id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-317700-buzdfgyq	Beccuti, G.	A COVID-19 pneumonia case report of autoimmune polyendocrine syndrome type 1 in Lombardy, Italy: letter to the editor	2020-06-09		.txt	text/plain	1534	72	36	Regarding Addison's disease, the ESE statement affirms that there is no evidence that patients with adrenal insufficiency are at increased risk of contracting COVID-19, and there are no reported data on the outcomes of COVID-19 infection in adrenal-insufficient individuals. A population-based, retrospective, open cohort study in the United Kingdom from 1995 to 2018 showed that the Addison's disease cohort, compared with matched controls, had a higher risk of infections of the lower respiratory [adjusted incidence rate ratio (aIRR) 2.11; 95% CI 1.64-2.69], urinary (aIRR 1.51; 95% CI 1.29-1.77), and gastrointestinal (aIRR 3.80; 95% CI 2.99-4.84) tracts, leading to increased use of antimicrobial agents in the primary care setting [6] . Another Swedish population-based, retrospective study from 1964 to 2004 reported increased mortality from infections in patients with autoimmune PAI (standardized mortality ratio 5.9; 95% CI 4.0-8.4) [8] . In Norway, a population-based, retrospective study from 1943 to 2005 reported an increase in mortality from infections associated with Addison's disease [10% among causes of death (95% CI 5.1-14.9) vs.	./cache/cord-317700-buzdfgyq.txt	./txt/cord-317700-buzdfgyq.txt