-017161-lcqrd4v0	150	18	group	group	NN
cord-017161-lcqrd4v0	150	19	of	of	IN
cord-017161-lcqrd4v0	150	20	single	single	JJ
cord-017161-lcqrd4v0	150	21	-	-	HYPH
cord-017161-lcqrd4v0	150	22	nucleotide	nucleotide	NN
cord-017161-lcqrd4v0	150	23	polymorphisms	polymorphism	NNS
cord-017161-lcqrd4v0	150	24	(	(	-LRB-
cord-017161-lcqrd4v0	150	25	SNPs	SNPs	NNP
cord-017161-lcqrd4v0	150	26	)	)	-RRB-
cord-017161-lcqrd4v0	150	27	in	in	IN
cord-017161-lcqrd4v0	150	28	the	the	DT
cord-017161-lcqrd4v0	150	29	inositol	inositol	NN
cord-017161-lcqrd4v0	150	30	1,4,5-trisphosphate	1,4,5-trisphosphate	CD
cord-017161-lcqrd4v0	150	31	3-kinase	3-kinase	CD
cord-017161-lcqrd4v0	150	32	C	C	NNP
cord-017161-lcqrd4v0	150	33	(	(	-LRB-
cord-017161-lcqrd4v0	150	34	ITPKC	ITPKC	NNP
cord-017161-lcqrd4v0	150	35	)	)	-RRB-
cord-017161-lcqrd4v0	150	36	gene	gene	NN
cord-017161-lcqrd4v0	150	37	,	,	,
cord-017161-lcqrd4v0	150	38	associated	associate	VBN
cord-017161-lcqrd4v0	150	39	with	with	IN
cord-017161-lcqrd4v0	150	40	KD	KD	NNP
cord-017161-lcqrd4v0	150	41	,	,	,
cord-017161-lcqrd4v0	150	42	with	with	IN
cord-017161-lcqrd4v0	150	43	an	an	DT
cord-017161-lcqrd4v0	150	44	odds	odd	NNS
cord-017161-lcqrd4v0	150	45	ratio	ratio	NN
cord-017161-lcqrd4v0	150	46	of	of	IN
cord-017161-lcqrd4v0	150	47	1.74	1.74	CD
cord-017161-lcqrd4v0	150	48	[	[	-LRB-
cord-017161-lcqrd4v0	150	49	75	75	CD
cord-017161-lcqrd4v0	150	50	,	,	,
cord-017161-lcqrd4v0	150	51	92	92	CD
cord-017161-lcqrd4v0	150	52	]	]	-RRB-
cord-017161-lcqrd4v0	150	53	.	.	.
cord-017161-lcqrd4v0	151	1	ITPKC	ITPKC	NNP
cord-017161-lcqrd4v0	151	2	mutation	mutation	NN
cord-017161-lcqrd4v0	151	3	was	be	VBD
cord-017161-lcqrd4v0	151	4	associated	associate	VBN
cord-017161-lcqrd4v0	151	5	with	with	IN
cord-017161-lcqrd4v0	151	6	KD	KD	NNP
cord-017161-lcqrd4v0	151	7	not	not	RB
cord-017161-lcqrd4v0	151	8	only	only	RB
cord-017161-lcqrd4v0	151	9	in	in	IN
cord-017161-lcqrd4v0	151	10	Japanese	Japanese	NNPS
cord-017161-lcqrd4v0	151	11	but	but	CC
cord-017161-lcqrd4v0	151	12	also	also	RB
cord-017161-lcqrd4v0	151	13	in	in	IN
cord-017161-lcqrd4v0	151	14	US	US	NNP
cord-017161-lcqrd4v0	151	15	Caucasian	caucasian	JJ
cord-017161-lcqrd4v0	151	16	patients	patient	NNS
cord-017161-lcqrd4v0	151	17	,	,	,
cord-017161-lcqrd4v0	151	18	particularly	particularly	RB
cord-017161-lcqrd4v0	151	19	with	with	IN
cord-017161-lcqrd4v0	151	20	the	the	DT
cord-017161-lcqrd4v0	151	21	risk	risk	NN
cord-017161-lcqrd4v0	151	22	for	for	IN
cord-017161-lcqrd4v0	151	23	developing	develop	VBG
cord-017161-lcqrd4v0	151	24	coronary	coronary	JJ
cord-017161-lcqrd4v0	151	25	artery	artery	NN
cord-017161-lcqrd4v0	151	26	lesions	lesion	NNS
cord-017161-lcqrd4v0	151	27	[	[	-LRB-
cord-017161-lcqrd4v0	151	28	75	75	CD
cord-017161-lcqrd4v0	151	29	,	,	,
cord-017161-lcqrd4v0	151	30	92	92	CD
cord-017161-lcqrd4v0	151	31	]	]	-RRB-
cord-017161-lcqrd4v0	151	32	.	.	.
cord-017161-lcqrd4v0	152	1	Additional	additional	JJ
cord-017161-lcqrd4v0	152	2	data	datum	NNS
cord-017161-lcqrd4v0	152	3	TNF	TNF	NNP
cord-017161-lcqrd4v0	152	4	-	-	:
cord-017161-lcqrd4v0	152	5	a	a	DT
cord-017161-lcqrd4v0	152	6	-308A	-308a	NN
cord-017161-lcqrd4v0	152	7	associated	associate	VBN
cord-017161-lcqrd4v0	152	8	with	with	IN
cord-017161-lcqrd4v0	152	9	increased	increase	VBN
cord-017161-lcqrd4v0	152	10	intravenous	intravenous	JJ
cord-017161-lcqrd4v0	152	11	immune	immune	JJ
cord-017161-lcqrd4v0	152	12	globulin	globulin	NN
cord-017161-lcqrd4v0	152	13	(	(	-LRB-
cord-017161-lcqrd4v0	152	14	IVIG	IVIG	NNP
cord-017161-lcqrd4v0	152	15	)	)	-RRB-
cord-017161-lcqrd4v0	152	16	resistance	resistance	NN
cord-017161-lcqrd4v0	152	17	[	[	-LRB-
cord-017161-lcqrd4v0	152	18	82	82	CD
cord-017161-lcqrd4v0	152	19	]	]	-RRB-
cord-017161-lcqrd4v0	152	20	Interleukin-10	interleukin-10	NN
cord-017161-lcqrd4v0	152	21	(	(	-LRB-
cord-017161-lcqrd4v0	152	22	IL10	IL10	NNP
cord-017161-lcqrd4v0	152	23	)	)	-RRB-
cord-017161-lcqrd4v0	152	24	IL-10	IL-10	NNP
cord-017161-lcqrd4v0	152	25	gene	gene	NN
cord-017161-lcqrd4v0	152	26	promoter	promoter	NN
cord-017161-lcqrd4v0	152	27	polymorphisms	polymorphism	NNS
cord-017161-lcqrd4v0	152	28	in	in	IN
cord-017161-lcqrd4v0	152	29	fl	fl	NNP
cord-017161-lcqrd4v0	152	30	uence	uence	NN
cord-017161-lcqrd4v0	152	31	risk	risk	NN
cord-017161-lcqrd4v0	152	32	of	of	IN
cord-017161-lcqrd4v0	152	33	CAA	CAA	NNP
cord-017161-lcqrd4v0	152	34	[	[	-LRB-
cord-017161-lcqrd4v0	152	35	82	82	CD
cord-017161-lcqrd4v0	152	36	]	]	-RRB-
cord-017161-lcqrd4v0	152	37	Vascular	vascular	JJ
cord-017161-lcqrd4v0	152	38	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	152	39	growth	growth	NN
cord-017161-lcqrd4v0	152	40	factor	factor	NN
cord-017161-lcqrd4v0	152	41	(	(	-LRB-
cord-017161-lcqrd4v0	152	42	VEGF	VEGF	NNP
cord-017161-lcqrd4v0	152	43	)	)	-RRB-
cord-017161-lcqrd4v0	152	44	and	and	CC
cord-017161-lcqrd4v0	152	45	its	-PRON-	PRP$
cord-017161-lcqrd4v0	152	46	receptor	receptor	NN
cord-017161-lcqrd4v0	152	47	(	(	-LRB-
cord-017161-lcqrd4v0	152	48	KDR	KDR	NNP
cord-017161-lcqrd4v0	152	49	)	)	-RRB-
cord-017161-lcqrd4v0	153	1	Polymorphisms	polymorphism	NNS
cord-017161-lcqrd4v0	153	2	of	of	IN
cord-017161-lcqrd4v0	153	3	both	both	DT
cord-017161-lcqrd4v0	153	4	contribute	contribute	VBP
cord-017161-lcqrd4v0	153	5	to	to	IN
cord-017161-lcqrd4v0	153	6	increased	increase	VBN
cord-017161-lcqrd4v0	153	7	CAA	CAA	NNP
cord-017161-lcqrd4v0	153	8	risk	risk	NN
cord-017161-lcqrd4v0	153	9	[	[	-LRB-
cord-017161-lcqrd4v0	153	10	83	83	CD
cord-017161-lcqrd4v0	153	11	]	]	-RRB-
cord-017161-lcqrd4v0	154	1	Chemokines	Chemokines	NNPS
cord-017161-lcqrd4v0	154	2	Chemokine	Chemokine	NNP
cord-017161-lcqrd4v0	154	3	receptor	receptor	NN
cord-017161-lcqrd4v0	154	4	CCR5	CCR5	NNP
cord-017161-lcqrd4v0	154	5	and	and	CC
cord-017161-lcqrd4v0	155	1	its	-PRON-	PRP$
cord-017161-lcqrd4v0	155	2	ligand	ligand	NN
cord-017161-lcqrd4v0	155	3	CCL3L1	CCL3L1	NNP
cord-017161-lcqrd4v0	155	4	in	in	IN
cord-017161-lcqrd4v0	155	5	fl	fl	NNP
cord-017161-lcqrd4v0	155	6	uence	uence	NN
cord-017161-lcqrd4v0	155	7	disease	disease	NN
cord-017161-lcqrd4v0	155	8	susceptibility	susceptibility	NN
cord-017161-lcqrd4v0	156	1	[	[	-LRB-
cord-017161-lcqrd4v0	156	2	84	84	CD
cord-017161-lcqrd4v0	156	3	]	]	-RRB-
cord-017161-lcqrd4v0	156	4	Nitric	nitric	NN
cord-017161-lcqrd4v0	156	5	oxide	oxide	NN
cord-017161-lcqrd4v0	156	6	and	and	CC
cord-017161-lcqrd4v0	156	7	associated	associate	VBD
cord-017161-lcqrd4v0	156	8	molecules	molecule	NNS
cord-017161-lcqrd4v0	156	9	Increased	increase	VBD
cord-017161-lcqrd4v0	156	10	risk	risk	NN
cord-017161-lcqrd4v0	156	11	of	of	IN
cord-017161-lcqrd4v0	156	12	CAA	CAA	NNP
cord-017161-lcqrd4v0	156	13	[	[	-LRB-
cord-017161-lcqrd4v0	156	14	91	91	CD
cord-017161-lcqrd4v0	156	15	]	]	-RRB-
cord-017161-lcqrd4v0	156	16	supported	support	VBD
cord-017161-lcqrd4v0	156	17	a	a	DT
cord-017161-lcqrd4v0	156	18	functional	functional	JJ
cord-017161-lcqrd4v0	156	19	signi	signi	NN
cord-017161-lcqrd4v0	156	20	fi	fi	NN
cord-017161-lcqrd4v0	156	21	cance	cance	NN
cord-017161-lcqrd4v0	156	22	for	for	IN
cord-017161-lcqrd4v0	156	23	one	one	CD
cord-017161-lcqrd4v0	156	24	polymorphism	polymorphism	NN
cord-017161-lcqrd4v0	156	25	identi	identi	FW
cord-017161-lcqrd4v0	156	26	fi	fi	NN
cord-017161-lcqrd4v0	156	27	ed	ed	NN
cord-017161-lcqrd4v0	156	28	:	:	:
cord-017161-lcqrd4v0	156	29	SNP	SNP	NNP
cord-017161-lcqrd4v0	156	30	(	(	-LRB-
cord-017161-lcqrd4v0	156	31	itpkc_3C	itpkc_3C	NNP
cord-017161-lcqrd4v0	156	32	)	)	-RRB-
cord-017161-lcqrd4v0	156	33	led	lead	VBD
cord-017161-lcqrd4v0	156	34	to	to	IN
cord-017161-lcqrd4v0	156	35	reduced	reduce	VBN
cord-017161-lcqrd4v0	156	36	splicing	splicing	NN
cord-017161-lcqrd4v0	156	37	of	of	IN
cord-017161-lcqrd4v0	156	38	the	the	DT
cord-017161-lcqrd4v0	156	39	ITPKC	ITPKC	NNP
cord-017161-lcqrd4v0	156	40	gene	gene	NN
cord-017161-lcqrd4v0	156	41	product	product	NN
cord-017161-lcqrd4v0	156	42	and	and	CC
cord-017161-lcqrd4v0	156	43	therefore	therefore	RB
cord-017161-lcqrd4v0	156	44	could	could	MD
cord-017161-lcqrd4v0	156	45	result	result	VB
cord-017161-lcqrd4v0	156	46	in	in	IN
cord-017161-lcqrd4v0	156	47	a	a	DT
cord-017161-lcqrd4v0	156	48	lower	low	JJR
cord-017161-lcqrd4v0	156	49	mRNA	mrna	NN
cord-017161-lcqrd4v0	156	50	concentration	concentration	NN
cord-017161-lcqrd4v0	156	51	[	[	-LRB-
cord-017161-lcqrd4v0	156	52	75	75	CD
cord-017161-lcqrd4v0	156	53	]	]	-RRB-
cord-017161-lcqrd4v0	156	54	.	.	.
cord-017161-lcqrd4v0	157	1	Of	of	IN
cord-017161-lcqrd4v0	157	2	note	note	NN
cord-017161-lcqrd4v0	157	3	,	,	,
cord-017161-lcqrd4v0	157	4	however	however	RB
cord-017161-lcqrd4v0	157	5	,	,	,
cord-017161-lcqrd4v0	157	6	Chi	Chi	NNP
cord-017161-lcqrd4v0	157	7	et	et	NNP
cord-017161-lcqrd4v0	157	8	al	al	NNP
cord-017161-lcqrd4v0	157	9	.	.	.
cord-017161-lcqrd4v0	158	1	subsequently	subsequently	RB
cord-017161-lcqrd4v0	158	2	showed	show	VBD
cord-017161-lcqrd4v0	158	3	no	no	DT
cord-017161-lcqrd4v0	158	4	statistically	statistically	RB
cord-017161-lcqrd4v0	158	5	signi	signi	JJ
cord-017161-lcqrd4v0	158	6	fi	fi	NN
cord-017161-lcqrd4v0	158	7	ca	can	MD
cord-017161-lcqrd4v0	158	8	nt	not	RB
cord-017161-lcqrd4v0	158	9	association	association	NN
cord-017161-lcqrd4v0	158	10	between	between	IN
cord-017161-lcqrd4v0	158	11	the	the	DT
cord-017161-lcqrd4v0	158	12	ITPKC	ITPKC	NNP
cord-017161-lcqrd4v0	158	13	gene	gene	NN
cord-017161-lcqrd4v0	158	14	SNP	SNP	NNP
cord-017161-lcqrd4v0	158	15	rs28493229	rs28493229	NNP
cord-017161-lcqrd4v0	158	16	and	and	CC
cord-017161-lcqrd4v0	158	17	KD	KD	NNP
cord-017161-lcqrd4v0	158	18	or	or	CC
cord-017161-lcqrd4v0	158	19	coronary	coronary	JJ
cord-017161-lcqrd4v0	158	20	artery	artery	NN
cord-017161-lcqrd4v0	158	21	lesions	lesion	NNS
cord-017161-lcqrd4v0	158	22	in	in	IN
cord-017161-lcqrd4v0	158	23	Taiwanese	taiwanese	JJ
cord-017161-lcqrd4v0	158	24	children	child	NNS
cord-017161-lcqrd4v0	158	25	[	[	-LRB-
cord-017161-lcqrd4v0	158	26	87	87	CD
cord-017161-lcqrd4v0	158	27	]	]	-RRB-
cord-017161-lcqrd4v0	158	28	.	.	.
cord-017161-lcqrd4v0	159	1	The	the	DT
cord-017161-lcqrd4v0	159	2	fi	fi	FW
cord-017161-lcqrd4v0	159	3	rst	rst	NNP
cord-017161-lcqrd4v0	159	4	genomewide	genomewide	NNP
cord-017161-lcqrd4v0	159	5	association	association	NNP
cord-017161-lcqrd4v0	159	6	study	study	NN
cord-017161-lcqrd4v0	159	7	(	(	-LRB-
cord-017161-lcqrd4v0	159	8	GWAS	GWAS	NNP
cord-017161-lcqrd4v0	159	9	)	)	-RRB-
cord-017161-lcqrd4v0	159	10	in	in	IN
cord-017161-lcqrd4v0	159	11	KD	KD	NNP
cord-017161-lcqrd4v0	159	12	was	be	VBD
cord-017161-lcqrd4v0	159	13	notable	notable	JJ
cord-017161-lcqrd4v0	159	14	for	for	IN
cord-017161-lcqrd4v0	159	15	assessment	assessment	NN
cord-017161-lcqrd4v0	159	16	of	of	IN
cord-017161-lcqrd4v0	159	17	population	population	NN
cord-017161-lcqrd4v0	159	18	strati	strati	NNP
cord-017161-lcqrd4v0	159	19	fi	fi	NNP
cord-017161-lcqrd4v0	159	20	cation	cation	NNP
cord-017161-lcqrd4v0	159	21	and	and	CC
cord-017161-lcqrd4v0	159	22	for	for	IN
cord-017161-lcqrd4v0	159	23	replication	replication	NN
cord-017161-lcqrd4v0	159	24	of	of	IN
cord-017161-lcqrd4v0	159	25	GWAS	GWAS	NNP
cord-017161-lcqrd4v0	159	26	fi	fi	NN
cord-017161-lcqrd4v0	159	27	ndings	nding	NNS
cord-017161-lcqrd4v0	159	28	in	in	IN
cord-017161-lcqrd4v0	159	29	an	an	DT
cord-017161-lcqrd4v0	159	30	independent	independent	JJ
cord-017161-lcqrd4v0	159	31	cohort	cohort	NN
cord-017161-lcqrd4v0	159	32	[	[	-LRB-
cord-017161-lcqrd4v0	159	33	93	93	CD
cord-017161-lcqrd4v0	159	34	]	]	-RRB-
cord-017161-lcqrd4v0	159	35	.	.	.
cord-017161-lcqrd4v0	160	1	GWAS	GWAS	NNP
cord-017161-lcqrd4v0	160	2	of	of	IN
cord-017161-lcqrd4v0	160	3	109	109	CD
cord-017161-lcqrd4v0	160	4	Caucasian	caucasian	JJ
cord-017161-lcqrd4v0	160	5	patients	patient	NNS
cord-017161-lcqrd4v0	160	6	,	,	,
cord-017161-lcqrd4v0	160	7	followed	follow	VBN
cord-017161-lcqrd4v0	160	8	by	by	IN
cord-017161-lcqrd4v0	160	9	SNP	SNP	NNP
cord-017161-lcqrd4v0	160	10	genotyping	genotyping	NN
cord-017161-lcqrd4v0	160	11	of	of	IN
cord-017161-lcqrd4v0	160	12	the	the	DT
cord-017161-lcqrd4v0	160	13	1,116	1,116	CD
cord-017161-lcqrd4v0	160	14	most	most	JJS
cord-017161-lcqrd4v0	160	15	signi	signi	NNP
cord-017161-lcqrd4v0	160	16	fi	fi	NN
cord-017161-lcqrd4v0	160	17	ca	can	MD
cord-017161-lcqrd4v0	160	18	nt	not	RB
cord-017161-lcqrd4v0	160	19	SNPs	SNPs	NNPS
cord-017161-lcqrd4v0	160	20	in	in	IN
cord-017161-lcqrd4v0	160	21	583	583	CD
cord-017161-lcqrd4v0	160	22	families	family	NNS
cord-017161-lcqrd4v0	160	23	,	,	,
cord-017161-lcqrd4v0	160	24	then	then	RB
cord-017161-lcqrd4v0	160	25	fi	fi	NNP
cord-017161-lcqrd4v0	160	26	ne	ne	NNP
cord-017161-lcqrd4v0	160	27	mapping	mapping	NN
cord-017161-lcqrd4v0	160	28	of	of	IN
cord-017161-lcqrd4v0	160	29	known	know	VBN
cord-017161-lcqrd4v0	160	30	genes	gene	NNS
cord-017161-lcqrd4v0	160	31	near	near	IN
cord-017161-lcqrd4v0	160	32	some	some	DT
cord-017161-lcqrd4v0	160	33	of	of	IN
cord-017161-lcqrd4v0	160	34	the	the	DT
cord-017161-lcqrd4v0	160	35	40	40	CD
cord-017161-lcqrd4v0	160	36	SNPs	SNPs	NNPS
cord-017161-lcqrd4v0	160	37	that	that	WDT
cord-017161-lcqrd4v0	160	38	were	be	VBD
cord-017161-lcqrd4v0	160	39	successfully	successfully	RB
cord-017161-lcqrd4v0	160	40	replicated	replicate	VBN
cord-017161-lcqrd4v0	160	41	,	,	,
cord-017161-lcqrd4v0	160	42	led	lead	VBD
cord-017161-lcqrd4v0	160	43	to	to	IN
cord-017161-lcqrd4v0	160	44	identi	identi	NNP
cord-017161-lcqrd4v0	160	45	fi	fi	NNP
cord-017161-lcqrd4v0	160	46	cation	cation	NNP
cord-017161-lcqrd4v0	160	47	of	of	IN
cord-017161-lcqrd4v0	160	48	eight	eight	CD
cord-017161-lcqrd4v0	160	49	putative	putative	JJ
cord-017161-lcqrd4v0	160	50	novel	novel	JJ
cord-017161-lcqrd4v0	160	51	susceptibility	susceptibility	NN
cord-017161-lcqrd4v0	160	52	genes	gene	NNS
cord-017161-lcqrd4v0	160	53	[	[	-LRB-
cord-017161-lcqrd4v0	160	54	odds	odd	NNS
cord-017161-lcqrd4v0	160	55	ratio	ratio	NN
cord-017161-lcqrd4v0	160	56	(	(	-LRB-
cord-017161-lcqrd4v0	160	57	OR	or	CC
cord-017161-lcqrd4v0	160	58	)	)	-RRB-
cord-017161-lcqrd4v0	160	59	approximately	approximately	RB
cord-017161-lcqrd4v0	160	60	1.1	1.1	CD
cord-017161-lcqrd4v0	160	61	-	-	SYM
cord-017161-lcqrd4v0	160	62	1.5	1.5	CD
cord-017161-lcqrd4v0	160	63	]	]	-RRB-
cord-017161-lcqrd4v0	160	64	[	[	-LRB-
cord-017161-lcqrd4v0	160	65	93	93	CD
cord-017161-lcqrd4v0	160	66	]	]	-RRB-
cord-017161-lcqrd4v0	160	67	.	.	.
cord-017161-lcqrd4v0	161	1	The	the	DT
cord-017161-lcqrd4v0	161	2	principal	principal	JJ
cord-017161-lcqrd4v0	161	3	clinical	clinical	JJ
cord-017161-lcqrd4v0	161	4	features	feature	NNS
cord-017161-lcqrd4v0	161	5	are	be	VBP
cord-017161-lcqrd4v0	161	6	fever	fever	NN
cord-017161-lcqrd4v0	161	7	persisting	persist	VBG
cord-017161-lcqrd4v0	161	8	for	for	IN
cord-017161-lcqrd4v0	161	9	5	5	CD
cord-017161-lcqrd4v0	161	10	days	day	NNS
cord-017161-lcqrd4v0	161	11	or	or	CC
cord-017161-lcqrd4v0	161	12	more	more	JJR
cord-017161-lcqrd4v0	161	13	,	,	,
cord-017161-lcqrd4v0	161	14	peripheral	peripheral	JJ
cord-017161-lcqrd4v0	161	15	extremity	extremity	NN
cord-017161-lcqrd4v0	161	16	changes	change	NNS
cord-017161-lcqrd4v0	161	17	(	(	-LRB-
cord-017161-lcqrd4v0	161	18	reddening	redden	VBG
cord-017161-lcqrd4v0	161	19	of	of	IN
cord-017161-lcqrd4v0	161	20	the	the	DT
cord-017161-lcqrd4v0	161	21	palms	palm	NNS
cord-017161-lcqrd4v0	161	22	and	and	CC
cord-017161-lcqrd4v0	161	23	soles	sol	NNS
cord-017161-lcqrd4v0	161	24	,	,	,
cord-017161-lcqrd4v0	161	25	indurative	indurative	JJ
cord-017161-lcqrd4v0	161	26	oedema	oedema	NN
cord-017161-lcqrd4v0	161	27	and	and	CC
cord-017161-lcqrd4v0	161	28	subsequent	subsequent	JJ
cord-017161-lcqrd4v0	161	29	desquamation	desquamation	NN
cord-017161-lcqrd4v0	161	30	)	)	-RRB-
cord-017161-lcqrd4v0	161	31	,	,	,
cord-017161-lcqrd4v0	161	32	a	a	DT
cord-017161-lcqrd4v0	161	33	polymorphous	polymorphous	JJ
cord-017161-lcqrd4v0	161	34	exanthema	exanthema	NN
cord-017161-lcqrd4v0	161	35	,	,	,
cord-017161-lcqrd4v0	161	36	bilateral	bilateral	JJ
cord-017161-lcqrd4v0	161	37	conjunctival	conjunctival	NN
cord-017161-lcqrd4v0	161	38	injection/	injection/	ADD
cord-017161-lcqrd4v0	161	39	congestion	congestion	NN
cord-017161-lcqrd4v0	161	40	,	,	,
cord-017161-lcqrd4v0	161	41	lips	lip	NNS
cord-017161-lcqrd4v0	161	42	and	and	CC
cord-017161-lcqrd4v0	161	43	oral	oral	JJ
cord-017161-lcqrd4v0	161	44	cavity	cavity	NN
cord-017161-lcqrd4v0	161	45	changes	change	NNS
cord-017161-lcqrd4v0	161	46	(	(	-LRB-
cord-017161-lcqrd4v0	161	47	reddening	redden	VBG
cord-017161-lcqrd4v0	161	48	/	/	SYM
cord-017161-lcqrd4v0	161	49	cracking	cracking	NN
cord-017161-lcqrd4v0	161	50	of	of	IN
cord-017161-lcqrd4v0	161	51	lips	lip	NNS
cord-017161-lcqrd4v0	161	52	,	,	,
cord-017161-lcqrd4v0	161	53	strawberry	strawberry	JJ
cord-017161-lcqrd4v0	161	54	tongue	tongue	NN
cord-017161-lcqrd4v0	161	55	,	,	,
cord-017161-lcqrd4v0	161	56	oral	oral	JJ
cord-017161-lcqrd4v0	161	57	and	and	CC
cord-017161-lcqrd4v0	161	58	pharyngeal	pharyngeal	JJ
cord-017161-lcqrd4v0	161	59	injection	injection	NN
cord-017161-lcqrd4v0	161	60	)	)	-RRB-
cord-017161-lcqrd4v0	161	61	and	and	CC
cord-017161-lcqrd4v0	161	62	cervical	cervical	JJ
cord-017161-lcqrd4v0	161	63	lymphadenopathy	lymphadenopathy	NN
cord-017161-lcqrd4v0	161	64	(	(	-LRB-
cord-017161-lcqrd4v0	161	65	acute	acute	JJ
cord-017161-lcqrd4v0	161	66	,	,	,
cord-017161-lcqrd4v0	161	67	nonpurulent	nonpurulent	NN
cord-017161-lcqrd4v0	161	68	)	)	-RRB-
cord-017161-lcqrd4v0	162	1	[	[	-LRB-
cord-017161-lcqrd4v0	162	2	56	56	CD
cord-017161-lcqrd4v0	162	3	]	]	-RRB-
cord-017161-lcqrd4v0	162	4	.	.	.
cord-017161-lcqrd4v0	163	1	For	for	IN
cord-017161-lcqrd4v0	163	2	the	the	DT
cord-017161-lcqrd4v0	163	3	diagnosis	diagnosis	NN
cord-017161-lcqrd4v0	163	4	to	to	TO
cord-017161-lcqrd4v0	163	5	be	be	VB
cord-017161-lcqrd4v0	163	6	established	establish	VBN
cord-017161-lcqrd4v0	163	7	according	accord	VBG
cord-017161-lcqrd4v0	163	8	to	to	IN
cord-017161-lcqrd4v0	163	9	the	the	DT
cord-017161-lcqrd4v0	163	10	Diagnostic	Diagnostic	NNP
cord-017161-lcqrd4v0	163	11	Guidelines	Guidelines	NNPS
cord-017161-lcqrd4v0	163	12	of	of	IN
cord-017161-lcqrd4v0	163	13	the	the	DT
cord-017161-lcqrd4v0	163	14	Japan	Japan	NNP
cord-017161-lcqrd4v0	163	15	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	163	16	Disease	Disease	NNP
cord-017161-lcqrd4v0	163	17	Research	Research	NNP
cord-017161-lcqrd4v0	163	18	Committee	Committee	NNP
cord-017161-lcqrd4v0	163	19	,	,	,
cord-017161-lcqrd4v0	163	20	fi	fi	NNP
cord-017161-lcqrd4v0	163	21	ve	ve	VBD
cord-017161-lcqrd4v0	163	22	of	of	IN
cord-017161-lcqrd4v0	163	23	six	six	CD
cord-017161-lcqrd4v0	163	24	criteria	criterion	NNS
cord-017161-lcqrd4v0	163	25	should	should	MD
cord-017161-lcqrd4v0	163	26	be	be	VB
cord-017161-lcqrd4v0	163	27	present	present	JJ
cord-017161-lcqrd4v0	163	28	[	[	-LRB-
cord-017161-lcqrd4v0	163	29	94	94	CD
cord-017161-lcqrd4v0	163	30	]	]	-RRB-
cord-017161-lcqrd4v0	163	31	.	.	.
cord-017161-lcqrd4v0	164	1	If	if	IN
cord-017161-lcqrd4v0	164	2	CAAs	caa	NNS
cord-017161-lcqrd4v0	164	3	are	be	VBP
cord-017161-lcqrd4v0	164	4	present	present	JJ
cord-017161-lcqrd4v0	164	5	,	,	,
cord-017161-lcqrd4v0	164	6	fewer	few	JJR
cord-017161-lcqrd4v0	164	7	features	feature	NNS
cord-017161-lcqrd4v0	164	8	may	may	MD
cord-017161-lcqrd4v0	164	9	be	be	VB
cord-017161-lcqrd4v0	164	10	necessary	necessary	JJ
cord-017161-lcqrd4v0	164	11	for	for	IN
cord-017161-lcqrd4v0	164	12	diagnostic	diagnostic	JJ
cord-017161-lcqrd4v0	164	13	purposes	purpose	NNS
cord-017161-lcqrd4v0	164	14	[	[	-LRB-
cord-017161-lcqrd4v0	164	15	48	48	CD
cord-017161-lcqrd4v0	164	16	,	,	,
cord-017161-lcqrd4v0	164	17	95	95	CD
cord-017161-lcqrd4v0	164	18	]	]	-RRB-
cord-017161-lcqrd4v0	164	19	.	.	.
cord-017161-lcqrd4v0	165	1	The	the	DT
cord-017161-lcqrd4v0	165	2	cardiovascular	cardiovascular	JJ
cord-017161-lcqrd4v0	165	3	features	feature	NNS
cord-017161-lcqrd4v0	165	4	are	be	VBP
cord-017161-lcqrd4v0	165	5	the	the	DT
cord-017161-lcqrd4v0	165	6	most	most	RBS
cord-017161-lcqrd4v0	165	7	important	important	JJ
cord-017161-lcqrd4v0	165	8	manifestations	manifestation	NNS
cord-017161-lcqrd4v0	165	9	of	of	IN
cord-017161-lcqrd4v0	165	10	the	the	DT
cord-017161-lcqrd4v0	165	11	condition	condition	NN
cord-017161-lcqrd4v0	165	12	with	with	IN
cord-017161-lcqrd4v0	165	13	widespread	widespread	JJ
cord-017161-lcqrd4v0	165	14	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	165	15	affecting	affect	VBG
cord-017161-lcqrd4v0	165	16	predominantly	predominantly	RB
cord-017161-lcqrd4v0	165	17	medium	medium	JJ
cord-017161-lcqrd4v0	165	18	-	-	HYPH
cord-017161-lcqrd4v0	165	19	size	size	NN
cord-017161-lcqrd4v0	165	20	muscular	muscular	JJ
cord-017161-lcqrd4v0	165	21	arteries	artery	NNS
cord-017161-lcqrd4v0	165	22	,	,	,
cord-017161-lcqrd4v0	165	23	especially	especially	RB
cord-017161-lcqrd4v0	165	24	the	the	DT
cord-017161-lcqrd4v0	165	25	coronary	coronary	JJ
cord-017161-lcqrd4v0	165	26	arteries	artery	NNS
cord-017161-lcqrd4v0	165	27	[	[	-LRB-
cord-017161-lcqrd4v0	165	28	56	56	CD
cord-017161-lcqrd4v0	165	29	]	]	-RRB-
cord-017161-lcqrd4v0	165	30	.	.	.
cord-017161-lcqrd4v0	166	1	Coronary	coronary	JJ
cord-017161-lcqrd4v0	166	2	artery	artery	NN
cord-017161-lcqrd4v0	166	3	involvement	involvement	NN
cord-017161-lcqrd4v0	166	4	occurs	occur	VBZ
cord-017161-lcqrd4v0	166	5	in	in	IN
cord-017161-lcqrd4v0	166	6	15	15	CD
cord-017161-lcqrd4v0	166	7	-	-	SYM
cord-017161-lcqrd4v0	166	8	25	25	CD
cord-017161-lcqrd4v0	166	9	%	%	NN
cord-017161-lcqrd4v0	166	10	of	of	IN
cord-017161-lcqrd4v0	166	11	untreated	untreated	JJ
cord-017161-lcqrd4v0	166	12	cases	case	NNS
cord-017161-lcqrd4v0	166	13	with	with	IN
cord-017161-lcqrd4v0	166	14	additional	additional	JJ
cord-017161-lcqrd4v0	166	15	cardiac	cardiac	JJ
cord-017161-lcqrd4v0	166	16	features	feature	NNS
cord-017161-lcqrd4v0	166	17	in	in	IN
cord-017161-lcqrd4v0	166	18	a	a	DT
cord-017161-lcqrd4v0	166	19	signi	signi	NN
cord-017161-lcqrd4v0	166	20	fi	fi	NN
cord-017161-lcqrd4v0	167	1	ca	can	MD
cord-017161-lcqrd4v0	167	2	nt	not	RB
cord-017161-lcqrd4v0	167	3	proportion	proportion	NN
cord-017161-lcqrd4v0	167	4	of	of	IN
cord-017161-lcqrd4v0	167	5	these	these	DT
cord-017161-lcqrd4v0	167	6	,	,	,
cord-017161-lcqrd4v0	167	7	including	include	VBG
cord-017161-lcqrd4v0	167	8	pericardial	pericardial	JJ
cord-017161-lcqrd4v0	167	9	effusion	effusion	NN
cord-017161-lcqrd4v0	167	10	,	,	,
cord-017161-lcqrd4v0	167	11	electrocardiographic	electrocardiographic	JJ
cord-017161-lcqrd4v0	167	12	abnormalities	abnormality	NNS
cord-017161-lcqrd4v0	167	13	,	,	,
cord-017161-lcqrd4v0	167	14	pericarditis	pericarditis	NN
cord-017161-lcqrd4v0	167	15	,	,	,
cord-017161-lcqrd4v0	167	16	myocarditis	myocarditis	NN
cord-017161-lcqrd4v0	167	17	,	,	,
cord-017161-lcqrd4v0	167	18	valvular	valvular	JJ
cord-017161-lcqrd4v0	167	19	incompetence	incompetence	NN
cord-017161-lcqrd4v0	167	20	,	,	,
cord-017161-lcqrd4v0	167	21	cardiac	cardiac	JJ
cord-017161-lcqrd4v0	167	22	failure	failure	NN
cord-017161-lcqrd4v0	167	23	and	and	CC
cord-017161-lcqrd4v0	167	24	myocardial	myocardial	JJ
cord-017161-lcqrd4v0	167	25	infarction	infarction	NN
cord-017161-lcqrd4v0	167	26	[	[	-LRB-
cord-017161-lcqrd4v0	167	27	56	56	CD
cord-017161-lcqrd4v0	167	28	]	]	-RRB-
cord-017161-lcqrd4v0	167	29	.	.	.
cord-017161-lcqrd4v0	168	1	Another	another	DT
cord-017161-lcqrd4v0	168	2	clinical	clinical	JJ
cord-017161-lcqrd4v0	168	3	sign	sign	NN
cord-017161-lcqrd4v0	168	4	that	that	IN
cord-017161-lcqrd4v0	168	5	maybe	maybe	RB
cord-017161-lcqrd4v0	168	6	relatively	relatively	RB
cord-017161-lcqrd4v0	168	7	speci	speci	XX
cord-017161-lcqrd4v0	168	8	fi	fi	NN
cord-017161-lcqrd4v0	168	9	c	c	NN
cord-017161-lcqrd4v0	168	10	to	to	IN
cord-017161-lcqrd4v0	168	11	KD	KD	NNP
cord-017161-lcqrd4v0	168	12	is	be	VBZ
cord-017161-lcqrd4v0	168	13	the	the	DT
cord-017161-lcqrd4v0	168	14	development	development	NN
cord-017161-lcqrd4v0	168	15	of	of	IN
cord-017161-lcqrd4v0	168	16	erythema	erythema	NN
cord-017161-lcqrd4v0	168	17	and	and	CC
cord-017161-lcqrd4v0	168	18	induration	induration	NN
cord-017161-lcqrd4v0	168	19	at	at	IN
cord-017161-lcqrd4v0	168	20	sites	site	NNS
cord-017161-lcqrd4v0	168	21	of	of	IN
cord-017161-lcqrd4v0	168	22	Bacille	Bacille	NNP
cord-017161-lcqrd4v0	168	23	Calmette	Calmette	NNP
cord-017161-lcqrd4v0	168	24	-	-	HYPH
cord-017161-lcqrd4v0	168	25	Guérin	Guérin	NNP
cord-017161-lcqrd4v0	168	26	(	(	-LRB-
cord-017161-lcqrd4v0	168	27	BCG	BCG	NNP
cord-017161-lcqrd4v0	168	28	)	)	-RRB-
cord-017161-lcqrd4v0	168	29	inoculations	inoculation	NNS
cord-017161-lcqrd4v0	168	30	[	[	-LRB-
cord-017161-lcqrd4v0	168	31	46	46	CD
cord-017161-lcqrd4v0	168	32	]	]	-RRB-
cord-017161-lcqrd4v0	168	33	.	.	.
cord-017161-lcqrd4v0	169	1	Other	other	JJ
cord-017161-lcqrd4v0	169	2	system	system	NN
cord-017161-lcqrd4v0	169	3	involvement	involvement	NN
cord-017161-lcqrd4v0	169	4	can	can	MD
cord-017161-lcqrd4v0	169	5	occur	occur	VB
cord-017161-lcqrd4v0	169	6	,	,	,
cord-017161-lcqrd4v0	169	7	including	include	VBG
cord-017161-lcqrd4v0	169	8	the	the	DT
cord-017161-lcqrd4v0	169	9	gastrointestinal	gastrointestinal	JJ
cord-017161-lcqrd4v0	169	10	tract	tract	NN
cord-017161-lcqrd4v0	169	11	,	,	,
cord-017161-lcqrd4v0	169	12	the	the	DT
cord-017161-lcqrd4v0	169	13	hepatobiliary	hepatobiliary	JJ
cord-017161-lcqrd4v0	169	14	tract	tract	NN
cord-017161-lcqrd4v0	169	15	with	with	IN
cord-017161-lcqrd4v0	169	16	hydrops	hydrop	NNS
cord-017161-lcqrd4v0	169	17	of	of	IN
cord-017161-lcqrd4v0	169	18	the	the	DT
cord-017161-lcqrd4v0	169	19	gall	gall	NN
cord-017161-lcqrd4v0	169	20	bladder	bladder	NN
cord-017161-lcqrd4v0	169	21	being	be	VBG
cord-017161-lcqrd4v0	169	22	well	well	RB
cord-017161-lcqrd4v0	169	23	recognised	recognise	VBN
cord-017161-lcqrd4v0	169	24	,	,	,
cord-017161-lcqrd4v0	169	25	the	the	DT
cord-017161-lcqrd4v0	169	26	central	central	JJ
cord-017161-lcqrd4v0	169	27	nervous	nervous	JJ
cord-017161-lcqrd4v0	169	28	system	system	NN
cord-017161-lcqrd4v0	169	29	with	with	IN
cord-017161-lcqrd4v0	169	30	seizure	seizure	NN
cord-017161-lcqrd4v0	169	31	and	and	CC
cord-017161-lcqrd4v0	169	32	meningeal	meningeal	NN
cord-017161-lcqrd4v0	169	33	features	feature	NNS
cord-017161-lcqrd4v0	169	34	,	,	,
cord-017161-lcqrd4v0	169	35	the	the	DT
cord-017161-lcqrd4v0	169	36	auditory	auditory	JJ
cord-017161-lcqrd4v0	169	37	system	system	NN
cord-017161-lcqrd4v0	169	38	with	with	IN
cord-017161-lcqrd4v0	169	39	deafness	deafness	NN
cord-017161-lcqrd4v0	169	40	,	,	,
cord-017161-lcqrd4v0	169	41	the	the	DT
cord-017161-lcqrd4v0	169	42	skeletal	skeletal	JJ
cord-017161-lcqrd4v0	169	43	system	system	NN
cord-017161-lcqrd4v0	169	44	with	with	IN
cord-017161-lcqrd4v0	169	45	arthropathy	arthropathy	NNP
cord-017161-lcqrd4v0	169	46	and	and	CC
cord-017161-lcqrd4v0	169	47	the	the	DT
cord-017161-lcqrd4v0	169	48	urinary	urinary	JJ
cord-017161-lcqrd4v0	169	49	system	system	NN
cord-017161-lcqrd4v0	169	50	[	[	-LRB-
cord-017161-lcqrd4v0	169	51	56	56	CD
cord-017161-lcqrd4v0	169	52	]	]	-RRB-
cord-017161-lcqrd4v0	169	53	.	.	.
cord-017161-lcqrd4v0	170	1	Early	early	JJ
cord-017161-lcqrd4v0	170	2	recognition	recognition	NN
cord-017161-lcqrd4v0	170	3	and	and	CC
cord-017161-lcqrd4v0	170	4	treatment	treatment	NN
cord-017161-lcqrd4v0	170	5	of	of	IN
cord-017161-lcqrd4v0	170	6	KD	KD	NNP
cord-017161-lcqrd4v0	170	7	with	with	IN
cord-017161-lcqrd4v0	170	8	aspirin	aspirin	NN
cord-017161-lcqrd4v0	170	9	and	and	CC
cord-017161-lcqrd4v0	170	10	IVIG	IVIG	NNP
cord-017161-lcqrd4v0	170	11	have	have	VBP
cord-017161-lcqrd4v0	170	12	been	be	VBN
cord-017161-lcqrd4v0	170	13	shown	show	VBN
cord-017161-lcqrd4v0	170	14	unequivocally	unequivocally	RB
cord-017161-lcqrd4v0	170	15	by	by	IN
cord-017161-lcqrd4v0	170	16	meta	meta	NNP
cord-017161-lcqrd4v0	170	17	-	-	HYPH
cord-017161-lcqrd4v0	170	18	analysis	analysis	NN
cord-017161-lcqrd4v0	170	19	to	to	TO
cord-017161-lcqrd4v0	170	20	reduce	reduce	VB
cord-017161-lcqrd4v0	170	21	the	the	DT
cord-017161-lcqrd4v0	170	22	occurrence	occurrence	NN
cord-017161-lcqrd4v0	170	23	of	of	IN
cord-017161-lcqrd4v0	170	24	CAAs	CAAs	NNP
cord-017161-lcqrd4v0	170	25	[	[	-LRB-
cord-017161-lcqrd4v0	170	26	96	96	CD
cord-017161-lcqrd4v0	170	27	,	,	,
cord-017161-lcqrd4v0	170	28	97	97	CD
cord-017161-lcqrd4v0	170	29	]	]	-RRB-
cord-017161-lcqrd4v0	170	30	.	.	.
cord-017161-lcqrd4v0	171	1	The	the	DT
cord-017161-lcqrd4v0	171	2	prevalence	prevalence	NN
cord-017161-lcqrd4v0	171	3	of	of	IN
cord-017161-lcqrd4v0	171	4	CAA	CAA	NNP
cord-017161-lcqrd4v0	171	5	is	be	VBZ
cord-017161-lcqrd4v0	171	6	inversely	inversely	RB
cord-017161-lcqrd4v0	171	7	related	relate	VBN
cord-017161-lcqrd4v0	171	8	to	to	IN
cord-017161-lcqrd4v0	171	9	the	the	DT
cord-017161-lcqrd4v0	171	10	total	total	JJ
cord-017161-lcqrd4v0	171	11	dose	dose	NN
cord-017161-lcqrd4v0	171	12	of	of	IN
cord-017161-lcqrd4v0	171	13	IVIG	IVIG	NNP
cord-017161-lcqrd4v0	171	14	[	[	-LRB-
cord-017161-lcqrd4v0	171	15	97	97	CD
cord-017161-lcqrd4v0	171	16	]	]	-RRB-
cord-017161-lcqrd4v0	171	17	,	,	,
cord-017161-lcqrd4v0	171	18	2	2	CD
cord-017161-lcqrd4v0	171	19	g	g	NN
cord-017161-lcqrd4v0	171	20	/	/	SYM
cord-017161-lcqrd4v0	171	21	kg	kg	NN
cord-017161-lcqrd4v0	171	22	of	of	IN
cord-017161-lcqrd4v0	171	23	IVIG	IVIG	NNP
cord-017161-lcqrd4v0	171	24	being	be	VBG
cord-017161-lcqrd4v0	171	25	the	the	DT
cord-017161-lcqrd4v0	171	26	optimal	optimal	JJ
cord-017161-lcqrd4v0	171	27	dose	dose	NN
cord-017161-lcqrd4v0	171	28	,	,	,
cord-017161-lcqrd4v0	171	29	usually	usually	RB
cord-017161-lcqrd4v0	171	30	given	give	VBN
cord-017161-lcqrd4v0	171	31	as	as	IN
cord-017161-lcqrd4v0	171	32	a	a	DT
cord-017161-lcqrd4v0	171	33	single	single	JJ
cord-017161-lcqrd4v0	171	34	infusion	infusion	NN
cord-017161-lcqrd4v0	171	35	[	[	-LRB-
cord-017161-lcqrd4v0	171	36	96	96	CD
cord-017161-lcqrd4v0	171	37	]	]	-RRB-
cord-017161-lcqrd4v0	171	38	.	.	.
cord-017161-lcqrd4v0	172	1	Meta	Meta	NNP
cord-017161-lcqrd4v0	172	2	-	-	HYPH
cord-017161-lcqrd4v0	172	3	analysis	analysis	NN
cord-017161-lcqrd4v0	172	4	of	of	IN
cord-017161-lcqrd4v0	172	5	RCTs	RCTs	NNP
cord-017161-lcqrd4v0	172	6	comparing	compare	VBG
cord-017161-lcqrd4v0	172	7	divided	divide	VBN
cord-017161-lcqrd4v0	172	8	lower	low	JJR
cord-017161-lcqrd4v0	172	9	doses	dose	NNS
cord-017161-lcqrd4v0	172	10	of	of	IN
cord-017161-lcqrd4v0	172	11	IVIG	IVIG	NNP
cord-017161-lcqrd4v0	172	12	(	(	-LRB-
cord-017161-lcqrd4v0	172	13	400	400	CD
cord-017161-lcqrd4v0	172	14	mg	mg	NNP
cord-017161-lcqrd4v0	172	15	/	/	SYM
cord-017161-lcqrd4v0	172	16	kg	kg	NNP
cord-017161-lcqrd4v0	172	17	/	/	SYM
cord-017161-lcqrd4v0	172	18	day	day	NN
cord-017161-lcqrd4v0	172	19	for	for	IN
cord-017161-lcqrd4v0	172	20	4	4	CD
cord-017161-lcqrd4v0	172	21	consecutive	consecutive	JJ
cord-017161-lcqrd4v0	172	22	days	day	NNS
cord-017161-lcqrd4v0	172	23	)	)	-RRB-
cord-017161-lcqrd4v0	172	24	versus	versus	IN
cord-017161-lcqrd4v0	172	25	a	a	DT
cord-017161-lcqrd4v0	172	26	single	single	JJ
cord-017161-lcqrd4v0	172	27	infusion	infusion	NN
cord-017161-lcqrd4v0	172	28	of	of	IN
cord-017161-lcqrd4v0	172	29	high	high	JJ
cord-017161-lcqrd4v0	172	30	-	-	HYPH
cord-017161-lcqrd4v0	172	31	dose	dose	NN
cord-017161-lcqrd4v0	172	32	IVIG	IVIG	NNP
cord-017161-lcqrd4v0	172	33	(	(	-LRB-
cord-017161-lcqrd4v0	172	34	2	2	CD
cord-017161-lcqrd4v0	172	35	g	g	NN
cord-017161-lcqrd4v0	172	36	/	/	SYM
cord-017161-lcqrd4v0	172	37	kg	kg	NN
cord-017161-lcqrd4v0	172	38	over	over	IN
cord-017161-lcqrd4v0	172	39	10	10	CD
cord-017161-lcqrd4v0	172	40	h	h	NN
cord-017161-lcqrd4v0	172	41	)	)	-RRB-
cord-017161-lcqrd4v0	172	42	has	have	VBZ
cord-017161-lcqrd4v0	172	43	clearly	clearly	RB
cord-017161-lcqrd4v0	172	44	shown	show	VBN
cord-017161-lcqrd4v0	172	45	that	that	IN
cord-017161-lcqrd4v0	172	46	even	even	RB
cord-017161-lcqrd4v0	172	47	though	though	IN
cord-017161-lcqrd4v0	172	48	the	the	DT
cord-017161-lcqrd4v0	172	49	4-day	4-day	JJ
cord-017161-lcqrd4v0	172	50	regimen	regimen	NN
cord-017161-lcqrd4v0	172	51	has	have	VBZ
cord-017161-lcqrd4v0	172	52	some	some	DT
cord-017161-lcqrd4v0	172	53	bene	bene	NN
cord-017161-lcqrd4v0	172	54	fi	fi	NN
cord-017161-lcqrd4v0	172	55	t	t	NN
cord-017161-lcqrd4v0	172	56	,	,	,
cord-017161-lcqrd4v0	172	57	a	a	DT
cord-017161-lcqrd4v0	172	58	single	single	JJ
cord-017161-lcqrd4v0	172	59	dose	dose	NN
cord-017161-lcqrd4v0	172	60	of	of	IN
cord-017161-lcqrd4v0	172	61	2	2	CD
cord-017161-lcqrd4v0	172	62	g	g	NN
cord-017161-lcqrd4v0	172	63	/	/	SYM
cord-017161-lcqrd4v0	172	64	kg	kg	NNP
cord-017161-lcqrd4v0	172	65	has	have	VBZ
cord-017161-lcqrd4v0	172	66	a	a	DT
cord-017161-lcqrd4v0	172	67	greater	great	JJR
cord-017161-lcqrd4v0	172	68	therapeutic	therapeutic	JJ
cord-017161-lcqrd4v0	172	69	effect	effect	NN
cord-017161-lcqrd4v0	172	70	in	in	IN
cord-017161-lcqrd4v0	172	71	the	the	DT
cord-017161-lcqrd4v0	172	72	prevention	prevention	NN
cord-017161-lcqrd4v0	172	73	of	of	IN
cord-017161-lcqrd4v0	172	74	CAA	CAA	NNP
cord-017161-lcqrd4v0	172	75	[	[	-LRB-
cord-017161-lcqrd4v0	172	76	96	96	CD
cord-017161-lcqrd4v0	172	77	,	,	,
cord-017161-lcqrd4v0	172	78	97	97	CD
cord-017161-lcqrd4v0	172	79	]	]	-RRB-
cord-017161-lcqrd4v0	172	80	.	.	.
cord-017161-lcqrd4v0	173	1	However	however	RB
cord-017161-lcqrd4v0	173	2	,	,	,
cord-017161-lcqrd4v0	173	3	IVIG	IVIG	NNP
cord-017161-lcqrd4v0	173	4	resistance	resistance	NN
cord-017161-lcqrd4v0	173	5	occurs	occur	VBZ
cord-017161-lcqrd4v0	173	6	in	in	IN
cord-017161-lcqrd4v0	173	7	up	up	IN
cord-017161-lcqrd4v0	173	8	to	to	TO
cord-017161-lcqrd4v0	173	9	20	20	CD
cord-017161-lcqrd4v0	173	10	%	%	NN
cord-017161-lcqrd4v0	173	11	of	of	IN
cord-017161-lcqrd4v0	173	12	cases	case	NNS
cord-017161-lcqrd4v0	173	13	[	[	-LRB-
cord-017161-lcqrd4v0	173	14	98	98	CD
cord-017161-lcqrd4v0	173	15	]	]	-RRB-
cord-017161-lcqrd4v0	173	16	.	.	.
cord-017161-lcqrd4v0	174	1	In	in	IN
cord-017161-lcqrd4v0	174	2	those	those	DT
cord-017161-lcqrd4v0	174	3	cases	case	NNS
cord-017161-lcqrd4v0	174	4	most	most	JJS
cord-017161-lcqrd4v0	174	5	advocate	advocate	VBP
cord-017161-lcqrd4v0	174	6	a	a	DT
cord-017161-lcqrd4v0	174	7	second	second	JJ
cord-017161-lcqrd4v0	174	8	dose	dose	NN
cord-017161-lcqrd4v0	174	9	of	of	IN
cord-017161-lcqrd4v0	174	10	IVIG	IVIG	NNP
cord-017161-lcqrd4v0	174	11	and/or	and/or	CC
cord-017161-lcqrd4v0	174	12	the	the	DT
cord-017161-lcqrd4v0	174	13	use	use	NN
cord-017161-lcqrd4v0	174	14	of	of	IN
cord-017161-lcqrd4v0	174	15	corticosteroids	corticosteroid	NNS
cord-017161-lcqrd4v0	174	16	.	.	.
cord-017161-lcqrd4v0	175	1	Regarding	regard	VBG
cord-017161-lcqrd4v0	175	2	corticosteroid	corticosteroid	NN
cord-017161-lcqrd4v0	175	3	use	use	NN
cord-017161-lcqrd4v0	175	4	in	in	IN
cord-017161-lcqrd4v0	175	5	IVIG	IVIG	NNP
cord-017161-lcqrd4v0	175	6	resistant	resistant	JJ
cord-017161-lcqrd4v0	175	7	to	to	IN
cord-017161-lcqrd4v0	175	8	KD	KD	NNP
cord-017161-lcqrd4v0	175	9	,	,	,
cord-017161-lcqrd4v0	175	10	there	there	EX
cord-017161-lcqrd4v0	175	11	are	be	VBP
cord-017161-lcqrd4v0	175	12	apparently	apparently	RB
cord-017161-lcqrd4v0	175	13	con	con	NNP
cord-017161-lcqrd4v0	175	14	fl	fl	NNP
cord-017161-lcqrd4v0	175	15	icting	icting	NN
cord-017161-lcqrd4v0	175	16	data	datum	NNS
cord-017161-lcqrd4v0	175	17	from	from	IN
cord-017161-lcqrd4v0	175	18	clinical	clinical	JJ
cord-017161-lcqrd4v0	175	19	trials	trial	NNS
cord-017161-lcqrd4v0	175	20	.	.	.
cord-017161-lcqrd4v0	176	1	Inoue	Inoue	NNP
cord-017161-lcqrd4v0	176	2	et	et	NNP
cord-017161-lcqrd4v0	176	3	al	al	NNP
cord-017161-lcqrd4v0	176	4	.	.	.
cord-017161-lcqrd4v0	177	1	reported	report	VBN
cord-017161-lcqrd4v0	177	2	on	on	IN
cord-017161-lcqrd4v0	177	3	a	a	DT
cord-017161-lcqrd4v0	177	4	randomized	randomized	JJ
cord-017161-lcqrd4v0	177	5	control	control	NN
cord-017161-lcqrd4v0	177	6	trial	trial	NN
cord-017161-lcqrd4v0	177	7	of	of	IN
cord-017161-lcqrd4v0	177	8	178	178	CD
cord-017161-lcqrd4v0	177	9	KD	KD	NNP
cord-017161-lcqrd4v0	177	10	patients	patient	NNS
cord-017161-lcqrd4v0	177	11	who	who	WP
cord-017161-lcqrd4v0	177	12	were	be	VBD
cord-017161-lcqrd4v0	177	13	assigned	assign	VBN
cord-017161-lcqrd4v0	177	14	to	to	TO
cord-017161-lcqrd4v0	177	15	receive	receive	VB
cord-017161-lcqrd4v0	177	16	IVIG	IVIG	NNP
cord-017161-lcqrd4v0	177	17	(	(	-LRB-
cord-017161-lcqrd4v0	177	18	1	1	CD
cord-017161-lcqrd4v0	177	19	g	g	NN
cord-017161-lcqrd4v0	177	20	/	/	SYM
cord-017161-lcqrd4v0	177	21	kg	kg	NNP
cord-017161-lcqrd4v0	177	22	/	/	SYM
cord-017161-lcqrd4v0	177	23	day	day	NN
cord-017161-lcqrd4v0	177	24	)	)	-RRB-
cord-017161-lcqrd4v0	177	25	for	for	IN
cord-017161-lcqrd4v0	177	26	two	two	CD
cord-017161-lcqrd4v0	177	27	consecutive	consecutive	JJ
cord-017161-lcqrd4v0	177	28	days	day	NNS
cord-017161-lcqrd4v0	177	29	,	,	,
cord-017161-lcqrd4v0	177	30	given	give	VBN
cord-017161-lcqrd4v0	177	31	over	over	IN
cord-017161-lcqrd4v0	177	32	12	12	CD
cord-017161-lcqrd4v0	177	33	h	h	NN
cord-017161-lcqrd4v0	177	34	,	,	,
cord-017161-lcqrd4v0	177	35	or	or	CC
cord-017161-lcqrd4v0	177	36	IVIG	IVIG	NNP
cord-017161-lcqrd4v0	177	37	plus	plus	CC
cord-017161-lcqrd4v0	177	38	prednisolone	prednisolone	NN
cord-017161-lcqrd4v0	177	39	sodium	sodium	NN
cord-017161-lcqrd4v0	177	40	succinate	succinate	NNP
cord-017161-lcqrd4v0	177	41	(	(	-LRB-
cord-017161-lcqrd4v0	177	42	2	2	CD
cord-017161-lcqrd4v0	177	43	mg	mg	NNP
cord-017161-lcqrd4v0	177	44	/	/	SYM
cord-017161-lcqrd4v0	177	45	kg	kg	NNP
cord-017161-lcqrd4v0	177	46	/	/	SYM
cord-017161-lcqrd4v0	177	47	day	day	NN
cord-017161-lcqrd4v0	177	48	)	)	-RRB-
cord-017161-lcqrd4v0	178	1	three	three	CD
cord-017161-lcqrd4v0	178	2	times	time	NNS
cord-017161-lcqrd4v0	178	3	daily	daily	RB
cord-017161-lcqrd4v0	178	4	,	,	,
cord-017161-lcqrd4v0	178	5	given	give	VBN
cord-017161-lcqrd4v0	178	6	by	by	IN
cord-017161-lcqrd4v0	178	7	intravenous	intravenous	JJ
cord-017161-lcqrd4v0	178	8	(	(	-LRB-
cord-017161-lcqrd4v0	178	9	IV	IV	NNP
cord-017161-lcqrd4v0	178	10	)	)	-RRB-
cord-017161-lcqrd4v0	178	11	injection	injection	NN
cord-017161-lcqrd4v0	178	12	until	until	IN
cord-017161-lcqrd4v0	178	13	the	the	DT
cord-017161-lcqrd4v0	178	14	fever	fever	NN
cord-017161-lcqrd4v0	178	15	resolved	resolve	VBN
cord-017161-lcqrd4v0	178	16	and	and	CC
cord-017161-lcqrd4v0	178	17	then	then	RB
cord-017161-lcqrd4v0	178	18	orally	orally	RB
cord-017161-lcqrd4v0	178	19	until	until	IN
cord-017161-lcqrd4v0	178	20	the	the	DT
cord-017161-lcqrd4v0	178	21	C	C	NNP
cord-017161-lcqrd4v0	178	22	-	-	HYPH
cord-017161-lcqrd4v0	178	23	reactive	reactive	JJ
cord-017161-lcqrd4v0	178	24	protein	protein	NN
cord-017161-lcqrd4v0	178	25	(	(	-LRB-
cord-017161-lcqrd4v0	178	26	CRP	CRP	NNP
cord-017161-lcqrd4v0	178	27	)	)	-RRB-
cord-017161-lcqrd4v0	178	28	level	level	NN
cord-017161-lcqrd4v0	178	29	normalized	normalize	VBD
cord-017161-lcqrd4v0	178	30	[	[	-LRB-
cord-017161-lcqrd4v0	178	31	98	98	CD
cord-017161-lcqrd4v0	178	32	]	]	-RRB-
cord-017161-lcqrd4v0	178	33	.	.	.
cord-017161-lcqrd4v0	179	1	Patients	patient	NNS
cord-017161-lcqrd4v0	179	2	in	in	IN
cord-017161-lcqrd4v0	179	3	both	both	DT
cord-017161-lcqrd4v0	179	4	groups	group	NNS
cord-017161-lcqrd4v0	179	5	received	receive	VBD
cord-017161-lcqrd4v0	179	6	aspirin	aspirin	NN
cord-017161-lcqrd4v0	179	7	(	(	-LRB-
cord-017161-lcqrd4v0	179	8	30	30	CD
cord-017161-lcqrd4v0	179	9	mg	mg	NN
cord-017161-lcqrd4v0	179	10	/	/	SYM
cord-017161-lcqrd4v0	179	11	kg	kg	NNP
cord-017161-lcqrd4v0	179	12	)	)	-RRB-
cord-017161-lcqrd4v0	179	13	and	and	CC
cord-017161-lcqrd4v0	179	14	dipyridamole	dipyridamole	NNP
cord-017161-lcqrd4v0	179	15	(	(	-LRB-
cord-017161-lcqrd4v0	179	16	2	2	CD
cord-017161-lcqrd4v0	179	17	mg	mg	NNP
cord-017161-lcqrd4v0	179	18	/	/	SYM
cord-017161-lcqrd4v0	179	19	kg	kg	NNP
cord-017161-lcqrd4v0	179	20	/	/	SYM
cord-017161-lcqrd4v0	179	21	day	day	NN
cord-017161-lcqrd4v0	179	22	)	)	-RRB-
cord-017161-lcqrd4v0	179	23	[	[	-LRB-
cord-017161-lcqrd4v0	179	24	98	98	CD
cord-017161-lcqrd4v0	179	25	]	]	-RRB-
cord-017161-lcqrd4v0	179	26	.	.	.
cord-017161-lcqrd4v0	180	1	The	the	DT
cord-017161-lcqrd4v0	180	2	addition	addition	NN
cord-017161-lcqrd4v0	180	3	of	of	IN
cord-017161-lcqrd4v0	180	4	corticosteroid	corticosteroid	NN
cord-017161-lcqrd4v0	180	5	was	be	VBD
cord-017161-lcqrd4v0	180	6	associated	associate	VBN
cord-017161-lcqrd4v0	180	7	with	with	IN
cord-017161-lcqrd4v0	180	8	reduced	reduce	VBN
cord-017161-lcqrd4v0	180	9	CAA	caa	NN
cord-017161-lcqrd4v0	180	10	compared	compare	VBN
cord-017161-lcqrd4v0	180	11	with	with	IN
cord-017161-lcqrd4v0	180	12	IVIG	IVIG	NNP
cord-017161-lcqrd4v0	180	13	alone	alone	RB
cord-017161-lcqrd4v0	180	14	:	:	:
cord-017161-lcqrd4v0	180	15	in	in	IN
cord-017161-lcqrd4v0	180	16	those	those	DT
cord-017161-lcqrd4v0	180	17	receiving	receive	VBG
cord-017161-lcqrd4v0	180	18	IVIG	IVIG	NNP
cord-017161-lcqrd4v0	180	19	and	and	CC
cord-017161-lcqrd4v0	180	20	anti	anti	JJ
cord-017161-lcqrd4v0	180	21	-	-	JJ
cord-017161-lcqrd4v0	180	22	platelet	platelet	JJ
cord-017161-lcqrd4v0	180	23	therapy	therapy	NN
cord-017161-lcqrd4v0	180	24	,	,	,
cord-017161-lcqrd4v0	180	25	11.4	11.4	CD
cord-017161-lcqrd4v0	180	26	%	%	NN
cord-017161-lcqrd4v0	180	27	had	have	VBD
cord-017161-lcqrd4v0	180	28	CAA	CAA	NNP
cord-017161-lcqrd4v0	180	29	at	at	IN
cord-017161-lcqrd4v0	180	30	1	1	CD
cord-017161-lcqrd4v0	180	31	month	month	NN
cord-017161-lcqrd4v0	180	32	,	,	,
cord-017161-lcqrd4v0	180	33	compared	compare	VBN
cord-017161-lcqrd4v0	180	34	with	with	IN
cord-017161-lcqrd4v0	180	35	2.2	2.2	CD
cord-017161-lcqrd4v0	180	36	%	%	NN
cord-017161-lcqrd4v0	180	37	in	in	IN
cord-017161-lcqrd4v0	180	38	those	those	DT
cord-017161-lcqrd4v0	180	39	receiving	receive	VBG
cord-017161-lcqrd4v0	180	40	IVIG	IVIG	NNP
cord-017161-lcqrd4v0	180	41	plus	plus	CC
cord-017161-lcqrd4v0	180	42	corticosteroids	corticosteroid	NNS
cord-017161-lcqrd4v0	180	43	[	[	-LRB-
cord-017161-lcqrd4v0	180	44	98	98	CD
cord-017161-lcqrd4v0	180	45	]	]	-RRB-
cord-017161-lcqrd4v0	180	46	.	.	.
cord-017161-lcqrd4v0	181	1	Also	also	RB
cord-017161-lcqrd4v0	181	2	the	the	DT
cord-017161-lcqrd4v0	181	3	duration	duration	NN
cord-017161-lcqrd4v0	181	4	of	of	IN
cord-017161-lcqrd4v0	181	5	fever	fever	NN
cord-017161-lcqrd4v0	181	6	was	be	VBD
cord-017161-lcqrd4v0	181	7	shorter	short	JJR
cord-017161-lcqrd4v0	181	8	and	and	CC
cord-017161-lcqrd4v0	181	9	CRP	CRP	NNP
cord-017161-lcqrd4v0	181	10	decreased	decrease	VBD
cord-017161-lcqrd4v0	181	11	more	more	RBR
cord-017161-lcqrd4v0	181	12	rapidly	rapidly	RB
cord-017161-lcqrd4v0	181	13	in	in	IN
cord-017161-lcqrd4v0	181	14	the	the	DT
cord-017161-lcqrd4v0	181	15	group	group	NN
cord-017161-lcqrd4v0	181	16	of	of	IN
cord-017161-lcqrd4v0	181	17	patients	patient	NNS
cord-017161-lcqrd4v0	181	18	receiving	receive	VBG
cord-017161-lcqrd4v0	181	19	corticosteroids	corticosteroid	NNS
cord-017161-lcqrd4v0	181	20	[	[	-LRB-
cord-017161-lcqrd4v0	181	21	98	98	CD
cord-017161-lcqrd4v0	181	22	]	]	-RRB-
cord-017161-lcqrd4v0	181	23	.	.	.
cord-017161-lcqrd4v0	182	1	In	in	IN
cord-017161-lcqrd4v0	182	2	contrast	contrast	NN
cord-017161-lcqrd4v0	182	3	,	,	,
cord-017161-lcqrd4v0	182	4	Newburger	Newburger	NNP
cord-017161-lcqrd4v0	182	5	et	et	NNP
cord-017161-lcqrd4v0	182	6	al	al	NNP
cord-017161-lcqrd4v0	182	7	.	.	.
cord-017161-lcqrd4v0	183	1	in	in	IN
cord-017161-lcqrd4v0	183	2	a	a	DT
cord-017161-lcqrd4v0	183	3	subsequent	subsequent	JJ
cord-017161-lcqrd4v0	183	4	multicenter	multicenter	NN
cord-017161-lcqrd4v0	183	5	,	,	,
cord-017161-lcqrd4v0	183	6	randomized	randomized	JJ
cord-017161-lcqrd4v0	183	7	,	,	,
cord-017161-lcqrd4v0	183	8	doubleblind	doubleblind	NN
cord-017161-lcqrd4v0	183	9	,	,	,
cord-017161-lcqrd4v0	183	10	placebo	placebo	NN
cord-017161-lcqrd4v0	183	11	-	-	HYPH
cord-017161-lcqrd4v0	183	12	controlled	control	VBN
cord-017161-lcqrd4v0	183	13	trial	trial	NN
cord-017161-lcqrd4v0	183	14	examined	examine	VBD
cord-017161-lcqrd4v0	183	15	the	the	DT
cord-017161-lcqrd4v0	183	16	effect	effect	NN
cord-017161-lcqrd4v0	183	17	of	of	IN
cord-017161-lcqrd4v0	183	18	the	the	DT
cord-017161-lcqrd4v0	183	19	addition	addition	NN
cord-017161-lcqrd4v0	183	20	of	of	IN
cord-017161-lcqrd4v0	183	21	a	a	DT
cord-017161-lcqrd4v0	183	22	single	single	JJ
cord-017161-lcqrd4v0	183	23	dose	dose	NN
cord-017161-lcqrd4v0	183	24	of	of	IN
cord-017161-lcqrd4v0	183	25	intravenous	intravenous	JJ
cord-017161-lcqrd4v0	183	26	methylprednisolone	methylprednisolone	NN
cord-017161-lcqrd4v0	183	27	to	to	IN
cord-017161-lcqrd4v0	183	28	standard	standard	JJ
cord-017161-lcqrd4v0	183	29	therapy	therapy	NN
cord-017161-lcqrd4v0	183	30	[	[	-LRB-
cord-017161-lcqrd4v0	183	31	99	99	CD
cord-017161-lcqrd4v0	183	32	]	]	-RRB-
cord-017161-lcqrd4v0	183	33	.	.	.
cord-017161-lcqrd4v0	184	1	They	-PRON-	PRP
cord-017161-lcqrd4v0	184	2	found	find	VBD
cord-017161-lcqrd4v0	184	3	that	that	IN
cord-017161-lcqrd4v0	184	4	this	this	DT
cord-017161-lcqrd4v0	184	5	corticosteroid	corticosteroid	NN
cord-017161-lcqrd4v0	184	6	regimen	regimen	NN
cord-017161-lcqrd4v0	184	7	did	do	VBD
cord-017161-lcqrd4v0	184	8	not	not	RB
cord-017161-lcqrd4v0	184	9	improve	improve	VB
cord-017161-lcqrd4v0	184	10	the	the	DT
cord-017161-lcqrd4v0	184	11	CAA	CAA	NNP
cord-017161-lcqrd4v0	184	12	outcome	outcome	NN
cord-017161-lcqrd4v0	184	13	in	in	IN
cord-017161-lcqrd4v0	184	14	these	these	DT
cord-017161-lcqrd4v0	184	15	children	child	NNS
cord-017161-lcqrd4v0	184	16	[	[	-LRB-
cord-017161-lcqrd4v0	184	17	99	99	CD
cord-017161-lcqrd4v0	184	18	]	]	-RRB-
cord-017161-lcqrd4v0	184	19	.	.	.
cord-017161-lcqrd4v0	185	1	These	these	DT
cord-017161-lcqrd4v0	185	2	contrasting	contrast	VBG
cord-017161-lcqrd4v0	185	3	results	result	NNS
cord-017161-lcqrd4v0	185	4	suggest	suggest	VBP
cord-017161-lcqrd4v0	185	5	that	that	IN
cord-017161-lcqrd4v0	185	6	dose	dose	NN
cord-017161-lcqrd4v0	185	7	and	and	CC
cord-017161-lcqrd4v0	185	8	duration	duration	NN
cord-017161-lcqrd4v0	185	9	of	of	IN
cord-017161-lcqrd4v0	185	10	corticosteroids	corticosteroid	NNS
cord-017161-lcqrd4v0	185	11	may	may	MD
cord-017161-lcqrd4v0	185	12	be	be	VB
cord-017161-lcqrd4v0	185	13	critical	critical	JJ
cord-017161-lcqrd4v0	185	14	when	when	WRB
cord-017161-lcqrd4v0	185	15	considering	consider	VBG
cord-017161-lcqrd4v0	185	16	this	this	DT
cord-017161-lcqrd4v0	185	17	as	as	IN
cord-017161-lcqrd4v0	185	18	adjunctive	adjunctive	JJ
cord-017161-lcqrd4v0	185	19	therapy	therapy	NN
cord-017161-lcqrd4v0	185	20	in	in	IN
cord-017161-lcqrd4v0	185	21	KD	KD	NNP
cord-017161-lcqrd4v0	185	22	.	.	.
cord-017161-lcqrd4v0	186	1	In	in	IN
cord-017161-lcqrd4v0	186	2	fl	fl	NNP
cord-017161-lcqrd4v0	186	3	iximab	iximab	NNS
cord-017161-lcqrd4v0	186	4	,	,	,
cord-017161-lcqrd4v0	186	5	a	a	DT
cord-017161-lcqrd4v0	186	6	chimeric	chimeric	JJ
cord-017161-lcqrd4v0	186	7	monoclonal	monoclonal	JJ
cord-017161-lcqrd4v0	186	8	antibody	antibody	NN
cord-017161-lcqrd4v0	186	9	against	against	IN
cord-017161-lcqrd4v0	186	10	TNF	TNF	NNP
cord-017161-lcqrd4v0	186	11	-	-	HYPH
cord-017161-lcqrd4v0	186	12	a	a	NNP
cord-017161-lcqrd4v0	186	13	,	,	,
cord-017161-lcqrd4v0	186	14	has	have	VBZ
cord-017161-lcqrd4v0	186	15	been	be	VBN
cord-017161-lcqrd4v0	186	16	reported	report	VBN
cord-017161-lcqrd4v0	186	17	to	to	TO
cord-017161-lcqrd4v0	186	18	be	be	VB
cord-017161-lcqrd4v0	186	19	effective	effective	JJ
cord-017161-lcqrd4v0	186	20	for	for	IN
cord-017161-lcqrd4v0	186	21	the	the	DT
cord-017161-lcqrd4v0	186	22	treatment	treatment	NN
cord-017161-lcqrd4v0	186	23	of	of	IN
cord-017161-lcqrd4v0	186	24	IVIG	IVIG	NNP
cord-017161-lcqrd4v0	186	25	-	-	HYPH
cord-017161-lcqrd4v0	186	26	resistant	resistant	JJ
cord-017161-lcqrd4v0	186	27	KD	KD	NNP
cord-017161-lcqrd4v0	186	28	[	[	-LRB-
cord-017161-lcqrd4v0	186	29	100	100	CD
cord-017161-lcqrd4v0	186	30	,	,	,
cord-017161-lcqrd4v0	186	31	101	101	CD
cord-017161-lcqrd4v0	186	32	]	]	-RRB-
cord-017161-lcqrd4v0	186	33	.	.	.
cord-017161-lcqrd4v0	187	1	In	in	IN
cord-017161-lcqrd4v0	187	2	13	13	CD
cord-017161-lcqrd4v0	187	3	of	of	IN
cord-017161-lcqrd4v0	187	4	16	16	CD
cord-017161-lcqrd4v0	187	5	patients	patient	NNS
cord-017161-lcqrd4v0	187	6	with	with	IN
cord-017161-lcqrd4v0	187	7	failed	failed	JJ
cord-017161-lcqrd4v0	187	8	response	response	NN
cord-017161-lcqrd4v0	187	9	to	to	IN
cord-017161-lcqrd4v0	187	10	a	a	DT
cord-017161-lcqrd4v0	187	11	single	single	JJ
cord-017161-lcqrd4v0	187	12	dose	dose	NN
cord-017161-lcqrd4v0	187	13	or	or	CC
cord-017161-lcqrd4v0	187	14	IVIG	IVIG	NNP
cord-017161-lcqrd4v0	187	15	who	who	WP
cord-017161-lcqrd4v0	187	16	received	receive	VBD
cord-017161-lcqrd4v0	187	17	in	in	IN
cord-017161-lcqrd4v0	187	18	fl	fl	NNP
cord-017161-lcqrd4v0	187	19	iximab	iximab	NNS
cord-017161-lcqrd4v0	187	20	,	,	,
cord-017161-lcqrd4v0	187	21	there	there	EX
cord-017161-lcqrd4v0	187	22	was	be	VBD
cord-017161-lcqrd4v0	187	23	cessation	cessation	NN
cord-017161-lcqrd4v0	187	24	of	of	IN
cord-017161-lcqrd4v0	187	25	fever	fever	NN
cord-017161-lcqrd4v0	187	26	followed	follow	VBN
cord-017161-lcqrd4v0	187	27	by	by	IN
cord-017161-lcqrd4v0	187	28	reduction	reduction	NN
cord-017161-lcqrd4v0	187	29	in	in	IN
cord-017161-lcqrd4v0	187	30	CRP	CRP	NNP
cord-017161-lcqrd4v0	187	31	[	[	-LRB-
cord-017161-lcqrd4v0	187	32	100	100	CD
cord-017161-lcqrd4v0	187	33	]	]	-RRB-
cord-017161-lcqrd4v0	187	34	.	.	.
cord-017161-lcqrd4v0	188	1	More	more	RBR
cord-017161-lcqrd4v0	188	2	recently	recently	RB
cord-017161-lcqrd4v0	188	3	,	,	,
cord-017161-lcqrd4v0	188	4	Burns	Burns	NNP
cord-017161-lcqrd4v0	188	5	et	et	NNP
cord-017161-lcqrd4v0	188	6	al	al	NNP
cord-017161-lcqrd4v0	188	7	.	.	NNP
cord-017161-lcqrd4v0	188	8	reported	report	VBD
cord-017161-lcqrd4v0	188	9	on	on	IN
cord-017161-lcqrd4v0	188	10	a	a	DT
cord-017161-lcqrd4v0	188	11	multi	multi	JJ
cord-017161-lcqrd4v0	188	12	-	-	JJ
cord-017161-lcqrd4v0	188	13	centre	centre	JJ
cord-017161-lcqrd4v0	188	14	,	,	,
cord-017161-lcqrd4v0	188	15	randomized	randomized	JJ
cord-017161-lcqrd4v0	188	16	,	,	,
cord-017161-lcqrd4v0	188	17	prospective	prospective	JJ
cord-017161-lcqrd4v0	188	18	trial	trial	NN
cord-017161-lcqrd4v0	188	19	of	of	IN
cord-017161-lcqrd4v0	188	20	second	second	JJ
cord-017161-lcqrd4v0	188	21	IVIG	IVIG	NNP
cord-017161-lcqrd4v0	188	22	infusion	infusion	NN
cord-017161-lcqrd4v0	188	23	(	(	-LRB-
cord-017161-lcqrd4v0	188	24	2	2	CD
cord-017161-lcqrd4v0	188	25	g	g	NN
cord-017161-lcqrd4v0	188	26	/	/	SYM
cord-017161-lcqrd4v0	188	27	kg	kg	NNP
cord-017161-lcqrd4v0	188	28	)	)	-RRB-
cord-017161-lcqrd4v0	188	29	versus	versus	IN
cord-017161-lcqrd4v0	188	30	in	in	IN
cord-017161-lcqrd4v0	188	31	fl	fl	NNP
cord-017161-lcqrd4v0	188	32	iximab	iximab	NNP
cord-017161-lcqrd4v0	188	33	(	(	-LRB-
cord-017161-lcqrd4v0	188	34	5	5	CD
cord-017161-lcqrd4v0	188	35	mg	mg	NNP
cord-017161-lcqrd4v0	188	36	/	/	SYM
cord-017161-lcqrd4v0	188	37	kg	kg	NNP
cord-017161-lcqrd4v0	188	38	)	)	-RRB-
cord-017161-lcqrd4v0	188	39	in	in	IN
cord-017161-lcqrd4v0	188	40	24	24	CD
cord-017161-lcqrd4v0	188	41	children	child	NNS
cord-017161-lcqrd4v0	188	42	with	with	IN
cord-017161-lcqrd4v0	188	43	acute	acute	JJ
cord-017161-lcqrd4v0	188	44	KD	kd	NN
cord-017161-lcqrd4v0	188	45	and	and	CC
cord-017161-lcqrd4v0	188	46	fever	fever	NN
cord-017161-lcqrd4v0	188	47	after	after	IN
cord-017161-lcqrd4v0	188	48	initial	initial	JJ
cord-017161-lcqrd4v0	188	49	failed	fail	VBN
cord-017161-lcqrd4v0	188	50	treatment	treatment	NN
cord-017161-lcqrd4v0	188	51	with	with	IN
cord-017161-lcqrd4v0	188	52	IVIG	IVIG	NNP
cord-017161-lcqrd4v0	188	53	[	[	-LRB-
cord-017161-lcqrd4v0	188	54	101	101	CD
cord-017161-lcqrd4v0	188	55	]	]	-RRB-
cord-017161-lcqrd4v0	188	56	.	.	.
cord-017161-lcqrd4v0	189	1	There	there	EX
cord-017161-lcqrd4v0	189	2	was	be	VBD
cord-017161-lcqrd4v0	189	3	cessation	cessation	NN
cord-017161-lcqrd4v0	189	4	of	of	IN
cord-017161-lcqrd4v0	189	5	fever	fever	NN
cord-017161-lcqrd4v0	189	6	within	within	IN
cord-017161-lcqrd4v0	189	7	24	24	CD
cord-017161-lcqrd4v0	189	8	h	h	NN
cord-017161-lcqrd4v0	189	9	in	in	IN
cord-017161-lcqrd4v0	189	10	11	11	CD
cord-017161-lcqrd4v0	189	11	of	of	IN
cord-017161-lcqrd4v0	189	12	12	12	CD
cord-017161-lcqrd4v0	189	13	subjects	subject	NNS
cord-017161-lcqrd4v0	189	14	treated	treat	VBN
cord-017161-lcqrd4v0	189	15	with	with	IN
cord-017161-lcqrd4v0	189	16	in	in	IN
cord-017161-lcqrd4v0	189	17	fl	fl	NNP
cord-017161-lcqrd4v0	189	18	iximab	iximab	NNS
cord-017161-lcqrd4v0	189	19	and	and	CC
cord-017161-lcqrd4v0	189	20	in	in	IN
cord-017161-lcqrd4v0	189	21	8	8	CD
cord-017161-lcqrd4v0	189	22	of	of	IN
cord-017161-lcqrd4v0	189	23	12	12	CD
cord-017161-lcqrd4v0	189	24	subjects	subject	NNS
cord-017161-lcqrd4v0	189	25	retreated	retreat	VBD
cord-017161-lcqrd4v0	189	26	with	with	IN
cord-017161-lcqrd4v0	189	27	IVIG	IVIG	NNP
cord-017161-lcqrd4v0	189	28	[	[	-LRB-
cord-017161-lcqrd4v0	189	29	101	101	CD
cord-017161-lcqrd4v0	189	30	]	]	-RRB-
cord-017161-lcqrd4v0	189	31	.	.	.
cord-017161-lcqrd4v0	190	1	No	no	DT
cord-017161-lcqrd4v0	190	2	signi	signi	NN
cord-017161-lcqrd4v0	190	3	fi	fi	NN
cord-017161-lcqrd4v0	191	1	ca	can	MD
cord-017161-lcqrd4v0	191	2	nt	not	RB
cord-017161-lcqrd4v0	191	3	differences	difference	NNS
cord-017161-lcqrd4v0	191	4	were	be	VBD
cord-017161-lcqrd4v0	191	5	observed	observe	VBN
cord-017161-lcqrd4v0	191	6	between	between	IN
cord-017161-lcqrd4v0	191	7	treatment	treatment	NN
cord-017161-lcqrd4v0	191	8	groups	group	NNS
cord-017161-lcqrd4v0	191	9	in	in	IN
cord-017161-lcqrd4v0	191	10	the	the	DT
cord-017161-lcqrd4v0	191	11	change	change	NN
cord-017161-lcqrd4v0	191	12	from	from	IN
cord-017161-lcqrd4v0	191	13	baseline	baseline	NN
cord-017161-lcqrd4v0	191	14	for	for	IN
cord-017161-lcqrd4v0	191	15	laboratory	laboratory	NN
cord-017161-lcqrd4v0	191	16	variables	variable	NNS
cord-017161-lcqrd4v0	191	17	,	,	,
cord-017161-lcqrd4v0	191	18	fever	fever	NN
cord-017161-lcqrd4v0	191	19	or	or	CC
cord-017161-lcqrd4v0	191	20	echocardiographic	echocardiographic	JJ
cord-017161-lcqrd4v0	191	21	assessment	assessment	NN
cord-017161-lcqrd4v0	191	22	of	of	IN
cord-017161-lcqrd4v0	191	23	coronary	coronary	JJ
cord-017161-lcqrd4v0	191	24	arteries	artery	NNS
cord-017161-lcqrd4v0	191	25	[	[	-LRB-
cord-017161-lcqrd4v0	191	26	101	101	CD
cord-017161-lcqrd4v0	191	27	]	]	-RRB-
cord-017161-lcqrd4v0	191	28	.	.	.
cord-017161-lcqrd4v0	192	1	These	these	DT
cord-017161-lcqrd4v0	192	2	reports	report	NNS
cord-017161-lcqrd4v0	192	3	are	be	VBP
cord-017161-lcqrd4v0	192	4	encouraging	encourage	VBG
cord-017161-lcqrd4v0	192	5	but	but	CC
cord-017161-lcqrd4v0	192	6	further	further	JJ
cord-017161-lcqrd4v0	192	7	RCTs	rct	NNS
cord-017161-lcqrd4v0	192	8	to	to	TO
cord-017161-lcqrd4v0	192	9	establish	establish	VB
cord-017161-lcqrd4v0	192	10	the	the	DT
cord-017161-lcqrd4v0	192	11	optimal	optimal	JJ
cord-017161-lcqrd4v0	192	12	management	management	NN
cord-017161-lcqrd4v0	192	13	of	of	IN
cord-017161-lcqrd4v0	192	14	KD	KD	NNP
cord-017161-lcqrd4v0	192	15	,	,	,
cord-017161-lcqrd4v0	192	16	and	and	CC
cord-017161-lcqrd4v0	192	17	in	in	IN
cord-017161-lcqrd4v0	192	18	particular	particular	JJ
cord-017161-lcqrd4v0	192	19	IVIG	IVIG	NNP
cord-017161-lcqrd4v0	192	20	-	-	HYPH
cord-017161-lcqrd4v0	192	21	resistant	resistant	JJ
cord-017161-lcqrd4v0	192	22	KD	KD	NNP
cord-017161-lcqrd4v0	192	23	,	,	,
cord-017161-lcqrd4v0	192	24	are	be	VBP
cord-017161-lcqrd4v0	192	25	needed	need	VBN
cord-017161-lcqrd4v0	192	26	[	[	-LRB-
cord-017161-lcqrd4v0	192	27	102	102	CD
cord-017161-lcqrd4v0	192	28	]	]	-RRB-
cord-017161-lcqrd4v0	192	29	.	.	.
cord-017161-lcqrd4v0	193	1	In	in	IN
cord-017161-lcqrd4v0	193	2	that	that	DT
cord-017161-lcqrd4v0	193	3	respect	respect	NN
cord-017161-lcqrd4v0	193	4	a	a	DT
cord-017161-lcqrd4v0	193	5	multi	multi	JJ
cord-017161-lcqrd4v0	193	6	-	-	JJ
cord-017161-lcqrd4v0	193	7	centre	centre	JJ
cord-017161-lcqrd4v0	193	8	,	,	,
cord-017161-lcqrd4v0	193	9	double	double	JJ
cord-017161-lcqrd4v0	193	10	-	-	HYPH
cord-017161-lcqrd4v0	193	11	blind	blind	JJ
cord-017161-lcqrd4v0	193	12	,	,	,
cord-017161-lcqrd4v0	193	13	randomized	randomized	JJ
cord-017161-lcqrd4v0	193	14	,	,	,
cord-017161-lcqrd4v0	193	15	placebo	placebo	NN
cord-017161-lcqrd4v0	193	16	-	-	HYPH
cord-017161-lcqrd4v0	193	17	controlled	control	VBN
cord-017161-lcqrd4v0	193	18	trial	trial	NN
cord-017161-lcqrd4v0	193	19	intended	intend	VBN
cord-017161-lcqrd4v0	193	20	to	to	TO
cord-017161-lcqrd4v0	193	21	assess	assess	VB
cord-017161-lcqrd4v0	193	22	the	the	DT
cord-017161-lcqrd4v0	193	23	ef	ef	NNP
cord-017161-lcqrd4v0	193	24	fi	fi	NN
cord-017161-lcqrd4v0	193	25	cacy	cacy	NN
cord-017161-lcqrd4v0	193	26	of	of	IN
cord-017161-lcqrd4v0	193	27	etanercept	etanercept	NNP
cord-017161-lcqrd4v0	193	28	(	(	-LRB-
cord-017161-lcqrd4v0	193	29	a	a	DT
cord-017161-lcqrd4v0	193	30	fusion	fusion	NN
cord-017161-lcqrd4v0	193	31	protein	protein	NN
cord-017161-lcqrd4v0	193	32	combining	combine	VBG
cord-017161-lcqrd4v0	193	33	the	the	DT
cord-017161-lcqrd4v0	193	34	TNF	TNF	NNP
cord-017161-lcqrd4v0	193	35	receptor	receptor	NN
cord-017161-lcqrd4v0	193	36	2	2	CD
cord-017161-lcqrd4v0	193	37	and	and	CC
cord-017161-lcqrd4v0	193	38	the	the	DT
cord-017161-lcqrd4v0	193	39	Fc	Fc	NNP
cord-017161-lcqrd4v0	193	40	component	component	NN
cord-017161-lcqrd4v0	193	41	of	of	IN
cord-017161-lcqrd4v0	193	42	human	human	JJ
cord-017161-lcqrd4v0	193	43	IgG1	IgG1	NNP
cord-017161-lcqrd4v0	193	44	)	)	-RRB-
cord-017161-lcqrd4v0	193	45	in	in	IN
cord-017161-lcqrd4v0	193	46	reducing	reduce	VBG
cord-017161-lcqrd4v0	193	47	the	the	DT
cord-017161-lcqrd4v0	193	48	IVIG	IVIG	NNP
cord-017161-lcqrd4v0	193	49	refractory	refractory	JJ
cord-017161-lcqrd4v0	193	50	rate	rate	NN
cord-017161-lcqrd4v0	193	51	during	during	IN
cord-017161-lcqrd4v0	193	52	treatment	treatment	NN
cord-017161-lcqrd4v0	193	53	of	of	IN
cord-017161-lcqrd4v0	193	54	acute	acute	JJ
cord-017161-lcqrd4v0	193	55	KD	KD	NNP
cord-017161-lcqrd4v0	193	56	is	be	VBZ
cord-017161-lcqrd4v0	193	57	ongoing	ongoing	JJ
cord-017161-lcqrd4v0	193	58	[	[	-LRB-
cord-017161-lcqrd4v0	193	59	103	103	CD
cord-017161-lcqrd4v0	193	60	]	]	-RRB-
cord-017161-lcqrd4v0	193	61	.	.	.
cord-017161-lcqrd4v0	194	1	In	in	IN
cord-017161-lcqrd4v0	194	2	the	the	DT
cord-017161-lcqrd4v0	194	3	convalescent	convalescent	JJ
cord-017161-lcqrd4v0	194	4	phase	phase	NN
cord-017161-lcqrd4v0	194	5	of	of	IN
cord-017161-lcqrd4v0	194	6	the	the	DT
cord-017161-lcqrd4v0	194	7	condition	condition	NN
cord-017161-lcqrd4v0	194	8	,	,	,
cord-017161-lcqrd4v0	194	9	if	if	IN
cord-017161-lcqrd4v0	194	10	aneurysms	aneurysm	NNS
cord-017161-lcqrd4v0	194	11	persist	persist	VBP
cord-017161-lcqrd4v0	194	12	,	,	,
cord-017161-lcqrd4v0	194	13	anti	anti	JJ
cord-017161-lcqrd4v0	194	14	-	-	JJ
cord-017161-lcqrd4v0	194	15	platelet	platelet	JJ
cord-017161-lcqrd4v0	194	16	therapy	therapy	NN
cord-017161-lcqrd4v0	194	17	in	in	IN
cord-017161-lcqrd4v0	194	18	the	the	DT
cord-017161-lcqrd4v0	194	19	form	form	NN
cord-017161-lcqrd4v0	194	20	of	of	IN
cord-017161-lcqrd4v0	194	21	low	low	JJ
cord-017161-lcqrd4v0	194	22	-	-	HYPH
cord-017161-lcqrd4v0	194	23	dose	dose	NN
cord-017161-lcqrd4v0	194	24	aspirin	aspirin	NN
cord-017161-lcqrd4v0	194	25	should	should	MD
cord-017161-lcqrd4v0	194	26	be	be	VB
cord-017161-lcqrd4v0	194	27	continued	continue	VBN
cord-017161-lcqrd4v0	194	28	long	long	JJ
cord-017161-lcqrd4v0	194	29	term	term	NN
cord-017161-lcqrd4v0	194	30	until	until	IN
cord-017161-lcqrd4v0	194	31	the	the	DT
cord-017161-lcqrd4v0	194	32	aneurysms	aneurysm	NNS
cord-017161-lcqrd4v0	194	33	resolve	resolve	VBP
cord-017161-lcqrd4v0	194	34	[	[	-LRB-
cord-017161-lcqrd4v0	194	35	56	56	CD
cord-017161-lcqrd4v0	194	36	]	]	-RRB-
cord-017161-lcqrd4v0	194	37	.	.	.
cord-017161-lcqrd4v0	195	1	In	in	IN
cord-017161-lcqrd4v0	195	2	the	the	DT
cord-017161-lcqrd4v0	195	3	presence	presence	NN
cord-017161-lcqrd4v0	195	4	of	of	IN
cord-017161-lcqrd4v0	195	5	giant	giant	JJ
cord-017161-lcqrd4v0	195	6	aneurysms	aneurysm	NNS
cord-017161-lcqrd4v0	195	7	(	(	-LRB-
cord-017161-lcqrd4v0	195	8	greater	great	JJR
cord-017161-lcqrd4v0	195	9	than	than	IN
cord-017161-lcqrd4v0	195	10	8	8	CD
cord-017161-lcqrd4v0	195	11	mm	mm	CD
cord-017161-lcqrd4v0	195	12	)	)	-RRB-
cord-017161-lcqrd4v0	195	13	,	,	,
cord-017161-lcqrd4v0	195	14	warfarin	warfarin	NNP
cord-017161-lcqrd4v0	195	15	is	be	VBZ
cord-017161-lcqrd4v0	195	16	recommended	recommend	VBN
cord-017161-lcqrd4v0	195	17	in	in	IN
cord-017161-lcqrd4v0	195	18	addition	addition	NN
cord-017161-lcqrd4v0	195	19	to	to	IN
cord-017161-lcqrd4v0	195	20	aspirin	aspirin	VB
cord-017161-lcqrd4v0	195	21	[	[	-LRB-
cord-017161-lcqrd4v0	195	22	104	104	CD
cord-017161-lcqrd4v0	195	23	]	]	-RRB-
cord-017161-lcqrd4v0	195	24	.	.	.
cord-017161-lcqrd4v0	196	1	Some	some	DT
cord-017161-lcqrd4v0	196	2	patients	patient	NNS
cord-017161-lcqrd4v0	196	3	may	may	MD
cord-017161-lcqrd4v0	196	4	require	require	VB
cord-017161-lcqrd4v0	196	5	coronary	coronary	JJ
cord-017161-lcqrd4v0	196	6	angioplasty	angioplasty	NN
cord-017161-lcqrd4v0	196	7	or	or	CC
cord-017161-lcqrd4v0	196	8	a	a	DT
cord-017161-lcqrd4v0	196	9	revascularization	revascularization	NN
cord-017161-lcqrd4v0	196	10	procedure	procedure	NN
cord-017161-lcqrd4v0	196	11	should	should	MD
cord-017161-lcqrd4v0	196	12	ischemic	ischemic	JJ
cord-017161-lcqrd4v0	196	13	symptoms	symptom	NNS
cord-017161-lcqrd4v0	196	14	arise	arise	VB
cord-017161-lcqrd4v0	196	15	or	or	CC
cord-017161-lcqrd4v0	196	16	evidence	evidence	NN
cord-017161-lcqrd4v0	196	17	of	of	IN
cord-017161-lcqrd4v0	196	18	obstruction	obstruction	NN
cord-017161-lcqrd4v0	196	19	occur	occur	VBP
cord-017161-lcqrd4v0	196	20	[	[	-LRB-
cord-017161-lcqrd4v0	196	21	105	105	CD
cord-017161-lcqrd4v0	196	22	]	]	-RRB-
cord-017161-lcqrd4v0	196	23	.	.	.
cord-017161-lcqrd4v0	197	1	The	the	DT
cord-017161-lcqrd4v0	197	2	acute	acute	JJ
cord-017161-lcqrd4v0	197	3	mortality	mortality	NN
cord-017161-lcqrd4v0	197	4	of	of	IN
cord-017161-lcqrd4v0	197	5	KD	KD	NNP
cord-017161-lcqrd4v0	197	6	in	in	IN
cord-017161-lcqrd4v0	197	7	Japan	Japan	NNP
cord-017161-lcqrd4v0	197	8	is	be	VBZ
cord-017161-lcqrd4v0	197	9	1.14	1.14	CD
cord-017161-lcqrd4v0	197	10	[	[	-LRB-
cord-017161-lcqrd4v0	197	11	105	105	CD
cord-017161-lcqrd4v0	197	12	]	]	-RRB-
cord-017161-lcqrd4v0	197	13	.	.	.
cord-017161-lcqrd4v0	198	1	About	about	RB
cord-017161-lcqrd4v0	198	2	20	20	CD
cord-017161-lcqrd4v0	198	3	%	%	NN
cord-017161-lcqrd4v0	198	4	of	of	IN
cord-017161-lcqrd4v0	198	5	patients	patient	NNS
cord-017161-lcqrd4v0	198	6	who	who	WP
cord-017161-lcqrd4v0	198	7	develop	develop	VBP
cord-017161-lcqrd4v0	198	8	CAAs	caa	NNS
cord-017161-lcqrd4v0	198	9	during	during	IN
cord-017161-lcqrd4v0	198	10	the	the	DT
cord-017161-lcqrd4v0	198	11	acute	acute	JJ
cord-017161-lcqrd4v0	198	12	disease	disease	NN
cord-017161-lcqrd4v0	198	13	will	will	MD
cord-017161-lcqrd4v0	198	14	develop	develop	VB
cord-017161-lcqrd4v0	198	15	coronary	coronary	JJ
cord-017161-lcqrd4v0	198	16	artery	artery	NN
cord-017161-lcqrd4v0	198	17	stenoses	stenosis	NNS
cord-017161-lcqrd4v0	198	18	,	,	,
cord-017161-lcqrd4v0	198	19	and	and	CC
cord-017161-lcqrd4v0	198	20	the	the	DT
cord-017161-lcqrd4v0	198	21	risk	risk	NN
cord-017161-lcqrd4v0	198	22	is	be	VBZ
cord-017161-lcqrd4v0	198	23	greater	great	JJR
cord-017161-lcqrd4v0	198	24	with	with	IN
cord-017161-lcqrd4v0	198	25	large	large	JJ
cord-017161-lcqrd4v0	198	26	(	(	-LRB-
cord-017161-lcqrd4v0	198	27	giant	giant	NN
cord-017161-lcqrd4v0	198	28	)	)	-RRB-
cord-017161-lcqrd4v0	198	29	aneurysms	aneurysm	NNS
cord-017161-lcqrd4v0	198	30	[	[	-LRB-
cord-017161-lcqrd4v0	198	31	105	105	CD
cord-017161-lcqrd4v0	198	32	]	]	-RRB-
cord-017161-lcqrd4v0	198	33	.	.	.
cord-017161-lcqrd4v0	199	1	However	however	RB
cord-017161-lcqrd4v0	199	2	,	,	,
cord-017161-lcqrd4v0	199	3	emerging	emerge	VBG
cord-017161-lcqrd4v0	199	4	data	datum	NNS
cord-017161-lcqrd4v0	199	5	suggest	suggest	VBP
cord-017161-lcqrd4v0	199	6	that	that	IN
cord-017161-lcqrd4v0	199	7	,	,	,
cord-017161-lcqrd4v0	199	8	in	in	IN
cord-017161-lcqrd4v0	199	9	spite	spite	NN
cord-017161-lcqrd4v0	199	10	of	of	IN
cord-017161-lcqrd4v0	199	11	seeming	seeming	JJ
cord-017161-lcqrd4v0	199	12	recovery	recovery	NN
cord-017161-lcqrd4v0	199	13	,	,	,
cord-017161-lcqrd4v0	199	14	there	there	EX
cord-017161-lcqrd4v0	199	15	are	be	VBP
cord-017161-lcqrd4v0	199	16	long	long	JJ
cord-017161-lcqrd4v0	199	17	-	-	HYPH
cord-017161-lcqrd4v0	199	18	term	term	NN
cord-017161-lcqrd4v0	199	19	cardiovascular	cardiovascular	JJ
cord-017161-lcqrd4v0	199	20	sequelae	sequela	NNS
cord-017161-lcqrd4v0	199	21	for	for	IN
cord-017161-lcqrd4v0	199	22	patients	patient	NNS
cord-017161-lcqrd4v0	199	23	with	with	IN
cord-017161-lcqrd4v0	199	24	KD	KD	NNP
cord-017161-lcqrd4v0	199	25	that	that	WDT
cord-017161-lcqrd4v0	199	26	persist	persist	VBP
cord-017161-lcqrd4v0	199	27	into	into	IN
cord-017161-lcqrd4v0	199	28	adult	adult	NN
cord-017161-lcqrd4v0	199	29	life	life	NN
cord-017161-lcqrd4v0	199	30	and	and	CC
cord-017161-lcqrd4v0	199	31	that	that	DT
cord-017161-lcqrd4v0	199	32	may	may	MD
cord-017161-lcqrd4v0	199	33	have	have	VB
cord-017161-lcqrd4v0	199	34	important	important	JJ
cord-017161-lcqrd4v0	199	35	implications	implication	NNS
cord-017161-lcqrd4v0	199	36	[	[	-LRB-
cord-017161-lcqrd4v0	199	37	106	106	CD
cord-017161-lcqrd4v0	199	38	]	]	-RRB-
cord-017161-lcqrd4v0	199	39	.	.	.
cord-017161-lcqrd4v0	200	1	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	200	2	-	-	HYPH
cord-017161-lcqrd4v0	200	3	associated	associate	VBN
cord-017161-lcqrd4v0	200	4	vasculitides	vasculitide	NNS
cord-017161-lcqrd4v0	200	5	(	(	-LRB-
cord-017161-lcqrd4v0	200	6	AAV	AAV	NNP
cord-017161-lcqrd4v0	200	7	)	)	-RRB-
cord-017161-lcqrd4v0	200	8	are	be	VBP
cord-017161-lcqrd4v0	200	9	small	small	JJ
cord-017161-lcqrd4v0	200	10	-	-	HYPH
cord-017161-lcqrd4v0	200	11	vessel	vessel	NN
cord-017161-lcqrd4v0	200	12	vasculitides	vasculitide	NNS
cord-017161-lcqrd4v0	200	13	characterized	characterize	VBN
cord-017161-lcqrd4v0	200	14	by	by	IN
cord-017161-lcqrd4v0	200	15	necrotizing	necrotize	VBG
cord-017161-lcqrd4v0	200	16	in	in	IN
cord-017161-lcqrd4v0	200	17	fl	fl	NNP
cord-017161-lcqrd4v0	200	18	ammation	ammation	NN
cord-017161-lcqrd4v0	200	19	of	of	IN
cord-017161-lcqrd4v0	200	20	small	small	JJ
cord-017161-lcqrd4v0	200	21	vessels	vessel	NNS
cord-017161-lcqrd4v0	200	22	in	in	IN
cord-017161-lcqrd4v0	200	23	association	association	NN
cord-017161-lcqrd4v0	200	24	with	with	IN
cord-017161-lcqrd4v0	200	25	autoantibodies	autoantibody	NNS
cord-017161-lcqrd4v0	200	26	to	to	IN
cord-017161-lcqrd4v0	200	27	neutrophil	neutrophil	VB
cord-017161-lcqrd4v0	200	28	constituents	constituent	NNS
cord-017161-lcqrd4v0	200	29	-	-	:
cord-017161-lcqrd4v0	200	30	in	in	IN
cord-017161-lcqrd4v0	200	31	particular	particular	JJ
cord-017161-lcqrd4v0	200	32	,	,	,
cord-017161-lcqrd4v0	200	33	proteinase	proteinase	NN
cord-017161-lcqrd4v0	200	34	3	3	CD
cord-017161-lcqrd4v0	200	35	(	(	-LRB-
cord-017161-lcqrd4v0	200	36	PR3	PR3	NNP
cord-017161-lcqrd4v0	200	37	)	)	-RRB-
cord-017161-lcqrd4v0	200	38	and	and	CC
cord-017161-lcqrd4v0	200	39	myeloperoxidase	myeloperoxidase	NNP
cord-017161-lcqrd4v0	200	40	(	(	-LRB-
cord-017161-lcqrd4v0	200	41	MPO	MPO	NNP
cord-017161-lcqrd4v0	200	42	)	)	-RRB-
cord-017161-lcqrd4v0	200	43	[	[	-LRB-
cord-017161-lcqrd4v0	200	44	107	107	CD
cord-017161-lcqrd4v0	200	45	,	,	,
cord-017161-lcqrd4v0	200	46	108	108	CD
cord-017161-lcqrd4v0	200	47	]	]	-RRB-
cord-017161-lcqrd4v0	200	48	.	.	.
cord-017161-lcqrd4v0	201	1	The	the	DT
cord-017161-lcqrd4v0	201	2	AAV	AAV	NNP
cord-017161-lcqrd4v0	201	3	comprise	comprise	VBP
cord-017161-lcqrd4v0	201	4	Wegener	Wegener	NNP
cord-017161-lcqrd4v0	201	5	's	's	POS
cord-017161-lcqrd4v0	201	6	granulomatosis	granulomatosis	NN
cord-017161-lcqrd4v0	201	7	(	(	-LRB-
cord-017161-lcqrd4v0	201	8	WG	WG	NNP
cord-017161-lcqrd4v0	201	9	,	,	,
cord-017161-lcqrd4v0	201	10	now	now	RB
cord-017161-lcqrd4v0	201	11	also	also	RB
cord-017161-lcqrd4v0	201	12	referred	refer	VBD
cord-017161-lcqrd4v0	201	13	to	to	IN
cord-017161-lcqrd4v0	201	14	as	as	RB
cord-017161-lcqrd4v0	201	15	granulomatous	granulomatous	JJ
cord-017161-lcqrd4v0	201	16	polyangiitis	polyangiitis	NN
cord-017161-lcqrd4v0	201	17	,	,	,
cord-017161-lcqrd4v0	201	18	although	although	IN
cord-017161-lcqrd4v0	201	19	for	for	IN
cord-017161-lcqrd4v0	201	20	the	the	DT
cord-017161-lcqrd4v0	201	21	purposes	purpose	NNS
cord-017161-lcqrd4v0	201	22	of	of	IN
cord-017161-lcqrd4v0	201	23	this	this	DT
cord-017161-lcqrd4v0	201	24	review	review	NN
cord-017161-lcqrd4v0	201	25	the	the	DT
cord-017161-lcqrd4v0	201	26	term	term	NN
cord-017161-lcqrd4v0	201	27	WG	WG	NNP
cord-017161-lcqrd4v0	201	28	is	be	VBZ
cord-017161-lcqrd4v0	201	29	used	use	VBN
cord-017161-lcqrd4v0	201	30	)	)	-RRB-
cord-017161-lcqrd4v0	201	31	,	,	,
cord-017161-lcqrd4v0	201	32	microscopic	microscopic	JJ
cord-017161-lcqrd4v0	201	33	polyangiitis	polyangiitis	NN
cord-017161-lcqrd4v0	201	34	(	(	-LRB-
cord-017161-lcqrd4v0	201	35	MPA	MPA	NNP
cord-017161-lcqrd4v0	201	36	)	)	-RRB-
cord-017161-lcqrd4v0	201	37	,	,	,
cord-017161-lcqrd4v0	201	38	including	include	VBG
cord-017161-lcqrd4v0	201	39	its	-PRON-	PRP$
cord-017161-lcqrd4v0	201	40	renal	renal	JJ
cord-017161-lcqrd4v0	201	41	-	-	HYPH
cord-017161-lcqrd4v0	201	42	limited	limited	JJ
cord-017161-lcqrd4v0	201	43	(	(	-LRB-
cord-017161-lcqrd4v0	201	44	RL	RL	NNP
cord-017161-lcqrd4v0	201	45	)	)	-RRB-
cord-017161-lcqrd4v0	201	46	subset	subset	VBN
cord-017161-lcqrd4v0	201	47	designated	designate	VBN
cord-017161-lcqrd4v0	201	48	as	as	IN
cord-017161-lcqrd4v0	201	49	idiopathic	idiopathic	JJ
cord-017161-lcqrd4v0	201	50	necrotizing	necrotize	VBG
cord-017161-lcqrd4v0	201	51	crescentic	crescentic	JJ
cord-017161-lcqrd4v0	201	52	glomerulonephritis	glomerulonephritis	NN
cord-017161-lcqrd4v0	201	53	(	(	-LRB-
cord-017161-lcqrd4v0	201	54	iNCGN	iNCGN	NNP
cord-017161-lcqrd4v0	201	55	)	)	-RRB-
cord-017161-lcqrd4v0	201	56	,	,	,
cord-017161-lcqrd4v0	201	57	and	and	CC
cord-017161-lcqrd4v0	201	58	Churg	Churg	NNP
cord-017161-lcqrd4v0	201	59	-	-	HYPH
cord-017161-lcqrd4v0	201	60	Strauss	Strauss	NNP
cord-017161-lcqrd4v0	201	61	syndrome	syndrome	NN
cord-017161-lcqrd4v0	201	62	(	(	-LRB-
cord-017161-lcqrd4v0	201	63	CSS	css	NN
cord-017161-lcqrd4v0	201	64	)	)	-RRB-
cord-017161-lcqrd4v0	201	65	[	[	-LRB-
cord-017161-lcqrd4v0	201	66	107	107	CD
cord-017161-lcqrd4v0	201	67	,	,	,
cord-017161-lcqrd4v0	201	68	108	108	CD
cord-017161-lcqrd4v0	201	69	]	]	-RRB-
cord-017161-lcqrd4v0	201	70	.	.	.
cord-017161-lcqrd4v0	202	1	Although	although	IN
cord-017161-lcqrd4v0	202	2	rare	rare	JJ
cord-017161-lcqrd4v0	202	3	,	,	,
cord-017161-lcqrd4v0	202	4	AAV	AAV	NNP
cord-017161-lcqrd4v0	202	5	do	do	VBP
cord-017161-lcqrd4v0	202	6	occur	occur	VB
cord-017161-lcqrd4v0	202	7	in	in	IN
cord-017161-lcqrd4v0	202	8	childhood	childhood	NN
cord-017161-lcqrd4v0	202	9	and	and	CC
cord-017161-lcqrd4v0	202	10	are	be	VBP
cord-017161-lcqrd4v0	202	11	associated	associate	VBN
cord-017161-lcqrd4v0	202	12	with	with	IN
cord-017161-lcqrd4v0	202	13	signi	signi	NNP
cord-017161-lcqrd4v0	202	14	fi	fi	NNP
cord-017161-lcqrd4v0	202	15	ca	can	MD
cord-017161-lcqrd4v0	202	16	nt	not	RB
cord-017161-lcqrd4v0	202	17	morbidity	morbidity	NN
cord-017161-lcqrd4v0	202	18	and	and	CC
cord-017161-lcqrd4v0	202	19	mortality	mortality	NN
cord-017161-lcqrd4v0	202	20	[	[	-LRB-
cord-017161-lcqrd4v0	202	21	109	109	CD
cord-017161-lcqrd4v0	202	22	]	]	-RRB-
cord-017161-lcqrd4v0	202	23	.	.	.
cord-017161-lcqrd4v0	203	1	The	the	DT
cord-017161-lcqrd4v0	203	2	pathogenesis	pathogenesis	NN
cord-017161-lcqrd4v0	203	3	of	of	IN
cord-017161-lcqrd4v0	203	4	AAV	AAV	NNP
cord-017161-lcqrd4v0	203	5	is	be	VBZ
cord-017161-lcqrd4v0	203	6	still	still	RB
cord-017161-lcqrd4v0	203	7	not	not	RB
cord-017161-lcqrd4v0	203	8	fully	fully	RB
cord-017161-lcqrd4v0	203	9	elucidated	elucidate	VBN
cord-017161-lcqrd4v0	203	10	,	,	,
cord-017161-lcqrd4v0	203	11	but	but	CC
cord-017161-lcqrd4v0	203	12	clinical	clinical	JJ
cord-017161-lcqrd4v0	203	13	as	as	RB
cord-017161-lcqrd4v0	203	14	well	well	RB
cord-017161-lcqrd4v0	203	15	as	as	IN
cord-017161-lcqrd4v0	203	16	experimental	experimental	JJ
cord-017161-lcqrd4v0	203	17	data	datum	NNS
cord-017161-lcqrd4v0	203	18	strongly	strongly	RB
cord-017161-lcqrd4v0	203	19	suggest	suggest	VBP
cord-017161-lcqrd4v0	203	20	a	a	DT
cord-017161-lcqrd4v0	203	21	role	role	NN
cord-017161-lcqrd4v0	203	22	for	for	IN
cord-017161-lcqrd4v0	203	23	autoimmune	autoimmune	JJ
cord-017161-lcqrd4v0	203	24	responses	response	NNS
cord-017161-lcqrd4v0	203	25	to	to	IN
cord-017161-lcqrd4v0	203	26	PR3	PR3	NNP
cord-017161-lcqrd4v0	203	27	and	and	CC
cord-017161-lcqrd4v0	203	28	MPO	MPO	NNP
cord-017161-lcqrd4v0	203	29	in	in	IN
cord-017161-lcqrd4v0	203	30	disease	disease	NN
cord-017161-lcqrd4v0	203	31	development	development	NN
cord-017161-lcqrd4v0	203	32	[	[	-LRB-
cord-017161-lcqrd4v0	203	33	110	110	CD
cord-017161-lcqrd4v0	203	34	]	]	-RRB-
cord-017161-lcqrd4v0	203	35	.	.	.
cord-017161-lcqrd4v0	204	1	The	the	DT
cord-017161-lcqrd4v0	204	2	most	most	RBS
cord-017161-lcqrd4v0	204	3	accepted	accepted	JJ
cord-017161-lcqrd4v0	204	4	model	model	NN
cord-017161-lcqrd4v0	204	5	of	of	IN
cord-017161-lcqrd4v0	204	6	pathogenesis	pathogenesis	NN
cord-017161-lcqrd4v0	204	7	suggests	suggest	VBZ
cord-017161-lcqrd4v0	204	8	that	that	IN
cord-017161-lcqrd4v0	204	9	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	204	10	activate	activate	VB
cord-017161-lcqrd4v0	204	11	cytokineprimed	cytokineprimed	JJ
cord-017161-lcqrd4v0	204	12	neutrophils	neutrophil	NNS
cord-017161-lcqrd4v0	204	13	within	within	IN
cord-017161-lcqrd4v0	204	14	the	the	DT
cord-017161-lcqrd4v0	204	15	microvasculature	microvasculature	NN
cord-017161-lcqrd4v0	204	16	,	,	,
cord-017161-lcqrd4v0	204	17	leading	lead	VBG
cord-017161-lcqrd4v0	204	18	to	to	IN
cord-017161-lcqrd4v0	204	19	bystander	bystander	NN
cord-017161-lcqrd4v0	204	20	damage	damage	NN
cord-017161-lcqrd4v0	204	21	to	to	IN
cord-017161-lcqrd4v0	204	22	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	204	23	cells	cell	NNS
cord-017161-lcqrd4v0	204	24	themselves	-PRON-	PRP
cord-017161-lcqrd4v0	204	25	and	and	CC
cord-017161-lcqrd4v0	204	26	rapid	rapid	JJ
cord-017161-lcqrd4v0	204	27	escalation	escalation	NN
cord-017161-lcqrd4v0	204	28	of	of	IN
cord-017161-lcqrd4v0	204	29	in	in	IN
cord-017161-lcqrd4v0	204	30	fl	fl	NNP
cord-017161-lcqrd4v0	204	31	ammation	ammation	NNP
cord-017161-lcqrd4v0	204	32	with	with	IN
cord-017161-lcqrd4v0	204	33	recruitment	recruitment	NN
cord-017161-lcqrd4v0	204	34	of	of	IN
cord-017161-lcqrd4v0	204	35	mononuclear	mononuclear	JJ
cord-017161-lcqrd4v0	204	36	cells	cell	NNS
cord-017161-lcqrd4v0	204	37	[	[	-LRB-
cord-017161-lcqrd4v0	204	38	111	111	CD
cord-017161-lcqrd4v0	204	39	]	]	-RRB-
cord-017161-lcqrd4v0	204	40	.	.	.
cord-017161-lcqrd4v0	205	1	Falk	Falk	NNP
cord-017161-lcqrd4v0	205	2	et	et	NNP
cord-017161-lcqrd4v0	205	3	al	al	NNP
cord-017161-lcqrd4v0	205	4	.	.	NNP
cord-017161-lcqrd4v0	205	5	demonstrated	demonstrate	VBN
cord-017161-lcqrd4v0	205	6	in	in	IN
cord-017161-lcqrd4v0	205	7	1990	1990	CD
cord-017161-lcqrd4v0	205	8	that	that	IN
cord-017161-lcqrd4v0	205	9	ANCAs	anca	NNS
cord-017161-lcqrd4v0	205	10	in	in	IN
cord-017161-lcqrd4v0	205	11	vitro	vitro	FW
cord-017161-lcqrd4v0	205	12	activate	activate	VBP
cord-017161-lcqrd4v0	205	13	neutrophils	neutrophil	NNS
cord-017161-lcqrd4v0	205	14	to	to	TO
cord-017161-lcqrd4v0	205	15	produce	produce	VB
cord-017161-lcqrd4v0	205	16	reactive	reactive	JJ
cord-017161-lcqrd4v0	205	17	oxygen	oxygen	NN
cord-017161-lcqrd4v0	205	18	species	specie	NNS
cord-017161-lcqrd4v0	205	19	and	and	CC
cord-017161-lcqrd4v0	205	20	release	release	NN
cord-017161-lcqrd4v0	205	21	of	of	IN
cord-017161-lcqrd4v0	205	22	lytic	lytic	JJ
cord-017161-lcqrd4v0	205	23	enzymes	enzyme	NNS
cord-017161-lcqrd4v0	205	24	[	[	-LRB-
cord-017161-lcqrd4v0	205	25	112	112	CD
cord-017161-lcqrd4v0	205	26	]	]	-RRB-
cord-017161-lcqrd4v0	205	27	.	.	.
cord-017161-lcqrd4v0	206	1	This	this	DT
cord-017161-lcqrd4v0	206	2	process	process	NN
cord-017161-lcqrd4v0	206	3	requires	require	VBZ
cord-017161-lcqrd4v0	206	4	priming	priming	NN
cord-017161-lcqrd4v0	206	5	of	of	IN
cord-017161-lcqrd4v0	206	6	neutrophils	neutrophil	NNS
cord-017161-lcqrd4v0	206	7	.	.	.
cord-017161-lcqrd4v0	207	1	Priming	priming	NN
cord-017161-lcqrd4v0	207	2	involves	involve	VBZ
cord-017161-lcqrd4v0	207	3	the	the	DT
cord-017161-lcqrd4v0	207	4	stimulation	stimulation	NN
cord-017161-lcqrd4v0	207	5	of	of	IN
cord-017161-lcqrd4v0	207	6	neutrophils	neutrophil	NNS
cord-017161-lcqrd4v0	207	7	with	with	IN
cord-017161-lcqrd4v0	207	8	low	low	JJ
cord-017161-lcqrd4v0	207	9	doses	dose	NNS
cord-017161-lcqrd4v0	207	10	of	of	IN
cord-017161-lcqrd4v0	207	11	proin	proin	NNP
cord-017161-lcqrd4v0	207	12	fl	fl	NNP
cord-017161-lcqrd4v0	207	13	ammatory	ammatory	NNP
cord-017161-lcqrd4v0	207	14	cytokines	cytokine	NNS
cord-017161-lcqrd4v0	207	15	that	that	WDT
cord-017161-lcqrd4v0	207	16	result	result	VBP
cord-017161-lcqrd4v0	207	17	,	,	,
cord-017161-lcqrd4v0	207	18	among	among	IN
cord-017161-lcqrd4v0	207	19	other	other	JJ
cord-017161-lcqrd4v0	207	20	things	thing	NNS
cord-017161-lcqrd4v0	207	21	,	,	,
cord-017161-lcqrd4v0	207	22	in	in	IN
cord-017161-lcqrd4v0	207	23	surface	surface	NN
cord-017161-lcqrd4v0	207	24	expression	expression	NN
cord-017161-lcqrd4v0	207	25	of	of	IN
cord-017161-lcqrd4v0	207	26	PR3	PR3	NNP
cord-017161-lcqrd4v0	207	27	/	/	SYM
cord-017161-lcqrd4v0	207	28	MPO	MPO	NNP
cord-017161-lcqrd4v0	207	29	on	on	IN
cord-017161-lcqrd4v0	207	30	the	the	DT
cord-017161-lcqrd4v0	207	31	neutrophil	neutrophil	NN
cord-017161-lcqrd4v0	207	32	membrane	membrane	NN
cord-017161-lcqrd4v0	207	33	but	but	CC
cord-017161-lcqrd4v0	207	34	without	without	IN
cord-017161-lcqrd4v0	207	35	full	full	JJ
cord-017161-lcqrd4v0	207	36	neutrophil	neutrophil	NN
cord-017161-lcqrd4v0	207	37	activation	activation	NN
cord-017161-lcqrd4v0	207	38	,	,	,
cord-017161-lcqrd4v0	207	39	before	before	IN
cord-017161-lcqrd4v0	207	40	their	-PRON-	PRP$
cord-017161-lcqrd4v0	207	41	interaction	interaction	NN
cord-017161-lcqrd4v0	207	42	with	with	IN
cord-017161-lcqrd4v0	207	43	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	207	44	[	[	-LRB-
cord-017161-lcqrd4v0	207	45	113	113	CD
cord-017161-lcqrd4v0	207	46	]	]	-RRB-
cord-017161-lcqrd4v0	207	47	.	.	.
cord-017161-lcqrd4v0	208	1	Primed	prime	VBN
cord-017161-lcqrd4v0	208	2	neutrophil	neutrophil	NN
cord-017161-lcqrd4v0	208	3	activation	activation	NN
cord-017161-lcqrd4v0	208	4	by	by	IN
cord-017161-lcqrd4v0	208	5	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	208	6	involves	involve	VBZ
cord-017161-lcqrd4v0	208	7	interaction	interaction	NN
cord-017161-lcqrd4v0	208	8	with	with	IN
cord-017161-lcqrd4v0	208	9	their	-PRON-	PRP$
cord-017161-lcqrd4v0	208	10	target	target	NN
cord-017161-lcqrd4v0	208	11	antigens	antigen	NNS
cord-017161-lcqrd4v0	208	12	on	on	IN
cord-017161-lcqrd4v0	208	13	the	the	DT
cord-017161-lcqrd4v0	208	14	neutrophil	neutrophil	NN
cord-017161-lcqrd4v0	208	15	membrane	membrane	NN
cord-017161-lcqrd4v0	208	16	and	and	CC
cord-017161-lcqrd4v0	208	17	also	also	RB
cord-017161-lcqrd4v0	208	18	with	with	IN
cord-017161-lcqrd4v0	208	19	Fc	Fc	NNP
cord-017161-lcqrd4v0	208	20	g	g	NNP
cord-017161-lcqrd4v0	208	21	receptors	receptor	NNS
cord-017161-lcqrd4v0	208	22	-	-	,
cord-017161-lcqrd4v0	208	23	in	in	IN
cord-017161-lcqrd4v0	208	24	particular	particular	JJ
cord-017161-lcqrd4v0	208	25	,	,	,
cord-017161-lcqrd4v0	208	26	Fc	Fc	NNP
cord-017161-lcqrd4v0	208	27	g	g	NNP
cord-017161-lcqrd4v0	208	28	RIIa	RIIa	NNS
cord-017161-lcqrd4v0	208	29	and	and	CC
cord-017161-lcqrd4v0	208	30	Fc	Fc	NNP
cord-017161-lcqrd4v0	208	31	g	g	NNP
cord-017161-lcqrd4v0	208	32	RIIIb	RIIIb	NNP
cord-017161-lcqrd4v0	208	33	[	[	-LRB-
cord-017161-lcqrd4v0	208	34	113	113	CD
cord-017161-lcqrd4v0	208	35	]	]	-RRB-
cord-017161-lcqrd4v0	208	36	.	.	.
cord-017161-lcqrd4v0	209	1	In	in	IN
cord-017161-lcqrd4v0	209	2	addition	addition	NN
cord-017161-lcqrd4v0	209	3	,	,	,
cord-017161-lcqrd4v0	209	4	Reumaux	Reumaux	NNP
cord-017161-lcqrd4v0	209	5	et	et	NNP
cord-017161-lcqrd4v0	209	6	al	al	NNP
cord-017161-lcqrd4v0	209	7	.	.	NNP
cord-017161-lcqrd4v0	209	8	showed	show	VBD
cord-017161-lcqrd4v0	209	9	that	that	IN
cord-017161-lcqrd4v0	209	10	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	209	11	-	-	HYPH
cord-017161-lcqrd4v0	209	12	induced	induce	VBN
cord-017161-lcqrd4v0	209	13	neutrophil	neutrophil	NN
cord-017161-lcqrd4v0	209	14	activation	activation	NN
cord-017161-lcqrd4v0	209	15	occurs	occur	VBZ
cord-017161-lcqrd4v0	209	16	only	only	RB
cord-017161-lcqrd4v0	209	17	when	when	WRB
cord-017161-lcqrd4v0	209	18	neutrophils	neutrophil	NNS
cord-017161-lcqrd4v0	209	19	are	be	VBP
cord-017161-lcqrd4v0	209	20	attached	attach	VBN
cord-017161-lcqrd4v0	209	21	to	to	IN
cord-017161-lcqrd4v0	209	22	a	a	DT
cord-017161-lcqrd4v0	209	23	surface	surface	NN
cord-017161-lcqrd4v0	209	24	and	and	CC
cord-017161-lcqrd4v0	209	25	not	not	RB
cord-017161-lcqrd4v0	209	26	when	when	WRB
cord-017161-lcqrd4v0	209	27	fl	fl	NNP
cord-017161-lcqrd4v0	209	28	oating	oate	VBG
cord-017161-lcqrd4v0	209	29	in	in	IN
cord-017161-lcqrd4v0	209	30	the	the	DT
cord-017161-lcqrd4v0	209	31	circulation	circulation	NN
cord-017161-lcqrd4v0	209	32	[	[	-LRB-
cord-017161-lcqrd4v0	209	33	114	114	CD
cord-017161-lcqrd4v0	209	34	]	]	-RRB-
cord-017161-lcqrd4v0	209	35	.	.	.
cord-017161-lcqrd4v0	210	1	Furthermore	furthermore	RB
cord-017161-lcqrd4v0	210	2	,	,	,
cord-017161-lcqrd4v0	210	3	Radford	Radford	NNP
cord-017161-lcqrd4v0	210	4	et	et	NNP
cord-017161-lcqrd4v0	210	5	al	al	NNP
cord-017161-lcqrd4v0	210	6	.	.	NNP
cord-017161-lcqrd4v0	210	7	demonstrated	demonstrate	VBD
cord-017161-lcqrd4v0	210	8	that	that	IN
cord-017161-lcqrd4v0	210	9	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	210	10	can	can	MD
cord-017161-lcqrd4v0	210	11	directly	directly	RB
cord-017161-lcqrd4v0	210	12	activate	activate	VB
cord-017161-lcqrd4v0	210	13	neutrophils	neutrophil	NNS
cord-017161-lcqrd4v0	210	14	to	to	TO
cord-017161-lcqrd4v0	210	15	become	become	VB
cord-017161-lcqrd4v0	210	16	fi	fi	NNP
cord-017161-lcqrd4v0	210	17	rmly	rmly	NN
cord-017161-lcqrd4v0	210	18	adherent	adherent	JJ
cord-017161-lcqrd4v0	210	19	to	to	IN
cord-017161-lcqrd4v0	210	20	vessel	vessel	NN
cord-017161-lcqrd4v0	210	21	walls	wall	NNS
cord-017161-lcqrd4v0	210	22	,	,	,
cord-017161-lcqrd4v0	210	23	where	where	WRB
cord-017161-lcqrd4v0	210	24	they	-PRON-	PRP
cord-017161-lcqrd4v0	210	25	may	may	MD
cord-017161-lcqrd4v0	210	26	obstruct	obstruct	VB
cord-017161-lcqrd4v0	210	27	fl	fl	NNP
cord-017161-lcqrd4v0	210	28	ow	ow	UH
cord-017161-lcqrd4v0	210	29	,	,	,
cord-017161-lcqrd4v0	210	30	initiate	initiate	VB
cord-017161-lcqrd4v0	210	31	tissue	tissue	NN
cord-017161-lcqrd4v0	210	32	damage	damage	NN
cord-017161-lcqrd4v0	210	33	and	and	CC
cord-017161-lcqrd4v0	210	34	contribute	contribute	VB
cord-017161-lcqrd4v0	210	35	to	to	IN
cord-017161-lcqrd4v0	210	36	the	the	DT
cord-017161-lcqrd4v0	210	37	pathogenesis	pathogenesis	NN
cord-017161-lcqrd4v0	210	38	of	of	IN
cord-017161-lcqrd4v0	210	39	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	210	40	[	[	-LRB-
cord-017161-lcqrd4v0	210	41	115	115	CD
cord-017161-lcqrd4v0	210	42	]	]	-RRB-
cord-017161-lcqrd4v0	210	43	.	.	.
cord-017161-lcqrd4v0	211	1	These	these	DT
cord-017161-lcqrd4v0	211	2	effects	effect	NNS
cord-017161-lcqrd4v0	211	3	can	can	MD
cord-017161-lcqrd4v0	211	4	be	be	VB
cord-017161-lcqrd4v0	211	5	blocked	block	VBN
cord-017161-lcqrd4v0	211	6	by	by	IN
cord-017161-lcqrd4v0	211	7	antibodies	antibody	NNS
cord-017161-lcqrd4v0	211	8	to	to	IN
cord-017161-lcqrd4v0	211	9	Fc	Fc	NNP
cord-017161-lcqrd4v0	211	10	g	g	NNP
cord-017161-lcqrd4v0	211	11	RIIa	RIIa	NNS
cord-017161-lcqrd4v0	211	12	and	and	CC
cord-017161-lcqrd4v0	211	13	by	by	IN
cord-017161-lcqrd4v0	211	14	antibodies	antibody	NNS
cord-017161-lcqrd4v0	211	15	to	to	IN
cord-017161-lcqrd4v0	211	16	CD11b	CD11b	NNPS
cord-017161-lcqrd4v0	211	17	[	[	-LRB-
cord-017161-lcqrd4v0	211	18	115	115	CD
cord-017161-lcqrd4v0	211	19	]	]	-RRB-
cord-017161-lcqrd4v0	211	20	.	.	.
cord-017161-lcqrd4v0	212	1	In	in	IN
cord-017161-lcqrd4v0	212	2	more	more	JJR
cord-017161-lcqrd4v0	212	3	detail	detail	NN
cord-017161-lcqrd4v0	212	4	,	,	,
cord-017161-lcqrd4v0	212	5	Savage	Savage	NNP
cord-017161-lcqrd4v0	212	6	et	et	NNP
cord-017161-lcqrd4v0	212	7	al	al	NNP
cord-017161-lcqrd4v0	212	8	.	.	NNP
cord-017161-lcqrd4v0	212	9	showed	show	VBD
cord-017161-lcqrd4v0	212	10	that	that	IN
cord-017161-lcqrd4v0	212	11	activation	activation	NN
cord-017161-lcqrd4v0	212	12	of	of	IN
cord-017161-lcqrd4v0	212	13	neutrophils	neutrophil	NNS
cord-017161-lcqrd4v0	212	14	by	by	IN
cord-017161-lcqrd4v0	212	15	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	212	16	causes	cause	VBZ
cord-017161-lcqrd4v0	212	17	integrin	integrin	NN
cord-017161-lcqrd4v0	212	18	-	-	HYPH
cord-017161-lcqrd4v0	212	19	and	and	CC
cord-017161-lcqrd4v0	212	20	cytokine	cytokine	JJ
cord-017161-lcqrd4v0	212	21	receptor	receptor	NN
cord-017161-lcqrd4v0	212	22	-	-	HYPH
cord-017161-lcqrd4v0	212	23	mediated	mediate	VBN
cord-017161-lcqrd4v0	212	24	adherence	adherence	NN
cord-017161-lcqrd4v0	212	25	to	to	IN
cord-017161-lcqrd4v0	212	26	cultured	cultured	JJ
cord-017161-lcqrd4v0	212	27	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	212	28	cells	cell	NNS
cord-017161-lcqrd4v0	212	29	and	and	CC
cord-017161-lcqrd4v0	212	30	transmigration	transmigration	NN
cord-017161-lcqrd4v0	212	31	across	across	IN
cord-017161-lcqrd4v0	212	32	the	the	DT
cord-017161-lcqrd4v0	212	33	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	212	34	layer	layer	NN
cord-017161-lcqrd4v0	212	35	[	[	-LRB-
cord-017161-lcqrd4v0	212	36	116	116	CD
cord-017161-lcqrd4v0	212	37	]	]	-RRB-
cord-017161-lcqrd4v0	212	38	.	.	.
cord-017161-lcqrd4v0	213	1	In	in	IN
cord-017161-lcqrd4v0	213	2	addition	addition	NN
cord-017161-lcqrd4v0	213	3	,	,	,
cord-017161-lcqrd4v0	213	4	activation	activation	NN
cord-017161-lcqrd4v0	213	5	of	of	IN
cord-017161-lcqrd4v0	213	6	neutrophils	neutrophil	NNS
cord-017161-lcqrd4v0	213	7	with	with	IN
cord-017161-lcqrd4v0	213	8	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	213	9	causes	cause	VBZ
cord-017161-lcqrd4v0	213	10	a	a	DT
cord-017161-lcqrd4v0	213	11	conformational	conformational	JJ
cord-017161-lcqrd4v0	213	12	change	change	NN
cord-017161-lcqrd4v0	213	13	in	in	IN
cord-017161-lcqrd4v0	213	14	beta-2	beta-2	NN
cord-017161-lcqrd4v0	213	15	integrins	integrin	NNS
cord-017161-lcqrd4v0	213	16	that	that	WDT
cord-017161-lcqrd4v0	213	17	enhances	enhance	VBZ
cord-017161-lcqrd4v0	213	18	ligand	ligand	NN
cord-017161-lcqrd4v0	213	19	binding	bind	VBG
cord-017161-lcqrd4v0	213	20	[	[	-LRB-
cord-017161-lcqrd4v0	213	21	116	116	CD
cord-017161-lcqrd4v0	213	22	]	]	-RRB-
cord-017161-lcqrd4v0	213	23	.	.	.
cord-017161-lcqrd4v0	214	1	A	a	DT
cord-017161-lcqrd4v0	214	2	role	role	NN
cord-017161-lcqrd4v0	214	3	for	for	IN
cord-017161-lcqrd4v0	214	4	adhesion	adhesion	NN
cord-017161-lcqrd4v0	214	5	molecules	molecule	NNS
cord-017161-lcqrd4v0	214	6	in	in	IN
cord-017161-lcqrd4v0	214	7	the	the	DT
cord-017161-lcqrd4v0	214	8	interaction	interaction	NN
cord-017161-lcqrd4v0	214	9	between	between	IN
cord-017161-lcqrd4v0	214	10	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	214	11	-	-	HYPH
cord-017161-lcqrd4v0	214	12	activated	activate	VBN
cord-017161-lcqrd4v0	214	13	neutrophils	neutrophil	NNS
cord-017161-lcqrd4v0	214	14	and	and	CC
cord-017161-lcqrd4v0	214	15	vessels	vessel	NNS
cord-017161-lcqrd4v0	214	16	also	also	RB
cord-017161-lcqrd4v0	214	17	is	be	VBZ
cord-017161-lcqrd4v0	214	18	supported	support	VBN
cord-017161-lcqrd4v0	214	19	by	by	IN
cord-017161-lcqrd4v0	214	20	immunohistologic	immunohistologic	JJ
cord-017161-lcqrd4v0	214	21	evidence	evidence	NN
cord-017161-lcqrd4v0	214	22	of	of	IN
cord-017161-lcqrd4v0	214	23	upregulated	upregulated	JJ
cord-017161-lcqrd4v0	214	24	adhesion	adhesion	NN
cord-017161-lcqrd4v0	214	25	molecules	molecule	NNS
cord-017161-lcqrd4v0	214	26	in	in	IN
cord-017161-lcqrd4v0	214	27	glomerular	glomerular	JJ
cord-017161-lcqrd4v0	214	28	lesions	lesion	NNS
cord-017161-lcqrd4v0	214	29	in	in	IN
cord-017161-lcqrd4v0	214	30	renal	renal	JJ
cord-017161-lcqrd4v0	214	31	biopsy	biopsy	NN
cord-017161-lcqrd4v0	214	32	specimens	specimen	NNS
cord-017161-lcqrd4v0	214	33	from	from	IN
cord-017161-lcqrd4v0	214	34	patients	patient	NNS
cord-017161-lcqrd4v0	214	35	with	with	IN
cord-017161-lcqrd4v0	214	36	AAV	AAV	NNP
cord-017161-lcqrd4v0	214	37	[	[	-LRB-
cord-017161-lcqrd4v0	214	38	117	117	CD
cord-017161-lcqrd4v0	214	39	]	]	-RRB-
cord-017161-lcqrd4v0	214	40	.	.	.
cord-017161-lcqrd4v0	215	1	In	in	IN
cord-017161-lcqrd4v0	215	2	addition	addition	NN
cord-017161-lcqrd4v0	215	3	to	to	IN
cord-017161-lcqrd4v0	215	4	binding	bind	VBG
cord-017161-lcqrd4v0	215	5	to	to	IN
cord-017161-lcqrd4v0	215	6	the	the	DT
cord-017161-lcqrd4v0	215	7	surface	surface	NN
cord-017161-lcqrd4v0	215	8	of	of	IN
cord-017161-lcqrd4v0	215	9	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	215	10	cells	cell	NNS
cord-017161-lcqrd4v0	215	11	,	,	,
cord-017161-lcqrd4v0	215	12	both	both	CC
cord-017161-lcqrd4v0	215	13	PR3	PR3	NNP
cord-017161-lcqrd4v0	215	14	and	and	CC
cord-017161-lcqrd4v0	215	15	MPO	MPO	NNP
cord-017161-lcqrd4v0	215	16	are	be	VBP
cord-017161-lcqrd4v0	215	17	internalized	internalize	VBN
cord-017161-lcqrd4v0	215	18	into	into	IN
cord-017161-lcqrd4v0	215	19	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	215	20	cells	cell	NNS
cord-017161-lcqrd4v0	215	21	,	,	,
cord-017161-lcqrd4v0	215	22	where	where	WRB
cord-017161-lcqrd4v0	215	23	they	-PRON-	PRP
cord-017161-lcqrd4v0	215	24	have	have	VBP
cord-017161-lcqrd4v0	215	25	different	different	JJ
cord-017161-lcqrd4v0	215	26	pathologic	pathologic	JJ
cord-017161-lcqrd4v0	215	27	effects	effect	NNS
cord-017161-lcqrd4v0	215	28	[	[	-LRB-
cord-017161-lcqrd4v0	215	29	118	118	CD
cord-017161-lcqrd4v0	215	30	]	]	-RRB-
cord-017161-lcqrd4v0	215	31	.	.	.
cord-017161-lcqrd4v0	216	1	For	for	IN
cord-017161-lcqrd4v0	216	2	example	example	NN
cord-017161-lcqrd4v0	216	3	,	,	,
cord-017161-lcqrd4v0	216	4	after	after	IN
cord-017161-lcqrd4v0	216	5	internalization	internalization	NN
cord-017161-lcqrd4v0	216	6	,	,	,
cord-017161-lcqrd4v0	216	7	PR3	pr3	NN
cord-017161-lcqrd4v0	216	8	causes	cause	VBZ
cord-017161-lcqrd4v0	216	9	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	216	10	cell	cell	NN
cord-017161-lcqrd4v0	216	11	apoptosis	apoptosis	NN
cord-017161-lcqrd4v0	216	12	,	,	,
cord-017161-lcqrd4v0	216	13	whereas	whereas	IN
cord-017161-lcqrd4v0	216	14	MPO	MPO	NNP
cord-017161-lcqrd4v0	216	15	causes	cause	VBZ
cord-017161-lcqrd4v0	216	16	generation	generation	NN
cord-017161-lcqrd4v0	216	17	of	of	IN
cord-017161-lcqrd4v0	216	18	intracellular	intracellular	JJ
cord-017161-lcqrd4v0	216	19	oxidants	oxidant	NNS
cord-017161-lcqrd4v0	216	20	[	[	-LRB-
cord-017161-lcqrd4v0	216	21	118	118	CD
cord-017161-lcqrd4v0	216	22	]	]	-RRB-
cord-017161-lcqrd4v0	216	23	.	.	.
cord-017161-lcqrd4v0	217	1	These	these	DT
cord-017161-lcqrd4v0	217	2	differences	difference	NNS
cord-017161-lcqrd4v0	217	3	in	in	IN
cord-017161-lcqrd4v0	217	4	MPO	MPO	NNP
cord-017161-lcqrd4v0	217	5	and	and	CC
cord-017161-lcqrd4v0	217	6	PR3	PR3	NNP
cord-017161-lcqrd4v0	217	7	interaction	interaction	NN
cord-017161-lcqrd4v0	217	8	with	with	IN
cord-017161-lcqrd4v0	217	9	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	217	10	cells	cell	NNS
cord-017161-lcqrd4v0	217	11	could	could	MD
cord-017161-lcqrd4v0	217	12	in	in	IN
cord-017161-lcqrd4v0	217	13	fl	fl	NNP
cord-017161-lcqrd4v0	217	14	uence	uence	NNP
cord-017161-lcqrd4v0	218	1	the	the	DT
cord-017161-lcqrd4v0	218	2	patterns	pattern	NNS
cord-017161-lcqrd4v0	218	3	of	of	IN
cord-017161-lcqrd4v0	218	4	tissue	tissue	NN
cord-017161-lcqrd4v0	218	5	injury	injury	NN
cord-017161-lcqrd4v0	218	6	induced	induce	VBN
cord-017161-lcqrd4v0	218	7	when	when	WRB
cord-017161-lcqrd4v0	218	8	these	these	DT
cord-017161-lcqrd4v0	218	9	antigens	antigen	NNS
cord-017161-lcqrd4v0	218	10	react	react	VBP
cord-017161-lcqrd4v0	218	11	with	with	IN
cord-017161-lcqrd4v0	218	12	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	218	13	at	at	IN
cord-017161-lcqrd4v0	218	14	the	the	DT
cord-017161-lcqrd4v0	218	15	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	218	16	cell	cell	NN
cord-017161-lcqrd4v0	218	17	surface	surface	NN
cord-017161-lcqrd4v0	218	18	[	[	-LRB-
cord-017161-lcqrd4v0	218	19	111	111	CD
cord-017161-lcqrd4v0	218	20	]	]	-RRB-
cord-017161-lcqrd4v0	218	21	.	.	.
cord-017161-lcqrd4v0	219	1	Furthermore	furthermore	RB
cord-017161-lcqrd4v0	219	2	,	,	,
cord-017161-lcqrd4v0	219	3	there	there	EX
cord-017161-lcqrd4v0	219	4	is	be	VBZ
cord-017161-lcqrd4v0	219	5	new	new	JJ
cord-017161-lcqrd4v0	219	6	evidence	evidence	NN
cord-017161-lcqrd4v0	219	7	that	that	IN
cord-017161-lcqrd4v0	219	8	after	after	IN
cord-017161-lcqrd4v0	219	9	neutrophil	neutrophil	NN
cord-017161-lcqrd4v0	219	10	activation	activation	NN
cord-017161-lcqrd4v0	219	11	by	by	IN
cord-017161-lcqrd4v0	219	12	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	219	13	,	,	,
cord-017161-lcqrd4v0	219	14	the	the	DT
cord-017161-lcqrd4v0	219	15	neutrophils	neutrophil	NNS
cord-017161-lcqrd4v0	219	16	are	be	VBP
cord-017161-lcqrd4v0	219	17	driven	drive	VBN
cord-017161-lcqrd4v0	219	18	down	down	RP
cord-017161-lcqrd4v0	219	19	an	an	DT
cord-017161-lcqrd4v0	219	20	accelerated	accelerated	JJ
cord-017161-lcqrd4v0	219	21	apoptotic	apoptotic	JJ
cord-017161-lcqrd4v0	219	22	death	death	NN
cord-017161-lcqrd4v0	219	23	pathway	pathway	NN
cord-017161-lcqrd4v0	219	24	by	by	IN
cord-017161-lcqrd4v0	219	25	reactive	reactive	JJ
cord-017161-lcqrd4v0	219	26	oxygen	oxygen	NN
cord-017161-lcqrd4v0	219	27	species	specie	NNS
cord-017161-lcqrd4v0	219	28	[	[	-LRB-
cord-017161-lcqrd4v0	219	29	119	119	CD
cord-017161-lcqrd4v0	219	30	]	]	-RRB-
cord-017161-lcqrd4v0	219	31	.	.	.
cord-017161-lcqrd4v0	220	1	These	these	DT
cord-017161-lcqrd4v0	220	2	neutrophils	neutrophil	NNS
cord-017161-lcqrd4v0	220	3	develop	develop	VBP
cord-017161-lcqrd4v0	220	4	the	the	DT
cord-017161-lcqrd4v0	220	5	morphologic	morphologic	JJ
cord-017161-lcqrd4v0	220	6	features	feature	NNS
cord-017161-lcqrd4v0	220	7	of	of	IN
cord-017161-lcqrd4v0	220	8	apoptosis	apoptosis	NN
cord-017161-lcqrd4v0	220	9	,	,	,
cord-017161-lcqrd4v0	220	10	but	but	CC
cord-017161-lcqrd4v0	220	11	there	there	EX
cord-017161-lcqrd4v0	220	12	is	be	VBZ
cord-017161-lcqrd4v0	220	13	dysregulated	dysregulate	VBN
cord-017161-lcqrd4v0	220	14	coordination	coordination	NN
cord-017161-lcqrd4v0	220	15	of	of	IN
cord-017161-lcqrd4v0	220	16	cell	cell	NN
cord-017161-lcqrd4v0	220	17	surface	surface	NN
cord-017161-lcqrd4v0	220	18	changes	change	NNS
cord-017161-lcqrd4v0	220	19	that	that	WDT
cord-017161-lcqrd4v0	220	20	normally	normally	RB
cord-017161-lcqrd4v0	220	21	accompany	accompany	VBP
cord-017161-lcqrd4v0	220	22	apoptosis	apoptosis	NN
cord-017161-lcqrd4v0	220	23	,	,	,
cord-017161-lcqrd4v0	220	24	including	include	VBG
cord-017161-lcqrd4v0	220	25	delay	delay	NN
cord-017161-lcqrd4v0	220	26	in	in	IN
cord-017161-lcqrd4v0	220	27	phosphatidylserine	phosphatidylserine	NN
cord-017161-lcqrd4v0	220	28	expression	expression	NN
cord-017161-lcqrd4v0	220	29	[	[	-LRB-
cord-017161-lcqrd4v0	220	30	119	119	CD
cord-017161-lcqrd4v0	220	31	]	]	-RRB-
cord-017161-lcqrd4v0	220	32	,	,	,
cord-017161-lcqrd4v0	220	33	which	which	WDT
cord-017161-lcqrd4v0	220	34	could	could	MD
cord-017161-lcqrd4v0	220	35	contribute	contribute	VB
cord-017161-lcqrd4v0	220	36	to	to	IN
cord-017161-lcqrd4v0	220	37	failure	failure	NN
cord-017161-lcqrd4v0	220	38	of	of	IN
cord-017161-lcqrd4v0	220	39	these	these	DT
cord-017161-lcqrd4v0	220	40	apoptotic	apoptotic	JJ
cord-017161-lcqrd4v0	220	41	cells	cell	NNS
cord-017161-lcqrd4v0	220	42	to	to	TO
cord-017161-lcqrd4v0	220	43	be	be	VB
cord-017161-lcqrd4v0	220	44	recognized	recognize	VBN
cord-017161-lcqrd4v0	220	45	and	and	CC
cord-017161-lcqrd4v0	220	46	safely	safely	RB
cord-017161-lcqrd4v0	220	47	removed	remove	VBN
cord-017161-lcqrd4v0	220	48	by	by	IN
cord-017161-lcqrd4v0	220	49	phagocytes	phagocyte	NNS
cord-017161-lcqrd4v0	220	50	[	[	-LRB-
cord-017161-lcqrd4v0	220	51	119	119	CD
cord-017161-lcqrd4v0	220	52	]	]	-RRB-
cord-017161-lcqrd4v0	220	53	.	.	.
cord-017161-lcqrd4v0	221	1	Apoptotic	apoptotic	JJ
cord-017161-lcqrd4v0	221	2	neutrophils	neutrophil	NNS
cord-017161-lcqrd4v0	221	3	eventually	eventually	RB
cord-017161-lcqrd4v0	221	4	disintegrate	disintegrate	VBP
cord-017161-lcqrd4v0	221	5	,	,	,
cord-017161-lcqrd4v0	221	6	releasing	release	VBG
cord-017161-lcqrd4v0	221	7	cytotoxic	cytotoxic	JJ
cord-017161-lcqrd4v0	221	8	contents	content	NNS
cord-017161-lcqrd4v0	221	9	within	within	IN
cord-017161-lcqrd4v0	221	10	vascular	vascular	JJ
cord-017161-lcqrd4v0	221	11	tissue	tissue	NN
cord-017161-lcqrd4v0	221	12	.	.	.
cord-017161-lcqrd4v0	222	1	This	this	DT
cord-017161-lcqrd4v0	222	2	process	process	NN
cord-017161-lcqrd4v0	222	3	may	may	MD
cord-017161-lcqrd4v0	222	4	explain	explain	VB
cord-017161-lcqrd4v0	222	5	the	the	DT
cord-017161-lcqrd4v0	222	6	leucocytoclasia	leucocytoclasia	NNP
cord-017161-lcqrd4v0	222	7	often	often	RB
cord-017161-lcqrd4v0	222	8	seen	see	VBN
cord-017161-lcqrd4v0	222	9	in	in	IN
cord-017161-lcqrd4v0	222	10	vasculitic	vasculitic	JJ
cord-017161-lcqrd4v0	222	11	lesions	lesion	NNS
cord-017161-lcqrd4v0	222	12	.	.	.
cord-017161-lcqrd4v0	223	1	Also	also	RB
cord-017161-lcqrd4v0	223	2	pertaining	pertain	VBG
cord-017161-lcqrd4v0	223	3	to	to	IN
cord-017161-lcqrd4v0	223	4	safe	safe	JJ
cord-017161-lcqrd4v0	223	5	clearance	clearance	NN
cord-017161-lcqrd4v0	223	6	of	of	IN
cord-017161-lcqrd4v0	223	7	apoptotic	apoptotic	JJ
cord-017161-lcqrd4v0	223	8	neutrophils	neutrophil	NNS
cord-017161-lcqrd4v0	223	9	are	be	VBP
cord-017161-lcqrd4v0	223	10	two	two	CD
cord-017161-lcqrd4v0	223	11	studies	study	NNS
cord-017161-lcqrd4v0	223	12	showing	show	VBG
cord-017161-lcqrd4v0	223	13	that	that	IN
cord-017161-lcqrd4v0	223	14	apoptotic	apoptotic	JJ
cord-017161-lcqrd4v0	223	15	neutrophils	neutrophil	NNS
cord-017161-lcqrd4v0	223	16	can	can	MD
cord-017161-lcqrd4v0	223	17	express	express	VB
cord-017161-lcqrd4v0	223	18	proteinase-3	proteinase-3	NNP
cord-017161-lcqrd4v0	223	19	and	and	CC
cord-017161-lcqrd4v0	223	20	myeloperoxidase	myeloperoxidase	NN
cord-017161-lcqrd4v0	223	21	at	at	IN
cord-017161-lcqrd4v0	223	22	the	the	DT
cord-017161-lcqrd4v0	223	23	cell	cell	NN
cord-017161-lcqrd4v0	223	24	surface	surface	NN
cord-017161-lcqrd4v0	223	25	,	,	,
cord-017161-lcqrd4v0	223	26	which	which	WDT
cord-017161-lcqrd4v0	223	27	can	can	MD
cord-017161-lcqrd4v0	223	28	act	act	VB
cord-017161-lcqrd4v0	223	29	as	as	IN
cord-017161-lcqrd4v0	223	30	an	an	DT
cord-017161-lcqrd4v0	223	31	opsonin	opsonin	NN
cord-017161-lcqrd4v0	223	32	for	for	IN
cord-017161-lcqrd4v0	223	33	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	223	34	[	[	-LRB-
cord-017161-lcqrd4v0	223	35	120	120	CD
cord-017161-lcqrd4v0	223	36	,	,	,
cord-017161-lcqrd4v0	223	37	121	121	CD
cord-017161-lcqrd4v0	223	38	]	]	-RRB-
cord-017161-lcqrd4v0	223	39	.	.	.
cord-017161-lcqrd4v0	224	1	Both	both	DT
cord-017161-lcqrd4v0	224	2	apoptotic	apoptotic	JJ
cord-017161-lcqrd4v0	224	3	and	and	CC
cord-017161-lcqrd4v0	224	4	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	224	5	opsonized	opsonize	VBD
cord-017161-lcqrd4v0	224	6	apoptotic	apoptotic	JJ
cord-017161-lcqrd4v0	224	7	neutrophils	neutrophil	NNS
cord-017161-lcqrd4v0	224	8	can	can	MD
cord-017161-lcqrd4v0	224	9	be	be	VB
cord-017161-lcqrd4v0	224	10	phagocytosed	phagocytose	VBN
cord-017161-lcqrd4v0	224	11	by	by	IN
cord-017161-lcqrd4v0	224	12	macrophages	macrophage	NNS
cord-017161-lcqrd4v0	224	13	,	,	,
cord-017161-lcqrd4v0	224	14	but	but	CC
cord-017161-lcqrd4v0	224	15	whereas	whereas	IN
cord-017161-lcqrd4v0	224	16	the	the	DT
cord-017161-lcqrd4v0	224	17	former	former	JJ
cord-017161-lcqrd4v0	224	18	induce	induce	VBP
cord-017161-lcqrd4v0	224	19	an	an	DT
cord-017161-lcqrd4v0	224	20	anti	anti	JJ
cord-017161-lcqrd4v0	224	21	-	-	NN
cord-017161-lcqrd4v0	224	22	in	in	IN
cord-017161-lcqrd4v0	224	23	fl	fl	NNP
cord-017161-lcqrd4v0	224	24	ammatory	ammatory	NNP
cord-017161-lcqrd4v0	224	25	response	response	NN
cord-017161-lcqrd4v0	224	26	from	from	IN
cord-017161-lcqrd4v0	224	27	the	the	DT
cord-017161-lcqrd4v0	224	28	macrophage	macrophage	NN
cord-017161-lcqrd4v0	224	29	release	release	NN
cord-017161-lcqrd4v0	224	30	of	of	IN
cord-017161-lcqrd4v0	224	31	interleukin-10	interleukin-10	NN
cord-017161-lcqrd4v0	224	32	,	,	,
cord-017161-lcqrd4v0	224	33	the	the	DT
cord-017161-lcqrd4v0	224	34	latter	latter	JJ
cord-017161-lcqrd4v0	224	35	are	be	VBP
cord-017161-lcqrd4v0	224	36	taken	take	VBN
cord-017161-lcqrd4v0	224	37	up	up	RP
cord-017161-lcqrd4v0	224	38	more	more	RBR
cord-017161-lcqrd4v0	224	39	avidly	avidly	RB
cord-017161-lcqrd4v0	224	40	and	and	CC
cord-017161-lcqrd4v0	224	41	are	be	VBP
cord-017161-lcqrd4v0	224	42	proin	proin	NNP
cord-017161-lcqrd4v0	224	43	fl	fl	NNP
cord-017161-lcqrd4v0	224	44	ammatory	ammatory	NNP
cord-017161-lcqrd4v0	224	45	by	by	IN
cord-017161-lcqrd4v0	224	46	inducing	induce	VBG
cord-017161-lcqrd4v0	224	47	macrophage	macrophage	NN
cord-017161-lcqrd4v0	224	48	release	release	NN
cord-017161-lcqrd4v0	224	49	of	of	IN
cord-017161-lcqrd4v0	224	50	interleukin-1	interleukin-1	NN
cord-017161-lcqrd4v0	224	51	,	,	,
cord-017161-lcqrd4v0	224	52	interleukin-8	interleukin-8	NNP
cord-017161-lcqrd4v0	224	53	and	and	CC
cord-017161-lcqrd4v0	224	54	TNF	TNF	NNP
cord-017161-lcqrd4v0	224	55	[	[	-LRB-
cord-017161-lcqrd4v0	224	56	120	120	CD
cord-017161-lcqrd4v0	224	57	,	,	,
cord-017161-lcqrd4v0	224	58	121	121	CD
cord-017161-lcqrd4v0	224	59	]	]	-RRB-
cord-017161-lcqrd4v0	224	60	.	.	.
cord-017161-lcqrd4v0	225	1	The	the	DT
cord-017161-lcqrd4v0	225	2	signalling	signal	VBG
cord-017161-lcqrd4v0	225	3	cascades	cascade	NNS
cord-017161-lcqrd4v0	225	4	that	that	WDT
cord-017161-lcqrd4v0	225	5	lead	lead	VBP
cord-017161-lcqrd4v0	225	6	to	to	IN
cord-017161-lcqrd4v0	225	7	functional	functional	JJ
cord-017161-lcqrd4v0	225	8	responses	response	NNS
cord-017161-lcqrd4v0	225	9	such	such	JJ
cord-017161-lcqrd4v0	225	10	as	as	IN
cord-017161-lcqrd4v0	225	11	superoxide	superoxide	NN
cord-017161-lcqrd4v0	225	12	release	release	NN
cord-017161-lcqrd4v0	225	13	are	be	VBP
cord-017161-lcqrd4v0	225	14	only	only	RB
cord-017161-lcqrd4v0	225	15	beginning	begin	VBG
cord-017161-lcqrd4v0	225	16	to	to	TO
cord-017161-lcqrd4v0	225	17	be	be	VB
cord-017161-lcqrd4v0	225	18	elucidated	elucidate	VBN
cord-017161-lcqrd4v0	225	19	.	.	.
cord-017161-lcqrd4v0	226	1	Tyrosine	tyrosine	NN
cord-017161-lcqrd4v0	226	2	kinases	kinase	NNS
cord-017161-lcqrd4v0	226	3	and	and	CC
cord-017161-lcqrd4v0	226	4	protein	protein	NN
cord-017161-lcqrd4v0	226	5	kinase	kinase	NN
cord-017161-lcqrd4v0	226	6	C	C	NNP
cord-017161-lcqrd4v0	226	7	are	be	VBP
cord-017161-lcqrd4v0	226	8	known	know	VBN
cord-017161-lcqrd4v0	226	9	to	to	TO
cord-017161-lcqrd4v0	226	10	be	be	VB
cord-017161-lcqrd4v0	226	11	involved	involve	VBN
cord-017161-lcqrd4v0	226	12	[	[	-LRB-
cord-017161-lcqrd4v0	226	13	122	122	CD
cord-017161-lcqrd4v0	226	14	]	]	-RRB-
cord-017161-lcqrd4v0	226	15	.	.	.
cord-017161-lcqrd4v0	227	1	Now	now	RB
cord-017161-lcqrd4v0	227	2	,	,	,
cord-017161-lcqrd4v0	227	3	mitogen	mitogen	NN
cord-017161-lcqrd4v0	227	4	-	-	HYPH
cord-017161-lcqrd4v0	227	5	activated	activate	VBN
cord-017161-lcqrd4v0	227	6	protein	protein	NN
cord-017161-lcqrd4v0	227	7	kinases	kinase	NNS
cord-017161-lcqrd4v0	227	8	that	that	WDT
cord-017161-lcqrd4v0	227	9	require	require	VBP
cord-017161-lcqrd4v0	227	10	tyrosine	tyrosine	NN
cord-017161-lcqrd4v0	227	11	phosphorylation	phosphorylation	NN
cord-017161-lcqrd4v0	227	12	for	for	IN
cord-017161-lcqrd4v0	227	13	activation	activation	NN
cord-017161-lcqrd4v0	227	14	also	also	RB
cord-017161-lcqrd4v0	227	15	have	have	VBP
cord-017161-lcqrd4v0	227	16	been	be	VBN
cord-017161-lcqrd4v0	227	17	implicated	implicate	VBN
cord-017161-lcqrd4v0	227	18	,	,	,
cord-017161-lcqrd4v0	227	19	particularly	particularly	RB
cord-017161-lcqrd4v0	227	20	in	in	IN
cord-017161-lcqrd4v0	227	21	TNF	TNF	NNP
cord-017161-lcqrd4v0	227	22	-	-	HYPH
cord-017161-lcqrd4v0	227	23	mediated	mediate	VBN
cord-017161-lcqrd4v0	227	24	priming	priming	NN
cord-017161-lcqrd4v0	227	25	[	[	-LRB-
cord-017161-lcqrd4v0	227	26	123	123	CD
cord-017161-lcqrd4v0	227	27	]	]	-RRB-
cord-017161-lcqrd4v0	227	28	.	.	.
cord-017161-lcqrd4v0	228	1	Furthermore	furthermore	RB
cord-017161-lcqrd4v0	228	2	,	,	,
cord-017161-lcqrd4v0	228	3	in	in	IN
cord-017161-lcqrd4v0	228	4	WG	WG	NNP
cord-017161-lcqrd4v0	228	5	the	the	DT
cord-017161-lcqrd4v0	228	6	granulomatous	granulomatous	JJ
cord-017161-lcqrd4v0	228	7	in	in	IN
cord-017161-lcqrd4v0	228	8	fl	fl	NNP
cord-017161-lcqrd4v0	228	9	ammation	ammation	NNP
cord-017161-lcqrd4v0	228	10	displays	display	VBZ
cord-017161-lcqrd4v0	228	11	several	several	JJ
cord-017161-lcqrd4v0	228	12	different	different	JJ
cord-017161-lcqrd4v0	228	13	morphologies	morphology	NNS
cord-017161-lcqrd4v0	228	14	.	.	.
cord-017161-lcqrd4v0	229	1	Within	within	IN
cord-017161-lcqrd4v0	229	2	a	a	DT
cord-017161-lcqrd4v0	229	3	surrounding	surrounding	NN
cord-017161-lcqrd4v0	229	4	in	in	IN
cord-017161-lcqrd4v0	229	5	fl	fl	NNP
cord-017161-lcqrd4v0	229	6	ammatory	ammatory	NNP
cord-017161-lcqrd4v0	229	7	background	background	NN
cord-017161-lcqrd4v0	229	8	,	,	,
cord-017161-lcqrd4v0	229	9	poorly	poorly	RB
cord-017161-lcqrd4v0	229	10	formed	form	VBN
cord-017161-lcqrd4v0	229	11	epithelioid	epithelioid	JJ
cord-017161-lcqrd4v0	229	12	cell	cell	NN
cord-017161-lcqrd4v0	229	13	granulomas	granuloma	NNS
cord-017161-lcqrd4v0	229	14	,	,	,
cord-017161-lcqrd4v0	230	1	scattered	scatter	VBN
cord-017161-lcqrd4v0	230	2	histiocytic	histiocytic	JJ
cord-017161-lcqrd4v0	230	3	giant	giant	JJ
cord-017161-lcqrd4v0	230	4	cells	cell	NNS
cord-017161-lcqrd4v0	230	5	of	of	IN
cord-017161-lcqrd4v0	230	6	Langhans	Langhans	NNP
cord-017161-lcqrd4v0	230	7	type	type	NN
cord-017161-lcqrd4v0	230	8	or	or	CC
cord-017161-lcqrd4v0	230	9	palisading	palisade	VBG
cord-017161-lcqrd4v0	230	10	histiocytes	histiocyte	NNS
cord-017161-lcqrd4v0	230	11	around	around	IN
cord-017161-lcqrd4v0	230	12	central	central	JJ
cord-017161-lcqrd4v0	230	13	necrosis	necrosis	NN
cord-017161-lcqrd4v0	230	14	may	may	MD
cord-017161-lcqrd4v0	230	15	be	be	VB
cord-017161-lcqrd4v0	230	16	seen	see	VBN
cord-017161-lcqrd4v0	230	17	[	[	-LRB-
cord-017161-lcqrd4v0	230	18	124	124	CD
cord-017161-lcqrd4v0	230	19	]	]	-RRB-
cord-017161-lcqrd4v0	230	20	.	.	.
cord-017161-lcqrd4v0	231	1	The	the	DT
cord-017161-lcqrd4v0	231	2	mixed	mixed	JJ
cord-017161-lcqrd4v0	231	3	in	in	IN
cord-017161-lcqrd4v0	231	4	fl	fl	NNP
cord-017161-lcqrd4v0	231	5	ammatory	ammatory	NNP
cord-017161-lcqrd4v0	231	6	in	in	IN
cord-017161-lcqrd4v0	231	7	fi	fi	NNP
cord-017161-lcqrd4v0	231	8	ltrate	ltrate	NNP
cord-017161-lcqrd4v0	231	9	in	in	IN
cord-017161-lcqrd4v0	231	10	WG	WG	NNP
cord-017161-lcqrd4v0	231	11	is	be	VBZ
cord-017161-lcqrd4v0	231	12	composed	compose	VBN
cord-017161-lcqrd4v0	231	13	of	of	IN
cord-017161-lcqrd4v0	231	14	lymphocytes	lymphocyte	NNS
cord-017161-lcqrd4v0	231	15	,	,	,
cord-017161-lcqrd4v0	231	16	plasma	plasma	NN
cord-017161-lcqrd4v0	231	17	cells	cell	NNS
cord-017161-lcqrd4v0	231	18	,	,	,
cord-017161-lcqrd4v0	231	19	neutrophils	neutrophil	NNS
cord-017161-lcqrd4v0	231	20	,	,	,
cord-017161-lcqrd4v0	231	21	eosinophils	eosinophil	NNS
cord-017161-lcqrd4v0	231	22	,	,	,
cord-017161-lcqrd4v0	231	23	monocytes	monocyte	NNS
cord-017161-lcqrd4v0	231	24	,	,	,
cord-017161-lcqrd4v0	231	25	macrophages	macrophage	NNS
cord-017161-lcqrd4v0	231	26	,	,	,
cord-017161-lcqrd4v0	231	27	histiocytes	histiocyte	NNS
cord-017161-lcqrd4v0	231	28	and	and	CC
cord-017161-lcqrd4v0	231	29	giant	giant	JJ
cord-017161-lcqrd4v0	231	30	cells	cell	NNS
cord-017161-lcqrd4v0	231	31	[	[	-LRB-
cord-017161-lcqrd4v0	231	32	124	124	CD
cord-017161-lcqrd4v0	231	33	]	]	-RRB-
cord-017161-lcqrd4v0	231	34	.	.	.
cord-017161-lcqrd4v0	232	1	Since	since	IN
cord-017161-lcqrd4v0	232	2	INF	INF	NNP
cord-017161-lcqrd4v0	232	3	-	-	HYPH
cord-017161-lcqrd4v0	232	4	g	g	NN
cord-017161-lcqrd4v0	232	5	and	and	CC
cord-017161-lcqrd4v0	232	6	T	t	NN
cord-017161-lcqrd4v0	232	7	cells	cell	NNS
cord-017161-lcqrd4v0	232	8	play	play	VBP
cord-017161-lcqrd4v0	232	9	pivotal	pivotal	JJ
cord-017161-lcqrd4v0	232	10	roles	role	NNS
cord-017161-lcqrd4v0	232	11	in	in	IN
cord-017161-lcqrd4v0	232	12	granuloma	granuloma	NN
cord-017161-lcqrd4v0	232	13	formation	formation	NN
cord-017161-lcqrd4v0	232	14	,	,	,
cord-017161-lcqrd4v0	232	15	alterations	alteration	NNS
cord-017161-lcqrd4v0	232	16	of	of	IN
cord-017161-lcqrd4v0	232	17	the	the	DT
cord-017161-lcqrd4v0	232	18	T	t	NN
cord-017161-lcqrd4v0	232	19	-	-	HYPH
cord-017161-lcqrd4v0	232	20	cell	cell	NN
cord-017161-lcqrd4v0	232	21	and	and	CC
cord-017161-lcqrd4v0	232	22	cytokine	cytokine	NN
cord-017161-lcqrd4v0	232	23	response	response	NN
cord-017161-lcqrd4v0	232	24	could	could	MD
cord-017161-lcqrd4v0	232	25	contribute	contribute	VB
cord-017161-lcqrd4v0	232	26	to	to	IN
cord-017161-lcqrd4v0	232	27	anomalous	anomalous	JJ
cord-017161-lcqrd4v0	232	28	autoantigen	autoantigen	NN
cord-017161-lcqrd4v0	232	29	presentation	presentation	NN
cord-017161-lcqrd4v0	232	30	in	in	IN
cord-017161-lcqrd4v0	232	31	ectopic	ectopic	JJ
cord-017161-lcqrd4v0	232	32	lymphoid	lymphoid	JJ
cord-017161-lcqrd4v0	232	33	-	-	HYPH
cord-017161-lcqrd4v0	232	34	like	like	JJ
cord-017161-lcqrd4v0	232	35	structures	structure	NNS
cord-017161-lcqrd4v0	232	36	and	and	CC
cord-017161-lcqrd4v0	232	37	sustain	sustain	VB
cord-017161-lcqrd4v0	232	38	autoimmunity	autoimmunity	NN
cord-017161-lcqrd4v0	232	39	to	to	IN
cord-017161-lcqrd4v0	232	40	PR3	PR3	NNP
cord-017161-lcqrd4v0	232	41	[	[	-LRB-
cord-017161-lcqrd4v0	232	42	125	125	CD
cord-017161-lcqrd4v0	232	43	]	]	-RRB-
cord-017161-lcqrd4v0	232	44	.	.	.
cord-017161-lcqrd4v0	233	1	Skewing	skew	VBG
cord-017161-lcqrd4v0	233	2	of	of	IN
cord-017161-lcqrd4v0	233	3	the	the	DT
cord-017161-lcqrd4v0	233	4	T	t	NN
cord-017161-lcqrd4v0	233	5	-	-	HYPH
cord-017161-lcqrd4v0	233	6	cell	cell	NN
cord-017161-lcqrd4v0	233	7	phenotype	phenotype	NN
cord-017161-lcqrd4v0	233	8	with	with	IN
cord-017161-lcqrd4v0	233	9	expansion	expansion	NN
cord-017161-lcqrd4v0	233	10	of	of	IN
cord-017161-lcqrd4v0	233	11	the	the	DT
cord-017161-lcqrd4v0	233	12	CD4	CD4	NNP
cord-017161-lcqrd4v0	233	13	+	+	CC
cord-017161-lcqrd4v0	233	14	and	and	CC
cord-017161-lcqrd4v0	233	15	CD8	CD8	NNP
cord-017161-lcqrd4v0	233	16	+	+	CC
cord-017161-lcqrd4v0	233	17	T	T	NNP
cord-017161-lcqrd4v0	233	18	cells	cell	NNS
cord-017161-lcqrd4v0	233	19	lacking	lack	VBG
cord-017161-lcqrd4v0	233	20	CD28	CD28	NNP
cord-017161-lcqrd4v0	233	21	expression	expression	NN
cord-017161-lcqrd4v0	233	22	is	be	VBZ
cord-017161-lcqrd4v0	233	23	seen	see	VBN
cord-017161-lcqrd4v0	233	24	in	in	IN
cord-017161-lcqrd4v0	233	25	WG	WG	NNP
cord-017161-lcqrd4v0	233	26	[	[	-LRB-
cord-017161-lcqrd4v0	233	27	126	126	CD
cord-017161-lcqrd4v0	233	28	,	,	,
cord-017161-lcqrd4v0	233	29	127	127	CD
cord-017161-lcqrd4v0	233	30	]	]	-RRB-
cord-017161-lcqrd4v0	233	31	.	.	.
cord-017161-lcqrd4v0	234	1	Expansion	expansion	NN
cord-017161-lcqrd4v0	234	2	of	of	IN
cord-017161-lcqrd4v0	234	3	CD28	CD28	NNP
cord-017161-lcqrd4v0	234	4	negative	negative	JJ
cord-017161-lcqrd4v0	234	5	T	t	NN
cord-017161-lcqrd4v0	234	6	cells	cell	NNS
cord-017161-lcqrd4v0	234	7	is	be	VBZ
cord-017161-lcqrd4v0	234	8	already	already	RB
cord-017161-lcqrd4v0	234	9	evident	evident	JJ
cord-017161-lcqrd4v0	234	10	in	in	IN
cord-017161-lcqrd4v0	234	11	localized	localize	VBN
cord-017161-lcqrd4v0	234	12	WG	WG	NNP
cord-017161-lcqrd4v0	234	13	and	and	CC
cord-017161-lcqrd4v0	234	14	further	further	JJ
cord-017161-lcqrd4v0	234	15	increases	increase	NNS
cord-017161-lcqrd4v0	234	16	in	in	IN
cord-017161-lcqrd4v0	234	17	generalized	generalized	JJ
cord-017161-lcqrd4v0	234	18	disease	disease	NN
cord-017161-lcqrd4v0	234	19	[	[	-LRB-
cord-017161-lcqrd4v0	234	20	126	126	CD
cord-017161-lcqrd4v0	234	21	,	,	,
cord-017161-lcqrd4v0	234	22	127	127	CD
cord-017161-lcqrd4v0	234	23	]	]	-RRB-
cord-017161-lcqrd4v0	234	24	.	.	.
cord-017161-lcqrd4v0	235	1	Abundant	abundant	JJ
cord-017161-lcqrd4v0	235	2	IFN	IFN	NNP
cord-017161-lcqrd4v0	235	3	-	-	HYPH
cord-017161-lcqrd4v0	235	4	g	g	NNP
cord-017161-lcqrd4v0	235	5	,	,	,
cord-017161-lcqrd4v0	235	6	CD26	CD26	NNP
cord-017161-lcqrd4v0	235	7	and	and	CC
cord-017161-lcqrd4v0	235	8	Th-1	Th-1	NNP
cord-017161-lcqrd4v0	235	9	type	type	NN
cord-017161-lcqrd4v0	235	10	CC	CC	NNP
cord-017161-lcqrd4v0	235	11	chemokine	chemokine	NN
cord-017161-lcqrd4v0	235	12	receptor	receptor	NN
cord-017161-lcqrd4v0	235	13	CCR5	CCR5	NNP
cord-017161-lcqrd4v0	235	14	expression	expression	NN
cord-017161-lcqrd4v0	235	15	are	be	VBP
cord-017161-lcqrd4v0	235	16	seen	see	VBN
cord-017161-lcqrd4v0	235	17	in	in	IN
cord-017161-lcqrd4v0	235	18	granulomatous	granulomatous	JJ
cord-017161-lcqrd4v0	235	19	lesions	lesion	NNS
cord-017161-lcqrd4v0	235	20	of	of	IN
cord-017161-lcqrd4v0	235	21	the	the	DT
cord-017161-lcqrd4v0	235	22	respiratory	respiratory	JJ
cord-017161-lcqrd4v0	235	23	tract	tract	NN
cord-017161-lcqrd4v0	235	24	in	in	IN
cord-017161-lcqrd4v0	235	25	localized	localize	VBN
cord-017161-lcqrd4v0	235	26	WG	WG	NNP
cord-017161-lcqrd4v0	235	27	,	,	,
cord-017161-lcqrd4v0	235	28	but	but	CC
cord-017161-lcqrd4v0	235	29	appear	appear	VBP
cord-017161-lcqrd4v0	235	30	less	less	RBR
cord-017161-lcqrd4v0	235	31	strong	strong	JJ
cord-017161-lcqrd4v0	235	32	in	in	IN
cord-017161-lcqrd4v0	235	33	generalized	generalized	JJ
cord-017161-lcqrd4v0	235	34	WG	WG	NNP
cord-017161-lcqrd4v0	235	35	[	[	-LRB-
cord-017161-lcqrd4v0	235	36	128	128	CD
cord-017161-lcqrd4v0	235	37	,	,	,
cord-017161-lcqrd4v0	235	38	129	129	CD
cord-017161-lcqrd4v0	235	39	]	]	-RRB-
cord-017161-lcqrd4v0	235	40	.	.	.
cord-017161-lcqrd4v0	236	1	Moreover	moreover	RB
cord-017161-lcqrd4v0	236	2	,	,	,
cord-017161-lcqrd4v0	236	3	a	a	DT
cord-017161-lcqrd4v0	236	4	fraction	fraction	NN
cord-017161-lcqrd4v0	236	5	of	of	IN
cord-017161-lcqrd4v0	236	6	Th2	th2	CD
cord-017161-lcqrd4v0	236	7	type	type	NN
cord-017161-lcqrd4v0	236	8	IL-4	IL-4	NNP
cord-017161-lcqrd4v0	236	9	producing	produce	VBG
cord-017161-lcqrd4v0	236	10	CCR3	CCR3	NNP
cord-017161-lcqrd4v0	237	1	+	+	CC
cord-017161-lcqrd4v0	237	2	T	t	NN
cord-017161-lcqrd4v0	237	3	cells	cell	NNS
cord-017161-lcqrd4v0	237	4	is	be	VBZ
cord-017161-lcqrd4v0	237	5	present	present	JJ
cord-017161-lcqrd4v0	237	6	in	in	IN
cord-017161-lcqrd4v0	237	7	the	the	DT
cord-017161-lcqrd4v0	237	8	circulation	circulation	NN
cord-017161-lcqrd4v0	237	9	and	and	CC
cord-017161-lcqrd4v0	237	10	tissue	tissue	NN
cord-017161-lcqrd4v0	237	11	lesions	lesion	NNS
cord-017161-lcqrd4v0	237	12	in	in	IN
cord-017161-lcqrd4v0	237	13	generalized	generalized	JJ
cord-017161-lcqrd4v0	237	14	but	but	CC
cord-017161-lcqrd4v0	237	15	not	not	RB
cord-017161-lcqrd4v0	237	16	in	in	IN
cord-017161-lcqrd4v0	237	17	localized	localize	VBN
cord-017161-lcqrd4v0	237	18	WG	WG	NNP
cord-017161-lcqrd4v0	237	19	[	[	-LRB-
cord-017161-lcqrd4v0	237	20	128	128	CD
cord-017161-lcqrd4v0	237	21	]	]	-RRB-
cord-017161-lcqrd4v0	237	22	.	.	.
cord-017161-lcqrd4v0	238	1	These	these	DT
cord-017161-lcqrd4v0	238	2	data	datum	NNS
cord-017161-lcqrd4v0	238	3	suggest	suggest	VBP
cord-017161-lcqrd4v0	238	4	that	that	IN
cord-017161-lcqrd4v0	238	5	an	an	DT
cord-017161-lcqrd4v0	238	6	aberrant	aberrant	JJ
cord-017161-lcqrd4v0	238	7	Th-1	Th-1	NNP
cord-017161-lcqrd4v0	238	8	type	type	NN
cord-017161-lcqrd4v0	238	9	response	response	NN
cord-017161-lcqrd4v0	238	10	favouring	favour	VBG
cord-017161-lcqrd4v0	238	11	granuloma	granuloma	NN
cord-017161-lcqrd4v0	238	12	formation	formation	NN
cord-017161-lcqrd4v0	238	13	might	may	MD
cord-017161-lcqrd4v0	238	14	play	play	VB
cord-017161-lcqrd4v0	238	15	a	a	DT
cord-017161-lcqrd4v0	238	16	role	role	NN
cord-017161-lcqrd4v0	238	17	in	in	IN
cord-017161-lcqrd4v0	238	18	initiation	initiation	NN
cord-017161-lcqrd4v0	238	19	of	of	IN
cord-017161-lcqrd4v0	238	20	WG	WG	NNP
cord-017161-lcqrd4v0	238	21	[	[	-LRB-
cord-017161-lcqrd4v0	238	22	130	130	CD
cord-017161-lcqrd4v0	238	23	]	]	-RRB-
cord-017161-lcqrd4v0	238	24	.	.	.
cord-017161-lcqrd4v0	239	1	Ectopic	ectopic	JJ
cord-017161-lcqrd4v0	239	2	presentation	presentation	NN
cord-017161-lcqrd4v0	239	3	of	of	IN
cord-017161-lcqrd4v0	239	4	the	the	DT
cord-017161-lcqrd4v0	239	5	Wegener	Wegener	NNP
cord-017161-lcqrd4v0	239	6	's	's	POS
cord-017161-lcqrd4v0	239	7	autoantigen	autoantigen	NN
cord-017161-lcqrd4v0	239	8	PR3	PR3	NNP
cord-017161-lcqrd4v0	239	9	and	and	CC
cord-017161-lcqrd4v0	239	10	autoimmunity	autoimmunity	NN
cord-017161-lcqrd4v0	239	11	to	to	IN
cord-017161-lcqrd4v0	239	12	PR3	PR3	NNP
cord-017161-lcqrd4v0	239	13	might	may	MD
cord-017161-lcqrd4v0	239	14	be	be	VB
cord-017161-lcqrd4v0	239	15	sustained	sustain	VBN
cord-017161-lcqrd4v0	239	16	within	within	RB
cord-017161-lcqrd4v0	239	17	in	in	IN
cord-017161-lcqrd4v0	239	18	fl	fl	NNP
cord-017161-lcqrd4v0	239	19	ammatory	ammatory	NNP
cord-017161-lcqrd4v0	239	20	lesions	lesion	NNS
cord-017161-lcqrd4v0	239	21	and	and	CC
cord-017161-lcqrd4v0	239	22	by	by	IN
cord-017161-lcqrd4v0	239	23	skewed	skewed	JJ
cord-017161-lcqrd4v0	239	24	T	t	NN
cord-017161-lcqrd4v0	239	25	-	-	HYPH
cord-017161-lcqrd4v0	239	26	cell	cell	NN
cord-017161-lcqrd4v0	239	27	and	and	CC
cord-017161-lcqrd4v0	239	28	cytokine	cytokine	NN
cord-017161-lcqrd4v0	239	29	responses	response	NNS
cord-017161-lcqrd4v0	239	30	[	[	-LRB-
cord-017161-lcqrd4v0	239	31	130	130	CD
cord-017161-lcqrd4v0	239	32	]	]	-RRB-
cord-017161-lcqrd4v0	239	33	.	.	.
cord-017161-lcqrd4v0	240	1	Progression	progression	NN
cord-017161-lcqrd4v0	240	2	from	from	IN
cord-017161-lcqrd4v0	240	3	localized	localize	VBN
cord-017161-lcqrd4v0	240	4	to	to	IN
cord-017161-lcqrd4v0	240	5	generalized	generalize	VBN
cord-017161-lcqrd4v0	240	6	WG	WG	NNP
cord-017161-lcqrd4v0	240	7	is	be	VBZ
cord-017161-lcqrd4v0	240	8	associated	associate	VBN
cord-017161-lcqrd4v0	240	9	with	with	IN
cord-017161-lcqrd4v0	240	10	the	the	DT
cord-017161-lcqrd4v0	240	11	appearance	appearance	NN
cord-017161-lcqrd4v0	240	12	of	of	IN
cord-017161-lcqrd4v0	240	13	another	another	DT
cord-017161-lcqrd4v0	240	14	subset	subset	NN
cord-017161-lcqrd4v0	240	15	of	of	IN
cord-017161-lcqrd4v0	240	16	Th-2	Th-2	NNP
cord-017161-lcqrd4v0	240	17	type	type	NN
cord-017161-lcqrd4v0	240	18	cells	cell	NNS
cord-017161-lcqrd4v0	240	19	,	,	,
cord-017161-lcqrd4v0	240	20	which	which	WDT
cord-017161-lcqrd4v0	240	21	could	could	MD
cord-017161-lcqrd4v0	240	22	be	be	VB
cord-017161-lcqrd4v0	240	23	a	a	DT
cord-017161-lcqrd4v0	240	24	consequence	consequence	NN
cord-017161-lcqrd4v0	240	25	of	of	IN
cord-017161-lcqrd4v0	240	26	B	b	NN
cord-017161-lcqrd4v0	240	27	-	-	HYPH
cord-017161-lcqrd4v0	240	28	cell	cell	NN
cord-017161-lcqrd4v0	240	29	expansion	expansion	NN
cord-017161-lcqrd4v0	240	30	and	and	CC
cord-017161-lcqrd4v0	240	31	T	t	NN
cord-017161-lcqrd4v0	240	32	-	-	HYPH
cord-017161-lcqrd4v0	240	33	cell	cell	NN
cord-017161-lcqrd4v0	240	34	-	-	HYPH
cord-017161-lcqrd4v0	240	35	dependent	dependent	JJ
cord-017161-lcqrd4v0	240	36	PR-3	PR-3	NNP
cord-017161-lcqrd4v0	240	37	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	240	38	production	production	NN
cord-017161-lcqrd4v0	240	39	during	during	IN
cord-017161-lcqrd4v0	240	40	disease	disease	NN
cord-017161-lcqrd4v0	240	41	progression	progression	NN
cord-017161-lcqrd4v0	240	42	[	[	-LRB-
cord-017161-lcqrd4v0	240	43	130	130	CD
cord-017161-lcqrd4v0	240	44	]	]	-RRB-
cord-017161-lcqrd4v0	240	45	.	.	.
cord-017161-lcqrd4v0	241	1	In	in	IN
cord-017161-lcqrd4v0	241	2	addition	addition	NN
cord-017161-lcqrd4v0	241	3	,	,	,
cord-017161-lcqrd4v0	241	4	Th17	th17	NN
cord-017161-lcqrd4v0	241	5	cells	cell	NNS
cord-017161-lcqrd4v0	241	6	have	have	VBP
cord-017161-lcqrd4v0	241	7	been	be	VBN
cord-017161-lcqrd4v0	241	8	recently	recently	RB
cord-017161-lcqrd4v0	241	9	described	describe	VBN
cord-017161-lcqrd4v0	241	10	as	as	IN
cord-017161-lcqrd4v0	241	11	major	major	JJ
cord-017161-lcqrd4v0	241	12	effector	effector	NN
cord-017161-lcqrd4v0	241	13	cells	cell	NNS
cord-017161-lcqrd4v0	241	14	in	in	IN
cord-017161-lcqrd4v0	241	15	autoimmune	autoimmune	JJ
cord-017161-lcqrd4v0	241	16	diseases	disease	NNS
cord-017161-lcqrd4v0	241	17	[	[	-LRB-
cord-017161-lcqrd4v0	241	18	131	131	CD
cord-017161-lcqrd4v0	241	19	]	]	-RRB-
cord-017161-lcqrd4v0	241	20	.	.	.
cord-017161-lcqrd4v0	242	1	It	-PRON-	PRP
cord-017161-lcqrd4v0	242	2	has	have	VBZ
cord-017161-lcqrd4v0	242	3	been	be	VBN
cord-017161-lcqrd4v0	242	4	demonstrated	demonstrate	VBN
cord-017161-lcqrd4v0	242	5	that	that	IN
cord-017161-lcqrd4v0	242	6	stimulation	stimulation	NN
cord-017161-lcqrd4v0	242	7	of	of	IN
cord-017161-lcqrd4v0	242	8	peripheral	peripheral	JJ
cord-017161-lcqrd4v0	242	9	blood	blood	NN
cord-017161-lcqrd4v0	242	10	mononuclear	mononuclear	NN
cord-017161-lcqrd4v0	242	11	cells	cell	NNS
cord-017161-lcqrd4v0	242	12	from	from	IN
cord-017161-lcqrd4v0	242	13	PR3-ANCA	PR3-ANCA	NNP
cord-017161-lcqrd4v0	242	14	positive	positive	JJ
cord-017161-lcqrd4v0	242	15	patients	patient	NNS
cord-017161-lcqrd4v0	242	16	with	with	IN
cord-017161-lcqrd4v0	242	17	WG	WG	NNP
cord-017161-lcqrd4v0	242	18	with	with	IN
cord-017161-lcqrd4v0	242	19	the	the	DT
cord-017161-lcqrd4v0	242	20	autoantigen	autoantigen	NNP
cord-017161-lcqrd4v0	242	21	PR3	PR3	NNP
cord-017161-lcqrd4v0	242	22	results	result	VBZ
cord-017161-lcqrd4v0	242	23	in	in	IN
cord-017161-lcqrd4v0	242	24	production	production	NN
cord-017161-lcqrd4v0	242	25	of	of	IN
cord-017161-lcqrd4v0	242	26	interleukin	interleukin	NN
cord-017161-lcqrd4v0	242	27	(	(	-LRB-
cord-017161-lcqrd4v0	242	28	IL)-17	il)-17	NN
cord-017161-lcqrd4v0	242	29	and	and	CC
cord-017161-lcqrd4v0	242	30	not	not	RB
cord-017161-lcqrd4v0	242	31	INF	INF	NNP
cord-017161-lcqrd4v0	242	32	-	-	HYPH
cord-017161-lcqrd4v0	242	33	g	g	NNP
cord-017161-lcqrd4v0	242	34	,	,	,
cord-017161-lcqrd4v0	242	35	demonstrating	demonstrate	VBG
cord-017161-lcqrd4v0	242	36	that	that	IN
cord-017161-lcqrd4v0	242	37	the	the	DT
cord-017161-lcqrd4v0	242	38	autoimmune	autoimmune	JJ
cord-017161-lcqrd4v0	242	39	effector	effector	NN
cord-017161-lcqrd4v0	242	40	cells	cell	NNS
cord-017161-lcqrd4v0	242	41	are	be	VBP
cord-017161-lcqrd4v0	242	42	Th17	th17	NN
cord-017161-lcqrd4v0	242	43	cells	cell	NNS
cord-017161-lcqrd4v0	242	44	[	[	-LRB-
cord-017161-lcqrd4v0	242	45	132	132	CD
cord-017161-lcqrd4v0	242	46	]	]	-RRB-
cord-017161-lcqrd4v0	242	47	.	.	.
cord-017161-lcqrd4v0	243	1	In	in	IN
cord-017161-lcqrd4v0	243	2	healthy	healthy	JJ
cord-017161-lcqrd4v0	243	3	individuals	individual	NNS
cord-017161-lcqrd4v0	243	4	regulatory	regulatory	JJ
cord-017161-lcqrd4v0	243	5	T	t	NN
cord-017161-lcqrd4v0	243	6	cells	cell	NNS
cord-017161-lcqrd4v0	243	7	(	(	-LRB-
cord-017161-lcqrd4v0	243	8	Tregs	Tregs	NNP
cord-017161-lcqrd4v0	243	9	)	)	-RRB-
cord-017161-lcqrd4v0	243	10	control	control	VB
cord-017161-lcqrd4v0	243	11	the	the	DT
cord-017161-lcqrd4v0	243	12	activity	activity	NN
cord-017161-lcqrd4v0	243	13	of	of	IN
cord-017161-lcqrd4v0	243	14	immune	immune	JJ
cord-017161-lcqrd4v0	243	15	effector	effector	NN
cord-017161-lcqrd4v0	243	16	cells	cell	NNS
cord-017161-lcqrd4v0	243	17	[	[	-LRB-
cord-017161-lcqrd4v0	243	18	131	131	CD
cord-017161-lcqrd4v0	243	19	]	]	-RRB-
cord-017161-lcqrd4v0	243	20	.	.	.
cord-017161-lcqrd4v0	244	1	There	there	EX
cord-017161-lcqrd4v0	244	2	is	be	VBZ
cord-017161-lcqrd4v0	244	3	increasing	increase	VBG
cord-017161-lcqrd4v0	244	4	evidence	evidence	NN
cord-017161-lcqrd4v0	244	5	that	that	IN
cord-017161-lcqrd4v0	244	6	the	the	DT
cord-017161-lcqrd4v0	244	7	balance	balance	NN
cord-017161-lcqrd4v0	244	8	between	between	IN
cord-017161-lcqrd4v0	244	9	Th17	Th17	NNP
cord-017161-lcqrd4v0	244	10	cells	cell	NNS
cord-017161-lcqrd4v0	244	11	and	and	CC
cord-017161-lcqrd4v0	244	12	Fox	Fox	NNP
cord-017161-lcqrd4v0	244	13	P3-positive	P3-positive	NNP
cord-017161-lcqrd4v0	244	14	regulatory	regulatory	JJ
cord-017161-lcqrd4v0	244	15	T	t	NN
cord-017161-lcqrd4v0	244	16	cells	cell	NNS
cord-017161-lcqrd4v0	244	17	is	be	VBZ
cord-017161-lcqrd4v0	244	18	disturbed	disturb	VBN
cord-017161-lcqrd4v0	244	19	in	in	IN
cord-017161-lcqrd4v0	244	20	autoimmune	autoimmune	NN
cord-017161-lcqrd4v0	244	21	in	in	IN
cord-017161-lcqrd4v0	244	22	fl	fl	NNP
cord-017161-lcqrd4v0	244	23	ammatory	ammatory	NNP
cord-017161-lcqrd4v0	244	24	conditions	condition	NNS
cord-017161-lcqrd4v0	244	25	[	[	-LRB-
cord-017161-lcqrd4v0	244	26	131	131	CD
cord-017161-lcqrd4v0	244	27	]	]	-RRB-
cord-017161-lcqrd4v0	244	28	.	.	.
cord-017161-lcqrd4v0	245	1	In	in	IN
cord-017161-lcqrd4v0	245	2	patients	patient	NNS
cord-017161-lcqrd4v0	245	3	with	with	IN
cord-017161-lcqrd4v0	245	4	WG	WG	NNP
cord-017161-lcqrd4v0	245	5	in	in	IN
cord-017161-lcqrd4v0	245	6	remission	remission	NN
cord-017161-lcqrd4v0	245	7	,	,	,
cord-017161-lcqrd4v0	245	8	the	the	DT
cord-017161-lcqrd4v0	245	9	percentage	percentage	NN
cord-017161-lcqrd4v0	245	10	of	of	IN
cord-017161-lcqrd4v0	245	11	Fox	Fox	NNP
cord-017161-lcqrd4v0	245	12	P3-positive	P3-positive	NNP
cord-017161-lcqrd4v0	245	13	Tregs	Tregs	NNP
cord-017161-lcqrd4v0	245	14	was	be	VBD
cord-017161-lcqrd4v0	245	15	shown	show	VBN
cord-017161-lcqrd4v0	245	16	to	to	TO
cord-017161-lcqrd4v0	245	17	be	be	VB
cord-017161-lcqrd4v0	245	18	increased	increase	VBN
cord-017161-lcqrd4v0	245	19	but	but	CC
cord-017161-lcqrd4v0	245	20	the	the	DT
cord-017161-lcqrd4v0	245	21	cells	cell	NNS
cord-017161-lcqrd4v0	245	22	were	be	VBD
cord-017161-lcqrd4v0	245	23	functionally	functionally	RB
cord-017161-lcqrd4v0	245	24	de	de	FW
cord-017161-lcqrd4v0	245	25	fi	fi	NN
cord-017161-lcqrd4v0	245	26	cient	cient	NN
cord-017161-lcqrd4v0	245	27	[	[	-LRB-
cord-017161-lcqrd4v0	245	28	133	133	CD
cord-017161-lcqrd4v0	245	29	]	]	-RRB-
cord-017161-lcqrd4v0	245	30	.	.	.
cord-017161-lcqrd4v0	246	1	Taken	take	VBN
cord-017161-lcqrd4v0	246	2	together	together	RB
cord-017161-lcqrd4v0	246	3	,	,	,
cord-017161-lcqrd4v0	246	4	in	in	IN
cord-017161-lcqrd4v0	246	5	vitro	vitro	FW
cord-017161-lcqrd4v0	246	6	studies	study	NNS
cord-017161-lcqrd4v0	246	7	support	support	VBP
cord-017161-lcqrd4v0	246	8	a	a	DT
cord-017161-lcqrd4v0	246	9	pathogenic	pathogenic	JJ
cord-017161-lcqrd4v0	246	10	role	role	NN
cord-017161-lcqrd4v0	246	11	for	for	IN
cord-017161-lcqrd4v0	246	12	the	the	DT
cord-017161-lcqrd4v0	246	13	autoimmune	autoimmune	JJ
cord-017161-lcqrd4v0	246	14	responses	response	NNS
cord-017161-lcqrd4v0	246	15	to	to	IN
cord-017161-lcqrd4v0	246	16	PR3	PR3	NNP
cord-017161-lcqrd4v0	246	17	and	and	CC
cord-017161-lcqrd4v0	246	18	MPO	MPO	NNP
cord-017161-lcqrd4v0	246	19	in	in	IN
cord-017161-lcqrd4v0	246	20	AAV	AAV	NNP
cord-017161-lcqrd4v0	246	21	.	.	.
cord-017161-lcqrd4v0	247	1	Autoantibodies	Autoantibodies	NNP
cord-017161-lcqrd4v0	247	2	could	could	MD
cord-017161-lcqrd4v0	247	3	be	be	VB
cord-017161-lcqrd4v0	247	4	responsible	responsible	JJ
cord-017161-lcqrd4v0	247	5	for	for	IN
cord-017161-lcqrd4v0	247	6	smallvessel	smallvessel	NN
cord-017161-lcqrd4v0	247	7	necrotizing	necrotize	VBG
cord-017161-lcqrd4v0	247	8	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	247	9	,	,	,
cord-017161-lcqrd4v0	247	10	whereas	whereas	IN
cord-017161-lcqrd4v0	247	11	dysregulation	dysregulation	NN
cord-017161-lcqrd4v0	247	12	of	of	IN
cord-017161-lcqrd4v0	247	13	T	t	NN
cord-017161-lcqrd4v0	247	14	-	-	HYPH
cord-017161-lcqrd4v0	247	15	cell	cell	NN
cord-017161-lcqrd4v0	247	16	homoeostasis	homoeostasis	NN
cord-017161-lcqrd4v0	247	17	may	may	MD
cord-017161-lcqrd4v0	247	18	underlie	underlie	VB
cord-017161-lcqrd4v0	247	19	granulomatous	granulomatous	JJ
cord-017161-lcqrd4v0	247	20	in	in	IN
cord-017161-lcqrd4v0	247	21	fl	fl	NNP
cord-017161-lcqrd4v0	247	22	ammation	ammation	NNP
cord-017161-lcqrd4v0	247	23	.	.	.
cord-017161-lcqrd4v0	248	1	Evidence	evidence	NN
cord-017161-lcqrd4v0	248	2	for	for	IN
cord-017161-lcqrd4v0	248	3	a	a	DT
cord-017161-lcqrd4v0	248	4	pathogenic	pathogenic	JJ
cord-017161-lcqrd4v0	248	5	role	role	NN
cord-017161-lcqrd4v0	248	6	of	of	IN
cord-017161-lcqrd4v0	248	7	MPO	MPO	NNP
cord-017161-lcqrd4v0	248	8	-	-	HYPH
cord-017161-lcqrd4v0	248	9	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	248	10	in	in	IN
cord-017161-lcqrd4v0	248	11	AAV	AAV	NNP
cord-017161-lcqrd4v0	248	12	comes	come	VBZ
cord-017161-lcqrd4v0	248	13	from	from	IN
cord-017161-lcqrd4v0	248	14	animal	animal	NN
cord-017161-lcqrd4v0	248	15	models	model	NNS
cord-017161-lcqrd4v0	248	16	for	for	IN
cord-017161-lcqrd4v0	248	17	MPO	MPO	NNP
cord-017161-lcqrd4v0	248	18	-	-	HYPH
cord-017161-lcqrd4v0	248	19	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	248	20	-	-	HYPH
cord-017161-lcqrd4v0	248	21	associated	associate	VBN
cord-017161-lcqrd4v0	248	22	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	248	23	[	[	-LRB-
cord-017161-lcqrd4v0	248	24	134	134	CD
cord-017161-lcqrd4v0	248	25	]	]	-RRB-
cord-017161-lcqrd4v0	248	26	.	.	.
cord-017161-lcqrd4v0	249	1	Xiao	Xiao	NNP
cord-017161-lcqrd4v0	249	2	et	et	NNP
cord-017161-lcqrd4v0	249	3	al	al	NNP
cord-017161-lcqrd4v0	249	4	.	.	.
cord-017161-lcqrd4v0	250	1	immunized	immunize	VBN
cord-017161-lcqrd4v0	250	2	mice	mouse	NNS
cord-017161-lcqrd4v0	250	3	de	de	NNP
cord-017161-lcqrd4v0	250	4	fi	fi	NN
cord-017161-lcqrd4v0	250	5	cient	cient	NN
cord-017161-lcqrd4v0	250	6	for	for	IN
cord-017161-lcqrd4v0	250	7	MPO	MPO	NNP
cord-017161-lcqrd4v0	250	8	with	with	IN
cord-017161-lcqrd4v0	250	9	mouse	mouse	NN
cord-017161-lcqrd4v0	250	10	MPO	MPO	NNP
cord-017161-lcqrd4v0	250	11	and	and	CC
cord-017161-lcqrd4v0	250	12	transferred	transfer	VBD
cord-017161-lcqrd4v0	250	13	splenocytes	splenocytes	NNP
cord-017161-lcqrd4v0	250	14	from	from	IN
cord-017161-lcqrd4v0	250	15	these	these	DT
cord-017161-lcqrd4v0	250	16	immunized	immunize	VBN
cord-017161-lcqrd4v0	250	17	mice	mouse	NNS
cord-017161-lcqrd4v0	250	18	into	into	IN
cord-017161-lcqrd4v0	250	19	immunode	immunode	NNP
cord-017161-lcqrd4v0	250	20	fi	fi	NNP
cord-017161-lcqrd4v0	250	21	cient	cient	NNP
cord-017161-lcqrd4v0	250	22	or	or	CC
cord-017161-lcqrd4v0	250	23	normal	normal	JJ
cord-017161-lcqrd4v0	250	24	mice	mouse	NNS
cord-017161-lcqrd4v0	250	25	[	[	-LRB-
cord-017161-lcqrd4v0	250	26	134	134	CD
cord-017161-lcqrd4v0	250	27	]	]	-RRB-
cord-017161-lcqrd4v0	250	28	.	.	.
cord-017161-lcqrd4v0	251	1	The	the	DT
cord-017161-lcqrd4v0	251	2	recipient	recipient	NN
cord-017161-lcqrd4v0	251	3	mice	mouse	NNS
cord-017161-lcqrd4v0	251	4	developed	develop	VBD
cord-017161-lcqrd4v0	251	5	pauci	pauci	NN
cord-017161-lcqrd4v0	251	6	-	-	HYPH
cord-017161-lcqrd4v0	251	7	immune	immune	JJ
cord-017161-lcqrd4v0	251	8	necrotizing	necrotize	VBG
cord-017161-lcqrd4v0	251	9	glomerulonephritis	glomerulonephritis	NN
cord-017161-lcqrd4v0	251	10	and	and	CC
cord-017161-lcqrd4v0	251	11	haemorrhagic	haemorrhagic	JJ
cord-017161-lcqrd4v0	251	12	pulmonary	pulmonary	JJ
cord-017161-lcqrd4v0	251	13	capillaritis	capillaritis	NN
cord-017161-lcqrd4v0	251	14	,	,	,
cord-017161-lcqrd4v0	251	15	similar	similar	JJ
cord-017161-lcqrd4v0	251	16	to	to	IN
cord-017161-lcqrd4v0	251	17	the	the	DT
cord-017161-lcqrd4v0	251	18	clinical	clinical	JJ
cord-017161-lcqrd4v0	251	19	manifestations	manifestation	NNS
cord-017161-lcqrd4v0	251	20	and	and	CC
cord-017161-lcqrd4v0	251	21	the	the	DT
cord-017161-lcqrd4v0	251	22	histopathology	histopathology	NN
cord-017161-lcqrd4v0	251	23	of	of	IN
cord-017161-lcqrd4v0	251	24	MPO	MPO	NNP
cord-017161-lcqrd4v0	251	25	-	-	HYPH
cord-017161-lcqrd4v0	251	26	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	251	27	-	-	HYPH
cord-017161-lcqrd4v0	251	28	associated	associate	VBN
cord-017161-lcqrd4v0	251	29	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	251	30	[	[	-LRB-
cord-017161-lcqrd4v0	251	31	134	134	CD
cord-017161-lcqrd4v0	251	32	]	]	-RRB-
cord-017161-lcqrd4v0	251	33	.	.	.
cord-017161-lcqrd4v0	252	1	In	in	IN
cord-017161-lcqrd4v0	252	2	addition	addition	NN
cord-017161-lcqrd4v0	252	3	,	,	,
cord-017161-lcqrd4v0	252	4	transfer	transfer	NN
cord-017161-lcqrd4v0	252	5	of	of	IN
cord-017161-lcqrd4v0	252	6	IgG	igg	NN
cord-017161-lcqrd4v0	252	7	alone	alone	RB
cord-017161-lcqrd4v0	252	8	from	from	IN
cord-017161-lcqrd4v0	252	9	MPO	MPO	NNP
cord-017161-lcqrd4v0	252	10	-	-	HYPH
cord-017161-lcqrd4v0	252	11	immunized	immunize	VBN
cord-017161-lcqrd4v0	252	12	mice	mouse	NNS
cord-017161-lcqrd4v0	252	13	resulted	result	VBD
cord-017161-lcqrd4v0	252	14	in	in	IN
cord-017161-lcqrd4v0	252	15	pauci	pauci	NN
cord-017161-lcqrd4v0	252	16	-	-	HYPH
cord-017161-lcqrd4v0	252	17	immune	immune	JJ
cord-017161-lcqrd4v0	252	18	focal	focal	JJ
cord-017161-lcqrd4v0	252	19	necrotizing	necrotize	VBG
cord-017161-lcqrd4v0	252	20	glomerulonephritis	glomerulonephritis	NN
cord-017161-lcqrd4v0	252	21	in	in	IN
cord-017161-lcqrd4v0	252	22	the	the	DT
cord-017161-lcqrd4v0	252	23	recipient	recipient	NN
cord-017161-lcqrd4v0	252	24	,	,	,
cord-017161-lcqrd4v0	252	25	demonstrating	demonstrate	VBG
cord-017161-lcqrd4v0	252	26	the	the	DT
cord-017161-lcqrd4v0	252	27	pathogenic	pathogenic	JJ
cord-017161-lcqrd4v0	252	28	potential	potential	NN
cord-017161-lcqrd4v0	252	29	of	of	IN
cord-017161-lcqrd4v0	252	30	anti	anti	JJ
cord-017161-lcqrd4v0	252	31	-	-	JJ
cord-017161-lcqrd4v0	252	32	MPO	MPO	NNP
cord-017161-lcqrd4v0	252	33	antibodies	antibody	NNS
cord-017161-lcqrd4v0	252	34	[	[	-LRB-
cord-017161-lcqrd4v0	252	35	134	134	CD
cord-017161-lcqrd4v0	252	36	]	]	-RRB-
cord-017161-lcqrd4v0	252	37	.	.	.
cord-017161-lcqrd4v0	253	1	Additional	additional	JJ
cord-017161-lcqrd4v0	253	2	studies	study	NNS
cord-017161-lcqrd4v0	253	3	showed	show	VBD
cord-017161-lcqrd4v0	253	4	that	that	IN
cord-017161-lcqrd4v0	253	5	both	both	DT
cord-017161-lcqrd4v0	253	6	neutrophils	neutrophil	NNS
cord-017161-lcqrd4v0	253	7	expressing	express	VBG
cord-017161-lcqrd4v0	253	8	MPO	MPO	NNP
cord-017161-lcqrd4v0	253	9	and	and	CC
cord-017161-lcqrd4v0	253	10	the	the	DT
cord-017161-lcqrd4v0	253	11	alternative	alternative	JJ
cord-017161-lcqrd4v0	253	12	pathway	pathway	NN
cord-017161-lcqrd4v0	253	13	of	of	IN
cord-017161-lcqrd4v0	253	14	complement	complement	NN
cord-017161-lcqrd4v0	253	15	besides	besides	IN
cord-017161-lcqrd4v0	253	16	the	the	DT
cord-017161-lcqrd4v0	253	17	antibodies	antibody	NNS
cord-017161-lcqrd4v0	253	18	are	be	VBP
cord-017161-lcqrd4v0	253	19	required	require	VBN
cord-017161-lcqrd4v0	253	20	to	to	TO
cord-017161-lcqrd4v0	253	21	induce	induce	VB
cord-017161-lcqrd4v0	253	22	AAV	AAV	NNP
cord-017161-lcqrd4v0	253	23	as	as	IN
cord-017161-lcqrd4v0	253	24	recipient	recipient	NN
cord-017161-lcqrd4v0	253	25	mice	mouse	NNS
cord-017161-lcqrd4v0	253	26	de	de	NNP
cord-017161-lcqrd4v0	253	27	fi	fi	NNP
cord-017161-lcqrd4v0	253	28	cient	cient	NN
cord-017161-lcqrd4v0	253	29	for	for	IN
cord-017161-lcqrd4v0	253	30	factor	factor	NN
cord-017161-lcqrd4v0	253	31	B	b	NN
cord-017161-lcqrd4v0	253	32	and	and	CC
cord-017161-lcqrd4v0	253	33	complement	complement	VB
cord-017161-lcqrd4v0	253	34	C5	C5	NNP
cord-017161-lcqrd4v0	253	35	did	do	VBD
cord-017161-lcqrd4v0	253	36	not	not	RB
cord-017161-lcqrd4v0	253	37	develop	develop	VB
cord-017161-lcqrd4v0	253	38	disease	disease	NN
cord-017161-lcqrd4v0	253	39	[	[	-LRB-
cord-017161-lcqrd4v0	253	40	135	135	CD
cord-017161-lcqrd4v0	253	41	]	]	-RRB-
cord-017161-lcqrd4v0	253	42	.	.	.
cord-017161-lcqrd4v0	254	1	Also	also	RB
cord-017161-lcqrd4v0	254	2	in	in	IN
cord-017161-lcqrd4v0	254	3	a	a	DT
cord-017161-lcqrd4v0	254	4	rat	rat	NN
cord-017161-lcqrd4v0	254	5	model	model	NN
cord-017161-lcqrd4v0	254	6	of	of	IN
cord-017161-lcqrd4v0	254	7	MPO	MPO	NNP
cord-017161-lcqrd4v0	254	8	-	-	HYPH
cord-017161-lcqrd4v0	254	9	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	254	10	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	254	11	,	,	,
cord-017161-lcqrd4v0	254	12	in	in	IN
cord-017161-lcqrd4v0	254	13	which	which	WDT
cord-017161-lcqrd4v0	254	14	rats	rat	NNS
cord-017161-lcqrd4v0	254	15	were	be	VBD
cord-017161-lcqrd4v0	254	16	immunized	immunize	VBN
cord-017161-lcqrd4v0	254	17	with	with	IN
cord-017161-lcqrd4v0	254	18	human	human	JJ
cord-017161-lcqrd4v0	254	19	MPO	MPO	NNP
cord-017161-lcqrd4v0	254	20	,	,	,
cord-017161-lcqrd4v0	254	21	the	the	DT
cord-017161-lcqrd4v0	254	22	pathogenic	pathogenic	JJ
cord-017161-lcqrd4v0	254	23	potential	potential	NN
cord-017161-lcqrd4v0	254	24	of	of	IN
cord-017161-lcqrd4v0	254	25	anti	anti	JJ
cord-017161-lcqrd4v0	254	26	-	-	JJ
cord-017161-lcqrd4v0	254	27	MPO	MPO	NNP
cord-017161-lcqrd4v0	254	28	antibodies	antibody	NNS
cord-017161-lcqrd4v0	254	29	was	be	VBD
cord-017161-lcqrd4v0	254	30	demonstrated	demonstrate	VBN
cord-017161-lcqrd4v0	254	31	[	[	-LRB-
cord-017161-lcqrd4v0	254	32	136	136	CD
cord-017161-lcqrd4v0	254	33	]	]	-RRB-
cord-017161-lcqrd4v0	254	34	.	.	.
cord-017161-lcqrd4v0	255	1	Of	of	IN
cord-017161-lcqrd4v0	255	2	note	note	NN
cord-017161-lcqrd4v0	255	3	,	,	,
cord-017161-lcqrd4v0	255	4	however	however	RB
cord-017161-lcqrd4v0	255	5	,	,	,
cord-017161-lcqrd4v0	255	6	no	no	DT
cord-017161-lcqrd4v0	255	7	animal	animal	NN
cord-017161-lcqrd4v0	255	8	models	model	NNS
cord-017161-lcqrd4v0	255	9	for	for	IN
cord-017161-lcqrd4v0	255	10	PR3-ANCA	PR3-ANCA	NNP
cord-017161-lcqrd4v0	255	11	-	-	HYPH
cord-017161-lcqrd4v0	255	12	associated	associate	VBN
cord-017161-lcqrd4v0	255	13	WG	WG	NNP
cord-017161-lcqrd4v0	255	14	have	have	VBP
cord-017161-lcqrd4v0	255	15	been	be	VBN
cord-017161-lcqrd4v0	255	16	generated	generate	VBN
cord-017161-lcqrd4v0	255	17	[	[	-LRB-
cord-017161-lcqrd4v0	255	18	110	110	CD
cord-017161-lcqrd4v0	255	19	]	]	-RRB-
cord-017161-lcqrd4v0	255	20	.	.	.
cord-017161-lcqrd4v0	256	1	A	a	DT
cord-017161-lcqrd4v0	256	2	series	series	NN
cord-017161-lcqrd4v0	256	3	of	of	IN
cord-017161-lcqrd4v0	256	4	early	early	JJ
cord-017161-lcqrd4v0	256	5	observations	observation	NNS
cord-017161-lcqrd4v0	256	6	have	have	VBP
cord-017161-lcqrd4v0	256	7	suggested	suggest	VBN
cord-017161-lcqrd4v0	256	8	that	that	IN
cord-017161-lcqrd4v0	256	9	infectious	infectious	JJ
cord-017161-lcqrd4v0	256	10	episodes	episode	NNS
cord-017161-lcqrd4v0	256	11	may	may	MD
cord-017161-lcqrd4v0	256	12	trigger	trigger	VB
cord-017161-lcqrd4v0	256	13	relapses	relapse	NNS
cord-017161-lcqrd4v0	256	14	of	of	IN
cord-017161-lcqrd4v0	256	15	AAV	AAV	NNP
cord-017161-lcqrd4v0	256	16	[	[	-LRB-
cord-017161-lcqrd4v0	256	17	137	137	CD
cord-017161-lcqrd4v0	256	18	]	]	-RRB-
cord-017161-lcqrd4v0	256	19	.	.	.
cord-017161-lcqrd4v0	257	1	Further	further	JJ
cord-017161-lcqrd4v0	257	2	studies	study	NNS
cord-017161-lcqrd4v0	257	3	of	of	IN
cord-017161-lcqrd4v0	257	4	upper	upper	JJ
cord-017161-lcqrd4v0	257	5	airway	airway	NN
cord-017161-lcqrd4v0	257	6	involvement	involvement	NN
cord-017161-lcqrd4v0	257	7	in	in	IN
cord-017161-lcqrd4v0	257	8	WG	WG	NNP
cord-017161-lcqrd4v0	257	9	showed	show	VBD
cord-017161-lcqrd4v0	257	10	good	good	JJ
cord-017161-lcqrd4v0	257	11	responses	response	NNS
cord-017161-lcqrd4v0	257	12	to	to	IN
cord-017161-lcqrd4v0	257	13	treatment	treatment	NN
cord-017161-lcqrd4v0	257	14	with	with	IN
cord-017161-lcqrd4v0	257	15	trimethoprim	trimethoprim	NNP
cord-017161-lcqrd4v0	257	16	/	/	SYM
cord-017161-lcqrd4v0	257	17	sulphamethoxazole	sulphamethoxazole	NNP
cord-017161-lcqrd4v0	257	18	[	[	-LRB-
cord-017161-lcqrd4v0	257	19	138	138	CD
cord-017161-lcqrd4v0	257	20	]	]	-RRB-
cord-017161-lcqrd4v0	257	21	.	.	.
cord-017161-lcqrd4v0	258	1	Longterm	longterm	JJ
cord-017161-lcqrd4v0	258	2	studies	study	NNS
cord-017161-lcqrd4v0	258	3	demonstrated	demonstrate	VBD
cord-017161-lcqrd4v0	258	4	that	that	IN
cord-017161-lcqrd4v0	258	5	chronic	chronic	JJ
cord-017161-lcqrd4v0	258	6	nasal	nasal	NN
cord-017161-lcqrd4v0	258	7	carriage	carriage	NN
cord-017161-lcqrd4v0	258	8	of	of	IN
cord-017161-lcqrd4v0	258	9	Staphylococcus	Staphylococcus	NNP
cord-017161-lcqrd4v0	258	10	aureus	aureus	NN
cord-017161-lcqrd4v0	258	11	is	be	VBZ
cord-017161-lcqrd4v0	258	12	a	a	DT
cord-017161-lcqrd4v0	258	13	major	major	JJ
cord-017161-lcqrd4v0	258	14	risk	risk	NN
cord-017161-lcqrd4v0	258	15	factor	factor	NN
cord-017161-lcqrd4v0	258	16	for	for	IN
cord-017161-lcqrd4v0	258	17	relapse	relapse	NN
cord-017161-lcqrd4v0	258	18	in	in	IN
cord-017161-lcqrd4v0	258	19	WG	WG	NNP
cord-017161-lcqrd4v0	258	20	in	in	IN
cord-017161-lcqrd4v0	258	21	conjunction	conjunction	NN
cord-017161-lcqrd4v0	258	22	with	with	IN
cord-017161-lcqrd4v0	258	23	persistence	persistence	NN
cord-017161-lcqrd4v0	258	24	of	of	IN
cord-017161-lcqrd4v0	258	25	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	258	26	,	,	,
cord-017161-lcqrd4v0	258	27	and	and	CC
cord-017161-lcqrd4v0	258	28	maintenance	maintenance	NN
cord-017161-lcqrd4v0	258	29	treatment	treatment	NN
cord-017161-lcqrd4v0	258	30	with	with	IN
cord-017161-lcqrd4v0	258	31	trimethoprim	trimethoprim	NNP
cord-017161-lcqrd4v0	258	32	/	/	SYM
cord-017161-lcqrd4v0	258	33	sulphamethoxazole	sulphamethoxazole	NNP
cord-017161-lcqrd4v0	258	34	reduced	reduce	VBD
cord-017161-lcqrd4v0	258	35	the	the	DT
cord-017161-lcqrd4v0	258	36	occurrence	occurrence	NN
cord-017161-lcqrd4v0	258	37	of	of	IN
cord-017161-lcqrd4v0	258	38	relapses	relapse	NNS
cord-017161-lcqrd4v0	258	39	by	by	IN
cord-017161-lcqrd4v0	258	40	60	60	CD
cord-017161-lcqrd4v0	258	41	%	%	NN
cord-017161-lcqrd4v0	258	42	in	in	IN
cord-017161-lcqrd4v0	258	43	patients	patient	NNS
cord-017161-lcqrd4v0	258	44	with	with	IN
cord-017161-lcqrd4v0	258	45	WG	WG	NNP
cord-017161-lcqrd4v0	258	46	[	[	-LRB-
cord-017161-lcqrd4v0	258	47	139	139	CD
cord-017161-lcqrd4v0	258	48	]	]	-RRB-
cord-017161-lcqrd4v0	258	49	.	.	.
cord-017161-lcqrd4v0	259	1	Possible	possible	JJ
cord-017161-lcqrd4v0	259	2	mechanisms	mechanism	NNS
cord-017161-lcqrd4v0	259	3	whereby	whereby	WRB
cord-017161-lcqrd4v0	259	4	S.	S.	NNP
cord-017161-lcqrd4v0	259	5	aureus	aureus	NN
cord-017161-lcqrd4v0	259	6	could	could	MD
cord-017161-lcqrd4v0	259	7	result	result	VB
cord-017161-lcqrd4v0	259	8	in	in	IN
cord-017161-lcqrd4v0	259	9	fl	fl	NNP
cord-017161-lcqrd4v0	259	10	ares	ares	NNP
cord-017161-lcqrd4v0	259	11	of	of	IN
cord-017161-lcqrd4v0	259	12	WG	WG	NNP
cord-017161-lcqrd4v0	259	13	include	include	VBP
cord-017161-lcqrd4v0	259	14	SAg	SAg	NNS
cord-017161-lcqrd4v0	259	15	production	production	NN
cord-017161-lcqrd4v0	259	16	and	and	CC
cord-017161-lcqrd4v0	259	17	T	t	NN
cord-017161-lcqrd4v0	259	18	-	-	HYPH
cord-017161-lcqrd4v0	259	19	and	and	CC
cord-017161-lcqrd4v0	259	20	B	b	NN
cord-017161-lcqrd4v0	259	21	-	-	HYPH
cord-017161-lcqrd4v0	259	22	cell	cell	NN
cord-017161-lcqrd4v0	259	23	activation	activation	NN
cord-017161-lcqrd4v0	259	24	,	,	,
cord-017161-lcqrd4v0	259	25	direct	direct	JJ
cord-017161-lcqrd4v0	259	26	tropism	tropism	NN
cord-017161-lcqrd4v0	259	27	of	of	IN
cord-017161-lcqrd4v0	259	28	S.	S.	NNP
cord-017161-lcqrd4v0	259	29	aureus	aureus	NN
cord-017161-lcqrd4v0	259	30	for	for	IN
cord-017161-lcqrd4v0	259	31	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	259	32	cells	cell	NNS
cord-017161-lcqrd4v0	259	33	,	,	,
cord-017161-lcqrd4v0	259	34	with	with	IN
cord-017161-lcqrd4v0	259	35	binding	binding	NN
cord-017161-lcqrd4v0	259	36	and	and	CC
cord-017161-lcqrd4v0	259	37	internalization	internalization	NN
cord-017161-lcqrd4v0	259	38	of	of	IN
cord-017161-lcqrd4v0	259	39	the	the	DT
cord-017161-lcqrd4v0	259	40	organism	organism	NN
cord-017161-lcqrd4v0	259	41	by	by	IN
cord-017161-lcqrd4v0	259	42	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	259	43	cells	cell	NNS
cord-017161-lcqrd4v0	259	44	or	or	CC
cord-017161-lcqrd4v0	259	45	by	by	IN
cord-017161-lcqrd4v0	259	46	priming	prime	VBG
cord-017161-lcqrd4v0	259	47	of	of	IN
cord-017161-lcqrd4v0	259	48	neutrophils	neutrophil	NNS
cord-017161-lcqrd4v0	259	49	[	[	-LRB-
cord-017161-lcqrd4v0	259	50	140	140	CD
cord-017161-lcqrd4v0	259	51	]	]	-RRB-
cord-017161-lcqrd4v0	259	52	.	.	.
cord-017161-lcqrd4v0	260	1	Recently	recently	RB
cord-017161-lcqrd4v0	260	2	,	,	,
cord-017161-lcqrd4v0	260	3	two	two	CD
cord-017161-lcqrd4v0	260	4	studies	study	NNS
cord-017161-lcqrd4v0	260	5	have	have	VBP
cord-017161-lcqrd4v0	260	6	shed	shed	VBN
cord-017161-lcqrd4v0	260	7	new	new	JJ
cord-017161-lcqrd4v0	260	8	light	light	NN
cord-017161-lcqrd4v0	260	9	on	on	IN
cord-017161-lcqrd4v0	260	10	the	the	DT
cord-017161-lcqrd4v0	260	11	possible	possible	JJ
cord-017161-lcqrd4v0	260	12	role	role	NN
cord-017161-lcqrd4v0	260	13	of	of	IN
cord-017161-lcqrd4v0	260	14	microbial	microbial	JJ
cord-017161-lcqrd4v0	260	15	factors	factor	NNS
cord-017161-lcqrd4v0	260	16	in	in	IN
cord-017161-lcqrd4v0	260	17	the	the	DT
cord-017161-lcqrd4v0	260	18	pathogenesis	pathogenesis	NN
cord-017161-lcqrd4v0	260	19	of	of	IN
cord-017161-lcqrd4v0	260	20	AAV	AAV	NNP
cord-017161-lcqrd4v0	260	21	.	.	.
cord-017161-lcqrd4v0	261	1	In	in	IN
cord-017161-lcqrd4v0	261	2	the	the	DT
cord-017161-lcqrd4v0	261	3	fi	fi	NNP
cord-017161-lcqrd4v0	261	4	rst	rst	NN
cord-017161-lcqrd4v0	261	5	study	study	NN
cord-017161-lcqrd4v0	261	6	,	,	,
cord-017161-lcqrd4v0	261	7	antibodies	antibody	NNS
cord-017161-lcqrd4v0	261	8	to	to	IN
cord-017161-lcqrd4v0	261	9	complementary	complementary	JJ
cord-017161-lcqrd4v0	261	10	PR3	PR3	NNP
cord-017161-lcqrd4v0	261	11	were	be	VBD
cord-017161-lcqrd4v0	261	12	detected	detect	VBN
cord-017161-lcqrd4v0	261	13	in	in	IN
cord-017161-lcqrd4v0	261	14	serum	serum	NN
cord-017161-lcqrd4v0	261	15	samples	sample	NNS
cord-017161-lcqrd4v0	261	16	from	from	IN
cord-017161-lcqrd4v0	261	17	patients	patient	NNS
cord-017161-lcqrd4v0	261	18	with	with	IN
cord-017161-lcqrd4v0	261	19	PR3-ANCA	PR3-ANCA	NNP
cord-017161-lcqrd4v0	261	20	-	-	HYPH
cord-017161-lcqrd4v0	261	21	associated	associate	VBN
cord-017161-lcqrd4v0	261	22	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	261	23	[	[	-LRB-
cord-017161-lcqrd4v0	261	24	141	141	CD
cord-017161-lcqrd4v0	261	25	]	]	-RRB-
cord-017161-lcqrd4v0	261	26	.	.	.
cord-017161-lcqrd4v0	262	1	Complementary	complementary	JJ
cord-017161-lcqrd4v0	262	2	PR3	PR3	NNP
cord-017161-lcqrd4v0	262	3	is	be	VBZ
cord-017161-lcqrd4v0	262	4	a	a	DT
cord-017161-lcqrd4v0	262	5	protein	protein	NN
cord-017161-lcqrd4v0	262	6	translated	translate	VBN
cord-017161-lcqrd4v0	262	7	from	from	IN
cord-017161-lcqrd4v0	262	8	the	the	DT
cord-017161-lcqrd4v0	262	9	antisense	antisense	NN
cord-017161-lcqrd4v0	262	10	DNA	dna	NN
cord-017161-lcqrd4v0	262	11	strand	strand	NN
cord-017161-lcqrd4v0	262	12	encoding	encoding	NN
cord-017161-lcqrd4v0	262	13	PR3	pr3	NN
cord-017161-lcqrd4v0	262	14	.	.	.
cord-017161-lcqrd4v0	263	1	Such	such	PDT
cord-017161-lcqrd4v0	263	2	a	a	DT
cord-017161-lcqrd4v0	263	3	complementary	complementary	JJ
cord-017161-lcqrd4v0	263	4	protein	protein	NN
cord-017161-lcqrd4v0	263	5	is	be	VBZ
cord-017161-lcqrd4v0	263	6	a	a	DT
cord-017161-lcqrd4v0	263	7	mirror	mirror	NN
cord-017161-lcqrd4v0	263	8	of	of	IN
cord-017161-lcqrd4v0	263	9	the	the	DT
cord-017161-lcqrd4v0	263	10	original	original	JJ
cord-017161-lcqrd4v0	263	11	protein	protein	NN
cord-017161-lcqrd4v0	263	12	[	[	-LRB-
cord-017161-lcqrd4v0	263	13	141	141	CD
cord-017161-lcqrd4v0	263	14	]	]	-RRB-
cord-017161-lcqrd4v0	263	15	.	.	.
cord-017161-lcqrd4v0	264	1	As	as	IN
cord-017161-lcqrd4v0	264	2	such	such	JJ
cord-017161-lcqrd4v0	264	3	,	,	,
cord-017161-lcqrd4v0	264	4	antibodies	antibody	NNS
cord-017161-lcqrd4v0	264	5	to	to	IN
cord-017161-lcqrd4v0	264	6	a	a	DT
cord-017161-lcqrd4v0	264	7	complementary	complementary	JJ
cord-017161-lcqrd4v0	264	8	protein	protein	NN
cord-017161-lcqrd4v0	264	9	can	can	MD
cord-017161-lcqrd4v0	264	10	induce	induce	VB
cord-017161-lcqrd4v0	264	11	anti	anti	JJ
cord-017161-lcqrd4v0	264	12	-	-	JJ
cord-017161-lcqrd4v0	264	13	idiotypic	idiotypic	JJ
cord-017161-lcqrd4v0	264	14	antibodies	antibody	NNS
cord-017161-lcqrd4v0	264	15	that	that	WDT
cord-017161-lcqrd4v0	264	16	react	react	VBP
cord-017161-lcqrd4v0	264	17	with	with	IN
cord-017161-lcqrd4v0	264	18	the	the	DT
cord-017161-lcqrd4v0	264	19	original	original	JJ
cord-017161-lcqrd4v0	264	20	protein	protein	NN
cord-017161-lcqrd4v0	264	21	[	[	-LRB-
cord-017161-lcqrd4v0	264	22	141	141	CD
cord-017161-lcqrd4v0	264	23	]	]	-RRB-
cord-017161-lcqrd4v0	264	24	.	.	.
cord-017161-lcqrd4v0	265	1	Pendergraft	Pendergraft	NNP
cord-017161-lcqrd4v0	265	2	et	et	FW
cord-017161-lcqrd4v0	265	3	al	al	NNP
cord-017161-lcqrd4v0	265	4	.	.	.
cord-017161-lcqrd4v0	266	1	immunized	immunize	VBN
cord-017161-lcqrd4v0	266	2	mice	mouse	NNS
cord-017161-lcqrd4v0	266	3	with	with	IN
cord-017161-lcqrd4v0	266	4	complementary	complementary	JJ
cord-017161-lcqrd4v0	266	5	PR3	PR3	NNP
cord-017161-lcqrd4v0	266	6	,	,	,
cord-017161-lcqrd4v0	266	7	and	and	CC
cord-017161-lcqrd4v0	267	1	these	these	DT
cord-017161-lcqrd4v0	267	2	mice	mouse	NNS
cord-017161-lcqrd4v0	267	3	then	then	RB
cord-017161-lcqrd4v0	267	4	developed	develop	VBD
cord-017161-lcqrd4v0	267	5	antibodies	antibody	NNS
cord-017161-lcqrd4v0	267	6	to	to	IN
cord-017161-lcqrd4v0	267	7	PR3	PR3	NNP
cord-017161-lcqrd4v0	267	8	[	[	-LRB-
cord-017161-lcqrd4v0	267	9	141	141	CD
cord-017161-lcqrd4v0	267	10	]	]	-RRB-
cord-017161-lcqrd4v0	267	11	.	.	.
cord-017161-lcqrd4v0	268	1	This	this	DT
cord-017161-lcqrd4v0	268	2	complementary	complementary	JJ
cord-017161-lcqrd4v0	268	3	PR3	pr3	NN
cord-017161-lcqrd4v0	268	4	shows	show	VBZ
cord-017161-lcqrd4v0	268	5	homology	homology	NN
cord-017161-lcqrd4v0	268	6	with	with	IN
cord-017161-lcqrd4v0	268	7	a	a	DT
cord-017161-lcqrd4v0	268	8	number	number	NN
cord-017161-lcqrd4v0	268	9	of	of	IN
cord-017161-lcqrd4v0	268	10	microbial	microbial	JJ
cord-017161-lcqrd4v0	268	11	proteins	protein	NNS
cord-017161-lcqrd4v0	268	12	,	,	,
cord-017161-lcqrd4v0	268	13	including	include	VBG
cord-017161-lcqrd4v0	268	14	proteins	protein	NNS
cord-017161-lcqrd4v0	268	15	from	from	IN
cord-017161-lcqrd4v0	268	16	S.	S.	NNP
cord-017161-lcqrd4v0	268	17	aureus	aureus	NN
cord-017161-lcqrd4v0	268	18	[	[	-LRB-
cord-017161-lcqrd4v0	268	19	141	141	CD
cord-017161-lcqrd4v0	268	20	]	]	-RRB-
cord-017161-lcqrd4v0	268	21	.	.	.
cord-017161-lcqrd4v0	269	1	This	this	DT
cord-017161-lcqrd4v0	269	2	raises	raise	VBZ
cord-017161-lcqrd4v0	269	3	the	the	DT
cord-017161-lcqrd4v0	269	4	possibility	possibility	NN
cord-017161-lcqrd4v0	269	5	that	that	IN
cord-017161-lcqrd4v0	269	6	infection	infection	NN
cord-017161-lcqrd4v0	269	7	with	with	IN
cord-017161-lcqrd4v0	269	8	S.	S.	NNP
cord-017161-lcqrd4v0	269	9	aureus	aureus	NN
cord-017161-lcqrd4v0	269	10	could	could	MD
cord-017161-lcqrd4v0	269	11	lead	lead	VB
cord-017161-lcqrd4v0	269	12	to	to	IN
cord-017161-lcqrd4v0	269	13	antibodies	antibody	NNS
cord-017161-lcqrd4v0	269	14	cross	cross	NN
cord-017161-lcqrd4v0	269	15	-	-	JJ
cord-017161-lcqrd4v0	269	16	reacting	react	VBG
cord-017161-lcqrd4v0	269	17	with	with	IN
cord-017161-lcqrd4v0	269	18	complementary	complementary	JJ
cord-017161-lcqrd4v0	269	19	PR3	PR3	NNP
cord-017161-lcqrd4v0	269	20	,	,	,
cord-017161-lcqrd4v0	269	21	which	which	WDT
cord-017161-lcqrd4v0	269	22	,	,	,
cord-017161-lcqrd4v0	269	23	in	in	IN
cord-017161-lcqrd4v0	269	24	turn	turn	NN
cord-017161-lcqrd4v0	269	25	,	,	,
cord-017161-lcqrd4v0	269	26	evoke	evoke	VBP
cord-017161-lcqrd4v0	269	27	antibodies	antibody	NNS
cord-017161-lcqrd4v0	269	28	to	to	IN
cord-017161-lcqrd4v0	269	29	PR3	PR3	NNP
cord-017161-lcqrd4v0	269	30	by	by	IN
cord-017161-lcqrd4v0	269	31	idiotypic	idiotypic	NNP
cord-017161-lcqrd4v0	269	32	-	-	HYPH
cord-017161-lcqrd4v0	269	33	anti	anti	JJ
cord-017161-lcqrd4v0	269	34	-	-	JJ
cord-017161-lcqrd4v0	269	35	idiotypic	idiotypic	JJ
cord-017161-lcqrd4v0	269	36	interaction	interaction	NN
cord-017161-lcqrd4v0	269	37	.	.	.
cord-017161-lcqrd4v0	270	1	A	a	DT
cord-017161-lcqrd4v0	270	2	second	second	JJ
cord-017161-lcqrd4v0	270	3	study	study	NN
cord-017161-lcqrd4v0	270	4	describes	describe	VBZ
cord-017161-lcqrd4v0	270	5	antibodies	antibody	NNS
cord-017161-lcqrd4v0	270	6	to	to	IN
cord-017161-lcqrd4v0	270	7	the	the	DT
cord-017161-lcqrd4v0	270	8	lysosomal	lysosomal	JJ
cord-017161-lcqrd4v0	270	9	membrane	membrane	NN
cord-017161-lcqrd4v0	270	10	glycoprotein	glycoprotein	NN
cord-017161-lcqrd4v0	270	11	2	2	CD
cord-017161-lcqrd4v0	270	12	(	(	-LRB-
cord-017161-lcqrd4v0	270	13	hLAMP-2	hLAMP-2	NNP
cord-017161-lcqrd4v0	270	14	)	)	-RRB-
cord-017161-lcqrd4v0	270	15	as	as	IN
cord-017161-lcqrd4v0	270	16	a	a	DT
cord-017161-lcqrd4v0	270	17	sensitive	sensitive	JJ
cord-017161-lcqrd4v0	270	18	and	and	CC
cord-017161-lcqrd4v0	270	19	speci	speci	NNP
cord-017161-lcqrd4v0	270	20	fi	fi	NN
cord-017161-lcqrd4v0	270	21	c	c	NN
cord-017161-lcqrd4v0	270	22	marker	marker	NN
cord-017161-lcqrd4v0	270	23	for	for	IN
cord-017161-lcqrd4v0	270	24	pauci	pauci	NN
cord-017161-lcqrd4v0	270	25	-	-	HYPH
cord-017161-lcqrd4v0	270	26	immune	immune	JJ
cord-017161-lcqrd4v0	270	27	crescentic	crescentic	JJ
cord-017161-lcqrd4v0	270	28	glomerulonephritis	glomerulonephritis	NN
cord-017161-lcqrd4v0	270	29	[	[	-LRB-
cord-017161-lcqrd4v0	270	30	142	142	CD
cord-017161-lcqrd4v0	270	31	]	]	-RRB-
cord-017161-lcqrd4v0	270	32	.	.	.
cord-017161-lcqrd4v0	271	1	hLAMP-2	hLAMP-2	NNP
cord-017161-lcqrd4v0	271	2	is	be	VBZ
cord-017161-lcqrd4v0	271	3	present	present	JJ
cord-017161-lcqrd4v0	271	4	on	on	IN
cord-017161-lcqrd4v0	271	5	neutrophils	neutrophil	NNS
cord-017161-lcqrd4v0	271	6	and	and	CC
cord-017161-lcqrd4v0	271	7	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	271	8	cells	cell	NNS
cord-017161-lcqrd4v0	271	9	[	[	-LRB-
cord-017161-lcqrd4v0	271	10	142	142	CD
cord-017161-lcqrd4v0	271	11	]	]	-RRB-
cord-017161-lcqrd4v0	271	12	.	.	.
cord-017161-lcqrd4v0	272	1	Anti	Anti	NNP
cord-017161-lcqrd4v0	272	2	-	-	NNP
cord-017161-lcqrd4v0	272	3	hLAMP-2	hLAMP-2	NNP
cord-017161-lcqrd4v0	272	4	antibodies	antibody	NNS
cord-017161-lcqrd4v0	272	5	,	,	,
cord-017161-lcqrd4v0	272	6	raised	raise	VBN
cord-017161-lcqrd4v0	272	7	in	in	IN
cord-017161-lcqrd4v0	272	8	rabbits	rabbit	NNS
cord-017161-lcqrd4v0	272	9	,	,	,
cord-017161-lcqrd4v0	272	10	were	be	VBD
cord-017161-lcqrd4v0	272	11	able	able	JJ
cord-017161-lcqrd4v0	272	12	to	to	TO
cord-017161-lcqrd4v0	272	13	activate	activate	VB
cord-017161-lcqrd4v0	272	14	neutrophils	neutrophil	NNS
cord-017161-lcqrd4v0	272	15	and	and	CC
cord-017161-lcqrd4v0	272	16	induce	induce	VB
cord-017161-lcqrd4v0	272	17	apoptosis	apoptosis	NN
cord-017161-lcqrd4v0	272	18	of	of	IN
cord-017161-lcqrd4v0	272	19	human	human	JJ
cord-017161-lcqrd4v0	272	20	microvascular	microvascular	JJ
cord-017161-lcqrd4v0	272	21	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	272	22	cells	cell	NNS
cord-017161-lcqrd4v0	272	23	[	[	-LRB-
cord-017161-lcqrd4v0	272	24	142	142	CD
cord-017161-lcqrd4v0	272	25	]	]	-RRB-
cord-017161-lcqrd4v0	272	26	.	.	.
cord-017161-lcqrd4v0	273	1	More	more	RBR
cord-017161-lcqrd4v0	273	2	importantly	importantly	RB
cord-017161-lcqrd4v0	273	3	,	,	,
cord-017161-lcqrd4v0	273	4	these	these	DT
cord-017161-lcqrd4v0	273	5	antibodies	antibody	NNS
cord-017161-lcqrd4v0	273	6	induced	induce	VBD
cord-017161-lcqrd4v0	273	7	pauci	pauci	NN
cord-017161-lcqrd4v0	273	8	-	-	HYPH
cord-017161-lcqrd4v0	273	9	immune	immune	JJ
cord-017161-lcqrd4v0	273	10	focal	focal	JJ
cord-017161-lcqrd4v0	273	11	necrotizing	necrotize	VBG
cord-017161-lcqrd4v0	273	12	glomerulonephritis	glomerulonephritis	NN
cord-017161-lcqrd4v0	273	13	when	when	WRB
cord-017161-lcqrd4v0	273	14	injected	inject	VBN
cord-017161-lcqrd4v0	273	15	into	into	IN
cord-017161-lcqrd4v0	273	16	rats	rat	NNS
cord-017161-lcqrd4v0	273	17	[	[	-LRB-
cord-017161-lcqrd4v0	273	18	142	142	CD
cord-017161-lcqrd4v0	273	19	]	]	-RRB-
cord-017161-lcqrd4v0	273	20	.	.	.
cord-017161-lcqrd4v0	274	1	Eight	eight	CD
cord-017161-lcqrd4v0	274	2	out	out	IN
cord-017161-lcqrd4v0	274	3	of	of	IN
cord-017161-lcqrd4v0	274	4	nine	nine	CD
cord-017161-lcqrd4v0	274	5	amino	amino	JJ
cord-017161-lcqrd4v0	274	6	acids	acid	NNS
cord-017161-lcqrd4v0	274	7	of	of	IN
cord-017161-lcqrd4v0	274	8	the	the	DT
cord-017161-lcqrd4v0	274	9	P41	P41	NNP
cord-017161-lcqrd4v0	274	10	-	-	HYPH
cord-017161-lcqrd4v0	274	11	49	49	CD
cord-017161-lcqrd4v0	274	12	immunodominant	immunodominant	JJ
cord-017161-lcqrd4v0	274	13	epitope	epitope	NN
cord-017161-lcqrd4v0	274	14	of	of	IN
cord-017161-lcqrd4v0	274	15	hLAMP-2	hLAMP-2	NNP
cord-017161-lcqrd4v0	274	16	were	be	VBD
cord-017161-lcqrd4v0	274	17	shown	show	VBN
cord-017161-lcqrd4v0	274	18	to	to	TO
cord-017161-lcqrd4v0	274	19	be	be	VB
cord-017161-lcqrd4v0	274	20	identical	identical	JJ
cord-017161-lcqrd4v0	274	21	to	to	IN
cord-017161-lcqrd4v0	274	22	the	the	DT
cord-017161-lcqrd4v0	274	23	P72	P72	NNP
cord-017161-lcqrd4v0	274	24	-	-	HYPH
cord-017161-lcqrd4v0	274	25	80	80	CD
cord-017161-lcqrd4v0	274	26	peptide	peptide	NN
cord-017161-lcqrd4v0	274	27	of	of	IN
cord-017161-lcqrd4v0	274	28	FimH	FimH	NNP
cord-017161-lcqrd4v0	274	29	,	,	,
cord-017161-lcqrd4v0	274	30	an	an	DT
cord-017161-lcqrd4v0	274	31	adhesion	adhesion	NN
cord-017161-lcqrd4v0	274	32	molecule	molecule	NN
cord-017161-lcqrd4v0	274	33	of	of	IN
cord-017161-lcqrd4v0	274	34	fi	fi	NN
cord-017161-lcqrd4v0	274	35	mbriae	mbriae	FW
cord-017161-lcqrd4v0	274	36	of	of	IN
cord-017161-lcqrd4v0	274	37	Gram	Gram	NNP
cord-017161-lcqrd4v0	274	38	negative	negative	JJ
cord-017161-lcqrd4v0	274	39	bacteria	bacteria	NNS
cord-017161-lcqrd4v0	274	40	[	[	-LRB-
cord-017161-lcqrd4v0	274	41	142	142	CD
cord-017161-lcqrd4v0	274	42	]	]	-RRB-
cord-017161-lcqrd4v0	274	43	.	.	.
cord-017161-lcqrd4v0	275	1	Immunization	immunization	NN
cord-017161-lcqrd4v0	275	2	of	of	IN
cord-017161-lcqrd4v0	275	3	rats	rat	NNS
cord-017161-lcqrd4v0	275	4	with	with	IN
cord-017161-lcqrd4v0	275	5	FimH	FimH	NNP
cord-017161-lcqrd4v0	275	6	resulted	result	VBD
cord-017161-lcqrd4v0	275	7	in	in	IN
cord-017161-lcqrd4v0	275	8	the	the	DT
cord-017161-lcqrd4v0	275	9	generation	generation	NN
cord-017161-lcqrd4v0	275	10	of	of	IN
cord-017161-lcqrd4v0	275	11	antibodies	antibody	NNS
cord-017161-lcqrd4v0	275	12	cross	cross	NN
cord-017161-lcqrd4v0	275	13	-	-	NN
cord-017161-lcqrd4v0	275	14	reacting	react	VBG
cord-017161-lcqrd4v0	275	15	with	with	IN
cord-017161-lcqrd4v0	275	16	hLAMP-2	hLAMP-2	NNP
cord-017161-lcqrd4v0	275	17	and	and	CC
cord-017161-lcqrd4v0	275	18	inducing	induce	VBG
cord-017161-lcqrd4v0	275	19	pauci	pauci	NN
cord-017161-lcqrd4v0	275	20	-	-	HYPH
cord-017161-lcqrd4v0	275	21	immune	immune	JJ
cord-017161-lcqrd4v0	275	22	glomerulonephritis	glomerulonephritis	NN
cord-017161-lcqrd4v0	275	23	[	[	-LRB-
cord-017161-lcqrd4v0	275	24	142	142	CD
cord-017161-lcqrd4v0	275	25	]	]	-RRB-
cord-017161-lcqrd4v0	275	26	.	.	.
cord-017161-lcqrd4v0	276	1	These	these	DT
cord-017161-lcqrd4v0	276	2	observations	observation	NNS
cord-017161-lcqrd4v0	276	3	suggest	suggest	VBP
cord-017161-lcqrd4v0	276	4	that	that	IN
cord-017161-lcqrd4v0	276	5	infection	infection	NN
cord-017161-lcqrd4v0	276	6	with	with	IN
cord-017161-lcqrd4v0	276	7	Gram	Gram	NNP
cord-017161-lcqrd4v0	276	8	negative	negative	JJ
cord-017161-lcqrd4v0	276	9	bacteria	bacteria	NNS
cord-017161-lcqrd4v0	276	10	could	could	MD
cord-017161-lcqrd4v0	276	11	result	result	VB
cord-017161-lcqrd4v0	276	12	in	in	IN
cord-017161-lcqrd4v0	276	13	a	a	DT
cord-017161-lcqrd4v0	276	14	loss	loss	NN
cord-017161-lcqrd4v0	276	15	of	of	IN
cord-017161-lcqrd4v0	276	16	tolerance	tolerance	NN
cord-017161-lcqrd4v0	276	17	and	and	CC
cord-017161-lcqrd4v0	276	18	could	could	MD
cord-017161-lcqrd4v0	276	19	lead	lead	VB
cord-017161-lcqrd4v0	276	20	to	to	IN
cord-017161-lcqrd4v0	276	21	AAV	AAV	NNP
cord-017161-lcqrd4v0	276	22	.	.	.
cord-017161-lcqrd4v0	277	1	A	a	DT
cord-017161-lcqrd4v0	277	2	number	number	NN
cord-017161-lcqrd4v0	277	3	of	of	IN
cord-017161-lcqrd4v0	277	4	candidate	candidate	NN
cord-017161-lcqrd4v0	277	5	gene	gene	NNP
cord-017161-lcqrd4v0	277	6	association	association	NNP
cord-017161-lcqrd4v0	277	7	studies	study	NNS
cord-017161-lcqrd4v0	277	8	have	have	VBP
cord-017161-lcqrd4v0	277	9	identi	identi	NNP
cord-017161-lcqrd4v0	277	10	fi	fi	NNP
cord-017161-lcqrd4v0	277	11	ed	ed	NN
cord-017161-lcqrd4v0	277	12	variants	variant	NNS
cord-017161-lcqrd4v0	277	13	associated	associate	VBN
cord-017161-lcqrd4v0	277	14	with	with	IN
cord-017161-lcqrd4v0	277	15	an	an	DT
cord-017161-lcqrd4v0	277	16	increased	increase	VBN
cord-017161-lcqrd4v0	277	17	incidence	incidence	NN
cord-017161-lcqrd4v0	277	18	of	of	IN
cord-017161-lcqrd4v0	277	19	AAV	AAV	NNP
cord-017161-lcqrd4v0	277	20	[	[	-LRB-
cord-017161-lcqrd4v0	277	21	143	143	CD
cord-017161-lcqrd4v0	277	22	]	]	-RRB-
cord-017161-lcqrd4v0	277	23	.	.	.
cord-017161-lcqrd4v0	278	1	Most	Most	JJS
cord-017161-lcqrd4v0	278	2	of	of	IN
cord-017161-lcqrd4v0	278	3	the	the	DT
cord-017161-lcqrd4v0	278	4	genes	gene	NNS
cord-017161-lcqrd4v0	278	5	described	describe	VBN
cord-017161-lcqrd4v0	278	6	so	so	RB
cord-017161-lcqrd4v0	278	7	far	far	RB
cord-017161-lcqrd4v0	278	8	encode	encode	VBP
cord-017161-lcqrd4v0	278	9	proteins	protein	NNS
cord-017161-lcqrd4v0	278	10	involved	involve	VBN
cord-017161-lcqrd4v0	278	11	in	in	IN
cord-017161-lcqrd4v0	278	12	the	the	DT
cord-017161-lcqrd4v0	278	13	immune	immune	JJ
cord-017161-lcqrd4v0	278	14	response	response	NN
cord-017161-lcqrd4v0	278	15	and	and	CC
cord-017161-lcqrd4v0	278	16	are	be	VBP
cord-017161-lcqrd4v0	278	17	summarized	summarize	VBN
cord-017161-lcqrd4v0	278	18	in	in	IN
cord-017161-lcqrd4v0	278	19	Table	Table	NNP
cord-017161-lcqrd4v0	278	20	2	2	CD
cord-017161-lcqrd4v0	278	21	.	.	.
cord-017161-lcqrd4v0	279	1	3	3	LS
cord-017161-lcqrd4v0	279	2	.	.	.
cord-017161-lcqrd4v0	280	1	Of	of	IN
cord-017161-lcqrd4v0	280	2	note	note	NN
cord-017161-lcqrd4v0	280	3	,	,	,
cord-017161-lcqrd4v0	280	4	the	the	DT
cord-017161-lcqrd4v0	280	5	genes	gene	NNS
cord-017161-lcqrd4v0	280	6	with	with	IN
cord-017161-lcqrd4v0	280	7	variants	variant	NNS
cord-017161-lcqrd4v0	280	8	most	most	RBS
cord-017161-lcqrd4v0	280	9	strongly	strongly	RB
cord-017161-lcqrd4v0	280	10	associated	associate	VBN
cord-017161-lcqrd4v0	280	11	with	with	IN
cord-017161-lcqrd4v0	280	12	AAV	AAV	NNP
cord-017161-lcqrd4v0	280	13	,	,	,
cord-017161-lcqrd4v0	280	14	the	the	DT
cord-017161-lcqrd4v0	280	15	MHC	MHC	NNP
cord-017161-lcqrd4v0	280	16	and	and	CC
cord-017161-lcqrd4v0	280	17	PTPN22	ptpn22	CD
cord-017161-lcqrd4v0	280	18	genes	gene	NNS
cord-017161-lcqrd4v0	280	19	,	,	,
cord-017161-lcqrd4v0	280	20	also	also	RB
cord-017161-lcqrd4v0	280	21	have	have	VBP
cord-017161-lcqrd4v0	280	22	variants	variant	NNS
cord-017161-lcqrd4v0	280	23	associated	associate	VBN
cord-017161-lcqrd4v0	280	24	with	with	IN
cord-017161-lcqrd4v0	280	25	other	other	JJ
cord-017161-lcqrd4v0	280	26	autoimmune	autoimmune	JJ
cord-017161-lcqrd4v0	280	27	diseases	disease	NNS
cord-017161-lcqrd4v0	280	28	,	,	,
cord-017161-lcqrd4v0	280	29	including	include	VBG
cord-017161-lcqrd4v0	280	30	rheumatoid	rheumatoid	NN
cord-017161-lcqrd4v0	280	31	arthritis	arthritis	NN
cord-017161-lcqrd4v0	280	32	,	,	,
cord-017161-lcqrd4v0	280	33	type	type	NN
cord-017161-lcqrd4v0	280	34	1	1	CD
cord-017161-lcqrd4v0	280	35	diabetes	diabetes	NN
cord-017161-lcqrd4v0	280	36	and	and	CC
cord-017161-lcqrd4v0	280	37	systemic	systemic	JJ
cord-017161-lcqrd4v0	280	38	lupus	lupus	NN
cord-017161-lcqrd4v0	280	39	erythematosus	erythematosus	NN
cord-017161-lcqrd4v0	280	40	(	(	-LRB-
cord-017161-lcqrd4v0	280	41	SLE	SLE	NNP
cord-017161-lcqrd4v0	280	42	)	)	-RRB-
cord-017161-lcqrd4v0	280	43	[	[	-LRB-
cord-017161-lcqrd4v0	280	44	143	143	CD
cord-017161-lcqrd4v0	280	45	]	]	-RRB-
cord-017161-lcqrd4v0	280	46	.	.	.
cord-017161-lcqrd4v0	281	1	This	this	DT
cord-017161-lcqrd4v0	281	2	suggests	suggest	VBZ
cord-017161-lcqrd4v0	281	3	that	that	IN
cord-017161-lcqrd4v0	281	4	genetic	genetic	JJ
cord-017161-lcqrd4v0	281	5	risk	risk	NN
cord-017161-lcqrd4v0	281	6	factors	factor	NNS
cord-017161-lcqrd4v0	281	7	common	common	JJ
cord-017161-lcqrd4v0	281	8	to	to	IN
cord-017161-lcqrd4v0	281	9	other	other	JJ
cord-017161-lcqrd4v0	281	10	autoimmune	autoimmune	JJ
cord-017161-lcqrd4v0	281	11	diseases	disease	NNS
cord-017161-lcqrd4v0	281	12	also	also	RB
cord-017161-lcqrd4v0	281	13	apply	apply	VBP
cord-017161-lcqrd4v0	281	14	to	to	IN
cord-017161-lcqrd4v0	281	15	AAV	AAV	NNP
cord-017161-lcqrd4v0	281	16	.	.	.
cord-017161-lcqrd4v0	282	1	Different	different	JJ
cord-017161-lcqrd4v0	282	2	variants	variant	NNS
cord-017161-lcqrd4v0	282	3	within	within	IN
cord-017161-lcqrd4v0	282	4	each	each	DT
cord-017161-lcqrd4v0	282	5	gene	gene	NN
cord-017161-lcqrd4v0	282	6	may	may	MD
cord-017161-lcqrd4v0	282	7	be	be	VB
cord-017161-lcqrd4v0	282	8	associated	associate	VBN
cord-017161-lcqrd4v0	282	9	with	with	IN
cord-017161-lcqrd4v0	282	10	different	different	JJ
cord-017161-lcqrd4v0	282	11	polymorphisms	polymorphism	NNS
cord-017161-lcqrd4v0	282	12	-	-	,
cord-017161-lcqrd4v0	282	13	for	for	RP
cord-017161-lcqrd4v0	282	14	example	example	NN
cord-017161-lcqrd4v0	282	15	,	,	,
cord-017161-lcqrd4v0	282	16	SLE	SLE	NNP
cord-017161-lcqrd4v0	282	17	associates	associate	NNS
cord-017161-lcqrd4v0	282	18	with	with	IN
cord-017161-lcqrd4v0	282	19	the	the	DT
cord-017161-lcqrd4v0	282	20	IL-2RA	il-2ra	NN
cord-017161-lcqrd4v0	282	21	SNP	SNP	NNP
cord-017161-lcqrd4v0	282	22	rs11594656	rs11594656	NNP
cord-017161-lcqrd4v0	282	23	,	,	,
cord-017161-lcqrd4v0	282	24	while	while	IN
cord-017161-lcqrd4v0	282	25	AAV	AAV	NNP
cord-017161-lcqrd4v0	282	26	is	be	VBZ
cord-017161-lcqrd4v0	282	27	associated	associate	VBN
cord-017161-lcqrd4v0	282	28	with	with	IN
cord-017161-lcqrd4v0	282	29	rs4129506	rs4129506	NNP
cord-017161-lcqrd4v0	282	30	[	[	-LRB-
cord-017161-lcqrd4v0	282	31	143	143	CD
cord-017161-lcqrd4v0	282	32	]	]	-RRB-
cord-017161-lcqrd4v0	282	33	.	.	.
cord-017161-lcqrd4v0	283	1	A	a	DT
cord-017161-lcqrd4v0	283	2	GWAS	GWAS	NNP
cord-017161-lcqrd4v0	283	3	of	of	IN
cord-017161-lcqrd4v0	283	4	AAV	AAV	NNP
cord-017161-lcqrd4v0	283	5	is	be	VBZ
cord-017161-lcqrd4v0	283	6	currently	currently	RB
cord-017161-lcqrd4v0	283	7	ongoing	ongoing	JJ
cord-017161-lcqrd4v0	283	8	and	and	CC
cord-017161-lcqrd4v0	283	9	may	may	MD
cord-017161-lcqrd4v0	283	10	be	be	VB
cord-017161-lcqrd4v0	283	11	enlightening	enlightening	JJ
cord-017161-lcqrd4v0	283	12	in	in	IN
cord-017161-lcqrd4v0	283	13	that	that	DT
cord-017161-lcqrd4v0	283	14	respect	respect	NN
cord-017161-lcqrd4v0	283	15	.	.	.
cord-017161-lcqrd4v0	284	1	Furthermore	furthermore	RB
cord-017161-lcqrd4v0	284	2	,	,	,
cord-017161-lcqrd4v0	284	3	Ciavatta	Ciavatta	NNP
cord-017161-lcqrd4v0	284	4	et	et	NNP
cord-017161-lcqrd4v0	284	5	al	al	NNP
cord-017161-lcqrd4v0	284	6	.	.	NNP
cord-017161-lcqrd4v0	284	7	,	,	,
cord-017161-lcqrd4v0	284	8	in	in	IN
cord-017161-lcqrd4v0	284	9	an	an	DT
cord-017161-lcqrd4v0	284	10	attempt	attempt	NN
cord-017161-lcqrd4v0	284	11	to	to	TO
cord-017161-lcqrd4v0	284	12	uncover	uncover	VB
cord-017161-lcqrd4v0	284	13	a	a	DT
cord-017161-lcqrd4v0	284	14	potential	potential	JJ
cord-017161-lcqrd4v0	284	15	transcriptional	transcriptional	JJ
cord-017161-lcqrd4v0	284	16	regulatory	regulatory	JJ
cord-017161-lcqrd4v0	284	17	mechanism	mechanism	NN
cord-017161-lcqrd4v0	284	18	for	for	IN
cord-017161-lcqrd4v0	284	19	PR3	PR3	NNP
cord-017161-lcqrd4v0	284	20	and	and	CC
cord-017161-lcqrd4v0	284	21	MPO	MPO	NNP
cord-017161-lcqrd4v0	284	22	disrupted	disrupt	VBD
cord-017161-lcqrd4v0	284	23	in	in	IN
cord-017161-lcqrd4v0	284	24	patients	patient	NNS
cord-017161-lcqrd4v0	284	25	with	with	IN
cord-017161-lcqrd4v0	284	26	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	284	27	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	284	28	,	,	,
cord-017161-lcqrd4v0	284	29	examined	examine	VBD
cord-017161-lcqrd4v0	284	30	the	the	DT
cord-017161-lcqrd4v0	284	31	PR3	PR3	NNP
cord-017161-lcqrd4v0	284	32	and	and	CC
cord-017161-lcqrd4v0	284	33	MPO	MPO	NNP
cord-017161-lcqrd4v0	284	34	loci	locus	NNS
cord-017161-lcqrd4v0	284	35	in	in	IN
cord-017161-lcqrd4v0	284	36	neutrophils	neutrophil	NNS
cord-017161-lcqrd4v0	284	37	from	from	IN
cord-017161-lcqrd4v0	284	38	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	284	39	patients	patient	NNS
cord-017161-lcqrd4v0	284	40	and	and	CC
cord-017161-lcqrd4v0	284	41	healthy	healthy	JJ
cord-017161-lcqrd4v0	284	42	control	control	NN
cord-017161-lcqrd4v0	284	43	individuals	individual	NNS
cord-017161-lcqrd4v0	284	44	for	for	IN
cord-017161-lcqrd4v0	284	45	epigenetic	epigenetic	JJ
cord-017161-lcqrd4v0	284	46	modi	modi	NNP
cord-017161-lcqrd4v0	284	47	fi	fi	NN
cord-017161-lcqrd4v0	284	48	cations	cation	NNS
cord-017161-lcqrd4v0	284	49	associated	associate	VBN
cord-017161-lcqrd4v0	284	50	with	with	IN
cord-017161-lcqrd4v0	284	51	gene	gene	NN
cord-017161-lcqrd4v0	284	52	silencing	silence	VBG
cord-017161-lcqrd4v0	284	53	[	[	-LRB-
cord-017161-lcqrd4v0	284	54	173	173	CD
cord-017161-lcqrd4v0	284	55	]	]	-RRB-
cord-017161-lcqrd4v0	284	56	.	.	.
cord-017161-lcqrd4v0	285	1	They	-PRON-	PRP
cord-017161-lcqrd4v0	285	2	demonstrated	demonstrate	VBD
cord-017161-lcqrd4v0	285	3	that	that	IN
cord-017161-lcqrd4v0	285	4	levels	level	NNS
cord-017161-lcqrd4v0	285	5	of	of	IN
cord-017161-lcqrd4v0	285	6	the	the	DT
cord-017161-lcqrd4v0	285	7	chromatin	chromatin	FW
cord-017161-lcqrd4v0	285	8	modi	modi	NNP
cord-017161-lcqrd4v0	285	9	fi	fi	NNP
cord-017161-lcqrd4v0	285	10	cation	cation	NN
cord-017161-lcqrd4v0	285	11	H3K27me3	H3K27me3	NNP
cord-017161-lcqrd4v0	285	12	,	,	,
cord-017161-lcqrd4v0	285	13	which	which	WDT
cord-017161-lcqrd4v0	285	14	is	be	VBZ
cord-017161-lcqrd4v0	285	15	associated	associate	VBN
cord-017161-lcqrd4v0	285	16	with	with	IN
cord-017161-lcqrd4v0	285	17	gene	gene	NN
cord-017161-lcqrd4v0	285	18	silencing	silencing	NN
cord-017161-lcqrd4v0	285	19	,	,	,
cord-017161-lcqrd4v0	285	20	were	be	VBD
cord-017161-lcqrd4v0	285	21	depleted	deplete	VBN
cord-017161-lcqrd4v0	285	22	at	at	IN
cord-017161-lcqrd4v0	285	23	PR3	PR3	NNP
cord-017161-lcqrd4v0	285	24	and	and	CC
cord-017161-lcqrd4v0	285	25	MPO	MPO	NNP
cord-017161-lcqrd4v0	285	26	loci	locus	NNS
cord-017161-lcqrd4v0	285	27	in	in	IN
cord-017161-lcqrd4v0	285	28	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	285	29	patients	patient	NNS
cord-017161-lcqrd4v0	285	30	compared	compare	VBN
cord-017161-lcqrd4v0	285	31	with	with	IN
cord-017161-lcqrd4v0	285	32	healthy	healthy	JJ
cord-017161-lcqrd4v0	285	33	controls	control	NNS
cord-017161-lcqrd4v0	285	34	[	[	-LRB-
cord-017161-lcqrd4v0	285	35	173	173	CD
cord-017161-lcqrd4v0	285	36	]	]	-RRB-
cord-017161-lcqrd4v0	285	37	.	.	.
cord-017161-lcqrd4v0	286	1	Interestingly	interestingly	RB
cord-017161-lcqrd4v0	286	2	,	,	,
cord-017161-lcqrd4v0	286	3	in	in	IN
cord-017161-lcqrd4v0	286	4	both	both	DT
cord-017161-lcqrd4v0	286	5	patients	patient	NNS
cord-017161-lcqrd4v0	286	6	and	and	CC
cord-017161-lcqrd4v0	286	7	controls	control	NNS
cord-017161-lcqrd4v0	286	8	,	,	,
cord-017161-lcqrd4v0	286	9	DNA	DNA	NNP
cord-017161-lcqrd4v0	286	10	was	be	VBD
cord-017161-lcqrd4v0	286	11	unmethylated	unmethylate	VBN
cord-017161-lcqrd4v0	286	12	at	at	IN
cord-017161-lcqrd4v0	286	13	a	a	DT
cord-017161-lcqrd4v0	286	14	CpG	CpG	NNP
cord-017161-lcqrd4v0	286	15	island	island	NN
cord-017161-lcqrd4v0	286	16	in	in	IN
cord-017161-lcqrd4v0	286	17	PR3	PR3	NNP
cord-017161-lcqrd4v0	286	18	,	,	,
cord-017161-lcqrd4v0	286	19	whereas	whereas	IN
cord-017161-lcqrd4v0	286	20	in	in	IN
cord-017161-lcqrd4v0	286	21	healthy	healthy	JJ
cord-017161-lcqrd4v0	286	22	controls	control	NNS
cord-017161-lcqrd4v0	286	23	,	,	,
cord-017161-lcqrd4v0	286	24	DNA	DNA	NNP
cord-017161-lcqrd4v0	286	25	was	be	VBD
cord-017161-lcqrd4v0	286	26	methylated	methylate	VBN
cord-017161-lcqrd4v0	286	27	at	at	IN
cord-017161-lcqrd4v0	286	28	a	a	DT
cord-017161-lcqrd4v0	286	29	CpG	CpG	NNP
cord-017161-lcqrd4v0	286	30	island	island	NN
cord-017161-lcqrd4v0	286	31	in	in	IN
cord-017161-lcqrd4v0	286	32	MPO	MPO	NNP
cord-017161-lcqrd4v0	286	33	[	[	-LRB-
cord-017161-lcqrd4v0	286	34	173	173	CD
cord-017161-lcqrd4v0	286	35	]	]	-RRB-
cord-017161-lcqrd4v0	286	36	.	.	.
cord-017161-lcqrd4v0	287	1	Consistent	consistent	JJ
cord-017161-lcqrd4v0	287	2	with	with	IN
cord-017161-lcqrd4v0	287	3	decreased	decrease	VBN
cord-017161-lcqrd4v0	287	4	levels	level	NNS
cord-017161-lcqrd4v0	287	5	of	of	IN
cord-017161-lcqrd4v0	287	6	H3K27me3	H3K27me3	NNP
cord-017161-lcqrd4v0	287	7	,	,	,
cord-017161-lcqrd4v0	287	8	JMJD3	JMJD3	NNP
cord-017161-lcqrd4v0	287	9	,	,	,
cord-017161-lcqrd4v0	287	10	the	the	DT
cord-017161-lcqrd4v0	287	11	demethylase	demethylase	FW
cord-017161-lcqrd4v0	287	12	speci	speci	NNP
cord-017161-lcqrd4v0	287	13	fi	fi	NN
cord-017161-lcqrd4v0	287	14	c	c	NN
cord-017161-lcqrd4v0	287	15	for	for	IN
cord-017161-lcqrd4v0	287	16	H3K27me3	H3K27me3	NNP
cord-017161-lcqrd4v0	287	17	,	,	,
cord-017161-lcqrd4v0	287	18	was	be	VBD
cord-017161-lcqrd4v0	287	19	preferentially	preferentially	RB
cord-017161-lcqrd4v0	287	20	expressed	express	VBN
cord-017161-lcqrd4v0	287	21	in	in	IN
cord-017161-lcqrd4v0	287	22	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	287	23	patients	patient	NNS
cord-017161-lcqrd4v0	287	24	versus	versus	IN
cord-017161-lcqrd4v0	287	25	healthy	healthy	JJ
cord-017161-lcqrd4v0	287	26	controls	control	NNS
cord-017161-lcqrd4v0	287	27	[	[	-LRB-
cord-017161-lcqrd4v0	287	28	173	173	CD
cord-017161-lcqrd4v0	287	29	]	]	-RRB-
cord-017161-lcqrd4v0	287	30	.	.	.
cord-017161-lcqrd4v0	288	1	In	in	IN
cord-017161-lcqrd4v0	288	2	addition	addition	NN
cord-017161-lcqrd4v0	288	3	,	,	,
cord-017161-lcqrd4v0	288	4	the	the	DT
cord-017161-lcqrd4v0	288	5	mechanism	mechanism	NN
cord-017161-lcqrd4v0	288	6	for	for	IN
cord-017161-lcqrd4v0	288	7	recruiting	recruit	VBG
cord-017161-lcqrd4v0	288	8	the	the	DT
cord-017161-lcqrd4v0	288	9	H3K27	H3K27	NNP
cord-017161-lcqrd4v0	288	10	methyltransferase	methyltransferase	NN
cord-017161-lcqrd4v0	288	11	enhancer	enhancer	NN
cord-017161-lcqrd4v0	288	12	of	of	IN
cord-017161-lcqrd4v0	288	13	zeste	zeste	NNP
cord-017161-lcqrd4v0	288	14	homolog	homolog	NNP
cord-017161-lcqrd4v0	288	15	2	2	CD
cord-017161-lcqrd4v0	288	16	(	(	-LRB-
cord-017161-lcqrd4v0	288	17	EZH2	ezh2	NN
cord-017161-lcqrd4v0	288	18	)	)	-RRB-
cord-017161-lcqrd4v0	288	19	to	to	IN
cord-017161-lcqrd4v0	288	20	PR3	PR3	NNP
cord-017161-lcqrd4v0	288	21	and	and	CC
cord-017161-lcqrd4v0	288	22	MPO	MPO	NNP
cord-017161-lcqrd4v0	288	23	loci	locus	NNS
cord-017161-lcqrd4v0	288	24	was	be	VBD
cord-017161-lcqrd4v0	288	25	shown	show	VBN
cord-017161-lcqrd4v0	288	26	to	to	TO
cord-017161-lcqrd4v0	288	27	be	be	VB
cord-017161-lcqrd4v0	288	28	mediated	mediate	VBN
cord-017161-lcqrd4v0	288	29	by	by	IN
cord-017161-lcqrd4v0	288	30	RUNX3	RUNX3	NNP
cord-017161-lcqrd4v0	288	31	.	.	.
cord-017161-lcqrd4v0	289	1	RUNX3	RUNX3	NNP
cord-017161-lcqrd4v0	289	2	message	message	NN
cord-017161-lcqrd4v0	289	3	was	be	VBD
cord-017161-lcqrd4v0	289	4	decreased	decrease	VBN
cord-017161-lcqrd4v0	289	5	in	in	IN
cord-017161-lcqrd4v0	289	6	patients	patient	NNS
cord-017161-lcqrd4v0	289	7	compared	compare	VBN
cord-017161-lcqrd4v0	289	8	with	with	IN
cord-017161-lcqrd4v0	289	9	healthy	healthy	JJ
cord-017161-lcqrd4v0	289	10	controls	control	NNS
cord-017161-lcqrd4v0	289	11	,	,	,
cord-017161-lcqrd4v0	289	12	and	and	CC
cord-017161-lcqrd4v0	289	13	may	may	MD
cord-017161-lcqrd4v0	289	14	also	also	RB
cord-017161-lcqrd4v0	289	15	be	be	VB
cord-017161-lcqrd4v0	289	16	under	under	IN
cord-017161-lcqrd4v0	289	17	epigenetic	epigenetic	JJ
cord-017161-lcqrd4v0	289	18	control	control	NN
cord-017161-lcqrd4v0	289	19	[	[	-LRB-
cord-017161-lcqrd4v0	289	20	173	173	CD
cord-017161-lcqrd4v0	289	21	]	]	-RRB-
cord-017161-lcqrd4v0	289	22	.	.	.
cord-017161-lcqrd4v0	290	1	DNA	dna	NN
cord-017161-lcqrd4v0	290	2	methylation	methylation	NN
cord-017161-lcqrd4v0	290	3	was	be	VBD
cord-017161-lcqrd4v0	290	4	increased	increase	VBN
cord-017161-lcqrd4v0	290	5	at	at	IN
cord-017161-lcqrd4v0	290	6	the	the	DT
cord-017161-lcqrd4v0	290	7	RUNX3	RUNX3	NNP
cord-017161-lcqrd4v0	290	8	promoter	promoter	NN
cord-017161-lcqrd4v0	290	9	in	in	IN
cord-017161-lcqrd4v0	290	10	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	290	11	patients	patient	NNS
cord-017161-lcqrd4v0	290	12	[	[	-LRB-
cord-017161-lcqrd4v0	290	13	173	173	CD
cord-017161-lcqrd4v0	290	14	]	]	-RRB-
cord-017161-lcqrd4v0	290	15	.	.	.
cord-017161-lcqrd4v0	291	1	These	these	DT
cord-017161-lcqrd4v0	291	2	data	datum	NNS
cord-017161-lcqrd4v0	291	3	indicate	indicate	VBP
cord-017161-lcqrd4v0	291	4	that	that	IN
cord-017161-lcqrd4v0	291	5	epigenetic	epigenetic	JJ
cord-017161-lcqrd4v0	291	6	modi	modi	NNP
cord-017161-lcqrd4v0	291	7	fi	fi	NN
cord-017161-lcqrd4v0	291	8	cations	cation	NNS
cord-017161-lcqrd4v0	291	9	associated	associate	VBN
cord-017161-lcqrd4v0	291	10	with	with	IN
cord-017161-lcqrd4v0	291	11	gene	gene	NN
cord-017161-lcqrd4v0	291	12	silencing	silencing	NN
cord-017161-lcqrd4v0	291	13	are	be	VBP
cord-017161-lcqrd4v0	291	14	perturbed	perturb	VBN
cord-017161-lcqrd4v0	291	15	at	at	IN
cord-017161-lcqrd4v0	291	16	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	291	17	autoantigen	autoantigen	NN
cord-017161-lcqrd4v0	291	18	-	-	HYPH
cord-017161-lcqrd4v0	291	19	encoding	encode	VBG
cord-017161-lcqrd4v0	291	20	genes	gene	NNS
cord-017161-lcqrd4v0	291	21	,	,	,
cord-017161-lcqrd4v0	291	22	potentially	potentially	RB
cord-017161-lcqrd4v0	291	23	contributing	contribute	VBG
cord-017161-lcqrd4v0	291	24	to	to	IN
cord-017161-lcqrd4v0	291	25	inappropriate	inappropriate	JJ
cord-017161-lcqrd4v0	291	26	expression	expression	NN
cord-017161-lcqrd4v0	291	27	of	of	IN
cord-017161-lcqrd4v0	291	28	PR3	PR3	NNP
cord-017161-lcqrd4v0	291	29	and	and	CC
cord-017161-lcqrd4v0	291	30	MPO	MPO	NNP
cord-017161-lcqrd4v0	291	31	in	in	IN
cord-017161-lcqrd4v0	291	32	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	291	33	patients	patient	NNS
cord-017161-lcqrd4v0	291	34	[	[	-LRB-
cord-017161-lcqrd4v0	291	35	173	173	CD
cord-017161-lcqrd4v0	291	36	]	]	-RRB-
cord-017161-lcqrd4v0	291	37	.	.	.
cord-017161-lcqrd4v0	292	1	WG	WG	NNP
cord-017161-lcqrd4v0	292	2	typically	typically	RB
cord-017161-lcqrd4v0	292	3	affects	affect	VBZ
cord-017161-lcqrd4v0	292	4	the	the	DT
cord-017161-lcqrd4v0	292	5	upper	upper	JJ
cord-017161-lcqrd4v0	292	6	and	and	CC
cord-017161-lcqrd4v0	292	7	lower	low	JJR
cord-017161-lcqrd4v0	292	8	respiratory	respiratory	JJ
cord-017161-lcqrd4v0	292	9	tract	tract	NN
cord-017161-lcqrd4v0	292	10	and	and	CC
cord-017161-lcqrd4v0	292	11	is	be	VBZ
cord-017161-lcqrd4v0	292	12	associated	associate	VBN
cord-017161-lcqrd4v0	292	13	with	with	IN
cord-017161-lcqrd4v0	292	14	glomerulonephritis	glomerulonephritis	NN
cord-017161-lcqrd4v0	292	15	,	,	,
cord-017161-lcqrd4v0	292	16	although	although	IN
cord-017161-lcqrd4v0	292	17	the	the	DT
cord-017161-lcqrd4v0	292	18	disease	disease	NN
cord-017161-lcqrd4v0	292	19	can	can	MD
cord-017161-lcqrd4v0	292	20	affect	affect	VB
cord-017161-lcqrd4v0	292	21	any	any	DT
cord-017161-lcqrd4v0	292	22	organ	organ	NN
cord-017161-lcqrd4v0	292	23	system	system	NN
cord-017161-lcqrd4v0	292	24	in	in	IN
cord-017161-lcqrd4v0	292	25	the	the	DT
cord-017161-lcqrd4v0	292	26	body	body	NN
cord-017161-lcqrd4v0	292	27	[	[	-LRB-
cord-017161-lcqrd4v0	292	28	34	34	CD
cord-017161-lcqrd4v0	292	29	]	]	-RRB-
cord-017161-lcqrd4v0	292	30	.	.	.
cord-017161-lcqrd4v0	293	1	From	from	IN
cord-017161-lcqrd4v0	293	2	a	a	DT
cord-017161-lcqrd4v0	293	3	clinical	clinical	JJ
cord-017161-lcqrd4v0	293	4	perspective	perspective	NN
cord-017161-lcqrd4v0	293	5	,	,	,
cord-017161-lcqrd4v0	293	6	it	-PRON-	PRP
cord-017161-lcqrd4v0	293	7	may	may	MD
cord-017161-lcqrd4v0	293	8	be	be	VB
cord-017161-lcqrd4v0	293	9	useful	useful	JJ
cord-017161-lcqrd4v0	293	10	to	to	TO
cord-017161-lcqrd4v0	293	11	think	think	VB
cord-017161-lcqrd4v0	293	12	of	of	IN
cord-017161-lcqrd4v0	293	13	WG	WG	NNP
cord-017161-lcqrd4v0	293	14	as	as	IN
cord-017161-lcqrd4v0	293	15	having	have	VBG
cord-017161-lcqrd4v0	293	16	two	two	CD
cord-017161-lcqrd4v0	293	17	forms	form	NNS
cord-017161-lcqrd4v0	293	18	:	:	:
cord-017161-lcqrd4v0	293	19	a	a	DT
cord-017161-lcqrd4v0	293	20	predominantly	predominantly	RB
cord-017161-lcqrd4v0	293	21	granulomatous	granulomatous	JJ
cord-017161-lcqrd4v0	293	22	form	form	NN
cord-017161-lcqrd4v0	293	23	with	with	IN
cord-017161-lcqrd4v0	293	24	mainly	mainly	RB
cord-017161-lcqrd4v0	293	25	localized	localize	VBN
cord-017161-lcqrd4v0	293	26	disease	disease	NN
cord-017161-lcqrd4v0	293	27	with	with	IN
cord-017161-lcqrd4v0	293	28	a	a	DT
cord-017161-lcqrd4v0	293	29	[	[	-LRB-
cord-017161-lcqrd4v0	293	30	172	172	CD
cord-017161-lcqrd4v0	293	31	]	]	-RRB-
cord-017161-lcqrd4v0	293	32	chronic	chronic	JJ
cord-017161-lcqrd4v0	293	33	course	course	NN
cord-017161-lcqrd4v0	293	34	;	;	:
cord-017161-lcqrd4v0	293	35	and	and	CC
cord-017161-lcqrd4v0	293	36	a	a	DT
cord-017161-lcqrd4v0	293	37	fl	fl	NNP
cord-017161-lcqrd4v0	293	38	orid	orid	NN
cord-017161-lcqrd4v0	293	39	,	,	,
cord-017161-lcqrd4v0	293	40	acute	acute	JJ
cord-017161-lcqrd4v0	293	41	small	small	JJ
cord-017161-lcqrd4v0	293	42	vessel	vessel	NN
cord-017161-lcqrd4v0	293	43	vasculitic	vasculitic	JJ
cord-017161-lcqrd4v0	293	44	form	form	NN
cord-017161-lcqrd4v0	293	45	characterized	characterize	VBN
cord-017161-lcqrd4v0	293	46	by	by	IN
cord-017161-lcqrd4v0	293	47	severe	severe	JJ
cord-017161-lcqrd4v0	293	48	pulmonary	pulmonary	JJ
cord-017161-lcqrd4v0	293	49	haemorrhage	haemorrhage	NN
cord-017161-lcqrd4v0	293	50	and/or	and/or	CC
cord-017161-lcqrd4v0	293	51	rapidly	rapidly	RB
cord-017161-lcqrd4v0	293	52	progressive	progressive	JJ
cord-017161-lcqrd4v0	293	53	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	293	54	or	or	CC
cord-017161-lcqrd4v0	293	55	other	other	JJ
cord-017161-lcqrd4v0	293	56	severe	severe	JJ
cord-017161-lcqrd4v0	293	57	vasculitic	vasculitic	JJ
cord-017161-lcqrd4v0	293	58	manifestation	manifestation	NN
cord-017161-lcqrd4v0	293	59	[	[	-LRB-
cord-017161-lcqrd4v0	293	60	34	34	CD
cord-017161-lcqrd4v0	293	61	]	]	-RRB-
cord-017161-lcqrd4v0	293	62	.	.	.
cord-017161-lcqrd4v0	294	1	These	these	DT
cord-017161-lcqrd4v0	294	2	two	two	CD
cord-017161-lcqrd4v0	294	3	broad	broad	JJ
cord-017161-lcqrd4v0	294	4	presentations	presentation	NNS
cord-017161-lcqrd4v0	294	5	may	may	MD
cord-017161-lcqrd4v0	294	6	coexist	coexist	VB
cord-017161-lcqrd4v0	294	7	or	or	CC
cord-017161-lcqrd4v0	294	8	present	present	VB
cord-017161-lcqrd4v0	294	9	sequentially	sequentially	RB
cord-017161-lcqrd4v0	294	10	in	in	IN
cord-017161-lcqrd4v0	294	11	individual	individual	JJ
cord-017161-lcqrd4v0	294	12	patients	patient	NNS
cord-017161-lcqrd4v0	294	13	.	.	.
cord-017161-lcqrd4v0	295	1	Symptoms	symptom	NNS
cord-017161-lcqrd4v0	295	2	and	and	CC
cord-017161-lcqrd4v0	295	3	signs	sign	NNS
cord-017161-lcqrd4v0	295	4	of	of	IN
cord-017161-lcqrd4v0	295	5	upper	upper	JJ
cord-017161-lcqrd4v0	295	6	respiratory	respiratory	JJ
cord-017161-lcqrd4v0	295	7	tract	tract	NN
cord-017161-lcqrd4v0	295	8	involvement	involvement	NN
cord-017161-lcqrd4v0	295	9	include	include	VBP
cord-017161-lcqrd4v0	295	10	epistaxis	epistaxis	NNP
cord-017161-lcqrd4v0	295	11	,	,	,
cord-017161-lcqrd4v0	295	12	otalgia	otalgia	NNP
cord-017161-lcqrd4v0	295	13	and	and	CC
cord-017161-lcqrd4v0	295	14	hearing	hear	VBG
cord-017161-lcqrd4v0	295	15	loss	loss	NN
cord-017161-lcqrd4v0	295	16	(	(	-LRB-
cord-017161-lcqrd4v0	295	17	conductive	conductive	JJ
cord-017161-lcqrd4v0	295	18	and	and	CC
cord-017161-lcqrd4v0	295	19	sensorineural	sensorineural	JJ
cord-017161-lcqrd4v0	295	20	)	)	-RRB-
cord-017161-lcqrd4v0	295	21	[	[	-LRB-
cord-017161-lcqrd4v0	295	22	34	34	CD
cord-017161-lcqrd4v0	295	23	]	]	-RRB-
cord-017161-lcqrd4v0	295	24	.	.	.
cord-017161-lcqrd4v0	296	1	Nasal	nasal	JJ
cord-017161-lcqrd4v0	296	2	septal	septal	JJ
cord-017161-lcqrd4v0	296	3	involvement	involvement	NN
cord-017161-lcqrd4v0	296	4	with	with	IN
cord-017161-lcqrd4v0	296	5	cartilaginous	cartilaginous	JJ
cord-017161-lcqrd4v0	296	6	collapse	collapse	NN
cord-017161-lcqrd4v0	296	7	results	result	NNS
cord-017161-lcqrd4v0	296	8	in	in	IN
cord-017161-lcqrd4v0	296	9	the	the	DT
cord-017161-lcqrd4v0	296	10	characteristic	characteristic	JJ
cord-017161-lcqrd4v0	296	11	saddle	saddle	NN
cord-017161-lcqrd4v0	296	12	nose	nose	NN
cord-017161-lcqrd4v0	296	13	deformity	deformity	NN
cord-017161-lcqrd4v0	296	14	,	,	,
cord-017161-lcqrd4v0	296	15	although	although	IN
cord-017161-lcqrd4v0	296	16	this	this	DT
cord-017161-lcqrd4v0	296	17	may	may	MD
cord-017161-lcqrd4v0	296	18	not	not	RB
cord-017161-lcqrd4v0	296	19	be	be	VB
cord-017161-lcqrd4v0	296	20	present	present	JJ
cord-017161-lcqrd4v0	296	21	at	at	IN
cord-017161-lcqrd4v0	296	22	initial	initial	JJ
cord-017161-lcqrd4v0	296	23	presentation	presentation	NN
cord-017161-lcqrd4v0	296	24	[	[	-LRB-
cord-017161-lcqrd4v0	296	25	34	34	CD
cord-017161-lcqrd4v0	296	26	]	]	-RRB-
cord-017161-lcqrd4v0	296	27	.	.	.
cord-017161-lcqrd4v0	297	1	Chronic	chronic	JJ
cord-017161-lcqrd4v0	297	2	sinusitis	sinusitis	NN
cord-017161-lcqrd4v0	297	3	may	may	MD
cord-017161-lcqrd4v0	297	4	be	be	VB
cord-017161-lcqrd4v0	297	5	observed	observe	VBN
cord-017161-lcqrd4v0	297	6	.	.	.
cord-017161-lcqrd4v0	298	1	Glottic	glottic	JJ
cord-017161-lcqrd4v0	298	2	and	and	CC
cord-017161-lcqrd4v0	298	3	subglottic	subglottic	JJ
cord-017161-lcqrd4v0	298	4	polyps	polyp	NNS
cord-017161-lcqrd4v0	298	5	and/or	and/or	CC
cord-017161-lcqrd4v0	298	6	largeand	largeand	JJ
cord-017161-lcqrd4v0	298	7	medium	medium	NN
cord-017161-lcqrd4v0	298	8	-	-	HYPH
cord-017161-lcqrd4v0	298	9	sized	sized	JJ
cord-017161-lcqrd4v0	298	10	airway	airway	NN
cord-017161-lcqrd4v0	298	11	stenoses	stenosis	NNS
cord-017161-lcqrd4v0	298	12	can	can	MD
cord-017161-lcqrd4v0	298	13	result	result	VB
cord-017161-lcqrd4v0	298	14	from	from	IN
cord-017161-lcqrd4v0	298	15	granulomatous	granulomatous	JJ
cord-017161-lcqrd4v0	298	16	in	in	IN
cord-017161-lcqrd4v0	298	17	fl	fl	NNP
cord-017161-lcqrd4v0	298	18	ammation	ammation	NNP
cord-017161-lcqrd4v0	298	19	[	[	-LRB-
cord-017161-lcqrd4v0	298	20	34	34	CD
cord-017161-lcqrd4v0	298	21	]	]	-RRB-
cord-017161-lcqrd4v0	298	22	.	.	.
cord-017161-lcqrd4v0	299	1	Lower	low	JJR
cord-017161-lcqrd4v0	299	2	respiratory	respiratory	JJ
cord-017161-lcqrd4v0	299	3	tract	tract	NN
cord-017161-lcqrd4v0	299	4	manifestations	manifestation	NNS
cord-017161-lcqrd4v0	299	5	also	also	RB
cord-017161-lcqrd4v0	299	6	include	include	VBP
cord-017161-lcqrd4v0	299	7	granulomatous	granulomatous	JJ
cord-017161-lcqrd4v0	299	8	pulmonary	pulmonary	JJ
cord-017161-lcqrd4v0	299	9	nodules	nodule	NNS
cord-017161-lcqrd4v0	299	10	with	with	IN
cord-017161-lcqrd4v0	299	11	or	or	CC
cord-017161-lcqrd4v0	299	12	without	without	IN
cord-017161-lcqrd4v0	299	13	central	central	JJ
cord-017161-lcqrd4v0	299	14	cavitation	cavitation	NN
cord-017161-lcqrd4v0	299	15	and	and	CC
cord-017161-lcqrd4v0	299	16	pulmonary	pulmonary	JJ
cord-017161-lcqrd4v0	299	17	haemorrhages	haemorrhage	NNS
cord-017161-lcqrd4v0	299	18	that	that	WDT
cord-017161-lcqrd4v0	299	19	can	can	MD
cord-017161-lcqrd4v0	299	20	be	be	VB
cord-017161-lcqrd4v0	299	21	relatively	relatively	RB
cord-017161-lcqrd4v0	299	22	asymptomatic	asymptomatic	JJ
cord-017161-lcqrd4v0	299	23	but	but	CC
cord-017161-lcqrd4v0	299	24	result	result	VBP
cord-017161-lcqrd4v0	299	25	in	in	IN
cord-017161-lcqrd4v0	299	26	evanescent	evanescent	JJ
cord-017161-lcqrd4v0	299	27	pulmonary	pulmonary	JJ
cord-017161-lcqrd4v0	299	28	shadows	shadow	NNS
cord-017161-lcqrd4v0	299	29	on	on	IN
cord-017161-lcqrd4v0	299	30	chest	chest	NN
cord-017161-lcqrd4v0	299	31	X	x	NN
cord-017161-lcqrd4v0	299	32	-	-	NN
cord-017161-lcqrd4v0	299	33	ray	ray	NN
cord-017161-lcqrd4v0	299	34	,	,	,
cord-017161-lcqrd4v0	299	35	or	or	CC
cord-017161-lcqrd4v0	299	36	catastrophic	catastrophic	JJ
cord-017161-lcqrd4v0	299	37	pulmonary	pulmonary	JJ
cord-017161-lcqrd4v0	299	38	haemorrhage	haemorrhage	NN
cord-017161-lcqrd4v0	299	39	from	from	IN
cord-017161-lcqrd4v0	299	40	pulmonary	pulmonary	JJ
cord-017161-lcqrd4v0	299	41	capillaritis	capillaritis	NN
cord-017161-lcqrd4v0	299	42	associated	associate	VBN
cord-017161-lcqrd4v0	299	43	with	with	IN
cord-017161-lcqrd4v0	299	44	respiratory	respiratory	JJ
cord-017161-lcqrd4v0	299	45	failure	failure	NN
cord-017161-lcqrd4v0	299	46	and	and	CC
cord-017161-lcqrd4v0	299	47	high	high	JJ
cord-017161-lcqrd4v0	299	48	mortality	mortality	NN
cord-017161-lcqrd4v0	299	49	[	[	-LRB-
cord-017161-lcqrd4v0	299	50	34	34	CD
cord-017161-lcqrd4v0	299	51	]	]	-RRB-
cord-017161-lcqrd4v0	299	52	.	.	.
cord-017161-lcqrd4v0	300	1	The	the	DT
cord-017161-lcqrd4v0	300	2	typical	typical	JJ
cord-017161-lcqrd4v0	300	3	renal	renal	JJ
cord-017161-lcqrd4v0	300	4	lesion	lesion	NN
cord-017161-lcqrd4v0	300	5	is	be	VBZ
cord-017161-lcqrd4v0	300	6	a	a	DT
cord-017161-lcqrd4v0	300	7	focal	focal	JJ
cord-017161-lcqrd4v0	300	8	segmental	segmental	JJ
cord-017161-lcqrd4v0	300	9	necrotizing	necrotize	VBG
cord-017161-lcqrd4v0	300	10	glomerulonephritis	glomerulonephritis	NN
cord-017161-lcqrd4v0	300	11	,	,	,
cord-017161-lcqrd4v0	300	12	with	with	IN
cord-017161-lcqrd4v0	300	13	pauci	pauci	NN
cord-017161-lcqrd4v0	300	14	-	-	HYPH
cord-017161-lcqrd4v0	300	15	immune	immune	JJ
cord-017161-lcqrd4v0	300	16	crescentic	crescentic	JJ
cord-017161-lcqrd4v0	300	17	glomerular	glomerular	JJ
cord-017161-lcqrd4v0	300	18	changes	change	NNS
cord-017161-lcqrd4v0	300	19	[	[	-LRB-
cord-017161-lcqrd4v0	300	20	34	34	CD
cord-017161-lcqrd4v0	300	21	]	]	-RRB-
cord-017161-lcqrd4v0	300	22	.	.	.
cord-017161-lcqrd4v0	301	1	Clinical	clinical	JJ
cord-017161-lcqrd4v0	301	2	manifestations	manifestation	NNS
cord-017161-lcqrd4v0	301	3	include	include	VBP
cord-017161-lcqrd4v0	301	4	hypertension	hypertension	NN
cord-017161-lcqrd4v0	301	5	,	,	,
cord-017161-lcqrd4v0	301	6	signi	signi	NNP
cord-017161-lcqrd4v0	301	7	fi	fi	NNP
cord-017161-lcqrd4v0	301	8	ca	can	MD
cord-017161-lcqrd4v0	301	9	nt	not	RB
cord-017161-lcqrd4v0	301	10	proteinuria	proteinuria	VB
cord-017161-lcqrd4v0	301	11	,	,	,
cord-017161-lcqrd4v0	301	12	nephritic	nephritic	JJ
cord-017161-lcqrd4v0	301	13	and	and	CC
cord-017161-lcqrd4v0	301	14	nephrotic	nephrotic	JJ
cord-017161-lcqrd4v0	301	15	syndrome	syndrome	NN
cord-017161-lcqrd4v0	301	16	,	,	,
cord-017161-lcqrd4v0	301	17	and	and	CC
cord-017161-lcqrd4v0	301	18	ultimately	ultimately	RB
cord-017161-lcqrd4v0	301	19	the	the	DT
cord-017161-lcqrd4v0	301	20	protean	protean	JJ
cord-017161-lcqrd4v0	301	21	clinical	clinical	JJ
cord-017161-lcqrd4v0	301	22	features	feature	VBZ
cord-017161-lcqrd4v0	301	23	renal	renal	JJ
cord-017161-lcqrd4v0	301	24	failure	failure	NN
cord-017161-lcqrd4v0	301	25	[	[	-LRB-
cord-017161-lcqrd4v0	301	26	34	34	CD
cord-017161-lcqrd4v0	301	27	]	]	-RRB-
cord-017161-lcqrd4v0	301	28	.	.	.
cord-017161-lcqrd4v0	302	1	Other	other	JJ
cord-017161-lcqrd4v0	302	2	manifestations	manifestation	NNS
cord-017161-lcqrd4v0	302	3	include	include	VBP
cord-017161-lcqrd4v0	302	4	orbital	orbital	JJ
cord-017161-lcqrd4v0	302	5	involvement	involvement	NN
cord-017161-lcqrd4v0	302	6	with	with	IN
cord-017161-lcqrd4v0	302	7	granuloma	granuloma	NN
cord-017161-lcqrd4v0	302	8	,	,	,
cord-017161-lcqrd4v0	302	9	retinal	retinal	JJ
cord-017161-lcqrd4v0	302	10	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	302	11	,	,	,
cord-017161-lcqrd4v0	302	12	peripheral	peripheral	JJ
cord-017161-lcqrd4v0	302	13	gangrene	gangrene	NN
cord-017161-lcqrd4v0	302	14	with	with	IN
cord-017161-lcqrd4v0	302	15	tissue	tissue	NN
cord-017161-lcqrd4v0	302	16	loss	loss	NN
cord-017161-lcqrd4v0	302	17	,	,	,
cord-017161-lcqrd4v0	302	18	and	and	CC
cord-017161-lcqrd4v0	302	19	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	302	20	of	of	IN
cord-017161-lcqrd4v0	302	21	the	the	DT
cord-017161-lcqrd4v0	302	22	skin	skin	NN
cord-017161-lcqrd4v0	302	23	,	,	,
cord-017161-lcqrd4v0	302	24	gut	gut	NN
cord-017161-lcqrd4v0	302	25	,	,	,
cord-017161-lcqrd4v0	302	26	heart	heart	NN
cord-017161-lcqrd4v0	302	27	,	,	,
cord-017161-lcqrd4v0	302	28	central	central	JJ
cord-017161-lcqrd4v0	302	29	nervous	nervous	JJ
cord-017161-lcqrd4v0	302	30	system	system	NN
cord-017161-lcqrd4v0	302	31	and/or	and/or	CC
cord-017161-lcqrd4v0	302	32	peripheral	peripheral	JJ
cord-017161-lcqrd4v0	302	33	nerves	nerve	NNS
cord-017161-lcqrd4v0	302	34	(	(	-LRB-
cord-017161-lcqrd4v0	302	35	mononeuritis	mononeuritis	NNP
cord-017161-lcqrd4v0	302	36	multiplex	multiplex	NNP
cord-017161-lcqrd4v0	302	37	)	)	-RRB-
cord-017161-lcqrd4v0	302	38	,	,	,
cord-017161-lcqrd4v0	302	39	salivary	salivary	JJ
cord-017161-lcqrd4v0	302	40	glands	gland	NNS
cord-017161-lcqrd4v0	302	41	,	,	,
cord-017161-lcqrd4v0	302	42	gonads	gonad	NNS
cord-017161-lcqrd4v0	302	43	and	and	CC
cord-017161-lcqrd4v0	302	44	breast	breast	NN
cord-017161-lcqrd4v0	302	45	[	[	-LRB-
cord-017161-lcqrd4v0	302	46	34	34	CD
cord-017161-lcqrd4v0	302	47	]	]	-RRB-
cord-017161-lcqrd4v0	302	48	.	.	.
cord-017161-lcqrd4v0	303	1	Non	non	JJ
cord-017161-lcqrd4v0	303	2	-	-	JJ
cord-017161-lcqrd4v0	303	3	speci	speci	JJ
cord-017161-lcqrd4v0	303	4	fi	fi	NN
cord-017161-lcqrd4v0	303	5	c	c	NN
cord-017161-lcqrd4v0	303	6	symptoms	symptom	NNS
cord-017161-lcqrd4v0	303	7	such	such	JJ
cord-017161-lcqrd4v0	303	8	as	as	IN
cord-017161-lcqrd4v0	303	9	malaise	malaise	NN
cord-017161-lcqrd4v0	303	10	,	,	,
cord-017161-lcqrd4v0	303	11	fever	fever	NN
cord-017161-lcqrd4v0	303	12	,	,	,
cord-017161-lcqrd4v0	303	13	weight	weight	NN
cord-017161-lcqrd4v0	303	14	loss	loss	NN
cord-017161-lcqrd4v0	303	15	or	or	CC
cord-017161-lcqrd4v0	303	16	growth	growth	NN
cord-017161-lcqrd4v0	303	17	failure	failure	NN
cord-017161-lcqrd4v0	303	18	,	,	,
cord-017161-lcqrd4v0	303	19	arthralgia	arthralgia	NN
cord-017161-lcqrd4v0	303	20	and	and	CC
cord-017161-lcqrd4v0	303	21	arthritis	arthritis	NN
cord-017161-lcqrd4v0	303	22	are	be	VBP
cord-017161-lcqrd4v0	303	23	relatively	relatively	RB
cord-017161-lcqrd4v0	303	24	common	common	JJ
cord-017161-lcqrd4v0	303	25	[	[	-LRB-
cord-017161-lcqrd4v0	303	26	34	34	CD
cord-017161-lcqrd4v0	303	27	]	]	-RRB-
cord-017161-lcqrd4v0	303	28	.	.	.
cord-017161-lcqrd4v0	304	1	Renal	renal	JJ
cord-017161-lcqrd4v0	304	2	morbidity	morbidity	NN
cord-017161-lcqrd4v0	304	3	and	and	CC
cord-017161-lcqrd4v0	304	4	mortality	mortality	NN
cord-017161-lcqrd4v0	304	5	is	be	VBZ
cord-017161-lcqrd4v0	304	6	a	a	DT
cord-017161-lcqrd4v0	304	7	major	major	JJ
cord-017161-lcqrd4v0	304	8	concern	concern	NN
cord-017161-lcqrd4v0	304	9	in	in	IN
cord-017161-lcqrd4v0	304	10	the	the	DT
cord-017161-lcqrd4v0	304	11	AAV	AAV	NNP
cord-017161-lcqrd4v0	304	12	,	,	,
cord-017161-lcqrd4v0	304	13	hence	hence	RB
cord-017161-lcqrd4v0	304	14	therapy	therapy	NN
cord-017161-lcqrd4v0	304	15	aimed	aim	VBN
cord-017161-lcqrd4v0	304	16	at	at	IN
cord-017161-lcqrd4v0	304	17	preservation	preservation	NN
cord-017161-lcqrd4v0	304	18	of	of	IN
cord-017161-lcqrd4v0	304	19	renal	renal	JJ
cord-017161-lcqrd4v0	304	20	function	function	NN
cord-017161-lcqrd4v0	304	21	is	be	VBZ
cord-017161-lcqrd4v0	304	22	a	a	DT
cord-017161-lcqrd4v0	304	23	recurring	recur	VBG
cord-017161-lcqrd4v0	304	24	theme	theme	NN
cord-017161-lcqrd4v0	304	25	for	for	IN
cord-017161-lcqrd4v0	304	26	the	the	DT
cord-017161-lcqrd4v0	304	27	treatment	treatment	NN
cord-017161-lcqrd4v0	304	28	of	of	IN
cord-017161-lcqrd4v0	304	29	AAV	AAV	NNP
cord-017161-lcqrd4v0	304	30	in	in	IN
cord-017161-lcqrd4v0	304	31	adults	adult	NNS
cord-017161-lcqrd4v0	304	32	and	and	CC
cord-017161-lcqrd4v0	304	33	children	child	NNS
cord-017161-lcqrd4v0	304	34	[	[	-LRB-
cord-017161-lcqrd4v0	304	35	174	174	CD
cord-017161-lcqrd4v0	304	36	]	]	-RRB-
cord-017161-lcqrd4v0	304	37	.	.	.
cord-017161-lcqrd4v0	305	1	Treatment	treatment	NN
cord-017161-lcqrd4v0	305	2	for	for	IN
cord-017161-lcqrd4v0	305	3	paediatric	paediatric	JJ
cord-017161-lcqrd4v0	305	4	AAV	AAV	NNP
cord-017161-lcqrd4v0	305	5	is	be	VBZ
cord-017161-lcqrd4v0	305	6	broadly	broadly	RB
cord-017161-lcqrd4v0	305	7	similar	similar	JJ
cord-017161-lcqrd4v0	305	8	to	to	IN
cord-017161-lcqrd4v0	305	9	the	the	DT
cord-017161-lcqrd4v0	305	10	approach	approach	NN
cord-017161-lcqrd4v0	305	11	in	in	IN
cord-017161-lcqrd4v0	305	12	adults	adult	NNS
cord-017161-lcqrd4v0	305	13	,	,	,
cord-017161-lcqrd4v0	305	14	with	with	IN
cord-017161-lcqrd4v0	305	15	corticosteroids	corticosteroid	NNS
cord-017161-lcqrd4v0	305	16	,	,	,
cord-017161-lcqrd4v0	305	17	cyclophosphamide	cyclophosphamide	FW
cord-017161-lcqrd4v0	305	18	(	(	-LRB-
cord-017161-lcqrd4v0	305	19	usually	usually	RB
cord-017161-lcqrd4v0	305	20	6	6	CD
cord-017161-lcqrd4v0	305	21	-	-	SYM
cord-017161-lcqrd4v0	305	22	10	10	CD
cord-017161-lcqrd4v0	305	23	intravenous	intravenous	JJ
cord-017161-lcqrd4v0	305	24	doses	dose	NNS
cord-017161-lcqrd4v0	305	25	at	at	IN
cord-017161-lcqrd4v0	305	26	500	500	CD
cord-017161-lcqrd4v0	305	27	-	-	SYM
cord-017161-lcqrd4v0	305	28	1,000	1,000	CD
cord-017161-lcqrd4v0	305	29	mg	mg	NNP
cord-017161-lcqrd4v0	305	30	/	/	SYM
cord-017161-lcqrd4v0	305	31	m	m	NN
cord-017161-lcqrd4v0	305	32	2	2	CD
cord-017161-lcqrd4v0	305	33	[	[	-LRB-
cord-017161-lcqrd4v0	305	34	2	2	CD
cord-017161-lcqrd4v0	305	35	]	]	-RRB-
cord-017161-lcqrd4v0	305	36	per	per	IN
cord-017161-lcqrd4v0	305	37	dose	dose	NN
cord-017161-lcqrd4v0	305	38	given	give	VBN
cord-017161-lcqrd4v0	305	39	3	3	CD
cord-017161-lcqrd4v0	305	40	-	-	SYM
cord-017161-lcqrd4v0	305	41	4	4	CD
cord-017161-lcqrd4v0	305	42	weekly	weekly	NN
cord-017161-lcqrd4v0	305	43	;	;	:
cord-017161-lcqrd4v0	305	44	alternatively	alternatively	RB
cord-017161-lcqrd4v0	305	45	given	give	VBN
cord-017161-lcqrd4v0	305	46	orally	orally	RB
cord-017161-lcqrd4v0	305	47	at	at	IN
cord-017161-lcqrd4v0	305	48	2	2	CD
cord-017161-lcqrd4v0	305	49	mg	mg	NNP
cord-017161-lcqrd4v0	305	50	/	/	SYM
cord-017161-lcqrd4v0	305	51	kg	kg	NNP
cord-017161-lcqrd4v0	305	52	/	/	SYM
cord-017161-lcqrd4v0	305	53	day	day	NN
cord-017161-lcqrd4v0	305	54	for	for	IN
cord-017161-lcqrd4v0	305	55	2	2	CD
cord-017161-lcqrd4v0	305	56	-	-	SYM
cord-017161-lcqrd4v0	305	57	3	3	CD
cord-017161-lcqrd4v0	305	58	months	month	NNS
cord-017161-lcqrd4v0	305	59	)	)	-RRB-
cord-017161-lcqrd4v0	305	60	,	,	,
cord-017161-lcqrd4v0	305	61	plasma	plasma	NN
cord-017161-lcqrd4v0	305	62	exchange	exchange	NN
cord-017161-lcqrd4v0	305	63	(	(	-LRB-
cord-017161-lcqrd4v0	305	64	particularly	particularly	RB
cord-017161-lcqrd4v0	305	65	for	for	IN
cord-017161-lcqrd4v0	305	66	pulmonary	pulmonary	JJ
cord-017161-lcqrd4v0	305	67	capillaritis	capillaritis	NN
cord-017161-lcqrd4v0	305	68	and/or	and/or	CC
cord-017161-lcqrd4v0	305	69	rapidly	rapidly	RB
cord-017161-lcqrd4v0	305	70	progressive	progressive	JJ
cord-017161-lcqrd4v0	305	71	glomerulonephritis-"pulmonary	glomerulonephritis-"pulmonary	JJ
cord-017161-lcqrd4v0	305	72	-	-	HYPH
cord-017161-lcqrd4v0	305	73	renal	renal	JJ
cord-017161-lcqrd4v0	305	74	syndrome	syndrome	NN
cord-017161-lcqrd4v0	305	75	"	"	''
cord-017161-lcqrd4v0	305	76	)	)	-RRB-
cord-017161-lcqrd4v0	305	77	routinely	routinely	RB
cord-017161-lcqrd4v0	305	78	employed	employ	VBN
cord-017161-lcqrd4v0	305	79	to	to	TO
cord-017161-lcqrd4v0	305	80	induce	induce	VB
cord-017161-lcqrd4v0	305	81	remission	remission	NN
cord-017161-lcqrd4v0	305	82	[	[	-LRB-
cord-017161-lcqrd4v0	305	83	3	3	CD
cord-017161-lcqrd4v0	305	84	,	,	,
cord-017161-lcqrd4v0	305	85	175	175	CD
cord-017161-lcqrd4v0	305	86	]	]	-RRB-
cord-017161-lcqrd4v0	305	87	.	.	.
cord-017161-lcqrd4v0	306	1	Intravenous	intravenous	NN
cord-017161-lcqrd4v0	306	2	pulsed	pulse	VBN
cord-017161-lcqrd4v0	306	3	cyclophosphamide	cyclophosphamide	RB
cord-017161-lcqrd4v0	306	4	is	be	VBZ
cord-017161-lcqrd4v0	306	5	increasingly	increasingly	RB
cord-017161-lcqrd4v0	306	6	favoured	favour	VBN
cord-017161-lcqrd4v0	306	7	over	over	IN
cord-017161-lcqrd4v0	306	8	oral	oral	JJ
cord-017161-lcqrd4v0	306	9	continuous	continuous	JJ
cord-017161-lcqrd4v0	306	10	cyclophosphamide	cyclophosphamide	NN
cord-017161-lcqrd4v0	306	11	in	in	IN
cord-017161-lcqrd4v0	306	12	adults	adult	NNS
cord-017161-lcqrd4v0	306	13	because	because	IN
cord-017161-lcqrd4v0	306	14	of	of	IN
cord-017161-lcqrd4v0	306	15	reduced	reduce	VBN
cord-017161-lcqrd4v0	306	16	cumulative	cumulative	JJ
cord-017161-lcqrd4v0	306	17	dose	dose	NN
cord-017161-lcqrd4v0	306	18	and	and	CC
cord-017161-lcqrd4v0	306	19	less	less	RBR
cord-017161-lcqrd4v0	306	20	neutropenic	neutropenic	JJ
cord-017161-lcqrd4v0	306	21	sepsis	sepsis	NN
cord-017161-lcqrd4v0	306	22	[	[	-LRB-
cord-017161-lcqrd4v0	306	23	176	176	CD
cord-017161-lcqrd4v0	306	24	,	,	,
cord-017161-lcqrd4v0	306	25	177	177	CD
cord-017161-lcqrd4v0	306	26	]	]	-RRB-
cord-017161-lcqrd4v0	306	27	and	and	CC
cord-017161-lcqrd4v0	306	28	is	be	VBZ
cord-017161-lcqrd4v0	306	29	thus	thus	RB
cord-017161-lcqrd4v0	306	30	increasingly	increasingly	RB
cord-017161-lcqrd4v0	306	31	used	use	VBN
cord-017161-lcqrd4v0	306	32	to	to	TO
cord-017161-lcqrd4v0	306	33	treat	treat	VB
cord-017161-lcqrd4v0	306	34	children	child	NNS
cord-017161-lcqrd4v0	306	35	with	with	IN
cord-017161-lcqrd4v0	306	36	AAV	AAV	NNP
cord-017161-lcqrd4v0	306	37	as	as	RB
cord-017161-lcqrd4v0	306	38	well	well	RB
cord-017161-lcqrd4v0	306	39	,	,	,
cord-017161-lcqrd4v0	306	40	albeit	albeit	IN
cord-017161-lcqrd4v0	306	41	without	without	IN
cord-017161-lcqrd4v0	306	42	good	good	JJ
cord-017161-lcqrd4v0	306	43	paediatric	paediatric	JJ
cord-017161-lcqrd4v0	306	44	evidence	evidence	NN
cord-017161-lcqrd4v0	306	45	.	.	.
cord-017161-lcqrd4v0	307	1	This	this	DT
cord-017161-lcqrd4v0	307	2	is	be	VBZ
cord-017161-lcqrd4v0	307	3	followed	follow	VBN
cord-017161-lcqrd4v0	307	4	by	by	IN
cord-017161-lcqrd4v0	307	5	low	low	JJ
cord-017161-lcqrd4v0	307	6	-	-	HYPH
cord-017161-lcqrd4v0	307	7	dose	dose	NN
cord-017161-lcqrd4v0	307	8	corticosteroids	corticosteroid	NNS
cord-017161-lcqrd4v0	307	9	and	and	CC
cord-017161-lcqrd4v0	307	10	azathioprine	azathioprine	NN
cord-017161-lcqrd4v0	307	11	(	(	-LRB-
cord-017161-lcqrd4v0	307	12	1.5	1.5	CD
cord-017161-lcqrd4v0	307	13	-	-	SYM
cord-017161-lcqrd4v0	307	14	3	3	CD
cord-017161-lcqrd4v0	307	15	mg	mg	NNP
cord-017161-lcqrd4v0	307	16	/	/	SYM
cord-017161-lcqrd4v0	307	17	kg	kg	NNP
cord-017161-lcqrd4v0	307	18	/	/	SYM
cord-017161-lcqrd4v0	307	19	day	day	NN
cord-017161-lcqrd4v0	307	20	)	)	-RRB-
cord-017161-lcqrd4v0	307	21	to	to	TO
cord-017161-lcqrd4v0	307	22	maintain	maintain	VB
cord-017161-lcqrd4v0	307	23	remission	remission	NN
cord-017161-lcqrd4v0	307	24	[	[	-LRB-
cord-017161-lcqrd4v0	307	25	3	3	CD
cord-017161-lcqrd4v0	307	26	,	,	,
cord-017161-lcqrd4v0	307	27	178	178	CD
cord-017161-lcqrd4v0	307	28	]	]	-RRB-
cord-017161-lcqrd4v0	307	29	.	.	.
cord-017161-lcqrd4v0	308	1	Anti	anti	JJ
cord-017161-lcqrd4v0	308	2	-	-	JJ
cord-017161-lcqrd4v0	308	3	platelet	platelet	JJ
cord-017161-lcqrd4v0	308	4	doses	dose	NNS
cord-017161-lcqrd4v0	308	5	of	of	IN
cord-017161-lcqrd4v0	308	6	aspirin	aspirin	NN
cord-017161-lcqrd4v0	308	7	(	(	-LRB-
cord-017161-lcqrd4v0	308	8	1	1	CD
cord-017161-lcqrd4v0	308	9	-	-	SYM
cord-017161-lcqrd4v0	308	10	5	5	CD
cord-017161-lcqrd4v0	308	11	mg	mg	NNP
cord-017161-lcqrd4v0	308	12	/	/	SYM
cord-017161-lcqrd4v0	308	13	kg	kg	NNP
cord-017161-lcqrd4v0	308	14	/	/	SYM
cord-017161-lcqrd4v0	308	15	day	day	NN
cord-017161-lcqrd4v0	308	16	)	)	-RRB-
cord-017161-lcqrd4v0	308	17	are	be	VBP
cord-017161-lcqrd4v0	308	18	empirically	empirically	RB
cord-017161-lcqrd4v0	308	19	employed	employ	VBN
cord-017161-lcqrd4v0	308	20	on	on	IN
cord-017161-lcqrd4v0	308	21	the	the	DT
cord-017161-lcqrd4v0	308	22	basis	basis	NN
cord-017161-lcqrd4v0	308	23	of	of	IN
cord-017161-lcqrd4v0	308	24	the	the	DT
cord-017161-lcqrd4v0	308	25	increased	increase	VBN
cord-017161-lcqrd4v0	308	26	risk	risk	NN
cord-017161-lcqrd4v0	308	27	of	of	IN
cord-017161-lcqrd4v0	308	28	thrombosis	thrombosis	NN
cord-017161-lcqrd4v0	308	29	associated	associate	VBN
cord-017161-lcqrd4v0	308	30	with	with	IN
cord-017161-lcqrd4v0	308	31	the	the	DT
cord-017161-lcqrd4v0	308	32	disease	disease	NN
cord-017161-lcqrd4v0	308	33	process	process	NN
cord-017161-lcqrd4v0	308	34	[	[	-LRB-
cord-017161-lcqrd4v0	308	35	179	179	CD
cord-017161-lcqrd4v0	308	36	]	]	-RRB-
cord-017161-lcqrd4v0	308	37	.	.	.
cord-017161-lcqrd4v0	309	1	Methotrexate	Methotrexate	NNP
cord-017161-lcqrd4v0	309	2	may	may	MD
cord-017161-lcqrd4v0	309	3	have	have	VB
cord-017161-lcqrd4v0	309	4	a	a	DT
cord-017161-lcqrd4v0	309	5	role	role	NN
cord-017161-lcqrd4v0	309	6	for	for	IN
cord-017161-lcqrd4v0	309	7	induction	induction	NN
cord-017161-lcqrd4v0	309	8	of	of	IN
cord-017161-lcqrd4v0	309	9	remission	remission	NN
cord-017161-lcqrd4v0	309	10	in	in	IN
cord-017161-lcqrd4v0	309	11	patients	patient	NNS
cord-017161-lcqrd4v0	309	12	with	with	IN
cord-017161-lcqrd4v0	309	13	limited	limited	JJ
cord-017161-lcqrd4v0	309	14	WG	WG	NNP
cord-017161-lcqrd4v0	309	15	[	[	-LRB-
cord-017161-lcqrd4v0	309	16	180	180	CD
cord-017161-lcqrd4v0	309	17	]	]	-RRB-
cord-017161-lcqrd4v0	309	18	,	,	,
cord-017161-lcqrd4v0	309	19	but	but	CC
cord-017161-lcqrd4v0	309	20	is	be	VBZ
cord-017161-lcqrd4v0	309	21	less	less	RBR
cord-017161-lcqrd4v0	309	22	commonly	commonly	RB
cord-017161-lcqrd4v0	309	23	used	use	VBN
cord-017161-lcqrd4v0	309	24	as	as	IN
cord-017161-lcqrd4v0	309	25	an	an	DT
cord-017161-lcqrd4v0	309	26	induction	induction	NN
cord-017161-lcqrd4v0	309	27	agent	agent	NN
cord-017161-lcqrd4v0	309	28	in	in	IN
cord-017161-lcqrd4v0	309	29	children	child	NNS
cord-017161-lcqrd4v0	309	30	with	with	IN
cord-017161-lcqrd4v0	309	31	AAV	AAV	NNP
cord-017161-lcqrd4v0	309	32	.	.	.
cord-017161-lcqrd4v0	310	1	Co	Co	NNP
cord-017161-lcqrd4v0	310	2	-	-	NNP
cord-017161-lcqrd4v0	310	3	trimoxazole	trimoxazole	NNP
cord-017161-lcqrd4v0	310	4	is	be	VBZ
cord-017161-lcqrd4v0	310	5	commonly	commonly	RB
cord-017161-lcqrd4v0	310	6	added	add	VBN
cord-017161-lcqrd4v0	310	7	for	for	IN
cord-017161-lcqrd4v0	310	8	the	the	DT
cord-017161-lcqrd4v0	310	9	treatment	treatment	NN
cord-017161-lcqrd4v0	310	10	of	of	IN
cord-017161-lcqrd4v0	310	11	WG	WG	NNP
cord-017161-lcqrd4v0	310	12	,	,	,
cord-017161-lcqrd4v0	310	13	particularly	particularly	RB
cord-017161-lcqrd4v0	310	14	in	in	IN
cord-017161-lcqrd4v0	310	15	those	those	DT
cord-017161-lcqrd4v0	310	16	with	with	IN
cord-017161-lcqrd4v0	310	17	upper	upper	JJ
cord-017161-lcqrd4v0	310	18	respiratory	respiratory	JJ
cord-017161-lcqrd4v0	310	19	tract	tract	NN
cord-017161-lcqrd4v0	310	20	involvement	involvement	NN
cord-017161-lcqrd4v0	310	21	,	,	,
cord-017161-lcqrd4v0	310	22	serving	serve	VBG
cord-017161-lcqrd4v0	310	23	both	both	CC
cord-017161-lcqrd4v0	310	24	as	as	IN
cord-017161-lcqrd4v0	310	25	prophylaxis	prophylaxis	NN
cord-017161-lcqrd4v0	310	26	against	against	IN
cord-017161-lcqrd4v0	310	27	opportunistic	opportunistic	JJ
cord-017161-lcqrd4v0	310	28	infection	infection	NN
cord-017161-lcqrd4v0	310	29	and	and	CC
cord-017161-lcqrd4v0	310	30	as	as	IN
cord-017161-lcqrd4v0	310	31	a	a	DT
cord-017161-lcqrd4v0	310	32	possible	possible	JJ
cord-017161-lcqrd4v0	310	33	disease	disease	NN
cord-017161-lcqrd4v0	310	34	-	-	HYPH
cord-017161-lcqrd4v0	310	35	modifying	modify	VBG
cord-017161-lcqrd4v0	310	36	agent	agent	NN
cord-017161-lcqrd4v0	310	37	[	[	-LRB-
cord-017161-lcqrd4v0	310	38	139	139	CD
cord-017161-lcqrd4v0	310	39	]	]	-RRB-
cord-017161-lcqrd4v0	310	40	.	.	.
cord-017161-lcqrd4v0	311	1	Recommendations	recommendation	NNS
cord-017161-lcqrd4v0	311	2	regarding	regard	VBG
cord-017161-lcqrd4v0	311	3	duration	duration	NN
cord-017161-lcqrd4v0	311	4	of	of	IN
cord-017161-lcqrd4v0	311	5	maintenance	maintenance	NN
cord-017161-lcqrd4v0	311	6	therapy	therapy	NN
cord-017161-lcqrd4v0	311	7	are	be	VBP
cord-017161-lcqrd4v0	311	8	based	base	VBN
cord-017161-lcqrd4v0	311	9	on	on	IN
cord-017161-lcqrd4v0	311	10	adult	adult	NN
cord-017161-lcqrd4v0	311	11	trial	trial	NN
cord-017161-lcqrd4v0	311	12	data	datum	NNS
cord-017161-lcqrd4v0	311	13	,	,	,
cord-017161-lcqrd4v0	311	14	suggesting	suggest	VBG
cord-017161-lcqrd4v0	311	15	that	that	IN
cord-017161-lcqrd4v0	311	16	the	the	DT
cord-017161-lcqrd4v0	311	17	strongest	strong	JJS
cord-017161-lcqrd4v0	311	18	predictor	predictor	NN
cord-017161-lcqrd4v0	311	19	of	of	IN
cord-017161-lcqrd4v0	311	20	relapse	relapse	NN
cord-017161-lcqrd4v0	311	21	is	be	VBZ
cord-017161-lcqrd4v0	311	22	withdrawal	withdrawal	NN
cord-017161-lcqrd4v0	311	23	of	of	IN
cord-017161-lcqrd4v0	311	24	therapy	therapy	NN
cord-017161-lcqrd4v0	311	25	,	,	,
cord-017161-lcqrd4v0	311	26	and	and	CC
cord-017161-lcqrd4v0	311	27	hence	hence	RB
cord-017161-lcqrd4v0	311	28	maintenance	maintenance	NN
cord-017161-lcqrd4v0	311	29	therapy	therapy	NN
cord-017161-lcqrd4v0	311	30	should	should	MD
cord-017161-lcqrd4v0	311	31	be	be	VB
cord-017161-lcqrd4v0	311	32	continued	continue	VBN
cord-017161-lcqrd4v0	311	33	for	for	IN
cord-017161-lcqrd4v0	311	34	several	several	JJ
cord-017161-lcqrd4v0	311	35	years	year	NNS
cord-017161-lcqrd4v0	311	36	[	[	-LRB-
cord-017161-lcqrd4v0	311	37	174	174	CD
cord-017161-lcqrd4v0	311	38	]	]	-RRB-
cord-017161-lcqrd4v0	311	39	.	.	.
cord-017161-lcqrd4v0	312	1	As	as	IN
cord-017161-lcqrd4v0	312	2	a	a	DT
cord-017161-lcqrd4v0	312	3	general	general	JJ
cord-017161-lcqrd4v0	312	4	therapeutic	therapeutic	JJ
cord-017161-lcqrd4v0	312	5	measure	measure	NN
cord-017161-lcqrd4v0	312	6	,	,	,
cord-017161-lcqrd4v0	312	7	prophylaxis	prophylaxis	NN
cord-017161-lcqrd4v0	312	8	against	against	IN
cord-017161-lcqrd4v0	312	9	osteoporosis	osteoporosis	NN
cord-017161-lcqrd4v0	312	10	,	,	,
cord-017161-lcqrd4v0	312	11	gastrointestinal	gastrointestinal	JJ
cord-017161-lcqrd4v0	312	12	ulceration	ulceration	NN
cord-017161-lcqrd4v0	312	13	and	and	CC
cord-017161-lcqrd4v0	312	14	infection	infection	NN
cord-017161-lcqrd4v0	312	15	(	(	-LRB-
cord-017161-lcqrd4v0	312	16	bacterial	bacterial	JJ
cord-017161-lcqrd4v0	312	17	,	,	,
cord-017161-lcqrd4v0	312	18	protozoal	protozoal	NN
cord-017161-lcqrd4v0	312	19	and	and	CC
cord-017161-lcqrd4v0	312	20	fungal	fungal	NN
cord-017161-lcqrd4v0	312	21	)	)	-RRB-
cord-017161-lcqrd4v0	312	22	is	be	VBZ
cord-017161-lcqrd4v0	312	23	standard	standard	JJ
cord-017161-lcqrd4v0	312	24	for	for	IN
cord-017161-lcqrd4v0	312	25	treatment	treatment	NN
cord-017161-lcqrd4v0	312	26	for	for	IN
cord-017161-lcqrd4v0	312	27	AAV	AAV	NNP
cord-017161-lcqrd4v0	312	28	[	[	-LRB-
cord-017161-lcqrd4v0	312	29	174	174	CD
cord-017161-lcqrd4v0	312	30	]	]	-RRB-
cord-017161-lcqrd4v0	312	31	.	.	.
cord-017161-lcqrd4v0	313	1	As	as	IN
cord-017161-lcqrd4v0	313	2	the	the	DT
cord-017161-lcqrd4v0	313	3	use	use	NN
cord-017161-lcqrd4v0	313	4	of	of	IN
cord-017161-lcqrd4v0	313	5	cyclophosphamide	cyclophosphamide	NN
cord-017161-lcqrd4v0	313	6	contributes	contribute	VBZ
cord-017161-lcqrd4v0	313	7	to	to	IN
cord-017161-lcqrd4v0	313	8	morbidity	morbidity	NN
cord-017161-lcqrd4v0	313	9	and	and	CC
cord-017161-lcqrd4v0	313	10	mortality	mortality	NN
cord-017161-lcqrd4v0	313	11	[	[	-LRB-
cord-017161-lcqrd4v0	313	12	3	3	CD
cord-017161-lcqrd4v0	313	13	,	,	,
cord-017161-lcqrd4v0	313	14	174	174	CD
cord-017161-lcqrd4v0	313	15	]	]	-RRB-
cord-017161-lcqrd4v0	313	16	with	with	IN
cord-017161-lcqrd4v0	313	17	infection	infection	NN
cord-017161-lcqrd4v0	313	18	playing	play	VBG
cord-017161-lcqrd4v0	313	19	a	a	DT
cord-017161-lcqrd4v0	313	20	prominent	prominent	JJ
cord-017161-lcqrd4v0	313	21	role	role	NN
cord-017161-lcqrd4v0	313	22	[	[	-LRB-
cord-017161-lcqrd4v0	313	23	181	181	CD
cord-017161-lcqrd4v0	313	24	]	]	-RRB-
cord-017161-lcqrd4v0	313	25	,	,	,
cord-017161-lcqrd4v0	313	26	and	and	CC
cord-017161-lcqrd4v0	313	27	disease	disease	NN
cord-017161-lcqrd4v0	313	28	relapses	relapse	NNS
cord-017161-lcqrd4v0	313	29	occur	occur	VBP
cord-017161-lcqrd4v0	313	30	in	in	IN
cord-017161-lcqrd4v0	313	31	50	50	CD
cord-017161-lcqrd4v0	313	32	%	%	NN
cord-017161-lcqrd4v0	313	33	of	of	IN
cord-017161-lcqrd4v0	313	34	the	the	DT
cord-017161-lcqrd4v0	313	35	patients	patient	NNS
cord-017161-lcqrd4v0	313	36	with	with	IN
cord-017161-lcqrd4v0	313	37	AAV	AAV	NNP
cord-017161-lcqrd4v0	313	38	as	as	IN
cord-017161-lcqrd4v0	313	39	drugs	drug	NNS
cord-017161-lcqrd4v0	313	40	are	be	VBP
cord-017161-lcqrd4v0	313	41	reduced	reduce	VBN
cord-017161-lcqrd4v0	313	42	or	or	CC
cord-017161-lcqrd4v0	313	43	withdrawn	withdraw	VBN
cord-017161-lcqrd4v0	313	44	,	,	,
cord-017161-lcqrd4v0	313	45	newer	new	JJR
cord-017161-lcqrd4v0	313	46	immunosuppressive	immunosuppressive	JJ
cord-017161-lcqrd4v0	313	47	agents	agent	NNS
cord-017161-lcqrd4v0	313	48	and	and	CC
cord-017161-lcqrd4v0	313	49	immunomodulatory	immunomodulatory	JJ
cord-017161-lcqrd4v0	313	50	strategies	strategy	NNS
cord-017161-lcqrd4v0	313	51	are	be	VBP
cord-017161-lcqrd4v0	313	52	being	be	VBG
cord-017161-lcqrd4v0	313	53	explored	explore	VBN
cord-017161-lcqrd4v0	313	54	in	in	IN
cord-017161-lcqrd4v0	313	55	both	both	DT
cord-017161-lcqrd4v0	313	56	adults	adult	NNS
cord-017161-lcqrd4v0	313	57	and	and	CC
cord-017161-lcqrd4v0	313	58	children	child	NNS
cord-017161-lcqrd4v0	313	59	[	[	-LRB-
cord-017161-lcqrd4v0	313	60	3	3	CD
cord-017161-lcqrd4v0	313	61	,	,	,
cord-017161-lcqrd4v0	313	62	174	174	CD
cord-017161-lcqrd4v0	313	63	]	]	-RRB-
cord-017161-lcqrd4v0	313	64	.	.	.
cord-017161-lcqrd4v0	314	1	Such	such	JJ
cord-017161-lcqrd4v0	314	2	treatments	treatment	NNS
cord-017161-lcqrd4v0	314	3	include	include	VBP
cord-017161-lcqrd4v0	314	4	MMF	mmf	NN
cord-017161-lcqrd4v0	314	5	and	and	CC
cord-017161-lcqrd4v0	314	6	rituximab	rituximab	NN
cord-017161-lcqrd4v0	314	7	,	,	,
cord-017161-lcqrd4v0	314	8	which	which	WDT
cord-017161-lcqrd4v0	314	9	have	have	VBP
cord-017161-lcqrd4v0	314	10	already	already	RB
cord-017161-lcqrd4v0	314	11	been	be	VBN
cord-017161-lcqrd4v0	314	12	reported	report	VBN
cord-017161-lcqrd4v0	314	13	to	to	TO
cord-017161-lcqrd4v0	314	14	be	be	VB
cord-017161-lcqrd4v0	314	15	effective	effective	JJ
cord-017161-lcqrd4v0	314	16	at	at	IN
cord-017161-lcqrd4v0	314	17	inducing	induce	VBG
cord-017161-lcqrd4v0	314	18	or	or	CC
cord-017161-lcqrd4v0	314	19	maintaining	maintain	VBG
cord-017161-lcqrd4v0	314	20	remission	remission	NN
cord-017161-lcqrd4v0	314	21	in	in	IN
cord-017161-lcqrd4v0	314	22	adults	adult	NNS
cord-017161-lcqrd4v0	314	23	with	with	IN
cord-017161-lcqrd4v0	314	24	AAV	AAV	NNP
cord-017161-lcqrd4v0	314	25	[	[	-LRB-
cord-017161-lcqrd4v0	314	26	182	182	CD
cord-017161-lcqrd4v0	314	27	,	,	,
cord-017161-lcqrd4v0	314	28	183	183	CD
cord-017161-lcqrd4v0	314	29	]	]	-RRB-
cord-017161-lcqrd4v0	314	30	.	.	.
cord-017161-lcqrd4v0	315	1	Of	of	IN
cord-017161-lcqrd4v0	315	2	interest	interest	NN
cord-017161-lcqrd4v0	315	3	,	,	,
cord-017161-lcqrd4v0	315	4	two	two	CD
cord-017161-lcqrd4v0	315	5	recent	recent	JJ
cord-017161-lcqrd4v0	315	6	randomized	randomized	JJ
cord-017161-lcqrd4v0	315	7	control	control	NN
cord-017161-lcqrd4v0	315	8	trials	trial	NNS
cord-017161-lcqrd4v0	315	9	reported	report	VBN
cord-017161-lcqrd4v0	315	10	on	on	IN
cord-017161-lcqrd4v0	315	11	the	the	DT
cord-017161-lcqrd4v0	315	12	ef	ef	NNP
cord-017161-lcqrd4v0	315	13	fi	fi	NN
cord-017161-lcqrd4v0	315	14	cacy	cacy	NN
cord-017161-lcqrd4v0	315	15	of	of	IN
cord-017161-lcqrd4v0	315	16	rituximab	rituximab	NN
cord-017161-lcqrd4v0	315	17	compared	compare	VBN
cord-017161-lcqrd4v0	315	18	to	to	IN
cord-017161-lcqrd4v0	315	19	cyclophosphamide	cyclophosphamide	NN
cord-017161-lcqrd4v0	315	20	to	to	TO
cord-017161-lcqrd4v0	315	21	induce	induce	VB
cord-017161-lcqrd4v0	315	22	remission	remission	NN
cord-017161-lcqrd4v0	315	23	in	in	IN
cord-017161-lcqrd4v0	315	24	adults	adult	NNS
cord-017161-lcqrd4v0	315	25	with	with	IN
cord-017161-lcqrd4v0	315	26	AAV	AAV	NNP
cord-017161-lcqrd4v0	315	27	[	[	-LRB-
cord-017161-lcqrd4v0	315	28	184	184	CD
cord-017161-lcqrd4v0	315	29	,	,	,
cord-017161-lcqrd4v0	315	30	185	185	CD
cord-017161-lcqrd4v0	315	31	]	]	-RRB-
cord-017161-lcqrd4v0	315	32	.	.	.
cord-017161-lcqrd4v0	316	1	Jones	Jones	NNP
cord-017161-lcqrd4v0	316	2	et	et	NNP
cord-017161-lcqrd4v0	316	3	al	al	NNP
cord-017161-lcqrd4v0	316	4	.	.	.
cord-017161-lcqrd4v0	317	1	report	report	VB
cord-017161-lcqrd4v0	317	2	on	on	IN
cord-017161-lcqrd4v0	317	3	the	the	DT
cord-017161-lcqrd4v0	317	4	results	result	NNS
cord-017161-lcqrd4v0	317	5	of	of	IN
cord-017161-lcqrd4v0	317	6	a	a	DT
cord-017161-lcqrd4v0	317	7	randomized	randomized	JJ
cord-017161-lcqrd4v0	317	8	trial	trial	NN
cord-017161-lcqrd4v0	317	9	of	of	IN
cord-017161-lcqrd4v0	317	10	rituximab	rituximab	NN
cord-017161-lcqrd4v0	317	11	versus	versus	IN
cord-017161-lcqrd4v0	317	12	cyclophosphamide	cyclophosphamide	NN
cord-017161-lcqrd4v0	317	13	in	in	IN
cord-017161-lcqrd4v0	317	14	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	317	15	-	-	HYPH
cord-017161-lcqrd4v0	317	16	associated	associate	VBN
cord-017161-lcqrd4v0	317	17	renal	renal	JJ
cord-017161-lcqrd4v0	317	18	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	317	19	(	(	-LRB-
cord-017161-lcqrd4v0	317	20	RITUXIVAS	RITUXIVAS	NNP
cord-017161-lcqrd4v0	317	21	)	)	-RRB-
cord-017161-lcqrd4v0	317	22	and	and	CC
cord-017161-lcqrd4v0	317	23	Stone	Stone	NNP
cord-017161-lcqrd4v0	317	24	et	et	NNP
cord-017161-lcqrd4v0	317	25	al	al	NNP
cord-017161-lcqrd4v0	317	26	.	.	.
cord-017161-lcqrd4v0	318	1	report	report	VB
cord-017161-lcqrd4v0	318	2	on	on	IN
cord-017161-lcqrd4v0	318	3	the	the	DT
cord-017161-lcqrd4v0	318	4	results	result	NNS
cord-017161-lcqrd4v0	318	5	of	of	IN
cord-017161-lcqrd4v0	318	6	the	the	DT
cord-017161-lcqrd4v0	318	7	rituximab	rituximab	NN
cord-017161-lcqrd4v0	318	8	in	in	IN
cord-017161-lcqrd4v0	318	9	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	318	10	-	-	HYPH
cord-017161-lcqrd4v0	318	11	associated	associate	VBN
cord-017161-lcqrd4v0	318	12	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	318	13	(	(	-LRB-
cord-017161-lcqrd4v0	318	14	RAVE	RAVE	NNP
cord-017161-lcqrd4v0	318	15	)	)	-RRB-
cord-017161-lcqrd4v0	318	16	trial	trial	NN
cord-017161-lcqrd4v0	318	17	[	[	-LRB-
cord-017161-lcqrd4v0	318	18	184	184	CD
cord-017161-lcqrd4v0	318	19	,	,	,
cord-017161-lcqrd4v0	318	20	185	185	CD
cord-017161-lcqrd4v0	318	21	]	]	-RRB-
cord-017161-lcqrd4v0	318	22	.	.	.
cord-017161-lcqrd4v0	319	1	Similar	similar	JJ
cord-017161-lcqrd4v0	319	2	conclusions	conclusion	NNS
cord-017161-lcqrd4v0	319	3	are	be	VBP
cord-017161-lcqrd4v0	319	4	reached	reach	VBN
cord-017161-lcqrd4v0	319	5	in	in	IN
cord-017161-lcqrd4v0	319	6	the	the	DT
cord-017161-lcqrd4v0	319	7	two	two	CD
cord-017161-lcqrd4v0	319	8	studies	study	NNS
cord-017161-lcqrd4v0	319	9	[	[	-LRB-
cord-017161-lcqrd4v0	319	10	184	184	CD
cord-017161-lcqrd4v0	319	11	,	,	,
cord-017161-lcqrd4v0	319	12	185	185	CD
cord-017161-lcqrd4v0	319	13	]	]	-RRB-
cord-017161-lcqrd4v0	319	14	.	.	.
cord-017161-lcqrd4v0	320	1	Both	both	DT
cord-017161-lcqrd4v0	320	2	trials	trial	NNS
cord-017161-lcqrd4v0	320	3	showed	show	VBD
cord-017161-lcqrd4v0	320	4	that	that	IN
cord-017161-lcqrd4v0	320	5	rituximab	rituximab	NN
cord-017161-lcqrd4v0	320	6	was	be	VBD
cord-017161-lcqrd4v0	320	7	ef	ef	NNP
cord-017161-lcqrd4v0	320	8	fi	fi	NNP
cord-017161-lcqrd4v0	320	9	cacious	cacious	NNP
cord-017161-lcqrd4v0	320	10	in	in	IN
cord-017161-lcqrd4v0	320	11	inducing	induce	VBG
cord-017161-lcqrd4v0	320	12	a	a	DT
cord-017161-lcqrd4v0	320	13	remission	remission	NN
cord-017161-lcqrd4v0	320	14	,	,	,
cord-017161-lcqrd4v0	320	15	as	as	IN
cord-017161-lcqrd4v0	320	16	compared	compare	VBN
cord-017161-lcqrd4v0	320	17	with	with	IN
cord-017161-lcqrd4v0	320	18	intravenous	intravenous	JJ
cord-017161-lcqrd4v0	320	19	cyclophosphamide	cyclophosphamide	NN
cord-017161-lcqrd4v0	320	20	(	(	-LRB-
cord-017161-lcqrd4v0	320	21	in	in	IN
cord-017161-lcqrd4v0	320	22	the	the	DT
cord-017161-lcqrd4v0	320	23	RITUXIVAS	RITUXIVAS	NNP
cord-017161-lcqrd4v0	320	24	trial	trial	NN
cord-017161-lcqrd4v0	320	25	)	)	-RRB-
cord-017161-lcqrd4v0	320	26	or	or	CC
cord-017161-lcqrd4v0	320	27	oral	oral	JJ
cord-017161-lcqrd4v0	320	28	cyclophosphamide	cyclophosphamide	NN
cord-017161-lcqrd4v0	320	29	(	(	-LRB-
cord-017161-lcqrd4v0	320	30	in	in	IN
cord-017161-lcqrd4v0	320	31	the	the	DT
cord-017161-lcqrd4v0	320	32	RAVE	rave	NN
cord-017161-lcqrd4v0	320	33	trial	trial	NN
cord-017161-lcqrd4v0	320	34	)	)	-RRB-
cord-017161-lcqrd4v0	320	35	[	[	-LRB-
cord-017161-lcqrd4v0	320	36	184	184	CD
cord-017161-lcqrd4v0	320	37	,	,	,
cord-017161-lcqrd4v0	320	38	185	185	CD
cord-017161-lcqrd4v0	320	39	]	]	-RRB-
cord-017161-lcqrd4v0	320	40	.	.	.
cord-017161-lcqrd4v0	321	1	There	there	EX
cord-017161-lcqrd4v0	321	2	are	be	VBP
cord-017161-lcqrd4v0	321	3	,	,	,
cord-017161-lcqrd4v0	321	4	however	however	RB
cord-017161-lcqrd4v0	321	5	,	,	,
cord-017161-lcqrd4v0	321	6	a	a	DT
cord-017161-lcqrd4v0	321	7	number	number	NN
cord-017161-lcqrd4v0	321	8	of	of	IN
cord-017161-lcqrd4v0	321	9	important	important	JJ
cord-017161-lcqrd4v0	321	10	differences	difference	NNS
cord-017161-lcqrd4v0	321	11	between	between	IN
cord-017161-lcqrd4v0	321	12	the	the	DT
cord-017161-lcqrd4v0	321	13	two	two	CD
cord-017161-lcqrd4v0	321	14	trials	trial	NNS
cord-017161-lcqrd4v0	321	15	.	.	.
cord-017161-lcqrd4v0	322	1	In	in	IN
cord-017161-lcqrd4v0	322	2	the	the	DT
cord-017161-lcqrd4v0	322	3	RITUXIVAS	RITUXIVAS	NNP
cord-017161-lcqrd4v0	322	4	trial	trial	NN
cord-017161-lcqrd4v0	322	5	,	,	,
cord-017161-lcqrd4v0	322	6	patients	patient	NNS
cord-017161-lcqrd4v0	322	7	who	who	WP
cord-017161-lcqrd4v0	322	8	were	be	VBD
cord-017161-lcqrd4v0	322	9	randomly	randomly	RB
cord-017161-lcqrd4v0	322	10	assigned	assign	VBN
cord-017161-lcqrd4v0	322	11	to	to	IN
cord-017161-lcqrd4v0	322	12	the	the	DT
cord-017161-lcqrd4v0	322	13	rituximab	rituximab	NNP
cord-017161-lcqrd4v0	322	14	group	group	NN
cord-017161-lcqrd4v0	322	15	also	also	RB
cord-017161-lcqrd4v0	322	16	received	receive	VBD
cord-017161-lcqrd4v0	322	17	at	at	IN
cord-017161-lcqrd4v0	322	18	least	least	RBS
cord-017161-lcqrd4v0	322	19	two	two	CD
cord-017161-lcqrd4v0	322	20	doses	dose	NNS
cord-017161-lcqrd4v0	322	21	of	of	IN
cord-017161-lcqrd4v0	322	22	intravenous	intravenous	JJ
cord-017161-lcqrd4v0	322	23	cyclophosphamide	cyclophosphamide	NN
cord-017161-lcqrd4v0	322	24	,	,	,
cord-017161-lcqrd4v0	322	25	whereas	whereas	IN
cord-017161-lcqrd4v0	322	26	in	in	IN
cord-017161-lcqrd4v0	322	27	the	the	DT
cord-017161-lcqrd4v0	322	28	RAVE	rave	NN
cord-017161-lcqrd4v0	322	29	trial	trial	NN
cord-017161-lcqrd4v0	322	30	,	,	,
cord-017161-lcqrd4v0	322	31	patients	patient	NNS
cord-017161-lcqrd4v0	322	32	randomly	randomly	RB
cord-017161-lcqrd4v0	322	33	assigned	assign	VBN
cord-017161-lcqrd4v0	322	34	to	to	IN
cord-017161-lcqrd4v0	322	35	the	the	DT
cord-017161-lcqrd4v0	322	36	rituximab	rituximab	NNP
cord-017161-lcqrd4v0	322	37	group	group	NN
cord-017161-lcqrd4v0	322	38	did	do	VBD
cord-017161-lcqrd4v0	322	39	not	not	RB
cord-017161-lcqrd4v0	322	40	receive	receive	VB
cord-017161-lcqrd4v0	322	41	any	any	DT
cord-017161-lcqrd4v0	322	42	cyclophosphamide	cyclophosphamide	NN
cord-017161-lcqrd4v0	322	43	[	[	-LRB-
cord-017161-lcqrd4v0	322	44	184	184	CD
cord-017161-lcqrd4v0	322	45	,	,	,
cord-017161-lcqrd4v0	322	46	185	185	CD
cord-017161-lcqrd4v0	322	47	]	]	-RRB-
cord-017161-lcqrd4v0	322	48	.	.	.
cord-017161-lcqrd4v0	323	1	The	the	DT
cord-017161-lcqrd4v0	323	2	trials	trial	NNS
cord-017161-lcqrd4v0	323	3	were	be	VBD
cord-017161-lcqrd4v0	323	4	similar	similar	JJ
cord-017161-lcqrd4v0	323	5	in	in	IN
cord-017161-lcqrd4v0	323	6	that	that	IN
cord-017161-lcqrd4v0	323	7	all	all	DT
cord-017161-lcqrd4v0	323	8	patients	patient	NNS
cord-017161-lcqrd4v0	323	9	in	in	IN
cord-017161-lcqrd4v0	323	10	both	both	DT
cord-017161-lcqrd4v0	323	11	trials	trial	NNS
cord-017161-lcqrd4v0	323	12	received	receive	VBD
cord-017161-lcqrd4v0	323	13	both	both	DT
cord-017161-lcqrd4v0	323	14	intravenous	intravenous	JJ
cord-017161-lcqrd4v0	323	15	and	and	CC
cord-017161-lcqrd4v0	323	16	oral	oral	JJ
cord-017161-lcqrd4v0	323	17	glucocorticoid	glucocorticoid	NN
cord-017161-lcqrd4v0	323	18	therapy	therapy	NN
cord-017161-lcqrd4v0	323	19	[	[	-LRB-
cord-017161-lcqrd4v0	323	20	184	184	CD
cord-017161-lcqrd4v0	323	21	,	,	,
cord-017161-lcqrd4v0	323	22	185	185	CD
cord-017161-lcqrd4v0	323	23	]	]	-RRB-
cord-017161-lcqrd4v0	323	24	.	.	.
cord-017161-lcqrd4v0	324	1	Investigators	investigator	NNS
cord-017161-lcqrd4v0	324	2	in	in	IN
cord-017161-lcqrd4v0	324	3	the	the	DT
cord-017161-lcqrd4v0	324	4	RITUXIVAS	RITUXIVAS	NNP
cord-017161-lcqrd4v0	324	5	trial	trial	NN
cord-017161-lcqrd4v0	324	6	reported	report	VBD
cord-017161-lcqrd4v0	324	7	sustained	sustain	VBD
cord-017161-lcqrd4v0	324	8	remission	remission	NN
cord-017161-lcqrd4v0	324	9	for	for	IN
cord-017161-lcqrd4v0	324	10	12	12	CD
cord-017161-lcqrd4v0	324	11	months	month	NNS
cord-017161-lcqrd4v0	324	12	,	,	,
cord-017161-lcqrd4v0	324	13	whereas	whereas	IN
cord-017161-lcqrd4v0	324	14	outcome	outcome	NN
cord-017161-lcqrd4v0	324	15	data	datum	NNS
cord-017161-lcqrd4v0	324	16	from	from	IN
cord-017161-lcqrd4v0	324	17	the	the	DT
cord-017161-lcqrd4v0	324	18	RAVE	rave	NN
cord-017161-lcqrd4v0	324	19	trial	trial	NN
cord-017161-lcqrd4v0	324	20	were	be	VBD
cord-017161-lcqrd4v0	324	21	reported	report	VBN
cord-017161-lcqrd4v0	324	22	only	only	RB
cord-017161-lcqrd4v0	324	23	on	on	IN
cord-017161-lcqrd4v0	324	24	the	the	DT
cord-017161-lcqrd4v0	324	25	6-month	6-month	CD
cord-017161-lcqrd4v0	324	26	remission	remission	NN
cord-017161-lcqrd4v0	324	27	-	-	HYPH
cord-017161-lcqrd4v0	324	28	induction	induction	NN
cord-017161-lcqrd4v0	324	29	period	period	NN
cord-017161-lcqrd4v0	324	30	[	[	-LRB-
cord-017161-lcqrd4v0	324	31	184	184	CD
cord-017161-lcqrd4v0	324	32	,	,	,
cord-017161-lcqrd4v0	324	33	185	185	CD
cord-017161-lcqrd4v0	324	34	]	]	-RRB-
cord-017161-lcqrd4v0	324	35	.	.	.
cord-017161-lcqrd4v0	325	1	The	the	DT
cord-017161-lcqrd4v0	325	2	RAVE	rave	NN
cord-017161-lcqrd4v0	325	3	trial	trial	NN
cord-017161-lcqrd4v0	325	4	data	datum	NNS
cord-017161-lcqrd4v0	325	5	were	be	VBD
cord-017161-lcqrd4v0	325	6	confounded	confound	VBN
cord-017161-lcqrd4v0	325	7	by	by	IN
cord-017161-lcqrd4v0	325	8	the	the	DT
cord-017161-lcqrd4v0	325	9	use	use	NN
cord-017161-lcqrd4v0	325	10	of	of	IN
cord-017161-lcqrd4v0	325	11	glucocorticoid	glucocorticoid	NN
cord-017161-lcqrd4v0	325	12	therapy	therapy	NN
cord-017161-lcqrd4v0	325	13	for	for	IN
cord-017161-lcqrd4v0	325	14	5	5	CD
cord-017161-lcqrd4v0	325	15	of	of	IN
cord-017161-lcqrd4v0	325	16	the	the	DT
cord-017161-lcqrd4v0	325	17	6	6	CD
cord-017161-lcqrd4v0	325	18	months	month	NNS
cord-017161-lcqrd4v0	325	19	of	of	IN
cord-017161-lcqrd4v0	325	20	follow	follow	NN
cord-017161-lcqrd4v0	325	21	-	-	HYPH
cord-017161-lcqrd4v0	325	22	up	up	NN
cord-017161-lcqrd4v0	325	23	[	[	-LRB-
cord-017161-lcqrd4v0	325	24	185	185	CD
cord-017161-lcqrd4v0	325	25	]	]	-RRB-
cord-017161-lcqrd4v0	325	26	.	.	.
cord-017161-lcqrd4v0	326	1	In	in	IN
cord-017161-lcqrd4v0	326	2	addition	addition	NN
cord-017161-lcqrd4v0	326	3	,	,	,
cord-017161-lcqrd4v0	326	4	both	both	DT
cord-017161-lcqrd4v0	326	5	trials	trial	NNS
cord-017161-lcqrd4v0	326	6	raised	raise	VBD
cord-017161-lcqrd4v0	326	7	concerns	concern	NNS
cord-017161-lcqrd4v0	326	8	about	about	IN
cord-017161-lcqrd4v0	326	9	the	the	DT
cord-017161-lcqrd4v0	326	10	substantial	substantial	JJ
cord-017161-lcqrd4v0	326	11	complications	complication	NNS
cord-017161-lcqrd4v0	326	12	from	from	IN
cord-017161-lcqrd4v0	326	13	the	the	DT
cord-017161-lcqrd4v0	326	14	use	use	NN
cord-017161-lcqrd4v0	326	15	of	of	IN
cord-017161-lcqrd4v0	326	16	rituximab	rituximab	NN
cord-017161-lcqrd4v0	326	17	and	and	CC
cord-017161-lcqrd4v0	326	18	other	other	JJ
cord-017161-lcqrd4v0	326	19	immunomodulating	immunomodulating	JJ
cord-017161-lcqrd4v0	326	20	agents	agent	NNS
cord-017161-lcqrd4v0	326	21	in	in	IN
cord-017161-lcqrd4v0	326	22	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	326	23	-	-	HYPH
cord-017161-lcqrd4v0	326	24	associated	associate	VBN
cord-017161-lcqrd4v0	326	25	disease	disease	NN
cord-017161-lcqrd4v0	326	26	[	[	-LRB-
cord-017161-lcqrd4v0	326	27	184	184	CD
cord-017161-lcqrd4v0	326	28	,	,	,
cord-017161-lcqrd4v0	326	29	185	185	CD
cord-017161-lcqrd4v0	326	30	]	]	-RRB-
cord-017161-lcqrd4v0	326	31	.	.	.
cord-017161-lcqrd4v0	327	1	Fewer	few	JJR
cord-017161-lcqrd4v0	327	2	adverse	adverse	JJ
cord-017161-lcqrd4v0	327	3	events	event	NNS
cord-017161-lcqrd4v0	327	4	would	would	MD
cord-017161-lcqrd4v0	327	5	have	have	VB
cord-017161-lcqrd4v0	327	6	been	be	VBN
cord-017161-lcqrd4v0	327	7	expected	expect	VBN
cord-017161-lcqrd4v0	327	8	in	in	IN
cord-017161-lcqrd4v0	327	9	patients	patient	NNS
cord-017161-lcqrd4v0	327	10	treated	treat	VBN
cord-017161-lcqrd4v0	327	11	with	with	IN
cord-017161-lcqrd4v0	327	12	rituximab	rituximab	NN
cord-017161-lcqrd4v0	327	13	as	as	IN
cord-017161-lcqrd4v0	327	14	compared	compare	VBN
cord-017161-lcqrd4v0	327	15	with	with	IN
cord-017161-lcqrd4v0	327	16	cyclophosphamide	cyclophosphamide	NN
cord-017161-lcqrd4v0	327	17	.	.	.
cord-017161-lcqrd4v0	328	1	Unfortunately	unfortunately	RB
cord-017161-lcqrd4v0	328	2	,	,	,
cord-017161-lcqrd4v0	328	3	in	in	IN
cord-017161-lcqrd4v0	328	4	the	the	DT
cord-017161-lcqrd4v0	328	5	RAVE	rave	NN
cord-017161-lcqrd4v0	328	6	trial	trial	NN
cord-017161-lcqrd4v0	328	7	the	the	DT
cord-017161-lcqrd4v0	328	8	rate	rate	NN
cord-017161-lcqrd4v0	328	9	of	of	IN
cord-017161-lcqrd4v0	328	10	adverse	adverse	JJ
cord-017161-lcqrd4v0	328	11	events	event	NNS
cord-017161-lcqrd4v0	328	12	was	be	VBD
cord-017161-lcqrd4v0	328	13	equivalent	equivalent	JJ
cord-017161-lcqrd4v0	328	14	in	in	IN
cord-017161-lcqrd4v0	328	15	the	the	DT
cord-017161-lcqrd4v0	328	16	two	two	CD
cord-017161-lcqrd4v0	328	17	study	study	NN
cord-017161-lcqrd4v0	328	18	groups	group	NNS
cord-017161-lcqrd4v0	328	19	[	[	-LRB-
cord-017161-lcqrd4v0	328	20	185	185	CD
cord-017161-lcqrd4v0	328	21	]	]	-RRB-
cord-017161-lcqrd4v0	328	22	.	.	.
cord-017161-lcqrd4v0	329	1	Similarly	similarly	RB
cord-017161-lcqrd4v0	329	2	,	,	,
cord-017161-lcqrd4v0	329	3	in	in	IN
cord-017161-lcqrd4v0	329	4	the	the	DT
cord-017161-lcqrd4v0	329	5	RITUXIVAS	RITUXIVAS	NNP
cord-017161-lcqrd4v0	329	6	study	study	NN
cord-017161-lcqrd4v0	329	7	,	,	,
cord-017161-lcqrd4v0	329	8	6	6	CD
cord-017161-lcqrd4v0	329	9	of	of	IN
cord-017161-lcqrd4v0	329	10	33	33	CD
cord-017161-lcqrd4v0	329	11	patients	patient	NNS
cord-017161-lcqrd4v0	329	12	in	in	IN
cord-017161-lcqrd4v0	329	13	the	the	DT
cord-017161-lcqrd4v0	329	14	rituximab	rituximab	NNP
cord-017161-lcqrd4v0	329	15	group	group	NN
cord-017161-lcqrd4v0	329	16	died	die	VBD
cord-017161-lcqrd4v0	329	17	,	,	,
cord-017161-lcqrd4v0	329	18	as	as	IN
cord-017161-lcqrd4v0	329	19	did	do	VBD
cord-017161-lcqrd4v0	329	20	2	2	CD
cord-017161-lcqrd4v0	329	21	of	of	IN
cord-017161-lcqrd4v0	329	22	11	11	CD
cord-017161-lcqrd4v0	329	23	patients	patient	NNS
cord-017161-lcqrd4v0	329	24	in	in	IN
cord-017161-lcqrd4v0	329	25	the	the	DT
cord-017161-lcqrd4v0	329	26	control	control	NN
cord-017161-lcqrd4v0	329	27	group	group	NN
cord-017161-lcqrd4v0	329	28	[	[	-LRB-
cord-017161-lcqrd4v0	329	29	184	184	CD
cord-017161-lcqrd4v0	329	30	]	]	-RRB-
cord-017161-lcqrd4v0	329	31	.	.	.
cord-017161-lcqrd4v0	330	1	The	the	DT
cord-017161-lcqrd4v0	330	2	RAVE	rave	NN
cord-017161-lcqrd4v0	330	3	trial	trial	NN
cord-017161-lcqrd4v0	330	4	also	also	RB
cord-017161-lcqrd4v0	330	5	showed	show	VBD
cord-017161-lcqrd4v0	330	6	an	an	DT
cord-017161-lcqrd4v0	330	7	unexpectedly	unexpectedly	RB
cord-017161-lcqrd4v0	330	8	elevated	elevated	JJ
cord-017161-lcqrd4v0	330	9	number	number	NN
cord-017161-lcqrd4v0	330	10	of	of	IN
cord-017161-lcqrd4v0	330	11	malignant	malignant	JJ
cord-017161-lcqrd4v0	330	12	conditions	condition	NNS
cord-017161-lcqrd4v0	330	13	detected	detect	VBN
cord-017161-lcqrd4v0	330	14	over	over	IN
cord-017161-lcqrd4v0	330	15	a	a	DT
cord-017161-lcqrd4v0	330	16	relatively	relatively	RB
cord-017161-lcqrd4v0	330	17	short	short	JJ
cord-017161-lcqrd4v0	330	18	treatment	treatment	NN
cord-017161-lcqrd4v0	330	19	period	period	NN
cord-017161-lcqrd4v0	330	20	[	[	-LRB-
cord-017161-lcqrd4v0	330	21	185	185	CD
cord-017161-lcqrd4v0	330	22	]	]	-RRB-
cord-017161-lcqrd4v0	330	23	.	.	.
cord-017161-lcqrd4v0	331	1	These	these	DT
cord-017161-lcqrd4v0	331	2	studies	study	NNS
cord-017161-lcqrd4v0	331	3	suggest	suggest	VBP
cord-017161-lcqrd4v0	331	4	that	that	IN
cord-017161-lcqrd4v0	331	5	rituximab	rituximab	NN
cord-017161-lcqrd4v0	331	6	might	may	MD
cord-017161-lcqrd4v0	331	7	be	be	VB
cord-017161-lcqrd4v0	331	8	considered	consider	VBN
cord-017161-lcqrd4v0	331	9	as	as	IN
cord-017161-lcqrd4v0	331	10	an	an	DT
cord-017161-lcqrd4v0	331	11	option	option	NN
cord-017161-lcqrd4v0	331	12	for	for	IN
cord-017161-lcqrd4v0	331	13	fi	fi	NNP
cord-017161-lcqrd4v0	331	14	rst	rst	JJ
cord-017161-lcqrd4v0	331	15	-	-	HYPH
cord-017161-lcqrd4v0	331	16	line	line	NN
cord-017161-lcqrd4v0	331	17	therapy	therapy	NN
cord-017161-lcqrd4v0	331	18	for	for	IN
cord-017161-lcqrd4v0	331	19	induction	induction	NN
cord-017161-lcqrd4v0	331	20	of	of	IN
cord-017161-lcqrd4v0	331	21	remission	remission	NN
cord-017161-lcqrd4v0	331	22	of	of	IN
cord-017161-lcqrd4v0	331	23	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	331	24	-	-	HYPH
cord-017161-lcqrd4v0	331	25	associated	associate	VBN
cord-017161-lcqrd4v0	331	26	disease	disease	NN
cord-017161-lcqrd4v0	331	27	.	.	.
cord-017161-lcqrd4v0	332	1	It	-PRON-	PRP
cord-017161-lcqrd4v0	332	2	remains	remain	VBZ
cord-017161-lcqrd4v0	332	3	unclear	unclear	JJ
cord-017161-lcqrd4v0	332	4	whether	whether	IN
cord-017161-lcqrd4v0	332	5	rituximab	rituximab	NN
cord-017161-lcqrd4v0	332	6	should	should	MD
cord-017161-lcqrd4v0	332	7	be	be	VB
cord-017161-lcqrd4v0	332	8	used	use	VBN
cord-017161-lcqrd4v0	332	9	with	with	IN
cord-017161-lcqrd4v0	332	10	glucocorticoids	glucocorticoid	NNS
cord-017161-lcqrd4v0	332	11	alone	alone	RB
cord-017161-lcqrd4v0	332	12	or	or	CC
cord-017161-lcqrd4v0	332	13	in	in	IN
cord-017161-lcqrd4v0	332	14	combination	combination	NN
cord-017161-lcqrd4v0	332	15	with	with	IN
cord-017161-lcqrd4v0	332	16	intravenous	intravenous	JJ
cord-017161-lcqrd4v0	332	17	cyclophosphamide	cyclophosphamide	NN
cord-017161-lcqrd4v0	332	18	.	.	.
cord-017161-lcqrd4v0	333	1	Biologic	biologic	JJ
cord-017161-lcqrd4v0	333	2	therapy	therapy	NN
cord-017161-lcqrd4v0	333	3	is	be	VBZ
cord-017161-lcqrd4v0	333	4	also	also	RB
cord-017161-lcqrd4v0	333	5	increasingly	increasingly	RB
cord-017161-lcqrd4v0	333	6	used	use	VBN
cord-017161-lcqrd4v0	333	7	to	to	TO
cord-017161-lcqrd4v0	333	8	treat	treat	VB
cord-017161-lcqrd4v0	333	9	children	child	NNS
cord-017161-lcqrd4v0	333	10	with	with	IN
cord-017161-lcqrd4v0	333	11	small	small	JJ
cord-017161-lcqrd4v0	333	12	vessel	vessel	NN
cord-017161-lcqrd4v0	333	13	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	333	14	,	,	,
cord-017161-lcqrd4v0	333	15	including	include	VBG
cord-017161-lcqrd4v0	333	16	AAV	AAV	NNP
cord-017161-lcqrd4v0	333	17	and	and	CC
cord-017161-lcqrd4v0	333	18	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	333	19	negative	negative	JJ
cord-017161-lcqrd4v0	333	20	vasculitides	vasculitide	NNS
cord-017161-lcqrd4v0	333	21	[	[	-LRB-
cord-017161-lcqrd4v0	333	22	186	186	CD
cord-017161-lcqrd4v0	333	23	]	]	-RRB-
cord-017161-lcqrd4v0	333	24	.	.	.
cord-017161-lcqrd4v0	334	1	Agents	agent	NNS
cord-017161-lcqrd4v0	334	2	used	use	VBN
cord-017161-lcqrd4v0	334	3	include	include	VBP
cord-017161-lcqrd4v0	334	4	rituximab	rituximab	VBN
cord-017161-lcqrd4v0	334	5	(	(	-LRB-
cord-017161-lcqrd4v0	334	6	previously	previously	RB
cord-017161-lcqrd4v0	334	7	mentioned	mention	VBN
cord-017161-lcqrd4v0	334	8	)	)	-RRB-
cord-017161-lcqrd4v0	334	9	,	,	,
cord-017161-lcqrd4v0	334	10	anti	anti	JJ
cord-017161-lcqrd4v0	334	11	-	-	JJ
cord-017161-lcqrd4v0	334	12	TNF	TNF	NNP
cord-017161-lcqrd4v0	334	13	-	-	HYPH
cord-017161-lcqrd4v0	334	14	a	a	NN
cord-017161-lcqrd4v0	334	15	(	(	-LRB-
cord-017161-lcqrd4v0	334	16	etanercept	etanercept	NNP
cord-017161-lcqrd4v0	334	17	,	,	,
cord-017161-lcqrd4v0	334	18	in	in	IN
cord-017161-lcqrd4v0	334	19	fl	fl	NNP
cord-017161-lcqrd4v0	334	20	iximab	iximab	NNS
cord-017161-lcqrd4v0	334	21	,	,	,
cord-017161-lcqrd4v0	334	22	and	and	CC
cord-017161-lcqrd4v0	334	23	adalimumab	adalimumab	NNP
cord-017161-lcqrd4v0	334	24	)	)	-RRB-
cord-017161-lcqrd4v0	334	25	,	,	,
cord-017161-lcqrd4v0	334	26	and	and	CC
cord-017161-lcqrd4v0	334	27	anakinra	anakinra	NNP
cord-017161-lcqrd4v0	334	28	(	(	-LRB-
cord-017161-lcqrd4v0	334	29	recombinant	recombinant	JJ
cord-017161-lcqrd4v0	334	30	interleukin	interleukin	NN
cord-017161-lcqrd4v0	334	31	1	1	CD
cord-017161-lcqrd4v0	334	32	receptor	receptor	NN
cord-017161-lcqrd4v0	334	33	antagonist	antagonist	NN
cord-017161-lcqrd4v0	334	34	)	)	-RRB-
cord-017161-lcqrd4v0	334	35	[	[	-LRB-
cord-017161-lcqrd4v0	334	36	186	186	CD
cord-017161-lcqrd4v0	334	37	]	]	-RRB-
cord-017161-lcqrd4v0	334	38	.	.	.
cord-017161-lcqrd4v0	335	1	These	these	DT
cord-017161-lcqrd4v0	335	2	therapies	therapy	NNS
cord-017161-lcqrd4v0	335	3	are	be	VBP
cord-017161-lcqrd4v0	335	4	mainly	mainly	RB
cord-017161-lcqrd4v0	335	5	reserved	reserve	VBN
cord-017161-lcqrd4v0	335	6	for	for	IN
cord-017161-lcqrd4v0	335	7	those	those	DT
cord-017161-lcqrd4v0	335	8	children	child	NNS
cord-017161-lcqrd4v0	335	9	who	who	WP
cord-017161-lcqrd4v0	335	10	have	have	VBP
cord-017161-lcqrd4v0	335	11	failed	fail	VBN
cord-017161-lcqrd4v0	335	12	standard	standard	JJ
cord-017161-lcqrd4v0	335	13	treatment	treatment	NN
cord-017161-lcqrd4v0	335	14	,	,	,
cord-017161-lcqrd4v0	335	15	or	or	CC
cord-017161-lcqrd4v0	335	16	in	in	IN
cord-017161-lcqrd4v0	335	17	those	those	DT
cord-017161-lcqrd4v0	335	18	patients	patient	NNS
cord-017161-lcqrd4v0	335	19	where	where	WRB
cord-017161-lcqrd4v0	335	20	cumulative	cumulative	JJ
cord-017161-lcqrd4v0	335	21	cyclophosphamide	cyclophosphamide	NN
cord-017161-lcqrd4v0	335	22	and/or	and/or	CC
cord-017161-lcqrd4v0	335	23	corticosteroid	corticosteroid	NN
cord-017161-lcqrd4v0	335	24	toxicity	toxicity	NN
cord-017161-lcqrd4v0	335	25	is	be	VBZ
cord-017161-lcqrd4v0	335	26	of	of	IN
cord-017161-lcqrd4v0	335	27	particular	particular	JJ
cord-017161-lcqrd4v0	335	28	concern	concern	NN
cord-017161-lcqrd4v0	335	29	[	[	-LRB-
cord-017161-lcqrd4v0	335	30	186	186	CD
cord-017161-lcqrd4v0	335	31	]	]	-RRB-
cord-017161-lcqrd4v0	335	32	.	.	.
cord-017161-lcqrd4v0	336	1	Of	of	IN
cord-017161-lcqrd4v0	336	2	note	note	NN
cord-017161-lcqrd4v0	336	3	is	be	VBZ
cord-017161-lcqrd4v0	336	4	the	the	DT
cord-017161-lcqrd4v0	336	5	European	european	JJ
cord-017161-lcqrd4v0	336	6	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	336	7	study	study	NN
cord-017161-lcqrd4v0	336	8	group	group	NN
cord-017161-lcqrd4v0	336	9	(	(	-LRB-
cord-017161-lcqrd4v0	336	10	EUVAS	EUVAS	NNP
cord-017161-lcqrd4v0	336	11	)	)	-RRB-
cord-017161-lcqrd4v0	337	1	MYCYC	MYCYC	NNP
cord-017161-lcqrd4v0	337	2	trial	trial	NN
cord-017161-lcqrd4v0	337	3	(	(	-LRB-
cord-017161-lcqrd4v0	337	4	UK	UK	NNP
cord-017161-lcqrd4v0	337	5	and	and	CC
cord-017161-lcqrd4v0	337	6	Europe	Europe	NNP
cord-017161-lcqrd4v0	337	7	)	)	-RRB-
cord-017161-lcqrd4v0	337	8	,	,	,
cord-017161-lcqrd4v0	337	9	which	which	WDT
cord-017161-lcqrd4v0	337	10	is	be	VBZ
cord-017161-lcqrd4v0	337	11	comparing	compare	VBG
cord-017161-lcqrd4v0	337	12	induction	induction	NN
cord-017161-lcqrd4v0	337	13	therapy	therapy	NN
cord-017161-lcqrd4v0	337	14	of	of	IN
cord-017161-lcqrd4v0	337	15	WG	WG	NNP
cord-017161-lcqrd4v0	337	16	and	and	CC
cord-017161-lcqrd4v0	337	17	MPA	MPA	NNP
cord-017161-lcqrd4v0	337	18	using	use	VBG
cord-017161-lcqrd4v0	337	19	cyclophosphamide	cyclophosphamide	RB
cord-017161-lcqrd4v0	337	20	(	(	-LRB-
cord-017161-lcqrd4v0	337	21	standard	standard	JJ
cord-017161-lcqrd4v0	337	22	therapy	therapy	NN
cord-017161-lcqrd4v0	337	23	)	)	-RRB-
cord-017161-lcqrd4v0	337	24	versus	versus	IN
cord-017161-lcqrd4v0	337	25	MMF	MMF	NNP
cord-017161-lcqrd4v0	337	26	(	(	-LRB-
cord-017161-lcqrd4v0	337	27	experimental	experimental	JJ
cord-017161-lcqrd4v0	337	28	therapy	therapy	NN
cord-017161-lcqrd4v0	337	29	)	)	-RRB-
cord-017161-lcqrd4v0	337	30	.	.	.
cord-017161-lcqrd4v0	338	1	This	this	DT
cord-017161-lcqrd4v0	338	2	is	be	VBZ
cord-017161-lcqrd4v0	338	3	the	the	DT
cord-017161-lcqrd4v0	338	4	fi	fi	NN
cord-017161-lcqrd4v0	338	5	rst	rst	NNP
cord-017161-lcqrd4v0	338	6	EUVAS	EUVAS	NNP
cord-017161-lcqrd4v0	338	7	trial	trial	NN
cord-017161-lcqrd4v0	338	8	to	to	TO
cord-017161-lcqrd4v0	338	9	include	include	VB
cord-017161-lcqrd4v0	338	10	children	child	NNS
cord-017161-lcqrd4v0	338	11	as	as	RB
cord-017161-lcqrd4v0	338	12	well	well	RB
cord-017161-lcqrd4v0	338	13	as	as	IN
cord-017161-lcqrd4v0	338	14	adults	adult	NNS
cord-017161-lcqrd4v0	338	15	and	and	CC
cord-017161-lcqrd4v0	338	16	is	be	VBZ
cord-017161-lcqrd4v0	338	17	actively	actively	RB
cord-017161-lcqrd4v0	338	18	recruiting	recruit	VBG
cord-017161-lcqrd4v0	338	19	patients	patient	NNS
cord-017161-lcqrd4v0	338	20	under	under	IN
cord-017161-lcqrd4v0	338	21	the	the	DT
cord-017161-lcqrd4v0	338	22	age	age	NN
cord-017161-lcqrd4v0	338	23	of	of	IN
cord-017161-lcqrd4v0	338	24	17	17	CD
cord-017161-lcqrd4v0	338	25	years	year	NNS
cord-017161-lcqrd4v0	338	26	in	in	IN
cord-017161-lcqrd4v0	338	27	the	the	DT
cord-017161-lcqrd4v0	338	28	UK	UK	NNP
cord-017161-lcqrd4v0	338	29	.	.	.
cord-017161-lcqrd4v0	339	1	For	for	IN
cord-017161-lcqrd4v0	339	2	a	a	DT
cord-017161-lcqrd4v0	339	3	full	full	JJ
cord-017161-lcqrd4v0	339	4	list	list	NN
cord-017161-lcqrd4v0	339	5	of	of	IN
cord-017161-lcqrd4v0	339	6	the	the	DT
cord-017161-lcqrd4v0	339	7	past	past	NN
cord-017161-lcqrd4v0	339	8	and	and	CC
cord-017161-lcqrd4v0	339	9	present	present	JJ
cord-017161-lcqrd4v0	339	10	EUVAS	EUVAS	NNP
cord-017161-lcqrd4v0	339	11	trials	trial	NNS
cord-017161-lcqrd4v0	339	12	for	for	IN
cord-017161-lcqrd4v0	339	13	AVV	AVV	NNP
cord-017161-lcqrd4v0	339	14	,	,	,
cord-017161-lcqrd4v0	339	15	the	the	DT
cord-017161-lcqrd4v0	339	16	reader	reader	NN
cord-017161-lcqrd4v0	339	17	is	be	VBZ
cord-017161-lcqrd4v0	339	18	directed	direct	VBN
cord-017161-lcqrd4v0	339	19	to	to	IN
cord-017161-lcqrd4v0	339	20	:	:	:
cord-017161-lcqrd4v0	339	21	http://www.vasculitis.org/	http://www.vasculitis.org/	ADD
cord-017161-lcqrd4v0	339	22	.	.	.
cord-017161-lcqrd4v0	340	1	The	the	DT
cord-017161-lcqrd4v0	340	2	AAV	AAV	NNP
cord-017161-lcqrd4v0	340	3	still	still	RB
cord-017161-lcqrd4v0	340	4	carry	carry	VBP
cord-017161-lcqrd4v0	340	5	considerable	considerable	JJ
cord-017161-lcqrd4v0	340	6	disease	disease	NN
cord-017161-lcqrd4v0	340	7	-	-	HYPH
cord-017161-lcqrd4v0	340	8	related	relate	VBN
cord-017161-lcqrd4v0	340	9	morbidity	morbidity	NN
cord-017161-lcqrd4v0	340	10	and	and	CC
cord-017161-lcqrd4v0	340	11	mortality	mortality	NN
cord-017161-lcqrd4v0	340	12	,	,	,
cord-017161-lcqrd4v0	340	13	particularly	particularly	RB
cord-017161-lcqrd4v0	340	14	due	due	JJ
cord-017161-lcqrd4v0	340	15	to	to	IN
cord-017161-lcqrd4v0	340	16	progressive	progressive	JJ
cord-017161-lcqrd4v0	340	17	renal	renal	JJ
cord-017161-lcqrd4v0	340	18	failure	failure	NN
cord-017161-lcqrd4v0	340	19	or	or	CC
cord-017161-lcqrd4v0	340	20	aggressive	aggressive	JJ
cord-017161-lcqrd4v0	340	21	respiratory	respiratory	JJ
cord-017161-lcqrd4v0	340	22	involvement	involvement	NN
cord-017161-lcqrd4v0	340	23	,	,	,
cord-017161-lcqrd4v0	340	24	and	and	CC
cord-017161-lcqrd4v0	340	25	therapy	therapy	NN
cord-017161-lcqrd4v0	340	26	-	-	HYPH
cord-017161-lcqrd4v0	340	27	related	relate	VBN
cord-017161-lcqrd4v0	340	28	complications	complication	NNS
cord-017161-lcqrd4v0	340	29	such	such	JJ
cord-017161-lcqrd4v0	340	30	as	as	IN
cord-017161-lcqrd4v0	340	31	sepsis	sepsis	NN
cord-017161-lcqrd4v0	340	32	.	.	.
cord-017161-lcqrd4v0	341	1	The	the	DT
cord-017161-lcqrd4v0	341	2	mortality	mortality	NN
cord-017161-lcqrd4v0	341	3	for	for	IN
cord-017161-lcqrd4v0	341	4	paediatric	paediatric	JJ
cord-017161-lcqrd4v0	341	5	WG	WG	NNP
cord-017161-lcqrd4v0	341	6	from	from	IN
cord-017161-lcqrd4v0	341	7	one	one	CD
cord-017161-lcqrd4v0	341	8	recent	recent	JJ
cord-017161-lcqrd4v0	341	9	paediatric	paediatric	JJ
cord-017161-lcqrd4v0	341	10	series	series	NN
cord-017161-lcqrd4v0	341	11	was	be	VBD
cord-017161-lcqrd4v0	341	12	12	12	CD
cord-017161-lcqrd4v0	341	13	%	%	NN
cord-017161-lcqrd4v0	341	14	over	over	IN
cord-017161-lcqrd4v0	341	15	a	a	DT
cord-017161-lcqrd4v0	341	16	17-year	17-year	JJ
cord-017161-lcqrd4v0	341	17	period	period	NN
cord-017161-lcqrd4v0	341	18	of	of	IN
cord-017161-lcqrd4v0	341	19	study	study	NN
cord-017161-lcqrd4v0	341	20	inclusion	inclusion	NN
cord-017161-lcqrd4v0	341	21	[	[	-LRB-
cord-017161-lcqrd4v0	341	22	187	187	CD
cord-017161-lcqrd4v0	341	23	]	]	-RRB-
cord-017161-lcqrd4v0	341	24	.	.	.
cord-017161-lcqrd4v0	342	1	The	the	DT
cord-017161-lcqrd4v0	342	2	largest	large	JJS
cord-017161-lcqrd4v0	342	3	paediatric	paediatric	JJ
cord-017161-lcqrd4v0	342	4	series	series	NN
cord-017161-lcqrd4v0	342	5	of	of	IN
cord-017161-lcqrd4v0	342	6	WG	WG	NNP
cord-017161-lcqrd4v0	342	7	reported	report	VBD
cord-017161-lcqrd4v0	342	8	40	40	CD
cord-017161-lcqrd4v0	342	9	%	%	NN
cord-017161-lcqrd4v0	342	10	of	of	IN
cord-017161-lcqrd4v0	342	11	cases	case	NNS
cord-017161-lcqrd4v0	342	12	with	with	IN
cord-017161-lcqrd4v0	342	13	chronic	chronic	JJ
cord-017161-lcqrd4v0	342	14	renal	renal	JJ
cord-017161-lcqrd4v0	342	15	impairment	impairment	NN
cord-017161-lcqrd4v0	342	16	at	at	IN
cord-017161-lcqrd4v0	342	17	33	33	CD
cord-017161-lcqrd4v0	342	18	months	month	NNS
cord-017161-lcqrd4v0	342	19	follow	follow	VBP
cord-017161-lcqrd4v0	342	20	up	up	RP
cord-017161-lcqrd4v0	342	21	despite	despite	IN
cord-017161-lcqrd4v0	342	22	therapy	therapy	NN
cord-017161-lcqrd4v0	342	23	[	[	-LRB-
cord-017161-lcqrd4v0	342	24	188	188	CD
cord-017161-lcqrd4v0	342	25	]	]	-RRB-
cord-017161-lcqrd4v0	342	26	.	.	.
cord-017161-lcqrd4v0	343	1	For	for	IN
cord-017161-lcqrd4v0	343	2	MPA	MPA	NNP
cord-017161-lcqrd4v0	343	3	in	in	IN
cord-017161-lcqrd4v0	343	4	children	child	NNS
cord-017161-lcqrd4v0	343	5	,	,	,
cord-017161-lcqrd4v0	343	6	mortality	mortality	NN
cord-017161-lcqrd4v0	343	7	during	during	IN
cord-017161-lcqrd4v0	343	8	paediatric	paediatric	JJ
cord-017161-lcqrd4v0	343	9	follow	follow	NN
cord-017161-lcqrd4v0	343	10	up	up	RP
cord-017161-lcqrd4v0	343	11	is	be	VBZ
cord-017161-lcqrd4v0	343	12	reportedly	reportedly	RB
cord-017161-lcqrd4v0	343	13	less	less	JJR
cord-017161-lcqrd4v0	343	14	than	than	IN
cord-017161-lcqrd4v0	343	15	14	14	CD
cord-017161-lcqrd4v0	343	16	%	%	NN
cord-017161-lcqrd4v0	343	17	[	[	-LRB-
cord-017161-lcqrd4v0	343	18	189	189	CD
cord-017161-lcqrd4v0	343	19	]	]	-RRB-
cord-017161-lcqrd4v0	343	20	.	.	.
cord-017161-lcqrd4v0	344	1	For	for	IN
cord-017161-lcqrd4v0	344	2	CSS	css	NN
cord-017161-lcqrd4v0	344	3	in	in	IN
cord-017161-lcqrd4v0	344	4	children	child	NNS
cord-017161-lcqrd4v0	344	5	,	,	,
cord-017161-lcqrd4v0	344	6	the	the	DT
cord-017161-lcqrd4v0	344	7	most	most	RBS
cord-017161-lcqrd4v0	344	8	recent	recent	JJ
cord-017161-lcqrd4v0	344	9	series	series	NN
cord-017161-lcqrd4v0	344	10	quotes	quote	VBZ
cord-017161-lcqrd4v0	344	11	a	a	DT
cord-017161-lcqrd4v0	344	12	related	related	JJ
cord-017161-lcqrd4v0	344	13	mortality	mortality	NN
cord-017161-lcqrd4v0	344	14	of	of	IN
cord-017161-lcqrd4v0	344	15	18	18	CD
cord-017161-lcqrd4v0	344	16	%	%	NN
cord-017161-lcqrd4v0	344	17	,	,	,
cord-017161-lcqrd4v0	344	18	all	all	DT
cord-017161-lcqrd4v0	344	19	attributed	attribute	VBN
cord-017161-lcqrd4v0	344	20	to	to	IN
cord-017161-lcqrd4v0	344	21	disease	disease	NN
cord-017161-lcqrd4v0	344	22	rather	rather	RB
cord-017161-lcqrd4v0	344	23	than	than	IN
cord-017161-lcqrd4v0	344	24	therapy	therapy	NN
cord-017161-lcqrd4v0	344	25	[	[	-LRB-
cord-017161-lcqrd4v0	344	26	190	190	CD
cord-017161-lcqrd4v0	344	27	]	]	-RRB-
cord-017161-lcqrd4v0	344	28	.	.	.
cord-017161-lcqrd4v0	345	1	Systemic	systemic	JJ
cord-017161-lcqrd4v0	345	2	polyarteritis	polyarteritis	NN
cord-017161-lcqrd4v0	345	3	nodosa	nodosa	RB
cord-017161-lcqrd4v0	345	4	(	(	-LRB-
cord-017161-lcqrd4v0	345	5	PAN	PAN	NNP
cord-017161-lcqrd4v0	345	6	)	)	-RRB-
cord-017161-lcqrd4v0	345	7	is	be	VBZ
cord-017161-lcqrd4v0	345	8	rare	rare	JJ
cord-017161-lcqrd4v0	345	9	in	in	IN
cord-017161-lcqrd4v0	345	10	childhood	childhood	NN
cord-017161-lcqrd4v0	345	11	.	.	.
cord-017161-lcqrd4v0	346	1	Although	although	IN
cord-017161-lcqrd4v0	346	2	the	the	DT
cord-017161-lcqrd4v0	346	3	epidemiology	epidemiology	NN
cord-017161-lcqrd4v0	346	4	is	be	VBZ
cord-017161-lcqrd4v0	346	5	poorly	poorly	RB
cord-017161-lcqrd4v0	346	6	de	de	FW
cord-017161-lcqrd4v0	346	7	fi	fi	NNP
cord-017161-lcqrd4v0	346	8	ned	ned	NNP
cord-017161-lcqrd4v0	346	9	,	,	,
cord-017161-lcqrd4v0	346	10	PAN	PAN	NNP
cord-017161-lcqrd4v0	346	11	occurs	occur	VBZ
cord-017161-lcqrd4v0	346	12	more	more	RBR
cord-017161-lcqrd4v0	346	13	commonly	commonly	RB
cord-017161-lcqrd4v0	346	14	in	in	IN
cord-017161-lcqrd4v0	346	15	children	child	NNS
cord-017161-lcqrd4v0	346	16	than	than	IN
cord-017161-lcqrd4v0	346	17	in	in	IN
cord-017161-lcqrd4v0	346	18	adults	adult	NNS
cord-017161-lcqrd4v0	346	19	,	,	,
cord-017161-lcqrd4v0	346	20	as	as	RB
cord-017161-lcqrd4v0	346	21	well	well	RB
cord-017161-lcqrd4v0	346	22	as	as	IN
cord-017161-lcqrd4v0	346	23	being	be	VBG
cord-017161-lcqrd4v0	346	24	more	more	RBR
cord-017161-lcqrd4v0	346	25	common	common	JJ
cord-017161-lcqrd4v0	346	26	than	than	IN
cord-017161-lcqrd4v0	346	27	the	the	DT
cord-017161-lcqrd4v0	346	28	AAV	AAV	NNP
cord-017161-lcqrd4v0	346	29	[	[	-LRB-
cord-017161-lcqrd4v0	346	30	56	56	CD
cord-017161-lcqrd4v0	346	31	]	]	-RRB-
cord-017161-lcqrd4v0	346	32	.	.	.
cord-017161-lcqrd4v0	347	1	Disease	Disease	NNP
cord-017161-lcqrd4v0	347	2	manifestations	manifestation	NNS
cord-017161-lcqrd4v0	347	3	are	be	VBP
cord-017161-lcqrd4v0	347	4	diverse	diverse	JJ
cord-017161-lcqrd4v0	347	5	and	and	CC
cord-017161-lcqrd4v0	347	6	complex	complex	JJ
cord-017161-lcqrd4v0	347	7	,	,	,
cord-017161-lcqrd4v0	347	8	ranging	range	VBG
cord-017161-lcqrd4v0	347	9	from	from	IN
cord-017161-lcqrd4v0	347	10	the	the	DT
cord-017161-lcqrd4v0	347	11	benign	benign	JJ
cord-017161-lcqrd4v0	347	12	cutaneous	cutaneous	JJ
cord-017161-lcqrd4v0	347	13	form	form	NN
cord-017161-lcqrd4v0	347	14	to	to	IN
cord-017161-lcqrd4v0	347	15	the	the	DT
cord-017161-lcqrd4v0	347	16	severe	severe	JJ
cord-017161-lcqrd4v0	347	17	disseminated	disseminate	VBN
cord-017161-lcqrd4v0	347	18	multi	multi	JJ
cord-017161-lcqrd4v0	347	19	-	-	JJ
cord-017161-lcqrd4v0	347	20	systemic	systemic	JJ
cord-017161-lcqrd4v0	347	21	form	form	NN
cord-017161-lcqrd4v0	347	22	[	[	-LRB-
cord-017161-lcqrd4v0	347	23	56	56	CD
cord-017161-lcqrd4v0	347	24	]	]	-RRB-
cord-017161-lcqrd4v0	347	25	.	.	.
cord-017161-lcqrd4v0	348	1	The	the	DT
cord-017161-lcqrd4v0	348	2	immunopathogenesis	immunopathogenesis	NN
cord-017161-lcqrd4v0	348	3	leading	lead	VBG
cord-017161-lcqrd4v0	348	4	to	to	IN
cord-017161-lcqrd4v0	348	5	vascular	vascular	JJ
cord-017161-lcqrd4v0	348	6	injury	injury	NN
cord-017161-lcqrd4v0	348	7	in	in	IN
cord-017161-lcqrd4v0	348	8	PAN	PAN	NNP
cord-017161-lcqrd4v0	348	9	is	be	VBZ
cord-017161-lcqrd4v0	348	10	probably	probably	RB
cord-017161-lcqrd4v0	348	11	heterogeneous	heterogeneous	JJ
cord-017161-lcqrd4v0	348	12	[	[	-LRB-
cord-017161-lcqrd4v0	348	13	56	56	CD
cord-017161-lcqrd4v0	348	14	]	]	-RRB-
cord-017161-lcqrd4v0	348	15	.	.	.
cord-017161-lcqrd4v0	349	1	Based	base	VBN
cord-017161-lcqrd4v0	349	2	on	on	IN
cord-017161-lcqrd4v0	349	3	animal	animal	NN
cord-017161-lcqrd4v0	349	4	models	model	NNS
cord-017161-lcqrd4v0	349	5	,	,	,
cord-017161-lcqrd4v0	349	6	the	the	DT
cord-017161-lcqrd4v0	349	7	mechanism	mechanism	NN
cord-017161-lcqrd4v0	349	8	of	of	IN
cord-017161-lcqrd4v0	349	9	vascular	vascular	JJ
cord-017161-lcqrd4v0	349	10	in	in	IN
cord-017161-lcqrd4v0	349	11	fl	fl	NNP
cord-017161-lcqrd4v0	349	12	ammation	ammation	NNP
cord-017161-lcqrd4v0	349	13	implicated	implicate	VBD
cord-017161-lcqrd4v0	349	14	most	most	RBS
cord-017161-lcqrd4v0	349	15	often	often	RB
cord-017161-lcqrd4v0	349	16	is	be	VBZ
cord-017161-lcqrd4v0	349	17	induction	induction	NN
cord-017161-lcqrd4v0	349	18	by	by	IN
cord-017161-lcqrd4v0	349	19	immune	immune	JJ
cord-017161-lcqrd4v0	349	20	complexes	complex	NNS
cord-017161-lcqrd4v0	349	21	[	[	-LRB-
cord-017161-lcqrd4v0	349	22	56	56	CD
cord-017161-lcqrd4v0	349	23	]	]	-RRB-
cord-017161-lcqrd4v0	349	24	.	.	.
cord-017161-lcqrd4v0	350	1	In	in	IN
cord-017161-lcqrd4v0	350	2	addition	addition	NN
cord-017161-lcqrd4v0	350	3	,	,	,
cord-017161-lcqrd4v0	350	4	there	there	EX
cord-017161-lcqrd4v0	350	5	are	be	VBP
cord-017161-lcqrd4v0	350	6	some	some	DT
cord-017161-lcqrd4v0	350	7	data	datum	NNS
cord-017161-lcqrd4v0	350	8	supporting	support	VBG
cord-017161-lcqrd4v0	350	9	a	a	DT
cord-017161-lcqrd4v0	350	10	role	role	NN
cord-017161-lcqrd4v0	350	11	for	for	IN
cord-017161-lcqrd4v0	350	12	hepatitis	hepatitis	NN
cord-017161-lcqrd4v0	350	13	B	B	NNP
cord-017161-lcqrd4v0	350	14	in	in	IN
cord-017161-lcqrd4v0	350	15	some	some	DT
cord-017161-lcqrd4v0	350	16	patients	patient	NNS
cord-017161-lcqrd4v0	350	17	[	[	-LRB-
cord-017161-lcqrd4v0	350	18	191	191	CD
cord-017161-lcqrd4v0	350	19	]	]	-RRB-
cord-017161-lcqrd4v0	350	20	and	and	CC
cord-017161-lcqrd4v0	350	21	reports	report	NNS
cord-017161-lcqrd4v0	350	22	of	of	IN
cord-017161-lcqrd4v0	350	23	a	a	DT
cord-017161-lcqrd4v0	350	24	higher	high	JJR
cord-017161-lcqrd4v0	350	25	frequency	frequency	NN
cord-017161-lcqrd4v0	350	26	of	of	IN
cord-017161-lcqrd4v0	350	27	exposure	exposure	NN
cord-017161-lcqrd4v0	350	28	to	to	IN
cord-017161-lcqrd4v0	350	29	parvovirus	parvovirus	NN
cord-017161-lcqrd4v0	350	30	B19	B19	NNP
cord-017161-lcqrd4v0	350	31	and	and	CC
cord-017161-lcqrd4v0	350	32	cytomegalovirus	cytomegalovirus	NN
cord-017161-lcqrd4v0	350	33	in	in	IN
cord-017161-lcqrd4v0	350	34	PAN	PAN	NNP
cord-017161-lcqrd4v0	350	35	patients	patient	NNS
cord-017161-lcqrd4v0	350	36	compared	compare	VBN
cord-017161-lcqrd4v0	350	37	to	to	IN
cord-017161-lcqrd4v0	350	38	control	control	NN
cord-017161-lcqrd4v0	350	39	populations	population	NNS
cord-017161-lcqrd4v0	350	40	[	[	-LRB-
cord-017161-lcqrd4v0	350	41	192	192	CD
cord-017161-lcqrd4v0	350	42	,	,	,
cord-017161-lcqrd4v0	350	43	193	193	CD
cord-017161-lcqrd4v0	350	44	]	]	-RRB-
cord-017161-lcqrd4v0	350	45	.	.	.
cord-017161-lcqrd4v0	351	1	HIV	HIV	NNP
cord-017161-lcqrd4v0	351	2	has	have	VBZ
cord-017161-lcqrd4v0	351	3	also	also	RB
cord-017161-lcqrd4v0	351	4	been	be	VBN
cord-017161-lcqrd4v0	351	5	implicated	implicate	VBN
cord-017161-lcqrd4v0	351	6	and	and	CC
cord-017161-lcqrd4v0	351	7	PAN	pan	JJ
cord-017161-lcqrd4v0	351	8	-	-	HYPH
cord-017161-lcqrd4v0	351	9	like	like	JJ
cord-017161-lcqrd4v0	351	10	illnesses	illness	NNS
cord-017161-lcqrd4v0	351	11	have	have	VBP
cord-017161-lcqrd4v0	351	12	additionally	additionally	RB
cord-017161-lcqrd4v0	351	13	been	be	VBN
cord-017161-lcqrd4v0	351	14	reported	report	VBN
cord-017161-lcqrd4v0	351	15	in	in	IN
cord-017161-lcqrd4v0	351	16	association	association	NN
cord-017161-lcqrd4v0	351	17	with	with	IN
cord-017161-lcqrd4v0	351	18	cancers	cancer	NNS
cord-017161-lcqrd4v0	351	19	and	and	CC
cord-017161-lcqrd4v0	351	20	haematological	haematological	JJ
cord-017161-lcqrd4v0	351	21	malignancies	malignancy	NNS
cord-017161-lcqrd4v0	351	22	[	[	-LRB-
cord-017161-lcqrd4v0	351	23	194	194	CD
cord-017161-lcqrd4v0	351	24	,	,	,
cord-017161-lcqrd4v0	351	25	195	195	CD
cord-017161-lcqrd4v0	351	26	]	]	-RRB-
cord-017161-lcqrd4v0	351	27	.	.	.
cord-017161-lcqrd4v0	352	1	However	however	RB
cord-017161-lcqrd4v0	352	2	,	,	,
cord-017161-lcqrd4v0	352	3	associations	association	NNS
cord-017161-lcqrd4v0	352	4	between	between	IN
cord-017161-lcqrd4v0	352	5	PAN	PAN	NNP
cord-017161-lcqrd4v0	352	6	and	and	CC
cord-017161-lcqrd4v0	352	7	these	these	DT
cord-017161-lcqrd4v0	352	8	infections	infection	NNS
cord-017161-lcqrd4v0	352	9	or	or	CC
cord-017161-lcqrd4v0	352	10	other	other	JJ
cord-017161-lcqrd4v0	352	11	conditions	condition	NNS
cord-017161-lcqrd4v0	352	12	are	be	VBP
cord-017161-lcqrd4v0	352	13	rare	rare	JJ
cord-017161-lcqrd4v0	352	14	in	in	IN
cord-017161-lcqrd4v0	352	15	childhood	childhood	NN
cord-017161-lcqrd4v0	352	16	.	.	.
cord-017161-lcqrd4v0	353	1	Streptococcal	streptococcal	JJ
cord-017161-lcqrd4v0	353	2	infection	infection	NN
cord-017161-lcqrd4v0	353	3	may	may	MD
cord-017161-lcqrd4v0	353	4	be	be	VB
cord-017161-lcqrd4v0	353	5	an	an	DT
cord-017161-lcqrd4v0	353	6	important	important	JJ
cord-017161-lcqrd4v0	353	7	trigger	trigger	NN
cord-017161-lcqrd4v0	353	8	[	[	-LRB-
cord-017161-lcqrd4v0	353	9	195	195	CD
cord-017161-lcqrd4v0	353	10	]	]	-RRB-
cord-017161-lcqrd4v0	353	11	,	,	,
cord-017161-lcqrd4v0	353	12	and	and	CC
cord-017161-lcqrd4v0	353	13	indirect	indirect	JJ
cord-017161-lcqrd4v0	353	14	evidence	evidence	NN
cord-017161-lcqrd4v0	353	15	suggests	suggest	VBZ
cord-017161-lcqrd4v0	353	16	that	that	IN
cord-017161-lcqrd4v0	353	17	bacterial	bacterial	JJ
cord-017161-lcqrd4v0	353	18	SAgs	SAgs	NNP
cord-017161-lcqrd4v0	353	19	may	may	MD
cord-017161-lcqrd4v0	353	20	play	play	VB
cord-017161-lcqrd4v0	353	21	a	a	DT
cord-017161-lcqrd4v0	353	22	role	role	NN
cord-017161-lcqrd4v0	353	23	in	in	IN
cord-017161-lcqrd4v0	353	24	some	some	DT
cord-017161-lcqrd4v0	353	25	cases	case	NNS
cord-017161-lcqrd4v0	353	26	[	[	-LRB-
cord-017161-lcqrd4v0	353	27	56	56	CD
cord-017161-lcqrd4v0	353	28	]	]	-RRB-
cord-017161-lcqrd4v0	353	29	.	.	.
cord-017161-lcqrd4v0	354	1	In	in	IN
cord-017161-lcqrd4v0	354	2	terms	term	NNS
cord-017161-lcqrd4v0	354	3	of	of	IN
cord-017161-lcqrd4v0	354	4	pathogenetic	pathogenetic	JJ
cord-017161-lcqrd4v0	354	5	mechanisms	mechanism	NNS
cord-017161-lcqrd4v0	354	6	,	,	,
cord-017161-lcqrd4v0	354	7	it	-PRON-	PRP
cord-017161-lcqrd4v0	354	8	seems	seem	VBZ
cord-017161-lcqrd4v0	354	9	likely	likely	JJ
cord-017161-lcqrd4v0	354	10	that	that	IN
cord-017161-lcqrd4v0	354	11	the	the	DT
cord-017161-lcqrd4v0	354	12	immunological	immunological	JJ
cord-017161-lcqrd4v0	354	13	processes	process	NNS
cord-017161-lcqrd4v0	354	14	involved	involve	VBN
cord-017161-lcqrd4v0	354	15	are	be	VBP
cord-017161-lcqrd4v0	354	16	similar	similar	JJ
cord-017161-lcqrd4v0	354	17	to	to	IN
cord-017161-lcqrd4v0	354	18	those	those	DT
cord-017161-lcqrd4v0	354	19	in	in	IN
cord-017161-lcqrd4v0	354	20	other	other	JJ
cord-017161-lcqrd4v0	354	21	systemic	systemic	JJ
cord-017161-lcqrd4v0	354	22	vasculitides	vasculitide	NNS
cord-017161-lcqrd4v0	354	23	and	and	CC
cord-017161-lcqrd4v0	354	24	include	include	VBP
cord-017161-lcqrd4v0	354	25	immune	immune	JJ
cord-017161-lcqrd4v0	354	26	complexes	complex	NNS
cord-017161-lcqrd4v0	354	27	,	,	,
cord-017161-lcqrd4v0	354	28	complement	complement	NN
cord-017161-lcqrd4v0	354	29	,	,	,
cord-017161-lcqrd4v0	354	30	possibly	possibly	RB
cord-017161-lcqrd4v0	354	31	autoantibodies	autoantibody	NNS
cord-017161-lcqrd4v0	354	32	,	,	,
cord-017161-lcqrd4v0	354	33	cell	cell	NN
cord-017161-lcqrd4v0	354	34	adhesion	adhesion	NN
cord-017161-lcqrd4v0	354	35	molecules	molecule	NNS
cord-017161-lcqrd4v0	354	36	,	,	,
cord-017161-lcqrd4v0	354	37	cytokines	cytokine	NNS
cord-017161-lcqrd4v0	354	38	,	,	,
cord-017161-lcqrd4v0	354	39	growth	growth	NN
cord-017161-lcqrd4v0	354	40	factors	factor	NNS
cord-017161-lcqrd4v0	354	41	,	,	,
cord-017161-lcqrd4v0	354	42	chemokines	chemokine	NNS
cord-017161-lcqrd4v0	354	43	,	,	,
cord-017161-lcqrd4v0	354	44	neutrophils	neutrophil	NNS
cord-017161-lcqrd4v0	354	45	and	and	CC
cord-017161-lcqrd4v0	354	46	T	t	NN
cord-017161-lcqrd4v0	354	47	cells	cell	NNS
cord-017161-lcqrd4v0	354	48	[	[	-LRB-
cord-017161-lcqrd4v0	354	49	196	196	CD
cord-017161-lcqrd4v0	354	50	,	,	,
cord-017161-lcqrd4v0	354	51	197	197	CD
cord-017161-lcqrd4v0	354	52	]	]	-RRB-
cord-017161-lcqrd4v0	354	53	.	.	.
cord-017161-lcqrd4v0	355	1	Of	of	IN
cord-017161-lcqrd4v0	355	2	note	note	VB
cord-017161-lcqrd4v0	355	3	,	,	,
cord-017161-lcqrd4v0	355	4	immunohistochemical	immunohistochemical	JJ
cord-017161-lcqrd4v0	355	5	studies	study	NNS
cord-017161-lcqrd4v0	355	6	performed	perform	VBN
cord-017161-lcqrd4v0	355	7	on	on	IN
cord-017161-lcqrd4v0	355	8	biopsied	biopsie	VBN
cord-017161-lcqrd4v0	355	9	perineural	perineural	JJ
cord-017161-lcqrd4v0	355	10	and	and	CC
cord-017161-lcqrd4v0	355	11	muscle	muscle	NN
cord-017161-lcqrd4v0	355	12	vessels	vessel	NNS
cord-017161-lcqrd4v0	355	13	from	from	IN
cord-017161-lcqrd4v0	355	14	homogeneous	homogeneous	JJ
cord-017161-lcqrd4v0	355	15	populations	population	NNS
cord-017161-lcqrd4v0	355	16	of	of	IN
cord-017161-lcqrd4v0	355	17	PAN	PAN	NNP
cord-017161-lcqrd4v0	355	18	patients	patient	NNS
cord-017161-lcqrd4v0	355	19	showed	show	VBD
cord-017161-lcqrd4v0	355	20	that	that	IN
cord-017161-lcqrd4v0	355	21	in	in	IN
cord-017161-lcqrd4v0	355	22	fl	fl	NNP
cord-017161-lcqrd4v0	355	23	ammatory	ammatory	NNP
cord-017161-lcqrd4v0	355	24	in	in	IN
cord-017161-lcqrd4v0	355	25	fi	fi	NNP
cord-017161-lcqrd4v0	355	26	ltrates	ltrates	NNP
cord-017161-lcqrd4v0	355	27	consist	consist	VBP
cord-017161-lcqrd4v0	355	28	mainly	mainly	RB
cord-017161-lcqrd4v0	355	29	of	of	IN
cord-017161-lcqrd4v0	355	30	macrophages	macrophage	NNS
cord-017161-lcqrd4v0	355	31	and	and	CC
cord-017161-lcqrd4v0	355	32	T	t	NN
cord-017161-lcqrd4v0	355	33	lymphocytes	lymphocyte	NNS
cord-017161-lcqrd4v0	355	34	,	,	,
cord-017161-lcqrd4v0	355	35	particularly	particularly	RB
cord-017161-lcqrd4v0	355	36	of	of	IN
cord-017161-lcqrd4v0	355	37	the	the	DT
cord-017161-lcqrd4v0	355	38	CD8	CD8	NNP
cord-017161-lcqrd4v0	355	39	+	+	CC
cord-017161-lcqrd4v0	355	40	subset	subset	VBN
cord-017161-lcqrd4v0	355	41	[	[	-LRB-
cord-017161-lcqrd4v0	355	42	198	198	CD
cord-017161-lcqrd4v0	355	43	]	]	-RRB-
cord-017161-lcqrd4v0	355	44	.	.	.
cord-017161-lcqrd4v0	356	1	To	to	IN
cord-017161-lcqrd4v0	356	2	date	date	NN
cord-017161-lcqrd4v0	356	3	,	,	,
cord-017161-lcqrd4v0	356	4	there	there	EX
cord-017161-lcqrd4v0	356	5	is	be	VBZ
cord-017161-lcqrd4v0	356	6	no	no	DT
cord-017161-lcqrd4v0	356	7	reliable	reliable	JJ
cord-017161-lcqrd4v0	356	8	animal	animal	NN
cord-017161-lcqrd4v0	356	9	model	model	NN
cord-017161-lcqrd4v0	356	10	of	of	IN
cord-017161-lcqrd4v0	356	11	the	the	DT
cord-017161-lcqrd4v0	356	12	disease	disease	NN
cord-017161-lcqrd4v0	356	13	.	.	.
cord-017161-lcqrd4v0	357	1	The	the	DT
cord-017161-lcqrd4v0	357	2	PAN	pan	NN
cord-017161-lcqrd4v0	357	3	-	-	HYPH
cord-017161-lcqrd4v0	357	4	like	like	JJ
cord-017161-lcqrd4v0	357	5	disease	disease	NN
cord-017161-lcqrd4v0	357	6	in	in	IN
cord-017161-lcqrd4v0	357	7	cynomolgus	cynomolgus	JJ
cord-017161-lcqrd4v0	357	8	macaques	macaque	NNS
cord-017161-lcqrd4v0	357	9	,	,	,
cord-017161-lcqrd4v0	357	10	which	which	WDT
cord-017161-lcqrd4v0	357	11	is	be	VBZ
cord-017161-lcqrd4v0	357	12	very	very	RB
cord-017161-lcqrd4v0	357	13	similar	similar	JJ
cord-017161-lcqrd4v0	357	14	to	to	IN
cord-017161-lcqrd4v0	357	15	the	the	DT
cord-017161-lcqrd4v0	357	16	human	human	JJ
cord-017161-lcqrd4v0	357	17	disease	disease	NN
cord-017161-lcqrd4v0	357	18	,	,	,
cord-017161-lcqrd4v0	357	19	occurs	occur	VBZ
cord-017161-lcqrd4v0	357	20	only	only	RB
cord-017161-lcqrd4v0	357	21	sporadically	sporadically	RB
cord-017161-lcqrd4v0	357	22	[	[	-LRB-
cord-017161-lcqrd4v0	357	23	199	199	CD
cord-017161-lcqrd4v0	357	24	,	,	,
cord-017161-lcqrd4v0	357	25	200	200	CD
cord-017161-lcqrd4v0	357	26	]	]	-RRB-
cord-017161-lcqrd4v0	357	27	.	.	.
cord-017161-lcqrd4v0	358	1	Snyder	Snyder	NNP
cord-017161-lcqrd4v0	358	2	et	et	NNP
cord-017161-lcqrd4v0	358	3	al	al	NNP
cord-017161-lcqrd4v0	358	4	.	.	.
cord-017161-lcqrd4v0	359	1	described	describe	VBD
cord-017161-lcqrd4v0	359	2	a	a	DT
cord-017161-lcqrd4v0	359	3	PAN	pan	NN
cord-017161-lcqrd4v0	359	4	-	-	HYPH
cord-017161-lcqrd4v0	359	5	like	like	JJ
cord-017161-lcqrd4v0	359	6	illness	illness	NN
cord-017161-lcqrd4v0	359	7	arising	arise	VBG
cord-017161-lcqrd4v0	359	8	spontaneously	spontaneously	RB
cord-017161-lcqrd4v0	359	9	in	in	IN
cord-017161-lcqrd4v0	359	10	beagle	beagle	NN
cord-017161-lcqrd4v0	359	11	dogs	dog	NNS
cord-017161-lcqrd4v0	359	12	,	,	,
cord-017161-lcqrd4v0	359	13	but	but	CC
cord-017161-lcqrd4v0	359	14	to	to	IN
cord-017161-lcqrd4v0	359	15	date	date	NN
cord-017161-lcqrd4v0	359	16	this	this	DT
cord-017161-lcqrd4v0	359	17	animal	animal	NN
cord-017161-lcqrd4v0	359	18	model	model	NN
cord-017161-lcqrd4v0	359	19	has	have	VBZ
cord-017161-lcqrd4v0	359	20	not	not	RB
cord-017161-lcqrd4v0	359	21	provided	provide	VBN
cord-017161-lcqrd4v0	359	22	insight	insight	NN
cord-017161-lcqrd4v0	359	23	to	to	IN
cord-017161-lcqrd4v0	359	24	the	the	DT
cord-017161-lcqrd4v0	359	25	pathogenesis	pathogenesis	NN
cord-017161-lcqrd4v0	359	26	of	of	IN
cord-017161-lcqrd4v0	359	27	PAN	PAN	NNP
cord-017161-lcqrd4v0	359	28	in	in	IN
cord-017161-lcqrd4v0	359	29	humans	human	NNS
cord-017161-lcqrd4v0	359	30	[	[	-LRB-
cord-017161-lcqrd4v0	359	31	201	201	CD
cord-017161-lcqrd4v0	359	32	]	]	-RRB-
cord-017161-lcqrd4v0	359	33	.	.	.
cord-017161-lcqrd4v0	360	1	Furthermore	furthermore	RB
cord-017161-lcqrd4v0	360	2	,	,	,
cord-017161-lcqrd4v0	360	3	it	-PRON-	PRP
cord-017161-lcqrd4v0	360	4	is	be	VBZ
cord-017161-lcqrd4v0	360	5	assumed	assume	VBN
cord-017161-lcqrd4v0	360	6	that	that	IN
cord-017161-lcqrd4v0	360	7	there	there	EX
cord-017161-lcqrd4v0	360	8	are	be	VBP
cord-017161-lcqrd4v0	360	9	probably	probably	RB
cord-017161-lcqrd4v0	360	10	genetic	genetic	JJ
cord-017161-lcqrd4v0	360	11	predisposing	predisposing	JJ
cord-017161-lcqrd4v0	360	12	factors	factor	NNS
cord-017161-lcqrd4v0	360	13	that	that	WDT
cord-017161-lcqrd4v0	360	14	may	may	MD
cord-017161-lcqrd4v0	360	15	make	make	VB
cord-017161-lcqrd4v0	360	16	individuals	individual	NNS
cord-017161-lcqrd4v0	360	17	vulnerable	vulnerable	JJ
cord-017161-lcqrd4v0	360	18	to	to	TO
cord-017161-lcqrd4v0	360	19	develop	develop	VB
cord-017161-lcqrd4v0	360	20	PAN	PAN	NNP
cord-017161-lcqrd4v0	360	21	,	,	,
cord-017161-lcqrd4v0	360	22	as	as	IN
cord-017161-lcqrd4v0	360	23	have	have	VBP
cord-017161-lcqrd4v0	360	24	also	also	RB
cord-017161-lcqrd4v0	360	25	been	be	VBN
cord-017161-lcqrd4v0	360	26	considered	consider	VBN
cord-017161-lcqrd4v0	360	27	for	for	IN
cord-017161-lcqrd4v0	360	28	other	other	JJ
cord-017161-lcqrd4v0	360	29	vasculitides	vasculitide	NNS
cord-017161-lcqrd4v0	360	30	[	[	-LRB-
cord-017161-lcqrd4v0	360	31	202	202	CD
cord-017161-lcqrd4v0	360	32	]	]	-RRB-
cord-017161-lcqrd4v0	360	33	[	[	-LRB-
cord-017161-lcqrd4v0	360	34	203	203	CD
cord-017161-lcqrd4v0	360	35	]	]	-RRB-
cord-017161-lcqrd4v0	360	36	[	[	-LRB-
cord-017161-lcqrd4v0	360	37	204	204	CD
cord-017161-lcqrd4v0	360	38	]	]	-RRB-
cord-017161-lcqrd4v0	360	39	.	.	.
cord-017161-lcqrd4v0	361	1	An	an	DT
cord-017161-lcqrd4v0	361	2	example	example	NN
cord-017161-lcqrd4v0	361	3	of	of	IN
cord-017161-lcqrd4v0	361	4	this	this	DT
cord-017161-lcqrd4v0	361	5	is	be	VBZ
cord-017161-lcqrd4v0	361	6	the	the	DT
cord-017161-lcqrd4v0	361	7	link	link	NN
cord-017161-lcqrd4v0	361	8	with	with	IN
cord-017161-lcqrd4v0	361	9	familial	familial	JJ
cord-017161-lcqrd4v0	361	10	Mediterranean	mediterranean	JJ
cord-017161-lcqrd4v0	361	11	fever	fever	NN
cord-017161-lcqrd4v0	361	12	[	[	-LRB-
cord-017161-lcqrd4v0	361	13	56	56	CD
cord-017161-lcqrd4v0	361	14	,	,	,
cord-017161-lcqrd4v0	361	15	205	205	CD
cord-017161-lcqrd4v0	361	16	]	]	-RRB-
cord-017161-lcqrd4v0	361	17	.	.	.
cord-017161-lcqrd4v0	362	1	Yalcinkaya	Yalcinkaya	NNP
cord-017161-lcqrd4v0	362	2	et	et	NNP
cord-017161-lcqrd4v0	362	3	al	al	NNP
cord-017161-lcqrd4v0	362	4	.	.	NNP
cord-017161-lcqrd4v0	362	5	have	have	VBP
cord-017161-lcqrd4v0	362	6	recently	recently	RB
cord-017161-lcqrd4v0	362	7	reported	report	VBN
cord-017161-lcqrd4v0	362	8	on	on	IN
cord-017161-lcqrd4v0	362	9	the	the	DT
cord-017161-lcqrd4v0	362	10	prevalence	prevalence	NN
cord-017161-lcqrd4v0	362	11	of	of	IN
cord-017161-lcqrd4v0	362	12	FMF	FMF	NNP
cord-017161-lcqrd4v0	362	13	mutations	mutation	NNS
cord-017161-lcqrd4v0	362	14	in	in	IN
cord-017161-lcqrd4v0	362	15	29	29	CD
cord-017161-lcqrd4v0	362	16	children	child	NNS
cord-017161-lcqrd4v0	362	17	with	with	IN
cord-017161-lcqrd4v0	362	18	PAN	PAN	NNP
cord-017161-lcqrd4v0	362	19	showing	show	VBG
cord-017161-lcqrd4v0	362	20	that	that	IN
cord-017161-lcqrd4v0	362	21	38	38	CD
cord-017161-lcqrd4v0	362	22	%	%	NN
cord-017161-lcqrd4v0	362	23	of	of	IN
cord-017161-lcqrd4v0	362	24	the	the	DT
cord-017161-lcqrd4v0	362	25	patients	patient	NNS
cord-017161-lcqrd4v0	362	26	were	be	VBD
cord-017161-lcqrd4v0	362	27	carriers	carrier	NNS
cord-017161-lcqrd4v0	362	28	of	of	IN
cord-017161-lcqrd4v0	362	29	MEFV	MEFV	NNP
cord-017161-lcqrd4v0	362	30	mutations	mutation	NNS
cord-017161-lcqrd4v0	362	31	[	[	-LRB-
cord-017161-lcqrd4v0	362	32	205	205	CD
cord-017161-lcqrd4v0	362	33	]	]	-RRB-
cord-017161-lcqrd4v0	362	34	.	.	.
cord-017161-lcqrd4v0	363	1	The	the	DT
cord-017161-lcqrd4v0	363	2	new	new	JJ
cord-017161-lcqrd4v0	363	3	EULAR	EULAR	NNP
cord-017161-lcqrd4v0	363	4	/	/	SYM
cord-017161-lcqrd4v0	363	5	PRINTO	PRINTO	NNP
cord-017161-lcqrd4v0	363	6	/	/	SYM
cord-017161-lcqrd4v0	363	7	PRES	PRES	NNP
cord-017161-lcqrd4v0	363	8	classi	classi	FW
cord-017161-lcqrd4v0	363	9	fi	fi	NNP
cord-017161-lcqrd4v0	363	10	cation	cation	NN
cord-017161-lcqrd4v0	363	11	criteria	criterion	NNS
cord-017161-lcqrd4v0	363	12	for	for	IN
cord-017161-lcqrd4v0	363	13	PAN	PAN	NNP
cord-017161-lcqrd4v0	363	14	are	be	VBP
cord-017161-lcqrd4v0	363	15	as	as	IN
cord-017161-lcqrd4v0	363	16	follows	follow	VBZ
cord-017161-lcqrd4v0	363	17	:	:	:
cord-017161-lcqrd4v0	364	1	histopathological	histopathological	JJ
cord-017161-lcqrd4v0	364	2	evidence	evidence	NN
cord-017161-lcqrd4v0	364	3	of	of	IN
cord-017161-lcqrd4v0	364	4	necrotizing	necrotize	VBG
cord-017161-lcqrd4v0	364	5	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	364	6	in	in	IN
cord-017161-lcqrd4v0	364	7	medium	medium	NN
cord-017161-lcqrd4v0	364	8	-	-	HYPH
cord-017161-lcqrd4v0	364	9	or	or	CC
cord-017161-lcqrd4v0	364	10	small	small	JJ
cord-017161-lcqrd4v0	364	11	-	-	HYPH
cord-017161-lcqrd4v0	364	12	sized	sized	JJ
cord-017161-lcqrd4v0	364	13	arteries	artery	NNS
cord-017161-lcqrd4v0	364	14	or	or	CC
cord-017161-lcqrd4v0	364	15	angiographic	angiographic	JJ
cord-017161-lcqrd4v0	364	16	abnormality	abnormality	NN
cord-017161-lcqrd4v0	364	17	(	(	-LRB-
cord-017161-lcqrd4v0	364	18	aneurysm	aneurysm	NN
cord-017161-lcqrd4v0	364	19	,	,	,
cord-017161-lcqrd4v0	364	20	stenosis	stenosis	NN
cord-017161-lcqrd4v0	364	21	or	or	CC
cord-017161-lcqrd4v0	364	22	occlusion	occlusion	NN
cord-017161-lcqrd4v0	364	23	)	)	-RRB-
cord-017161-lcqrd4v0	364	24	as	as	IN
cord-017161-lcqrd4v0	364	25	a	a	DT
cord-017161-lcqrd4v0	364	26	mandatory	mandatory	JJ
cord-017161-lcqrd4v0	364	27	criterion	criterion	NN
cord-017161-lcqrd4v0	364	28	,	,	,
cord-017161-lcqrd4v0	364	29	plus	plus	CC
cord-017161-lcqrd4v0	364	30	one	one	CD
cord-017161-lcqrd4v0	364	31	of	of	IN
cord-017161-lcqrd4v0	364	32	the	the	DT
cord-017161-lcqrd4v0	364	33	following	follow	VBG
cord-017161-lcqrd4v0	364	34	fi	fi	NNP
cord-017161-lcqrd4v0	364	35	ve	ve	JJ
cord-017161-lcqrd4v0	364	36	-	-	HYPH
cord-017161-lcqrd4v0	364	37	skin	skin	NN
cord-017161-lcqrd4v0	364	38	involvement	involvement	NN
cord-017161-lcqrd4v0	364	39	,	,	,
cord-017161-lcqrd4v0	364	40	myalgia	myalgia	NN
cord-017161-lcqrd4v0	364	41	or	or	CC
cord-017161-lcqrd4v0	364	42	muscle	muscle	NN
cord-017161-lcqrd4v0	364	43	tenderness	tenderness	NN
cord-017161-lcqrd4v0	364	44	,	,	,
cord-017161-lcqrd4v0	364	45	hypertension	hypertension	NN
cord-017161-lcqrd4v0	364	46	,	,	,
cord-017161-lcqrd4v0	364	47	peripheral	peripheral	JJ
cord-017161-lcqrd4v0	364	48	neuropathy	neuropathy	NN
cord-017161-lcqrd4v0	364	49	and	and	CC
cord-017161-lcqrd4v0	364	50	renal	renal	JJ
cord-017161-lcqrd4v0	364	51	involvement	involvement	NN
cord-017161-lcqrd4v0	364	52	[	[	-LRB-
cord-017161-lcqrd4v0	364	53	8	8	CD
cord-017161-lcqrd4v0	364	54	]	]	-RRB-
cord-017161-lcqrd4v0	364	55	.	.	.
cord-017161-lcqrd4v0	365	1	The	the	DT
cord-017161-lcqrd4v0	365	2	main	main	JJ
cord-017161-lcqrd4v0	365	3	clinical	clinical	JJ
cord-017161-lcqrd4v0	365	4	features	feature	NNS
cord-017161-lcqrd4v0	365	5	of	of	IN
cord-017161-lcqrd4v0	365	6	PAN	PAN	NNP
cord-017161-lcqrd4v0	365	7	are	be	VBP
cord-017161-lcqrd4v0	365	8	malaise	malaise	NN
cord-017161-lcqrd4v0	365	9	,	,	,
cord-017161-lcqrd4v0	365	10	fever	fever	NN
cord-017161-lcqrd4v0	365	11	,	,	,
cord-017161-lcqrd4v0	365	12	weight	weight	NN
cord-017161-lcqrd4v0	365	13	loss	loss	NN
cord-017161-lcqrd4v0	365	14	,	,	,
cord-017161-lcqrd4v0	365	15	skin	skin	NN
cord-017161-lcqrd4v0	365	16	rash	rash	NN
cord-017161-lcqrd4v0	365	17	,	,	,
cord-017161-lcqrd4v0	365	18	myalgia	myalgia	NN
cord-017161-lcqrd4v0	365	19	,	,	,
cord-017161-lcqrd4v0	365	20	abdominal	abdominal	JJ
cord-017161-lcqrd4v0	365	21	pain	pain	NN
cord-017161-lcqrd4v0	365	22	and	and	CC
cord-017161-lcqrd4v0	365	23	arthropathy	arthropathy	NN
cord-017161-lcqrd4v0	365	24	[	[	-LRB-
cord-017161-lcqrd4v0	365	25	56	56	CD
cord-017161-lcqrd4v0	365	26	]	]	-RRB-
cord-017161-lcqrd4v0	365	27	.	.	.
cord-017161-lcqrd4v0	366	1	Additional	additional	JJ
cord-017161-lcqrd4v0	366	2	features	feature	NNS
cord-017161-lcqrd4v0	366	3	include	include	VBP
cord-017161-lcqrd4v0	366	4	ischemic	ischemic	JJ
cord-017161-lcqrd4v0	366	5	heart	heart	NN
cord-017161-lcqrd4v0	366	6	and	and	CC
cord-017161-lcqrd4v0	366	7	testicular	testicular	JJ
cord-017161-lcqrd4v0	366	8	pain	pain	NN
cord-017161-lcqrd4v0	366	9	;	;	:
cord-017161-lcqrd4v0	366	10	renal	renal	JJ
cord-017161-lcqrd4v0	366	11	manifestations	manifestation	NNS
cord-017161-lcqrd4v0	366	12	such	such	JJ
cord-017161-lcqrd4v0	366	13	as	as	IN
cord-017161-lcqrd4v0	366	14	haematuria	haematuria	NNP
cord-017161-lcqrd4v0	366	15	,	,	,
cord-017161-lcqrd4v0	366	16	proteinuria	proteinuria	NN
cord-017161-lcqrd4v0	366	17	and	and	CC
cord-017161-lcqrd4v0	366	18	hypertension	hypertension	NN
cord-017161-lcqrd4v0	366	19	;	;	:
cord-017161-lcqrd4v0	366	20	and	and	CC
cord-017161-lcqrd4v0	366	21	neurologic	neurologic	JJ
cord-017161-lcqrd4v0	366	22	features	feature	NNS
cord-017161-lcqrd4v0	366	23	such	such	JJ
cord-017161-lcqrd4v0	366	24	as	as	IN
cord-017161-lcqrd4v0	366	25	focal	focal	JJ
cord-017161-lcqrd4v0	366	26	defects	defect	NNS
cord-017161-lcqrd4v0	366	27	,	,	,
cord-017161-lcqrd4v0	366	28	haemiplegia	haemiplegia	NNP
cord-017161-lcqrd4v0	366	29	,	,	,
cord-017161-lcqrd4v0	366	30	visual	visual	JJ
cord-017161-lcqrd4v0	366	31	loss	loss	NN
cord-017161-lcqrd4v0	366	32	,	,	,
cord-017161-lcqrd4v0	366	33	mononeuritis	mononeuritis	NN
cord-017161-lcqrd4v0	366	34	multiplex	multiplex	NN
cord-017161-lcqrd4v0	366	35	and	and	CC
cord-017161-lcqrd4v0	366	36	organic	organic	JJ
cord-017161-lcqrd4v0	366	37	psychosis	psychosis	NN
cord-017161-lcqrd4v0	366	38	.	.	.
cord-017161-lcqrd4v0	367	1	Livido	Livido	NNP
cord-017161-lcqrd4v0	367	2	reticularis	reticularis	NNPS
cord-017161-lcqrd4v0	367	3	is	be	VBZ
cord-017161-lcqrd4v0	367	4	also	also	RB
cord-017161-lcqrd4v0	367	5	a	a	DT
cord-017161-lcqrd4v0	367	6	characteristic	characteristic	JJ
cord-017161-lcqrd4v0	367	7	feature	feature	NN
cord-017161-lcqrd4v0	367	8	,	,	,
cord-017161-lcqrd4v0	367	9	and	and	CC
cord-017161-lcqrd4v0	367	10	occasionally	occasionally	RB
cord-017161-lcqrd4v0	367	11	subcutaneous	subcutaneous	JJ
cord-017161-lcqrd4v0	367	12	nodules	nodule	NNS
cord-017161-lcqrd4v0	367	13	overlying	overlie	VBG
cord-017161-lcqrd4v0	367	14	affected	affected	JJ
cord-017161-lcqrd4v0	367	15	arteries	artery	NNS
cord-017161-lcqrd4v0	367	16	are	be	VBP
cord-017161-lcqrd4v0	367	17	present	present	JJ
cord-017161-lcqrd4v0	367	18	.	.	.
cord-017161-lcqrd4v0	368	1	For	for	IN
cord-017161-lcqrd4v0	368	2	many	many	JJ
cord-017161-lcqrd4v0	368	3	years	year	NNS
cord-017161-lcqrd4v0	368	4	,	,	,
cord-017161-lcqrd4v0	368	5	the	the	DT
cord-017161-lcqrd4v0	368	6	treatment	treatment	NN
cord-017161-lcqrd4v0	368	7	of	of	IN
cord-017161-lcqrd4v0	368	8	PAN	PAN	NNP
cord-017161-lcqrd4v0	368	9	has	have	VBZ
cord-017161-lcqrd4v0	368	10	involved	involve	VBN
cord-017161-lcqrd4v0	368	11	the	the	DT
cord-017161-lcqrd4v0	368	12	administration	administration	NN
cord-017161-lcqrd4v0	368	13	of	of	IN
cord-017161-lcqrd4v0	368	14	high	high	JJ
cord-017161-lcqrd4v0	368	15	-	-	HYPH
cord-017161-lcqrd4v0	368	16	dose	dose	NN
cord-017161-lcqrd4v0	368	17	steroid	steroid	NN
cord-017161-lcqrd4v0	368	18	with	with	IN
cord-017161-lcqrd4v0	368	19	an	an	DT
cord-017161-lcqrd4v0	368	20	additional	additional	JJ
cord-017161-lcqrd4v0	368	21	cytotoxic	cytotoxic	JJ
cord-017161-lcqrd4v0	368	22	agent	agent	NN
cord-017161-lcqrd4v0	368	23	such	such	JJ
cord-017161-lcqrd4v0	368	24	as	as	IN
cord-017161-lcqrd4v0	368	25	cyclophosphamide	cyclophosphamide	NN
cord-017161-lcqrd4v0	368	26	to	to	TO
cord-017161-lcqrd4v0	368	27	induce	induce	VB
cord-017161-lcqrd4v0	368	28	remission	remission	NN
cord-017161-lcqrd4v0	368	29	[	[	-LRB-
cord-017161-lcqrd4v0	368	30	56	56	CD
cord-017161-lcqrd4v0	368	31	,	,	,
cord-017161-lcqrd4v0	368	32	[	[	-LRB-
cord-017161-lcqrd4v0	368	33	206	206	CD
cord-017161-lcqrd4v0	368	34	]	]	-RRB-
cord-017161-lcqrd4v0	368	35	[	[	-LRB-
cord-017161-lcqrd4v0	368	36	207	207	CD
cord-017161-lcqrd4v0	368	37	]	]	-RRB-
cord-017161-lcqrd4v0	368	38	[	[	-LRB-
cord-017161-lcqrd4v0	368	39	208	208	CD
cord-017161-lcqrd4v0	368	40	]	]	-RRB-
cord-017161-lcqrd4v0	368	41	.	.	.
cord-017161-lcqrd4v0	369	1	Empirically	empirically	RB
cord-017161-lcqrd4v0	369	2	,	,	,
cord-017161-lcqrd4v0	369	3	aspirin	aspirin	NN
cord-017161-lcqrd4v0	369	4	has	have	VBZ
cord-017161-lcqrd4v0	369	5	also	also	RB
cord-017161-lcqrd4v0	369	6	been	be	VBN
cord-017161-lcqrd4v0	369	7	given	give	VBN
cord-017161-lcqrd4v0	369	8	as	as	IN
cord-017161-lcqrd4v0	369	9	an	an	DT
cord-017161-lcqrd4v0	369	10	anti	anti	JJ
cord-017161-lcqrd4v0	369	11	-	-	JJ
cord-017161-lcqrd4v0	369	12	platelet	platelet	JJ
cord-017161-lcqrd4v0	369	13	agent	agent	NN
cord-017161-lcqrd4v0	369	14	by	by	IN
cord-017161-lcqrd4v0	369	15	some	some	DT
cord-017161-lcqrd4v0	369	16	clinicians	clinician	NNS
cord-017161-lcqrd4v0	369	17	[	[	-LRB-
cord-017161-lcqrd4v0	369	18	209	209	CD
cord-017161-lcqrd4v0	369	19	]	]	-RRB-
cord-017161-lcqrd4v0	369	20	.	.	.
cord-017161-lcqrd4v0	370	1	Once	once	IN
cord-017161-lcqrd4v0	370	2	remission	remission	NN
cord-017161-lcqrd4v0	370	3	is	be	VBZ
cord-017161-lcqrd4v0	370	4	achieved	achieve	VBN
cord-017161-lcqrd4v0	370	5	maintenance	maintenance	NN
cord-017161-lcqrd4v0	370	6	therapy	therapy	NN
cord-017161-lcqrd4v0	370	7	with	with	IN
cord-017161-lcqrd4v0	370	8	daily	daily	JJ
cord-017161-lcqrd4v0	370	9	or	or	CC
cord-017161-lcqrd4v0	370	10	alternate	alternate	JJ
cord-017161-lcqrd4v0	370	11	day	day	NN
cord-017161-lcqrd4v0	370	12	prednisolone	prednisolone	NN
cord-017161-lcqrd4v0	370	13	and	and	CC
cord-017161-lcqrd4v0	370	14	oral	oral	JJ
cord-017161-lcqrd4v0	370	15	azathioprine	azathioprine	NN
cord-017161-lcqrd4v0	370	16	is	be	VBZ
cord-017161-lcqrd4v0	370	17	frequently	frequently	RB
cord-017161-lcqrd4v0	370	18	utilized	utilize	VBN
cord-017161-lcqrd4v0	370	19	for	for	IN
cord-017161-lcqrd4v0	370	20	about	about	RB
cord-017161-lcqrd4v0	370	21	18	18	CD
cord-017161-lcqrd4v0	370	22	months	month	NNS
cord-017161-lcqrd4v0	370	23	.	.	.
cord-017161-lcqrd4v0	371	1	Adjunctive	Adjunctive	NNP
cord-017161-lcqrd4v0	371	2	plasma	plasma	NN
cord-017161-lcqrd4v0	371	3	exchange	exchange	NN
cord-017161-lcqrd4v0	371	4	can	can	MD
cord-017161-lcqrd4v0	371	5	be	be	VB
cord-017161-lcqrd4v0	371	6	used	use	VBN
cord-017161-lcqrd4v0	371	7	in	in	IN
cord-017161-lcqrd4v0	371	8	life	life	NN
cord-017161-lcqrd4v0	371	9	-	-	HYPH
cord-017161-lcqrd4v0	371	10	threatening	threaten	VBG
cord-017161-lcqrd4v0	371	11	situations	situation	NNS
cord-017161-lcqrd4v0	371	12	[	[	-LRB-
cord-017161-lcqrd4v0	371	13	210	210	CD
cord-017161-lcqrd4v0	371	14	]	]	-RRB-
cord-017161-lcqrd4v0	371	15	.	.	.
cord-017161-lcqrd4v0	372	1	Biologic	biologic	JJ
cord-017161-lcqrd4v0	372	2	agents	agent	NNS
cord-017161-lcqrd4v0	372	3	such	such	JJ
cord-017161-lcqrd4v0	372	4	as	as	IN
cord-017161-lcqrd4v0	372	5	in	in	IN
cord-017161-lcqrd4v0	372	6	fl	fl	NNP
cord-017161-lcqrd4v0	372	7	iximab	iximab	NNP
cord-017161-lcqrd4v0	373	1	and	and	CC
cord-017161-lcqrd4v0	373	2	rituximab	rituximab	NN
cord-017161-lcqrd4v0	373	3	are	be	VBP
cord-017161-lcqrd4v0	373	4	increasingly	increasingly	RB
cord-017161-lcqrd4v0	373	5	used	use	VBN
cord-017161-lcqrd4v0	373	6	[	[	-LRB-
cord-017161-lcqrd4v0	373	7	185	185	CD
cord-017161-lcqrd4v0	373	8	,	,	,
cord-017161-lcqrd4v0	373	9	[	[	-LRB-
cord-017161-lcqrd4v0	373	10	211	211	CD
cord-017161-lcqrd4v0	373	11	]	]	-RRB-
cord-017161-lcqrd4v0	373	12	[	[	-LRB-
cord-017161-lcqrd4v0	373	13	212	212	CD
cord-017161-lcqrd4v0	373	14	]	]	-RRB-
cord-017161-lcqrd4v0	373	15	[	[	-LRB-
cord-017161-lcqrd4v0	373	16	213	213	CD
cord-017161-lcqrd4v0	373	17	]	]	-RRB-
cord-017161-lcqrd4v0	373	18	[	[	-LRB-
cord-017161-lcqrd4v0	373	19	214	214	CD
cord-017161-lcqrd4v0	373	20	]	]	-RRB-
cord-017161-lcqrd4v0	373	21	[	[	-LRB-
cord-017161-lcqrd4v0	373	22	215	215	CD
cord-017161-lcqrd4v0	373	23	]	]	-RRB-
cord-017161-lcqrd4v0	373	24	.	.	.
cord-017161-lcqrd4v0	374	1	Treatment	treatment	NN
cord-017161-lcqrd4v0	374	2	for	for	IN
cord-017161-lcqrd4v0	374	3	cutaneous	cutaneous	JJ
cord-017161-lcqrd4v0	374	4	PAN	PAN	NNP
cord-017161-lcqrd4v0	374	5	is	be	VBZ
cord-017161-lcqrd4v0	374	6	typically	typically	RB
cord-017161-lcqrd4v0	374	7	much	much	RB
cord-017161-lcqrd4v0	374	8	less	less	RBR
cord-017161-lcqrd4v0	374	9	aggressive	aggressive	JJ
cord-017161-lcqrd4v0	374	10	.	.	.
cord-017161-lcqrd4v0	375	1	Agents	agent	NNS
cord-017161-lcqrd4v0	375	2	commonly	commonly	RB
cord-017161-lcqrd4v0	375	3	utilized	utilize	VBN
cord-017161-lcqrd4v0	375	4	include	include	VBP
cord-017161-lcqrd4v0	375	5	low	low	JJ
cord-017161-lcqrd4v0	375	6	-	-	HYPH
cord-017161-lcqrd4v0	375	7	dose	dose	NN
cord-017161-lcqrd4v0	375	8	prednisolone	prednisolone	NN
cord-017161-lcqrd4v0	375	9	,	,	,
cord-017161-lcqrd4v0	375	10	anti	anti	JJ
cord-017161-lcqrd4v0	375	11	-	-	JJ
cord-017161-lcqrd4v0	375	12	platelet	platelet	JJ
cord-017161-lcqrd4v0	375	13	agents	agent	NNS
cord-017161-lcqrd4v0	375	14	,	,	,
cord-017161-lcqrd4v0	375	15	colchicine	colchicine	NNP
cord-017161-lcqrd4v0	375	16	,	,	,
cord-017161-lcqrd4v0	375	17	hydroxychloroquine	hydroxychloroquine	NN
cord-017161-lcqrd4v0	375	18	or	or	CC
cord-017161-lcqrd4v0	375	19	azathioprine	azathioprine	NN
cord-017161-lcqrd4v0	375	20	[	[	-LRB-
cord-017161-lcqrd4v0	375	21	56	56	CD
cord-017161-lcqrd4v0	375	22	]	]	-RRB-
cord-017161-lcqrd4v0	375	23	.	.	.
cord-017161-lcqrd4v0	376	1	However	however	RB
cord-017161-lcqrd4v0	376	2	,	,	,
cord-017161-lcqrd4v0	376	3	in	in	IN
cord-017161-lcqrd4v0	376	4	a	a	DT
cord-017161-lcqrd4v0	376	5	few	few	JJ
cord-017161-lcqrd4v0	376	6	cases	case	NNS
cord-017161-lcqrd4v0	376	7	cutaneous	cutaneous	JJ
cord-017161-lcqrd4v0	376	8	PAN	PAN	NNP
cord-017161-lcqrd4v0	376	9	may	may	MD
cord-017161-lcqrd4v0	376	10	progress	progress	VB
cord-017161-lcqrd4v0	376	11	over	over	IN
cord-017161-lcqrd4v0	376	12	time	time	NN
cord-017161-lcqrd4v0	376	13	to	to	IN
cord-017161-lcqrd4v0	376	14	the	the	DT
cord-017161-lcqrd4v0	376	15	systemic	systemic	JJ
cord-017161-lcqrd4v0	376	16	form	form	NN
cord-017161-lcqrd4v0	376	17	of	of	IN
cord-017161-lcqrd4v0	376	18	the	the	DT
cord-017161-lcqrd4v0	376	19	disease	disease	NN
cord-017161-lcqrd4v0	376	20	and	and	CC
cord-017161-lcqrd4v0	376	21	therefore	therefore	RB
cord-017161-lcqrd4v0	376	22	require	require	VBP
cord-017161-lcqrd4v0	376	23	more	more	RBR
cord-017161-lcqrd4v0	376	24	aggressive	aggressive	JJ
cord-017161-lcqrd4v0	376	25	therapy	therapy	NN
cord-017161-lcqrd4v0	376	26	[	[	-LRB-
cord-017161-lcqrd4v0	376	27	56	56	CD
cord-017161-lcqrd4v0	376	28	]	]	-RRB-
cord-017161-lcqrd4v0	376	29	.	.	.
cord-017161-lcqrd4v0	377	1	Ozen	Ozen	NNP
cord-017161-lcqrd4v0	377	2	et	et	FW
cord-017161-lcqrd4v0	377	3	al	al	NNP
cord-017161-lcqrd4v0	377	4	.	.	.
cord-017161-lcqrd4v0	378	1	reported	report	VBN
cord-017161-lcqrd4v0	378	2	on	on	IN
cord-017161-lcqrd4v0	378	3	a	a	DT
cord-017161-lcqrd4v0	378	4	retrospective	retrospective	JJ
cord-017161-lcqrd4v0	378	5	series	series	NN
cord-017161-lcqrd4v0	378	6	of	of	IN
cord-017161-lcqrd4v0	378	7	childhood	childhood	NNP
cord-017161-lcqrd4v0	378	8	PAN	PAN	NNP
cord-017161-lcqrd4v0	378	9	and	and	CC
cord-017161-lcqrd4v0	378	10	improved	improve	VBD
cord-017161-lcqrd4v0	378	11	outcome	outcome	NN
cord-017161-lcqrd4v0	378	12	compared	compare	VBN
cord-017161-lcqrd4v0	378	13	to	to	IN
cord-017161-lcqrd4v0	378	14	that	that	DT
cord-017161-lcqrd4v0	378	15	reported	report	VBN
cord-017161-lcqrd4v0	378	16	in	in	IN
cord-017161-lcqrd4v0	378	17	adults	adult	NNS
cord-017161-lcqrd4v0	378	18	with	with	IN
cord-017161-lcqrd4v0	378	19	only	only	RB
cord-017161-lcqrd4v0	378	20	1	1	CD
cord-017161-lcqrd4v0	378	21	(	(	-LRB-
cord-017161-lcqrd4v0	378	22	1.1	1.1	CD
cord-017161-lcqrd4v0	378	23	%	%	NN
cord-017161-lcqrd4v0	378	24	)	)	-RRB-
cord-017161-lcqrd4v0	378	25	death	death	NN
cord-017161-lcqrd4v0	378	26	and	and	CC
cord-017161-lcqrd4v0	378	27	2	2	CD
cord-017161-lcqrd4v0	378	28	(	(	-LRB-
cord-017161-lcqrd4v0	378	29	2.2	2.2	CD
cord-017161-lcqrd4v0	378	30	%	%	NN
cord-017161-lcqrd4v0	378	31	)	)	-RRB-
cord-017161-lcqrd4v0	378	32	patients	patient	NNS
cord-017161-lcqrd4v0	378	33	with	with	IN
cord-017161-lcqrd4v0	378	34	end	end	NN
cord-017161-lcqrd4v0	378	35	-	-	HYPH
cord-017161-lcqrd4v0	378	36	stage	stage	NN
cord-017161-lcqrd4v0	378	37	renal	renal	JJ
cord-017161-lcqrd4v0	378	38	disease	disease	NN
cord-017161-lcqrd4v0	378	39	among	among	IN
cord-017161-lcqrd4v0	378	40	110	110	CD
cord-017161-lcqrd4v0	378	41	patients	patient	NNS
cord-017161-lcqrd4v0	378	42	[	[	-LRB-
cord-017161-lcqrd4v0	378	43	195	195	CD
cord-017161-lcqrd4v0	378	44	]	]	-RRB-
cord-017161-lcqrd4v0	378	45	.	.	.
cord-017161-lcqrd4v0	379	1	Of	of	IN
cord-017161-lcqrd4v0	379	2	note	note	NN
cord-017161-lcqrd4v0	379	3	,	,	,
cord-017161-lcqrd4v0	379	4	however	however	RB
cord-017161-lcqrd4v0	379	5	,	,	,
cord-017161-lcqrd4v0	379	6	in	in	IN
cord-017161-lcqrd4v0	379	7	that	that	DT
cord-017161-lcqrd4v0	379	8	series	series	NN
cord-017161-lcqrd4v0	379	9	30	30	CD
cord-017161-lcqrd4v0	379	10	%	%	NN
cord-017161-lcqrd4v0	379	11	of	of	IN
cord-017161-lcqrd4v0	379	12	patients	patient	NNS
cord-017161-lcqrd4v0	379	13	were	be	VBD
cord-017161-lcqrd4v0	379	14	classi	classi	NNP
cord-017161-lcqrd4v0	379	15	fi	fi	NNP
cord-017161-lcqrd4v0	379	16	ed	ed	NNP
cord-017161-lcqrd4v0	379	17	as	as	IN
cord-017161-lcqrd4v0	379	18	having	have	VBG
cord-017161-lcqrd4v0	379	19	cutaneous	cutaneous	JJ
cord-017161-lcqrd4v0	379	20	PAN	PAN	NNP
cord-017161-lcqrd4v0	379	21	,	,	,
cord-017161-lcqrd4v0	379	22	which	which	WDT
cord-017161-lcqrd4v0	379	23	typically	typically	RB
cord-017161-lcqrd4v0	379	24	has	have	VBZ
cord-017161-lcqrd4v0	379	25	a	a	DT
cord-017161-lcqrd4v0	379	26	more	more	RBR
cord-017161-lcqrd4v0	379	27	benign	benign	JJ
cord-017161-lcqrd4v0	379	28	course	course	NN
cord-017161-lcqrd4v0	379	29	than	than	IN
cord-017161-lcqrd4v0	379	30	systemic	systemic	JJ
cord-017161-lcqrd4v0	379	31	PAN	PAN	NNP
cord-017161-lcqrd4v0	379	32	[	[	-LRB-
cord-017161-lcqrd4v0	379	33	195	195	CD
cord-017161-lcqrd4v0	379	34	]	]	-RRB-
cord-017161-lcqrd4v0	379	35	.	.	.
cord-017161-lcqrd4v0	380	1	TA	TA	NNP
cord-017161-lcqrd4v0	380	2	is	be	VBZ
cord-017161-lcqrd4v0	380	3	a	a	DT
cord-017161-lcqrd4v0	380	4	predominantly	predominantly	RB
cord-017161-lcqrd4v0	380	5	large	large	JJ
cord-017161-lcqrd4v0	380	6	vessel	vessel	NN
cord-017161-lcqrd4v0	380	7	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	380	8	with	with	IN
cord-017161-lcqrd4v0	380	9	a	a	DT
cord-017161-lcqrd4v0	380	10	worldwide	worldwide	JJ
cord-017161-lcqrd4v0	380	11	distribution	distribution	NN
cord-017161-lcqrd4v0	380	12	,	,	,
cord-017161-lcqrd4v0	380	13	although	although	IN
cord-017161-lcqrd4v0	380	14	the	the	DT
cord-017161-lcqrd4v0	380	15	disease	disease	NN
cord-017161-lcqrd4v0	380	16	is	be	VBZ
cord-017161-lcqrd4v0	380	17	most	most	RBS
cord-017161-lcqrd4v0	380	18	common	common	JJ
cord-017161-lcqrd4v0	380	19	in	in	IN
cord-017161-lcqrd4v0	380	20	Asia	Asia	NNP
cord-017161-lcqrd4v0	380	21	[	[	-LRB-
cord-017161-lcqrd4v0	380	22	216	216	CD
cord-017161-lcqrd4v0	380	23	]	]	-RRB-
cord-017161-lcqrd4v0	380	24	.	.	.
cord-017161-lcqrd4v0	381	1	Onset	onset	NN
cord-017161-lcqrd4v0	381	2	of	of	IN
cord-017161-lcqrd4v0	381	3	TA	TA	NNP
cord-017161-lcqrd4v0	381	4	is	be	VBZ
cord-017161-lcqrd4v0	381	5	most	most	RBS
cord-017161-lcqrd4v0	381	6	common	common	JJ
cord-017161-lcqrd4v0	381	7	during	during	IN
cord-017161-lcqrd4v0	381	8	the	the	DT
cord-017161-lcqrd4v0	381	9	third	third	JJ
cord-017161-lcqrd4v0	381	10	decade	decade	NN
cord-017161-lcqrd4v0	381	11	of	of	IN
cord-017161-lcqrd4v0	381	12	life	life	NN
cord-017161-lcqrd4v0	381	13	but	but	CC
cord-017161-lcqrd4v0	381	14	has	have	VBZ
cord-017161-lcqrd4v0	381	15	been	be	VBN
cord-017161-lcqrd4v0	381	16	well	well	RB
cord-017161-lcqrd4v0	381	17	reported	report	VBN
cord-017161-lcqrd4v0	381	18	in	in	IN
cord-017161-lcqrd4v0	381	19	young	young	JJ
cord-017161-lcqrd4v0	381	20	children	child	NNS
cord-017161-lcqrd4v0	381	21	[	[	-LRB-
cord-017161-lcqrd4v0	381	22	216	216	CD
cord-017161-lcqrd4v0	381	23	]	]	-RRB-
cord-017161-lcqrd4v0	381	24	.	.	.
cord-017161-lcqrd4v0	382	1	Even	even	RB
cord-017161-lcqrd4v0	382	2	though	though	IN
cord-017161-lcqrd4v0	382	3	the	the	DT
cord-017161-lcqrd4v0	382	4	precise	precise	JJ
cord-017161-lcqrd4v0	382	5	factors	factor	NNS
cord-017161-lcqrd4v0	382	6	responsible	responsible	JJ
cord-017161-lcqrd4v0	382	7	for	for	IN
cord-017161-lcqrd4v0	382	8	the	the	DT
cord-017161-lcqrd4v0	382	9	arterial	arterial	JJ
cord-017161-lcqrd4v0	382	10	damage	damage	NN
cord-017161-lcqrd4v0	382	11	in	in	IN
cord-017161-lcqrd4v0	382	12	TA	TA	NNP
cord-017161-lcqrd4v0	382	13	are	be	VBP
cord-017161-lcqrd4v0	382	14	unknown	unknown	JJ
cord-017161-lcqrd4v0	382	15	,	,	,
cord-017161-lcqrd4v0	382	16	it	-PRON-	PRP
cord-017161-lcqrd4v0	382	17	is	be	VBZ
cord-017161-lcqrd4v0	382	18	believed	believe	VBN
cord-017161-lcqrd4v0	382	19	that	that	IN
cord-017161-lcqrd4v0	382	20	genetically	genetically	RB
cord-017161-lcqrd4v0	382	21	linked	link	VBN
cord-017161-lcqrd4v0	382	22	immune	immune	JJ
cord-017161-lcqrd4v0	382	23	responses	response	NNS
cord-017161-lcqrd4v0	382	24	to	to	IN
cord-017161-lcqrd4v0	382	25	unidenti	unidenti	NNP
cord-017161-lcqrd4v0	382	26	fi	fi	NN
cord-017161-lcqrd4v0	382	27	ed	ed	NN
cord-017161-lcqrd4v0	382	28	antigens	antigen	NNS
cord-017161-lcqrd4v0	382	29	may	may	MD
cord-017161-lcqrd4v0	382	30	incite	incite	VB
cord-017161-lcqrd4v0	382	31	autoimmune	autoimmune	JJ
cord-017161-lcqrd4v0	382	32	damage	damage	NN
cord-017161-lcqrd4v0	382	33	by	by	IN
cord-017161-lcqrd4v0	382	34	cell	cell	NN
cord-017161-lcqrd4v0	382	35	-	-	HYPH
cord-017161-lcqrd4v0	382	36	mediated	mediate	VBN
cord-017161-lcqrd4v0	382	37	or	or	CC
cord-017161-lcqrd4v0	382	38	humoral	humoral	JJ
cord-017161-lcqrd4v0	382	39	pathways	pathway	NNS
cord-017161-lcqrd4v0	382	40	,	,	,
cord-017161-lcqrd4v0	382	41	resulting	result	VBG
cord-017161-lcqrd4v0	382	42	in	in	IN
cord-017161-lcqrd4v0	382	43	the	the	DT
cord-017161-lcqrd4v0	382	44	disease	disease	NN
cord-017161-lcqrd4v0	382	45	and	and	CC
cord-017161-lcqrd4v0	382	46	its	-PRON-	PRP$
cord-017161-lcqrd4v0	382	47	relapses	relapse	NNS
cord-017161-lcqrd4v0	382	48	[	[	-LRB-
cord-017161-lcqrd4v0	382	49	216	216	CD
cord-017161-lcqrd4v0	382	50	]	]	-RRB-
cord-017161-lcqrd4v0	382	51	.	.	.
cord-017161-lcqrd4v0	383	1	In	in	IN
cord-017161-lcqrd4v0	383	2	the	the	DT
cord-017161-lcqrd4v0	383	3	acute	acute	JJ
cord-017161-lcqrd4v0	383	4	phase	phase	NN
cord-017161-lcqrd4v0	383	5	of	of	IN
cord-017161-lcqrd4v0	383	6	TA	TA	NNP
cord-017161-lcqrd4v0	383	7	,	,	,
cord-017161-lcqrd4v0	383	8	the	the	DT
cord-017161-lcqrd4v0	383	9	in	in	IN
cord-017161-lcqrd4v0	383	10	fl	fl	NNP
cord-017161-lcqrd4v0	383	11	ammatory	ammatory	NNP
cord-017161-lcqrd4v0	383	12	lesions	lesion	NNS
cord-017161-lcqrd4v0	383	13	originate	originate	VBP
cord-017161-lcqrd4v0	383	14	in	in	IN
cord-017161-lcqrd4v0	383	15	the	the	DT
cord-017161-lcqrd4v0	383	16	vasa	vasa	NNP
cord-017161-lcqrd4v0	383	17	varum	varum	NNP
cord-017161-lcqrd4v0	383	18	and	and	CC
cord-017161-lcqrd4v0	383	19	are	be	VBP
cord-017161-lcqrd4v0	383	20	characterized	characterize	VBN
cord-017161-lcqrd4v0	383	21	by	by	IN
cord-017161-lcqrd4v0	383	22	perivascular	perivascular	NNP
cord-017161-lcqrd4v0	383	23	cuf	cuf	NNP
cord-017161-lcqrd4v0	383	24	fi	fi	NNP
cord-017161-lcqrd4v0	383	25	ng	ng	NNP
cord-017161-lcqrd4v0	383	26	mainly	mainly	RB
cord-017161-lcqrd4v0	383	27	composed	compose	VBN
cord-017161-lcqrd4v0	383	28	of	of	IN
cord-017161-lcqrd4v0	383	29	g	g	NN
cord-017161-lcqrd4v0	383	30	d	d	NN
cord-017161-lcqrd4v0	383	31	T	t	NN
cord-017161-lcqrd4v0	383	32	lymphocytes	lymphocyte	NNS
cord-017161-lcqrd4v0	383	33	,	,	,
cord-017161-lcqrd4v0	383	34	cytotoxic	cytotoxic	JJ
cord-017161-lcqrd4v0	383	35	lymphocytes	lymphocyte	NNS
cord-017161-lcqrd4v0	383	36	and	and	CC
cord-017161-lcqrd4v0	383	37	T	T	NNP
cord-017161-lcqrd4v0	383	38	helper	helper	NN
cord-017161-lcqrd4v0	383	39	cells	cell	NNS
cord-017161-lcqrd4v0	383	40	[	[	-LRB-
cord-017161-lcqrd4v0	383	41	217	217	CD
cord-017161-lcqrd4v0	383	42	]	]	-RRB-
cord-017161-lcqrd4v0	383	43	.	.	.
cord-017161-lcqrd4v0	384	1	Luminal	Luminal	NNP
cord-017161-lcqrd4v0	384	2	stenosis	stenosis	NN
cord-017161-lcqrd4v0	384	3	of	of	IN
cord-017161-lcqrd4v0	384	4	advential	advential	JJ
cord-017161-lcqrd4v0	384	5	small	small	JJ
cord-017161-lcqrd4v0	384	6	arteries	artery	NNS
cord-017161-lcqrd4v0	384	7	due	due	JJ
cord-017161-lcqrd4v0	384	8	to	to	IN
cord-017161-lcqrd4v0	384	9	intimal	intimal	JJ
cord-017161-lcqrd4v0	384	10	thickening	thickening	NN
cord-017161-lcqrd4v0	384	11	is	be	VBZ
cord-017161-lcqrd4v0	384	12	relatively	relatively	RB
cord-017161-lcqrd4v0	384	13	common	common	JJ
cord-017161-lcqrd4v0	384	14	[	[	-LRB-
cord-017161-lcqrd4v0	384	15	217	217	CD
cord-017161-lcqrd4v0	384	16	]	]	-RRB-
cord-017161-lcqrd4v0	384	17	.	.	.
cord-017161-lcqrd4v0	385	1	In	in	IN
cord-017161-lcqrd4v0	385	2	the	the	DT
cord-017161-lcqrd4v0	385	3	chronic	chronic	JJ
cord-017161-lcqrd4v0	385	4	stage	stage	NN
cord-017161-lcqrd4v0	385	5	of	of	IN
cord-017161-lcqrd4v0	385	6	TA	TA	NNP
cord-017161-lcqrd4v0	385	7	,	,	,
cord-017161-lcqrd4v0	385	8	intimal	intimal	JJ
cord-017161-lcqrd4v0	385	9	fi	fi	NN
cord-017161-lcqrd4v0	385	10	brosis	brosis	NN
cord-017161-lcqrd4v0	385	11	is	be	VBZ
cord-017161-lcqrd4v0	385	12	often	often	RB
cord-017161-lcqrd4v0	385	13	accompanied	accompany	VBN
cord-017161-lcqrd4v0	385	14	by	by	IN
cord-017161-lcqrd4v0	385	15	well	well	RB
cord-017161-lcqrd4v0	385	16	-	-	HYPH
cord-017161-lcqrd4v0	385	17	formed	form	VBN
cord-017161-lcqrd4v0	385	18	fi	fi	NN
cord-017161-lcqrd4v0	385	19	brous	brous	JJ
cord-017161-lcqrd4v0	385	20	atherosclerotic	atherosclerotic	JJ
cord-017161-lcqrd4v0	385	21	plaques	plaque	NNS
cord-017161-lcqrd4v0	385	22	and	and	CC
cord-017161-lcqrd4v0	385	23	calci	calci	NNP
cord-017161-lcqrd4v0	385	24	fi	fi	NNP
cord-017161-lcqrd4v0	385	25	cation	cation	NNP
cord-017161-lcqrd4v0	385	26	[	[	-LRB-
cord-017161-lcqrd4v0	385	27	217	217	CD
cord-017161-lcqrd4v0	385	28	]	]	-RRB-
cord-017161-lcqrd4v0	385	29	.	.	.
cord-017161-lcqrd4v0	386	1	Furthermore	furthermore	RB
cord-017161-lcqrd4v0	386	2	,	,	,
cord-017161-lcqrd4v0	386	3	autoantibodies	autoantibody	NNS
cord-017161-lcqrd4v0	386	4	against	against	IN
cord-017161-lcqrd4v0	386	5	aortic	aortic	JJ
cord-017161-lcqrd4v0	386	6	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	386	7	cells	cell	NNS
cord-017161-lcqrd4v0	386	8	have	have	VBP
cord-017161-lcqrd4v0	386	9	been	be	VBN
cord-017161-lcqrd4v0	386	10	proposed	propose	VBN
cord-017161-lcqrd4v0	386	11	as	as	IN
cord-017161-lcqrd4v0	386	12	a	a	DT
cord-017161-lcqrd4v0	386	13	key	key	JJ
cord-017161-lcqrd4v0	386	14	factor	factor	NN
cord-017161-lcqrd4v0	386	15	in	in	IN
cord-017161-lcqrd4v0	386	16	the	the	DT
cord-017161-lcqrd4v0	386	17	pathogenesis	pathogenesis	NN
cord-017161-lcqrd4v0	386	18	of	of	IN
cord-017161-lcqrd4v0	386	19	TA	TA	NNP
cord-017161-lcqrd4v0	386	20	[	[	-LRB-
cord-017161-lcqrd4v0	386	21	218	218	CD
cord-017161-lcqrd4v0	386	22	,	,	,
cord-017161-lcqrd4v0	386	23	219	219	CD
cord-017161-lcqrd4v0	386	24	]	]	-RRB-
cord-017161-lcqrd4v0	386	25	.	.	.
cord-017161-lcqrd4v0	387	1	Chauhan	Chauhan	NNP
cord-017161-lcqrd4v0	387	2	et	et	NNP
cord-017161-lcqrd4v0	387	3	al	al	NNP
cord-017161-lcqrd4v0	387	4	.	.	NNP
cord-017161-lcqrd4v0	387	5	reported	report	VBD
cord-017161-lcqrd4v0	387	6	that	that	IN
cord-017161-lcqrd4v0	387	7	patients	patient	NNS
cord-017161-lcqrd4v0	387	8	with	with	IN
cord-017161-lcqrd4v0	387	9	TA	TA	NNP
cord-017161-lcqrd4v0	387	10	show	show	NN
cord-017161-lcqrd4v0	387	11	circulating	circulate	VBG
cord-017161-lcqrd4v0	387	12	anti	anti	JJ
cord-017161-lcqrd4v0	387	13	-	-	JJ
cord-017161-lcqrd4v0	387	14	aortic	aortic	JJ
cord-017161-lcqrd4v0	387	15	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	387	16	cell	cell	NN
cord-017161-lcqrd4v0	387	17	antibodies	antibody	NNS
cord-017161-lcqrd4v0	387	18	(	(	-LRB-
cord-017161-lcqrd4v0	387	19	AAECAs	aaeca	NNS
cord-017161-lcqrd4v0	387	20	)	)	-RRB-
cord-017161-lcqrd4v0	387	21	directed	direct	VBN
cord-017161-lcqrd4v0	387	22	against	against	IN
cord-017161-lcqrd4v0	387	23	60	60	CD
cord-017161-lcqrd4v0	387	24	-	-	SYM
cord-017161-lcqrd4v0	387	25	65	65	CD
cord-017161-lcqrd4v0	387	26	kDa	kDa	NNP
cord-017161-lcqrd4v0	387	27	heat	heat	NN
cord-017161-lcqrd4v0	387	28	-	-	HYPH
cord-017161-lcqrd4v0	387	29	shock	shock	NN
cord-017161-lcqrd4v0	387	30	proteins	protein	NNS
cord-017161-lcqrd4v0	387	31	(	(	-LRB-
cord-017161-lcqrd4v0	387	32	HSPs	hsp	NNS
cord-017161-lcqrd4v0	387	33	60/65	60/65	CD
cord-017161-lcqrd4v0	387	34	)	)	-RRB-
cord-017161-lcqrd4v0	387	35	[	[	-LRB-
cord-017161-lcqrd4v0	387	36	218	218	CD
cord-017161-lcqrd4v0	387	37	,	,	,
cord-017161-lcqrd4v0	387	38	219	219	CD
cord-017161-lcqrd4v0	387	39	]	]	-RRB-
cord-017161-lcqrd4v0	387	40	.	.	.
cord-017161-lcqrd4v0	388	1	Sera	Sera	NNP
cord-017161-lcqrd4v0	388	2	from	from	IN
cord-017161-lcqrd4v0	388	3	AAECA	AAECA	NNP
cord-017161-lcqrd4v0	388	4	-	-	HYPH
cord-017161-lcqrd4v0	388	5	positive	positive	JJ
cord-017161-lcqrd4v0	388	6	patients	patient	NNS
cord-017161-lcqrd4v0	388	7	with	with	IN
cord-017161-lcqrd4v0	388	8	TA	TA	NNP
cord-017161-lcqrd4v0	388	9	were	be	VBD
cord-017161-lcqrd4v0	388	10	found	find	VBN
cord-017161-lcqrd4v0	388	11	to	to	TO
cord-017161-lcqrd4v0	388	12	induce	induce	VB
cord-017161-lcqrd4v0	388	13	apoptosis	apoptosis	NN
cord-017161-lcqrd4v0	388	14	of	of	IN
cord-017161-lcqrd4v0	388	15	aortic	aortic	JJ
cord-017161-lcqrd4v0	388	16	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	388	17	cells	cell	NNS
cord-017161-lcqrd4v0	388	18	,	,	,
cord-017161-lcqrd4v0	388	19	suggesting	suggest	VBG
cord-017161-lcqrd4v0	388	20	that	that	IN
cord-017161-lcqrd4v0	388	21	these	these	DT
cord-017161-lcqrd4v0	388	22	antibodies	antibody	NNS
cord-017161-lcqrd4v0	388	23	may	may	MD
cord-017161-lcqrd4v0	388	24	have	have	VB
cord-017161-lcqrd4v0	388	25	a	a	DT
cord-017161-lcqrd4v0	388	26	role	role	NN
cord-017161-lcqrd4v0	388	27	in	in	IN
cord-017161-lcqrd4v0	388	28	the	the	DT
cord-017161-lcqrd4v0	388	29	disease	disease	NN
cord-017161-lcqrd4v0	388	30	pathogenesis	pathogenesis	NN
cord-017161-lcqrd4v0	388	31	[	[	-LRB-
cord-017161-lcqrd4v0	388	32	218	218	CD
cord-017161-lcqrd4v0	388	33	]	]	-RRB-
cord-017161-lcqrd4v0	388	34	.	.	.
cord-017161-lcqrd4v0	389	1	Lastly	lastly	RB
cord-017161-lcqrd4v0	389	2	,	,	,
cord-017161-lcqrd4v0	389	3	while	while	IN
cord-017161-lcqrd4v0	389	4	previous	previous	JJ
cord-017161-lcqrd4v0	389	5	reports	report	NNS
cord-017161-lcqrd4v0	389	6	have	have	VBP
cord-017161-lcqrd4v0	389	7	suggested	suggest	VBN
cord-017161-lcqrd4v0	389	8	a	a	DT
cord-017161-lcqrd4v0	389	9	link	link	NN
cord-017161-lcqrd4v0	389	10	between	between	IN
cord-017161-lcqrd4v0	389	11	TA	TA	NNP
cord-017161-lcqrd4v0	389	12	and	and	CC
cord-017161-lcqrd4v0	389	13	tuberculosis	tuberculosis	NN
cord-017161-lcqrd4v0	389	14	,	,	,
cord-017161-lcqrd4v0	389	15	additional	additional	JJ
cord-017161-lcqrd4v0	389	16	studies	study	NNS
cord-017161-lcqrd4v0	389	17	have	have	VBP
cord-017161-lcqrd4v0	389	18	not	not	RB
cord-017161-lcqrd4v0	389	19	supported	support	VBN
cord-017161-lcqrd4v0	389	20	this	this	DT
cord-017161-lcqrd4v0	389	21	association	association	NN
cord-017161-lcqrd4v0	389	22	[	[	-LRB-
cord-017161-lcqrd4v0	389	23	220	220	CD
cord-017161-lcqrd4v0	389	24	]	]	-RRB-
cord-017161-lcqrd4v0	389	25	.	.	.
cord-017161-lcqrd4v0	390	1	Familial	familial	JJ
cord-017161-lcqrd4v0	390	2	occurrence	occurrence	NN
cord-017161-lcqrd4v0	390	3	of	of	IN
cord-017161-lcqrd4v0	390	4	the	the	DT
cord-017161-lcqrd4v0	390	5	disease	disease	NN
cord-017161-lcqrd4v0	390	6	has	have	VBZ
cord-017161-lcqrd4v0	390	7	been	be	VBN
cord-017161-lcqrd4v0	390	8	extensively	extensively	RB
cord-017161-lcqrd4v0	390	9	reported	report	VBN
cord-017161-lcqrd4v0	390	10	,	,	,
cord-017161-lcqrd4v0	390	11	leading	lead	VBG
cord-017161-lcqrd4v0	390	12	to	to	IN
cord-017161-lcqrd4v0	390	13	a	a	DT
cord-017161-lcqrd4v0	390	14	hypothesis	hypothesis	NN
cord-017161-lcqrd4v0	390	15	for	for	IN
cord-017161-lcqrd4v0	390	16	a	a	DT
cord-017161-lcqrd4v0	390	17	hereditary	hereditary	JJ
cord-017161-lcqrd4v0	390	18	basis	basis	NN
cord-017161-lcqrd4v0	390	19	[	[	-LRB-
cord-017161-lcqrd4v0	390	20	221	221	CD
cord-017161-lcqrd4v0	390	21	]	]	-RRB-
cord-017161-lcqrd4v0	390	22	.	.	.
cord-017161-lcqrd4v0	391	1	The	the	DT
cord-017161-lcqrd4v0	391	2	genetic	genetic	JJ
cord-017161-lcqrd4v0	391	3	association	association	NN
cord-017161-lcqrd4v0	391	4	of	of	IN
cord-017161-lcqrd4v0	391	5	TA	TA	NNP
cord-017161-lcqrd4v0	391	6	with	with	IN
cord-017161-lcqrd4v0	391	7	HLAB52	HLAB52	NNP
cord-017161-lcqrd4v0	391	8	,	,	,
cord-017161-lcqrd4v0	391	9	and	and	CC
cord-017161-lcqrd4v0	391	10	particularly	particularly	RB
cord-017161-lcqrd4v0	391	11	B*5201	B*5201	NNP
cord-017161-lcqrd4v0	391	12	that	that	DT
cord-017161-lcqrd4v0	391	13	has	have	VBZ
cord-017161-lcqrd4v0	391	14	been	be	VBN
cord-017161-lcqrd4v0	391	15	observed	observe	VBN
cord-017161-lcqrd4v0	391	16	,	,	,
cord-017161-lcqrd4v0	391	17	with	with	IN
cord-017161-lcqrd4v0	391	18	high	high	JJ
cord-017161-lcqrd4v0	391	19	estimated	estimate	VBN
cord-017161-lcqrd4v0	391	20	OR	or	CC
cord-017161-lcqrd4v0	391	21	(	(	-LRB-
cord-017161-lcqrd4v0	391	22	4.7	4.7	CD
cord-017161-lcqrd4v0	391	23	-	-	SYM
cord-017161-lcqrd4v0	391	24	10.2	10.2	CD
cord-017161-lcqrd4v0	391	25	)	)	-RRB-
cord-017161-lcqrd4v0	391	26	,	,	,
cord-017161-lcqrd4v0	391	27	in	in	IN
cord-017161-lcqrd4v0	391	28	multiple	multiple	JJ
cord-017161-lcqrd4v0	391	29	cohorts	cohort	NNS
cord-017161-lcqrd4v0	391	30	of	of	IN
cord-017161-lcqrd4v0	391	31	diverse	diverse	JJ
cord-017161-lcqrd4v0	391	32	ethnicity	ethnicity	NN
cord-017161-lcqrd4v0	391	33	(	(	-LRB-
cord-017161-lcqrd4v0	391	34	East	East	NNP
cord-017161-lcqrd4v0	391	35	Asia	Asia	NNP
cord-017161-lcqrd4v0	391	36	,	,	,
cord-017161-lcqrd4v0	391	37	South	South	NNP
cord-017161-lcqrd4v0	391	38	Asia	Asia	NNP
cord-017161-lcqrd4v0	391	39	and	and	CC
cord-017161-lcqrd4v0	391	40	Mexico	Mexico	NNP
cord-017161-lcqrd4v0	391	41	)	)	-RRB-
cord-017161-lcqrd4v0	391	42	[	[	-LRB-
cord-017161-lcqrd4v0	391	43	222	222	CD
cord-017161-lcqrd4v0	391	44	]	]	-RRB-
cord-017161-lcqrd4v0	391	45	.	.	.
cord-017161-lcqrd4v0	392	1	In	in	IN
cord-017161-lcqrd4v0	392	2	addition	addition	NN
cord-017161-lcqrd4v0	392	3	,	,	,
cord-017161-lcqrd4v0	392	4	a	a	DT
cord-017161-lcqrd4v0	392	5	hypothesis	hypothesis	NN
cord-017161-lcqrd4v0	392	6	was	be	VBD
cord-017161-lcqrd4v0	392	7	made	make	VBN
cord-017161-lcqrd4v0	392	8	,	,	,
cord-017161-lcqrd4v0	392	9	based	base	VBN
cord-017161-lcqrd4v0	392	10	on	on	IN
cord-017161-lcqrd4v0	392	11	a	a	DT
cord-017161-lcqrd4v0	392	12	Japanese	japanese	JJ
cord-017161-lcqrd4v0	392	13	cohort	cohort	NN
cord-017161-lcqrd4v0	392	14	,	,	,
cord-017161-lcqrd4v0	392	15	that	that	IN
cord-017161-lcqrd4v0	392	16	an	an	DT
cord-017161-lcqrd4v0	392	17	even	even	RB
cord-017161-lcqrd4v0	392	18	stronger	strong	JJR
cord-017161-lcqrd4v0	392	19	association	association	NN
cord-017161-lcqrd4v0	392	20	can	can	MD
cord-017161-lcqrd4v0	392	21	be	be	VB
cord-017161-lcqrd4v0	392	22	identi	identi	NNP
cord-017161-lcqrd4v0	392	23	fi	fi	NNP
cord-017161-lcqrd4v0	392	24	ed	ed	NN
cord-017161-lcqrd4v0	392	25	,	,	,
cord-017161-lcqrd4v0	392	26	considering	consider	VBG
cord-017161-lcqrd4v0	392	27	HLA	HLA	NNP
cord-017161-lcqrd4v0	392	28	alleles	allele	NNS
cord-017161-lcqrd4v0	392	29	that	that	WDT
cord-017161-lcqrd4v0	392	30	share	share	VBP
cord-017161-lcqrd4v0	392	31	the	the	DT
cord-017161-lcqrd4v0	392	32	motif	motif	NN
cord-017161-lcqrd4v0	392	33	of	of	IN
cord-017161-lcqrd4v0	392	34	glutamate	glutamate	NN
cord-017161-lcqrd4v0	392	35	at	at	IN
cord-017161-lcqrd4v0	392	36	position	position	NN
cord-017161-lcqrd4v0	392	37	63	63	CD
cord-017161-lcqrd4v0	392	38	and	and	CC
cord-017161-lcqrd4v0	392	39	serine	serine	NN
cord-017161-lcqrd4v0	392	40	at	at	IN
cord-017161-lcqrd4v0	392	41	position	position	NN
cord-017161-lcqrd4v0	392	42	67	67	CD
cord-017161-lcqrd4v0	392	43	,	,	,
cord-017161-lcqrd4v0	392	44	which	which	WDT
cord-017161-lcqrd4v0	392	45	characterizes	characterize	VBZ
cord-017161-lcqrd4v0	392	46	B*3902	B*3902	NNP
cord-017161-lcqrd4v0	392	47	as	as	RB
cord-017161-lcqrd4v0	392	48	well	well	RB
cord-017161-lcqrd4v0	392	49	as	as	IN
cord-017161-lcqrd4v0	392	50	B*5201	B*5201	NNP
cord-017161-lcqrd4v0	392	51	[	[	-LRB-
cord-017161-lcqrd4v0	392	52	223	223	CD
cord-017161-lcqrd4v0	392	53	]	]	-RRB-
cord-017161-lcqrd4v0	392	54	.	.	.
cord-017161-lcqrd4v0	393	1	Data	datum	NNS
cord-017161-lcqrd4v0	393	2	supporting	support	VBG
cord-017161-lcqrd4v0	393	3	this	this	DT
cord-017161-lcqrd4v0	393	4	hypothesis	hypothesis	NN
cord-017161-lcqrd4v0	393	5	were	be	VBD
cord-017161-lcqrd4v0	393	6	recently	recently	RB
cord-017161-lcqrd4v0	393	7	reported	report	VBN
cord-017161-lcqrd4v0	393	8	using	use	VBG
cord-017161-lcqrd4v0	393	9	a	a	DT
cord-017161-lcqrd4v0	393	10	Mexican	mexican	JJ
cord-017161-lcqrd4v0	393	11	cohort	cohort	NN
cord-017161-lcqrd4v0	393	12	[	[	-LRB-
cord-017161-lcqrd4v0	393	13	222	222	CD
cord-017161-lcqrd4v0	393	14	]	]	-RRB-
cord-017161-lcqrd4v0	393	15	.	.	.
cord-017161-lcqrd4v0	394	1	Candidate	candidate	NN
cord-017161-lcqrd4v0	394	2	gene	gene	NN
cord-017161-lcqrd4v0	394	3	studies	study	NNS
cord-017161-lcqrd4v0	394	4	have	have	VBP
cord-017161-lcqrd4v0	394	5	also	also	RB
cord-017161-lcqrd4v0	394	6	reported	report	VBN
cord-017161-lcqrd4v0	394	7	associations	association	NNS
cord-017161-lcqrd4v0	394	8	with	with	IN
cord-017161-lcqrd4v0	394	9	interleukin	interleukin	NN
cord-017161-lcqrd4v0	394	10	(	(	-LRB-
cord-017161-lcqrd4v0	394	11	IL)-12	il)-12	NN
cord-017161-lcqrd4v0	394	12	,	,	,
cord-017161-lcqrd4v0	394	13	IL-2	IL-2	NNP
cord-017161-lcqrd4v0	394	14	and	and	CC
cord-017161-lcqrd4v0	394	15	IL-6	IL-6	NNP
cord-017161-lcqrd4v0	394	16	gene	gene	NN
cord-017161-lcqrd4v0	394	17	polymorphisms	polymorphism	NNS
cord-017161-lcqrd4v0	394	18	in	in	IN
cord-017161-lcqrd4v0	394	19	a	a	DT
cord-017161-lcqrd4v0	394	20	Turkish	turkish	JJ
cord-017161-lcqrd4v0	394	21	cohort	cohort	NN
cord-017161-lcqrd4v0	394	22	but	but	CC
cord-017161-lcqrd4v0	394	23	have	have	VBP
cord-017161-lcqrd4v0	394	24	not	not	RB
cord-017161-lcqrd4v0	394	25	been	be	VBN
cord-017161-lcqrd4v0	394	26	replicated	replicate	VBN
cord-017161-lcqrd4v0	394	27	[	[	-LRB-
cord-017161-lcqrd4v0	394	28	4	4	CD
cord-017161-lcqrd4v0	394	29	,	,	,
cord-017161-lcqrd4v0	394	30	32	32	CD
cord-017161-lcqrd4v0	394	31	]	]	-RRB-
cord-017161-lcqrd4v0	394	32	.	.	.
cord-017161-lcqrd4v0	395	1	Clinical	clinical	JJ
cord-017161-lcqrd4v0	395	2	diagnosis	diagnosis	NN
cord-017161-lcqrd4v0	395	3	of	of	IN
cord-017161-lcqrd4v0	395	4	TA	TA	NNP
cord-017161-lcqrd4v0	395	5	is	be	VBZ
cord-017161-lcqrd4v0	395	6	commonly	commonly	RB
cord-017161-lcqrd4v0	395	7	challenging	challenge	VBG
cord-017161-lcqrd4v0	395	8	for	for	IN
cord-017161-lcqrd4v0	395	9	the	the	DT
cord-017161-lcqrd4v0	395	10	clinician	clinician	NN
cord-017161-lcqrd4v0	395	11	.	.	.
cord-017161-lcqrd4v0	396	1	It	-PRON-	PRP
cord-017161-lcqrd4v0	396	2	is	be	VBZ
cord-017161-lcqrd4v0	396	3	estimated	estimate	VBN
cord-017161-lcqrd4v0	396	4	that	that	IN
cord-017161-lcqrd4v0	396	5	one	one	CD
cord-017161-lcqrd4v0	396	6	-	-	HYPH
cord-017161-lcqrd4v0	396	7	third	third	NN
cord-017161-lcqrd4v0	396	8	of	of	IN
cord-017161-lcqrd4v0	396	9	children	child	NNS
cord-017161-lcqrd4v0	396	10	present	present	JJ
cord-017161-lcqrd4v0	396	11	with	with	IN
cord-017161-lcqrd4v0	396	12	inactive	inactive	JJ
cord-017161-lcqrd4v0	396	13	,	,	,
cord-017161-lcqrd4v0	396	14	so	so	RB
cord-017161-lcqrd4v0	396	15	-	-	HYPH
cord-017161-lcqrd4v0	396	16	called	call	VBN
cord-017161-lcqrd4v0	396	17	burnt	burn	VBN
cord-017161-lcqrd4v0	396	18	-	-	HYPH
cord-017161-lcqrd4v0	396	19	out	out	RP
cord-017161-lcqrd4v0	396	20	stage	stage	NN
cord-017161-lcqrd4v0	396	21	of	of	IN
cord-017161-lcqrd4v0	396	22	disease	disease	NN
cord-017161-lcqrd4v0	396	23	,	,	,
cord-017161-lcqrd4v0	396	24	in	in	IN
cord-017161-lcqrd4v0	396	25	which	which	WDT
cord-017161-lcqrd4v0	396	26	clinical	clinical	JJ
cord-017161-lcqrd4v0	396	27	features	feature	NNS
cord-017161-lcqrd4v0	396	28	represent	represent	VBP
cord-017161-lcqrd4v0	396	29	vascular	vascular	JJ
cord-017161-lcqrd4v0	396	30	sequelae	sequela	NNS
cord-017161-lcqrd4v0	396	31	rather	rather	RB
cord-017161-lcqrd4v0	396	32	than	than	IN
cord-017161-lcqrd4v0	396	33	active	active	JJ
cord-017161-lcqrd4v0	396	34	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	396	35	[	[	-LRB-
cord-017161-lcqrd4v0	396	36	216	216	CD
cord-017161-lcqrd4v0	396	37	]	]	-RRB-
cord-017161-lcqrd4v0	396	38	.	.	.
cord-017161-lcqrd4v0	397	1	The	the	DT
cord-017161-lcqrd4v0	397	2	natural	natural	JJ
cord-017161-lcqrd4v0	397	3	history	history	NN
cord-017161-lcqrd4v0	397	4	and	and	CC
cord-017161-lcqrd4v0	397	5	the	the	DT
cord-017161-lcqrd4v0	397	6	time	time	NN
cord-017161-lcqrd4v0	397	7	from	from	IN
cord-017161-lcqrd4v0	397	8	onset	onset	NN
cord-017161-lcqrd4v0	397	9	of	of	IN
cord-017161-lcqrd4v0	397	10	symptoms	symptom	NNS
cord-017161-lcqrd4v0	397	11	to	to	IN
cord-017161-lcqrd4v0	397	12	diagnosis	diagnosis	NN
cord-017161-lcqrd4v0	397	13	are	be	VBP
cord-017161-lcqrd4v0	397	14	variable	variable	JJ
cord-017161-lcqrd4v0	397	15	.	.	.
cord-017161-lcqrd4v0	398	1	The	the	DT
cord-017161-lcqrd4v0	398	2	clinical	clinical	JJ
cord-017161-lcqrd4v0	398	3	spectrum	spectrum	NN
cord-017161-lcqrd4v0	398	4	at	at	IN
cord-017161-lcqrd4v0	398	5	presentation	presentation	NN
cord-017161-lcqrd4v0	398	6	of	of	IN
cord-017161-lcqrd4v0	398	7	children	child	NNS
cord-017161-lcqrd4v0	398	8	with	with	IN
cord-017161-lcqrd4v0	398	9	TA	TA	NNP
cord-017161-lcqrd4v0	398	10	differs	differ	VBZ
cord-017161-lcqrd4v0	398	11	from	from	IN
cord-017161-lcqrd4v0	398	12	that	that	DT
cord-017161-lcqrd4v0	398	13	of	of	IN
cord-017161-lcqrd4v0	398	14	adults	adult	NNS
cord-017161-lcqrd4v0	398	15	;	;	:
cord-017161-lcqrd4v0	398	16	however	however	RB
cord-017161-lcqrd4v0	398	17	,	,	,
cord-017161-lcqrd4v0	398	18	hypertension	hypertension	NN
cord-017161-lcqrd4v0	398	19	is	be	VBZ
cord-017161-lcqrd4v0	398	20	the	the	DT
cord-017161-lcqrd4v0	398	21	most	most	RBS
cord-017161-lcqrd4v0	398	22	common	common	JJ
cord-017161-lcqrd4v0	398	23	symptom	symptom	NN
cord-017161-lcqrd4v0	398	24	in	in	IN
cord-017161-lcqrd4v0	398	25	both	both	DT
cord-017161-lcqrd4v0	398	26	groups	group	NNS
cord-017161-lcqrd4v0	398	27	[	[	-LRB-
cord-017161-lcqrd4v0	398	28	216	216	CD
cord-017161-lcqrd4v0	398	29	]	]	-RRB-
cord-017161-lcqrd4v0	398	30	.	.	.
cord-017161-lcqrd4v0	399	1	Cakar	Cakar	NNP
cord-017161-lcqrd4v0	399	2	et	et	FW
cord-017161-lcqrd4v0	399	3	al	al	NNP
cord-017161-lcqrd4v0	399	4	.	.	.
cord-017161-lcqrd4v0	400	1	recently	recently	RB
cord-017161-lcqrd4v0	400	2	reported	report	VBN
cord-017161-lcqrd4v0	400	3	in	in	IN
cord-017161-lcqrd4v0	400	4	a	a	DT
cord-017161-lcqrd4v0	400	5	series	series	NN
cord-017161-lcqrd4v0	400	6	of	of	IN
cord-017161-lcqrd4v0	400	7	19	19	CD
cord-017161-lcqrd4v0	400	8	children	child	NNS
cord-017161-lcqrd4v0	400	9	with	with	IN
cord-017161-lcqrd4v0	400	10	TA	TA	NNP
cord-017161-lcqrd4v0	400	11	that	that	IN
cord-017161-lcqrd4v0	400	12	the	the	DT
cord-017161-lcqrd4v0	400	13	most	most	RBS
cord-017161-lcqrd4v0	400	14	common	common	JJ
cord-017161-lcqrd4v0	400	15	complaints	complaint	NNS
cord-017161-lcqrd4v0	400	16	at	at	IN
cord-017161-lcqrd4v0	400	17	presentation	presentation	NN
cord-017161-lcqrd4v0	400	18	were	be	VBD
cord-017161-lcqrd4v0	400	19	headache	headache	NN
cord-017161-lcqrd4v0	400	20	(	(	-LRB-
cord-017161-lcqrd4v0	400	21	84	84	CD
cord-017161-lcqrd4v0	400	22	%	%	NN
cord-017161-lcqrd4v0	400	23	)	)	-RRB-
cord-017161-lcqrd4v0	400	24	,	,	,
cord-017161-lcqrd4v0	400	25	abdominal	abdominal	JJ
cord-017161-lcqrd4v0	400	26	pain	pain	NN
cord-017161-lcqrd4v0	400	27	(	(	-LRB-
cord-017161-lcqrd4v0	400	28	37	37	CD
cord-017161-lcqrd4v0	400	29	%	%	NN
cord-017161-lcqrd4v0	400	30	)	)	-RRB-
cord-017161-lcqrd4v0	400	31	,	,	,
cord-017161-lcqrd4v0	400	32	claudication	claudication	NN
cord-017161-lcqrd4v0	400	33	of	of	IN
cord-017161-lcqrd4v0	400	34	extremities	extremity	NNS
cord-017161-lcqrd4v0	400	35	(	(	-LRB-
cord-017161-lcqrd4v0	400	36	32	32	CD
cord-017161-lcqrd4v0	400	37	%	%	NN
cord-017161-lcqrd4v0	400	38	)	)	-RRB-
cord-017161-lcqrd4v0	400	39	,	,	,
cord-017161-lcqrd4v0	400	40	fever	fever	NN
cord-017161-lcqrd4v0	400	41	(	(	-LRB-
cord-017161-lcqrd4v0	400	42	26	26	CD
cord-017161-lcqrd4v0	400	43	%	%	NN
cord-017161-lcqrd4v0	400	44	)	)	-RRB-
cord-017161-lcqrd4v0	400	45	and	and	CC
cord-017161-lcqrd4v0	400	46	weight	weight	NN
cord-017161-lcqrd4v0	400	47	loss	loss	NN
cord-017161-lcqrd4v0	400	48	(	(	-LRB-
cord-017161-lcqrd4v0	400	49	10	10	CD
cord-017161-lcqrd4v0	400	50	%	%	NN
cord-017161-lcqrd4v0	400	51	)	)	-RRB-
cord-017161-lcqrd4v0	400	52	[	[	-LRB-
cord-017161-lcqrd4v0	400	53	224	224	CD
cord-017161-lcqrd4v0	400	54	]	]	-RRB-
cord-017161-lcqrd4v0	400	55	.	.	.
cord-017161-lcqrd4v0	401	1	One	one	CD
cord-017161-lcqrd4v0	401	2	child	child	NN
cord-017161-lcqrd4v0	401	3	presented	present	VBN
cord-017161-lcqrd4v0	401	4	with	with	IN
cord-017161-lcqrd4v0	401	5	visual	visual	JJ
cord-017161-lcqrd4v0	401	6	loss	loss	NN
cord-017161-lcqrd4v0	401	7	.	.	.
cord-017161-lcqrd4v0	402	1	Examination	examination	NN
cord-017161-lcqrd4v0	402	2	on	on	IN
cord-017161-lcqrd4v0	402	3	admission	admission	NN
cord-017161-lcqrd4v0	402	4	revealed	reveal	VBD
cord-017161-lcqrd4v0	402	5	hypertension	hypertension	NN
cord-017161-lcqrd4v0	402	6	(	(	-LRB-
cord-017161-lcqrd4v0	402	7	89	89	CD
cord-017161-lcqrd4v0	402	8	%	%	NN
cord-017161-lcqrd4v0	402	9	)	)	-RRB-
cord-017161-lcqrd4v0	402	10	,	,	,
cord-017161-lcqrd4v0	402	11	absent	absent	JJ
cord-017161-lcqrd4v0	402	12	pulses	pulse	NNS
cord-017161-lcqrd4v0	402	13	(	(	-LRB-
cord-017161-lcqrd4v0	402	14	58	58	CD
cord-017161-lcqrd4v0	402	15	%	%	NN
cord-017161-lcqrd4v0	402	16	)	)	-RRB-
cord-017161-lcqrd4v0	402	17	and	and	CC
cord-017161-lcqrd4v0	402	18	arterial	arterial	JJ
cord-017161-lcqrd4v0	402	19	bruits	bruit	NNS
cord-017161-lcqrd4v0	402	20	(	(	-LRB-
cord-017161-lcqrd4v0	402	21	42	42	CD
cord-017161-lcqrd4v0	402	22	%	%	NN
cord-017161-lcqrd4v0	402	23	)	)	-RRB-
cord-017161-lcqrd4v0	402	24	in	in	IN
cord-017161-lcqrd4v0	402	25	the	the	DT
cord-017161-lcqrd4v0	402	26	same	same	JJ
cord-017161-lcqrd4v0	402	27	cohort	cohort	NN
cord-017161-lcqrd4v0	402	28	[	[	-LRB-
cord-017161-lcqrd4v0	402	29	224	224	CD
cord-017161-lcqrd4v0	402	30	]	]	-RRB-
cord-017161-lcqrd4v0	402	31	.	.	.
cord-017161-lcqrd4v0	403	1	Corticosteroids	corticosteroid	NNS
cord-017161-lcqrd4v0	403	2	are	be	VBP
cord-017161-lcqrd4v0	403	3	still	still	RB
cord-017161-lcqrd4v0	403	4	the	the	DT
cord-017161-lcqrd4v0	403	5	mainstay	mainstay	NN
cord-017161-lcqrd4v0	403	6	of	of	IN
cord-017161-lcqrd4v0	403	7	treatment	treatment	NN
cord-017161-lcqrd4v0	403	8	for	for	IN
cord-017161-lcqrd4v0	403	9	TA	TA	NNP
cord-017161-lcqrd4v0	403	10	[	[	-LRB-
cord-017161-lcqrd4v0	403	11	4	4	CD
cord-017161-lcqrd4v0	403	12	,	,	,
cord-017161-lcqrd4v0	403	13	216	216	CD
cord-017161-lcqrd4v0	403	14	]	]	-RRB-
cord-017161-lcqrd4v0	403	15	.	.	.
cord-017161-lcqrd4v0	404	1	In	in	IN
cord-017161-lcqrd4v0	404	2	addition	addition	NN
cord-017161-lcqrd4v0	404	3	,	,	,
cord-017161-lcqrd4v0	404	4	MTX	MTX	NNP
cord-017161-lcqrd4v0	404	5	,	,	,
cord-017161-lcqrd4v0	404	6	azathioprine	azathioprine	NN
cord-017161-lcqrd4v0	404	7	,	,	,
cord-017161-lcqrd4v0	404	8	MMF	mmf	NN
cord-017161-lcqrd4v0	404	9	and	and	CC
cord-017161-lcqrd4v0	404	10	cyclophosphamide	cyclophosphamide	RB
cord-017161-lcqrd4v0	404	11	have	have	VBP
cord-017161-lcqrd4v0	404	12	been	be	VBN
cord-017161-lcqrd4v0	404	13	used	use	VBN
cord-017161-lcqrd4v0	404	14	in	in	IN
cord-017161-lcqrd4v0	404	15	children	child	NNS
cord-017161-lcqrd4v0	404	16	[	[	-LRB-
cord-017161-lcqrd4v0	404	17	4	4	CD
cord-017161-lcqrd4v0	404	18	,	,	,
cord-017161-lcqrd4v0	404	19	216	216	CD
cord-017161-lcqrd4v0	404	20	]	]	-RRB-
cord-017161-lcqrd4v0	404	21	.	.	.
cord-017161-lcqrd4v0	405	1	Ozen	Ozen	NNP
cord-017161-lcqrd4v0	405	2	et	et	FW
cord-017161-lcqrd4v0	405	3	al	al	NNP
cord-017161-lcqrd4v0	405	4	.	.	.
cord-017161-lcqrd4v0	406	1	described	describe	VBN
cord-017161-lcqrd4v0	406	2	six	six	CD
cord-017161-lcqrd4v0	406	3	children	child	NNS
cord-017161-lcqrd4v0	406	4	with	with	IN
cord-017161-lcqrd4v0	406	5	TA	TA	NNP
cord-017161-lcqrd4v0	406	6	,	,	,
cord-017161-lcqrd4v0	406	7	and	and	CC
cord-017161-lcqrd4v0	406	8	treatment	treatment	NN
cord-017161-lcqrd4v0	406	9	with	with	IN
cord-017161-lcqrd4v0	406	10	steroid	steroid	NN
cord-017161-lcqrd4v0	406	11	and	and	CC
cord-017161-lcqrd4v0	406	12	cyclophosphamide	cyclophosphamide	NN
cord-017161-lcqrd4v0	406	13	induction	induction	NN
cord-017161-lcqrd4v0	406	14	followed	follow	VBN
cord-017161-lcqrd4v0	406	15	by	by	IN
cord-017161-lcqrd4v0	406	16	MTX	MTX	NNP
cord-017161-lcqrd4v0	406	17	was	be	VBD
cord-017161-lcqrd4v0	406	18	suggested	suggest	VBN
cord-017161-lcqrd4v0	406	19	as	as	IN
cord-017161-lcqrd4v0	406	20	effective	effective	JJ
cord-017161-lcqrd4v0	406	21	and	and	CC
cord-017161-lcqrd4v0	406	22	safe	safe	JJ
cord-017161-lcqrd4v0	406	23	for	for	IN
cord-017161-lcqrd4v0	406	24	childhood	childhood	NN
cord-017161-lcqrd4v0	406	25	TA	TA	NNP
cord-017161-lcqrd4v0	406	26	with	with	IN
cord-017161-lcqrd4v0	406	27	widespread	widespread	JJ
cord-017161-lcqrd4v0	406	28	disease	disease	NN
cord-017161-lcqrd4v0	406	29	[	[	-LRB-
cord-017161-lcqrd4v0	406	30	225	225	CD
cord-017161-lcqrd4v0	406	31	]	]	-RRB-
cord-017161-lcqrd4v0	406	32	.	.	.
cord-017161-lcqrd4v0	407	1	Anti	Anti	NNP
cord-017161-lcqrd4v0	407	2	-	-	JJ
cord-017161-lcqrd4v0	407	3	TNF	TNF	NNP
cord-017161-lcqrd4v0	407	4	therapy	therapy	NN
cord-017161-lcqrd4v0	407	5	may	may	MD
cord-017161-lcqrd4v0	407	6	be	be	VB
cord-017161-lcqrd4v0	407	7	bene	bene	NNP
cord-017161-lcqrd4v0	407	8	fi	fi	NN
cord-017161-lcqrd4v0	407	9	cial	cial	NN
cord-017161-lcqrd4v0	407	10	[	[	-LRB-
cord-017161-lcqrd4v0	407	11	226	226	CD
cord-017161-lcqrd4v0	407	12	]	]	-RRB-
cord-017161-lcqrd4v0	407	13	.	.	.
cord-017161-lcqrd4v0	408	1	Surgical	surgical	JJ
cord-017161-lcqrd4v0	408	2	intervention	intervention	NN
cord-017161-lcqrd4v0	408	3	is	be	VBZ
cord-017161-lcqrd4v0	408	4	frequently	frequently	RB
cord-017161-lcqrd4v0	408	5	required	require	VBN
cord-017161-lcqrd4v0	408	6	to	to	TO
cord-017161-lcqrd4v0	408	7	alleviate	alleviate	VB
cord-017161-lcqrd4v0	408	8	end	end	NN
cord-017161-lcqrd4v0	408	9	-	-	HYPH
cord-017161-lcqrd4v0	408	10	organ	organ	NN
cord-017161-lcqrd4v0	408	11	ischemia	ischemia	NN
cord-017161-lcqrd4v0	408	12	and	and	CC
cord-017161-lcqrd4v0	408	13	hypertension	hypertension	NN
cord-017161-lcqrd4v0	408	14	resulting	result	VBG
cord-017161-lcqrd4v0	408	15	from	from	IN
cord-017161-lcqrd4v0	408	16	vascular	vascular	JJ
cord-017161-lcqrd4v0	408	17	stenoses	stenosis	NNS
cord-017161-lcqrd4v0	408	18	[	[	-LRB-
cord-017161-lcqrd4v0	408	19	216	216	CD
cord-017161-lcqrd4v0	408	20	]	]	-RRB-
cord-017161-lcqrd4v0	408	21	.	.	.
cord-017161-lcqrd4v0	409	1	The	the	DT
cord-017161-lcqrd4v0	409	2	mortality	mortality	NN
cord-017161-lcqrd4v0	409	3	rate	rate	NN
cord-017161-lcqrd4v0	409	4	in	in	IN
cord-017161-lcqrd4v0	409	5	children	child	NNS
cord-017161-lcqrd4v0	409	6	has	have	VBZ
cord-017161-lcqrd4v0	409	7	been	be	VBN
cord-017161-lcqrd4v0	409	8	reported	report	VBN
cord-017161-lcqrd4v0	409	9	as	as	RB
cord-017161-lcqrd4v0	409	10	high	high	JJ
cord-017161-lcqrd4v0	409	11	as	as	IN
cord-017161-lcqrd4v0	409	12	35	35	CD
cord-017161-lcqrd4v0	409	13	%	%	NN
cord-017161-lcqrd4v0	409	14	[	[	-LRB-
cord-017161-lcqrd4v0	409	15	216	216	CD
cord-017161-lcqrd4v0	409	16	]	]	-RRB-
cord-017161-lcqrd4v0	409	17	.	.	.
cord-017161-lcqrd4v0	410	1	The	the	DT
cord-017161-lcqrd4v0	410	2	outcome	outcome	NN
cord-017161-lcqrd4v0	410	3	depends	depend	VBZ
cord-017161-lcqrd4v0	410	4	on	on	IN
cord-017161-lcqrd4v0	410	5	the	the	DT
cord-017161-lcqrd4v0	410	6	vessel	vessel	NN
cord-017161-lcqrd4v0	410	7	involvement	involvement	NN
cord-017161-lcqrd4v0	410	8	and	and	CC
cord-017161-lcqrd4v0	410	9	on	on	IN
cord-017161-lcqrd4v0	410	10	the	the	DT
cord-017161-lcqrd4v0	410	11	severity	severity	NN
cord-017161-lcqrd4v0	410	12	of	of	IN
cord-017161-lcqrd4v0	410	13	hypertension	hypertension	NN
cord-017161-lcqrd4v0	410	14	[	[	-LRB-
cord-017161-lcqrd4v0	410	15	216	216	CD
cord-017161-lcqrd4v0	410	16	]	]	-RRB-
cord-017161-lcqrd4v0	410	17	.	.	.
cord-017161-lcqrd4v0	411	1	Initially	initially	RB
cord-017161-lcqrd4v0	411	2	considered	consider	VBN
cord-017161-lcqrd4v0	411	3	as	as	IN
cord-017161-lcqrd4v0	411	4	a	a	DT
cord-017161-lcqrd4v0	411	5	single	single	JJ
cord-017161-lcqrd4v0	411	6	cell	cell	NN
cord-017161-lcqrd4v0	411	7	lining	lining	NN
cord-017161-lcqrd4v0	411	8	of	of	IN
cord-017161-lcqrd4v0	411	9	the	the	DT
cord-017161-lcqrd4v0	411	10	vascular	vascular	JJ
cord-017161-lcqrd4v0	411	11	tree	tree	NN
cord-017161-lcqrd4v0	411	12	,	,	,
cord-017161-lcqrd4v0	411	13	the	the	DT
cord-017161-lcqrd4v0	411	14	endothelium	endothelium	NN
cord-017161-lcqrd4v0	411	15	has	have	VBZ
cord-017161-lcqrd4v0	411	16	recently	recently	RB
cord-017161-lcqrd4v0	411	17	emerged	emerge	VBN
cord-017161-lcqrd4v0	411	18	as	as	IN
cord-017161-lcqrd4v0	411	19	a	a	DT
cord-017161-lcqrd4v0	411	20	dynamic	dynamic	JJ
cord-017161-lcqrd4v0	411	21	interface	interface	NN
cord-017161-lcqrd4v0	411	22	responsive	responsive	JJ
cord-017161-lcqrd4v0	411	23	to	to	IN
cord-017161-lcqrd4v0	411	24	environmental	environmental	JJ
cord-017161-lcqrd4v0	411	25	stimuli	stimulus	NNS
cord-017161-lcqrd4v0	411	26	[	[	-LRB-
cord-017161-lcqrd4v0	411	27	227	227	CD
cord-017161-lcqrd4v0	411	28	]	]	-RRB-
cord-017161-lcqrd4v0	411	29	.	.	.
cord-017161-lcqrd4v0	412	1	As	as	IN
cord-017161-lcqrd4v0	412	2	a	a	DT
cord-017161-lcqrd4v0	412	3	result	result	NN
cord-017161-lcqrd4v0	412	4	,	,	,
cord-017161-lcqrd4v0	412	5	alteration	alteration	NN
cord-017161-lcqrd4v0	412	6	of	of	IN
cord-017161-lcqrd4v0	412	7	the	the	DT
cord-017161-lcqrd4v0	412	8	endothelium	endothelium	NN
cord-017161-lcqrd4v0	412	9	generates	generate	VBZ
cord-017161-lcqrd4v0	412	10	a	a	DT
cord-017161-lcqrd4v0	412	11	repertoire	repertoire	NN
cord-017161-lcqrd4v0	412	12	of	of	IN
cord-017161-lcqrd4v0	412	13	biological	biological	JJ
cord-017161-lcqrd4v0	412	14	responses	response	NNS
cord-017161-lcqrd4v0	412	15	playing	play	VBG
cord-017161-lcqrd4v0	412	16	a	a	DT
cord-017161-lcqrd4v0	412	17	key	key	JJ
cord-017161-lcqrd4v0	412	18	role	role	NN
cord-017161-lcqrd4v0	412	19	in	in	IN
cord-017161-lcqrd4v0	412	20	the	the	DT
cord-017161-lcqrd4v0	412	21	control	control	NN
cord-017161-lcqrd4v0	412	22	of	of	IN
cord-017161-lcqrd4v0	412	23	vascular	vascular	JJ
cord-017161-lcqrd4v0	412	24	homeostasis	homeostasis	NN
cord-017161-lcqrd4v0	412	25	such	such	JJ
cord-017161-lcqrd4v0	412	26	as	as	IN
cord-017161-lcqrd4v0	412	27	haemostasis	haemostasis	NN
cord-017161-lcqrd4v0	412	28	,	,	,
cord-017161-lcqrd4v0	412	29	in	in	IN
cord-017161-lcqrd4v0	412	30	fl	fl	NNP
cord-017161-lcqrd4v0	412	31	ammation	ammation	NN
cord-017161-lcqrd4v0	412	32	or	or	CC
cord-017161-lcqrd4v0	412	33	angiogenesis	angiogenesis	NN
cord-017161-lcqrd4v0	412	34	[	[	-LRB-
cord-017161-lcqrd4v0	412	35	228	228	CD
cord-017161-lcqrd4v0	412	36	]	]	-RRB-
cord-017161-lcqrd4v0	412	37	.	.	.
cord-017161-lcqrd4v0	413	1	As	as	IN
cord-017161-lcqrd4v0	413	2	a	a	DT
cord-017161-lcqrd4v0	413	3	consequence	consequence	NN
cord-017161-lcqrd4v0	413	4	,	,	,
cord-017161-lcqrd4v0	413	5	the	the	DT
cord-017161-lcqrd4v0	413	6	endothelium	endothelium	NN
cord-017161-lcqrd4v0	413	7	not	not	RB
cord-017161-lcqrd4v0	413	8	only	only	RB
cord-017161-lcqrd4v0	413	9	displays	display	NNS
cord-017161-lcqrd4v0	413	10	altered	alter	VBN
cord-017161-lcqrd4v0	413	11	functions	function	NNS
cord-017161-lcqrd4v0	413	12	but	but	CC
cord-017161-lcqrd4v0	413	13	also	also	RB
cord-017161-lcqrd4v0	413	14	loses	lose	VBZ
cord-017161-lcqrd4v0	413	15	its	-PRON-	PRP$
cord-017161-lcqrd4v0	413	16	integrity	integrity	NN
cord-017161-lcqrd4v0	413	17	.	.	.
cord-017161-lcqrd4v0	414	1	Endothelial	endothelial	JJ
cord-017161-lcqrd4v0	414	2	microparticles	microparticle	NNS
cord-017161-lcqrd4v0	414	3	(	(	-LRB-
cord-017161-lcqrd4v0	414	4	EMPs	emp	NNS
cord-017161-lcqrd4v0	414	5	)	)	-RRB-
cord-017161-lcqrd4v0	414	6	released	release	VBN
cord-017161-lcqrd4v0	414	7	from	from	IN
cord-017161-lcqrd4v0	414	8	activated	activate	VBN
cord-017161-lcqrd4v0	414	9	or	or	CC
cord-017161-lcqrd4v0	414	10	apoptotic	apoptotic	JJ
cord-017161-lcqrd4v0	414	11	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	414	12	cells	cell	NNS
cord-017161-lcqrd4v0	414	13	and	and	CC
cord-017161-lcqrd4v0	414	14	whole	whole	JJ
cord-017161-lcqrd4v0	414	15	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	414	16	cells	cell	NNS
cord-017161-lcqrd4v0	414	17	,	,	,
cord-017161-lcqrd4v0	414	18	circulating	circulate	VBG
cord-017161-lcqrd4v0	414	19	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	414	20	cells	cell	NNS
cord-017161-lcqrd4v0	414	21	(	(	-LRB-
cord-017161-lcqrd4v0	414	22	CECs	CECs	NNP
cord-017161-lcqrd4v0	414	23	)	)	-RRB-
cord-017161-lcqrd4v0	414	24	,	,	,
cord-017161-lcqrd4v0	414	25	detached	detach	VBN
cord-017161-lcqrd4v0	414	26	from	from	IN
cord-017161-lcqrd4v0	414	27	injured	injured	JJ
cord-017161-lcqrd4v0	414	28	vessels	vessel	NNS
cord-017161-lcqrd4v0	414	29	constitute	constitute	VBP
cord-017161-lcqrd4v0	414	30	a	a	DT
cord-017161-lcqrd4v0	414	31	fundamental	fundamental	JJ
cord-017161-lcqrd4v0	414	32	feature	feature	NN
cord-017161-lcqrd4v0	414	33	of	of	IN
cord-017161-lcqrd4v0	414	34	these	these	DT
cord-017161-lcqrd4v0	414	35	injurious	injurious	JJ
cord-017161-lcqrd4v0	414	36	responses	response	NNS
cord-017161-lcqrd4v0	414	37	affecting	affect	VBG
cord-017161-lcqrd4v0	414	38	the	the	DT
cord-017161-lcqrd4v0	414	39	vessel	vessel	NN
cord-017161-lcqrd4v0	414	40	wall	wall	NN
cord-017161-lcqrd4v0	414	41	[	[	-LRB-
cord-017161-lcqrd4v0	414	42	229	229	CD
cord-017161-lcqrd4v0	414	43	]	]	-RRB-
cord-017161-lcqrd4v0	414	44	[	[	-LRB-
cord-017161-lcqrd4v0	414	45	230	230	CD
cord-017161-lcqrd4v0	414	46	]	]	-RRB-
cord-017161-lcqrd4v0	414	47	[	[	-LRB-
cord-017161-lcqrd4v0	414	48	231	231	CD
cord-017161-lcqrd4v0	414	49	]	]	-RRB-
cord-017161-lcqrd4v0	414	50	.	.	.
cord-017161-lcqrd4v0	415	1	In	in	IN
cord-017161-lcqrd4v0	415	2	response	response	NN
cord-017161-lcqrd4v0	415	3	to	to	IN
cord-017161-lcqrd4v0	415	4	injury	injury	NN
cord-017161-lcqrd4v0	415	5	,	,	,
cord-017161-lcqrd4v0	415	6	regenerative	regenerative	JJ
cord-017161-lcqrd4v0	415	7	mechanisms	mechanism	NNS
cord-017161-lcqrd4v0	415	8	are	be	VBP
cord-017161-lcqrd4v0	415	9	activated	activate	VBN
cord-017161-lcqrd4v0	415	10	to	to	TO
cord-017161-lcqrd4v0	415	11	restore	restore	VB
cord-017161-lcqrd4v0	415	12	endothelium	endothelium	NN
cord-017161-lcqrd4v0	415	13	integrity	integrity	NN
cord-017161-lcqrd4v0	415	14	[	[	-LRB-
cord-017161-lcqrd4v0	415	15	232	232	CD
cord-017161-lcqrd4v0	415	16	]	]	-RRB-
cord-017161-lcqrd4v0	415	17	.	.	.
cord-017161-lcqrd4v0	416	1	In	in	IN
cord-017161-lcqrd4v0	416	2	the	the	DT
cord-017161-lcqrd4v0	416	3	past	past	NN
cord-017161-lcqrd4v0	416	4	,	,	,
cord-017161-lcqrd4v0	416	5	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	416	6	repair	repair	NN
cord-017161-lcqrd4v0	416	7	was	be	VBD
cord-017161-lcqrd4v0	416	8	considered	consider	VBN
cord-017161-lcqrd4v0	416	9	to	to	IN
cord-017161-lcqrd4v0	416	10	solely	solely	RB
cord-017161-lcqrd4v0	416	11	involve	involve	VB
cord-017161-lcqrd4v0	416	12	adjacent	adjacent	JJ
cord-017161-lcqrd4v0	416	13	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	416	14	cells	cell	NNS
cord-017161-lcqrd4v0	416	15	able	able	JJ
cord-017161-lcqrd4v0	416	16	to	to	TO
cord-017161-lcqrd4v0	416	17	replicate	replicate	VB
cord-017161-lcqrd4v0	416	18	locally	locally	RB
cord-017161-lcqrd4v0	416	19	and	and	CC
cord-017161-lcqrd4v0	416	20	replace	replace	VB
cord-017161-lcqrd4v0	416	21	the	the	DT
cord-017161-lcqrd4v0	416	22	lost	lost	JJ
cord-017161-lcqrd4v0	416	23	cells	cell	NNS
cord-017161-lcqrd4v0	416	24	.	.	.
cord-017161-lcqrd4v0	417	1	Since	since	IN
cord-017161-lcqrd4v0	417	2	the	the	DT
cord-017161-lcqrd4v0	417	3	original	original	JJ
cord-017161-lcqrd4v0	417	4	study	study	NN
cord-017161-lcqrd4v0	417	5	by	by	IN
cord-017161-lcqrd4v0	417	6	Asahara	Asahara	NNP
cord-017161-lcqrd4v0	417	7	et	et	NNP
cord-017161-lcqrd4v0	417	8	al	al	NNP
cord-017161-lcqrd4v0	417	9	.	.	NNP
cord-017161-lcqrd4v0	417	10	,	,	,
cord-017161-lcqrd4v0	417	11	it	-PRON-	PRP
cord-017161-lcqrd4v0	417	12	has	have	VBZ
cord-017161-lcqrd4v0	417	13	become	become	VBN
cord-017161-lcqrd4v0	417	14	obvious	obvious	JJ
cord-017161-lcqrd4v0	417	15	that	that	IN
cord-017161-lcqrd4v0	417	16	the	the	DT
cord-017161-lcqrd4v0	417	17	recruitment	recruitment	NN
cord-017161-lcqrd4v0	417	18	of	of	IN
cord-017161-lcqrd4v0	417	19	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	417	20	progenitor	progenitor	NN
cord-017161-lcqrd4v0	417	21	cells	cell	NNS
cord-017161-lcqrd4v0	417	22	(	(	-LRB-
cord-017161-lcqrd4v0	417	23	EPCs	epc	NNS
cord-017161-lcqrd4v0	417	24	)	)	-RRB-
cord-017161-lcqrd4v0	417	25	represents	represent	VBZ
cord-017161-lcqrd4v0	417	26	an	an	DT
cord-017161-lcqrd4v0	417	27	additional	additional	JJ
cord-017161-lcqrd4v0	417	28	mechanism	mechanism	NN
cord-017161-lcqrd4v0	417	29	for	for	IN
cord-017161-lcqrd4v0	417	30	vascular	vascular	JJ
cord-017161-lcqrd4v0	417	31	repair	repair	NN
cord-017161-lcqrd4v0	417	32	[	[	-LRB-
cord-017161-lcqrd4v0	417	33	232	232	CD
cord-017161-lcqrd4v0	417	34	]	]	-RRB-
cord-017161-lcqrd4v0	417	35	.	.	.
cord-017161-lcqrd4v0	418	1	These	these	DT
cord-017161-lcqrd4v0	418	2	stem	stem	NN
cord-017161-lcqrd4v0	418	3	cells	cell	NNS
cord-017161-lcqrd4v0	418	4	are	be	VBP
cord-017161-lcqrd4v0	418	5	mobilized	mobilize	VBN
cord-017161-lcqrd4v0	418	6	from	from	IN
cord-017161-lcqrd4v0	418	7	the	the	DT
cord-017161-lcqrd4v0	418	8	bone	bone	NN
cord-017161-lcqrd4v0	418	9	marrow	marrow	NN
cord-017161-lcqrd4v0	418	10	and	and	CC
cord-017161-lcqrd4v0	418	11	are	be	VBP
cord-017161-lcqrd4v0	418	12	able	able	JJ
cord-017161-lcqrd4v0	418	13	to	to	TO
cord-017161-lcqrd4v0	418	14	differentiate	differentiate	VB
cord-017161-lcqrd4v0	418	15	into	into	IN
cord-017161-lcqrd4v0	418	16	mature	mature	JJ
cord-017161-lcqrd4v0	418	17	cells	cell	NNS
cord-017161-lcqrd4v0	418	18	,	,	,
cord-017161-lcqrd4v0	418	19	restoring	restore	VBG
cord-017161-lcqrd4v0	418	20	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	418	21	integrity	integrity	NN
cord-017161-lcqrd4v0	418	22	at	at	IN
cord-017161-lcqrd4v0	418	23	sites	site	NNS
cord-017161-lcqrd4v0	418	24	of	of	IN
cord-017161-lcqrd4v0	418	25	vascular	vascular	JJ
cord-017161-lcqrd4v0	418	26	injury	injury	NN
cord-017161-lcqrd4v0	418	27	[	[	-LRB-
cord-017161-lcqrd4v0	418	28	232	232	CD
cord-017161-lcqrd4v0	418	29	]	]	-RRB-
cord-017161-lcqrd4v0	418	30	.	.	.
cord-017161-lcqrd4v0	419	1	This	this	DT
cord-017161-lcqrd4v0	419	2	spectrum	spectrum	NN
cord-017161-lcqrd4v0	419	3	of	of	IN
cord-017161-lcqrd4v0	419	4	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	419	5	responses	response	NNS
cord-017161-lcqrd4v0	419	6	can	can	MD
cord-017161-lcqrd4v0	419	7	be	be	VB
cord-017161-lcqrd4v0	419	8	considered	consider	VBN
cord-017161-lcqrd4v0	419	9	in	in	IN
cord-017161-lcqrd4v0	419	10	a	a	DT
cord-017161-lcqrd4v0	419	11	dynamic	dynamic	JJ
cord-017161-lcqrd4v0	419	12	triad	triad	NN
cord-017161-lcqrd4v0	419	13	"	"	''
cord-017161-lcqrd4v0	419	14	activation	activation	NN
cord-017161-lcqrd4v0	419	15	/	/	SYM
cord-017161-lcqrd4v0	419	16	injury/	injury/	CC
cord-017161-lcqrd4v0	419	17	repair	repair	NN
cord-017161-lcqrd4v0	419	18	"	"	''
cord-017161-lcqrd4v0	419	19	,	,	,
cord-017161-lcqrd4v0	419	20	which	which	WDT
cord-017161-lcqrd4v0	419	21	has	have	VBZ
cord-017161-lcqrd4v0	419	22	critically	critically	RB
cord-017161-lcqrd4v0	419	23	transformed	transform	VBN
cord-017161-lcqrd4v0	419	24	our	-PRON-	PRP$
cord-017161-lcqrd4v0	419	25	understanding	understanding	NN
cord-017161-lcqrd4v0	419	26	of	of	IN
cord-017161-lcqrd4v0	419	27	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	419	28	biology	biology	NN
cord-017161-lcqrd4v0	419	29	.	.	.
cord-017161-lcqrd4v0	420	1	CECs	CECs	NNP
cord-017161-lcqrd4v0	420	2	and	and	CC
cord-017161-lcqrd4v0	420	3	EMPs	emp	NNS
cord-017161-lcqrd4v0	420	4	are	be	VBP
cord-017161-lcqrd4v0	420	5	sensitive	sensitive	JJ
cord-017161-lcqrd4v0	420	6	biomarkers	biomarker	NNS
cord-017161-lcqrd4v0	420	7	of	of	IN
cord-017161-lcqrd4v0	420	8	vascular	vascular	JJ
cord-017161-lcqrd4v0	420	9	injury	injury	NN
cord-017161-lcqrd4v0	420	10	for	for	IN
cord-017161-lcqrd4v0	420	11	monitoring	monitor	VBG
cord-017161-lcqrd4v0	420	12	disease	disease	NN
cord-017161-lcqrd4v0	420	13	activity	activity	NN
cord-017161-lcqrd4v0	420	14	and	and	CC
cord-017161-lcqrd4v0	420	15	response	response	NN
cord-017161-lcqrd4v0	420	16	to	to	IN
cord-017161-lcqrd4v0	420	17	therapy	therapy	NN
cord-017161-lcqrd4v0	420	18	in	in	IN
cord-017161-lcqrd4v0	420	19	children	child	NNS
cord-017161-lcqrd4v0	420	20	with	with	IN
cord-017161-lcqrd4v0	420	21	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	420	22	[	[	-LRB-
cord-017161-lcqrd4v0	420	23	233	233	CD
cord-017161-lcqrd4v0	420	24	]	]	-RRB-
cord-017161-lcqrd4v0	420	25	.	.	.
cord-017161-lcqrd4v0	421	1	In	in	IN
cord-017161-lcqrd4v0	421	2	addition	addition	NN
cord-017161-lcqrd4v0	421	3	,	,	,
cord-017161-lcqrd4v0	421	4	preliminary	preliminary	JJ
cord-017161-lcqrd4v0	421	5	data	datum	NNS
cord-017161-lcqrd4v0	421	6	show	show	NN
cord-017161-lcqrd4v0	421	7	altered	alter	VBD
cord-017161-lcqrd4v0	421	8	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	421	9	repair	repair	NN
cord-017161-lcqrd4v0	421	10	responses	response	NNS
cord-017161-lcqrd4v0	421	11	in	in	IN
cord-017161-lcqrd4v0	421	12	children	child	NNS
cord-017161-lcqrd4v0	421	13	with	with	IN
cord-017161-lcqrd4v0	421	14	systemic	systemic	JJ
cord-017161-lcqrd4v0	421	15	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	421	16	,	,	,
cord-017161-lcqrd4v0	421	17	suggesting	suggest	VBG
cord-017161-lcqrd4v0	421	18	an	an	DT
cord-017161-lcqrd4v0	421	19	unfavourable	unfavourable	JJ
cord-017161-lcqrd4v0	421	20	balance	balance	NN
cord-017161-lcqrd4v0	421	21	of	of	IN
cord-017161-lcqrd4v0	421	22	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	421	23	injury	injury	NN
cord-017161-lcqrd4v0	421	24	and	and	CC
cord-017161-lcqrd4v0	421	25	repair	repair	NN
cord-017161-lcqrd4v0	421	26	in	in	IN
cord-017161-lcqrd4v0	421	27	childhood	childhood	NN
cord-017161-lcqrd4v0	421	28	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	421	29	[	[	-LRB-
cord-017161-lcqrd4v0	421	30	234	234	CD
cord-017161-lcqrd4v0	421	31	]	]	-RRB-
cord-017161-lcqrd4v0	421	32	.	.	.
cord-017161-lcqrd4v0	422	1	Several	several	JJ
cord-017161-lcqrd4v0	422	2	key	key	JJ
cord-017161-lcqrd4v0	422	3	aspects	aspect	NNS
cord-017161-lcqrd4v0	422	4	of	of	IN
cord-017161-lcqrd4v0	422	5	the	the	DT
cord-017161-lcqrd4v0	422	6	long	long	JJ
cord-017161-lcqrd4v0	422	7	-	-	HYPH
cord-017161-lcqrd4v0	422	8	term	term	NN
cord-017161-lcqrd4v0	422	9	outcome	outcome	NN
cord-017161-lcqrd4v0	422	10	of	of	IN
cord-017161-lcqrd4v0	422	11	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	422	12	in	in	IN
cord-017161-lcqrd4v0	422	13	the	the	DT
cord-017161-lcqrd4v0	422	14	young	young	JJ
cord-017161-lcqrd4v0	422	15	remain	remain	VBP
cord-017161-lcqrd4v0	422	16	of	of	IN
cord-017161-lcqrd4v0	422	17	ongoing	ongoing	JJ
cord-017161-lcqrd4v0	422	18	concern	concern	NN
cord-017161-lcqrd4v0	422	19	.	.	.
cord-017161-lcqrd4v0	423	1	Histological	Histological	NNP
cord-017161-lcqrd4v0	423	2	fi	fi	IN
cord-017161-lcqrd4v0	423	3	ndings	nding	NNS
cord-017161-lcqrd4v0	423	4	seen	see	VBN
cord-017161-lcqrd4v0	423	5	in	in	IN
cord-017161-lcqrd4v0	423	6	KD	KD	NNP
cord-017161-lcqrd4v0	423	7	arteries	artery	NNS
cord-017161-lcqrd4v0	423	8	at	at	IN
cord-017161-lcqrd4v0	423	9	sites	site	NNS
cord-017161-lcqrd4v0	423	10	of	of	IN
cord-017161-lcqrd4v0	423	11	previous	previous	JJ
cord-017161-lcqrd4v0	423	12	aneurysmal	aneurysmal	JJ
cord-017161-lcqrd4v0	423	13	lesions	lesion	NNS
cord-017161-lcqrd4v0	423	14	long	long	RB
cord-017161-lcqrd4v0	423	15	after	after	IN
cord-017161-lcqrd4v0	423	16	disease	disease	NN
cord-017161-lcqrd4v0	423	17	resolution	resolution	NN
cord-017161-lcqrd4v0	423	18	appear	appear	VBP
cord-017161-lcqrd4v0	423	19	to	to	TO
cord-017161-lcqrd4v0	423	20	be	be	VB
cord-017161-lcqrd4v0	423	21	indistinguishable	indistinguishable	JJ
cord-017161-lcqrd4v0	423	22	from	from	IN
cord-017161-lcqrd4v0	423	23	atherosclerosis	atherosclerosis	NN
cord-017161-lcqrd4v0	423	24	[	[	-LRB-
cord-017161-lcqrd4v0	423	25	235	235	CD
cord-017161-lcqrd4v0	423	26	]	]	-RRB-
cord-017161-lcqrd4v0	423	27	.	.	.
cord-017161-lcqrd4v0	424	1	Dhillon	Dhillon	NNP
cord-017161-lcqrd4v0	424	2	et	et	NNP
cord-017161-lcqrd4v0	424	3	al	al	NNP
cord-017161-lcqrd4v0	424	4	.	.	NNP
cord-017161-lcqrd4v0	424	5	studied	study	VBD
cord-017161-lcqrd4v0	424	6	vascular	vascular	JJ
cord-017161-lcqrd4v0	424	7	responses	response	NNS
cord-017161-lcqrd4v0	424	8	to	to	IN
cord-017161-lcqrd4v0	424	9	reactive	reactive	JJ
cord-017161-lcqrd4v0	424	10	hyperemia	hyperemia	NN
cord-017161-lcqrd4v0	424	11	in	in	IN
cord-017161-lcqrd4v0	424	12	the	the	DT
cord-017161-lcqrd4v0	424	13	brachial	brachial	JJ
cord-017161-lcqrd4v0	424	14	artery	artery	NN
cord-017161-lcqrd4v0	424	15	using	use	VBG
cord-017161-lcqrd4v0	424	16	high	high	JJ
cord-017161-lcqrd4v0	424	17	-	-	HYPH
cord-017161-lcqrd4v0	424	18	resolution	resolution	NN
cord-017161-lcqrd4v0	424	19	ultrasound	ultrasound	NN
cord-017161-lcqrd4v0	424	20	[	[	-LRB-
cord-017161-lcqrd4v0	424	21	106	106	CD
cord-017161-lcqrd4v0	424	22	]	]	-RRB-
cord-017161-lcqrd4v0	424	23	.	.	.
cord-017161-lcqrd4v0	425	1	Flow	flow	NN
cord-017161-lcqrd4v0	425	2	-	-	HYPH
cord-017161-lcqrd4v0	425	3	mediated	mediate	VBN
cord-017161-lcqrd4v0	425	4	dilation	dilation	NN
cord-017161-lcqrd4v0	425	5	(	(	-LRB-
cord-017161-lcqrd4v0	425	6	an	an	DT
cord-017161-lcqrd4v0	425	7	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	425	8	-	-	HYPH
cord-017161-lcqrd4v0	425	9	dependent	dependent	JJ
cord-017161-lcqrd4v0	425	10	response	response	NN
cord-017161-lcqrd4v0	425	11	)	)	-RRB-
cord-017161-lcqrd4v0	425	12	was	be	VBD
cord-017161-lcqrd4v0	425	13	reduced	reduce	VBN
cord-017161-lcqrd4v0	425	14	in	in	IN
cord-017161-lcqrd4v0	425	15	KD	KD	NNP
cord-017161-lcqrd4v0	425	16	patients	patient	NNS
cord-017161-lcqrd4v0	425	17	compared	compare	VBN
cord-017161-lcqrd4v0	425	18	with	with	IN
cord-017161-lcqrd4v0	425	19	control	control	NN
cord-017161-lcqrd4v0	425	20	subjects	subject	NNS
cord-017161-lcqrd4v0	425	21	many	many	JJ
cord-017161-lcqrd4v0	425	22	years	year	NNS
cord-017161-lcqrd4v0	425	23	after	after	IN
cord-017161-lcqrd4v0	425	24	the	the	DT
cord-017161-lcqrd4v0	425	25	illness	illness	NN
cord-017161-lcqrd4v0	425	26	,	,	,
cord-017161-lcqrd4v0	425	27	even	even	RB
cord-017161-lcqrd4v0	425	28	in	in	IN
cord-017161-lcqrd4v0	425	29	patients	patient	NNS
cord-017161-lcqrd4v0	425	30	without	without	IN
cord-017161-lcqrd4v0	425	31	detectable	detectable	JJ
cord-017161-lcqrd4v0	425	32	early	early	JJ
cord-017161-lcqrd4v0	425	33	coronary	coronary	JJ
cord-017161-lcqrd4v0	425	34	artery	artery	NN
cord-017161-lcqrd4v0	425	35	involvement	involvement	NN
cord-017161-lcqrd4v0	425	36	.	.	.
cord-017161-lcqrd4v0	426	1	In	in	IN
cord-017161-lcqrd4v0	426	2	addition	addition	NN
cord-017161-lcqrd4v0	426	3	,	,	,
cord-017161-lcqrd4v0	426	4	Cheung	Cheung	NNP
cord-017161-lcqrd4v0	426	5	et	et	NNP
cord-017161-lcqrd4v0	426	6	al	al	NNP
cord-017161-lcqrd4v0	426	7	.	.	.
cord-017161-lcqrd4v0	426	8	studied	study	VBD
cord-017161-lcqrd4v0	426	9	a	a	DT
cord-017161-lcqrd4v0	426	10	cohort	cohort	NN
cord-017161-lcqrd4v0	426	11	of	of	IN
cord-017161-lcqrd4v0	426	12	patients	patient	NNS
cord-017161-lcqrd4v0	426	13	with	with	IN
cord-017161-lcqrd4v0	426	14	KD	KD	NNP
cord-017161-lcqrd4v0	426	15	with	with	IN
cord-017161-lcqrd4v0	426	16	or	or	CC
cord-017161-lcqrd4v0	426	17	without	without	IN
cord-017161-lcqrd4v0	426	18	coronary	coronary	JJ
cord-017161-lcqrd4v0	426	19	aneurysms	aneurysm	NNS
cord-017161-lcqrd4v0	426	20	compared	compare	VBN
cord-017161-lcqrd4v0	426	21	to	to	IN
cord-017161-lcqrd4v0	426	22	healthy	healthy	JJ
cord-017161-lcqrd4v0	426	23	controls	control	NNS
cord-017161-lcqrd4v0	426	24	and	and	CC
cord-017161-lcqrd4v0	426	25	demonstrated	demonstrate	VBD
cord-017161-lcqrd4v0	426	26	reduced	reduced	JJ
cord-017161-lcqrd4v0	426	27	arterial	arterial	JJ
cord-017161-lcqrd4v0	426	28	distensibility	distensibility	NN
cord-017161-lcqrd4v0	426	29	(	(	-LRB-
cord-017161-lcqrd4v0	426	30	an	an	DT
cord-017161-lcqrd4v0	426	31	independent	independent	JJ
cord-017161-lcqrd4v0	426	32	risk	risk	NN
cord-017161-lcqrd4v0	426	33	factor	factor	NN
cord-017161-lcqrd4v0	426	34	for	for	IN
cord-017161-lcqrd4v0	426	35	cardiovascular	cardiovascular	JJ
cord-017161-lcqrd4v0	426	36	morbidity	morbidity	NN
cord-017161-lcqrd4v0	426	37	and	and	CC
cord-017161-lcqrd4v0	426	38	mortality	mortality	NN
cord-017161-lcqrd4v0	426	39	in	in	IN
cord-017161-lcqrd4v0	426	40	adults	adult	NNS
cord-017161-lcqrd4v0	426	41	)	)	-RRB-
cord-017161-lcqrd4v0	426	42	,	,	,
cord-017161-lcqrd4v0	426	43	as	as	IN
cord-017161-lcqrd4v0	426	44	assessed	assess	VBN
cord-017161-lcqrd4v0	426	45	using	use	VBG
cord-017161-lcqrd4v0	426	46	ultrasound	ultrasound	NN
cord-017161-lcqrd4v0	426	47	pulse	pulse	NN
cord-017161-lcqrd4v0	426	48	wave	wave	NN
cord-017161-lcqrd4v0	426	49	velocity	velocity	NN
cord-017161-lcqrd4v0	426	50	in	in	IN
cord-017161-lcqrd4v0	426	51	the	the	DT
cord-017161-lcqrd4v0	426	52	brachio	brachio	JJ
cord-017161-lcqrd4v0	426	53	-	-	HYPH
cord-017161-lcqrd4v0	426	54	radial	radial	JJ
cord-017161-lcqrd4v0	426	55	arterial	arterial	JJ
cord-017161-lcqrd4v0	426	56	segments	segment	NNS
cord-017161-lcqrd4v0	426	57	and	and	CC
cord-017161-lcqrd4v0	426	58	carotid	carotid	JJ
cord-017161-lcqrd4v0	426	59	IMT	IMT	NNP
cord-017161-lcqrd4v0	426	60	[	[	-LRB-
cord-017161-lcqrd4v0	426	61	236	236	CD
cord-017161-lcqrd4v0	426	62	]	]	-RRB-
cord-017161-lcqrd4v0	426	63	.	.	.
cord-017161-lcqrd4v0	427	1	Similar	similar	JJ
cord-017161-lcqrd4v0	427	2	fi	fi	IN
cord-017161-lcqrd4v0	427	3	ndings	nding	NNS
cord-017161-lcqrd4v0	427	4	have	have	VBP
cord-017161-lcqrd4v0	427	5	also	also	RB
cord-017161-lcqrd4v0	427	6	been	be	VBN
cord-017161-lcqrd4v0	427	7	documented	document	VBN
cord-017161-lcqrd4v0	427	8	in	in	IN
cord-017161-lcqrd4v0	427	9	children	child	NNS
cord-017161-lcqrd4v0	427	10	with	with	IN
cord-017161-lcqrd4v0	427	11	PAN	PAN	NNP
cord-017161-lcqrd4v0	427	12	[	[	-LRB-
cord-017161-lcqrd4v0	427	13	237	237	CD
cord-017161-lcqrd4v0	427	14	]	]	-RRB-
cord-017161-lcqrd4v0	427	15	.	.	.
cord-017161-lcqrd4v0	428	1	Thus	thus	RB
cord-017161-lcqrd4v0	428	2	,	,	,
cord-017161-lcqrd4v0	428	3	the	the	DT
cord-017161-lcqrd4v0	428	4	longterm	longterm	JJ
cord-017161-lcqrd4v0	428	5	outlook	outlook	NN
cord-017161-lcqrd4v0	428	6	for	for	IN
cord-017161-lcqrd4v0	428	7	patients	patient	NNS
cord-017161-lcqrd4v0	428	8	with	with	IN
cord-017161-lcqrd4v0	428	9	systemic	systemic	JJ
cord-017161-lcqrd4v0	428	10	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	428	11	must	must	MD
cord-017161-lcqrd4v0	428	12	remain	remain	VB
cord-017161-lcqrd4v0	428	13	guarded	guard	VBN
cord-017161-lcqrd4v0	428	14	at	at	IN
cord-017161-lcqrd4v0	428	15	the	the	DT
cord-017161-lcqrd4v0	428	16	present	present	JJ
cord-017161-lcqrd4v0	428	17	time	time	NN
cord-017161-lcqrd4v0	428	18	.	.	.
cord-017161-lcqrd4v0	429	1	A	a	DT
cord-017161-lcqrd4v0	429	2	series	series	NN
cord-017161-lcqrd4v0	429	3	of	of	IN
cord-017161-lcqrd4v0	429	4	signi	signi	NNP
cord-017161-lcqrd4v0	429	5	fi	fi	NNP
cord-017161-lcqrd4v0	429	6	ca	can	MD
cord-017161-lcqrd4v0	429	7	nt	not	RB
cord-017161-lcqrd4v0	429	8	short	short	JJ
cord-017161-lcqrd4v0	429	9	-	-	HYPH
cord-017161-lcqrd4v0	429	10	and	and	CC
cord-017161-lcqrd4v0	429	11	long	long	JJ
cord-017161-lcqrd4v0	429	12	-	-	HYPH
cord-017161-lcqrd4v0	429	13	term	term	NN
cord-017161-lcqrd4v0	429	14	challenges	challenge	NNS
cord-017161-lcqrd4v0	429	15	are	be	VBP
cord-017161-lcqrd4v0	429	16	looming	loom	VBG
cord-017161-lcqrd4v0	429	17	in	in	IN
cord-017161-lcqrd4v0	429	18	the	the	DT
cord-017161-lcqrd4v0	429	19	fi	fi	NNP
cord-017161-lcqrd4v0	429	20	eld	eld	NN
cord-017161-lcqrd4v0	429	21	of	of	IN
cord-017161-lcqrd4v0	429	22	paediatric	paediatric	JJ
cord-017161-lcqrd4v0	429	23	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	429	24	research	research	NN
cord-017161-lcqrd4v0	429	25	.	.	.
cord-017161-lcqrd4v0	430	1	The	the	DT
cord-017161-lcqrd4v0	430	2	development	development	NN
cord-017161-lcqrd4v0	430	3	of	of	IN
cord-017161-lcqrd4v0	430	4	biomarkers	biomarker	NNS
cord-017161-lcqrd4v0	430	5	that	that	WDT
cord-017161-lcqrd4v0	430	6	allow	allow	VBP
cord-017161-lcqrd4v0	430	7	reliable	reliable	JJ
cord-017161-lcqrd4v0	430	8	non	non	JJ
cord-017161-lcqrd4v0	430	9	-	-	JJ
cord-017161-lcqrd4v0	430	10	invasive	invasive	JJ
cord-017161-lcqrd4v0	430	11	monitoring	monitoring	NN
cord-017161-lcqrd4v0	430	12	of	of	IN
cord-017161-lcqrd4v0	430	13	disease	disease	NN
cord-017161-lcqrd4v0	430	14	activity	activity	NN
cord-017161-lcqrd4v0	430	15	and	and	CC
cord-017161-lcqrd4v0	430	16	guide	guide	VB
cord-017161-lcqrd4v0	430	17	therapeutic	therapeutic	JJ
cord-017161-lcqrd4v0	430	18	decisions	decision	NNS
cord-017161-lcqrd4v0	430	19	is	be	VBZ
cord-017161-lcqrd4v0	430	20	of	of	IN
cord-017161-lcqrd4v0	430	21	great	great	JJ
cord-017161-lcqrd4v0	430	22	clinical	clinical	JJ
cord-017161-lcqrd4v0	430	23	importance	importance	NN
cord-017161-lcqrd4v0	430	24	[	[	-LRB-
cord-017161-lcqrd4v0	430	25	233	233	CD
cord-017161-lcqrd4v0	430	26	,	,	,
cord-017161-lcqrd4v0	430	27	238	238	CD
cord-017161-lcqrd4v0	430	28	]	]	-RRB-
cord-017161-lcqrd4v0	430	29	.	.	.
cord-017161-lcqrd4v0	431	1	Furthermore	furthermore	RB
cord-017161-lcqrd4v0	431	2	,	,	,
cord-017161-lcqrd4v0	431	3	several	several	JJ
cord-017161-lcqrd4v0	431	4	key	key	JJ
cord-017161-lcqrd4v0	431	5	aspects	aspect	NNS
cord-017161-lcqrd4v0	431	6	of	of	IN
cord-017161-lcqrd4v0	431	7	the	the	DT
cord-017161-lcqrd4v0	431	8	longterm	longterm	JJ
cord-017161-lcqrd4v0	431	9	cardiovascular	cardiovascular	JJ
cord-017161-lcqrd4v0	431	10	risk	risk	NN
cord-017161-lcqrd4v0	431	11	for	for	IN
cord-017161-lcqrd4v0	431	12	children	child	NNS
cord-017161-lcqrd4v0	431	13	who	who	WP
cord-017161-lcqrd4v0	431	14	have	have	VBP
cord-017161-lcqrd4v0	431	15	systemic	systemic	JJ
cord-017161-lcqrd4v0	431	16	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	431	17	are	be	VBP
cord-017161-lcqrd4v0	431	18	described	describe	VBN
cord-017161-lcqrd4v0	431	19	[	[	-LRB-
cord-017161-lcqrd4v0	431	20	239	239	CD
cord-017161-lcqrd4v0	431	21	]	]	-RRB-
cord-017161-lcqrd4v0	431	22	.	.	.
cord-017161-lcqrd4v0	432	1	The	the	DT
cord-017161-lcqrd4v0	432	2	emergence	emergence	NN
cord-017161-lcqrd4v0	432	3	of	of	IN
cord-017161-lcqrd4v0	432	4	new	new	JJ
cord-017161-lcqrd4v0	432	5	therapies	therapy	NNS
cord-017161-lcqrd4v0	432	6	for	for	IN
cord-017161-lcqrd4v0	432	7	the	the	DT
cord-017161-lcqrd4v0	432	8	treatment	treatment	NN
cord-017161-lcqrd4v0	432	9	of	of	IN
cord-017161-lcqrd4v0	432	10	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	432	11	in	in	IN
cord-017161-lcqrd4v0	432	12	children	child	NNS
cord-017161-lcqrd4v0	432	13	provides	provide	VBZ
cord-017161-lcqrd4v0	432	14	a	a	DT
cord-017161-lcqrd4v0	432	15	real	real	JJ
cord-017161-lcqrd4v0	432	16	opportunity	opportunity	NN
cord-017161-lcqrd4v0	432	17	to	to	TO
cord-017161-lcqrd4v0	432	18	limit	limit	VB
cord-017161-lcqrd4v0	432	19	cyclophosphamide	cyclophosphamide	NN
cord-017161-lcqrd4v0	432	20	and	and	CC
cord-017161-lcqrd4v0	432	21	corticosteroid	corticosteroid	NN
cord-017161-lcqrd4v0	432	22	exposure	exposure	NN
cord-017161-lcqrd4v0	432	23	in	in	IN
cord-017161-lcqrd4v0	432	24	the	the	DT
cord-017161-lcqrd4v0	432	25	young	young	JJ
cord-017161-lcqrd4v0	432	26	.	.	.
cord-017161-lcqrd4v0	433	1	These	these	DT
cord-017161-lcqrd4v0	433	2	include	include	VBP
cord-017161-lcqrd4v0	433	3	MMF	MMF	NNP
cord-017161-lcqrd4v0	433	4	[	[	-LRB-
cord-017161-lcqrd4v0	433	5	182	182	CD
cord-017161-lcqrd4v0	433	6	,	,	,
cord-017161-lcqrd4v0	433	7	183	183	CD
cord-017161-lcqrd4v0	433	8	,	,	,
cord-017161-lcqrd4v0	433	9	240	240	CD
cord-017161-lcqrd4v0	433	10	,	,	,
cord-017161-lcqrd4v0	433	11	241	241	CD
cord-017161-lcqrd4v0	433	12	]	]	-RRB-
cord-017161-lcqrd4v0	433	13	and	and	CC
cord-017161-lcqrd4v0	433	14	biologic	biologic	JJ
cord-017161-lcqrd4v0	433	15	agents	agent	NNS
cord-017161-lcqrd4v0	433	16	such	such	JJ
cord-017161-lcqrd4v0	433	17	as	as	IN
cord-017161-lcqrd4v0	433	18	rituximab	rituximab	NN
cord-017161-lcqrd4v0	433	19	[	[	-LRB-
cord-017161-lcqrd4v0	433	20	184	184	CD
cord-017161-lcqrd4v0	433	21	,	,	,
cord-017161-lcqrd4v0	433	22	185	185	CD
cord-017161-lcqrd4v0	433	23	,	,	,
cord-017161-lcqrd4v0	433	24	187	187	CD
cord-017161-lcqrd4v0	433	25	]	]	-RRB-
cord-017161-lcqrd4v0	433	26	,	,	,
cord-017161-lcqrd4v0	433	27	anti	anti	JJ
cord-017161-lcqrd4v0	433	28	-	-	JJ
cord-017161-lcqrd4v0	433	29	TNF	TNF	NNP
cord-017161-lcqrd4v0	433	30	-	-	,
cord-017161-lcqrd4v0	433	31	a	a	DT
cord-017161-lcqrd4v0	433	32	[	[	-LRB-
cord-017161-lcqrd4v0	433	33	187	187	CD
cord-017161-lcqrd4v0	433	34	,	,	,
cord-017161-lcqrd4v0	433	35	242	242	CD
cord-017161-lcqrd4v0	433	36	]	]	-RRB-
cord-017161-lcqrd4v0	433	37	and	and	CC
cord-017161-lcqrd4v0	433	38	thalidomide	thalidomide	NN
cord-017161-lcqrd4v0	433	39	analogues	analogue	NNS
cord-017161-lcqrd4v0	433	40	such	such	JJ
cord-017161-lcqrd4v0	433	41	as	as	IN
cord-017161-lcqrd4v0	433	42	lenalidomide	lenalidomide	NN
cord-017161-lcqrd4v0	433	43	[	[	-LRB-
cord-017161-lcqrd4v0	433	44	243	243	CD
cord-017161-lcqrd4v0	433	45	]	]	-RRB-
cord-017161-lcqrd4v0	433	46	,	,	,
cord-017161-lcqrd4v0	433	47	amongst	amongst	IN
cord-017161-lcqrd4v0	433	48	others	other	NNS
cord-017161-lcqrd4v0	433	49	.	.	.
cord-017161-lcqrd4v0	434	1	None	none	NN
cord-017161-lcqrd4v0	434	2	of	of	IN
cord-017161-lcqrd4v0	434	3	these	these	DT
cord-017161-lcqrd4v0	434	4	agents	agent	NNS
cord-017161-lcqrd4v0	434	5	yet	yet	RB
cord-017161-lcqrd4v0	434	6	has	have	VBZ
cord-017161-lcqrd4v0	434	7	an	an	DT
cord-017161-lcqrd4v0	434	8	evidence	evidence	NN
cord-017161-lcqrd4v0	434	9	base	base	NN
cord-017161-lcqrd4v0	434	10	to	to	TO
cord-017161-lcqrd4v0	434	11	justify	justify	VB
cord-017161-lcqrd4v0	434	12	their	-PRON-	PRP$
cord-017161-lcqrd4v0	434	13	routine	routine	JJ
cord-017161-lcqrd4v0	434	14	use	use	NN
cord-017161-lcqrd4v0	434	15	in	in	IN
cord-017161-lcqrd4v0	434	16	paediatric	paediatric	JJ
cord-017161-lcqrd4v0	434	17	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	434	18	,	,	,
cord-017161-lcqrd4v0	434	19	although	although	IN
cord-017161-lcqrd4v0	434	20	many	many	JJ
cord-017161-lcqrd4v0	434	21	are	be	VBP
cord-017161-lcqrd4v0	434	22	increasingly	increasingly	RB
cord-017161-lcqrd4v0	434	23	used	use	VBN
cord-017161-lcqrd4v0	434	24	in	in	IN
cord-017161-lcqrd4v0	434	25	this	this	DT
cord-017161-lcqrd4v0	434	26	context	context	NN
cord-017161-lcqrd4v0	434	27	in	in	IN
cord-017161-lcqrd4v0	434	28	individual	individual	JJ
cord-017161-lcqrd4v0	434	29	cases	case	NNS
cord-017161-lcqrd4v0	434	30	.	.	.
cord-017161-lcqrd4v0	435	1	It	-PRON-	PRP
cord-017161-lcqrd4v0	435	2	is	be	VBZ
cord-017161-lcqrd4v0	435	3	likely	likely	JJ
cord-017161-lcqrd4v0	435	4	that	that	IN
cord-017161-lcqrd4v0	435	5	in	in	IN
cord-017161-lcqrd4v0	435	6	the	the	DT
cord-017161-lcqrd4v0	435	7	future	future	JJ
cord-017161-lcqrd4v0	435	8	clinical	clinical	JJ
cord-017161-lcqrd4v0	435	9	trials	trial	NNS
cord-017161-lcqrd4v0	435	10	in	in	IN
cord-017161-lcqrd4v0	435	11	the	the	DT
cord-017161-lcqrd4v0	435	12	young	young	JJ
cord-017161-lcqrd4v0	435	13	will	will	MD
cord-017161-lcqrd4v0	435	14	attempt	attempt	VB
cord-017161-lcqrd4v0	435	15	to	to	TO
cord-017161-lcqrd4v0	435	16	focus	focus	VB
cord-017161-lcqrd4v0	435	17	on	on	IN
cord-017161-lcqrd4v0	435	18	these	these	DT
cord-017161-lcqrd4v0	435	19	agents	agent	NNS
cord-017161-lcqrd4v0	435	20	as	as	IN
cord-017161-lcqrd4v0	435	21	alternatives	alternative	NNS
cord-017161-lcqrd4v0	435	22	to	to	IN
cord-017161-lcqrd4v0	435	23	cyclophosphamide	cyclophosphamide	NN
cord-017161-lcqrd4v0	435	24	and	and	CC
cord-017161-lcqrd4v0	435	25	azathioprine	azathioprine	NN
cord-017161-lcqrd4v0	435	26	for	for	IN
cord-017161-lcqrd4v0	435	27	induction	induction	NN
cord-017161-lcqrd4v0	435	28	of	of	IN
cord-017161-lcqrd4v0	435	29	and/or	and/or	CC
cord-017161-lcqrd4v0	435	30	maintenance	maintenance	NN
cord-017161-lcqrd4v0	435	31	of	of	IN
cord-017161-lcqrd4v0	435	32	remission	remission	NN
cord-017161-lcqrd4v0	435	33	of	of	IN
cord-017161-lcqrd4v0	435	34	systemic	systemic	JJ
cord-017161-lcqrd4v0	435	35	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	435	36	.	.	.
cord-017161-lcqrd4v0	436	1	These	these	DT
cord-017161-lcqrd4v0	436	2	sorts	sort	NNS
cord-017161-lcqrd4v0	436	3	of	of	IN
cord-017161-lcqrd4v0	436	4	trials	trial	NNS
cord-017161-lcqrd4v0	436	5	will	will	MD
cord-017161-lcqrd4v0	436	6	require	require	VB
cord-017161-lcqrd4v0	436	7	international	international	JJ
cord-017161-lcqrd4v0	436	8	collaboration	collaboration	NN
cord-017161-lcqrd4v0	436	9	if	if	IN
cord-017161-lcqrd4v0	436	10	meaningful	meaningful	JJ
cord-017161-lcqrd4v0	436	11	patient	patient	JJ
cord-017161-lcqrd4v0	436	12	numbers	number	NNS
cord-017161-lcqrd4v0	436	13	are	be	VBP
cord-017161-lcqrd4v0	436	14	to	to	TO
cord-017161-lcqrd4v0	436	15	be	be	VB
cord-017161-lcqrd4v0	436	16	realized	realize	VBN
cord-017161-lcqrd4v0	436	17	,	,	,
cord-017161-lcqrd4v0	436	18	and	and	CC
cord-017161-lcqrd4v0	436	19	this	this	DT
cord-017161-lcqrd4v0	436	20	remains	remain	VBZ
cord-017161-lcqrd4v0	436	21	an	an	DT
cord-017161-lcqrd4v0	436	22	important	important	JJ
cord-017161-lcqrd4v0	436	23	challenge	challenge	NN
cord-017161-lcqrd4v0	436	24	for	for	IN
cord-017161-lcqrd4v0	436	25	vasculitis	vasculitis	JJ
cord-017161-lcqrd4v0	436	26	research	research	NN
cord-017161-lcqrd4v0	436	27	in	in	IN
cord-017161-lcqrd4v0	436	28	children	child	NNS
cord-017161-lcqrd4v0	436	29	.	.	.
cord-017161-lcqrd4v0	437	1	Vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	437	2	from	from	IN
cord-017161-lcqrd4v0	437	3	the	the	DT
cord-017161-lcqrd4v0	437	4	pediatric	pediatric	JJ
cord-017161-lcqrd4v0	437	5	perspective	perspective	NN
cord-017161-lcqrd4v0	437	6	Incidence	incidence	NN
cord-017161-lcqrd4v0	437	7	of	of	IN
cord-017161-lcqrd4v0	437	8	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	437	9	-	-	HYPH
cord-017161-lcqrd4v0	437	10	Schonlein	Schonlein	NNP
cord-017161-lcqrd4v0	437	11	purpura	purpura	NN
cord-017161-lcqrd4v0	437	12	,	,	,
cord-017161-lcqrd4v0	437	13	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	437	14	disease	disease	NN
cord-017161-lcqrd4v0	437	15	,	,	,
cord-017161-lcqrd4v0	437	16	and	and	CC
cord-017161-lcqrd4v0	437	17	rare	rare	JJ
cord-017161-lcqrd4v0	437	18	vasculitides	vasculitide	NNS
cord-017161-lcqrd4v0	437	19	in	in	IN
cord-017161-lcqrd4v0	437	20	children	child	NNS
cord-017161-lcqrd4v0	437	21	of	of	IN
cord-017161-lcqrd4v0	437	22	different	different	JJ
cord-017161-lcqrd4v0	437	23	ethnic	ethnic	JJ
cord-017161-lcqrd4v0	437	24	origins	origin	NNS
cord-017161-lcqrd4v0	438	1	Vasculitis	vasculitis	JJ
cord-017161-lcqrd4v0	438	2	treatment	treatment	NN
cord-017161-lcqrd4v0	438	3	-	-	HYPH
cord-017161-lcqrd4v0	438	4	new	new	JJ
cord-017161-lcqrd4v0	438	5	therapeutic	therapeutic	JJ
cord-017161-lcqrd4v0	438	6	approaches	approach	NNS
cord-017161-lcqrd4v0	439	1	What	what	WP
cord-017161-lcqrd4v0	439	2	's	be	VBZ
cord-017161-lcqrd4v0	439	3	new	new	JJ
cord-017161-lcqrd4v0	439	4	in	in	IN
cord-017161-lcqrd4v0	439	5	the	the	DT
cord-017161-lcqrd4v0	439	6	aetiopathogenesis	aetiopathogenesis	NN
cord-017161-lcqrd4v0	439	7	of	of	IN
cord-017161-lcqrd4v0	439	8	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	439	9	?	?	.
cord-017161-lcqrd4v0	440	1	The	the	DT
cord-017161-lcqrd4v0	440	2	other	other	JJ
cord-017161-lcqrd4v0	440	3	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	440	4	syndromes	syndrome	NNS
cord-017161-lcqrd4v0	440	5	and	and	CC
cord-017161-lcqrd4v0	440	6	kidney	kidney	NN
cord-017161-lcqrd4v0	440	7	involvement	involvement	NN
cord-017161-lcqrd4v0	440	8	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	440	9	-	-	HYPH
cord-017161-lcqrd4v0	440	10	Schonlein	Schonlein	NNP
cord-017161-lcqrd4v0	440	11	purpura	purpura	NN
cord-017161-lcqrd4v0	440	12	EULAR	EULAR	NNP
cord-017161-lcqrd4v0	440	13	/	/	SYM
cord-017161-lcqrd4v0	440	14	PReS	PReS	NNP
cord-017161-lcqrd4v0	440	15	endorsed	endorse	VBD
cord-017161-lcqrd4v0	440	16	consensus	consensus	NN
cord-017161-lcqrd4v0	440	17	criteria	criterion	NNS
cord-017161-lcqrd4v0	440	18	for	for	IN
cord-017161-lcqrd4v0	440	19	the	the	DT
cord-017161-lcqrd4v0	440	20	classi	classi	NNP
cord-017161-lcqrd4v0	440	21	fi	fi	NNP
cord-017161-lcqrd4v0	440	22	cation	cation	NNP
cord-017161-lcqrd4v0	440	23	of	of	IN
cord-017161-lcqrd4v0	440	24	childhood	childhood	NN
cord-017161-lcqrd4v0	440	25	vasculitides	vasculitide	VBZ
cord-017161-lcqrd4v0	440	26	EULAR	EULAR	NNP
cord-017161-lcqrd4v0	440	27	/	/	SYM
cord-017161-lcqrd4v0	440	28	PRINTO	PRINTO	NNP
cord-017161-lcqrd4v0	440	29	/	/	SYM
cord-017161-lcqrd4v0	440	30	PRES	PRES	NNP
cord-017161-lcqrd4v0	440	31	criteria	criterion	NNS
cord-017161-lcqrd4v0	440	32	for	for	IN
cord-017161-lcqrd4v0	440	33	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	440	34	Schonlein	Schonlein	NNP
cord-017161-lcqrd4v0	440	35	purpura	purpura	NN
cord-017161-lcqrd4v0	440	36	,	,	,
cord-017161-lcqrd4v0	440	37	childhood	childhood	NN
cord-017161-lcqrd4v0	440	38	polyarteritis	polyarteritis	NN
cord-017161-lcqrd4v0	440	39	nodosa	nodosa	NNP
cord-017161-lcqrd4v0	440	40	,	,	,
cord-017161-lcqrd4v0	440	41	childhood	childhood	NN
cord-017161-lcqrd4v0	440	42	Wegener	Wegener	NNP
cord-017161-lcqrd4v0	440	43	granulomatosis	granulomatosis	NN
cord-017161-lcqrd4v0	440	44	and	and	CC
cord-017161-lcqrd4v0	441	1	childhood	childhood	NN
cord-017161-lcqrd4v0	441	2	Takayasu	Takayasu	NNP
cord-017161-lcqrd4v0	441	3	arteritis	arteritis	NN
cord-017161-lcqrd4v0	441	4	:	:	:
cord-017161-lcqrd4v0	441	5	Ankara	Ankara	NNP
cord-017161-lcqrd4v0	441	6	2008	2008	CD
cord-017161-lcqrd4v0	441	7	.	.	.
cord-017161-lcqrd4v0	442	1	Part	part	NN
cord-017161-lcqrd4v0	442	2	II	ii	CD
cord-017161-lcqrd4v0	443	1	:	:	:
cord-017161-lcqrd4v0	443	2	fi	fi	NNP
cord-017161-lcqrd4v0	444	1	nal	nal	NNP
cord-017161-lcqrd4v0	444	2	classi	classi	FW
cord-017161-lcqrd4v0	444	3	fi	fi	NNP
cord-017161-lcqrd4v0	444	4	cation	cation	NNP
cord-017161-lcqrd4v0	444	5	criteria	criterion	NNS
cord-017161-lcqrd4v0	445	1	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	445	2	Schönlein	Schönlein	NNP
cord-017161-lcqrd4v0	445	3	purpura	purpura	NN
cord-017161-lcqrd4v0	445	4	in	in	IN
cord-017161-lcqrd4v0	445	5	childhood	childhood	NN
cord-017161-lcqrd4v0	445	6	:	:	:
cord-017161-lcqrd4v0	445	7	epidemiological	epidemiological	JJ
cord-017161-lcqrd4v0	445	8	and	and	CC
cord-017161-lcqrd4v0	445	9	clinical	clinical	JJ
cord-017161-lcqrd4v0	445	10	analysis	analysis	NN
cord-017161-lcqrd4v0	445	11	of	of	IN
cord-017161-lcqrd4v0	445	12	150	150	CD
cord-017161-lcqrd4v0	445	13	cases	case	NNS
cord-017161-lcqrd4v0	445	14	over	over	IN
cord-017161-lcqrd4v0	445	15	a	a	DT
cord-017161-lcqrd4v0	445	16	5-year	5-year	CD
cord-017161-lcqrd4v0	445	17	period	period	NN
cord-017161-lcqrd4v0	445	18	and	and	CC
cord-017161-lcqrd4v0	445	19	review	review	NN
cord-017161-lcqrd4v0	445	20	of	of	IN
cord-017161-lcqrd4v0	445	21	literature	literature	NN
cord-017161-lcqrd4v0	445	22	Group	Group	NNP
cord-017161-lcqrd4v0	445	23	A	A	NNP
cord-017161-lcqrd4v0	445	24	streptococcal	streptococcal	JJ
cord-017161-lcqrd4v0	445	25	antigen	antigen	NN
cord-017161-lcqrd4v0	445	26	in	in	IN
cord-017161-lcqrd4v0	445	27	the	the	DT
cord-017161-lcqrd4v0	445	28	glomeruli	glomerulus	NNS
cord-017161-lcqrd4v0	445	29	of	of	IN
cord-017161-lcqrd4v0	445	30	children	child	NNS
cord-017161-lcqrd4v0	445	31	with	with	IN
cord-017161-lcqrd4v0	445	32	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	445	33	-	-	HYPH
cord-017161-lcqrd4v0	445	34	Schönlein	Schönlein	NNP
cord-017161-lcqrd4v0	445	35	nephritis	nephritis	NN
cord-017161-lcqrd4v0	446	1	The	the	DT
cord-017161-lcqrd4v0	446	2	immunobiology	immunobiology	NN
cord-017161-lcqrd4v0	446	3	of	of	IN
cord-017161-lcqrd4v0	446	4	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	446	5	-	-	HYPH
cord-017161-lcqrd4v0	446	6	Schönlein	Schönlein	NNP
cord-017161-lcqrd4v0	446	7	purpura	purpura	NN
cord-017161-lcqrd4v0	446	8	IgA1	IgA1	NNP
cord-017161-lcqrd4v0	446	9	and	and	CC
cord-017161-lcqrd4v0	446	10	IgA2	IgA2	VBD
cord-017161-lcqrd4v0	446	11	in	in	IN
cord-017161-lcqrd4v0	446	12	circulating	circulate	VBG
cord-017161-lcqrd4v0	446	13	immune	immune	JJ
cord-017161-lcqrd4v0	446	14	complexes	complex	NNS
cord-017161-lcqrd4v0	446	15	and	and	CC
cord-017161-lcqrd4v0	446	16	in	in	IN
cord-017161-lcqrd4v0	446	17	renal	renal	JJ
cord-017161-lcqrd4v0	446	18	deposits	deposit	NNS
cord-017161-lcqrd4v0	446	19	of	of	IN
cord-017161-lcqrd4v0	446	20	Berger	Berger	NNP
cord-017161-lcqrd4v0	446	21	's	's	POS
cord-017161-lcqrd4v0	446	22	and	and	CC
cord-017161-lcqrd4v0	446	23	Schönlein	Schönlein	NNP
cord-017161-lcqrd4v0	446	24	-	-	HYPH
cord-017161-lcqrd4v0	446	25	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	446	26	glomerulonephritis	glomerulonephritis	NN
cord-017161-lcqrd4v0	446	27	Serum	serum	NN
cord-017161-lcqrd4v0	446	28	levels	level	NNS
cord-017161-lcqrd4v0	446	29	of	of	IN
cord-017161-lcqrd4v0	446	30	galactose	galactose	NN
cord-017161-lcqrd4v0	446	31	-	-	HYPH
cord-017161-lcqrd4v0	446	32	de	de	NNP
cord-017161-lcqrd4v0	446	33	fi	fi	NNP
cord-017161-lcqrd4v0	446	34	cient	cient	NNP
cord-017161-lcqrd4v0	446	35	IgA	IgA	NNP
cord-017161-lcqrd4v0	446	36	in	in	IN
cord-017161-lcqrd4v0	446	37	children	child	NNS
cord-017161-lcqrd4v0	446	38	with	with	IN
cord-017161-lcqrd4v0	446	39	IgA	IgA	NNP
cord-017161-lcqrd4v0	446	40	nephropathy	nephropathy	NNP
cord-017161-lcqrd4v0	446	41	and	and	CC
cord-017161-lcqrd4v0	446	42	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	446	43	-	-	HYPH
cord-017161-lcqrd4v0	446	44	Schönlein	Schönlein	NNP
cord-017161-lcqrd4v0	446	45	purpura	purpura	NN
cord-017161-lcqrd4v0	446	46	Activation	Activation	NNP
cord-017161-lcqrd4v0	446	47	of	of	IN
cord-017161-lcqrd4v0	446	48	the	the	DT
cord-017161-lcqrd4v0	446	49	lectin	lectin	NN
cord-017161-lcqrd4v0	446	50	complement	complement	NN
cord-017161-lcqrd4v0	446	51	pathway	pathway	NN
cord-017161-lcqrd4v0	446	52	in	in	IN
cord-017161-lcqrd4v0	446	53	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	446	54	-	-	HYPH
cord-017161-lcqrd4v0	446	55	Schönlein	Schönlein	NNP
cord-017161-lcqrd4v0	446	56	purpura	purpura	NN
cord-017161-lcqrd4v0	446	57	nephritis	nephritis	NN
cord-017161-lcqrd4v0	446	58	Complement	Complement	NNP
cord-017161-lcqrd4v0	446	59	activation	activation	NN
cord-017161-lcqrd4v0	446	60	in	in	IN
cord-017161-lcqrd4v0	446	61	IgA	IgA	NNP
cord-017161-lcqrd4v0	446	62	nephropathy	nephropathy	NN
cord-017161-lcqrd4v0	446	63	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	446	64	Schönlein	Schönlein	NNP
cord-017161-lcqrd4v0	446	65	purpura	purpura	NN
cord-017161-lcqrd4v0	446	66	with	with	IN
cord-017161-lcqrd4v0	446	67	hypocomplementemia	hypocomplementemia	NNP
cord-017161-lcqrd4v0	446	68	in	in	IN
cord-017161-lcqrd4v0	446	69	children	child	NNS
cord-017161-lcqrd4v0	446	70	HLA	HLA	NNP
cord-017161-lcqrd4v0	446	71	-	-	HYPH
cord-017161-lcqrd4v0	446	72	DRB1	DRB1	NNP
cord-017161-lcqrd4v0	446	73	alleles	allele	NNS
cord-017161-lcqrd4v0	446	74	and	and	CC
cord-017161-lcqrd4v0	446	75	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	446	76	-	-	HYPH
cord-017161-lcqrd4v0	446	77	Schönlein	Schönlein	NNP
cord-017161-lcqrd4v0	446	78	Purpura	Purpura	NNP
cord-017161-lcqrd4v0	446	79	:	:	:
cord-017161-lcqrd4v0	446	80	susceptibility	susceptibility	NN
cord-017161-lcqrd4v0	446	81	and	and	CC
cord-017161-lcqrd4v0	446	82	severity	severity	NN
cord-017161-lcqrd4v0	446	83	of	of	IN
cord-017161-lcqrd4v0	446	84	disease	disease	NN
cord-017161-lcqrd4v0	446	85	HLA	HLA	NNP
cord-017161-lcqrd4v0	446	86	-	-	HYPH
cord-017161-lcqrd4v0	446	87	DRB1	DRB1	NNP
cord-017161-lcqrd4v0	447	1	*	*	NFP
cord-017161-lcqrd4v0	447	2	01	01	CD
cord-017161-lcqrd4v0	447	3	association	association	NN
cord-017161-lcqrd4v0	447	4	with	with	IN
cord-017161-lcqrd4v0	447	5	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	447	6	-	-	HYPH
cord-017161-lcqrd4v0	447	7	Schönlein	Schönlein	NNP
cord-017161-lcqrd4v0	447	8	purpura	purpura	NN
cord-017161-lcqrd4v0	447	9	in	in	IN
cord-017161-lcqrd4v0	447	10	patients	patient	NNS
cord-017161-lcqrd4v0	447	11	from	from	IN
cord-017161-lcqrd4v0	447	12	northwest	northwest	NN
cord-017161-lcqrd4v0	447	13	Spain	Spain	NNP
cord-017161-lcqrd4v0	447	14	HLA	HLA	NNP
cord-017161-lcqrd4v0	447	15	class	class	NN
cord-017161-lcqrd4v0	447	16	1	1	CD
cord-017161-lcqrd4v0	447	17	associations	association	NNS
cord-017161-lcqrd4v0	447	18	in	in	IN
cord-017161-lcqrd4v0	447	19	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	447	20	Schonlein	Schonlein	NNP
cord-017161-lcqrd4v0	447	21	purpura	purpura	NN
cord-017161-lcqrd4v0	447	22	:	:	:
cord-017161-lcqrd4v0	447	23	increased	increase	VBN
cord-017161-lcqrd4v0	447	24	and	and	CC
cord-017161-lcqrd4v0	447	25	decreased	decrease	VBD
cord-017161-lcqrd4v0	447	26	frequencies	frequency	NNS
cord-017161-lcqrd4v0	447	27	HLA	HLA	NNP
cord-017161-lcqrd4v0	447	28	-	-	HYPH
cord-017161-lcqrd4v0	447	29	B35	B35	NNP
cord-017161-lcqrd4v0	447	30	association	association	NN
cord-017161-lcqrd4v0	447	31	with	with	IN
cord-017161-lcqrd4v0	447	32	nephritis	nephritis	NN
cord-017161-lcqrd4v0	447	33	in	in	IN
cord-017161-lcqrd4v0	448	1	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	448	2	-	-	HYPH
cord-017161-lcqrd4v0	448	3	Schönlein	Schönlein	NNP
cord-017161-lcqrd4v0	448	4	purpura	purpura	NN
cord-017161-lcqrd4v0	448	5	Interleukin	Interleukin	NNP
cord-017161-lcqrd4v0	448	6	8	8	CD
cord-017161-lcqrd4v0	448	7	gene	gene	NN
cord-017161-lcqrd4v0	448	8	polymorphism	polymorphism	NN
cord-017161-lcqrd4v0	448	9	is	be	VBZ
cord-017161-lcqrd4v0	448	10	associated	associate	VBN
cord-017161-lcqrd4v0	448	11	with	with	IN
cord-017161-lcqrd4v0	448	12	increased	increase	VBN
cord-017161-lcqrd4v0	448	13	risk	risk	NN
cord-017161-lcqrd4v0	448	14	of	of	IN
cord-017161-lcqrd4v0	448	15	nephritis	nephritis	NN
cord-017161-lcqrd4v0	448	16	in	in	IN
cord-017161-lcqrd4v0	448	17	cutaneous	cutaneous	JJ
cord-017161-lcqrd4v0	448	18	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	448	19	Macrophage	macrophage	NN
cord-017161-lcqrd4v0	448	20	migration	migration	NN
cord-017161-lcqrd4v0	448	21	inhibitory	inhibitory	JJ
cord-017161-lcqrd4v0	448	22	factor	factor	NN
cord-017161-lcqrd4v0	448	23	gene	gene	NN
cord-017161-lcqrd4v0	448	24	polymorphism	polymorphism	NN
cord-017161-lcqrd4v0	448	25	is	be	VBZ
cord-017161-lcqrd4v0	448	26	associated	associate	VBN
cord-017161-lcqrd4v0	448	27	with	with	IN
cord-017161-lcqrd4v0	448	28	sarcoidosis	sarcoidosis	NN
cord-017161-lcqrd4v0	448	29	in	in	IN
cord-017161-lcqrd4v0	448	30	biopsy	biopsy	NN
cord-017161-lcqrd4v0	448	31	proven	prove	VBN
cord-017161-lcqrd4v0	448	32	erythema	erythema	XX
cord-017161-lcqrd4v0	448	33	nodosum	nodosum	NNP
cord-017161-lcqrd4v0	448	34	Interleukin	Interleukin	NNP
cord-017161-lcqrd4v0	448	35	1beta	1beta	JJ
cord-017161-lcqrd4v0	448	36	gene	gene	NN
cord-017161-lcqrd4v0	448	37	polymorphism	polymorphism	NN
cord-017161-lcqrd4v0	448	38	association	association	NNP
cord-017161-lcqrd4v0	448	39	with	with	IN
cord-017161-lcqrd4v0	448	40	severe	severe	JJ
cord-017161-lcqrd4v0	448	41	renal	renal	JJ
cord-017161-lcqrd4v0	448	42	manifestations	manifestation	NNS
cord-017161-lcqrd4v0	448	43	and	and	CC
cord-017161-lcqrd4v0	448	44	renal	renal	JJ
cord-017161-lcqrd4v0	448	45	sequelae	sequela	NNS
cord-017161-lcqrd4v0	448	46	in	in	IN
cord-017161-lcqrd4v0	448	47	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	448	48	-	-	HYPH
cord-017161-lcqrd4v0	448	49	Schönlein	Schönlein	NNP
cord-017161-lcqrd4v0	448	50	purpura	purpura	NN
cord-017161-lcqrd4v0	448	51	Renin	renin	NN
cord-017161-lcqrd4v0	448	52	-	-	HYPH
cord-017161-lcqrd4v0	448	53	angiotensin	angiotensin	NN
cord-017161-lcqrd4v0	448	54	system	system	NN
cord-017161-lcqrd4v0	448	55	gene	gene	NN
cord-017161-lcqrd4v0	448	56	polymorphisms	polymorphism	NNS
cord-017161-lcqrd4v0	448	57	:	:	:
cord-017161-lcqrd4v0	448	58	association	association	NN
cord-017161-lcqrd4v0	448	59	with	with	IN
cord-017161-lcqrd4v0	448	60	susceptibility	susceptibility	NN
cord-017161-lcqrd4v0	448	61	to	to	IN
cord-017161-lcqrd4v0	448	62	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	448	63	-	-	HYPH
cord-017161-lcqrd4v0	448	64	Schönlein	Schönlein	NNP
cord-017161-lcqrd4v0	448	65	purpura	purpura	NN
cord-017161-lcqrd4v0	448	66	and	and	CC
cord-017161-lcqrd4v0	448	67	renal	renal	JJ
cord-017161-lcqrd4v0	448	68	involvement	involvement	NN
cord-017161-lcqrd4v0	448	69	Angiotensin	Angiotensin	NNP
cord-017161-lcqrd4v0	448	70	-	-	HYPH
cord-017161-lcqrd4v0	448	71	converting	convert	VBG
cord-017161-lcqrd4v0	448	72	enzyme	enzyme	NN
cord-017161-lcqrd4v0	448	73	gene	gene	NN
cord-017161-lcqrd4v0	448	74	insertion	insertion	NN
cord-017161-lcqrd4v0	448	75	/	/	SYM
cord-017161-lcqrd4v0	448	76	deletion	deletion	NN
cord-017161-lcqrd4v0	448	77	polymorphism	polymorphism	NN
cord-017161-lcqrd4v0	448	78	in	in	IN
cord-017161-lcqrd4v0	448	79	children	child	NNS
cord-017161-lcqrd4v0	448	80	with	with	IN
cord-017161-lcqrd4v0	448	81	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	448	82	-	-	HYPH
cord-017161-lcqrd4v0	448	83	Schonlein	Schonlein	NNP
cord-017161-lcqrd4v0	448	84	purpura	purpura	NN
cord-017161-lcqrd4v0	448	85	nephritis	nephritis	NN
cord-017161-lcqrd4v0	448	86	Association	Association	NNP
cord-017161-lcqrd4v0	448	87	between	between	IN
cord-017161-lcqrd4v0	448	88	functional	functional	JJ
cord-017161-lcqrd4v0	448	89	haplotypes	haplotype	NNS
cord-017161-lcqrd4v0	448	90	of	of	IN
cord-017161-lcqrd4v0	448	91	vascular	vascular	JJ
cord-017161-lcqrd4v0	448	92	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	448	93	growth	growth	NN
cord-017161-lcqrd4v0	448	94	factor	factor	NN
cord-017161-lcqrd4v0	448	95	and	and	CC
cord-017161-lcqrd4v0	448	96	renal	renal	JJ
cord-017161-lcqrd4v0	448	97	complications	complication	NNS
cord-017161-lcqrd4v0	448	98	in	in	IN
cord-017161-lcqrd4v0	448	99	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	448	100	-	-	HYPH
cord-017161-lcqrd4v0	448	101	Schönlein	Schönlein	NNP
cord-017161-lcqrd4v0	448	102	purpura	purpura	NN
cord-017161-lcqrd4v0	448	103	Prevalence	Prevalence	NNP
cord-017161-lcqrd4v0	448	104	and	and	CC
cord-017161-lcqrd4v0	448	105	signi	signi	NNP
cord-017161-lcqrd4v0	448	106	fi	fi	NN
cord-017161-lcqrd4v0	448	107	cance	cance	NN
cord-017161-lcqrd4v0	448	108	of	of	IN
cord-017161-lcqrd4v0	448	109	mutations	mutation	NNS
cord-017161-lcqrd4v0	448	110	in	in	IN
cord-017161-lcqrd4v0	448	111	the	the	DT
cord-017161-lcqrd4v0	448	112	familial	familial	JJ
cord-017161-lcqrd4v0	448	113	Mediterranean	Mediterranean	NNP
cord-017161-lcqrd4v0	448	114	fever	fever	NN
cord-017161-lcqrd4v0	448	115	gene	gene	NN
cord-017161-lcqrd4v0	448	116	in	in	IN
cord-017161-lcqrd4v0	448	117	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	448	118	-	-	HYPH
cord-017161-lcqrd4v0	448	119	Schönlein	Schönlein	NNP
cord-017161-lcqrd4v0	448	120	purpura	purpura	NN
cord-017161-lcqrd4v0	448	121	Study	Study	NNP
cord-017161-lcqrd4v0	448	122	group	group	NN
cord-017161-lcqrd4v0	448	123	familial	familial	JJ
cord-017161-lcqrd4v0	448	124	Mediterranean	mediterranean	JJ
cord-017161-lcqrd4v0	448	125	fever	fever	NN
cord-017161-lcqrd4v0	448	126	(	(	-LRB-
cord-017161-lcqrd4v0	448	127	FMF	FMF	NNP
cord-017161-lcqrd4v0	448	128	)	)	-RRB-
cord-017161-lcqrd4v0	448	129	in	in	IN
cord-017161-lcqrd4v0	448	130	Turkey	Turkey	NNP
cord-017161-lcqrd4v0	448	131	:	:	:
cord-017161-lcqrd4v0	448	132	results	result	NNS
cord-017161-lcqrd4v0	448	133	of	of	IN
cord-017161-lcqrd4v0	448	134	a	a	DT
cord-017161-lcqrd4v0	448	135	nationwide	nationwide	JJ
cord-017161-lcqrd4v0	448	136	multicenter	multicenter	JJ
cord-017161-lcqrd4v0	448	137	study	study	NN
cord-017161-lcqrd4v0	448	138	Increased	increase	VBN
cord-017161-lcqrd4v0	448	139	frequency	frequency	NN
cord-017161-lcqrd4v0	448	140	of	of	IN
cord-017161-lcqrd4v0	448	141	C4B	c4b	NN
cord-017161-lcqrd4v0	448	142	*	*	NFP
cord-017161-lcqrd4v0	448	143	Q0	q0	NN
cord-017161-lcqrd4v0	448	144	alleles	allele	NNS
cord-017161-lcqrd4v0	448	145	in	in	IN
cord-017161-lcqrd4v0	448	146	patients	patient	NNS
cord-017161-lcqrd4v0	448	147	with	with	IN
cord-017161-lcqrd4v0	448	148	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	448	149	-	-	HYPH
cord-017161-lcqrd4v0	448	150	Schönlein	Schönlein	NNP
cord-017161-lcqrd4v0	448	151	purpura	purpura	NN
cord-017161-lcqrd4v0	448	152	Role	role	NN
cord-017161-lcqrd4v0	448	153	of	of	IN
cord-017161-lcqrd4v0	448	154	PAX2	PAX2	NNP
cord-017161-lcqrd4v0	448	155	gene	gene	NN
cord-017161-lcqrd4v0	448	156	polymorphisms	polymorphism	NNS
cord-017161-lcqrd4v0	448	157	in	in	IN
cord-017161-lcqrd4v0	448	158	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	448	159	-	-	HYPH
cord-017161-lcqrd4v0	448	160	Schonlein	Schonlein	NNP
cord-017161-lcqrd4v0	448	161	purpura	purpura	NN
cord-017161-lcqrd4v0	448	162	nephritis	nephritis	NN
cord-017161-lcqrd4v0	449	1	Inducible	inducible	JJ
cord-017161-lcqrd4v0	449	2	nitric	nitric	JJ
cord-017161-lcqrd4v0	449	3	oxide	oxide	NN
cord-017161-lcqrd4v0	449	4	synthase	synthase	NN
cord-017161-lcqrd4v0	449	5	polymorphism	polymorphism	NN
cord-017161-lcqrd4v0	449	6	is	be	VBZ
cord-017161-lcqrd4v0	449	7	associated	associate	VBN
cord-017161-lcqrd4v0	449	8	with	with	IN
cord-017161-lcqrd4v0	449	9	susceptibility	susceptibility	NN
cord-017161-lcqrd4v0	449	10	to	to	IN
cord-017161-lcqrd4v0	449	11	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	449	12	-	-	HYPH
cord-017161-lcqrd4v0	449	13	Schönlein	Schönlein	NNP
cord-017161-lcqrd4v0	449	14	purpura	purpura	NN
cord-017161-lcqrd4v0	449	15	in	in	IN
cord-017161-lcqrd4v0	449	16	northwestern	northwestern	JJ
cord-017161-lcqrd4v0	449	17	Spain	Spain	NNP
cord-017161-lcqrd4v0	449	18	Genetics	Genetics	NNP
cord-017161-lcqrd4v0	449	19	of	of	IN
cord-017161-lcqrd4v0	449	20	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	449	21	Immunogenetics	immunogenetic	NNS
cord-017161-lcqrd4v0	449	22	of	of	IN
cord-017161-lcqrd4v0	449	23	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	449	24	-	-	HYPH
cord-017161-lcqrd4v0	449	25	Schönlein	Schönlein	NNP
cord-017161-lcqrd4v0	449	26	disease	disease	NN
cord-017161-lcqrd4v0	449	27	Small	small	JJ
cord-017161-lcqrd4v0	449	28	vessel	vessel	NN
cord-017161-lcqrd4v0	449	29	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	450	1	A	a	DT
cord-017161-lcqrd4v0	450	2	randomized	randomized	JJ
cord-017161-lcqrd4v0	450	3	,	,	,
cord-017161-lcqrd4v0	450	4	placebo	placebo	NN
cord-017161-lcqrd4v0	450	5	-	-	HYPH
cord-017161-lcqrd4v0	450	6	controlled	control	VBN
cord-017161-lcqrd4v0	450	7	trial	trial	NN
cord-017161-lcqrd4v0	450	8	of	of	IN
cord-017161-lcqrd4v0	450	9	prednisone	prednisone	NNP
cord-017161-lcqrd4v0	450	10	in	in	IN
cord-017161-lcqrd4v0	450	11	early	early	JJ
cord-017161-lcqrd4v0	450	12	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	450	13	Schonlein	Schonlein	NNP
cord-017161-lcqrd4v0	450	14	purpura	purpura	NN
cord-017161-lcqrd4v0	450	15	Early	early	JJ
cord-017161-lcqrd4v0	450	16	prednisone	prednisone	JJ
cord-017161-lcqrd4v0	450	17	therapy	therapy	NN
cord-017161-lcqrd4v0	450	18	in	in	IN
cord-017161-lcqrd4v0	450	19	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	450	20	-	-	HYPH
cord-017161-lcqrd4v0	450	21	Schonlein	Schonlein	NNP
cord-017161-lcqrd4v0	450	22	purpura	purpura	NN
cord-017161-lcqrd4v0	450	23	:	:	:
cord-017161-lcqrd4v0	450	24	a	a	DT
cord-017161-lcqrd4v0	450	25	randomized	randomized	JJ
cord-017161-lcqrd4v0	450	26	,	,	,
cord-017161-lcqrd4v0	450	27	double	double	JJ
cord-017161-lcqrd4v0	450	28	-	-	HYPH
cord-017161-lcqrd4v0	450	29	blind	blind	JJ
cord-017161-lcqrd4v0	450	30	,	,	,
cord-017161-lcqrd4v0	450	31	placebo	placebo	NN
cord-017161-lcqrd4v0	450	32	-	-	HYPH
cord-017161-lcqrd4v0	450	33	controlled	control	VBN
cord-017161-lcqrd4v0	450	34	trial	trial	NN
cord-017161-lcqrd4v0	450	35	Prevention	prevention	NN
cord-017161-lcqrd4v0	450	36	and	and	CC
cord-017161-lcqrd4v0	450	37	treatment	treatment	NN
cord-017161-lcqrd4v0	450	38	of	of	IN
cord-017161-lcqrd4v0	450	39	renal	renal	JJ
cord-017161-lcqrd4v0	450	40	disease	disease	NN
cord-017161-lcqrd4v0	450	41	in	in	IN
cord-017161-lcqrd4v0	450	42	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	450	43	-	-	HYPH
cord-017161-lcqrd4v0	450	44	Schonlein	Schonlein	NNP
cord-017161-lcqrd4v0	450	45	purpura	purpura	NN
cord-017161-lcqrd4v0	450	46	:	:	:
cord-017161-lcqrd4v0	450	47	a	a	DT
cord-017161-lcqrd4v0	450	48	systematic	systematic	JJ
cord-017161-lcqrd4v0	450	49	review	review	NN
cord-017161-lcqrd4v0	450	50	Randomised	randomised	JJ
cord-017161-lcqrd4v0	450	51	placebo	placebo	NN
cord-017161-lcqrd4v0	450	52	controlled	control	VBN
cord-017161-lcqrd4v0	450	53	trial	trial	NN
cord-017161-lcqrd4v0	450	54	to	to	TO
cord-017161-lcqrd4v0	450	55	assess	assess	VB
cord-017161-lcqrd4v0	450	56	the	the	DT
cord-017161-lcqrd4v0	450	57	role	role	NN
cord-017161-lcqrd4v0	450	58	of	of	IN
cord-017161-lcqrd4v0	450	59	early	early	JJ
cord-017161-lcqrd4v0	450	60	prednisolone	prednisolone	NN
cord-017161-lcqrd4v0	450	61	on	on	IN
cord-017161-lcqrd4v0	450	62	the	the	DT
cord-017161-lcqrd4v0	450	63	development	development	NN
cord-017161-lcqrd4v0	450	64	and	and	CC
cord-017161-lcqrd4v0	450	65	progression	progression	NN
cord-017161-lcqrd4v0	450	66	of	of	IN
cord-017161-lcqrd4v0	450	67	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	450	68	-	-	HYPH
cord-017161-lcqrd4v0	450	69	Schonlein	Schonlein	NNP
cord-017161-lcqrd4v0	450	70	purpura	purpura	NN
cord-017161-lcqrd4v0	450	71	nephritis	nephritis	NN
cord-017161-lcqrd4v0	450	72	Treatment	treatment	NN
cord-017161-lcqrd4v0	450	73	of	of	IN
cord-017161-lcqrd4v0	450	74	complicated	complicated	JJ
cord-017161-lcqrd4v0	450	75	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	450	76	-	-	HYPH
cord-017161-lcqrd4v0	450	77	Schonlein	Schonlein	NNP
cord-017161-lcqrd4v0	450	78	Purpura	Purpura	NNP
cord-017161-lcqrd4v0	450	79	with	with	IN
cord-017161-lcqrd4v0	450	80	mycophenolate	mycophenolate	NNP
cord-017161-lcqrd4v0	450	81	mofetil	mofetil	NNP
cord-017161-lcqrd4v0	450	82	:	:	:
cord-017161-lcqrd4v0	451	1	a	a	DT
cord-017161-lcqrd4v0	451	2	retrospective	retrospective	JJ
cord-017161-lcqrd4v0	451	3	case	case	NN
cord-017161-lcqrd4v0	451	4	series	series	NN
cord-017161-lcqrd4v0	451	5	report	report	NN
cord-017161-lcqrd4v0	451	6	Therapy	Therapy	NNP
cord-017161-lcqrd4v0	451	7	for	for	IN
cord-017161-lcqrd4v0	451	8	children	child	NNS
cord-017161-lcqrd4v0	451	9	with	with	IN
cord-017161-lcqrd4v0	451	10	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	451	11	-	-	HYPH
cord-017161-lcqrd4v0	451	12	Schonlein	Schonlein	NNP
cord-017161-lcqrd4v0	451	13	purpura	purpura	NN
cord-017161-lcqrd4v0	451	14	nephritis	nephritis	NN
cord-017161-lcqrd4v0	451	15	:	:	:
cord-017161-lcqrd4v0	451	16	a	a	DT
cord-017161-lcqrd4v0	451	17	systematic	systematic	JJ
cord-017161-lcqrd4v0	451	18	review	review	NN
cord-017161-lcqrd4v0	451	19	Cyclosporin	Cyclosporin	NNP
cord-017161-lcqrd4v0	451	20	A	a	NN
cord-017161-lcqrd4v0	451	21	for	for	IN
cord-017161-lcqrd4v0	451	22	the	the	DT
cord-017161-lcqrd4v0	451	23	treatment	treatment	NN
cord-017161-lcqrd4v0	451	24	of	of	IN
cord-017161-lcqrd4v0	451	25	severe	severe	JJ
cord-017161-lcqrd4v0	451	26	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	451	27	-	-	HYPH
cord-017161-lcqrd4v0	451	28	Schonlein	Schonlein	NNP
cord-017161-lcqrd4v0	451	29	glomerulonephritis	glomerulonephritis	NN
cord-017161-lcqrd4v0	451	30	Severe	severe	JJ
cord-017161-lcqrd4v0	451	31	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	451	32	-	-	HYPH
cord-017161-lcqrd4v0	451	33	Schonlein	Schonlein	NNP
cord-017161-lcqrd4v0	451	34	nephritis	nephritis	NN
cord-017161-lcqrd4v0	451	35	:	:	:
cord-017161-lcqrd4v0	452	1	resolution	resolution	NN
cord-017161-lcqrd4v0	452	2	with	with	IN
cord-017161-lcqrd4v0	452	3	azathioprine	azathioprine	NN
cord-017161-lcqrd4v0	452	4	and	and	CC
cord-017161-lcqrd4v0	452	5	steroids	steroid	NNS
cord-017161-lcqrd4v0	452	6	Treating	treat	VBG
cord-017161-lcqrd4v0	452	7	severe	severe	JJ
cord-017161-lcqrd4v0	452	8	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	452	9	-	-	HYPH
cord-017161-lcqrd4v0	452	10	Schonlein	Schonlein	NNP
cord-017161-lcqrd4v0	452	11	and	and	CC
cord-017161-lcqrd4v0	452	12	IgA	IgA	NNP
cord-017161-lcqrd4v0	452	13	nephritis	nephritis	NN
cord-017161-lcqrd4v0	452	14	with	with	IN
cord-017161-lcqrd4v0	452	15	plasmapheresis	plasmapheresis	NN
cord-017161-lcqrd4v0	452	16	alone	alone	RB
cord-017161-lcqrd4v0	453	1	Risk	risk	NN
cord-017161-lcqrd4v0	453	2	of	of	IN
cord-017161-lcqrd4v0	453	3	long	long	JJ
cord-017161-lcqrd4v0	453	4	term	term	NN
cord-017161-lcqrd4v0	453	5	renal	renal	JJ
cord-017161-lcqrd4v0	453	6	impairment	impairment	NN
cord-017161-lcqrd4v0	453	7	and	and	CC
cord-017161-lcqrd4v0	453	8	duration	duration	NN
cord-017161-lcqrd4v0	453	9	of	of	IN
cord-017161-lcqrd4v0	453	10	follow	follow	NN
cord-017161-lcqrd4v0	453	11	up	up	RP
cord-017161-lcqrd4v0	453	12	recommended	recommend	VBN
cord-017161-lcqrd4v0	453	13	for	for	IN
cord-017161-lcqrd4v0	453	14	Henoch	Henoch	NNP
cord-017161-lcqrd4v0	453	15	-	-	HYPH
cord-017161-lcqrd4v0	453	16	Schönlein	Schönlein	NNP
cord-017161-lcqrd4v0	453	17	purpura	purpura	NN
cord-017161-lcqrd4v0	453	18	with	with	IN
cord-017161-lcqrd4v0	453	19	normal	normal	JJ
cord-017161-lcqrd4v0	453	20	or	or	CC
cord-017161-lcqrd4v0	453	21	minimal	minimal	JJ
cord-017161-lcqrd4v0	453	22	urinary	urinary	JJ
cord-017161-lcqrd4v0	453	23	fi	fi	NN
cord-017161-lcqrd4v0	453	24	ndings	nding	NNS
cord-017161-lcqrd4v0	453	25	:	:	:
cord-017161-lcqrd4v0	453	26	a	a	DT
cord-017161-lcqrd4v0	453	27	systematic	systematic	JJ
cord-017161-lcqrd4v0	453	28	review	review	NN
cord-017161-lcqrd4v0	453	29	Acute	Acute	NNP
cord-017161-lcqrd4v0	453	30	febrile	febrile	JJ
cord-017161-lcqrd4v0	453	31	mucocutaneous	mucocutaneous	JJ
cord-017161-lcqrd4v0	453	32	syndrome	syndrome	NN
cord-017161-lcqrd4v0	453	33	with	with	IN
cord-017161-lcqrd4v0	453	34	lymphoid	lymphoid	JJ
cord-017161-lcqrd4v0	453	35	involvement	involvement	NN
cord-017161-lcqrd4v0	453	36	with	with	IN
cord-017161-lcqrd4v0	453	37	speci	speci	NNP
cord-017161-lcqrd4v0	453	38	fi	fi	NNP
cord-017161-lcqrd4v0	453	39	c	c	NNP
cord-017161-lcqrd4v0	453	40	desquamation	desquamation	NN
cord-017161-lcqrd4v0	453	41	of	of	IN
cord-017161-lcqrd4v0	453	42	the	the	DT
cord-017161-lcqrd4v0	453	43	fi	fi	NNP
cord-017161-lcqrd4v0	453	44	ngers	nger	NNS
cord-017161-lcqrd4v0	453	45	and	and	CC
cord-017161-lcqrd4v0	453	46	toes	toe	NNS
cord-017161-lcqrd4v0	453	47	in	in	IN
cord-017161-lcqrd4v0	453	48	children	child	NNS
cord-017161-lcqrd4v0	453	49	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	453	50	disease	disease	NN
cord-017161-lcqrd4v0	453	51	:	:	:
cord-017161-lcqrd4v0	453	52	an	an	DT
cord-017161-lcqrd4v0	453	53	evidence	evidence	NN
cord-017161-lcqrd4v0	453	54	based	base	VBN
cord-017161-lcqrd4v0	453	55	approach	approach	NN
cord-017161-lcqrd4v0	453	56	to	to	IN
cord-017161-lcqrd4v0	453	57	diagnosis	diagnosis	NN
cord-017161-lcqrd4v0	453	58	,	,	,
cord-017161-lcqrd4v0	453	59	treatment	treatment	NN
cord-017161-lcqrd4v0	453	60	,	,	,
cord-017161-lcqrd4v0	453	61	and	and	CC
cord-017161-lcqrd4v0	453	62	proposals	proposal	NNS
cord-017161-lcqrd4v0	453	63	for	for	IN
cord-017161-lcqrd4v0	453	64	future	future	JJ
cord-017161-lcqrd4v0	453	65	research	research	NN
cord-017161-lcqrd4v0	453	66	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	453	67	syndrome	syndrome	NN
cord-017161-lcqrd4v0	453	68	Diagnosis	diagnosis	NN
cord-017161-lcqrd4v0	453	69	,	,	,
cord-017161-lcqrd4v0	453	70	treatment	treatment	NN
cord-017161-lcqrd4v0	453	71	,	,	,
cord-017161-lcqrd4v0	453	72	and	and	CC
cord-017161-lcqrd4v0	453	73	long	long	JJ
cord-017161-lcqrd4v0	453	74	-	-	HYPH
cord-017161-lcqrd4v0	453	75	term	term	NN
cord-017161-lcqrd4v0	453	76	management	management	NN
cord-017161-lcqrd4v0	453	77	of	of	IN
cord-017161-lcqrd4v0	453	78	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	453	79	disease	disease	NN
cord-017161-lcqrd4v0	453	80	:	:	:
cord-017161-lcqrd4v0	453	81	a	a	DT
cord-017161-lcqrd4v0	453	82	statement	statement	NN
cord-017161-lcqrd4v0	453	83	for	for	IN
cord-017161-lcqrd4v0	453	84	health	health	NN
cord-017161-lcqrd4v0	453	85	professionals	professional	NNS
cord-017161-lcqrd4v0	453	86	from	from	IN
cord-017161-lcqrd4v0	453	87	the	the	DT
cord-017161-lcqrd4v0	453	88	committee	committee	NN
cord-017161-lcqrd4v0	453	89	on	on	IN
cord-017161-lcqrd4v0	453	90	rheumatic	rheumatic	JJ
cord-017161-lcqrd4v0	453	91	fever	fever	NN
cord-017161-lcqrd4v0	453	92	,	,	,
cord-017161-lcqrd4v0	453	93	endocarditis	endocarditis	NN
cord-017161-lcqrd4v0	453	94	,	,	,
cord-017161-lcqrd4v0	453	95	and	and	CC
cord-017161-lcqrd4v0	453	96	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	453	97	disease	disease	NN
cord-017161-lcqrd4v0	453	98	,	,	,
cord-017161-lcqrd4v0	453	99	council	council	NN
cord-017161-lcqrd4v0	453	100	on	on	IN
cord-017161-lcqrd4v0	453	101	cardiovascular	cardiovascular	JJ
cord-017161-lcqrd4v0	453	102	disease	disease	NN
cord-017161-lcqrd4v0	453	103	in	in	IN
cord-017161-lcqrd4v0	453	104	the	the	DT
cord-017161-lcqrd4v0	453	105	young	young	JJ
cord-017161-lcqrd4v0	453	106	Recognition	Recognition	NNP
cord-017161-lcqrd4v0	453	107	and	and	CC
cord-017161-lcqrd4v0	453	108	management	management	NN
cord-017161-lcqrd4v0	453	109	of	of	IN
cord-017161-lcqrd4v0	453	110	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	453	111	disease	disease	NN
cord-017161-lcqrd4v0	453	112	Incidence	incidence	NN
cord-017161-lcqrd4v0	453	113	of	of	IN
cord-017161-lcqrd4v0	453	114	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	453	115	disease	disease	NN
cord-017161-lcqrd4v0	453	116	in	in	IN
cord-017161-lcqrd4v0	453	117	Japan	Japan	NNP
cord-017161-lcqrd4v0	453	118	:	:	:
cord-017161-lcqrd4v0	453	119	the	the	DT
cord-017161-lcqrd4v0	453	120	nationwide	nationwide	JJ
cord-017161-lcqrd4v0	453	121	surveys	survey	NNS
cord-017161-lcqrd4v0	453	122	of	of	IN
cord-017161-lcqrd4v0	453	123	1999	1999	CD
cord-017161-lcqrd4v0	453	124	-	-	SYM
cord-017161-lcqrd4v0	453	125	2002	2002	CD
cord-017161-lcqrd4v0	453	126	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	453	127	syndrome	syndrome	NN
cord-017161-lcqrd4v0	453	128	hospitalizations	hospitalization	NNS
cord-017161-lcqrd4v0	453	129	in	in	IN
cord-017161-lcqrd4v0	453	130	the	the	DT
cord-017161-lcqrd4v0	453	131	United	United	NNP
cord-017161-lcqrd4v0	453	132	States	States	NNP
cord-017161-lcqrd4v0	453	133	Rising	rise	VBG
cord-017161-lcqrd4v0	453	134	incidence	incidence	NN
cord-017161-lcqrd4v0	453	135	of	of	IN
cord-017161-lcqrd4v0	453	136	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	453	137	disease	disease	NN
cord-017161-lcqrd4v0	453	138	in	in	IN
cord-017161-lcqrd4v0	453	139	England	England	NNP
cord-017161-lcqrd4v0	453	140	:	:	:
cord-017161-lcqrd4v0	453	141	analysis	analysis	NN
cord-017161-lcqrd4v0	453	142	of	of	IN
cord-017161-lcqrd4v0	453	143	hospital	hospital	NN
cord-017161-lcqrd4v0	453	144	admission	admission	NN
cord-017161-lcqrd4v0	453	145	data	datum	NNS
cord-017161-lcqrd4v0	453	146	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	453	147	disease	disease	NN
cord-017161-lcqrd4v0	453	148	:	:	:
cord-017161-lcqrd4v0	454	1	update	update	VB
cord-017161-lcqrd4v0	454	2	on	on	IN
cord-017161-lcqrd4v0	454	3	pathogenesis	pathogenesis	NN
cord-017161-lcqrd4v0	454	4	Medium	medium	NN
cord-017161-lcqrd4v0	454	5	-	-	HYPH
cord-017161-lcqrd4v0	454	6	size	size	NN
cord-017161-lcqrd4v0	454	7	-	-	HYPH
cord-017161-lcqrd4v0	454	8	vessel	vessel	NN
cord-017161-lcqrd4v0	454	9	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	454	10	Lack	Lack	NNP
cord-017161-lcqrd4v0	454	11	of	of	IN
cord-017161-lcqrd4v0	454	12	association	association	NN
cord-017161-lcqrd4v0	454	13	between	between	IN
cord-017161-lcqrd4v0	454	14	infection	infection	NN
cord-017161-lcqrd4v0	454	15	with	with	IN
cord-017161-lcqrd4v0	454	16	a	a	DT
cord-017161-lcqrd4v0	454	17	novel	novel	JJ
cord-017161-lcqrd4v0	454	18	human	human	JJ
cord-017161-lcqrd4v0	454	19	coronavirus	coronavirus	NN
cord-017161-lcqrd4v0	454	20	(	(	-LRB-
cord-017161-lcqrd4v0	454	21	HCoV	HCoV	NNP
cord-017161-lcqrd4v0	454	22	)	)	-RRB-
cord-017161-lcqrd4v0	454	23	,	,	,
cord-017161-lcqrd4v0	454	24	HCoV	HCoV	NNP
cord-017161-lcqrd4v0	454	25	-	-	HYPH
cord-017161-lcqrd4v0	454	26	NH	NH	NNP
cord-017161-lcqrd4v0	454	27	,	,	,
cord-017161-lcqrd4v0	454	28	and	and	CC
cord-017161-lcqrd4v0	454	29	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	454	30	disease	disease	NN
cord-017161-lcqrd4v0	454	31	in	in	IN
cord-017161-lcqrd4v0	454	32	Taiwan	Taiwan	NNP
cord-017161-lcqrd4v0	454	33	V	V	NNP
cord-017161-lcqrd4v0	454	34	restricted	restrict	VBD
cord-017161-lcqrd4v0	454	35	T	t	NN
cord-017161-lcqrd4v0	454	36	cell	cell	NN
cord-017161-lcqrd4v0	454	37	adherence	adherence	NN
cord-017161-lcqrd4v0	454	38	to	to	IN
cord-017161-lcqrd4v0	454	39	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	454	40	cells	cell	NNS
cord-017161-lcqrd4v0	454	41	:	:	:
cord-017161-lcqrd4v0	455	1	a	a	DT
cord-017161-lcqrd4v0	455	2	mechanism	mechanism	NN
cord-017161-lcqrd4v0	455	3	for	for	IN
cord-017161-lcqrd4v0	455	4	superantigen	superantigen	NN
cord-017161-lcqrd4v0	455	5	dependent	dependent	JJ
cord-017161-lcqrd4v0	455	6	vascular	vascular	JJ
cord-017161-lcqrd4v0	455	7	injury	injury	NN
cord-017161-lcqrd4v0	455	8	Superantigens	Superantigens	NNP
cord-017161-lcqrd4v0	455	9	:	:	:
cord-017161-lcqrd4v0	455	10	mechanism	mechanism	NN
cord-017161-lcqrd4v0	455	11	of	of	IN
cord-017161-lcqrd4v0	455	12	T	t	NN
cord-017161-lcqrd4v0	455	13	-	-	HYPH
cord-017161-lcqrd4v0	455	14	cell	cell	NN
cord-017161-lcqrd4v0	455	15	stimulation	stimulation	NN
cord-017161-lcqrd4v0	455	16	and	and	CC
cord-017161-lcqrd4v0	455	17	role	role	NN
cord-017161-lcqrd4v0	455	18	in	in	IN
cord-017161-lcqrd4v0	455	19	immune	immune	JJ
cord-017161-lcqrd4v0	455	20	responses	response	NNS
cord-017161-lcqrd4v0	455	21	Superantigenic	Superantigenic	NNP
cord-017161-lcqrd4v0	455	22	activity	activity	NN
cord-017161-lcqrd4v0	455	23	is	be	VBZ
cord-017161-lcqrd4v0	455	24	responsible	responsible	JJ
cord-017161-lcqrd4v0	455	25	for	for	IN
cord-017161-lcqrd4v0	455	26	induction	induction	NN
cord-017161-lcqrd4v0	455	27	of	of	IN
cord-017161-lcqrd4v0	455	28	coronary	coronary	JJ
cord-017161-lcqrd4v0	455	29	arteritis	arteritis	NN
cord-017161-lcqrd4v0	455	30	in	in	IN
cord-017161-lcqrd4v0	455	31	mice	mice	NN
cord-017161-lcqrd4v0	455	32	:	:	:
cord-017161-lcqrd4v0	455	33	an	an	DT
cord-017161-lcqrd4v0	455	34	animal	animal	NN
cord-017161-lcqrd4v0	455	35	model	model	NN
cord-017161-lcqrd4v0	455	36	of	of	IN
cord-017161-lcqrd4v0	455	37	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	455	38	disease	disease	NN
cord-017161-lcqrd4v0	455	39	Selective	selective	JJ
cord-017161-lcqrd4v0	455	40	expansion	expansion	NN
cord-017161-lcqrd4v0	455	41	of	of	IN
cord-017161-lcqrd4v0	455	42	T	T	NNP
cord-017161-lcqrd4v0	455	43	cells	cell	NNS
cord-017161-lcqrd4v0	455	44	expressing	express	VBG
cord-017161-lcqrd4v0	455	45	T	t	NN
cord-017161-lcqrd4v0	455	46	-	-	HYPH
cord-017161-lcqrd4v0	455	47	cell	cell	NN
cord-017161-lcqrd4v0	455	48	receptor	receptor	NN
cord-017161-lcqrd4v0	455	49	variable	variable	NN
cord-017161-lcqrd4v0	455	50	regions	region	NNS
cord-017161-lcqrd4v0	455	51	V	v	NN
cord-017161-lcqrd4v0	455	52	beta	beta	NN
cord-017161-lcqrd4v0	455	53	2	2	CD
cord-017161-lcqrd4v0	455	54	and	and	CC
cord-017161-lcqrd4v0	455	55	V	v	NN
cord-017161-lcqrd4v0	455	56	beta	beta	NN
cord-017161-lcqrd4v0	455	57	8	8	CD
cord-017161-lcqrd4v0	455	58	in	in	IN
cord-017161-lcqrd4v0	455	59	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	455	60	disease	disease	NN
cord-017161-lcqrd4v0	455	61	Prevalence	prevalence	NN
cord-017161-lcqrd4v0	455	62	of	of	IN
cord-017161-lcqrd4v0	455	63	superantigen	superantigen	NN
cord-017161-lcqrd4v0	455	64	-	-	HYPH
cord-017161-lcqrd4v0	455	65	secreting	secrete	VBG
cord-017161-lcqrd4v0	455	66	bacteria	bacteria	NNS
cord-017161-lcqrd4v0	455	67	in	in	IN
cord-017161-lcqrd4v0	455	68	patients	patient	NNS
cord-017161-lcqrd4v0	455	69	with	with	IN
cord-017161-lcqrd4v0	455	70	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	455	71	disease	disease	NN
cord-017161-lcqrd4v0	455	72	Development	Development	NNP
cord-017161-lcqrd4v0	455	73	of	of	IN
cord-017161-lcqrd4v0	455	74	serum	serum	NNP
cord-017161-lcqrd4v0	455	75	IgM	IgM	NNP
cord-017161-lcqrd4v0	455	76	antibodies	antibody	NNS
cord-017161-lcqrd4v0	455	77	against	against	IN
cord-017161-lcqrd4v0	455	78	superantigens	superantigen	NNS
cord-017161-lcqrd4v0	455	79	of	of	IN
cord-017161-lcqrd4v0	455	80	Staphylococcus	Staphylococcus	NNP
cord-017161-lcqrd4v0	455	81	aureus	aureus	NN
cord-017161-lcqrd4v0	455	82	and	and	CC
cord-017161-lcqrd4v0	455	83	Streptococcus	streptococcus	NN
cord-017161-lcqrd4v0	455	84	pyogenes	pyogene	NNS
cord-017161-lcqrd4v0	455	85	in	in	IN
cord-017161-lcqrd4v0	455	86	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	455	87	disease	disease	NN
cord-017161-lcqrd4v0	455	88	Detection	detection	NN
cord-017161-lcqrd4v0	455	89	of	of	IN
cord-017161-lcqrd4v0	455	90	antigen	antigen	NN
cord-017161-lcqrd4v0	455	91	in	in	IN
cord-017161-lcqrd4v0	455	92	bronchial	bronchial	JJ
cord-017161-lcqrd4v0	455	93	epithelium	epithelium	NN
cord-017161-lcqrd4v0	455	94	and	and	CC
cord-017161-lcqrd4v0	455	95	macrophages	macrophage	NNS
cord-017161-lcqrd4v0	455	96	in	in	IN
cord-017161-lcqrd4v0	455	97	acute	acute	JJ
cord-017161-lcqrd4v0	455	98	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	455	99	disease	disease	NN
cord-017161-lcqrd4v0	455	100	by	by	IN
cord-017161-lcqrd4v0	455	101	use	use	NN
cord-017161-lcqrd4v0	455	102	of	of	IN
cord-017161-lcqrd4v0	455	103	synthetic	synthetic	JJ
cord-017161-lcqrd4v0	455	104	antibody	antibody	NN
cord-017161-lcqrd4v0	455	105	Coronary	coronary	JJ
cord-017161-lcqrd4v0	455	106	arthritis	arthritis	NN
cord-017161-lcqrd4v0	455	107	in	in	IN
cord-017161-lcqrd4v0	455	108	mice	mouse	NNS
cord-017161-lcqrd4v0	455	109	following	follow	VBG
cord-017161-lcqrd4v0	455	110	the	the	DT
cord-017161-lcqrd4v0	455	111	systemic	systemic	JJ
cord-017161-lcqrd4v0	455	112	injection	injection	NN
cord-017161-lcqrd4v0	455	113	of	of	IN
cord-017161-lcqrd4v0	455	114	group	group	NN
cord-017161-lcqrd4v0	455	115	b	b	NNP
cord-017161-lcqrd4v0	455	116	Lactobacillus	lactobacillus	NN
cord-017161-lcqrd4v0	455	117	casei	casei	NN
cord-017161-lcqrd4v0	455	118	cell	cell	NN
cord-017161-lcqrd4v0	455	119	walls	wall	NNS
cord-017161-lcqrd4v0	455	120	in	in	IN
cord-017161-lcqrd4v0	455	121	aqueous	aqueous	JJ
cord-017161-lcqrd4v0	455	122	suspension	suspension	NN
cord-017161-lcqrd4v0	455	123	Variable	variable	JJ
cord-017161-lcqrd4v0	455	124	expression	expression	NN
cord-017161-lcqrd4v0	455	125	of	of	IN
cord-017161-lcqrd4v0	455	126	Lactobacillus	lactobacillus	NN
cord-017161-lcqrd4v0	455	127	casei	casei	NN
cord-017161-lcqrd4v0	455	128	cell	cell	NN
cord-017161-lcqrd4v0	455	129	wall	wall	NN
cord-017161-lcqrd4v0	455	130	-	-	HYPH
cord-017161-lcqrd4v0	455	131	induced	induce	VBN
cord-017161-lcqrd4v0	455	132	coronary	coronary	JJ
cord-017161-lcqrd4v0	455	133	arteritis	arteritis	NN
cord-017161-lcqrd4v0	455	134	:	:	:
cord-017161-lcqrd4v0	455	135	an	an	DT
cord-017161-lcqrd4v0	455	136	animal	animal	NN
cord-017161-lcqrd4v0	455	137	model	model	NN
cord-017161-lcqrd4v0	455	138	of	of	IN
cord-017161-lcqrd4v0	455	139	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	455	140	's	's	POS
cord-017161-lcqrd4v0	455	141	disease	disease	NN
cord-017161-lcqrd4v0	455	142	in	in	IN
cord-017161-lcqrd4v0	455	143	selected	select	VBN
cord-017161-lcqrd4v0	455	144	inbred	inbred	JJ
cord-017161-lcqrd4v0	455	145	mouse	mouse	NN
cord-017161-lcqrd4v0	455	146	strains	strain	NNS
cord-017161-lcqrd4v0	455	147	Presence	Presence	NNP
cord-017161-lcqrd4v0	455	148	of	of	IN
cord-017161-lcqrd4v0	455	149	IFN	IFN	NNP
cord-017161-lcqrd4v0	455	150	-	-	HYPH
cord-017161-lcqrd4v0	455	151	g	g	NNP
cord-017161-lcqrd4v0	455	152	does	do	VBZ
cord-017161-lcqrd4v0	455	153	not	not	RB
cord-017161-lcqrd4v0	455	154	indicate	indicate	VB
cord-017161-lcqrd4v0	455	155	its	-PRON-	PRP$
cord-017161-lcqrd4v0	455	156	necessity	necessity	NN
cord-017161-lcqrd4v0	455	157	for	for	IN
cord-017161-lcqrd4v0	455	158	induction	induction	NN
cord-017161-lcqrd4v0	455	159	of	of	IN
cord-017161-lcqrd4v0	455	160	coronary	coronary	JJ
cord-017161-lcqrd4v0	455	161	arteritis	arteritis	NN
cord-017161-lcqrd4v0	455	162	in	in	IN
cord-017161-lcqrd4v0	455	163	an	an	DT
cord-017161-lcqrd4v0	455	164	animal	animal	NN
cord-017161-lcqrd4v0	455	165	model	model	NN
cord-017161-lcqrd4v0	455	166	of	of	IN
cord-017161-lcqrd4v0	455	167	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	455	168	disease	disease	NN
cord-017161-lcqrd4v0	455	169	TNF	TNF	NNP
cord-017161-lcqrd4v0	455	170	-	-	HYPH
cord-017161-lcqrd4v0	455	171	g	g	NNP
cord-017161-lcqrd4v0	455	172	is	be	VBZ
cord-017161-lcqrd4v0	455	173	necessary	necessary	JJ
cord-017161-lcqrd4v0	455	174	for	for	IN
cord-017161-lcqrd4v0	455	175	induction	induction	NN
cord-017161-lcqrd4v0	455	176	of	of	IN
cord-017161-lcqrd4v0	455	177	coronary	coronary	JJ
cord-017161-lcqrd4v0	455	178	artery	artery	NN
cord-017161-lcqrd4v0	455	179	in	in	IN
cord-017161-lcqrd4v0	455	180	fl	fl	NNP
cord-017161-lcqrd4v0	455	181	ammation	ammation	NNP
cord-017161-lcqrd4v0	455	182	and	and	CC
cord-017161-lcqrd4v0	455	183	aneurysm	aneurysm	NN
cord-017161-lcqrd4v0	455	184	formation	formation	NN
cord-017161-lcqrd4v0	455	185	in	in	IN
cord-017161-lcqrd4v0	455	186	an	an	DT
cord-017161-lcqrd4v0	455	187	animal	animal	NN
cord-017161-lcqrd4v0	455	188	model	model	NN
cord-017161-lcqrd4v0	455	189	of	of	IN
cord-017161-lcqrd4v0	455	190	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	455	191	disease	disease	NN
cord-017161-lcqrd4v0	455	192	Involvement	Involvement	NNP
cord-017161-lcqrd4v0	455	193	of	of	IN
cord-017161-lcqrd4v0	455	194	innate	innate	JJ
cord-017161-lcqrd4v0	455	195	and	and	CC
cord-017161-lcqrd4v0	455	196	adaptive	adaptive	JJ
cord-017161-lcqrd4v0	455	197	immunity	immunity	NN
cord-017161-lcqrd4v0	455	198	in	in	IN
cord-017161-lcqrd4v0	455	199	a	a	DT
cord-017161-lcqrd4v0	455	200	murine	murine	JJ
cord-017161-lcqrd4v0	455	201	model	model	NN
cord-017161-lcqrd4v0	455	202	of	of	IN
cord-017161-lcqrd4v0	455	203	coronary	coronary	JJ
cord-017161-lcqrd4v0	455	204	arteritis	arteritis	NN
cord-017161-lcqrd4v0	455	205	mimicking	mimic	VBG
cord-017161-lcqrd4v0	455	206	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	455	207	disease	disease	NN
cord-017161-lcqrd4v0	456	1	The	the	DT
cord-017161-lcqrd4v0	456	2	role	role	NN
cord-017161-lcqrd4v0	456	3	of	of	IN
cord-017161-lcqrd4v0	456	4	co	co	NN
cord-017161-lcqrd4v0	456	5	-	-	NN
cord-017161-lcqrd4v0	456	6	stimulation	stimulation	NN
cord-017161-lcqrd4v0	456	7	in	in	IN
cord-017161-lcqrd4v0	456	8	sustaining	sustain	VBG
cord-017161-lcqrd4v0	456	9	the	the	DT
cord-017161-lcqrd4v0	456	10	immune	immune	JJ
cord-017161-lcqrd4v0	456	11	response	response	NN
cord-017161-lcqrd4v0	456	12	in	in	IN
cord-017161-lcqrd4v0	456	13	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	456	14	disease	disease	NN
cord-017161-lcqrd4v0	457	1	The	the	DT
cord-017161-lcqrd4v0	457	2	role	role	NN
cord-017161-lcqrd4v0	457	3	of	of	IN
cord-017161-lcqrd4v0	457	4	toll	toll	NN
cord-017161-lcqrd4v0	457	5	-	-	HYPH
cord-017161-lcqrd4v0	457	6	like	like	JJ
cord-017161-lcqrd4v0	457	7	receptor	receptor	NN
cord-017161-lcqrd4v0	457	8	2	2	CD
cord-017161-lcqrd4v0	457	9	(	(	-LRB-
cord-017161-lcqrd4v0	457	10	TLR2	TLR2	NNP
cord-017161-lcqrd4v0	457	11	)	)	-RRB-
cord-017161-lcqrd4v0	457	12	in	in	IN
cord-017161-lcqrd4v0	457	13	an	an	DT
cord-017161-lcqrd4v0	457	14	animal	animal	NN
cord-017161-lcqrd4v0	457	15	model	model	NN
cord-017161-lcqrd4v0	457	16	of	of	IN
cord-017161-lcqrd4v0	457	17	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	457	18	disease	disease	NN
cord-017161-lcqrd4v0	457	19	TLR2	TLR2	NNP
cord-017161-lcqrd4v0	457	20	and	and	CC
cord-017161-lcqrd4v0	457	21	MyD88	MyD88	NNPS
cord-017161-lcqrd4v0	457	22	contribute	contribute	VBP
cord-017161-lcqrd4v0	457	23	to	to	IN
cord-017161-lcqrd4v0	457	24	Lactobacillus	lactobacillus	NN
cord-017161-lcqrd4v0	457	25	casei	casei	NN
cord-017161-lcqrd4v0	457	26	extract	extract	NN
cord-017161-lcqrd4v0	457	27	-	-	HYPH
cord-017161-lcqrd4v0	457	28	induced	induce	VBN
cord-017161-lcqrd4v0	457	29	focal	focal	JJ
cord-017161-lcqrd4v0	457	30	coronary	coronary	JJ
cord-017161-lcqrd4v0	457	31	arteritis	arteritis	NN
cord-017161-lcqrd4v0	457	32	in	in	IN
cord-017161-lcqrd4v0	457	33	a	a	DT
cord-017161-lcqrd4v0	457	34	mouse	mouse	NN
cord-017161-lcqrd4v0	457	35	model	model	NN
cord-017161-lcqrd4v0	457	36	of	of	IN
cord-017161-lcqrd4v0	457	37	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	457	38	disease	disease	NN
cord-017161-lcqrd4v0	457	39	Matrix	Matrix	NNP
cord-017161-lcqrd4v0	457	40	metalloproteinase	metalloproteinase	NN
cord-017161-lcqrd4v0	457	41	9	9	CD
cord-017161-lcqrd4v0	457	42	activity	activity	NN
cord-017161-lcqrd4v0	457	43	leads	lead	VBZ
cord-017161-lcqrd4v0	457	44	to	to	IN
cord-017161-lcqrd4v0	457	45	elastin	elastin	NN
cord-017161-lcqrd4v0	457	46	breakdown	breakdown	NN
cord-017161-lcqrd4v0	457	47	in	in	IN
cord-017161-lcqrd4v0	457	48	an	an	DT
cord-017161-lcqrd4v0	457	49	animal	animal	NN
cord-017161-lcqrd4v0	457	50	model	model	NN
cord-017161-lcqrd4v0	457	51	of	of	IN
cord-017161-lcqrd4v0	457	52	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	457	53	disease	disease	NN
cord-017161-lcqrd4v0	457	54	Inhibition	inhibition	NN
cord-017161-lcqrd4v0	457	55	of	of	IN
cord-017161-lcqrd4v0	457	56	transforming	transform	VBG
cord-017161-lcqrd4v0	457	57	growth	growth	NN
cord-017161-lcqrd4v0	457	58	factor	factor	NN
cord-017161-lcqrd4v0	457	59	b	b	.
cord-017161-lcqrd4v0	458	1	worsens	worsen	VBZ
cord-017161-lcqrd4v0	458	2	elastin	elastin	NN
cord-017161-lcqrd4v0	458	3	degradation	degradation	NN
cord-017161-lcqrd4v0	458	4	in	in	IN
cord-017161-lcqrd4v0	458	5	a	a	DT
cord-017161-lcqrd4v0	458	6	murine	murine	JJ
cord-017161-lcqrd4v0	458	7	model	model	NN
cord-017161-lcqrd4v0	458	8	of	of	IN
cord-017161-lcqrd4v0	458	9	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	458	10	disease	disease	NN
cord-017161-lcqrd4v0	458	11	ITPKC	ITPKC	NNP
cord-017161-lcqrd4v0	458	12	functional	functional	JJ
cord-017161-lcqrd4v0	458	13	polymorphism	polymorphism	NN
cord-017161-lcqrd4v0	458	14	associated	associate	VBN
cord-017161-lcqrd4v0	458	15	with	with	IN
cord-017161-lcqrd4v0	458	16	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	458	17	disease	disease	NN
cord-017161-lcqrd4v0	458	18	susceptibility	susceptibility	NN
cord-017161-lcqrd4v0	458	19	and	and	CC
cord-017161-lcqrd4v0	458	20	formation	formation	NN
cord-017161-lcqrd4v0	458	21	of	of	IN
cord-017161-lcqrd4v0	458	22	coronary	coronary	JJ
cord-017161-lcqrd4v0	458	23	artery	artery	NN
cord-017161-lcqrd4v0	458	24	aneurysms	aneurysm	NNS
cord-017161-lcqrd4v0	458	25	Association	Association	NNP
cord-017161-lcqrd4v0	458	26	of	of	IN
cord-017161-lcqrd4v0	458	27	mannose	mannose	NN
cord-017161-lcqrd4v0	458	28	-	-	HYPH
cord-017161-lcqrd4v0	458	29	binding	bind	VBG
cord-017161-lcqrd4v0	458	30	lectin	lectin	NN
cord-017161-lcqrd4v0	458	31	genotype	genotype	NN
cord-017161-lcqrd4v0	458	32	with	with	IN
cord-017161-lcqrd4v0	458	33	cardiovascular	cardiovascular	JJ
cord-017161-lcqrd4v0	458	34	abnormalities	abnormality	NNS
cord-017161-lcqrd4v0	458	35	in	in	IN
cord-017161-lcqrd4v0	458	36	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	458	37	disease	disease	NN
cord-017161-lcqrd4v0	458	38	Insertion	insertion	NN
cord-017161-lcqrd4v0	458	39	/	/	SYM
cord-017161-lcqrd4v0	458	40	deletion	deletion	NN
cord-017161-lcqrd4v0	458	41	polymorphism	polymorphism	NN
cord-017161-lcqrd4v0	458	42	of	of	IN
cord-017161-lcqrd4v0	458	43	angiotensin	angiotensin	NN
cord-017161-lcqrd4v0	458	44	converting	convert	VBG
cord-017161-lcqrd4v0	458	45	enzyme	enzyme	NN
cord-017161-lcqrd4v0	458	46	gene	gene	NN
cord-017161-lcqrd4v0	458	47	in	in	IN
cord-017161-lcqrd4v0	458	48	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	458	49	disease	disease	NN
cord-017161-lcqrd4v0	458	50	Polymorphism	polymorphism	NN
cord-017161-lcqrd4v0	458	51	of	of	IN
cord-017161-lcqrd4v0	458	52	matrix	matrix	NNP
cord-017161-lcqrd4v0	458	53	metalloproteinase-3	metalloproteinase-3	NNP
cord-017161-lcqrd4v0	458	54	promoter	promoter	NN
cord-017161-lcqrd4v0	458	55	gene	gene	NN
cord-017161-lcqrd4v0	458	56	as	as	IN
cord-017161-lcqrd4v0	458	57	a	a	DT
cord-017161-lcqrd4v0	458	58	risk	risk	NN
cord-017161-lcqrd4v0	458	59	factor	factor	NN
cord-017161-lcqrd4v0	458	60	for	for	IN
cord-017161-lcqrd4v0	458	61	coronary	coronary	JJ
cord-017161-lcqrd4v0	458	62	artery	artery	NN
cord-017161-lcqrd4v0	458	63	lesions	lesion	NNS
cord-017161-lcqrd4v0	458	64	in	in	IN
cord-017161-lcqrd4v0	458	65	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	458	66	disease	disease	NN
cord-017161-lcqrd4v0	458	67	Matrix	Matrix	NNP
cord-017161-lcqrd4v0	458	68	metalloproteinase	metalloproteinase	NN
cord-017161-lcqrd4v0	458	69	haplotypes	haplotype	NNS
cord-017161-lcqrd4v0	458	70	associated	associate	VBN
cord-017161-lcqrd4v0	458	71	with	with	IN
cord-017161-lcqrd4v0	458	72	coronary	coronary	JJ
cord-017161-lcqrd4v0	458	73	artery	artery	NN
cord-017161-lcqrd4v0	458	74	aneurysm	aneurysm	NN
cord-017161-lcqrd4v0	458	75	formation	formation	NN
cord-017161-lcqrd4v0	458	76	in	in	IN
cord-017161-lcqrd4v0	458	77	patients	patient	NNS
cord-017161-lcqrd4v0	458	78	with	with	IN
cord-017161-lcqrd4v0	458	79	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	458	80	disease	disease	NN
cord-017161-lcqrd4v0	458	81	Association	Association	NNP
cord-017161-lcqrd4v0	458	82	of	of	IN
cord-017161-lcqrd4v0	458	83	IL	IL	NNP
cord-017161-lcqrd4v0	458	84	1Ra	1ra	JJ
cord-017161-lcqrd4v0	458	85	gene	gene	NN
cord-017161-lcqrd4v0	458	86	polymorphism	polymorphism	NN
cord-017161-lcqrd4v0	458	87	,	,	,
cord-017161-lcqrd4v0	458	88	but	but	CC
cord-017161-lcqrd4v0	458	89	no	no	DT
cord-017161-lcqrd4v0	458	90	association	association	NN
cord-017161-lcqrd4v0	458	91	of	of	IN
cord-017161-lcqrd4v0	458	92	IL	IL	NNP
cord-017161-lcqrd4v0	458	93	1	1	CD
cord-017161-lcqrd4v0	458	94	and	and	CC
cord-017161-lcqrd4v0	458	95	IL	IL	NNP
cord-017161-lcqrd4v0	458	96	4	4	CD
cord-017161-lcqrd4v0	458	97	gene	gene	NN
cord-017161-lcqrd4v0	458	98	polymorphisms	polymorphism	NNS
cord-017161-lcqrd4v0	458	99	,	,	,
cord-017161-lcqrd4v0	458	100	with	with	IN
cord-017161-lcqrd4v0	458	101	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	458	102	disease	disease	NN
cord-017161-lcqrd4v0	459	1	In	in	IN
cord-017161-lcqrd4v0	459	2	fl	fl	NNP
cord-017161-lcqrd4v0	459	3	uence	uence	NN
cord-017161-lcqrd4v0	459	4	of	of	IN
cord-017161-lcqrd4v0	459	5	interleukin	interleukin	NN
cord-017161-lcqrd4v0	459	6	18	18	CD
cord-017161-lcqrd4v0	459	7	promoter	promoter	NN
cord-017161-lcqrd4v0	459	8	polymorphisms	polymorphism	NNS
cord-017161-lcqrd4v0	459	9	in	in	IN
cord-017161-lcqrd4v0	459	10	susceptibility	susceptibility	NN
cord-017161-lcqrd4v0	459	11	to	to	IN
cord-017161-lcqrd4v0	459	12	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	459	13	disease	disease	NN
cord-017161-lcqrd4v0	459	14	in	in	IN
cord-017161-lcqrd4v0	459	15	Taiwan	Taiwan	NNP
cord-017161-lcqrd4v0	460	1	The	the	DT
cord-017161-lcqrd4v0	460	2	correlation	correlation	NN
cord-017161-lcqrd4v0	460	3	between	between	IN
cord-017161-lcqrd4v0	460	4	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	460	5	disease	disease	NN
cord-017161-lcqrd4v0	460	6	and	and	CC
cord-017161-lcqrd4v0	460	7	polymorphisms	polymorphism	NNS
cord-017161-lcqrd4v0	460	8	of	of	IN
cord-017161-lcqrd4v0	460	9	tumor	tumor	NN
cord-017161-lcqrd4v0	460	10	necrosis	necrosis	NN
cord-017161-lcqrd4v0	460	11	factor	factor	NN
cord-017161-lcqrd4v0	460	12	alpha	alpha	NN
cord-017161-lcqrd4v0	460	13	and	and	CC
cord-017161-lcqrd4v0	460	14	interleukin-10	interleukin-10	NNP
cord-017161-lcqrd4v0	460	15	gene	gene	NNP
cord-017161-lcqrd4v0	460	16	promoter	promoter	NNP
cord-017161-lcqrd4v0	460	17	Association	Association	NNP
cord-017161-lcqrd4v0	460	18	of	of	IN
cord-017161-lcqrd4v0	460	19	vascular	vascular	JJ
cord-017161-lcqrd4v0	460	20	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	460	21	growth	growth	NN
cord-017161-lcqrd4v0	460	22	factor	factor	NN
cord-017161-lcqrd4v0	460	23	(	(	-LRB-
cord-017161-lcqrd4v0	460	24	VEGF	VEGF	NNP
cord-017161-lcqrd4v0	460	25	)	)	-RRB-
cord-017161-lcqrd4v0	460	26	and	and	CC
cord-017161-lcqrd4v0	460	27	VEGF	VEGF	NNP
cord-017161-lcqrd4v0	460	28	receptor	receptor	NN
cord-017161-lcqrd4v0	460	29	gene	gene	NN
cord-017161-lcqrd4v0	460	30	polymorphisms	polymorphism	NNS
cord-017161-lcqrd4v0	460	31	with	with	IN
cord-017161-lcqrd4v0	460	32	coronary	coronary	JJ
cord-017161-lcqrd4v0	460	33	artery	artery	NN
cord-017161-lcqrd4v0	460	34	lesions	lesion	NNS
cord-017161-lcqrd4v0	460	35	of	of	IN
cord-017161-lcqrd4v0	460	36	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	460	37	disease	disease	NN
cord-017161-lcqrd4v0	460	38	Genetic	genetic	JJ
cord-017161-lcqrd4v0	460	39	variations	variation	NNS
cord-017161-lcqrd4v0	460	40	in	in	IN
cord-017161-lcqrd4v0	460	41	the	the	DT
cord-017161-lcqrd4v0	460	42	receptor	receptor	NN
cord-017161-lcqrd4v0	460	43	-	-	HYPH
cord-017161-lcqrd4v0	460	44	ligand	ligand	NN
cord-017161-lcqrd4v0	460	45	pair	pair	NN
cord-017161-lcqrd4v0	460	46	CCR5	CCR5	NNP
cord-017161-lcqrd4v0	460	47	and	and	CC
cord-017161-lcqrd4v0	460	48	CCL3L1	CCL3L1	NNP
cord-017161-lcqrd4v0	460	49	are	be	VBP
cord-017161-lcqrd4v0	460	50	important	important	JJ
cord-017161-lcqrd4v0	460	51	determinants	determinant	NNS
cord-017161-lcqrd4v0	460	52	of	of	IN
cord-017161-lcqrd4v0	460	53	susceptibility	susceptibility	NN
cord-017161-lcqrd4v0	460	54	to	to	IN
cord-017161-lcqrd4v0	460	55	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	460	56	disease	disease	NN
cord-017161-lcqrd4v0	460	57	Inducible	inducible	JJ
cord-017161-lcqrd4v0	460	58	and	and	CC
cord-017161-lcqrd4v0	460	59	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	460	60	constitutive	constitutive	JJ
cord-017161-lcqrd4v0	460	61	nitric	nitric	NN
cord-017161-lcqrd4v0	460	62	oxide	oxide	NN
cord-017161-lcqrd4v0	460	63	synthase	synthase	NN
cord-017161-lcqrd4v0	460	64	gene	gene	NN
cord-017161-lcqrd4v0	460	65	polymorphisms	polymorphism	NNS
cord-017161-lcqrd4v0	460	66	in	in	IN
cord-017161-lcqrd4v0	460	67	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	460	68	disease	disease	NN
cord-017161-lcqrd4v0	461	1	The	the	DT
cord-017161-lcqrd4v0	461	2	involvement	involvement	NN
cord-017161-lcqrd4v0	461	3	of	of	IN
cord-017161-lcqrd4v0	461	4	Fc	Fc	NNP
cord-017161-lcqrd4v0	461	5	gamma	gamma	NN
cord-017161-lcqrd4v0	461	6	receptor	receptor	NN
cord-017161-lcqrd4v0	461	7	gene	gene	NN
cord-017161-lcqrd4v0	461	8	polymorphisms	polymorphism	NNS
cord-017161-lcqrd4v0	461	9	in	in	IN
cord-017161-lcqrd4v0	461	10	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	461	11	disease	disease	NN
cord-017161-lcqrd4v0	462	1	ITPKC	ITPKC	NNP
cord-017161-lcqrd4v0	462	2	gene	gene	NN
cord-017161-lcqrd4v0	462	3	SNP	SNP	NNP
cord-017161-lcqrd4v0	462	4	rs28493229	rs28493229	NNP
cord-017161-lcqrd4v0	462	5	and	and	CC
cord-017161-lcqrd4v0	462	6	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	462	7	disease	disease	NN
cord-017161-lcqrd4v0	462	8	in	in	IN
cord-017161-lcqrd4v0	462	9	Taiwanese	taiwanese	JJ
cord-017161-lcqrd4v0	462	10	children	child	NNS
cord-017161-lcqrd4v0	463	1	Common	common	JJ
cord-017161-lcqrd4v0	463	2	variants	variant	NNS
cord-017161-lcqrd4v0	463	3	in	in	IN
cord-017161-lcqrd4v0	463	4	CASP3	CASP3	NNP
cord-017161-lcqrd4v0	463	5	confer	confer	VB
cord-017161-lcqrd4v0	463	6	susceptibility	susceptibility	NN
cord-017161-lcqrd4v0	463	7	to	to	IN
cord-017161-lcqrd4v0	463	8	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	463	9	disease	disease	NN
cord-017161-lcqrd4v0	463	10	CASP3	CASP3	NNP
cord-017161-lcqrd4v0	463	11	gene	gene	NN
cord-017161-lcqrd4v0	463	12	single	single	JJ
cord-017161-lcqrd4v0	463	13	-	-	HYPH
cord-017161-lcqrd4v0	463	14	nucleotide	nucleotide	JJ
cord-017161-lcqrd4v0	463	15	polymorphism	polymorphism	NN
cord-017161-lcqrd4v0	463	16	(	(	-LRB-
cord-017161-lcqrd4v0	463	17	rs72689236	rs72689236	NN
cord-017161-lcqrd4v0	463	18	)	)	-RRB-
cord-017161-lcqrd4v0	463	19	and	and	CC
cord-017161-lcqrd4v0	463	20	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	463	21	disease	disease	NN
cord-017161-lcqrd4v0	463	22	in	in	IN
cord-017161-lcqrd4v0	463	23	Taiwanese	taiwanese	JJ
cord-017161-lcqrd4v0	463	24	children	child	NNS
cord-017161-lcqrd4v0	463	25	Association	Association	NNP
cord-017161-lcqrd4v0	463	26	of	of	IN
cord-017161-lcqrd4v0	463	27	COL11A2	COL11A2	NNP
cord-017161-lcqrd4v0	463	28	polymorphism	polymorphism	NN
cord-017161-lcqrd4v0	463	29	with	with	IN
cord-017161-lcqrd4v0	463	30	susceptibility	susceptibility	NN
cord-017161-lcqrd4v0	463	31	to	to	IN
cord-017161-lcqrd4v0	463	32	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	463	33	disease	disease	NN
cord-017161-lcqrd4v0	463	34	and	and	CC
cord-017161-lcqrd4v0	463	35	development	development	NN
cord-017161-lcqrd4v0	463	36	of	of	IN
cord-017161-lcqrd4v0	463	37	coronary	coronary	JJ
cord-017161-lcqrd4v0	463	38	artery	artery	NN
cord-017161-lcqrd4v0	463	39	lesions	lesion	NNS
cord-017161-lcqrd4v0	464	1	Single	single	JJ
cord-017161-lcqrd4v0	464	2	nucleotide	nucleotide	JJ
cord-017161-lcqrd4v0	464	3	polymorphism	polymorphism	NN
cord-017161-lcqrd4v0	465	1	rs2229634	rs2229634	NNP
cord-017161-lcqrd4v0	465	2	in	in	IN
cord-017161-lcqrd4v0	465	3	the	the	DT
cord-017161-lcqrd4v0	465	4	ITPR3	ITPR3	``
cord-017161-lcqrd4v0	465	5	gene	gene	NN
cord-017161-lcqrd4v0	465	6	is	be	VBZ
cord-017161-lcqrd4v0	465	7	associated	associate	VBN
cord-017161-lcqrd4v0	465	8	with	with	IN
cord-017161-lcqrd4v0	465	9	the	the	DT
cord-017161-lcqrd4v0	465	10	risk	risk	NN
cord-017161-lcqrd4v0	465	11	of	of	IN
cord-017161-lcqrd4v0	465	12	developing	develop	VBG
cord-017161-lcqrd4v0	465	13	coronary	coronary	JJ
cord-017161-lcqrd4v0	465	14	artery	artery	NN
cord-017161-lcqrd4v0	465	15	aneurysm	aneurysm	NN
cord-017161-lcqrd4v0	465	16	in	in	IN
cord-017161-lcqrd4v0	465	17	children	child	NNS
cord-017161-lcqrd4v0	465	18	with	with	IN
cord-017161-lcqrd4v0	465	19	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	465	20	disease	disease	NN
cord-017161-lcqrd4v0	466	1	A	a	DT
cord-017161-lcqrd4v0	466	2	genomewide	genomewide	NN
cord-017161-lcqrd4v0	466	3	linkage	linkage	NN
cord-017161-lcqrd4v0	466	4	analysis	analysis	NN
cord-017161-lcqrd4v0	466	5	of	of	IN
cord-017161-lcqrd4v0	466	6	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	466	7	disease	disease	NN
cord-017161-lcqrd4v0	466	8	:	:	:
cord-017161-lcqrd4v0	466	9	evidence	evidence	NN
cord-017161-lcqrd4v0	466	10	for	for	IN
cord-017161-lcqrd4v0	466	11	linkage	linkage	NN
cord-017161-lcqrd4v0	466	12	to	to	IN
cord-017161-lcqrd4v0	466	13	chromosome	chromosome	NN
cord-017161-lcqrd4v0	466	14	12	12	CD
cord-017161-lcqrd4v0	467	1	A	a	DT
cord-017161-lcqrd4v0	467	2	genome	genome	NN
cord-017161-lcqrd4v0	467	3	-	-	HYPH
cord-017161-lcqrd4v0	467	4	wide	wide	JJ
cord-017161-lcqrd4v0	467	5	association	association	NN
cord-017161-lcqrd4v0	467	6	study	study	NN
cord-017161-lcqrd4v0	468	1	identi	identi	NNP
cord-017161-lcqrd4v0	468	2	fi	fi	NNP
cord-017161-lcqrd4v0	469	1	es	es	XX
cord-017161-lcqrd4v0	470	1	novel	novel	JJ
cord-017161-lcqrd4v0	470	2	and	and	CC
cord-017161-lcqrd4v0	470	3	functionally	functionally	RB
cord-017161-lcqrd4v0	470	4	related	related	JJ
cord-017161-lcqrd4v0	470	5	susceptibility	susceptibility	NN
cord-017161-lcqrd4v0	470	6	loci	locus	NNS
cord-017161-lcqrd4v0	470	7	for	for	IN
cord-017161-lcqrd4v0	470	8	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	470	9	disease	disease	NN
cord-017161-lcqrd4v0	470	10	Research	Research	NNP
cord-017161-lcqrd4v0	470	11	Committee	Committee	NNP
cord-017161-lcqrd4v0	470	12	Diagnostic	Diagnostic	NNP
cord-017161-lcqrd4v0	470	13	Guidelines	Guidelines	NNPS
cord-017161-lcqrd4v0	470	14	for	for	IN
cord-017161-lcqrd4v0	470	15	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	470	16	Disease	Disease	NNP
cord-017161-lcqrd4v0	470	17	Update	Update	NNP
cord-017161-lcqrd4v0	470	18	on	on	IN
cord-017161-lcqrd4v0	470	19	childhood	childhood	NN
cord-017161-lcqrd4v0	470	20	vasculitides	vasculitide	NNS
cord-017161-lcqrd4v0	470	21	Prevalence	prevalence	NN
cord-017161-lcqrd4v0	470	22	of	of	IN
cord-017161-lcqrd4v0	470	23	coronary	coronary	JJ
cord-017161-lcqrd4v0	470	24	artery	artery	NN
cord-017161-lcqrd4v0	470	25	abnormalities	abnormality	NNS
cord-017161-lcqrd4v0	470	26	in	in	IN
cord-017161-lcqrd4v0	470	27	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	470	28	disease	disease	NN
cord-017161-lcqrd4v0	470	29	is	be	VBZ
cord-017161-lcqrd4v0	470	30	highly	highly	RB
cord-017161-lcqrd4v0	470	31	dependent	dependent	JJ
cord-017161-lcqrd4v0	470	32	on	on	IN
cord-017161-lcqrd4v0	470	33	gamma	gamma	NN
cord-017161-lcqrd4v0	470	34	globulin	globulin	NN
cord-017161-lcqrd4v0	470	35	dose	dose	NN
cord-017161-lcqrd4v0	470	36	but	but	CC
cord-017161-lcqrd4v0	470	37	independent	independent	JJ
cord-017161-lcqrd4v0	470	38	of	of	IN
cord-017161-lcqrd4v0	470	39	salicylate	salicylate	NN
cord-017161-lcqrd4v0	470	40	dose	dose	NN
cord-017161-lcqrd4v0	471	1	The	the	DT
cord-017161-lcqrd4v0	471	2	prevention	prevention	NN
cord-017161-lcqrd4v0	471	3	of	of	IN
cord-017161-lcqrd4v0	471	4	coronary	coronary	JJ
cord-017161-lcqrd4v0	471	5	artery	artery	NN
cord-017161-lcqrd4v0	471	6	aneurysm	aneurysm	NN
cord-017161-lcqrd4v0	471	7	in	in	IN
cord-017161-lcqrd4v0	471	8	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	471	9	disease	disease	NN
cord-017161-lcqrd4v0	471	10	:	:	:
cord-017161-lcqrd4v0	471	11	a	a	DT
cord-017161-lcqrd4v0	471	12	meta	meta	NN
cord-017161-lcqrd4v0	471	13	-	-	HYPH
cord-017161-lcqrd4v0	471	14	analysis	analysis	NN
cord-017161-lcqrd4v0	471	15	on	on	IN
cord-017161-lcqrd4v0	471	16	the	the	DT
cord-017161-lcqrd4v0	471	17	ef	ef	NNP
cord-017161-lcqrd4v0	471	18	fi	fi	NN
cord-017161-lcqrd4v0	471	19	cacy	cacy	NN
cord-017161-lcqrd4v0	471	20	of	of	IN
cord-017161-lcqrd4v0	471	21	aspirin	aspirin	NN
cord-017161-lcqrd4v0	471	22	and	and	CC
cord-017161-lcqrd4v0	471	23	immunoglobulin	immunoglobulin	NN
cord-017161-lcqrd4v0	471	24	treatment	treatment	NN
cord-017161-lcqrd4v0	471	25	A	a	DT
cord-017161-lcqrd4v0	471	26	multicenter	multicenter	JJ
cord-017161-lcqrd4v0	471	27	prospective	prospective	JJ
cord-017161-lcqrd4v0	471	28	randomized	randomized	JJ
cord-017161-lcqrd4v0	471	29	trial	trial	NN
cord-017161-lcqrd4v0	471	30	of	of	IN
cord-017161-lcqrd4v0	471	31	corticosteroids	corticosteroid	NNS
cord-017161-lcqrd4v0	471	32	in	in	IN
cord-017161-lcqrd4v0	471	33	primary	primary	JJ
cord-017161-lcqrd4v0	471	34	therapy	therapy	NN
cord-017161-lcqrd4v0	471	35	for	for	IN
cord-017161-lcqrd4v0	471	36	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	471	37	disease	disease	NN
cord-017161-lcqrd4v0	471	38	:	:	:
cord-017161-lcqrd4v0	471	39	clinical	clinical	JJ
cord-017161-lcqrd4v0	471	40	course	course	NN
cord-017161-lcqrd4v0	471	41	and	and	CC
cord-017161-lcqrd4v0	471	42	coronary	coronary	JJ
cord-017161-lcqrd4v0	471	43	artery	artery	NN
cord-017161-lcqrd4v0	471	44	outcome	outcome	NN
cord-017161-lcqrd4v0	472	1	Randomized	randomized	JJ
cord-017161-lcqrd4v0	472	2	trial	trial	NN
cord-017161-lcqrd4v0	472	3	of	of	IN
cord-017161-lcqrd4v0	472	4	pulsed	pulse	VBN
cord-017161-lcqrd4v0	472	5	corticosteroid	corticosteroid	NN
cord-017161-lcqrd4v0	472	6	therapy	therapy	NN
cord-017161-lcqrd4v0	472	7	for	for	IN
cord-017161-lcqrd4v0	472	8	primary	primary	JJ
cord-017161-lcqrd4v0	472	9	treatment	treatment	NN
cord-017161-lcqrd4v0	472	10	of	of	IN
cord-017161-lcqrd4v0	472	11	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	472	12	disease	disease	NN
cord-017161-lcqrd4v0	473	1	In	in	IN
cord-017161-lcqrd4v0	473	2	fl	fl	NNP
cord-017161-lcqrd4v0	473	3	iximab	iximab	NNS
cord-017161-lcqrd4v0	473	4	treatment	treatment	NN
cord-017161-lcqrd4v0	473	5	for	for	IN
cord-017161-lcqrd4v0	473	6	refractory	refractory	JJ
cord-017161-lcqrd4v0	473	7	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	473	8	syndrome	syndrome	NN
cord-017161-lcqrd4v0	474	1	In	in	IN
cord-017161-lcqrd4v0	474	2	fl	fl	NNP
cord-017161-lcqrd4v0	474	3	iximab	iximab	NNS
cord-017161-lcqrd4v0	474	4	treatment	treatment	NN
cord-017161-lcqrd4v0	474	5	of	of	IN
cord-017161-lcqrd4v0	474	6	intravenous	intravenous	JJ
cord-017161-lcqrd4v0	474	7	immunoglobulinresistant	immunoglobulinresistant	NN
cord-017161-lcqrd4v0	474	8	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	474	9	disease	disease	NN
cord-017161-lcqrd4v0	474	10	Update	update	NN
cord-017161-lcqrd4v0	474	11	on	on	IN
cord-017161-lcqrd4v0	474	12	the	the	DT
cord-017161-lcqrd4v0	474	13	treatment	treatment	NN
cord-017161-lcqrd4v0	474	14	of	of	IN
cord-017161-lcqrd4v0	474	15	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	474	16	disease	disease	NN
cord-017161-lcqrd4v0	474	17	in	in	IN
cord-017161-lcqrd4v0	474	18	childhood	childhood	NN
cord-017161-lcqrd4v0	474	19	Etanercept	Etanercept	NNP
cord-017161-lcqrd4v0	474	20	as	as	IN
cord-017161-lcqrd4v0	474	21	adjunctive	adjunctive	JJ
cord-017161-lcqrd4v0	474	22	treatment	treatment	NN
cord-017161-lcqrd4v0	474	23	for	for	IN
cord-017161-lcqrd4v0	474	24	acute	acute	JJ
cord-017161-lcqrd4v0	474	25	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	474	26	disease	disease	NN
cord-017161-lcqrd4v0	474	27	:	:	:
cord-017161-lcqrd4v0	474	28	study	study	NN
cord-017161-lcqrd4v0	474	29	design	design	NN
cord-017161-lcqrd4v0	474	30	and	and	CC
cord-017161-lcqrd4v0	474	31	rationale	rationale	NN
cord-017161-lcqrd4v0	474	32	Warfarin	Warfarin	NNP
cord-017161-lcqrd4v0	474	33	therapy	therapy	NN
cord-017161-lcqrd4v0	474	34	for	for	IN
cord-017161-lcqrd4v0	474	35	giant	giant	JJ
cord-017161-lcqrd4v0	474	36	aneurysm	aneurysm	NN
cord-017161-lcqrd4v0	474	37	prevents	prevent	VBZ
cord-017161-lcqrd4v0	474	38	myocardial	myocardial	JJ
cord-017161-lcqrd4v0	474	39	infarction	infarction	NN
cord-017161-lcqrd4v0	474	40	in	in	IN
cord-017161-lcqrd4v0	474	41	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	474	42	disease	disease	NN
cord-017161-lcqrd4v0	474	43	Long	long	JJ
cord-017161-lcqrd4v0	474	44	-	-	HYPH
cord-017161-lcqrd4v0	474	45	term	term	NN
cord-017161-lcqrd4v0	474	46	consequences	consequence	NNS
cord-017161-lcqrd4v0	474	47	of	of	IN
cord-017161-lcqrd4v0	474	48	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	474	49	disease	disease	NN
cord-017161-lcqrd4v0	474	50	:	:	:
cord-017161-lcqrd4v0	475	1	a	a	DT
cord-017161-lcqrd4v0	475	2	10-to	10-to	CD
cord-017161-lcqrd4v0	475	3	21-year	21-year	JJ
cord-017161-lcqrd4v0	475	4	follow	follow	NN
cord-017161-lcqrd4v0	475	5	-	-	HYPH
cord-017161-lcqrd4v0	475	6	up	up	NN
cord-017161-lcqrd4v0	475	7	study	study	NN
cord-017161-lcqrd4v0	475	8	of	of	IN
cord-017161-lcqrd4v0	475	9	594	594	CD
cord-017161-lcqrd4v0	475	10	patients	patient	NNS
cord-017161-lcqrd4v0	475	11	Endothelial	endothelial	JJ
cord-017161-lcqrd4v0	475	12	dysfunction	dysfunction	NN
cord-017161-lcqrd4v0	475	13	late	late	RB
cord-017161-lcqrd4v0	475	14	after	after	IN
cord-017161-lcqrd4v0	475	15	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	475	16	disease	disease	NN
cord-017161-lcqrd4v0	475	17	Mechanisms	Mechanisms	NNPS
cord-017161-lcqrd4v0	475	18	of	of	IN
cord-017161-lcqrd4v0	475	19	disease	disease	NN
cord-017161-lcqrd4v0	475	20	:	:	:
cord-017161-lcqrd4v0	475	21	pathogenesis	pathogenesis	NN
cord-017161-lcqrd4v0	475	22	and	and	CC
cord-017161-lcqrd4v0	475	23	treatment	treatment	NN
cord-017161-lcqrd4v0	475	24	of	of	IN
cord-017161-lcqrd4v0	475	25	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	475	26	-	-	HYPH
cord-017161-lcqrd4v0	475	27	associated	associate	VBN
cord-017161-lcqrd4v0	475	28	vasculitides	vasculitide	NNS
cord-017161-lcqrd4v0	475	29	Nomenclature	nomenclature	NN
cord-017161-lcqrd4v0	475	30	of	of	IN
cord-017161-lcqrd4v0	475	31	systemic	systemic	JJ
cord-017161-lcqrd4v0	475	32	vasculitides	vasculitide	NNS
cord-017161-lcqrd4v0	475	33	Churg	Churg	NNP
cord-017161-lcqrd4v0	475	34	-	-	HYPH
cord-017161-lcqrd4v0	475	35	Strauss	Strauss	NNP
cord-017161-lcqrd4v0	475	36	syndrome	syndrome	NN
cord-017161-lcqrd4v0	475	37	in	in	IN
cord-017161-lcqrd4v0	475	38	children	child	NNS
cord-017161-lcqrd4v0	475	39	:	:	:
cord-017161-lcqrd4v0	475	40	a	a	DT
cord-017161-lcqrd4v0	475	41	clinical	clinical	JJ
cord-017161-lcqrd4v0	475	42	and	and	CC
cord-017161-lcqrd4v0	475	43	pathologic	pathologic	JJ
cord-017161-lcqrd4v0	475	44	review	review	NN
cord-017161-lcqrd4v0	475	45	Pathogenesis	Pathogenesis	NNP
cord-017161-lcqrd4v0	475	46	of	of	IN
cord-017161-lcqrd4v0	475	47	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	475	48	-	-	HYPH
cord-017161-lcqrd4v0	475	49	associated	associate	VBN
cord-017161-lcqrd4v0	475	50	vasculitides	vasculitide	VBZ
cord-017161-lcqrd4v0	475	51	Pathogenesis	Pathogenesis	NNP
cord-017161-lcqrd4v0	475	52	of	of	IN
cord-017161-lcqrd4v0	475	53	vascular	vascular	JJ
cord-017161-lcqrd4v0	475	54	in	in	IN
cord-017161-lcqrd4v0	475	55	fl	fl	NNP
cord-017161-lcqrd4v0	475	56	ammation	ammation	NNP
cord-017161-lcqrd4v0	475	57	by	by	IN
cord-017161-lcqrd4v0	475	58	anti	anti	JJ
cord-017161-lcqrd4v0	475	59	-	-	JJ
cord-017161-lcqrd4v0	475	60	neutrophil	neutrophil	JJ
cord-017161-lcqrd4v0	475	61	cytoplasmic	cytoplasmic	JJ
cord-017161-lcqrd4v0	475	62	antibodies	antibody	NNS
cord-017161-lcqrd4v0	475	63	Anti	anti	JJ
cord-017161-lcqrd4v0	475	64	-	-	JJ
cord-017161-lcqrd4v0	475	65	neutrophil	neutrophil	JJ
cord-017161-lcqrd4v0	475	66	cytoplasmic	cytoplasmic	JJ
cord-017161-lcqrd4v0	475	67	autoantibodies	autoantibody	NNS
cord-017161-lcqrd4v0	475	68	induce	induce	VBP
cord-017161-lcqrd4v0	475	69	neutrophils	neutrophil	NNS
cord-017161-lcqrd4v0	475	70	to	to	IN
cord-017161-lcqrd4v0	475	71	degranulate	degranulate	VB
cord-017161-lcqrd4v0	475	72	and	and	CC
cord-017161-lcqrd4v0	475	73	produce	produce	VB
cord-017161-lcqrd4v0	475	74	oxygen	oxygen	NN
cord-017161-lcqrd4v0	475	75	radicals	radical	NNS
cord-017161-lcqrd4v0	475	76	in	in	IN
cord-017161-lcqrd4v0	475	77	vitro	vitro	FW
cord-017161-lcqrd4v0	475	78	Neutrophil	Neutrophil	NNP
cord-017161-lcqrd4v0	475	79	-	-	HYPH
cord-017161-lcqrd4v0	475	80	activating	activate	VBG
cord-017161-lcqrd4v0	475	81	potential	potential	NN
cord-017161-lcqrd4v0	475	82	of	of	IN
cord-017161-lcqrd4v0	475	83	antineutrophil	antineutrophil	NNP
cord-017161-lcqrd4v0	475	84	cytoplasm	cytoplasm	NNP
cord-017161-lcqrd4v0	475	85	autoantibodies	autoantibody	NNS
cord-017161-lcqrd4v0	475	86	Effect	Effect	NNP
cord-017161-lcqrd4v0	475	87	of	of	IN
cord-017161-lcqrd4v0	475	88	tumor	tumor	NN
cord-017161-lcqrd4v0	475	89	necrosis	necrosis	NN
cord-017161-lcqrd4v0	475	90	factor	factor	NN
cord-017161-lcqrd4v0	475	91	-	-	HYPH
cord-017161-lcqrd4v0	475	92	induced	induce	VBN
cord-017161-lcqrd4v0	475	93	integrin	integrin	NN
cord-017161-lcqrd4v0	475	94	activation	activation	NN
cord-017161-lcqrd4v0	475	95	on	on	IN
cord-017161-lcqrd4v0	475	96	Fc	Fc	NNP
cord-017161-lcqrd4v0	475	97	gamma	gamma	NN
cord-017161-lcqrd4v0	475	98	receptor	receptor	NN
cord-017161-lcqrd4v0	475	99	II	II	NNP
cord-017161-lcqrd4v0	475	100	-	-	HYPH
cord-017161-lcqrd4v0	475	101	mediated	mediate	VBN
cord-017161-lcqrd4v0	475	102	signal	signal	NN
cord-017161-lcqrd4v0	475	103	transduction	transduction	NN
cord-017161-lcqrd4v0	475	104	:	:	:
cord-017161-lcqrd4v0	475	105	relevance	relevance	NN
cord-017161-lcqrd4v0	475	106	for	for	IN
cord-017161-lcqrd4v0	475	107	activation	activation	NN
cord-017161-lcqrd4v0	475	108	of	of	IN
cord-017161-lcqrd4v0	475	109	neutrophils	neutrophil	NNS
cord-017161-lcqrd4v0	475	110	by	by	IN
cord-017161-lcqrd4v0	475	111	anti	anti	JJ
cord-017161-lcqrd4v0	475	112	-	-	JJ
cord-017161-lcqrd4v0	475	113	proteinase	proteinase	JJ
cord-017161-lcqrd4v0	475	114	3	3	CD
cord-017161-lcqrd4v0	475	115	or	or	CC
cord-017161-lcqrd4v0	475	116	anti	anti	JJ
cord-017161-lcqrd4v0	475	117	-	-	JJ
cord-017161-lcqrd4v0	475	118	myeloperoxidase	myeloperoxidase	JJ
cord-017161-lcqrd4v0	475	119	antibodies	antibody	NNS
cord-017161-lcqrd4v0	475	120	Treatment	Treatment	NNP
cord-017161-lcqrd4v0	475	121	of	of	IN
cord-017161-lcqrd4v0	475	122	rolling	roll	VBG
cord-017161-lcqrd4v0	475	123	neutrophils	neutrophil	NNS
cord-017161-lcqrd4v0	475	124	with	with	IN
cord-017161-lcqrd4v0	475	125	antineutrophil	antineutrophil	NNP
cord-017161-lcqrd4v0	475	126	cytoplasmic	cytoplasmic	JJ
cord-017161-lcqrd4v0	475	127	antibodies	antibody	NNS
cord-017161-lcqrd4v0	475	128	causes	cause	VBZ
cord-017161-lcqrd4v0	475	129	conversion	conversion	NN
cord-017161-lcqrd4v0	475	130	to	to	IN
cord-017161-lcqrd4v0	475	131	fi	fi	NN
cord-017161-lcqrd4v0	475	132	rm	rm	NNP
cord-017161-lcqrd4v0	475	133	integrin	integrin	NN
cord-017161-lcqrd4v0	475	134	mediated	mediate	VBN
cord-017161-lcqrd4v0	475	135	adhesion	adhesion	NN
cord-017161-lcqrd4v0	475	136	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	475	137	induces	induce	VBZ
cord-017161-lcqrd4v0	475	138	beta2	beta2	NN
cord-017161-lcqrd4v0	475	139	integrin	integrin	NN
cord-017161-lcqrd4v0	475	140	and	and	CC
cord-017161-lcqrd4v0	475	141	CXC	CXC	NNP
cord-017161-lcqrd4v0	475	142	chemokine	chemokine	NN
cord-017161-lcqrd4v0	475	143	-	-	HYPH
cord-017161-lcqrd4v0	475	144	dependent	dependent	JJ
cord-017161-lcqrd4v0	475	145	neutrophil	neutrophil	NN
cord-017161-lcqrd4v0	475	146	-	-	HYPH
cord-017161-lcqrd4v0	475	147	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	475	148	cell	cell	NN
cord-017161-lcqrd4v0	475	149	interactions	interaction	NNS
cord-017161-lcqrd4v0	475	150	that	that	WDT
cord-017161-lcqrd4v0	475	151	mimic	mimic	VBP
cord-017161-lcqrd4v0	475	152	those	those	DT
cord-017161-lcqrd4v0	475	153	of	of	IN
cord-017161-lcqrd4v0	475	154	highly	highly	RB
cord-017161-lcqrd4v0	475	155	cytokine	cytokine	NN
cord-017161-lcqrd4v0	475	156	-	-	HYPH
cord-017161-lcqrd4v0	475	157	activated	activate	VBN
cord-017161-lcqrd4v0	475	158	endothelium	endothelium	NN
cord-017161-lcqrd4v0	475	159	Expression	expression	NN
cord-017161-lcqrd4v0	475	160	of	of	IN
cord-017161-lcqrd4v0	475	161	intercellular	intercellular	JJ
cord-017161-lcqrd4v0	475	162	adhesion	adhesion	NN
cord-017161-lcqrd4v0	475	163	molecule	molecule	NN
cord-017161-lcqrd4v0	475	164	1	1	CD
cord-017161-lcqrd4v0	475	165	and	and	CC
cord-017161-lcqrd4v0	475	166	vascular	vascular	JJ
cord-017161-lcqrd4v0	475	167	cell	cell	NN
cord-017161-lcqrd4v0	475	168	adhesion	adhesion	NN
cord-017161-lcqrd4v0	475	169	molecule	molecule	NN
cord-017161-lcqrd4v0	475	170	1	1	CD
cord-017161-lcqrd4v0	475	171	in	in	IN
cord-017161-lcqrd4v0	475	172	human	human	JJ
cord-017161-lcqrd4v0	475	173	crescentic	crescentic	JJ
cord-017161-lcqrd4v0	475	174	glomerulonephritis	glomerulonephritis	NN
cord-017161-lcqrd4v0	475	175	Internalization	Internalization	NNP
cord-017161-lcqrd4v0	475	176	of	of	IN
cord-017161-lcqrd4v0	475	177	proteinase	proteinase	NN
cord-017161-lcqrd4v0	475	178	3	3	CD
cord-017161-lcqrd4v0	475	179	is	be	VBZ
cord-017161-lcqrd4v0	475	180	concomitant	concomitant	JJ
cord-017161-lcqrd4v0	475	181	with	with	IN
cord-017161-lcqrd4v0	475	182	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	475	183	cell	cell	NN
cord-017161-lcqrd4v0	475	184	apoptosis	apoptosis	NN
cord-017161-lcqrd4v0	475	185	and	and	CC
cord-017161-lcqrd4v0	475	186	internalization	internalization	NN
cord-017161-lcqrd4v0	475	187	of	of	IN
cord-017161-lcqrd4v0	475	188	myeloperoxidase	myeloperoxidase	NN
cord-017161-lcqrd4v0	475	189	with	with	IN
cord-017161-lcqrd4v0	475	190	generation	generation	NN
cord-017161-lcqrd4v0	475	191	of	of	IN
cord-017161-lcqrd4v0	475	192	intracellular	intracellular	JJ
cord-017161-lcqrd4v0	475	193	oxidants	oxidant	NNS
cord-017161-lcqrd4v0	475	194	Antineutrophil	Antineutrophil	NNP
cord-017161-lcqrd4v0	475	195	cytoplasmic	cytoplasmic	JJ
cord-017161-lcqrd4v0	475	196	antibodies	antibody	NNS
cord-017161-lcqrd4v0	475	197	induce	induce	VBP
cord-017161-lcqrd4v0	475	198	reactive	reactive	JJ
cord-017161-lcqrd4v0	475	199	oxygen	oxygen	NN
cord-017161-lcqrd4v0	475	200	-	-	HYPH
cord-017161-lcqrd4v0	475	201	dependent	dependent	JJ
cord-017161-lcqrd4v0	475	202	dysregulation	dysregulation	NN
cord-017161-lcqrd4v0	475	203	of	of	IN
cord-017161-lcqrd4v0	475	204	primed	primed	JJ
cord-017161-lcqrd4v0	475	205	neutrophil	neutrophil	NN
cord-017161-lcqrd4v0	475	206	apoptosis	apoptosis	NN
cord-017161-lcqrd4v0	475	207	and	and	CC
cord-017161-lcqrd4v0	475	208	clearance	clearance	NN
cord-017161-lcqrd4v0	475	209	by	by	IN
cord-017161-lcqrd4v0	475	210	macrophages	macrophage	NNS
cord-017161-lcqrd4v0	475	211	Neutrophil	Neutrophil	NNP
cord-017161-lcqrd4v0	475	212	priming	prime	VBG
cord-017161-lcqrd4v0	475	213	and	and	CC
cord-017161-lcqrd4v0	475	214	apoptosis	apoptosis	NN
cord-017161-lcqrd4v0	475	215	in	in	IN
cord-017161-lcqrd4v0	475	216	anti	anti	JJ
cord-017161-lcqrd4v0	475	217	-	-	JJ
cord-017161-lcqrd4v0	475	218	neutrophil	neutrophil	JJ
cord-017161-lcqrd4v0	475	219	cytoplasmic	cytoplasmic	JJ
cord-017161-lcqrd4v0	475	220	autoantibody	autoantibody	NN
cord-017161-lcqrd4v0	475	221	-	-	HYPH
cord-017161-lcqrd4v0	475	222	associated	associate	VBN
cord-017161-lcqrd4v0	475	223	vasculitis1	vasculitis1	NN
cord-017161-lcqrd4v0	475	224	Opsonization	opsonization	NN
cord-017161-lcqrd4v0	475	225	of	of	IN
cord-017161-lcqrd4v0	475	226	apoptotic	apoptotic	JJ
cord-017161-lcqrd4v0	475	227	neutrophils	neutrophil	NNS
cord-017161-lcqrd4v0	475	228	by	by	IN
cord-017161-lcqrd4v0	475	229	anti	anti	JJ
cord-017161-lcqrd4v0	475	230	neutrophil	neutrophil	JJ
cord-017161-lcqrd4v0	475	231	cytoplasmic	cytoplasmic	JJ
cord-017161-lcqrd4v0	475	232	antibodies	antibody	NNS
cord-017161-lcqrd4v0	475	233	(	(	-LRB-
cord-017161-lcqrd4v0	475	234	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	475	235	)	)	-RRB-
cord-017161-lcqrd4v0	475	236	leads	lead	VBZ
cord-017161-lcqrd4v0	475	237	to	to	IN
cord-017161-lcqrd4v0	475	238	enhanced	enhance	VBN
cord-017161-lcqrd4v0	475	239	uptake	uptake	NN
cord-017161-lcqrd4v0	475	240	by	by	IN
cord-017161-lcqrd4v0	475	241	macrophages	macrophage	NNS
cord-017161-lcqrd4v0	475	242	and	and	CC
cord-017161-lcqrd4v0	475	243	increased	increase	VBN
cord-017161-lcqrd4v0	475	244	release	release	NN
cord-017161-lcqrd4v0	475	245	of	of	IN
cord-017161-lcqrd4v0	475	246	tumour	tumour	NN
cord-017161-lcqrd4v0	475	247	necrosis	necrosis	NN
cord-017161-lcqrd4v0	475	248	factor	factor	NN
cord-017161-lcqrd4v0	475	249	alpha	alpha	NN
cord-017161-lcqrd4v0	475	250	(	(	-LRB-
cord-017161-lcqrd4v0	475	251	TNF	TNF	NNP
cord-017161-lcqrd4v0	475	252	a	a	DT
cord-017161-lcqrd4v0	475	253	)	)	-RRB-
cord-017161-lcqrd4v0	476	1	The	the	DT
cord-017161-lcqrd4v0	476	2	activation	activation	NN
cord-017161-lcqrd4v0	476	3	of	of	IN
cord-017161-lcqrd4v0	476	4	the	the	DT
cord-017161-lcqrd4v0	476	5	neutrophil	neutrophil	NN
cord-017161-lcqrd4v0	476	6	respiratory	respiratory	JJ
cord-017161-lcqrd4v0	476	7	burst	burst	NN
cord-017161-lcqrd4v0	476	8	by	by	IN
cord-017161-lcqrd4v0	476	9	antineutrophil	antineutrophil	NNP
cord-017161-lcqrd4v0	476	10	cytoplasm	cytoplasm	NNP
cord-017161-lcqrd4v0	476	11	autoantibody	autoantibody	NNP
cord-017161-lcqrd4v0	476	12	(	(	-LRB-
cord-017161-lcqrd4v0	476	13	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	476	14	)	)	-RRB-
cord-017161-lcqrd4v0	476	15	from	from	IN
cord-017161-lcqrd4v0	476	16	patients	patient	NNS
cord-017161-lcqrd4v0	476	17	with	with	IN
cord-017161-lcqrd4v0	476	18	systemic	systemic	JJ
cord-017161-lcqrd4v0	476	19	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	476	20	requires	require	VBZ
cord-017161-lcqrd4v0	476	21	tyrosine	tyrosine	NN
cord-017161-lcqrd4v0	476	22	kinases	kinase	NNS
cord-017161-lcqrd4v0	476	23	and	and	CC
cord-017161-lcqrd4v0	476	24	protein	protein	NN
cord-017161-lcqrd4v0	476	25	kinase	kinase	NN
cord-017161-lcqrd4v0	476	26	C	C	NNP
cord-017161-lcqrd4v0	476	27	activation	activation	NN
cord-017161-lcqrd4v0	476	28	Role	role	NN
cord-017161-lcqrd4v0	476	29	of	of	IN
cord-017161-lcqrd4v0	476	30	mitogen	mitogen	NN
cord-017161-lcqrd4v0	476	31	-	-	HYPH
cord-017161-lcqrd4v0	476	32	activated	activate	VBN
cord-017161-lcqrd4v0	476	33	protein	protein	NN
cord-017161-lcqrd4v0	476	34	kinases	kinase	NNS
cord-017161-lcqrd4v0	476	35	in	in	IN
cord-017161-lcqrd4v0	476	36	activation	activation	NN
cord-017161-lcqrd4v0	476	37	of	of	IN
cord-017161-lcqrd4v0	476	38	human	human	JJ
cord-017161-lcqrd4v0	476	39	neutrophils	neutrophil	NNS
cord-017161-lcqrd4v0	476	40	by	by	IN
cord-017161-lcqrd4v0	476	41	antineutrophil	antineutrophil	NNP
cord-017161-lcqrd4v0	476	42	cytoplasmic	cytoplasmic	JJ
cord-017161-lcqrd4v0	476	43	antibodies	antibody	NNS
cord-017161-lcqrd4v0	476	44	Pathology	Pathology	NNP
cord-017161-lcqrd4v0	476	45	of	of	IN
cord-017161-lcqrd4v0	476	46	pulmonary	pulmonary	JJ
cord-017161-lcqrd4v0	476	47	granulomatous	granulomatous	JJ
cord-017161-lcqrd4v0	476	48	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	476	49	.	.	.
cord-017161-lcqrd4v0	477	1	Sarcoidosis	sarcoidosis	NN
cord-017161-lcqrd4v0	477	2	,	,	,
cord-017161-lcqrd4v0	477	3	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	477	4	,	,	,
cord-017161-lcqrd4v0	477	5	and	and	CC
cord-017161-lcqrd4v0	477	6	diffuse	diffuse	VB
cord-017161-lcqrd4v0	477	7	lung	lung	NN
cord-017161-lcqrd4v0	477	8	diseases	disease	NNS
cord-017161-lcqrd4v0	477	9	T	T	NNP
cord-017161-lcqrd4v0	477	10	cell	cell	NN
cord-017161-lcqrd4v0	477	11	receptor	receptor	NN
cord-017161-lcqrd4v0	477	12	-	-	HYPH
cord-017161-lcqrd4v0	477	13	positive	positive	JJ
cord-017161-lcqrd4v0	477	14	cells	cell	NNS
cord-017161-lcqrd4v0	477	15	and	and	CC
cord-017161-lcqrd4v0	477	16	interferon-	interferon-	NN
cord-017161-lcqrd4v0	477	17	,	,	,
cord-017161-lcqrd4v0	477	18	but	but	CC
cord-017161-lcqrd4v0	477	19	not	not	RB
cord-017161-lcqrd4v0	477	20	inducible	inducible	JJ
cord-017161-lcqrd4v0	477	21	nitric	nitric	NN
cord-017161-lcqrd4v0	477	22	oxide	oxide	NN
cord-017161-lcqrd4v0	477	23	synthase	synthase	NN
cord-017161-lcqrd4v0	477	24	,	,	,
cord-017161-lcqrd4v0	477	25	are	be	VBP
cord-017161-lcqrd4v0	477	26	critical	critical	JJ
cord-017161-lcqrd4v0	477	27	for	for	IN
cord-017161-lcqrd4v0	477	28	granuloma	granuloma	NN
cord-017161-lcqrd4v0	477	29	necrosis	necrosis	NN
cord-017161-lcqrd4v0	477	30	in	in	IN
cord-017161-lcqrd4v0	477	31	a	a	DT
cord-017161-lcqrd4v0	477	32	mouse	mouse	NN
cord-017161-lcqrd4v0	477	33	model	model	NN
cord-017161-lcqrd4v0	477	34	of	of	IN
cord-017161-lcqrd4v0	477	35	mycobacteria	mycobacteria	NN
cord-017161-lcqrd4v0	477	36	-	-	HYPH
cord-017161-lcqrd4v0	477	37	induced	induce	VBN
cord-017161-lcqrd4v0	477	38	pulmonary	pulmonary	JJ
cord-017161-lcqrd4v0	477	39	immunopathology	immunopathology	NN
cord-017161-lcqrd4v0	477	40	Heterogeneity	heterogeneity	NN
cord-017161-lcqrd4v0	477	41	of	of	IN
cord-017161-lcqrd4v0	477	42	CD4	CD4	NNP
cord-017161-lcqrd4v0	477	43	+	+	CC
cord-017161-lcqrd4v0	477	44	and	and	CC
cord-017161-lcqrd4v0	477	45	CD8	CD8	NNP
cord-017161-lcqrd4v0	477	46	+	+	CC
cord-017161-lcqrd4v0	477	47	memory	memory	NN
cord-017161-lcqrd4v0	477	48	T	T	NNP
cord-017161-lcqrd4v0	477	49	cells	cell	NNS
cord-017161-lcqrd4v0	477	50	in	in	IN
cord-017161-lcqrd4v0	477	51	localized	localized	JJ
cord-017161-lcqrd4v0	477	52	and	and	CC
cord-017161-lcqrd4v0	477	53	generalized	generalize	VBN
cord-017161-lcqrd4v0	477	54	Wegener	Wegener	NNP
cord-017161-lcqrd4v0	477	55	's	's	POS
cord-017161-lcqrd4v0	477	56	granulomatosis	granulomatosis	NN
cord-017161-lcqrd4v0	477	57	CD28	CD28	NNP
cord-017161-lcqrd4v0	477	58	negative	negative	JJ
cord-017161-lcqrd4v0	477	59	T	t	NN
cord-017161-lcqrd4v0	477	60	cells	cell	NNS
cord-017161-lcqrd4v0	477	61	are	be	VBP
cord-017161-lcqrd4v0	477	62	enriched	enrich	VBN
cord-017161-lcqrd4v0	477	63	in	in	IN
cord-017161-lcqrd4v0	477	64	granulomatous	granulomatous	JJ
cord-017161-lcqrd4v0	477	65	lesions	lesion	NNS
cord-017161-lcqrd4v0	477	66	of	of	IN
cord-017161-lcqrd4v0	477	67	the	the	DT
cord-017161-lcqrd4v0	477	68	respiratory	respiratory	JJ
cord-017161-lcqrd4v0	477	69	tract	tract	NN
cord-017161-lcqrd4v0	477	70	in	in	IN
cord-017161-lcqrd4v0	477	71	Wegener	Wegener	NNP
cord-017161-lcqrd4v0	477	72	's	's	POS
cord-017161-lcqrd4v0	477	73	granulomatosis	granulomatosis	NN
cord-017161-lcqrd4v0	477	74	Differences	Differences	NNPS
cord-017161-lcqrd4v0	477	75	in	in	IN
cord-017161-lcqrd4v0	477	76	CCR5	CCR5	NNP
cord-017161-lcqrd4v0	477	77	expression	expression	NN
cord-017161-lcqrd4v0	477	78	on	on	IN
cord-017161-lcqrd4v0	477	79	peripheral	peripheral	JJ
cord-017161-lcqrd4v0	477	80	blood	blood	NN
cord-017161-lcqrd4v0	477	81	CD4	CD4	NNP
cord-017161-lcqrd4v0	477	82	+	+	CC
cord-017161-lcqrd4v0	477	83	CD28-T	cd28-t	NN
cord-017161-lcqrd4v0	477	84	-	-	HYPH
cord-017161-lcqrd4v0	477	85	cells	cell	NNS
cord-017161-lcqrd4v0	477	86	and	and	CC
cord-017161-lcqrd4v0	477	87	in	in	IN
cord-017161-lcqrd4v0	477	88	granulomatous	granulomatous	JJ
cord-017161-lcqrd4v0	477	89	lesions	lesion	NNS
cord-017161-lcqrd4v0	477	90	between	between	IN
cord-017161-lcqrd4v0	477	91	localized	localized	JJ
cord-017161-lcqrd4v0	477	92	and	and	CC
cord-017161-lcqrd4v0	477	93	generalized	generalize	VBN
cord-017161-lcqrd4v0	477	94	Wegener	Wegener	NNP
cord-017161-lcqrd4v0	477	95	's	's	POS
cord-017161-lcqrd4v0	477	96	granulomatosis	granulomatosis	NN
cord-017161-lcqrd4v0	477	97	Localized	Localized	NNP
cord-017161-lcqrd4v0	477	98	Wegeners	Wegeners	NNP
cord-017161-lcqrd4v0	477	99	granulomatosis	granulomatosis	NN
cord-017161-lcqrd4v0	477	100	:	:	:
cord-017161-lcqrd4v0	477	101	predominance	predominance	NN
cord-017161-lcqrd4v0	477	102	of	of	IN
cord-017161-lcqrd4v0	477	103	CD26	CD26	NNP
cord-017161-lcqrd4v0	477	104	and	and	CC
cord-017161-lcqrd4v0	477	105	IFN	IFN	NNP
cord-017161-lcqrd4v0	477	106	-	-	HYPH
cord-017161-lcqrd4v0	477	107	gamma	gamma	JJ
cord-017161-lcqrd4v0	477	108	expression	expression	NN
cord-017161-lcqrd4v0	477	109	Off	off	IN
cord-017161-lcqrd4v0	477	110	balance	balance	NN
cord-017161-lcqrd4v0	477	111	:	:	:
cord-017161-lcqrd4v0	477	112	T	t	NN
cord-017161-lcqrd4v0	477	113	cells	cell	NNS
cord-017161-lcqrd4v0	477	114	in	in	IN
cord-017161-lcqrd4v0	477	115	antineutrophil	antineutrophil	JJ
cord-017161-lcqrd4v0	477	116	cytoplasmic	cytoplasmic	JJ
cord-017161-lcqrd4v0	477	117	antibody	antibody	NN
cord-017161-lcqrd4v0	477	118	(	(	-LRB-
cord-017161-lcqrd4v0	477	119	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	477	120	)	)	-RRB-
cord-017161-lcqrd4v0	477	121	associated	associate	VBD
cord-017161-lcqrd4v0	477	122	vasculitides	vasculitide	NNS
cord-017161-lcqrd4v0	477	123	Th17	Th17	NNP
cord-017161-lcqrd4v0	478	1	cytokines	cytokine	NNS
cord-017161-lcqrd4v0	478	2	and	and	CC
cord-017161-lcqrd4v0	478	3	their	-PRON-	PRP$
cord-017161-lcqrd4v0	478	4	emerging	emerge	VBG
cord-017161-lcqrd4v0	478	5	roles	role	NNS
cord-017161-lcqrd4v0	478	6	in	in	IN
cord-017161-lcqrd4v0	478	7	in	in	IN
cord-017161-lcqrd4v0	478	8	fl	fl	NNP
cord-017161-lcqrd4v0	478	9	ammation	ammation	NN
cord-017161-lcqrd4v0	478	10	and	and	CC
cord-017161-lcqrd4v0	478	11	autoimmunity	autoimmunity	IN
cord-017161-lcqrd4v0	478	12	Skewed	skewed	JJ
cord-017161-lcqrd4v0	478	13	distribution	distribution	NN
cord-017161-lcqrd4v0	478	14	of	of	IN
cord-017161-lcqrd4v0	479	1	Th17	Th17	NNP
cord-017161-lcqrd4v0	480	1	lymphocytes	lymphocyte	NNS
cord-017161-lcqrd4v0	480	2	in	in	IN
cord-017161-lcqrd4v0	480	3	patients	patient	NNS
cord-017161-lcqrd4v0	480	4	with	with	IN
cord-017161-lcqrd4v0	480	5	Wegener	Wegener	NNP
cord-017161-lcqrd4v0	480	6	's	's	POS
cord-017161-lcqrd4v0	480	7	granulomatosis	granulomatosis	NN
cord-017161-lcqrd4v0	480	8	in	in	IN
cord-017161-lcqrd4v0	480	9	remission	remission	NN
cord-017161-lcqrd4v0	480	10	Functional	functional	JJ
cord-017161-lcqrd4v0	480	11	defect	defect	NN
cord-017161-lcqrd4v0	480	12	of	of	IN
cord-017161-lcqrd4v0	480	13	circulating	circulate	VBG
cord-017161-lcqrd4v0	480	14	regulatory	regulatory	JJ
cord-017161-lcqrd4v0	480	15	CD4	CD4	NNP
cord-017161-lcqrd4v0	480	16	+	+	CC
cord-017161-lcqrd4v0	480	17	T	t	NN
cord-017161-lcqrd4v0	480	18	cells	cell	NNS
cord-017161-lcqrd4v0	480	19	in	in	IN
cord-017161-lcqrd4v0	480	20	patients	patient	NNS
cord-017161-lcqrd4v0	480	21	with	with	IN
cord-017161-lcqrd4v0	480	22	Wegener	Wegener	NNP
cord-017161-lcqrd4v0	480	23	's	's	POS
cord-017161-lcqrd4v0	480	24	granulomatosis	granulomatosis	NN
cord-017161-lcqrd4v0	480	25	in	in	IN
cord-017161-lcqrd4v0	480	26	remission	remission	NN
cord-017161-lcqrd4v0	481	1	Antineutrophil	Antineutrophil	NNP
cord-017161-lcqrd4v0	481	2	cytoplasmic	cytoplasmic	JJ
cord-017161-lcqrd4v0	481	3	autoantibodies	autoantibody	NNS
cord-017161-lcqrd4v0	481	4	speci	speci	NNS
cord-017161-lcqrd4v0	481	5	fi	fi	NN
cord-017161-lcqrd4v0	481	6	c	c	NN
cord-017161-lcqrd4v0	481	7	for	for	IN
cord-017161-lcqrd4v0	481	8	myeloperoxidase	myeloperoxidase	NNP
cord-017161-lcqrd4v0	481	9	cause	cause	VBP
cord-017161-lcqrd4v0	481	10	glomerulonephritis	glomerulonephritis	NN
cord-017161-lcqrd4v0	481	11	and	and	CC
cord-017161-lcqrd4v0	481	12	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	481	13	in	in	IN
cord-017161-lcqrd4v0	481	14	mice	mice	NN
cord-017161-lcqrd4v0	481	15	Alternative	alternative	JJ
cord-017161-lcqrd4v0	481	16	complement	complement	NN
cord-017161-lcqrd4v0	481	17	pathway	pathway	NN
cord-017161-lcqrd4v0	481	18	in	in	IN
cord-017161-lcqrd4v0	481	19	the	the	DT
cord-017161-lcqrd4v0	481	20	pathogenesis	pathogenesis	NN
cord-017161-lcqrd4v0	481	21	of	of	IN
cord-017161-lcqrd4v0	481	22	disease	disease	NN
cord-017161-lcqrd4v0	481	23	mediated	mediate	VBN
cord-017161-lcqrd4v0	481	24	by	by	IN
cord-017161-lcqrd4v0	481	25	anti	anti	JJ
cord-017161-lcqrd4v0	481	26	-	-	JJ
cord-017161-lcqrd4v0	481	27	neutrophil	neutrophil	JJ
cord-017161-lcqrd4v0	481	28	cytoplasmic	cytoplasmic	JJ
cord-017161-lcqrd4v0	481	29	autoantibodies	autoantibody	NNS
cord-017161-lcqrd4v0	481	30	Antineutrophil	Antineutrophil	NNP
cord-017161-lcqrd4v0	481	31	cytoplasm	cytoplasm	IN
cord-017161-lcqrd4v0	481	32	antibodies	antibody	NNS
cord-017161-lcqrd4v0	481	33	directed	direct	VBN
cord-017161-lcqrd4v0	481	34	against	against	IN
cord-017161-lcqrd4v0	481	35	myeloperoxidase	myeloperoxidase	NNP
cord-017161-lcqrd4v0	481	36	augment	augment	VB
cord-017161-lcqrd4v0	481	37	leukocyte	leukocyte	NN
cord-017161-lcqrd4v0	481	38	-	-	HYPH
cord-017161-lcqrd4v0	481	39	microvascular	microvascular	JJ
cord-017161-lcqrd4v0	481	40	interactions	interaction	NNS
cord-017161-lcqrd4v0	481	41	in	in	IN
cord-017161-lcqrd4v0	481	42	vivo	vivo	NNP
cord-017161-lcqrd4v0	481	43	Relapses	Relapses	NNP
cord-017161-lcqrd4v0	481	44	in	in	IN
cord-017161-lcqrd4v0	481	45	Wegener	Wegener	NNP
cord-017161-lcqrd4v0	481	46	's	's	POS
cord-017161-lcqrd4v0	481	47	granulomatosis	granulomatosis	NN
cord-017161-lcqrd4v0	481	48	:	:	:
cord-017161-lcqrd4v0	481	49	the	the	DT
cord-017161-lcqrd4v0	481	50	role	role	NN
cord-017161-lcqrd4v0	481	51	of	of	IN
cord-017161-lcqrd4v0	481	52	infection	infection	NN
cord-017161-lcqrd4v0	482	1	The	the	DT
cord-017161-lcqrd4v0	482	2	treatment	treatment	NN
cord-017161-lcqrd4v0	482	3	of	of	IN
cord-017161-lcqrd4v0	482	4	Wegener	Wegener	NNP
cord-017161-lcqrd4v0	482	5	's	's	POS
cord-017161-lcqrd4v0	482	6	granulomatosis	granulomatosis	NN
cord-017161-lcqrd4v0	482	7	with	with	IN
cord-017161-lcqrd4v0	482	8	trimethoprim	trimethoprim	NNP
cord-017161-lcqrd4v0	482	9	/	/	SYM
cord-017161-lcqrd4v0	482	10	sulfamethoxazole	sulfamethoxazole	NN
cord-017161-lcqrd4v0	482	11	:	:	:
cord-017161-lcqrd4v0	482	12	illusion	illusion	NN
cord-017161-lcqrd4v0	482	13	or	or	CC
cord-017161-lcqrd4v0	482	14	vision	vision	NN
cord-017161-lcqrd4v0	482	15	?	?	.
cord-017161-lcqrd4v0	483	1	Trimethoprimsulfamethoxazole	Trimethoprimsulfamethoxazole	NNP
cord-017161-lcqrd4v0	483	2	(	(	-LRB-
cord-017161-lcqrd4v0	483	3	co	co	JJ
cord-017161-lcqrd4v0	483	4	-	-	JJ
cord-017161-lcqrd4v0	483	5	trimoxazole	trimoxazole	NN
cord-017161-lcqrd4v0	483	6	)	)	-RRB-
cord-017161-lcqrd4v0	483	7	for	for	IN
cord-017161-lcqrd4v0	483	8	the	the	DT
cord-017161-lcqrd4v0	483	9	prevention	prevention	NN
cord-017161-lcqrd4v0	483	10	of	of	IN
cord-017161-lcqrd4v0	483	11	relapses	relapse	NNS
cord-017161-lcqrd4v0	483	12	of	of	IN
cord-017161-lcqrd4v0	483	13	Wegener	Wegener	NNP
cord-017161-lcqrd4v0	483	14	's	's	POS
cord-017161-lcqrd4v0	483	15	granulomatosis	granulomatosis	NN
cord-017161-lcqrd4v0	484	1	The	the	DT
cord-017161-lcqrd4v0	484	2	relation	relation	NN
cord-017161-lcqrd4v0	484	3	between	between	IN
cord-017161-lcqrd4v0	484	4	Staphylococcus	Staphylococcus	NNP
cord-017161-lcqrd4v0	484	5	aureus	aureus	NNP
cord-017161-lcqrd4v0	484	6	and	and	CC
cord-017161-lcqrd4v0	484	7	Wegener	Wegener	NNP
cord-017161-lcqrd4v0	484	8	's	's	POS
cord-017161-lcqrd4v0	484	9	granulomatosis	granulomatosis	NN
cord-017161-lcqrd4v0	484	10	:	:	:
cord-017161-lcqrd4v0	484	11	current	current	JJ
cord-017161-lcqrd4v0	484	12	knowledge	knowledge	NN
cord-017161-lcqrd4v0	484	13	and	and	CC
cord-017161-lcqrd4v0	484	14	future	future	JJ
cord-017161-lcqrd4v0	484	15	directions	direction	NNS
cord-017161-lcqrd4v0	485	1	Autoimmunity	Autoimmunity	NNP
cord-017161-lcqrd4v0	485	2	is	be	VBZ
cord-017161-lcqrd4v0	485	3	triggered	trigger	VBN
cord-017161-lcqrd4v0	485	4	by	by	IN
cord-017161-lcqrd4v0	485	5	cPR-3	cPR-3	NNP
cord-017161-lcqrd4v0	485	6	(	(	-LRB-
cord-017161-lcqrd4v0	485	7	105	105	CD
cord-017161-lcqrd4v0	485	8	-	-	SYM
cord-017161-lcqrd4v0	485	9	201	201	CD
cord-017161-lcqrd4v0	485	10	)	)	-RRB-
cord-017161-lcqrd4v0	485	11	,	,	,
cord-017161-lcqrd4v0	485	12	a	a	DT
cord-017161-lcqrd4v0	485	13	protein	protein	NN
cord-017161-lcqrd4v0	485	14	complementary	complementary	JJ
cord-017161-lcqrd4v0	485	15	to	to	IN
cord-017161-lcqrd4v0	485	16	human	human	JJ
cord-017161-lcqrd4v0	485	17	autoantigen	autoantigen	NN
cord-017161-lcqrd4v0	485	18	proteinase-3	proteinase-3	NNP
cord-017161-lcqrd4v0	485	19	Molecular	Molecular	NNP
cord-017161-lcqrd4v0	485	20	mimicry	mimicry	NN
cord-017161-lcqrd4v0	485	21	in	in	IN
cord-017161-lcqrd4v0	485	22	pauci	pauci	NN
cord-017161-lcqrd4v0	485	23	-	-	HYPH
cord-017161-lcqrd4v0	485	24	immune	immune	JJ
cord-017161-lcqrd4v0	485	25	focal	focal	JJ
cord-017161-lcqrd4v0	485	26	necrotizing	necrotize	VBG
cord-017161-lcqrd4v0	485	27	glomerulonephritis	glomerulonephritis	NN
cord-017161-lcqrd4v0	486	1	The	the	DT
cord-017161-lcqrd4v0	486	2	contribution	contribution	NN
cord-017161-lcqrd4v0	486	3	of	of	IN
cord-017161-lcqrd4v0	486	4	genetic	genetic	JJ
cord-017161-lcqrd4v0	486	5	variation	variation	NN
cord-017161-lcqrd4v0	486	6	and	and	CC
cord-017161-lcqrd4v0	486	7	infection	infection	NN
cord-017161-lcqrd4v0	486	8	to	to	IN
cord-017161-lcqrd4v0	486	9	the	the	DT
cord-017161-lcqrd4v0	486	10	pathogenesis	pathogenesis	NN
cord-017161-lcqrd4v0	486	11	of	of	IN
cord-017161-lcqrd4v0	486	12	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	486	13	-	-	HYPH
cord-017161-lcqrd4v0	486	14	associated	associate	VBN
cord-017161-lcqrd4v0	486	15	systemic	systemic	JJ
cord-017161-lcqrd4v0	486	16	vasculitis	vasculitis	JJ
cord-017161-lcqrd4v0	486	17	New	new	JJ
cord-017161-lcqrd4v0	486	18	genomic	genomic	JJ
cord-017161-lcqrd4v0	486	19	region	region	NN
cord-017161-lcqrd4v0	486	20	for	for	IN
cord-017161-lcqrd4v0	486	21	Wegener	Wegener	NNP
cord-017161-lcqrd4v0	486	22	's	's	POS
cord-017161-lcqrd4v0	486	23	granulomatosis	granulomatosis	NN
cord-017161-lcqrd4v0	486	24	as	as	IN
cord-017161-lcqrd4v0	486	25	revealed	reveal	VBN
cord-017161-lcqrd4v0	486	26	by	by	IN
cord-017161-lcqrd4v0	486	27	an	an	DT
cord-017161-lcqrd4v0	486	28	extended	extended	JJ
cord-017161-lcqrd4v0	486	29	association	association	NN
cord-017161-lcqrd4v0	486	30	screen	screen	NN
cord-017161-lcqrd4v0	486	31	with	with	IN
cord-017161-lcqrd4v0	486	32	202	202	CD
cord-017161-lcqrd4v0	486	33	apoptosis	apoptosis	NN
cord-017161-lcqrd4v0	486	34	-	-	HYPH
cord-017161-lcqrd4v0	486	35	related	relate	VBN
cord-017161-lcqrd4v0	486	36	genes	gene	NNS
cord-017161-lcqrd4v0	487	1	The	the	DT
cord-017161-lcqrd4v0	487	2	Wegener	Wegener	NNP
cord-017161-lcqrd4v0	487	3	's	's	POS
cord-017161-lcqrd4v0	487	4	granulomatosis	granulomatosis	NN
cord-017161-lcqrd4v0	487	5	quantitative	quantitative	JJ
cord-017161-lcqrd4v0	487	6	trait	trait	NN
cord-017161-lcqrd4v0	487	7	locus	locus	NN
cord-017161-lcqrd4v0	487	8	on	on	IN
cord-017161-lcqrd4v0	487	9	chromosome	chromosome	NN
cord-017161-lcqrd4v0	487	10	6p21.3	6p21.3	CD
cord-017161-lcqrd4v0	488	1	as	as	IN
cord-017161-lcqrd4v0	488	2	characterised	characterise	VBN
cord-017161-lcqrd4v0	488	3	by	by	IN
cord-017161-lcqrd4v0	488	4	tagSNP	tagSNP	NNP
cord-017161-lcqrd4v0	488	5	genotyping	genotyping	NN
cord-017161-lcqrd4v0	488	6	HLA	HLA	NNP
cord-017161-lcqrd4v0	488	7	typing	type	VBG
cord-017161-lcqrd4v0	488	8	in	in	IN
cord-017161-lcqrd4v0	488	9	patients	patient	NNS
cord-017161-lcqrd4v0	488	10	with	with	IN
cord-017161-lcqrd4v0	488	11	Wegener	Wegener	NNP
cord-017161-lcqrd4v0	488	12	granulomatosis	granulomatosis	NN
cord-017161-lcqrd4v0	488	13	HLA	HLA	NNP
cord-017161-lcqrd4v0	488	14	class	class	NN
cord-017161-lcqrd4v0	488	15	II	ii	NN
cord-017161-lcqrd4v0	488	16	speci	speci	NNS
cord-017161-lcqrd4v0	488	17	fi	fi	NN
cord-017161-lcqrd4v0	488	18	cities	city	NNS
cord-017161-lcqrd4v0	488	19	in	in	IN
cord-017161-lcqrd4v0	488	20	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	488	21	with	with	IN
cord-017161-lcqrd4v0	488	22	antibodies	antibody	NNS
cord-017161-lcqrd4v0	488	23	to	to	TO
cord-017161-lcqrd4v0	488	24	neutrophil	neutrophil	VB
cord-017161-lcqrd4v0	488	25	cytoplasmic	cytoplasmic	JJ
cord-017161-lcqrd4v0	488	26	antigens	antigen	NNS
cord-017161-lcqrd4v0	488	27	Association	Association	NNP
cord-017161-lcqrd4v0	488	28	of	of	IN
cord-017161-lcqrd4v0	488	29	Wegener	Wegener	NNP
cord-017161-lcqrd4v0	488	30	's	's	POS
cord-017161-lcqrd4v0	488	31	granulomatosis	granulomatosis	NN
cord-017161-lcqrd4v0	488	32	with	with	IN
cord-017161-lcqrd4v0	488	33	HLA	HLA	NNP
cord-017161-lcqrd4v0	488	34	antigens	antigen	NNS
cord-017161-lcqrd4v0	488	35	and	and	CC
cord-017161-lcqrd4v0	488	36	other	other	JJ
cord-017161-lcqrd4v0	488	37	genetic	genetic	JJ
cord-017161-lcqrd4v0	488	38	markers	marker	NNS
cord-017161-lcqrd4v0	488	39	HLA	HLA	NNP
cord-017161-lcqrd4v0	488	40	-	-	HYPH
cord-017161-lcqrd4v0	488	41	DR4	dr4	NN
cord-017161-lcqrd4v0	488	42	,	,	,
cord-017161-lcqrd4v0	488	43	DR13	DR13	NNP
cord-017161-lcqrd4v0	488	44	(	(	-LRB-
cord-017161-lcqrd4v0	488	45	6	6	CD
cord-017161-lcqrd4v0	488	46	)	)	-RRB-
cord-017161-lcqrd4v0	488	47	and	and	CC
cord-017161-lcqrd4v0	488	48	the	the	DT
cord-017161-lcqrd4v0	488	49	ancestral	ancestral	JJ
cord-017161-lcqrd4v0	488	50	haplotype	haplotype	NN
cord-017161-lcqrd4v0	488	51	A1B8DR3	A1B8DR3	NNS
cord-017161-lcqrd4v0	488	52	are	be	VBP
cord-017161-lcqrd4v0	488	53	associated	associate	VBN
cord-017161-lcqrd4v0	488	54	with	with	IN
cord-017161-lcqrd4v0	488	55	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	488	56	-	-	HYPH
cord-017161-lcqrd4v0	488	57	associated	associate	VBN
cord-017161-lcqrd4v0	488	58	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	488	59	HLA	HLA	NNP
cord-017161-lcqrd4v0	488	60	-	-	HYPH
cord-017161-lcqrd4v0	488	61	DRB4	DRB4	NNP
cord-017161-lcqrd4v0	488	62	as	as	IN
cord-017161-lcqrd4v0	488	63	a	a	DT
cord-017161-lcqrd4v0	488	64	genetic	genetic	JJ
cord-017161-lcqrd4v0	488	65	risk	risk	NN
cord-017161-lcqrd4v0	488	66	factor	factor	NN
cord-017161-lcqrd4v0	488	67	for	for	IN
cord-017161-lcqrd4v0	488	68	Churg	Churg	NNP
cord-017161-lcqrd4v0	488	69	Strauss	Strauss	NNP
cord-017161-lcqrd4v0	488	70	syndrome	syndrome	NN
cord-017161-lcqrd4v0	488	71	Associations	Associations	NNPS
cord-017161-lcqrd4v0	488	72	of	of	IN
cord-017161-lcqrd4v0	488	73	Churg	Churg	NNP
cord-017161-lcqrd4v0	488	74	Strauss	Strauss	NNP
cord-017161-lcqrd4v0	488	75	syndrome	syndrome	NN
cord-017161-lcqrd4v0	488	76	with	with	IN
cord-017161-lcqrd4v0	488	77	the	the	DT
cord-017161-lcqrd4v0	488	78	HLA	HLA	NNP
cord-017161-lcqrd4v0	488	79	-	-	HYPH
cord-017161-lcqrd4v0	488	80	DRB1	DRB1	NNP
cord-017161-lcqrd4v0	488	81	locus	locus	NN
cord-017161-lcqrd4v0	488	82	,	,	,
cord-017161-lcqrd4v0	488	83	and	and	CC
cord-017161-lcqrd4v0	488	84	relationship	relationship	NN
cord-017161-lcqrd4v0	488	85	to	to	IN
cord-017161-lcqrd4v0	488	86	the	the	DT
cord-017161-lcqrd4v0	488	87	genetics	genetic	NNS
cord-017161-lcqrd4v0	488	88	of	of	IN
cord-017161-lcqrd4v0	488	89	antineutrophil	antineutrophil	NNP
cord-017161-lcqrd4v0	488	90	cytoplasmic	cytoplasmic	JJ
cord-017161-lcqrd4v0	488	91	antibody	antibody	NN
cord-017161-lcqrd4v0	488	92	-	-	HYPH
cord-017161-lcqrd4v0	488	93	associated	associate	VBN
cord-017161-lcqrd4v0	488	94	vasculitides	vasculitide	NNS
cord-017161-lcqrd4v0	488	95	:	:	:
cord-017161-lcqrd4v0	488	96	comment	comment	VB
cord-017161-lcqrd4v0	488	97	on	on	IN
cord-017161-lcqrd4v0	488	98	the	the	DT
cord-017161-lcqrd4v0	488	99	article	article	NN
cord-017161-lcqrd4v0	488	100	by	by	IN
cord-017161-lcqrd4v0	488	101	Vaglio	Vaglio	NNP
cord-017161-lcqrd4v0	488	102	et	et	NNP
cord-017161-lcqrd4v0	488	103	al	al	NNP
cord-017161-lcqrd4v0	489	1	The	the	DT
cord-017161-lcqrd4v0	489	2	PTPN22	ptpn22	CD
cord-017161-lcqrd4v0	489	3	620W	620W	NNP
cord-017161-lcqrd4v0	489	4	allele	allele	NN
cord-017161-lcqrd4v0	489	5	is	be	VBZ
cord-017161-lcqrd4v0	489	6	a	a	DT
cord-017161-lcqrd4v0	489	7	risk	risk	NN
cord-017161-lcqrd4v0	489	8	factor	factor	NN
cord-017161-lcqrd4v0	489	9	for	for	IN
cord-017161-lcqrd4v0	489	10	Wegener	Wegener	NNP
cord-017161-lcqrd4v0	489	11	's	's	POS
cord-017161-lcqrd4v0	489	12	granulomatosis	granulomatosis	NN
cord-017161-lcqrd4v0	489	13	Con	con	NN
cord-017161-lcqrd4v0	489	14	fi	fi	NN
cord-017161-lcqrd4v0	489	15	rmation	rmation	NN
cord-017161-lcqrd4v0	489	16	of	of	IN
cord-017161-lcqrd4v0	489	17	the	the	DT
cord-017161-lcqrd4v0	489	18	genetic	genetic	JJ
cord-017161-lcqrd4v0	489	19	association	association	NN
cord-017161-lcqrd4v0	489	20	of	of	IN
cord-017161-lcqrd4v0	489	21	CTLA	CTLA	NNP
cord-017161-lcqrd4v0	489	22	4	4	CD
cord-017161-lcqrd4v0	489	23	and	and	CC
cord-017161-lcqrd4v0	489	24	PTPN	PTPN	NNP
cord-017161-lcqrd4v0	489	25	22	22	CD
cord-017161-lcqrd4v0	489	26	with	with	IN
cord-017161-lcqrd4v0	489	27	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	489	28	-	-	HYPH
cord-017161-lcqrd4v0	489	29	associated	associate	VBN
cord-017161-lcqrd4v0	489	30	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	489	31	Contrasting	contrast	VBG
cord-017161-lcqrd4v0	489	32	genetic	genetic	JJ
cord-017161-lcqrd4v0	489	33	association	association	NN
cord-017161-lcqrd4v0	489	34	of	of	IN
cord-017161-lcqrd4v0	489	35	IL	IL	NNP
cord-017161-lcqrd4v0	489	36	2	2	CD
cord-017161-lcqrd4v0	489	37	RA	RA	NNP
cord-017161-lcqrd4v0	489	38	with	with	IN
cord-017161-lcqrd4v0	489	39	SLE	SLE	NNP
cord-017161-lcqrd4v0	489	40	and	and	CC
cord-017161-lcqrd4v0	489	41	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	489	42	-	-	HYPH
cord-017161-lcqrd4v0	489	43	associated	associate	VBN
cord-017161-lcqrd4v0	489	44	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	489	45	Coding	code	VBG
cord-017161-lcqrd4v0	489	46	sequence	sequence	NN
cord-017161-lcqrd4v0	489	47	1	1	CD
cord-017161-lcqrd4v0	489	48	and	and	CC
cord-017161-lcqrd4v0	489	49	promoter	promoter	NN
cord-017161-lcqrd4v0	489	50	single	single	JJ
cord-017161-lcqrd4v0	489	51	nucleotide	nucleotide	JJ
cord-017161-lcqrd4v0	489	52	polymorphisms	polymorphism	NNS
cord-017161-lcqrd4v0	489	53	in	in	IN
cord-017161-lcqrd4v0	489	54	the	the	DT
cord-017161-lcqrd4v0	489	55	CTLA-4	CTLA-4	NNP
cord-017161-lcqrd4v0	489	56	gene	gene	NN
cord-017161-lcqrd4v0	489	57	in	in	IN
cord-017161-lcqrd4v0	489	58	Wegener	Wegener	NNP
cord-017161-lcqrd4v0	489	59	's	's	POS
cord-017161-lcqrd4v0	489	60	granulomatosis	granulomatosis	NN
cord-017161-lcqrd4v0	489	61	Immunoregulatory	Immunoregulatory	NNP
cord-017161-lcqrd4v0	489	62	gene	gene	NN
cord-017161-lcqrd4v0	489	63	polymorphisms	polymorphism	NNS
cord-017161-lcqrd4v0	489	64	are	be	VBP
cord-017161-lcqrd4v0	489	65	associated	associate	VBN
cord-017161-lcqrd4v0	489	66	with	with	IN
cord-017161-lcqrd4v0	489	67	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	489	68	-	-	HYPH
cord-017161-lcqrd4v0	489	69	related	relate	VBN
cord-017161-lcqrd4v0	489	70	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	489	71	Proteinase	Proteinase	NNP
cord-017161-lcqrd4v0	489	72	3	3	CD
cord-017161-lcqrd4v0	489	73	gene	gene	NN
cord-017161-lcqrd4v0	489	74	polymorphisms	polymorphism	NNS
cord-017161-lcqrd4v0	489	75	and	and	CC
cord-017161-lcqrd4v0	489	76	Wegener	Wegener	NNP
cord-017161-lcqrd4v0	489	77	's	's	POS
cord-017161-lcqrd4v0	489	78	granulomatosis	granulomatosis	NN
cord-017161-lcqrd4v0	489	79	Antitrypsin	Antitrypsin	NNP
cord-017161-lcqrd4v0	489	80	(	(	-LRB-
cord-017161-lcqrd4v0	489	81	AAT	AAT	NNP
cord-017161-lcqrd4v0	489	82	)	)	-RRB-
cord-017161-lcqrd4v0	489	83	de	de	NN
cord-017161-lcqrd4v0	489	84	fi	fi	FW
cord-017161-lcqrd4v0	489	85	ciency	ciency	NN
cord-017161-lcqrd4v0	489	86	and	and	CC
cord-017161-lcqrd4v0	489	87	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	489	88	positive	positive	JJ
cord-017161-lcqrd4v0	489	89	systemic	systemic	JJ
cord-017161-lcqrd4v0	489	90	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	489	91	:	:	:
cord-017161-lcqrd4v0	489	92	genetic	genetic	JJ
cord-017161-lcqrd4v0	489	93	and	and	CC
cord-017161-lcqrd4v0	489	94	clinical	clinical	JJ
cord-017161-lcqrd4v0	489	95	implications	implication	NNS
cord-017161-lcqrd4v0	489	96	Alpha	alpha	NN
cord-017161-lcqrd4v0	489	97	1-antitrypsin	1-antitrypsin	CD
cord-017161-lcqrd4v0	489	98	phenotypes	phenotype	NNS
cord-017161-lcqrd4v0	489	99	in	in	IN
cord-017161-lcqrd4v0	489	100	patients	patient	NNS
cord-017161-lcqrd4v0	489	101	with	with	IN
cord-017161-lcqrd4v0	489	102	anti	anti	JJ
cord-017161-lcqrd4v0	489	103	-	-	JJ
cord-017161-lcqrd4v0	489	104	neutrophil	neutrophil	JJ
cord-017161-lcqrd4v0	489	105	cytoplasmic	cytoplasmic	JJ
cord-017161-lcqrd4v0	489	106	antibody	antibody	NN
cord-017161-lcqrd4v0	489	107	-	-	HYPH
cord-017161-lcqrd4v0	489	108	positive	positive	JJ
cord-017161-lcqrd4v0	489	109	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	490	1	A	a	DT
cord-017161-lcqrd4v0	490	2	linkage	linkage	NN
cord-017161-lcqrd4v0	490	3	disequilibrium	disequilibrium	NN
cord-017161-lcqrd4v0	490	4	between	between	IN
cord-017161-lcqrd4v0	490	5	genes	gene	NNS
cord-017161-lcqrd4v0	490	6	at	at	IN
cord-017161-lcqrd4v0	490	7	the	the	DT
cord-017161-lcqrd4v0	490	8	serine	serine	JJ
cord-017161-lcqrd4v0	490	9	protease	protease	NN
cord-017161-lcqrd4v0	490	10	inhibitor	inhibitor	NN
cord-017161-lcqrd4v0	490	11	gene	gene	NN
cord-017161-lcqrd4v0	490	12	cluster	cluster	NN
cord-017161-lcqrd4v0	490	13	on	on	IN
cord-017161-lcqrd4v0	490	14	chromosome	chromosome	NN
cord-017161-lcqrd4v0	490	15	14q32.1	14q32.1	CD
cord-017161-lcqrd4v0	490	16	is	be	VBZ
cord-017161-lcqrd4v0	490	17	associated	associate	VBN
cord-017161-lcqrd4v0	490	18	with	with	IN
cord-017161-lcqrd4v0	490	19	Wegener	Wegener	NNP
cord-017161-lcqrd4v0	490	20	's	's	POS
cord-017161-lcqrd4v0	490	21	granulomatosis	granulomatosis	NN
cord-017161-lcqrd4v0	490	22	Strong	strong	JJ
cord-017161-lcqrd4v0	490	23	link	link	NN
cord-017161-lcqrd4v0	490	24	between	between	IN
cord-017161-lcqrd4v0	490	25	the	the	DT
cord-017161-lcqrd4v0	490	26	alpha1	alpha1	NN
cord-017161-lcqrd4v0	490	27	antitrypsin	antitrypsin	NN
cord-017161-lcqrd4v0	490	28	PiZ	piz	NN
cord-017161-lcqrd4v0	490	29	allele	allele	NN
cord-017161-lcqrd4v0	490	30	and	and	CC
cord-017161-lcqrd4v0	490	31	Wegener	Wegener	NNP
cord-017161-lcqrd4v0	490	32	's	's	POS
cord-017161-lcqrd4v0	490	33	granulomatosis	granulomatosis	NN
cord-017161-lcqrd4v0	490	34	Complexes	complex	NNS
cord-017161-lcqrd4v0	490	35	between	between	IN
cord-017161-lcqrd4v0	490	36	proteinase	proteinase	NN
cord-017161-lcqrd4v0	490	37	3	3	CD
cord-017161-lcqrd4v0	490	38	,	,	,
cord-017161-lcqrd4v0	490	39	alpha	alpha	NN
cord-017161-lcqrd4v0	490	40	1-antitrypsin	1-antitrypsin	CD
cord-017161-lcqrd4v0	490	41	and	and	CC
cord-017161-lcqrd4v0	490	42	proteinase	proteinase	NN
cord-017161-lcqrd4v0	490	43	3	3	CD
cord-017161-lcqrd4v0	490	44	anti	anti	JJ
cord-017161-lcqrd4v0	490	45	-	-	JJ
cord-017161-lcqrd4v0	490	46	neutrophil	neutrophil	JJ
cord-017161-lcqrd4v0	490	47	cytoplasm	cytoplasm	JJ
cord-017161-lcqrd4v0	490	48	autoantibodies	autoantibody	NNS
cord-017161-lcqrd4v0	490	49	:	:	:
cord-017161-lcqrd4v0	490	50	a	a	DT
cord-017161-lcqrd4v0	490	51	comparison	comparison	NN
cord-017161-lcqrd4v0	490	52	between	between	IN
cord-017161-lcqrd4v0	490	53	1	1	CD
cord-017161-lcqrd4v0	490	54	antitrypsin	antitrypsin	NN
cord-017161-lcqrd4v0	490	55	PiZ	piz	NN
cord-017161-lcqrd4v0	490	56	allele	allele	NN
cord-017161-lcqrd4v0	490	57	carriers	carrier	NNS
cord-017161-lcqrd4v0	490	58	and	and	CC
cord-017161-lcqrd4v0	490	59	non	non	NNS
cord-017161-lcqrd4v0	490	60	-	-	NNS
cord-017161-lcqrd4v0	490	61	carriers	carrier	NNS
cord-017161-lcqrd4v0	490	62	with	with	IN
cord-017161-lcqrd4v0	490	63	Wegener	Wegener	NNP
cord-017161-lcqrd4v0	490	64	's	's	POS
cord-017161-lcqrd4v0	490	65	granulomatosis	granulomatosis	NN
cord-017161-lcqrd4v0	490	66	C3	C3	NNP
cord-017161-lcqrd4v0	490	67	and	and	CC
cord-017161-lcqrd4v0	490	68	C4	C4	NNP
cord-017161-lcqrd4v0	490	69	allotypes	allotype	NNS
cord-017161-lcqrd4v0	490	70	in	in	IN
cord-017161-lcqrd4v0	490	71	anti	anti	JJ
cord-017161-lcqrd4v0	490	72	-	-	JJ
cord-017161-lcqrd4v0	490	73	neutrophil	neutrophil	JJ
cord-017161-lcqrd4v0	490	74	cytoplasmic	cytoplasmic	JJ
cord-017161-lcqrd4v0	490	75	autoantibody	autoantibody	NN
cord-017161-lcqrd4v0	490	76	(	(	-LRB-
cord-017161-lcqrd4v0	490	77	ANCA)-positive	anca)-positive	IN
cord-017161-lcqrd4v0	490	78	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	490	79	The	the	DT
cord-017161-lcqrd4v0	490	80	association	association	NN
cord-017161-lcqrd4v0	490	81	of	of	IN
cord-017161-lcqrd4v0	490	82	CD18	CD18	NNP
cord-017161-lcqrd4v0	490	83	alleles	allele	NNS
cord-017161-lcqrd4v0	490	84	with	with	IN
cord-017161-lcqrd4v0	490	85	anti	anti	JJ
cord-017161-lcqrd4v0	490	86	-	-	JJ
cord-017161-lcqrd4v0	490	87	myeloperoxidase	myeloperoxidase	JJ
cord-017161-lcqrd4v0	490	88	subtypes	subtype	NNS
cord-017161-lcqrd4v0	490	89	of	of	IN
cord-017161-lcqrd4v0	490	90	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	490	91	-	-	HYPH
cord-017161-lcqrd4v0	490	92	associated	associate	VBN
cord-017161-lcqrd4v0	490	93	systemic	systemic	JJ
cord-017161-lcqrd4v0	490	94	vasculitides	vasculitide	NNS
cord-017161-lcqrd4v0	490	95	Novel	Novel	NNP
cord-017161-lcqrd4v0	490	96	genetic	genetic	JJ
cord-017161-lcqrd4v0	490	97	association	association	NN
cord-017161-lcqrd4v0	490	98	of	of	IN
cord-017161-lcqrd4v0	490	99	Wegener	Wegener	NNP
cord-017161-lcqrd4v0	490	100	's	's	POS
cord-017161-lcqrd4v0	490	101	granulomatosis	granulomatosis	NN
cord-017161-lcqrd4v0	490	102	with	with	IN
cord-017161-lcqrd4v0	490	103	the	the	DT
cord-017161-lcqrd4v0	490	104	interleukin	interleukin	NN
cord-017161-lcqrd4v0	490	105	10	10	CD
cord-017161-lcqrd4v0	490	106	gene	gene	NN
cord-017161-lcqrd4v0	490	107	Different	different	JJ
cord-017161-lcqrd4v0	490	108	gender	gender	NN
cord-017161-lcqrd4v0	490	109	-	-	HYPH
cord-017161-lcqrd4v0	490	110	associated	associate	VBN
cord-017161-lcqrd4v0	490	111	genotype	genotype	NN
cord-017161-lcqrd4v0	490	112	risks	risk	NNS
cord-017161-lcqrd4v0	490	113	of	of	IN
cord-017161-lcqrd4v0	490	114	Wegener	Wegener	NNP
cord-017161-lcqrd4v0	490	115	's	's	POS
cord-017161-lcqrd4v0	490	116	granulomatosis	granulomatosis	NN
cord-017161-lcqrd4v0	490	117	and	and	CC
cord-017161-lcqrd4v0	490	118	microscopic	microscopic	JJ
cord-017161-lcqrd4v0	490	119	polyangiitis	polyangiitis	NN
cord-017161-lcqrd4v0	491	1	Functionally	functionally	RB
cord-017161-lcqrd4v0	491	2	relevant	relevant	JJ
cord-017161-lcqrd4v0	491	3	variations	variation	NNS
cord-017161-lcqrd4v0	491	4	of	of	IN
cord-017161-lcqrd4v0	491	5	the	the	DT
cord-017161-lcqrd4v0	491	6	interleukin	interleukin	NN
cord-017161-lcqrd4v0	491	7	10	10	CD
cord-017161-lcqrd4v0	491	8	gene	gene	NN
cord-017161-lcqrd4v0	491	9	associated	associate	VBN
cord-017161-lcqrd4v0	491	10	with	with	IN
cord-017161-lcqrd4v0	491	11	antineutrophil	antineutrophil	JJ
cord-017161-lcqrd4v0	491	12	cytoplasmic	cytoplasmic	JJ
cord-017161-lcqrd4v0	491	13	antibody	antibody	NN
cord-017161-lcqrd4v0	491	14	-	-	HYPH
cord-017161-lcqrd4v0	491	15	negative	negative	JJ
cord-017161-lcqrd4v0	491	16	Churg	Churg	NNP
cord-017161-lcqrd4v0	491	17	Strauss	Strauss	NNP
cord-017161-lcqrd4v0	491	18	syndrome	syndrome	NN
cord-017161-lcqrd4v0	491	19	,	,	,
cord-017161-lcqrd4v0	491	20	but	but	CC
cord-017161-lcqrd4v0	491	21	not	not	RB
cord-017161-lcqrd4v0	491	22	with	with	IN
cord-017161-lcqrd4v0	491	23	Wegener	Wegener	NNP
cord-017161-lcqrd4v0	491	24	's	's	POS
cord-017161-lcqrd4v0	491	25	granulomatosis	granulomatosis	NNP
cord-017161-lcqrd4v0	491	26	Association	Association	NNP
cord-017161-lcqrd4v0	491	27	of	of	IN
cord-017161-lcqrd4v0	491	28	LILRA2	LILRA2	NNP
cord-017161-lcqrd4v0	492	1	(	(	-LRB-
cord-017161-lcqrd4v0	492	2	ILT1	ILT1	NNP
cord-017161-lcqrd4v0	492	3	,	,	,
cord-017161-lcqrd4v0	492	4	LIR7	LIR7	NNP
cord-017161-lcqrd4v0	492	5	)	)	-RRB-
cord-017161-lcqrd4v0	492	6	splice	splice	NN
cord-017161-lcqrd4v0	492	7	site	site	NN
cord-017161-lcqrd4v0	492	8	polymorphism	polymorphism	NN
cord-017161-lcqrd4v0	492	9	with	with	IN
cord-017161-lcqrd4v0	492	10	systemic	systemic	JJ
cord-017161-lcqrd4v0	492	11	lupus	lupus	NN
cord-017161-lcqrd4v0	492	12	erythematosus	erythematosus	NN
cord-017161-lcqrd4v0	492	13	and	and	CC
cord-017161-lcqrd4v0	492	14	microscopic	microscopic	JJ
cord-017161-lcqrd4v0	492	15	polyangiitis	polyangiitis	NNP
cord-017161-lcqrd4v0	492	16	Novel	Novel	NNP
cord-017161-lcqrd4v0	492	17	association	association	NNP
cord-017161-lcqrd4v0	492	18	of	of	IN
cord-017161-lcqrd4v0	492	19	the	the	DT
cord-017161-lcqrd4v0	492	20	CD226	CD226	NNP
cord-017161-lcqrd4v0	492	21	(	(	-LRB-
cord-017161-lcqrd4v0	492	22	DNAM-1	DNAM-1	NNP
cord-017161-lcqrd4v0	492	23	)	)	-RRB-
cord-017161-lcqrd4v0	493	1	Gly307Ser	gly307ser	DT
cord-017161-lcqrd4v0	493	2	polymorphism	polymorphism	NN
cord-017161-lcqrd4v0	493	3	in	in	IN
cord-017161-lcqrd4v0	493	4	Wegener	Wegener	NNP
cord-017161-lcqrd4v0	493	5	's	's	POS
cord-017161-lcqrd4v0	493	6	granulomatosis	granulomatosis	NN
cord-017161-lcqrd4v0	493	7	and	and	CC
cord-017161-lcqrd4v0	493	8	con	con	NN
cord-017161-lcqrd4v0	493	9	fi	fi	NN
cord-017161-lcqrd4v0	493	10	rmation	rmation	NN
cord-017161-lcqrd4v0	493	11	for	for	IN
cord-017161-lcqrd4v0	493	12	multiple	multiple	JJ
cord-017161-lcqrd4v0	493	13	sclerosis	sclerosis	NN
cord-017161-lcqrd4v0	493	14	in	in	IN
cord-017161-lcqrd4v0	493	15	German	german	JJ
cord-017161-lcqrd4v0	493	16	patients	patient	NNS
cord-017161-lcqrd4v0	494	1	Fc	Fc	NNP
cord-017161-lcqrd4v0	494	2	receptor	receptor	NN
cord-017161-lcqrd4v0	494	3	polymorphisms	polymorphism	NNS
cord-017161-lcqrd4v0	494	4	in	in	IN
cord-017161-lcqrd4v0	494	5	Wegener	Wegener	NNP
cord-017161-lcqrd4v0	494	6	's	's	POS
cord-017161-lcqrd4v0	494	7	granulomatosis	granulomatosis	NN
cord-017161-lcqrd4v0	494	8	:	:	:
cord-017161-lcqrd4v0	494	9	risk	risk	NN
cord-017161-lcqrd4v0	494	10	factors	factor	NNS
cord-017161-lcqrd4v0	494	11	for	for	IN
cord-017161-lcqrd4v0	494	12	disease	disease	NN
cord-017161-lcqrd4v0	494	13	relapse	relapse	NN
cord-017161-lcqrd4v0	495	1	FCGR3B	FCGR3B	NNS
cord-017161-lcqrd4v0	495	2	copy	copy	NN
cord-017161-lcqrd4v0	495	3	number	number	NN
cord-017161-lcqrd4v0	495	4	variation	variation	NN
cord-017161-lcqrd4v0	495	5	is	be	VBZ
cord-017161-lcqrd4v0	495	6	associated	associate	VBN
cord-017161-lcqrd4v0	495	7	with	with	IN
cord-017161-lcqrd4v0	495	8	susceptibility	susceptibility	NN
cord-017161-lcqrd4v0	495	9	to	to	IN
cord-017161-lcqrd4v0	495	10	systemic	systemic	JJ
cord-017161-lcqrd4v0	495	11	,	,	,
cord-017161-lcqrd4v0	495	12	but	but	CC
cord-017161-lcqrd4v0	495	13	not	not	RB
cord-017161-lcqrd4v0	495	14	organ	organ	NN
cord-017161-lcqrd4v0	495	15	-	-	HYPH
cord-017161-lcqrd4v0	495	16	speci	speci	FW
cord-017161-lcqrd4v0	495	17	fi	fi	NN
cord-017161-lcqrd4v0	495	18	c	c	NN
cord-017161-lcqrd4v0	495	19	,	,	,
cord-017161-lcqrd4v0	495	20	autoimmunity	autoimmunity	NN
cord-017161-lcqrd4v0	495	21	Copy	copy	JJ
cord-017161-lcqrd4v0	495	22	number	number	NN
cord-017161-lcqrd4v0	495	23	of	of	IN
cord-017161-lcqrd4v0	495	24	FCGR3B	FCGR3B	NNS
cord-017161-lcqrd4v0	495	25	,	,	,
cord-017161-lcqrd4v0	495	26	which	which	WDT
cord-017161-lcqrd4v0	495	27	is	be	VBZ
cord-017161-lcqrd4v0	495	28	associated	associate	VBN
cord-017161-lcqrd4v0	495	29	with	with	IN
cord-017161-lcqrd4v0	495	30	systemic	systemic	JJ
cord-017161-lcqrd4v0	495	31	lupus	lupus	NN
cord-017161-lcqrd4v0	495	32	erythematosus	erythematosus	NN
cord-017161-lcqrd4v0	495	33	,	,	,
cord-017161-lcqrd4v0	495	34	correlates	correlate	VBZ
cord-017161-lcqrd4v0	495	35	with	with	IN
cord-017161-lcqrd4v0	495	36	protein	protein	NN
cord-017161-lcqrd4v0	495	37	expression	expression	NN
cord-017161-lcqrd4v0	495	38	and	and	CC
cord-017161-lcqrd4v0	495	39	immune	immune	JJ
cord-017161-lcqrd4v0	495	40	complex	complex	JJ
cord-017161-lcqrd4v0	495	41	uptake	uptake	NN
cord-017161-lcqrd4v0	495	42	Epigenetic	epigenetic	JJ
cord-017161-lcqrd4v0	495	43	basis	basis	NN
cord-017161-lcqrd4v0	495	44	for	for	IN
cord-017161-lcqrd4v0	495	45	aberrant	aberrant	JJ
cord-017161-lcqrd4v0	495	46	upregulation	upregulation	NN
cord-017161-lcqrd4v0	495	47	of	of	IN
cord-017161-lcqrd4v0	495	48	autoantigen	autoantigen	NN
cord-017161-lcqrd4v0	495	49	genes	gene	NNS
cord-017161-lcqrd4v0	495	50	in	in	IN
cord-017161-lcqrd4v0	495	51	humans	human	NNS
cord-017161-lcqrd4v0	495	52	with	with	IN
cord-017161-lcqrd4v0	495	53	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	495	54	vasculitis	vasculitis	NNP
cord-017161-lcqrd4v0	495	55	Review	Review	NNP
cord-017161-lcqrd4v0	495	56	article	article	NN
cord-017161-lcqrd4v0	495	57	:	:	:
cord-017161-lcqrd4v0	495	58	progress	progress	NN
cord-017161-lcqrd4v0	495	59	of	of	IN
cord-017161-lcqrd4v0	495	60	treatment	treatment	NN
cord-017161-lcqrd4v0	495	61	in	in	IN
cord-017161-lcqrd4v0	495	62	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	495	63	associated	associate	VBN
cord-017161-lcqrd4v0	495	64	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	496	1	The	the	DT
cord-017161-lcqrd4v0	496	2	use	use	NN
cord-017161-lcqrd4v0	496	3	of	of	IN
cord-017161-lcqrd4v0	496	4	immunosuppressive	immunosuppressive	JJ
cord-017161-lcqrd4v0	496	5	and	and	CC
cord-017161-lcqrd4v0	496	6	cytotoxic	cytotoxic	JJ
cord-017161-lcqrd4v0	496	7	drugs	drug	NNS
cord-017161-lcqrd4v0	496	8	in	in	IN
cord-017161-lcqrd4v0	496	9	non	non	JJ
cord-017161-lcqrd4v0	496	10	-	-	JJ
cord-017161-lcqrd4v0	496	11	malignant	malignant	JJ
cord-017161-lcqrd4v0	496	12	disease	disease	NN
cord-017161-lcqrd4v0	497	1	The	the	DT
cord-017161-lcqrd4v0	497	2	value	value	NN
cord-017161-lcqrd4v0	497	3	of	of	IN
cord-017161-lcqrd4v0	497	4	pulse	pulse	NN
cord-017161-lcqrd4v0	497	5	cyclophosphamide	cyclophosphamide	RB
cord-017161-lcqrd4v0	497	6	in	in	IN
cord-017161-lcqrd4v0	497	7	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	497	8	associated	associate	VBN
cord-017161-lcqrd4v0	497	9	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	497	10	:	:	:
cord-017161-lcqrd4v0	497	11	meta	meta	NNP
cord-017161-lcqrd4v0	497	12	analysis	analysis	NN
cord-017161-lcqrd4v0	497	13	and	and	CC
cord-017161-lcqrd4v0	497	14	critical	critical	JJ
cord-017161-lcqrd4v0	497	15	review	review	NN
cord-017161-lcqrd4v0	497	16	Pulse	pulse	NN
cord-017161-lcqrd4v0	497	17	versus	versus	IN
cord-017161-lcqrd4v0	497	18	daily	daily	JJ
cord-017161-lcqrd4v0	497	19	oral	oral	JJ
cord-017161-lcqrd4v0	497	20	cyclophosphamide	cyclophosphamide	NN
cord-017161-lcqrd4v0	497	21	for	for	IN
cord-017161-lcqrd4v0	497	22	induction	induction	NN
cord-017161-lcqrd4v0	497	23	of	of	IN
cord-017161-lcqrd4v0	497	24	remission	remission	NN
cord-017161-lcqrd4v0	497	25	in	in	IN
cord-017161-lcqrd4v0	497	26	antineutrophil	antineutrophil	JJ
cord-017161-lcqrd4v0	497	27	cytoplasmic	cytoplasmic	JJ
cord-017161-lcqrd4v0	497	28	antibody	antibody	NN
cord-017161-lcqrd4v0	497	29	-	-	HYPH
cord-017161-lcqrd4v0	497	30	associated	associate	VBN
cord-017161-lcqrd4v0	497	31	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	498	1	A	a	DT
cord-017161-lcqrd4v0	498	2	randomized	randomized	JJ
cord-017161-lcqrd4v0	498	3	trial	trial	NN
cord-017161-lcqrd4v0	498	4	of	of	IN
cord-017161-lcqrd4v0	498	5	maintenance	maintenance	NN
cord-017161-lcqrd4v0	498	6	therapy	therapy	NN
cord-017161-lcqrd4v0	498	7	for	for	IN
cord-017161-lcqrd4v0	498	8	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	498	9	associated	associate	VBN
cord-017161-lcqrd4v0	498	10	with	with	IN
cord-017161-lcqrd4v0	498	11	antineutrophil	antineutrophil	JJ
cord-017161-lcqrd4v0	498	12	cytoplasmic	cytoplasmic	JJ
cord-017161-lcqrd4v0	498	13	autoantibodies	autoantibody	NNS
cord-017161-lcqrd4v0	498	14	Brief	Brief	NNP
cord-017161-lcqrd4v0	498	15	communication	communication	NN
cord-017161-lcqrd4v0	498	16	:	:	:
cord-017161-lcqrd4v0	498	17	high	high	JJ
cord-017161-lcqrd4v0	498	18	incidence	incidence	NN
cord-017161-lcqrd4v0	498	19	of	of	IN
cord-017161-lcqrd4v0	498	20	venous	venous	JJ
cord-017161-lcqrd4v0	498	21	thrombotic	thrombotic	JJ
cord-017161-lcqrd4v0	498	22	events	event	NNS
cord-017161-lcqrd4v0	498	23	among	among	IN
cord-017161-lcqrd4v0	498	24	patients	patient	NNS
cord-017161-lcqrd4v0	498	25	with	with	IN
cord-017161-lcqrd4v0	498	26	Wegener	Wegener	NNP
cord-017161-lcqrd4v0	498	27	granulomatosis	granulomatosis	NNP
cord-017161-lcqrd4v0	498	28	:	:	:
cord-017161-lcqrd4v0	498	29	the	the	DT
cord-017161-lcqrd4v0	498	30	Wegener	Wegener	NNP
cord-017161-lcqrd4v0	498	31	's	's	POS
cord-017161-lcqrd4v0	498	32	clinical	clinical	JJ
cord-017161-lcqrd4v0	498	33	occurrence	occurrence	NN
cord-017161-lcqrd4v0	498	34	of	of	IN
cord-017161-lcqrd4v0	498	35	thrombosis	thrombosis	NN
cord-017161-lcqrd4v0	498	36	(	(	-LRB-
cord-017161-lcqrd4v0	498	37	WeCLOT	WeCLOT	NNP
cord-017161-lcqrd4v0	498	38	)	)	-RRB-
cord-017161-lcqrd4v0	498	39	study	study	NN
cord-017161-lcqrd4v0	498	40	Randomized	randomized	JJ
cord-017161-lcqrd4v0	498	41	trial	trial	NN
cord-017161-lcqrd4v0	498	42	of	of	IN
cord-017161-lcqrd4v0	498	43	cyclophosphamide	cyclophosphamide	NN
cord-017161-lcqrd4v0	498	44	versus	versus	IN
cord-017161-lcqrd4v0	498	45	methotrexate	methotrexate	NNP
cord-017161-lcqrd4v0	498	46	for	for	IN
cord-017161-lcqrd4v0	498	47	induction	induction	NN
cord-017161-lcqrd4v0	498	48	of	of	IN
cord-017161-lcqrd4v0	498	49	remission	remission	NN
cord-017161-lcqrd4v0	498	50	in	in	IN
cord-017161-lcqrd4v0	498	51	early	early	JJ
cord-017161-lcqrd4v0	498	52	systemic	systemic	JJ
cord-017161-lcqrd4v0	498	53	antineutrophil	antineutrophil	JJ
cord-017161-lcqrd4v0	498	54	cytoplasmic	cytoplasmic	JJ
cord-017161-lcqrd4v0	498	55	antibody	antibody	NN
cord-017161-lcqrd4v0	498	56	-	-	HYPH
cord-017161-lcqrd4v0	498	57	associated	associate	VBN
cord-017161-lcqrd4v0	498	58	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	498	59	Cyclophosphamide	Cyclophosphamide	NNP
cord-017161-lcqrd4v0	498	60	treatment	treatment	NN
cord-017161-lcqrd4v0	498	61	in	in	IN
cord-017161-lcqrd4v0	498	62	systemic	systemic	JJ
cord-017161-lcqrd4v0	498	63	necrotizing	necrotize	VBG
cord-017161-lcqrd4v0	498	64	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	498	65	and	and	CC
cord-017161-lcqrd4v0	498	66	lupus	lupus	NN
cord-017161-lcqrd4v0	498	67	nephritis	nephritis	NN
cord-017161-lcqrd4v0	498	68	.	.	.
cord-017161-lcqrd4v0	499	1	How	how	WRB
cord-017161-lcqrd4v0	499	2	long	long	JJ
cord-017161-lcqrd4v0	499	3	?	?	.
cord-017161-lcqrd4v0	500	1	How	how	WRB
cord-017161-lcqrd4v0	500	2	much	much	JJ
cord-017161-lcqrd4v0	500	3	?	?	.
cord-017161-lcqrd4v0	501	1	A	a	DT
cord-017161-lcqrd4v0	501	2	pilot	pilot	NN
cord-017161-lcqrd4v0	501	3	study	study	NN
cord-017161-lcqrd4v0	501	4	using	use	VBG
cord-017161-lcqrd4v0	501	5	mycophenolate	mycophenolate	NNP
cord-017161-lcqrd4v0	501	6	mofetil	mofetil	NNP
cord-017161-lcqrd4v0	501	7	in	in	IN
cord-017161-lcqrd4v0	501	8	relapsing	relapse	VBG
cord-017161-lcqrd4v0	501	9	or	or	CC
cord-017161-lcqrd4v0	501	10	resistant	resistant	JJ
cord-017161-lcqrd4v0	501	11	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	501	12	small	small	JJ
cord-017161-lcqrd4v0	501	13	vessel	vessel	NN
cord-017161-lcqrd4v0	501	14	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	501	15	Long	long	JJ
cord-017161-lcqrd4v0	501	16	term	term	NN
cord-017161-lcqrd4v0	501	17	comparison	comparison	NN
cord-017161-lcqrd4v0	501	18	of	of	IN
cord-017161-lcqrd4v0	501	19	rituximab	rituximab	JJ
cord-017161-lcqrd4v0	501	20	treatment	treatment	NN
cord-017161-lcqrd4v0	501	21	for	for	IN
cord-017161-lcqrd4v0	501	22	refractory	refractory	JJ
cord-017161-lcqrd4v0	501	23	systemic	systemic	JJ
cord-017161-lcqrd4v0	501	24	lupus	lupus	NN
cord-017161-lcqrd4v0	501	25	erythematosus	erythematosus	NN
cord-017161-lcqrd4v0	501	26	and	and	CC
cord-017161-lcqrd4v0	501	27	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	501	28	:	:	:
cord-017161-lcqrd4v0	501	29	remission	remission	NN
cord-017161-lcqrd4v0	501	30	,	,	,
cord-017161-lcqrd4v0	501	31	relapse	relapse	NN
cord-017161-lcqrd4v0	501	32	,	,	,
cord-017161-lcqrd4v0	501	33	and	and	CC
cord-017161-lcqrd4v0	501	34	re	re	VBP
cord-017161-lcqrd4v0	501	35	treatment	treatment	NN
cord-017161-lcqrd4v0	501	36	Rituximab	Rituximab	NNP
cord-017161-lcqrd4v0	501	37	versus	versus	IN
cord-017161-lcqrd4v0	501	38	cyclophosphamide	cyclophosphamide	NN
cord-017161-lcqrd4v0	501	39	in	in	IN
cord-017161-lcqrd4v0	501	40	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	501	41	-	-	HYPH
cord-017161-lcqrd4v0	501	42	associated	associate	VBN
cord-017161-lcqrd4v0	501	43	renal	renal	JJ
cord-017161-lcqrd4v0	501	44	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	501	45	Rituximab	Rituximab	NNPS
cord-017161-lcqrd4v0	501	46	versus	versus	IN
cord-017161-lcqrd4v0	501	47	cyclophosphamide	cyclophosphamide	RB
cord-017161-lcqrd4v0	501	48	for	for	IN
cord-017161-lcqrd4v0	501	49	ANCAassociated	ancaassociated	JJ
cord-017161-lcqrd4v0	501	50	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	501	51	Biologic	biologic	JJ
cord-017161-lcqrd4v0	501	52	therapy	therapy	NN
cord-017161-lcqrd4v0	501	53	in	in	IN
cord-017161-lcqrd4v0	501	54	primary	primary	JJ
cord-017161-lcqrd4v0	501	55	systemic	systemic	JJ
cord-017161-lcqrd4v0	501	56	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	501	57	of	of	IN
cord-017161-lcqrd4v0	501	58	the	the	DT
cord-017161-lcqrd4v0	501	59	young	young	JJ
cord-017161-lcqrd4v0	501	60	Clinical	clinical	JJ
cord-017161-lcqrd4v0	501	61	features	feature	NNS
cord-017161-lcqrd4v0	501	62	in	in	IN
cord-017161-lcqrd4v0	501	63	17	17	CD
cord-017161-lcqrd4v0	501	64	paediatric	paediatric	JJ
cord-017161-lcqrd4v0	501	65	patients	patient	NNS
cord-017161-lcqrd4v0	501	66	with	with	IN
cord-017161-lcqrd4v0	501	67	Wegener	Wegener	NNP
cord-017161-lcqrd4v0	501	68	granulomatosis	granulomatosis	NNP
cord-017161-lcqrd4v0	501	69	Clinical	clinical	JJ
cord-017161-lcqrd4v0	501	70	features	feature	NNS
cord-017161-lcqrd4v0	501	71	and	and	CC
cord-017161-lcqrd4v0	501	72	outcome	outcome	NN
cord-017161-lcqrd4v0	501	73	of	of	IN
cord-017161-lcqrd4v0	501	74	pediatric	pediatric	JJ
cord-017161-lcqrd4v0	501	75	Wegener	Wegener	NNP
cord-017161-lcqrd4v0	501	76	's	's	POS
cord-017161-lcqrd4v0	501	77	granulomatosis	granulomatosis	NN
cord-017161-lcqrd4v0	501	78	Childhood	Childhood	NNP
cord-017161-lcqrd4v0	501	79	microscopic	microscopic	JJ
cord-017161-lcqrd4v0	501	80	polyangiitis	polyangiitis	NN
cord-017161-lcqrd4v0	501	81	associated	associate	VBN
cord-017161-lcqrd4v0	501	82	with	with	IN
cord-017161-lcqrd4v0	501	83	MPO	MPO	NNP
cord-017161-lcqrd4v0	501	84	-	-	HYPH
cord-017161-lcqrd4v0	501	85	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	501	86	Churg	Churg	NNP
cord-017161-lcqrd4v0	501	87	-	-	HYPH
cord-017161-lcqrd4v0	501	88	Strauss	Strauss	NNP
cord-017161-lcqrd4v0	501	89	syndrome	syndrome	NN
cord-017161-lcqrd4v0	501	90	in	in	IN
cord-017161-lcqrd4v0	501	91	childhood	childhood	NN
cord-017161-lcqrd4v0	501	92	:	:	:
cord-017161-lcqrd4v0	501	93	a	a	DT
cord-017161-lcqrd4v0	501	94	systematic	systematic	JJ
cord-017161-lcqrd4v0	501	95	literature	literature	NN
cord-017161-lcqrd4v0	501	96	review	review	NN
cord-017161-lcqrd4v0	501	97	and	and	CC
cord-017161-lcqrd4v0	501	98	clinical	clinical	JJ
cord-017161-lcqrd4v0	501	99	comparison	comparison	NN
cord-017161-lcqrd4v0	501	100	with	with	IN
cord-017161-lcqrd4v0	501	101	adult	adult	NN
cord-017161-lcqrd4v0	501	102	patients	patient	NNS
cord-017161-lcqrd4v0	501	103	Chronic	Chronic	NNP
cord-017161-lcqrd4v0	501	104	parvovirus	parvovirus	NN
cord-017161-lcqrd4v0	501	105	B19	B19	NNP
cord-017161-lcqrd4v0	501	106	infection	infection	NN
cord-017161-lcqrd4v0	501	107	and	and	CC
cord-017161-lcqrd4v0	501	108	systemic	systemic	JJ
cord-017161-lcqrd4v0	501	109	necrotising	necrotise	VBG
cord-017161-lcqrd4v0	501	110	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	501	111	:	:	:
cord-017161-lcqrd4v0	501	112	opportunistic	opportunistic	JJ
cord-017161-lcqrd4v0	501	113	infection	infection	NN
cord-017161-lcqrd4v0	501	114	or	or	CC
cord-017161-lcqrd4v0	501	115	aetiological	aetiological	JJ
cord-017161-lcqrd4v0	501	116	agent	agent	NN
cord-017161-lcqrd4v0	501	117	?	?	.
cord-017161-lcqrd4v0	502	1	Cytomegalovirus	Cytomegalovirus	NNP
cord-017161-lcqrd4v0	502	2	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	502	3	.	.	.
cord-017161-lcqrd4v0	503	1	Case	case	NN
cord-017161-lcqrd4v0	503	2	reports	report	NNS
cord-017161-lcqrd4v0	503	3	and	and	CC
cord-017161-lcqrd4v0	503	4	review	review	NN
cord-017161-lcqrd4v0	503	5	of	of	IN
cord-017161-lcqrd4v0	503	6	the	the	DT
cord-017161-lcqrd4v0	503	7	literature	literature	NN
cord-017161-lcqrd4v0	503	8	Vasculitides	vasculitide	VBZ
cord-017161-lcqrd4v0	503	9	secondary	secondary	JJ
cord-017161-lcqrd4v0	503	10	to	to	IN
cord-017161-lcqrd4v0	503	11	infections	infection	NNS
cord-017161-lcqrd4v0	503	12	Vasculitides	vasculitide	NNS
cord-017161-lcqrd4v0	503	13	associated	associate	VBN
cord-017161-lcqrd4v0	503	14	with	with	IN
cord-017161-lcqrd4v0	503	15	malignancies	malignancy	NNS
cord-017161-lcqrd4v0	503	16	:	:	:
cord-017161-lcqrd4v0	503	17	analysis	analysis	NN
cord-017161-lcqrd4v0	503	18	of	of	IN
cord-017161-lcqrd4v0	503	19	sixty	sixty	CD
cord-017161-lcqrd4v0	503	20	patients	patient	NNS
cord-017161-lcqrd4v0	503	21	Juvenile	juvenile	JJ
cord-017161-lcqrd4v0	503	22	polyarteritis	polyarteritis	NN
cord-017161-lcqrd4v0	503	23	:	:	:
cord-017161-lcqrd4v0	503	24	results	result	NNS
cord-017161-lcqrd4v0	503	25	of	of	IN
cord-017161-lcqrd4v0	503	26	a	a	DT
cord-017161-lcqrd4v0	503	27	multicenter	multicenter	JJ
cord-017161-lcqrd4v0	503	28	survey	survey	NN
cord-017161-lcqrd4v0	503	29	of	of	IN
cord-017161-lcqrd4v0	503	30	110	110	CD
cord-017161-lcqrd4v0	503	31	children	child	NNS
cord-017161-lcqrd4v0	503	32	Pathogenesis	Pathogenesis	NNP
cord-017161-lcqrd4v0	503	33	of	of	IN
cord-017161-lcqrd4v0	503	34	vasculitis	vasculitis	JJ
cord-017161-lcqrd4v0	503	35	Role	role	NN
cord-017161-lcqrd4v0	503	36	of	of	IN
cord-017161-lcqrd4v0	503	37	immune	immune	JJ
cord-017161-lcqrd4v0	503	38	complexes	complex	NNS
cord-017161-lcqrd4v0	503	39	involving	involve	VBG
cord-017161-lcqrd4v0	503	40	sh	sh	NNP
cord-017161-lcqrd4v0	503	41	antigen	antigen	NNP
cord-017161-lcqrd4v0	503	42	in	in	IN
cord-017161-lcqrd4v0	503	43	pathogenesis	pathogenesis	NN
cord-017161-lcqrd4v0	503	44	of	of	IN
cord-017161-lcqrd4v0	503	45	chronic	chronic	JJ
cord-017161-lcqrd4v0	503	46	active	active	JJ
cord-017161-lcqrd4v0	503	47	hepatitis	hepatitis	NN
cord-017161-lcqrd4v0	503	48	and	and	CC
cord-017161-lcqrd4v0	503	49	polyarteritis	polyarteritis	NNP
cord-017161-lcqrd4v0	504	1	nodosa	nodosa	NNP
cord-017161-lcqrd4v0	504	2	Vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	504	3	of	of	IN
cord-017161-lcqrd4v0	504	4	peripheral	peripheral	JJ
cord-017161-lcqrd4v0	504	5	nerve	nerve	NN
cord-017161-lcqrd4v0	504	6	and	and	CC
cord-017161-lcqrd4v0	504	7	skeletal	skeletal	JJ
cord-017161-lcqrd4v0	504	8	muscle	muscle	NN
cord-017161-lcqrd4v0	504	9	:	:	:
cord-017161-lcqrd4v0	504	10	clinicopathological	clinicopathological	NNP
cord-017161-lcqrd4v0	504	11	correlation	correlation	NN
cord-017161-lcqrd4v0	504	12	and	and	CC
cord-017161-lcqrd4v0	504	13	immunopathic	immunopathic	JJ
cord-017161-lcqrd4v0	504	14	mechanisms	mechanism	NNS
cord-017161-lcqrd4v0	505	1	Polyarteritis	Polyarteritis	NNP
cord-017161-lcqrd4v0	505	2	nodosa	nodosa	RB
cord-017161-lcqrd4v0	505	3	revisited	revisit	VBD
cord-017161-lcqrd4v0	505	4	Polyarteritis	Polyarteritis	NNP
cord-017161-lcqrd4v0	505	5	nodosa	nodosa	RB
cord-017161-lcqrd4v0	505	6	in	in	IN
cord-017161-lcqrd4v0	505	7	a	a	DT
cord-017161-lcqrd4v0	505	8	cynomolgus	cynomolgus	JJ
cord-017161-lcqrd4v0	505	9	macaque	macaque	NN
cord-017161-lcqrd4v0	505	10	(	(	-LRB-
cord-017161-lcqrd4v0	505	11	Macaca	Macaca	NNP
cord-017161-lcqrd4v0	505	12	fascicularis	fascicularis	NN
cord-017161-lcqrd4v0	505	13	)	)	-RRB-
cord-017161-lcqrd4v0	506	1	Pathologic	pathologic	JJ
cord-017161-lcqrd4v0	506	2	features	feature	NNS
cord-017161-lcqrd4v0	506	3	of	of	IN
cord-017161-lcqrd4v0	506	4	naturally	naturally	RB
cord-017161-lcqrd4v0	506	5	occurring	occur	VBG
cord-017161-lcqrd4v0	506	6	juvenile	juvenile	JJ
cord-017161-lcqrd4v0	506	7	polyarteritis	polyarteritis	NN
cord-017161-lcqrd4v0	506	8	in	in	IN
cord-017161-lcqrd4v0	506	9	beagle	beagle	NNP
cord-017161-lcqrd4v0	506	10	dogs	dog	NNS
cord-017161-lcqrd4v0	506	11	Familial	familial	JJ
cord-017161-lcqrd4v0	506	12	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	506	13	:	:	:
cord-017161-lcqrd4v0	507	1	report	report	NN
cord-017161-lcqrd4v0	507	2	of	of	IN
cord-017161-lcqrd4v0	507	3	2	2	CD
cord-017161-lcqrd4v0	507	4	families	family	NNS
cord-017161-lcqrd4v0	507	5	Familial	familial	JJ
cord-017161-lcqrd4v0	507	6	polyarteritis	polyarteritis	NN
cord-017161-lcqrd4v0	507	7	nodosa	nodosa	NN
cord-017161-lcqrd4v0	507	8	Familial	familial	JJ
cord-017161-lcqrd4v0	507	9	polyarteritis	polyarteritis	NNP
cord-017161-lcqrd4v0	507	10	nodosa	nodosa	RB
cord-017161-lcqrd4v0	507	11	:	:	:
cord-017161-lcqrd4v0	507	12	a	a	DT
cord-017161-lcqrd4v0	507	13	serologic	serologic	NNP
cord-017161-lcqrd4v0	507	14	and	and	CC
cord-017161-lcqrd4v0	507	15	immunogenetic	immunogenetic	JJ
cord-017161-lcqrd4v0	507	16	analysis	analysis	NN
cord-017161-lcqrd4v0	507	17	Prevalence	prevalence	NN
cord-017161-lcqrd4v0	507	18	of	of	IN
cord-017161-lcqrd4v0	507	19	the	the	DT
cord-017161-lcqrd4v0	507	20	MEFV	MEFV	NNP
cord-017161-lcqrd4v0	507	21	gene	gene	NN
cord-017161-lcqrd4v0	507	22	mutations	mutation	NNS
cord-017161-lcqrd4v0	507	23	in	in	IN
cord-017161-lcqrd4v0	507	24	childhood	childhood	NN
cord-017161-lcqrd4v0	507	25	polyarteritis	polyarteritis	NN
cord-017161-lcqrd4v0	507	26	nodosa	nodosa	RB
cord-017161-lcqrd4v0	507	27	Cyclophosphamide	Cyclophosphamide	NNP
cord-017161-lcqrd4v0	507	28	therapy	therapy	NN
cord-017161-lcqrd4v0	507	29	of	of	IN
cord-017161-lcqrd4v0	507	30	severe	severe	JJ
cord-017161-lcqrd4v0	507	31	systemic	systemic	JJ
cord-017161-lcqrd4v0	507	32	necrotizing	necrotize	VBG
cord-017161-lcqrd4v0	507	33	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	507	34	Current	current	JJ
cord-017161-lcqrd4v0	507	35	attitudes	attitude	NNS
cord-017161-lcqrd4v0	507	36	to	to	IN
cord-017161-lcqrd4v0	507	37	the	the	DT
cord-017161-lcqrd4v0	507	38	therapy	therapy	NN
cord-017161-lcqrd4v0	507	39	of	of	IN
cord-017161-lcqrd4v0	507	40	vasculitis	vasculitis	NNP
cord-017161-lcqrd4v0	507	41	Vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	507	42	in	in	IN
cord-017161-lcqrd4v0	507	43	children	child	NNS
cord-017161-lcqrd4v0	507	44	Advances	advance	VBZ
cord-017161-lcqrd4v0	507	45	in	in	IN
cord-017161-lcqrd4v0	507	46	childhood	childhood	NN
cord-017161-lcqrd4v0	507	47	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	507	48	Childhood	Childhood	NNP
cord-017161-lcqrd4v0	507	49	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	507	50	and	and	CC
cord-017161-lcqrd4v0	507	51	plasma	plasma	NN
cord-017161-lcqrd4v0	507	52	exchange	exchange	NN
cord-017161-lcqrd4v0	508	1	In	in	IN
cord-017161-lcqrd4v0	508	2	fl	fl	NNP
cord-017161-lcqrd4v0	508	3	iximab	iximab	NNS
cord-017161-lcqrd4v0	508	4	in	in	IN
cord-017161-lcqrd4v0	508	5	a	a	DT
cord-017161-lcqrd4v0	508	6	child	child	NN
cord-017161-lcqrd4v0	508	7	with	with	IN
cord-017161-lcqrd4v0	508	8	therapy	therapy	NN
cord-017161-lcqrd4v0	508	9	-	-	HYPH
cord-017161-lcqrd4v0	508	10	resistant	resistant	JJ
cord-017161-lcqrd4v0	508	11	systemic	systemic	JJ
cord-017161-lcqrd4v0	508	12	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	509	1	A	a	DT
cord-017161-lcqrd4v0	509	2	case	case	NN
cord-017161-lcqrd4v0	509	3	of	of	IN
cord-017161-lcqrd4v0	509	4	polyarteritis	polyarteritis	NN
cord-017161-lcqrd4v0	509	5	nodosa	nodosa	NNP
cord-017161-lcqrd4v0	509	6	successfully	successfully	RB
cord-017161-lcqrd4v0	509	7	treated	treat	VBN
cord-017161-lcqrd4v0	509	8	by	by	IN
cord-017161-lcqrd4v0	509	9	rituximab	rituximab	JJ
cord-017161-lcqrd4v0	509	10	Refractory	refractory	JJ
cord-017161-lcqrd4v0	509	11	polyarteritis	polyarteritis	NN
cord-017161-lcqrd4v0	509	12	nodosa	nodosa	RB
cord-017161-lcqrd4v0	509	13	successfully	successfully	RB
cord-017161-lcqrd4v0	509	14	treated	treat	VBN
cord-017161-lcqrd4v0	509	15	with	with	IN
cord-017161-lcqrd4v0	509	16	in	in	IN
cord-017161-lcqrd4v0	509	17	fl	fl	NNP
cord-017161-lcqrd4v0	509	18	iximab	iximab	NNS
cord-017161-lcqrd4v0	509	19	A	a	DT
cord-017161-lcqrd4v0	509	20	new	new	JJ
cord-017161-lcqrd4v0	509	21	treatment	treatment	NN
cord-017161-lcqrd4v0	509	22	for	for	IN
cord-017161-lcqrd4v0	509	23	polyarteritis	polyarteritis	NN
cord-017161-lcqrd4v0	510	1	nodosa	nodosa	RB
cord-017161-lcqrd4v0	510	2	Treating	treat	VBG
cord-017161-lcqrd4v0	510	3	polyrteritis	polyrteritis	NN
cord-017161-lcqrd4v0	510	4	nodosa	nodosa	RB
cord-017161-lcqrd4v0	510	5	;	;	,
cord-017161-lcqrd4v0	510	6	current	current	JJ
cord-017161-lcqrd4v0	510	7	state	state	NN
cord-017161-lcqrd4v0	510	8	of	of	IN
cord-017161-lcqrd4v0	510	9	art	art	NN
cord-017161-lcqrd4v0	510	10	Large	large	JJ
cord-017161-lcqrd4v0	510	11	vessel	vessel	NN
cord-017161-lcqrd4v0	510	12	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	510	13	Takayasu	Takayasu	NNP
cord-017161-lcqrd4v0	510	14	arteritis	arteritis	NN
cord-017161-lcqrd4v0	510	15	insights	insight	NNS
cord-017161-lcqrd4v0	510	16	into	into	IN
cord-017161-lcqrd4v0	510	17	immunopathology	immunopathology	NN
cord-017161-lcqrd4v0	510	18	Antigenic	antigenic	JJ
cord-017161-lcqrd4v0	510	19	targets	target	NNS
cord-017161-lcqrd4v0	510	20	and	and	CC
cord-017161-lcqrd4v0	510	21	pathogenicity	pathogenicity	NN
cord-017161-lcqrd4v0	510	22	of	of	IN
cord-017161-lcqrd4v0	510	23	anti	anti	JJ
cord-017161-lcqrd4v0	510	24	-	-	JJ
cord-017161-lcqrd4v0	510	25	aortic	aortic	JJ
cord-017161-lcqrd4v0	510	26	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	510	27	cell	cell	NN
cord-017161-lcqrd4v0	510	28	antibodies	antibody	NNS
cord-017161-lcqrd4v0	510	29	in	in	IN
cord-017161-lcqrd4v0	510	30	Takayasu	Takayasu	NNP
cord-017161-lcqrd4v0	510	31	arteritis	arteritis	NN
cord-017161-lcqrd4v0	510	32	Reactivity	reactivity	NN
cord-017161-lcqrd4v0	510	33	of	of	IN
cord-017161-lcqrd4v0	510	34	gamma	gamma	NN
cord-017161-lcqrd4v0	510	35	/	/	SYM
cord-017161-lcqrd4v0	510	36	delta	delta	NN
cord-017161-lcqrd4v0	510	37	T	T	NNP
cord-017161-lcqrd4v0	510	38	cells	cell	NNS
cord-017161-lcqrd4v0	510	39	to	to	IN
cord-017161-lcqrd4v0	510	40	human	human	NN
cord-017161-lcqrd4v0	510	41	60	60	CD
cord-017161-lcqrd4v0	510	42	kd	kd	NNP
cord-017161-lcqrd4v0	510	43	heat	heat	NN
cord-017161-lcqrd4v0	510	44	shock	shock	NN
cord-017161-lcqrd4v0	510	45	protein	protein	NN
cord-017161-lcqrd4v0	510	46	and	and	CC
cord-017161-lcqrd4v0	510	47	their	-PRON-	PRP$
cord-017161-lcqrd4v0	510	48	cytotoxicity	cytotoxicity	NN
cord-017161-lcqrd4v0	510	49	to	to	IN
cord-017161-lcqrd4v0	510	50	aortic	aortic	JJ
cord-017161-lcqrd4v0	510	51	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	510	52	cells	cell	NNS
cord-017161-lcqrd4v0	510	53	in	in	IN
cord-017161-lcqrd4v0	510	54	Takayasu	Takayasu	NNP
cord-017161-lcqrd4v0	510	55	arteritis	arteritis	NN
cord-017161-lcqrd4v0	510	56	Non	Non	NNP
cord-017161-lcqrd4v0	510	57	-	-	NN
cord-017161-lcqrd4v0	510	58	speci	speci	JJ
cord-017161-lcqrd4v0	510	59	fi	fi	NN
cord-017161-lcqrd4v0	510	60	c	c	NN
cord-017161-lcqrd4v0	510	61	arteritis	arteritis	NN
cord-017161-lcqrd4v0	510	62	of	of	IN
cord-017161-lcqrd4v0	510	63	the	the	DT
cord-017161-lcqrd4v0	510	64	aorta	aorta	NN
cord-017161-lcqrd4v0	510	65	and	and	CC
cord-017161-lcqrd4v0	510	66	its	-PRON-	PRP$
cord-017161-lcqrd4v0	510	67	main	main	JJ
cord-017161-lcqrd4v0	510	68	branches	branch	NNS
cord-017161-lcqrd4v0	510	69	Familial	Familial	NNP
cord-017161-lcqrd4v0	510	70	Takayasu	Takayasu	NNP
cord-017161-lcqrd4v0	510	71	arteritis	arteritis	NN
cord-017161-lcqrd4v0	510	72	-	-	:
cord-017161-lcqrd4v0	510	73	a	a	DT
cord-017161-lcqrd4v0	510	74	pediatric	pediatric	JJ
cord-017161-lcqrd4v0	510	75	case	case	NN
cord-017161-lcqrd4v0	510	76	and	and	CC
cord-017161-lcqrd4v0	510	77	a	a	DT
cord-017161-lcqrd4v0	510	78	review	review	NN
cord-017161-lcqrd4v0	510	79	of	of	IN
cord-017161-lcqrd4v0	510	80	the	the	DT
cord-017161-lcqrd4v0	510	81	literature	literature	NN
cord-017161-lcqrd4v0	510	82	Comparative	Comparative	NNP
cord-017161-lcqrd4v0	510	83	study	study	NN
cord-017161-lcqrd4v0	510	84	of	of	IN
cord-017161-lcqrd4v0	510	85	the	the	DT
cord-017161-lcqrd4v0	510	86	residues	residue	NNS
cord-017161-lcqrd4v0	510	87	63	63	CD
cord-017161-lcqrd4v0	510	88	and	and	CC
cord-017161-lcqrd4v0	510	89	67	67	CD
cord-017161-lcqrd4v0	510	90	on	on	IN
cord-017161-lcqrd4v0	510	91	the	the	DT
cord-017161-lcqrd4v0	510	92	HLA	HLA	NNP
cord-017161-lcqrd4v0	510	93	-	-	HYPH
cord-017161-lcqrd4v0	510	94	B	B	NNP
cord-017161-lcqrd4v0	510	95	molecule	molecule	NN
cord-017161-lcqrd4v0	510	96	in	in	IN
cord-017161-lcqrd4v0	510	97	patients	patient	NNS
cord-017161-lcqrd4v0	510	98	with	with	IN
cord-017161-lcqrd4v0	510	99	Takayasu	Takayasu	NNP
cord-017161-lcqrd4v0	510	100	's	's	POS
cord-017161-lcqrd4v0	510	101	arteritis	arteritis	NN
cord-017161-lcqrd4v0	510	102	Comprehensive	comprehensive	JJ
cord-017161-lcqrd4v0	510	103	analysis	analysis	NN
cord-017161-lcqrd4v0	510	104	of	of	IN
cord-017161-lcqrd4v0	510	105	HLA	HLA	NNP
cord-017161-lcqrd4v0	510	106	genes	gene	NNS
cord-017161-lcqrd4v0	510	107	in	in	IN
cord-017161-lcqrd4v0	510	108	Takayasu	Takayasu	NNP
cord-017161-lcqrd4v0	510	109	arteritis	arteritis	NN
cord-017161-lcqrd4v0	510	110	in	in	IN
cord-017161-lcqrd4v0	510	111	Japan	Japan	NNP
cord-017161-lcqrd4v0	510	112	Takayasu	Takayasu	NNP
cord-017161-lcqrd4v0	510	113	arteritis	arteritis	NN
cord-017161-lcqrd4v0	510	114	in	in	IN
cord-017161-lcqrd4v0	510	115	children	child	NNS
cord-017161-lcqrd4v0	510	116	Takayasu	Takayasu	NNP
cord-017161-lcqrd4v0	510	117	arteritis	arteritis	NN
cord-017161-lcqrd4v0	510	118	in	in	IN
cord-017161-lcqrd4v0	510	119	children	child	NNS
cord-017161-lcqrd4v0	510	120	:	:	:
cord-017161-lcqrd4v0	510	121	preliminary	preliminary	JJ
cord-017161-lcqrd4v0	510	122	experience	experience	NN
cord-017161-lcqrd4v0	510	123	with	with	IN
cord-017161-lcqrd4v0	510	124	cyclophosphamide	cyclophosphamide	JJ
cord-017161-lcqrd4v0	510	125	induction	induction	NN
cord-017161-lcqrd4v0	510	126	and	and	CC
cord-017161-lcqrd4v0	510	127	corticosteroids	corticosteroid	NNS
cord-017161-lcqrd4v0	511	1	followed	follow	VBN
cord-017161-lcqrd4v0	511	2	by	by	IN
cord-017161-lcqrd4v0	511	3	methotrexate	methotrexate	NNP
cord-017161-lcqrd4v0	511	4	Antiûtumor	Antiûtumor	NNP
cord-017161-lcqrd4v0	511	5	necrosis	necrosis	NN
cord-017161-lcqrd4v0	511	6	factor	factor	NN
cord-017161-lcqrd4v0	511	7	therapy	therapy	NN
cord-017161-lcqrd4v0	511	8	in	in	IN
cord-017161-lcqrd4v0	511	9	patients	patient	NNS
cord-017161-lcqrd4v0	511	10	with	with	IN
cord-017161-lcqrd4v0	511	11	dif	dif	NNP
cord-017161-lcqrd4v0	511	12	fi	fi	NN
cord-017161-lcqrd4v0	511	13	cult	cult	NN
cord-017161-lcqrd4v0	511	14	to	to	TO
cord-017161-lcqrd4v0	511	15	treat	treat	VB
cord-017161-lcqrd4v0	511	16	Takayasu	Takayasu	NNP
cord-017161-lcqrd4v0	511	17	arteritis	arteritis	NN
cord-017161-lcqrd4v0	512	1	Circulating	circulate	VBG
cord-017161-lcqrd4v0	512	2	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	512	3	cells	cell	NNS
cord-017161-lcqrd4v0	512	4	,	,	,
cord-017161-lcqrd4v0	512	5	microparticles	microparticle	NNS
cord-017161-lcqrd4v0	512	6	and	and	CC
cord-017161-lcqrd4v0	512	7	progenitors	progenitor	NNS
cord-017161-lcqrd4v0	512	8	:	:	:
cord-017161-lcqrd4v0	513	1	key	key	JJ
cord-017161-lcqrd4v0	513	2	players	player	NNS
cord-017161-lcqrd4v0	513	3	towards	towards	IN
cord-017161-lcqrd4v0	513	4	the	the	DT
cord-017161-lcqrd4v0	513	5	de	de	FW
cord-017161-lcqrd4v0	513	6	fi	fi	NNP
cord-017161-lcqrd4v0	513	7	nition	nition	NN
cord-017161-lcqrd4v0	513	8	of	of	IN
cord-017161-lcqrd4v0	513	9	vascular	vascular	JJ
cord-017161-lcqrd4v0	513	10	competence	competence	NN
cord-017161-lcqrd4v0	513	11	Biomechanical	biomechanical	JJ
cord-017161-lcqrd4v0	513	12	activation	activation	NN
cord-017161-lcqrd4v0	513	13	:	:	:
cord-017161-lcqrd4v0	513	14	an	an	DT
cord-017161-lcqrd4v0	513	15	emerging	emerge	VBG
cord-017161-lcqrd4v0	513	16	paradigm	paradigm	NN
cord-017161-lcqrd4v0	513	17	in	in	IN
cord-017161-lcqrd4v0	513	18	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	513	19	adhesion	adhesion	NN
cord-017161-lcqrd4v0	513	20	biology	biology	NN
cord-017161-lcqrd4v0	513	21	Procoagulant	Procoagulant	NNP
cord-017161-lcqrd4v0	513	22	microparticles	microparticle	NNS
cord-017161-lcqrd4v0	513	23	:	:	:
cord-017161-lcqrd4v0	513	24	disrupting	disrupt	VBG
cord-017161-lcqrd4v0	513	25	the	the	DT
cord-017161-lcqrd4v0	513	26	vascular	vascular	JJ
cord-017161-lcqrd4v0	513	27	homeostasis	homeostasis	NN
cord-017161-lcqrd4v0	513	28	equation	equation	NN
cord-017161-lcqrd4v0	513	29	?	?	.
cord-017161-lcqrd4v0	514	1	Circulating	circulate	VBG
cord-017161-lcqrd4v0	514	2	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	514	3	cells	cell	NNS
cord-017161-lcqrd4v0	514	4	as	as	IN
cord-017161-lcqrd4v0	514	5	markers	marker	NNS
cord-017161-lcqrd4v0	514	6	for	for	IN
cord-017161-lcqrd4v0	514	7	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	514	8	-	-	HYPH
cord-017161-lcqrd4v0	514	9	associated	associate	VBN
cord-017161-lcqrd4v0	514	10	small	small	JJ
cord-017161-lcqrd4v0	514	11	-	-	HYPH
cord-017161-lcqrd4v0	514	12	vessel	vessel	NN
cord-017161-lcqrd4v0	514	13	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	514	14	Isolation	isolation	NN
cord-017161-lcqrd4v0	514	15	and	and	CC
cord-017161-lcqrd4v0	514	16	enumeration	enumeration	NN
cord-017161-lcqrd4v0	514	17	of	of	IN
cord-017161-lcqrd4v0	514	18	circulating	circulate	VBG
cord-017161-lcqrd4v0	514	19	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	514	20	cells	cell	NNS
cord-017161-lcqrd4v0	514	21	by	by	IN
cord-017161-lcqrd4v0	514	22	immunomagnetic	immunomagnetic	JJ
cord-017161-lcqrd4v0	514	23	isolation	isolation	NN
cord-017161-lcqrd4v0	514	24	:	:	:
cord-017161-lcqrd4v0	514	25	proposal	proposal	NN
cord-017161-lcqrd4v0	514	26	of	of	IN
cord-017161-lcqrd4v0	514	27	a	a	DT
cord-017161-lcqrd4v0	514	28	de	de	FW
cord-017161-lcqrd4v0	514	29	fi	fi	NNP
cord-017161-lcqrd4v0	514	30	nition	nition	NN
cord-017161-lcqrd4v0	514	31	and	and	CC
cord-017161-lcqrd4v0	514	32	a	a	DT
cord-017161-lcqrd4v0	514	33	consensus	consensus	NN
cord-017161-lcqrd4v0	514	34	protocol	protocol	NN
cord-017161-lcqrd4v0	514	35	Bone	Bone	NNP
cord-017161-lcqrd4v0	514	36	marrow	marrow	NN
cord-017161-lcqrd4v0	514	37	origin	origin	NN
cord-017161-lcqrd4v0	514	38	of	of	IN
cord-017161-lcqrd4v0	514	39	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	514	40	progenitor	progenitor	NN
cord-017161-lcqrd4v0	514	41	cells	cell	NNS
cord-017161-lcqrd4v0	514	42	responsible	responsible	JJ
cord-017161-lcqrd4v0	514	43	for	for	IN
cord-017161-lcqrd4v0	514	44	postnatal	postnatal	JJ
cord-017161-lcqrd4v0	514	45	vasculogenesis	vasculogenesis	NN
cord-017161-lcqrd4v0	514	46	in	in	IN
cord-017161-lcqrd4v0	514	47	physiological	physiological	JJ
cord-017161-lcqrd4v0	514	48	and	and	CC
cord-017161-lcqrd4v0	514	49	pathological	pathological	JJ
cord-017161-lcqrd4v0	514	50	neovascularization	neovascularization	NN
cord-017161-lcqrd4v0	515	1	Endothelial	endothelial	JJ
cord-017161-lcqrd4v0	515	2	injury	injury	NN
cord-017161-lcqrd4v0	515	3	and	and	CC
cord-017161-lcqrd4v0	515	4	repair	repair	NN
cord-017161-lcqrd4v0	515	5	in	in	IN
cord-017161-lcqrd4v0	515	6	systemic	systemic	JJ
cord-017161-lcqrd4v0	515	7	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	515	8	of	of	IN
cord-017161-lcqrd4v0	515	9	the	the	DT
cord-017161-lcqrd4v0	515	10	young	young	JJ
cord-017161-lcqrd4v0	515	11	Endothelial	Endothelial	NNP
cord-017161-lcqrd4v0	515	12	progenitor	progenitor	NN
cord-017161-lcqrd4v0	515	13	cells	cell	NNS
cord-017161-lcqrd4v0	515	14	and	and	CC
cord-017161-lcqrd4v0	515	15	vasculogenic	vasculogenic	JJ
cord-017161-lcqrd4v0	515	16	responses	response	NNS
cord-017161-lcqrd4v0	515	17	to	to	IN
cord-017161-lcqrd4v0	515	18	therapy	therapy	NN
cord-017161-lcqrd4v0	515	19	in	in	IN
cord-017161-lcqrd4v0	515	20	children	child	NNS
cord-017161-lcqrd4v0	515	21	with	with	IN
cord-017161-lcqrd4v0	515	22	primary	primary	JJ
cord-017161-lcqrd4v0	515	23	systemic	systemic	JJ
cord-017161-lcqrd4v0	515	24	vasculitis	vasculitis	JJ
cord-017161-lcqrd4v0	515	25	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	515	26	disease	disease	NN
cord-017161-lcqrd4v0	515	27	with	with	IN
cord-017161-lcqrd4v0	515	28	particular	particular	JJ
cord-017161-lcqrd4v0	515	29	emphasis	emphasis	NN
cord-017161-lcqrd4v0	515	30	on	on	IN
cord-017161-lcqrd4v0	515	31	arterial	arterial	JJ
cord-017161-lcqrd4v0	515	32	lesions	lesion	NNS
cord-017161-lcqrd4v0	515	33	Relationship	relationship	NN
cord-017161-lcqrd4v0	515	34	between	between	IN
cord-017161-lcqrd4v0	515	35	carotid	carotid	JJ
cord-017161-lcqrd4v0	515	36	intima	intima	NN
cord-017161-lcqrd4v0	515	37	-	-	HYPH
cord-017161-lcqrd4v0	515	38	media	medium	NNS
cord-017161-lcqrd4v0	515	39	thickness	thickness	NN
cord-017161-lcqrd4v0	515	40	and	and	CC
cord-017161-lcqrd4v0	515	41	arterial	arterial	JJ
cord-017161-lcqrd4v0	515	42	stiffness	stiffness	NN
cord-017161-lcqrd4v0	515	43	in	in	IN
cord-017161-lcqrd4v0	515	44	children	child	NNS
cord-017161-lcqrd4v0	515	45	after	after	RB
cord-017161-lcqrd4v0	516	1	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	516	2	disease	disease	NN
cord-017161-lcqrd4v0	516	3	Arterial	arterial	JJ
cord-017161-lcqrd4v0	516	4	distensibility	distensibility	NN
cord-017161-lcqrd4v0	516	5	in	in	IN
cord-017161-lcqrd4v0	516	6	children	child	NNS
cord-017161-lcqrd4v0	516	7	and	and	CC
cord-017161-lcqrd4v0	516	8	teenagers	teenager	NNS
cord-017161-lcqrd4v0	516	9	:	:	:
cord-017161-lcqrd4v0	516	10	normal	normal	JJ
cord-017161-lcqrd4v0	516	11	evolution	evolution	NN
cord-017161-lcqrd4v0	516	12	and	and	CC
cord-017161-lcqrd4v0	516	13	the	the	DT
cord-017161-lcqrd4v0	516	14	effect	effect	NN
cord-017161-lcqrd4v0	516	15	of	of	IN
cord-017161-lcqrd4v0	516	16	childhood	childhood	NN
cord-017161-lcqrd4v0	516	17	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	517	1	Circulating	circulate	VBG
cord-017161-lcqrd4v0	517	2	endothelial	endothelial	JJ
cord-017161-lcqrd4v0	517	3	cells	cell	NNS
cord-017161-lcqrd4v0	517	4	in	in	IN
cord-017161-lcqrd4v0	517	5	relapse	relapse	NN
cord-017161-lcqrd4v0	517	6	and	and	CC
cord-017161-lcqrd4v0	517	7	limited	limited	JJ
cord-017161-lcqrd4v0	517	8	granulomatous	granulomatous	JJ
cord-017161-lcqrd4v0	517	9	disease	disease	NN
cord-017161-lcqrd4v0	517	10	due	due	JJ
cord-017161-lcqrd4v0	517	11	to	to	IN
cord-017161-lcqrd4v0	517	12	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	517	13	associated	associate	VBN
cord-017161-lcqrd4v0	517	14	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	517	15	Are	be	VBP
cord-017161-lcqrd4v0	517	16	patients	patient	NNS
cord-017161-lcqrd4v0	517	17	after	after	IN
cord-017161-lcqrd4v0	517	18	Kawasaki	Kawasaki	NNP
cord-017161-lcqrd4v0	517	19	disease	disease	NN
cord-017161-lcqrd4v0	517	20	at	at	IN
cord-017161-lcqrd4v0	517	21	increased	increase	VBN
cord-017161-lcqrd4v0	517	22	risk	risk	NN
cord-017161-lcqrd4v0	517	23	for	for	IN
cord-017161-lcqrd4v0	517	24	accelerated	accelerated	JJ
cord-017161-lcqrd4v0	517	25	atherosclerosis	atherosclerosis	NN
cord-017161-lcqrd4v0	517	26	?	?	.
cord-017161-lcqrd4v0	518	1	Induction	induction	NN
cord-017161-lcqrd4v0	518	2	of	of	IN
cord-017161-lcqrd4v0	518	3	remission	remission	NN
cord-017161-lcqrd4v0	518	4	in	in	IN
cord-017161-lcqrd4v0	518	5	active	active	JJ
cord-017161-lcqrd4v0	518	6	anti	anti	JJ
cord-017161-lcqrd4v0	518	7	-	-	JJ
cord-017161-lcqrd4v0	518	8	neutrophil	neutrophil	JJ
cord-017161-lcqrd4v0	518	9	cytoplasmic	cytoplasmic	JJ
cord-017161-lcqrd4v0	518	10	antibody	antibody	NN
cord-017161-lcqrd4v0	518	11	-	-	HYPH
cord-017161-lcqrd4v0	518	12	associated	associate	VBN
cord-017161-lcqrd4v0	518	13	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	518	14	with	with	IN
cord-017161-lcqrd4v0	518	15	mycophenolate	mycophenolate	NNP
cord-017161-lcqrd4v0	518	16	mofetil	mofetil	NNP
cord-017161-lcqrd4v0	518	17	in	in	IN
cord-017161-lcqrd4v0	518	18	patients	patient	NNS
cord-017161-lcqrd4v0	518	19	who	who	WP
cord-017161-lcqrd4v0	518	20	can	can	MD
cord-017161-lcqrd4v0	518	21	not	not	RB
cord-017161-lcqrd4v0	518	22	be	be	VB
cord-017161-lcqrd4v0	518	23	treated	treat	VBN
cord-017161-lcqrd4v0	518	24	with	with	IN
cord-017161-lcqrd4v0	518	25	cyclophosphamide	cyclophosphamide	JJ
cord-017161-lcqrd4v0	518	26	ANCA	ANCA	NNP
cord-017161-lcqrd4v0	518	27	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	518	28	:	:	:
cord-017161-lcqrd4v0	518	29	time	time	NN
cord-017161-lcqrd4v0	518	30	for	for	IN
cord-017161-lcqrd4v0	518	31	a	a	DT
cord-017161-lcqrd4v0	518	32	change	change	NN
cord-017161-lcqrd4v0	518	33	in	in	IN
cord-017161-lcqrd4v0	518	34	treatment	treatment	NN
cord-017161-lcqrd4v0	518	35	paradigm	paradigm	NN
cord-017161-lcqrd4v0	518	36	?	?	.
cord-017161-lcqrd4v0	519	1	Not	not	RB
cord-017161-lcqrd4v0	519	2	yet	yet	RB
cord-017161-lcqrd4v0	519	3	Prospective	prospective	JJ
cord-017161-lcqrd4v0	519	4	study	study	NN
cord-017161-lcqrd4v0	519	5	of	of	IN
cord-017161-lcqrd4v0	519	6	TNFalpha	TNFalpha	NNP
cord-017161-lcqrd4v0	519	7	blockade	blockade	NN
cord-017161-lcqrd4v0	519	8	with	with	IN
cord-017161-lcqrd4v0	519	9	in	in	IN
cord-017161-lcqrd4v0	519	10	fl	fl	NNP
cord-017161-lcqrd4v0	519	11	iximab	iximab	NNS
cord-017161-lcqrd4v0	519	12	in	in	IN
cord-017161-lcqrd4v0	519	13	anti	anti	JJ
cord-017161-lcqrd4v0	519	14	-	-	JJ
cord-017161-lcqrd4v0	519	15	neutrophil	neutrophil	JJ
cord-017161-lcqrd4v0	519	16	cytoplasmic	cytoplasmic	JJ
cord-017161-lcqrd4v0	519	17	antibody	antibody	NN
cord-017161-lcqrd4v0	519	18	-	-	HYPH
cord-017161-lcqrd4v0	519	19	associated	associate	VBN
cord-017161-lcqrd4v0	519	20	systemic	systemic	JJ
cord-017161-lcqrd4v0	519	21	vasculitis	vasculitis	NN
cord-017161-lcqrd4v0	519	22	Successful	successful	JJ
cord-017161-lcqrd4v0	519	23	treatment	treatment	NN
cord-017161-lcqrd4v0	519	24	of	of	IN
cord-017161-lcqrd4v0	519	25	Behcet	Behcet	NNP
cord-017161-lcqrd4v0	519	26	's	's	POS
cord-017161-lcqrd4v0	519	27	disease	disease	NN
cord-017161-lcqrd4v0	519	28	with	with	IN
cord-017161-lcqrd4v0	519	29	lenalidomide	lenalidomide	NN