id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-304266-49e723rj	Barone-Adesi, Francesco	Investigating the Determinants of High Case-Fatality Rate for Coronavirus Disease 2019 in Italy	2020-04-16		.txt	text/plain	756	46	57	T he epidemiologic features of the recent pandemic of coronavirus disease 2019 (COVID-19) have been shown to relevantly vary among countries, 1 with substantial differences in terms of incidence, mortality, and case-fatality rate (CFR), a parameter whose crude estimation is obtained by dividing the number of deaths by the total number of cases. In particular, a substantially higher CFR for COVID-19 was reported for Italy compared with other countries, and several authors put forward different hypotheses to explain it. [2] [3] [4] Using data from China and Italy, 1 paper suggested that this phenomenon could be due to mainly 3 different factors 2 : (1) a diverse age distribution; (2) a different definition of COVID-19-related deaths; and (3) a countryspecific strategy in testing. On the other hand, we think that the Italian testing strategy could explain an important part of the observed difference in CFRs. The majority of patients who are currently tested in Italy have severe clinical symptoms that usually require hospitalization.	./cache/cord-304266-49e723rj.txt	./txt/cord-304266-49e723rj.txt