id author title date pages extension mime words sentences flesch summary cache txt cord-258431-8zgwj2fa Strafella, Claudia Analysis of ACE2 Genetic Variability among Populations Highlights a Possible Link with COVID-19-Related Neurological Complications 2020-07-03 .txt text/plain 4055 203 42 The eQTLs analysis located in and targeting ACE2 revealed a high distribution of eQTL variants in different brain tissues, suggesting a possible link between ACE2 genetic variability and the neurological complications in patients with COVID-19. The final goal of the study has been the research of variants potentially affecting ACE2 expression and function, which may contribute to SARS-Cov-2 spreading among worldwide populations, and may have a clinical significance regarding the clinical variability and outcome displayed by patients with COVID-19. The final goal of the study has been the research of variants potentially affecting ACE2 expression and function, which may contribute to SARS-Cov-2 spreading among worldwide populations, and may have a clinical significance regarding the clinical variability and outcome displayed by patients with COVID-19. Moreover, they found a higher allelic frequency of eQTL variants, which is associated with higher ACE2 expression in tissues, suggesting a different susceptibility or response to SARS-Cov-2 infection with respect to other populations under similar conditions [28] . ./cache/cord-258431-8zgwj2fa.txt ./txt/cord-258431-8zgwj2fa.txt