id author title date pages extension mime words sentences flesch summary cache txt cord-301160-7ik3iszp Lee, Kyung-Yil Kawasaki Disease: Laboratory Findings and an Immunopathogenesis on the Premise of a "Protein Homeostasis System" 2012-03-01 .txt text/plain 8967 436 43 Therefore, circulating immune cells, especially T cells, control the inflammation of the majority of the affected regions of KD patients without sequelae, but they also may be involved in the progression of the disease, such as in the case of CALs. Epidemiological and clinical data suggest that KD is an immunological reaction to infectious triggers occurring in genetically susceptible children. Many genetic studies in different countries have evaluated variants in candidate KD genes, and a number of variants, including inositol 1,4,5 triphosphate 3-kinase (ITPKC) and caspase-3, risk of CALs. For example, a severely affected patient who is persistently febrile for a week, showing constant low levels of platelet with high levels of AST and ALT in followup examination, may still not have reached the peak stage of inflammation, suggesting a higher possibility of more severe CALs. Laboratory findings are now mandatory for diagnosis of incomplete KD. ./cache/cord-301160-7ik3iszp.txt ./txt/cord-301160-7ik3iszp.txt