key: cord-279451-ax7n2ss5
authors: Semeraro, Federico; Scquizzato, Tommaso; Scapigliati, Andrea; Ristagno, Giuseppe; Gamberini, Lorenzo; Tartaglione, Marco; Dell’Arciprete, Oscar; Mora, Fabio; Cordenons, Fiorella; Del Giudice, Donatella; Picoco, Cosimo; Gordini, Giovanni
title: New Early Warning Score: off-label approach for Covid-19 outbreak patient deterioration in the community
date: 2020-04-20
journal: Resuscitation
DOI: 10.1016/j.resuscitation.2020.04.018
sha: 
doc_id: 279451
cord_uid: ax7n2ss5

nan

The spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in China at the end of 2019 is challenging most health systems worldwide 1 . In Italy, the first "wave" hit Lombardia on February 20, 2020, with such a high proportion of patients to impact substantially both admission to emergency department and intensive care treatment, and arising new concerns 2 . The Italian Ministry of Health and the National Health Service strongly recommended to all citizen to reduce access to healthcare facilities (e.g. emergency departments, ambulatory and elective surgery) for non-urgent reasons. Government also imposed several measures to contain the outbreak (e.g. closing of schools, limited access to public places, social isolation and preventive public health interventions). On April 9 th , at about forty eight days from the beginning of outbreak in Italy, the total number of cases have been 143.626, with 96.877 positive tests, and 28.470 discharged in healthy condition 3 . Unfortunately, the amount of death cases (18.279) has claimed Italy at the first place worldwide since the beginning of the outbreak. The Emilia Romagna is the second most affected Italian region after Lombardia. This condition leaded the local infectious disease task force to plan a change of paradigma basing prevention actions directly at home of the patients with infection. The aim is to assess patients at home to allow prescriptions of potential effective therapies (e.g. antiviral and chloroquine) when possible or intercepting those in borderline or warning conditions. Accordingly with this new approach, a research project was started on voluntary bases by a multidisciplinary teams (e.g. healthcare professionals, software developers, engineers, social manager etc.) with the aim to develop a web app based system to monitor deterioration of patients directly at home. The idea is based on the National Early Warning Score (NEWS) applied to a home context: by the use of an experimental app for smartphones, the in-built features of the device can measure directly parameters included in NEWS (e.g. accelerometer for respiratory rate and photo camera for heart rate measurements). This NEWS "off-label" approach in community setting with "homemade" measurements could facilitate self-calculation of the score, thus helping pre evaluation by healthcare professionals and recognising deterioration of patients at risk especially in conditions of overwhelming requests as during a pandemic. The hypothesis of early interception of deterioration could be useful to prevent potential increase in mortality that unfortunately did happen last month in Italy. We created a free open source platform called CovidUP19 4 ad hoc for citizens to increase awareness about potential deterioration in case of covid-19 infection. We invited all the international health system researchers to allocate time and resources on this innovative approach for potential "off label" application of NEWS in Covid-19 patients.

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