id	sid	tid	token	lemma	pos
cord-347000-zxytdb0b	1	1	key	key	JJ
cord-347000-zxytdb0b	1	2	:	:	:
cord-347000-zxytdb0b	1	3	cord-347000-zxytdb0b	cord-347000-zxytdb0b	NNS
cord-347000-zxytdb0b	1	4	authors	author	NNS
cord-347000-zxytdb0b	1	5	:	:	:
cord-347000-zxytdb0b	1	6	Foweraker	Foweraker	NNP
cord-347000-zxytdb0b	1	7	,	,	,
cord-347000-zxytdb0b	1	8	Juliet	Juliet	NNP
cord-347000-zxytdb0b	1	9	title	title	NN
cord-347000-zxytdb0b	1	10	:	:	:
cord-347000-zxytdb0b	2	1	Recent	recent	JJ
cord-347000-zxytdb0b	2	2	advances	advance	NNS
cord-347000-zxytdb0b	2	3	in	in	IN
cord-347000-zxytdb0b	2	4	the	the	DT
cord-347000-zxytdb0b	2	5	microbiology	microbiology	NN
cord-347000-zxytdb0b	2	6	of	of	IN
cord-347000-zxytdb0b	2	7	respiratory	respiratory	JJ
cord-347000-zxytdb0b	2	8	tract	tract	NN
cord-347000-zxytdb0b	2	9	infection	infection	NN
cord-347000-zxytdb0b	2	10	in	in	IN
cord-347000-zxytdb0b	2	11	cystic	cystic	JJ
cord-347000-zxytdb0b	2	12	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	2	13	date	date	NN
cord-347000-zxytdb0b	2	14	:	:	:
cord-347000-zxytdb0b	2	15	2009	2009	CD
cord-347000-zxytdb0b	2	16	-	-	SYM
cord-347000-zxytdb0b	2	17	01	01	CD
cord-347000-zxytdb0b	2	18	-	-	HYPH
cord-347000-zxytdb0b	2	19	20	20	CD
cord-347000-zxytdb0b	2	20	journal	journal	NN
cord-347000-zxytdb0b	2	21	:	:	:
cord-347000-zxytdb0b	3	1	Br	Br	NNP
cord-347000-zxytdb0b	3	2	Med	Med	NNP
cord-347000-zxytdb0b	3	3	Bull	Bull	NNP
cord-347000-zxytdb0b	3	4	DOI	DOI	NNP
cord-347000-zxytdb0b	3	5	:	:	:
cord-347000-zxytdb0b	4	1	10.1093	10.1093	CD
cord-347000-zxytdb0b	4	2	/	/	SYM
cord-347000-zxytdb0b	4	3	bmb	bmb	NNP
cord-347000-zxytdb0b	4	4	/	/	SYM
cord-347000-zxytdb0b	4	5	ldn050	ldn050	NNP
cord-347000-zxytdb0b	4	6	sha	sha	NNP
cord-347000-zxytdb0b	4	7	:	:	:
cord-347000-zxytdb0b	4	8	9d209ab3376e51cbc00442378d02f2538e6ecb95	9d209ab3376e51cbc00442378d02f2538e6ecb95	CD
cord-347000-zxytdb0b	4	9	doc_id	doc_id	CD
cord-347000-zxytdb0b	4	10	:	:	:
cord-347000-zxytdb0b	4	11	347000	347000	CD
cord-347000-zxytdb0b	4	12	cord_uid	cord_uid	NNS
cord-347000-zxytdb0b	4	13	:	:	:
cord-347000-zxytdb0b	4	14	zxytdb0b	zxytdb0b	CD
cord-347000-zxytdb0b	5	1	INTRODUCTION	introduction	NN
cord-347000-zxytdb0b	5	2	:	:	:
cord-347000-zxytdb0b	6	1	Infection	infection	NN
cord-347000-zxytdb0b	6	2	is	be	VBZ
cord-347000-zxytdb0b	6	3	a	a	DT
cord-347000-zxytdb0b	6	4	major	major	JJ
cord-347000-zxytdb0b	6	5	cause	cause	NN
cord-347000-zxytdb0b	6	6	of	of	IN
cord-347000-zxytdb0b	6	7	morbidity	morbidity	NN
cord-347000-zxytdb0b	6	8	and	and	CC
cord-347000-zxytdb0b	6	9	mortality	mortality	NN
cord-347000-zxytdb0b	6	10	in	in	IN
cord-347000-zxytdb0b	6	11	patients	patient	NNS
cord-347000-zxytdb0b	6	12	with	with	IN
cord-347000-zxytdb0b	6	13	cystic	cystic	JJ
cord-347000-zxytdb0b	6	14	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	6	15	(	(	-LRB-
cord-347000-zxytdb0b	6	16	CF	CF	NNP
cord-347000-zxytdb0b	6	17	)	)	-RRB-
cord-347000-zxytdb0b	6	18	.	.	.
cord-347000-zxytdb0b	7	1	Research	research	NN
cord-347000-zxytdb0b	7	2	on	on	IN
cord-347000-zxytdb0b	7	3	CF	cf	NN
cord-347000-zxytdb0b	7	4	infection	infection	NN
cord-347000-zxytdb0b	7	5	has	have	VBZ
cord-347000-zxytdb0b	7	6	highlighted	highlight	VBN
cord-347000-zxytdb0b	7	7	differences	difference	NNS
cord-347000-zxytdb0b	7	8	from	from	IN
cord-347000-zxytdb0b	7	9	other	other	JJ
cord-347000-zxytdb0b	7	10	respiratory	respiratory	JJ
cord-347000-zxytdb0b	7	11	infections	infection	NNS
cord-347000-zxytdb0b	7	12	—	—	:
cord-347000-zxytdb0b	7	13	both	both	CC
cord-347000-zxytdb0b	7	14	in	in	IN
cord-347000-zxytdb0b	7	15	the	the	DT
cord-347000-zxytdb0b	7	16	range	range	NN
cord-347000-zxytdb0b	7	17	and	and	CC
cord-347000-zxytdb0b	7	18	the	the	DT
cord-347000-zxytdb0b	7	19	nature	nature	NN
cord-347000-zxytdb0b	7	20	of	of	IN
cord-347000-zxytdb0b	7	21	the	the	DT
cord-347000-zxytdb0b	7	22	organisms	organism	NNS
cord-347000-zxytdb0b	7	23	—	—	:
cord-347000-zxytdb0b	7	24	especially	especially	RB
cord-347000-zxytdb0b	7	25	in	in	IN
cord-347000-zxytdb0b	7	26	chronic	chronic	JJ
cord-347000-zxytdb0b	7	27	infection	infection	NN
cord-347000-zxytdb0b	7	28	.	.	.
cord-347000-zxytdb0b	8	1	This	this	DT
cord-347000-zxytdb0b	8	2	is	be	VBZ
cord-347000-zxytdb0b	8	3	a	a	DT
cord-347000-zxytdb0b	8	4	rapidly	rapidly	RB
cord-347000-zxytdb0b	8	5	advancing	advance	VBG
cord-347000-zxytdb0b	8	6	field	field	NN
cord-347000-zxytdb0b	8	7	of	of	IN
cord-347000-zxytdb0b	8	8	microbiology	microbiology	NN
cord-347000-zxytdb0b	8	9	and	and	CC
cord-347000-zxytdb0b	8	10	is	be	VBZ
cord-347000-zxytdb0b	8	11	bringing	bring	VBG
cord-347000-zxytdb0b	8	12	insights	insight	NNS
cord-347000-zxytdb0b	8	13	into	into	IN
cord-347000-zxytdb0b	8	14	the	the	DT
cord-347000-zxytdb0b	8	15	complexity	complexity	NN
cord-347000-zxytdb0b	8	16	and	and	CC
cord-347000-zxytdb0b	8	17	adaptations	adaptation	NNS
cord-347000-zxytdb0b	8	18	of	of	IN
cord-347000-zxytdb0b	8	19	bacteria	bacteria	NNS
cord-347000-zxytdb0b	8	20	causing	cause	VBG
cord-347000-zxytdb0b	8	21	chronic	chronic	JJ
cord-347000-zxytdb0b	8	22	infection	infection	NN
cord-347000-zxytdb0b	8	23	in	in	IN
cord-347000-zxytdb0b	8	24	the	the	DT
cord-347000-zxytdb0b	8	25	respiratory	respiratory	JJ
cord-347000-zxytdb0b	8	26	tract	tract	NN
cord-347000-zxytdb0b	8	27	.	.	.
cord-347000-zxytdb0b	9	1	AREAS	area	NNS
cord-347000-zxytdb0b	9	2	OF	of	IN
cord-347000-zxytdb0b	9	3	AGREEMENT	agreement	NN
cord-347000-zxytdb0b	9	4	AND	and	CC
cord-347000-zxytdb0b	9	5	CONTROVERSY	controversy	NN
cord-347000-zxytdb0b	9	6	:	:	:
cord-347000-zxytdb0b	10	1	The	the	DT
cord-347000-zxytdb0b	10	2	epidemiology	epidemiology	NN
cord-347000-zxytdb0b	10	3	of	of	IN
cord-347000-zxytdb0b	10	4	some	some	DT
cord-347000-zxytdb0b	10	5	infections	infection	NNS
cord-347000-zxytdb0b	10	6	in	in	IN
cord-347000-zxytdb0b	10	7	CF	CF	NNP
cord-347000-zxytdb0b	10	8	has	have	VBZ
cord-347000-zxytdb0b	10	9	changed	change	VBN
cord-347000-zxytdb0b	10	10	,	,	,
cord-347000-zxytdb0b	10	11	with	with	IN
cord-347000-zxytdb0b	10	12	reduction	reduction	NN
cord-347000-zxytdb0b	10	13	in	in	IN
cord-347000-zxytdb0b	10	14	spread	spread	NN
cord-347000-zxytdb0b	10	15	of	of	IN
cord-347000-zxytdb0b	10	16	Burkholderia	Burkholderia	NNP
cord-347000-zxytdb0b	10	17	cenocepacia	cenocepacia	VBD
cord-347000-zxytdb0b	10	18	following	follow	VBG
cord-347000-zxytdb0b	10	19	patient	patient	JJ
cord-347000-zxytdb0b	10	20	segregation	segregation	NN
cord-347000-zxytdb0b	10	21	.	.	.
cord-347000-zxytdb0b	11	1	Conversely	conversely	RB
cord-347000-zxytdb0b	11	2	,	,	,
cord-347000-zxytdb0b	11	3	epidemic	epidemic	NN
cord-347000-zxytdb0b	11	4	strains	strain	NNS
cord-347000-zxytdb0b	11	5	of	of	IN
cord-347000-zxytdb0b	11	6	Pseudomonas	Pseudomonas	NNP
cord-347000-zxytdb0b	11	7	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	11	8	have	have	VBP
cord-347000-zxytdb0b	11	9	emerged	emerge	VBN
cord-347000-zxytdb0b	11	10	,	,	,
cord-347000-zxytdb0b	11	11	which	which	WDT
cord-347000-zxytdb0b	11	12	spread	spread	VBD
cord-347000-zxytdb0b	11	13	between	between	IN
cord-347000-zxytdb0b	11	14	patients	patient	NNS
cord-347000-zxytdb0b	11	15	;	;	:
cord-347000-zxytdb0b	11	16	previously	previously	RB
cord-347000-zxytdb0b	11	17	,	,	,
cord-347000-zxytdb0b	11	18	most	most	JJS
cord-347000-zxytdb0b	11	19	P.	p.	NN
cord-347000-zxytdb0b	11	20	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	11	21	strains	strain	NNS
cord-347000-zxytdb0b	11	22	were	be	VBD
cord-347000-zxytdb0b	11	23	patient	patient	JJ
cord-347000-zxytdb0b	11	24	-	-	HYPH
cord-347000-zxytdb0b	11	25	specific	specific	JJ
cord-347000-zxytdb0b	11	26	.	.	.
cord-347000-zxytdb0b	12	1	Studies	study	NNS
cord-347000-zxytdb0b	12	2	on	on	IN
cord-347000-zxytdb0b	12	3	hypermutators	hypermutator	NNS
cord-347000-zxytdb0b	12	4	,	,	,
cord-347000-zxytdb0b	12	5	quorum	quorum	VB
cord-347000-zxytdb0b	12	6	sensing	sensing	NN
cord-347000-zxytdb0b	12	7	,	,	,
cord-347000-zxytdb0b	12	8	biofilm	biofilm	NN
cord-347000-zxytdb0b	12	9	growth	growth	NN
cord-347000-zxytdb0b	12	10	and	and	CC
cord-347000-zxytdb0b	12	11	the	the	DT
cord-347000-zxytdb0b	12	12	development	development	NN
cord-347000-zxytdb0b	12	13	of	of	IN
cord-347000-zxytdb0b	12	14	molecular	molecular	JJ
cord-347000-zxytdb0b	12	15	identification	identification	NN
cord-347000-zxytdb0b	12	16	have	have	VBP
cord-347000-zxytdb0b	12	17	shed	shed	VBN
cord-347000-zxytdb0b	12	18	light	light	NN
cord-347000-zxytdb0b	12	19	on	on	IN
cord-347000-zxytdb0b	12	20	pathogenicity	pathogenicity	NN
cord-347000-zxytdb0b	12	21	,	,	,
cord-347000-zxytdb0b	12	22	microbial	microbial	JJ
cord-347000-zxytdb0b	12	23	adaptation	adaptation	NN
cord-347000-zxytdb0b	12	24	to	to	IN
cord-347000-zxytdb0b	12	25	the	the	DT
cord-347000-zxytdb0b	12	26	host	host	NN
cord-347000-zxytdb0b	12	27	and	and	CC
cord-347000-zxytdb0b	12	28	complexity	complexity	NN
cord-347000-zxytdb0b	12	29	of	of	IN
cord-347000-zxytdb0b	12	30	infection	infection	NN
cord-347000-zxytdb0b	12	31	in	in	IN
cord-347000-zxytdb0b	12	32	CF	CF	NNP
cord-347000-zxytdb0b	12	33	.	.	.
cord-347000-zxytdb0b	13	1	Non	non	JJ
cord-347000-zxytdb0b	13	2	-	-	JJ
cord-347000-zxytdb0b	13	3	tuberculous	tuberculous	JJ
cord-347000-zxytdb0b	13	4	mycobacteria	mycobacterium	NNS
cord-347000-zxytdb0b	13	5	are	be	VBP
cord-347000-zxytdb0b	13	6	emerging	emerge	VBG
cord-347000-zxytdb0b	13	7	pathogens	pathogen	NNS
cord-347000-zxytdb0b	13	8	in	in	IN
cord-347000-zxytdb0b	13	9	CF	cf	NN
cord-347000-zxytdb0b	13	10	;	;	:
cord-347000-zxytdb0b	13	11	however	however	RB
cord-347000-zxytdb0b	13	12	,	,	,
cord-347000-zxytdb0b	13	13	there	there	EX
cord-347000-zxytdb0b	13	14	is	be	VBZ
cord-347000-zxytdb0b	13	15	much	much	JJ
cord-347000-zxytdb0b	13	16	to	to	TO
cord-347000-zxytdb0b	13	17	learn	learn	VB
cord-347000-zxytdb0b	13	18	about	about	IN
cord-347000-zxytdb0b	13	19	pathogenicity	pathogenicity	NN
cord-347000-zxytdb0b	13	20	and	and	CC
cord-347000-zxytdb0b	13	21	treatment	treatment	NN
cord-347000-zxytdb0b	13	22	of	of	IN
cord-347000-zxytdb0b	13	23	these	these	DT
cord-347000-zxytdb0b	13	24	infections	infection	NNS
cord-347000-zxytdb0b	13	25	.	.	.
cord-347000-zxytdb0b	14	1	Species	specie	NNS
cord-347000-zxytdb0b	14	2	of	of	IN
cord-347000-zxytdb0b	14	3	aerobic	aerobic	JJ
cord-347000-zxytdb0b	14	4	and	and	CC
cord-347000-zxytdb0b	14	5	anaerobic	anaerobic	JJ
cord-347000-zxytdb0b	14	6	bacteria	bacteria	NNS
cord-347000-zxytdb0b	14	7	,	,	,
cord-347000-zxytdb0b	14	8	more	more	RBR
cord-347000-zxytdb0b	14	9	commonly	commonly	RB
cord-347000-zxytdb0b	14	10	encountered	encounter	VBN
cord-347000-zxytdb0b	14	11	in	in	IN
cord-347000-zxytdb0b	14	12	the	the	DT
cord-347000-zxytdb0b	14	13	upper	upper	JJ
cord-347000-zxytdb0b	14	14	tract	tract	NN
cord-347000-zxytdb0b	14	15	,	,	,
cord-347000-zxytdb0b	14	16	are	be	VBP
cord-347000-zxytdb0b	14	17	found	find	VBN
cord-347000-zxytdb0b	14	18	in	in	IN
cord-347000-zxytdb0b	14	19	significant	significant	JJ
cord-347000-zxytdb0b	14	20	numbers	number	NNS
cord-347000-zxytdb0b	14	21	in	in	IN
cord-347000-zxytdb0b	14	22	CF	cf	NN
cord-347000-zxytdb0b	14	23	sputum	sputum	NN
cord-347000-zxytdb0b	14	24	.	.	.
cord-347000-zxytdb0b	15	1	The	the	DT
cord-347000-zxytdb0b	15	2	significance	significance	NN
cord-347000-zxytdb0b	15	3	of	of	IN
cord-347000-zxytdb0b	15	4	this	this	DT
cord-347000-zxytdb0b	15	5	is	be	VBZ
cord-347000-zxytdb0b	15	6	however	however	RB
cord-347000-zxytdb0b	15	7	under	under	IN
cord-347000-zxytdb0b	15	8	debate	debate	NN
cord-347000-zxytdb0b	15	9	.	.	.
cord-347000-zxytdb0b	16	1	Finally	finally	RB
cord-347000-zxytdb0b	16	2	,	,	,
cord-347000-zxytdb0b	16	3	although	although	IN
cord-347000-zxytdb0b	16	4	the	the	DT
cord-347000-zxytdb0b	16	5	clinical	clinical	JJ
cord-347000-zxytdb0b	16	6	relevance	relevance	NN
cord-347000-zxytdb0b	16	7	of	of	IN
cord-347000-zxytdb0b	16	8	conventional	conventional	JJ
cord-347000-zxytdb0b	16	9	antibiotic	antibiotic	JJ
cord-347000-zxytdb0b	16	10	susceptibility	susceptibility	NN
cord-347000-zxytdb0b	16	11	testing	testing	NN
cord-347000-zxytdb0b	16	12	for	for	IN
cord-347000-zxytdb0b	16	13	chronic	chronic	JJ
cord-347000-zxytdb0b	16	14	CF	CF	NNP
cord-347000-zxytdb0b	16	15	pathogens	pathogen	NNS
cord-347000-zxytdb0b	16	16	has	have	VBZ
cord-347000-zxytdb0b	16	17	been	be	VBN
cord-347000-zxytdb0b	16	18	questioned	question	VBN
cord-347000-zxytdb0b	16	19	,	,	,
cord-347000-zxytdb0b	16	20	there	there	EX
cord-347000-zxytdb0b	16	21	are	be	VBP
cord-347000-zxytdb0b	16	22	no	no	DT
cord-347000-zxytdb0b	16	23	clear	clear	JJ
cord-347000-zxytdb0b	16	24	alternatives	alternative	NNS
cord-347000-zxytdb0b	16	25	.	.	.
cord-347000-zxytdb0b	17	1	EMERGING	EMERGING	NNP
cord-347000-zxytdb0b	17	2	AREAS	area	NNS
cord-347000-zxytdb0b	17	3	FOR	for	IN
cord-347000-zxytdb0b	17	4	DEVELOPING	develop	VBG
cord-347000-zxytdb0b	17	5	RESEARCH	research	NN
cord-347000-zxytdb0b	17	6	:	:	:
cord-347000-zxytdb0b	18	1	Much	much	JJ
cord-347000-zxytdb0b	18	2	has	have	VBZ
cord-347000-zxytdb0b	18	3	been	be	VBN
cord-347000-zxytdb0b	18	4	learnt	learn	VBN
cord-347000-zxytdb0b	18	5	about	about	IN
cord-347000-zxytdb0b	18	6	pathogenicity	pathogenicity	NN
cord-347000-zxytdb0b	18	7	,	,	,
cord-347000-zxytdb0b	18	8	evolution	evolution	NN
cord-347000-zxytdb0b	18	9	of	of	IN
cord-347000-zxytdb0b	18	10	CF	cf	NN
cord-347000-zxytdb0b	18	11	pathogens	pathogen	NNS
cord-347000-zxytdb0b	18	12	and	and	CC
cord-347000-zxytdb0b	18	13	development	development	NN
cord-347000-zxytdb0b	18	14	of	of	IN
cord-347000-zxytdb0b	18	15	antibiotic	antibiotic	JJ
cord-347000-zxytdb0b	18	16	resistance	resistance	NN
cord-347000-zxytdb0b	18	17	.	.	.
cord-347000-zxytdb0b	19	1	The	the	DT
cord-347000-zxytdb0b	19	2	need	need	NN
cord-347000-zxytdb0b	19	3	is	be	VBZ
cord-347000-zxytdb0b	19	4	to	to	TO
cord-347000-zxytdb0b	19	5	focus	focus	VB
cord-347000-zxytdb0b	19	6	on	on	IN
cord-347000-zxytdb0b	19	7	clinical	clinical	JJ
cord-347000-zxytdb0b	19	8	relevance	relevance	NN
cord-347000-zxytdb0b	19	9	of	of	IN
cord-347000-zxytdb0b	19	10	these	these	DT
cord-347000-zxytdb0b	19	11	observations	observation	NNS
cord-347000-zxytdb0b	19	12	to	to	TO
cord-347000-zxytdb0b	19	13	improve	improve	VB
cord-347000-zxytdb0b	19	14	diagnosis	diagnosis	NN
cord-347000-zxytdb0b	19	15	,	,	,
cord-347000-zxytdb0b	19	16	prevention	prevention	NN
cord-347000-zxytdb0b	19	17	and	and	CC
cord-347000-zxytdb0b	19	18	treatment	treatment	NN
cord-347000-zxytdb0b	19	19	of	of	IN
cord-347000-zxytdb0b	19	20	CF	cf	NN
cord-347000-zxytdb0b	19	21	infection	infection	NN
cord-347000-zxytdb0b	19	22	.	.	.
cord-347000-zxytdb0b	20	1	Cystic	cystic	JJ
cord-347000-zxytdb0b	20	2	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	20	3	(	(	-LRB-
cord-347000-zxytdb0b	20	4	CF	CF	NNP
cord-347000-zxytdb0b	20	5	)	)	-RRB-
cord-347000-zxytdb0b	20	6	is	be	VBZ
cord-347000-zxytdb0b	20	7	an	an	DT
cord-347000-zxytdb0b	20	8	inherited	inherit	VBN
cord-347000-zxytdb0b	20	9	disorder	disorder	NN
cord-347000-zxytdb0b	20	10	due	due	IN
cord-347000-zxytdb0b	20	11	to	to	IN
cord-347000-zxytdb0b	20	12	a	a	DT
cord-347000-zxytdb0b	20	13	range	range	NN
cord-347000-zxytdb0b	20	14	of	of	IN
cord-347000-zxytdb0b	20	15	mutations	mutation	NNS
cord-347000-zxytdb0b	20	16	in	in	IN
cord-347000-zxytdb0b	20	17	the	the	DT
cord-347000-zxytdb0b	20	18	CF	CF	NNP
cord-347000-zxytdb0b	20	19	gene	gene	NN
cord-347000-zxytdb0b	20	20	affecting	affect	VBG
cord-347000-zxytdb0b	20	21	the	the	DT
cord-347000-zxytdb0b	20	22	cAMP	camp	NN
cord-347000-zxytdb0b	20	23	-	-	HYPH
cord-347000-zxytdb0b	20	24	regulated	regulate	VBN
cord-347000-zxytdb0b	20	25	chloride	chloride	NN
cord-347000-zxytdb0b	20	26	channel	channel	NN
cord-347000-zxytdb0b	20	27	(	(	-LRB-
cord-347000-zxytdb0b	20	28	CF	CF	NNP
cord-347000-zxytdb0b	20	29	transmembrane	transmembrane	NN
cord-347000-zxytdb0b	20	30	regulator	regulator	NN
cord-347000-zxytdb0b	20	31	or	or	CC
cord-347000-zxytdb0b	20	32	CFTR	CFTR	NNP
cord-347000-zxytdb0b	20	33	)	)	-RRB-
cord-347000-zxytdb0b	20	34	.	.	.
cord-347000-zxytdb0b	21	1	In	in	IN
cord-347000-zxytdb0b	21	2	the	the	DT
cord-347000-zxytdb0b	21	3	lungs	lung	NNS
cord-347000-zxytdb0b	21	4	,	,	,
cord-347000-zxytdb0b	21	5	this	this	DT
cord-347000-zxytdb0b	21	6	leads	lead	VBZ
cord-347000-zxytdb0b	21	7	to	to	IN
cord-347000-zxytdb0b	21	8	dehydration	dehydration	NN
cord-347000-zxytdb0b	21	9	of	of	IN
cord-347000-zxytdb0b	21	10	the	the	DT
cord-347000-zxytdb0b	21	11	peri	peri	NN
cord-347000-zxytdb0b	21	12	-	-	HYPH
cord-347000-zxytdb0b	21	13	ciliary	ciliary	NN
cord-347000-zxytdb0b	21	14	layer	layer	NN
cord-347000-zxytdb0b	21	15	such	such	JJ
cord-347000-zxytdb0b	21	16	that	that	IN
cord-347000-zxytdb0b	21	17	the	the	DT
cord-347000-zxytdb0b	21	18	mucociliary	mucociliary	JJ
cord-347000-zxytdb0b	21	19	escalator	escalator	NN
cord-347000-zxytdb0b	21	20	can	can	MD
cord-347000-zxytdb0b	21	21	not	not	RB
cord-347000-zxytdb0b	21	22	perform	perform	VB
cord-347000-zxytdb0b	21	23	its	-PRON-	PRP$
cord-347000-zxytdb0b	21	24	function	function	NN
cord-347000-zxytdb0b	21	25	of	of	IN
cord-347000-zxytdb0b	21	26	clearing	clearing	NN
cord-347000-zxytdb0b	21	27	particles	particle	NNS
cord-347000-zxytdb0b	21	28	(	(	-LRB-
cord-347000-zxytdb0b	21	29	including	include	VBG
cord-347000-zxytdb0b	21	30	microorganisms	microorganism	NNS
cord-347000-zxytdb0b	21	31	)	)	-RRB-
cord-347000-zxytdb0b	21	32	from	from	IN
cord-347000-zxytdb0b	21	33	the	the	DT
cord-347000-zxytdb0b	21	34	airways	airway	NNS
cord-347000-zxytdb0b	21	35	.	.	.
cord-347000-zxytdb0b	22	1	Patients	patient	NNS
cord-347000-zxytdb0b	22	2	develop	develop	VBP
cord-347000-zxytdb0b	22	3	acute	acute	JJ
cord-347000-zxytdb0b	22	4	and	and	CC
cord-347000-zxytdb0b	22	5	later	later	JJ
cord-347000-zxytdb0b	22	6	chronic	chronic	JJ
cord-347000-zxytdb0b	22	7	respiratory	respiratory	JJ
cord-347000-zxytdb0b	22	8	infection	infection	NN
cord-347000-zxytdb0b	22	9	leading	lead	VBG
cord-347000-zxytdb0b	22	10	to	to	IN
cord-347000-zxytdb0b	22	11	a	a	DT
cord-347000-zxytdb0b	22	12	cycle	cycle	NN
cord-347000-zxytdb0b	22	13	of	of	IN
cord-347000-zxytdb0b	22	14	further	further	JJ
cord-347000-zxytdb0b	22	15	damage	damage	NN
cord-347000-zxytdb0b	22	16	and	and	CC
cord-347000-zxytdb0b	22	17	less	less	JJR
cord-347000-zxytdb0b	22	18	ability	ability	NN
cord-347000-zxytdb0b	22	19	to	to	TO
cord-347000-zxytdb0b	22	20	clear	clear	VB
cord-347000-zxytdb0b	22	21	infection	infection	NN
cord-347000-zxytdb0b	22	22	.	.	.
cord-347000-zxytdb0b	23	1	The	the	DT
cord-347000-zxytdb0b	23	2	range	range	NN
cord-347000-zxytdb0b	23	3	of	of	IN
cord-347000-zxytdb0b	23	4	micro	micro	JJ
cord-347000-zxytdb0b	23	5	-	-	HYPH
cord-347000-zxytdb0b	23	6	organisms	organism	NNS
cord-347000-zxytdb0b	23	7	causing	cause	VBG
cord-347000-zxytdb0b	23	8	infection	infection	NN
cord-347000-zxytdb0b	23	9	differs	differ	VBZ
cord-347000-zxytdb0b	23	10	from	from	IN
cord-347000-zxytdb0b	23	11	those	those	DT
cord-347000-zxytdb0b	23	12	in	in	IN
cord-347000-zxytdb0b	23	13	patients	patient	NNS
cord-347000-zxytdb0b	23	14	without	without	IN
cord-347000-zxytdb0b	23	15	CF	cf	NN
cord-347000-zxytdb0b	23	16	with	with	IN
cord-347000-zxytdb0b	23	17	the	the	DT
cord-347000-zxytdb0b	23	18	commonest	common	JJS
cord-347000-zxytdb0b	23	19	pathogens	pathogen	NNS
cord-347000-zxytdb0b	23	20	being	be	VBG
cord-347000-zxytdb0b	23	21	Staphylococcus	Staphylococcus	NNP
cord-347000-zxytdb0b	23	22	aureus	aureus	NN
cord-347000-zxytdb0b	23	23	and	and	CC
cord-347000-zxytdb0b	23	24	Pseudomonas	Pseudomonas	NNP
cord-347000-zxytdb0b	23	25	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	23	26	.	.	.
cord-347000-zxytdb0b	24	1	1	1	CD
cord-347000-zxytdb0b	24	2	,	,	,
cord-347000-zxytdb0b	24	3	2	2	CD
cord-347000-zxytdb0b	24	4	Antibiotics	antibiotic	NNS
cord-347000-zxytdb0b	24	5	are	be	VBP
cord-347000-zxytdb0b	24	6	used	use	VBN
cord-347000-zxytdb0b	24	7	to	to	TO
cord-347000-zxytdb0b	24	8	clear	clear	VB
cord-347000-zxytdb0b	24	9	early	early	JJ
cord-347000-zxytdb0b	24	10	infection	infection	NN
cord-347000-zxytdb0b	24	11	,	,	,
cord-347000-zxytdb0b	24	12	treat	treat	VB
cord-347000-zxytdb0b	24	13	acute	acute	JJ
cord-347000-zxytdb0b	24	14	exacerbations	exacerbation	NNS
cord-347000-zxytdb0b	24	15	of	of	IN
cord-347000-zxytdb0b	24	16	chronic	chronic	JJ
cord-347000-zxytdb0b	24	17	infection	infection	NN
cord-347000-zxytdb0b	24	18	and	and	CC
cord-347000-zxytdb0b	24	19	reduce	reduce	VB
cord-347000-zxytdb0b	24	20	the	the	DT
cord-347000-zxytdb0b	24	21	frequency	frequency	NN
cord-347000-zxytdb0b	24	22	of	of	IN
cord-347000-zxytdb0b	24	23	exacerbations	exacerbation	NNS
cord-347000-zxytdb0b	24	24	(	(	-LRB-
cord-347000-zxytdb0b	24	25	by	by	IN
cord-347000-zxytdb0b	24	26	use	use	NN
cord-347000-zxytdb0b	24	27	of	of	IN
cord-347000-zxytdb0b	24	28	long	long	JJ
cord-347000-zxytdb0b	24	29	-	-	HYPH
cord-347000-zxytdb0b	24	30	term	term	NN
cord-347000-zxytdb0b	24	31	systemic	systemic	JJ
cord-347000-zxytdb0b	24	32	or	or	CC
cord-347000-zxytdb0b	24	33	inhaled	inhale	VBN
cord-347000-zxytdb0b	24	34	drugs	drug	NNS
cord-347000-zxytdb0b	24	35	)	)	-RRB-
cord-347000-zxytdb0b	24	36	.	.	.
cord-347000-zxytdb0b	25	1	These	these	DT
cord-347000-zxytdb0b	25	2	treatments	treatment	NNS
cord-347000-zxytdb0b	25	3	have	have	VBP
cord-347000-zxytdb0b	25	4	had	have	VBN
cord-347000-zxytdb0b	25	5	a	a	DT
cord-347000-zxytdb0b	25	6	major	major	JJ
cord-347000-zxytdb0b	25	7	impact	impact	NN
cord-347000-zxytdb0b	25	8	on	on	IN
cord-347000-zxytdb0b	25	9	the	the	DT
cord-347000-zxytdb0b	25	10	quality	quality	NN
cord-347000-zxytdb0b	25	11	and	and	CC
cord-347000-zxytdb0b	25	12	survival	survival	NN
cord-347000-zxytdb0b	25	13	of	of	IN
cord-347000-zxytdb0b	25	14	patients	patient	NNS
cord-347000-zxytdb0b	25	15	with	with	IN
cord-347000-zxytdb0b	25	16	CF	CF	NNP
cord-347000-zxytdb0b	25	17	.	.	.
cord-347000-zxytdb0b	26	1	There	there	EX
cord-347000-zxytdb0b	26	2	are	be	VBP
cord-347000-zxytdb0b	26	3	still	still	RB
cord-347000-zxytdb0b	26	4	however	however	RB
cord-347000-zxytdb0b	26	5	questions	question	NNS
cord-347000-zxytdb0b	26	6	about	about	IN
cord-347000-zxytdb0b	26	7	the	the	DT
cord-347000-zxytdb0b	26	8	best	good	JJS
cord-347000-zxytdb0b	26	9	way	way	NN
cord-347000-zxytdb0b	26	10	to	to	TO
cord-347000-zxytdb0b	26	11	diagnose	diagnose	VB
cord-347000-zxytdb0b	26	12	infection	infection	NN
cord-347000-zxytdb0b	26	13	and	and	CC
cord-347000-zxytdb0b	26	14	the	the	DT
cord-347000-zxytdb0b	26	15	use	use	NN
cord-347000-zxytdb0b	26	16	of	of	IN
cord-347000-zxytdb0b	26	17	antibiotics	antibiotic	NNS
cord-347000-zxytdb0b	26	18	in	in	IN
cord-347000-zxytdb0b	26	19	patients	patient	NNS
cord-347000-zxytdb0b	26	20	who	who	WP
cord-347000-zxytdb0b	26	21	will	will	MD
cord-347000-zxytdb0b	26	22	need	need	VB
cord-347000-zxytdb0b	26	23	repeated	repeat	VBN
cord-347000-zxytdb0b	26	24	courses	course	NNS
cord-347000-zxytdb0b	26	25	during	during	IN
cord-347000-zxytdb0b	26	26	their	-PRON-	PRP$
cord-347000-zxytdb0b	26	27	lifetime	lifetime	NN
cord-347000-zxytdb0b	26	28	.	.	.
cord-347000-zxytdb0b	27	1	Bacteria	Bacteria	NNS
cord-347000-zxytdb0b	27	2	in	in	IN
cord-347000-zxytdb0b	27	3	chronic	chronic	JJ
cord-347000-zxytdb0b	27	4	infection	infection	NN
cord-347000-zxytdb0b	27	5	have	have	VBP
cord-347000-zxytdb0b	27	6	different	different	JJ
cord-347000-zxytdb0b	27	7	characteristics	characteristic	NNS
cord-347000-zxytdb0b	27	8	from	from	IN
cord-347000-zxytdb0b	27	9	those	those	DT
cord-347000-zxytdb0b	27	10	causing	cause	VBG
cord-347000-zxytdb0b	27	11	acute	acute	JJ
cord-347000-zxytdb0b	27	12	infection	infection	NN
cord-347000-zxytdb0b	27	13	,	,	,
cord-347000-zxytdb0b	27	14	including	include	VBG
cord-347000-zxytdb0b	27	15	atypical	atypical	JJ
cord-347000-zxytdb0b	27	16	phenotypes	phenotype	NNS
cord-347000-zxytdb0b	27	17	leading	lead	VBG
cord-347000-zxytdb0b	27	18	to	to	IN
cord-347000-zxytdb0b	27	19	difficulty	difficulty	NN
cord-347000-zxytdb0b	27	20	in	in	IN
cord-347000-zxytdb0b	27	21	identifying	identify	VBG
cord-347000-zxytdb0b	27	22	some	some	DT
cord-347000-zxytdb0b	27	23	species	specie	NNS
cord-347000-zxytdb0b	27	24	in	in	IN
cord-347000-zxytdb0b	27	25	the	the	DT
cord-347000-zxytdb0b	27	26	laboratory	laboratory	NN
cord-347000-zxytdb0b	27	27	.	.	.
cord-347000-zxytdb0b	28	1	Antibiotic	antibiotic	JJ
cord-347000-zxytdb0b	28	2	resistance	resistance	NN
cord-347000-zxytdb0b	28	3	-	-	,
cord-347000-zxytdb0b	28	4	both	both	CC
cord-347000-zxytdb0b	28	5	from	from	IN
cord-347000-zxytdb0b	28	6	infection	infection	NN
cord-347000-zxytdb0b	28	7	with	with	IN
cord-347000-zxytdb0b	28	8	innately	innately	RB
cord-347000-zxytdb0b	28	9	resistant	resistant	JJ
cord-347000-zxytdb0b	28	10	bacteria	bacteria	NNS
cord-347000-zxytdb0b	28	11	and	and	CC
cord-347000-zxytdb0b	28	12	also	also	RB
cord-347000-zxytdb0b	28	13	the	the	DT
cord-347000-zxytdb0b	28	14	development	development	NN
cord-347000-zxytdb0b	28	15	of	of	IN
cord-347000-zxytdb0b	28	16	multi	multi	JJ
cord-347000-zxytdb0b	28	17	-	-	JJ
cord-347000-zxytdb0b	28	18	resistant	resistant	JJ
cord-347000-zxytdb0b	28	19	strainsis	strainsis	NN
cord-347000-zxytdb0b	28	20	an	an	DT
cord-347000-zxytdb0b	28	21	increasing	increase	VBG
cord-347000-zxytdb0b	28	22	challenge	challenge	NN
cord-347000-zxytdb0b	28	23	to	to	IN
cord-347000-zxytdb0b	28	24	CF	CF	NNP
cord-347000-zxytdb0b	28	25	.	.	.
cord-347000-zxytdb0b	29	1	Although	although	IN
cord-347000-zxytdb0b	29	2	infection	infection	NN
cord-347000-zxytdb0b	29	3	remains	remain	VBZ
cord-347000-zxytdb0b	29	4	the	the	DT
cord-347000-zxytdb0b	29	5	main	main	JJ
cord-347000-zxytdb0b	29	6	cause	cause	NN
cord-347000-zxytdb0b	29	7	of	of	IN
cord-347000-zxytdb0b	29	8	morbidity	morbidity	NN
cord-347000-zxytdb0b	29	9	and	and	CC
cord-347000-zxytdb0b	29	10	mortality	mortality	NN
cord-347000-zxytdb0b	29	11	,	,	,
cord-347000-zxytdb0b	29	12	3	3	CD
cord-347000-zxytdb0b	29	13	recent	recent	JJ
cord-347000-zxytdb0b	29	14	advances	advance	NNS
cord-347000-zxytdb0b	29	15	in	in	IN
cord-347000-zxytdb0b	29	16	understanding	understand	VBG
cord-347000-zxytdb0b	29	17	the	the	DT
cord-347000-zxytdb0b	29	18	role	role	NN
cord-347000-zxytdb0b	29	19	of	of	IN
cord-347000-zxytdb0b	29	20	different	different	JJ
cord-347000-zxytdb0b	29	21	species	specie	NNS
cord-347000-zxytdb0b	29	22	and	and	CC
cord-347000-zxytdb0b	29	23	modes	mode	NNS
cord-347000-zxytdb0b	29	24	of	of	IN
cord-347000-zxytdb0b	29	25	pathogenicity	pathogenicity	NN
cord-347000-zxytdb0b	29	26	hold	hold	VB
cord-347000-zxytdb0b	29	27	much	much	JJ
cord-347000-zxytdb0b	29	28	promise	promise	NN
cord-347000-zxytdb0b	29	29	for	for	IN
cord-347000-zxytdb0b	29	30	improved	improved	JJ
cord-347000-zxytdb0b	29	31	treatments	treatment	NNS
cord-347000-zxytdb0b	29	32	.	.	.
cord-347000-zxytdb0b	30	1	This	this	DT
cord-347000-zxytdb0b	30	2	review	review	NN
cord-347000-zxytdb0b	30	3	will	will	MD
cord-347000-zxytdb0b	30	4	focus	focus	VB
cord-347000-zxytdb0b	30	5	on	on	IN
cord-347000-zxytdb0b	30	6	recent	recent	JJ
cord-347000-zxytdb0b	30	7	advances	advance	NNS
cord-347000-zxytdb0b	30	8	in	in	IN
cord-347000-zxytdb0b	30	9	CF	CF	NNP
cord-347000-zxytdb0b	30	10	microbiology	microbiology	NN
cord-347000-zxytdb0b	30	11	,	,	,
cord-347000-zxytdb0b	30	12	look	look	VB
cord-347000-zxytdb0b	30	13	at	at	IN
cord-347000-zxytdb0b	30	14	their	-PRON-	PRP$
cord-347000-zxytdb0b	30	15	relevance	relevance	NN
cord-347000-zxytdb0b	30	16	to	to	IN
cord-347000-zxytdb0b	30	17	the	the	DT
cord-347000-zxytdb0b	30	18	diagnosis	diagnosis	NN
cord-347000-zxytdb0b	30	19	and	and	CC
cord-347000-zxytdb0b	30	20	management	management	NN
cord-347000-zxytdb0b	30	21	of	of	IN
cord-347000-zxytdb0b	30	22	infection	infection	NN
cord-347000-zxytdb0b	30	23	and	and	CC
cord-347000-zxytdb0b	30	24	highlight	highlight	NN
cord-347000-zxytdb0b	30	25	areas	area	NNS
cord-347000-zxytdb0b	30	26	that	that	WDT
cord-347000-zxytdb0b	30	27	need	need	VBP
cord-347000-zxytdb0b	30	28	further	further	JJ
cord-347000-zxytdb0b	30	29	development	development	NN
cord-347000-zxytdb0b	30	30	.	.	.
cord-347000-zxytdb0b	31	1	Specific	specific	JJ
cord-347000-zxytdb0b	31	2	antibiotic	antibiotic	JJ
cord-347000-zxytdb0b	31	3	treatment	treatment	NN
cord-347000-zxytdb0b	31	4	strategies	strategy	NNS
cord-347000-zxytdb0b	31	5	or	or	CC
cord-347000-zxytdb0b	31	6	practical	practical	JJ
cord-347000-zxytdb0b	31	7	guidelines	guideline	NNS
cord-347000-zxytdb0b	31	8	for	for	IN
cord-347000-zxytdb0b	31	9	the	the	DT
cord-347000-zxytdb0b	31	10	diagnosis	diagnosis	NN
cord-347000-zxytdb0b	31	11	of	of	IN
cord-347000-zxytdb0b	31	12	infection	infection	NN
cord-347000-zxytdb0b	31	13	will	will	MD
cord-347000-zxytdb0b	31	14	not	not	RB
cord-347000-zxytdb0b	31	15	be	be	VB
cord-347000-zxytdb0b	31	16	discussed	discuss	VBN
cord-347000-zxytdb0b	31	17	here	here	RB
cord-347000-zxytdb0b	31	18	but	but	CC
cord-347000-zxytdb0b	31	19	are	be	VBP
cord-347000-zxytdb0b	31	20	well	well	RB
cord-347000-zxytdb0b	31	21	reviewed	review	VBN
cord-347000-zxytdb0b	31	22	elsewhere	elsewhere	RB
cord-347000-zxytdb0b	31	23	.	.	.
cord-347000-zxytdb0b	32	1	4	4	LS
cord-347000-zxytdb0b	32	2	,	,	,
cord-347000-zxytdb0b	32	3	5	5	CD
cord-347000-zxytdb0b	32	4	Staphylococcus	Staphylococcus	NNP
cord-347000-zxytdb0b	32	5	aureus	aureus	NN
cord-347000-zxytdb0b	32	6	Staphylococcus	Staphylococcus	NNP
cord-347000-zxytdb0b	32	7	aureus	aureus	NN
cord-347000-zxytdb0b	32	8	is	be	VBZ
cord-347000-zxytdb0b	32	9	the	the	DT
cord-347000-zxytdb0b	32	10	most	most	RBS
cord-347000-zxytdb0b	32	11	frequent	frequent	JJ
cord-347000-zxytdb0b	32	12	pathogen	pathogen	NN
cord-347000-zxytdb0b	32	13	in	in	IN
cord-347000-zxytdb0b	32	14	young	young	JJ
cord-347000-zxytdb0b	32	15	infants	infant	NNS
cord-347000-zxytdb0b	32	16	with	with	IN
cord-347000-zxytdb0b	32	17	CF	CF	NNP
cord-347000-zxytdb0b	32	18	,	,	,
cord-347000-zxytdb0b	32	19	but	but	CC
cord-347000-zxytdb0b	32	20	an	an	DT
cord-347000-zxytdb0b	32	21	uncommon	uncommon	JJ
cord-347000-zxytdb0b	32	22	cause	cause	NN
cord-347000-zxytdb0b	32	23	of	of	IN
cord-347000-zxytdb0b	32	24	lower	low	JJR
cord-347000-zxytdb0b	32	25	respiratory	respiratory	JJ
cord-347000-zxytdb0b	32	26	tract	tract	NN
cord-347000-zxytdb0b	32	27	infection	infection	NN
cord-347000-zxytdb0b	32	28	in	in	IN
cord-347000-zxytdb0b	32	29	patients	patient	NNS
cord-347000-zxytdb0b	32	30	without	without	IN
cord-347000-zxytdb0b	32	31	CF	CF	NNP
cord-347000-zxytdb0b	32	32	.	.	.
cord-347000-zxytdb0b	33	1	It	-PRON-	PRP
cord-347000-zxytdb0b	33	2	has	have	VBZ
cord-347000-zxytdb0b	33	3	been	be	VBN
cord-347000-zxytdb0b	33	4	found	find	VBN
cord-347000-zxytdb0b	33	5	in	in	IN
cord-347000-zxytdb0b	33	6	broncho	broncho	JJ
cord-347000-zxytdb0b	33	7	-	-	HYPH
cord-347000-zxytdb0b	33	8	alveolar	alveolar	NN
cord-347000-zxytdb0b	33	9	lavage	lavage	NN
cord-347000-zxytdb0b	33	10	(	(	-LRB-
cord-347000-zxytdb0b	33	11	BAL	BAL	NNP
cord-347000-zxytdb0b	33	12	)	)	-RRB-
cord-347000-zxytdb0b	33	13	fluid	fluid	NN
cord-347000-zxytdb0b	33	14	in	in	IN
cord-347000-zxytdb0b	33	15	30	30	CD
cord-347000-zxytdb0b	33	16	%	%	NN
cord-347000-zxytdb0b	33	17	of	of	IN
cord-347000-zxytdb0b	33	18	CF	cf	NN
cord-347000-zxytdb0b	33	19	children	child	NNS
cord-347000-zxytdb0b	33	20	of	of	IN
cord-347000-zxytdb0b	33	21	average	average	JJ
cord-347000-zxytdb0b	33	22	age	age	NN
cord-347000-zxytdb0b	33	23	of	of	IN
cord-347000-zxytdb0b	33	24	3	3	CD
cord-347000-zxytdb0b	33	25	months	month	NNS
cord-347000-zxytdb0b	33	26	6	6	CD
cord-347000-zxytdb0b	33	27	and	and	CC
cord-347000-zxytdb0b	33	28	often	often	RB
cord-347000-zxytdb0b	33	29	persists	persist	VBZ
cord-347000-zxytdb0b	33	30	despite	despite	IN
cord-347000-zxytdb0b	33	31	treatment	treatment	NN
cord-347000-zxytdb0b	33	32	.	.	.
cord-347000-zxytdb0b	34	1	7	7	CD
cord-347000-zxytdb0b	35	1	The	the	DT
cord-347000-zxytdb0b	35	2	use	use	NN
cord-347000-zxytdb0b	35	3	of	of	IN
cord-347000-zxytdb0b	35	4	anti	anti	JJ
cord-347000-zxytdb0b	35	5	-	-	JJ
cord-347000-zxytdb0b	35	6	staphylococcal	staphylococcal	JJ
cord-347000-zxytdb0b	35	7	antibiotics	antibiotic	NNS
cord-347000-zxytdb0b	35	8	has	have	VBZ
cord-347000-zxytdb0b	35	9	been	be	VBN
cord-347000-zxytdb0b	35	10	clinically	clinically	RB
cord-347000-zxytdb0b	35	11	effective	effective	JJ
cord-347000-zxytdb0b	35	12	but	but	CC
cord-347000-zxytdb0b	35	13	the	the	DT
cord-347000-zxytdb0b	35	14	role	role	NN
cord-347000-zxytdb0b	35	15	of	of	IN
cord-347000-zxytdb0b	35	16	long	long	JJ
cord-347000-zxytdb0b	35	17	-	-	HYPH
cord-347000-zxytdb0b	35	18	term	term	NN
cord-347000-zxytdb0b	35	19	prophylaxis	prophylaxis	NN
cord-347000-zxytdb0b	35	20	for	for	IN
cord-347000-zxytdb0b	35	21	S.	S.	NNP
cord-347000-zxytdb0b	35	22	aureus	aureus	NN
cord-347000-zxytdb0b	35	23	is	be	VBZ
cord-347000-zxytdb0b	35	24	uncertain	uncertain	JJ
cord-347000-zxytdb0b	35	25	.	.	.
cord-347000-zxytdb0b	36	1	8	8	CD
cord-347000-zxytdb0b	37	1	The	the	DT
cord-347000-zxytdb0b	37	2	small	small	JJ
cord-347000-zxytdb0b	37	3	-	-	HYPH
cord-347000-zxytdb0b	37	4	colony	colony	NN
cord-347000-zxytdb0b	37	5	variant	variant	NN
cord-347000-zxytdb0b	37	6	(	(	-LRB-
cord-347000-zxytdb0b	37	7	SCV	SCV	NNP
cord-347000-zxytdb0b	37	8	)	)	-RRB-
cord-347000-zxytdb0b	37	9	phenotype	phenotype	NN
cord-347000-zxytdb0b	37	10	of	of	IN
cord-347000-zxytdb0b	37	11	S.	S.	NNP
cord-347000-zxytdb0b	37	12	aureus	aureus	NN
cord-347000-zxytdb0b	37	13	is	be	VBZ
cord-347000-zxytdb0b	37	14	common	common	JJ
cord-347000-zxytdb0b	37	15	in	in	IN
cord-347000-zxytdb0b	37	16	CF	cf	NN
cord-347000-zxytdb0b	37	17	patients	patient	NNS
cord-347000-zxytdb0b	37	18	.	.	.
cord-347000-zxytdb0b	38	1	7	7	CD
cord-347000-zxytdb0b	39	1	These	these	DT
cord-347000-zxytdb0b	39	2	bacteria	bacteria	NNS
cord-347000-zxytdb0b	39	3	have	have	VBP
cord-347000-zxytdb0b	39	4	adaptations	adaptation	NNS
cord-347000-zxytdb0b	39	5	including	include	VBG
cord-347000-zxytdb0b	39	6	antibiotic	antibiotic	JJ
cord-347000-zxytdb0b	39	7	resistance	resistance	NN
cord-347000-zxytdb0b	39	8	and	and	CC
cord-347000-zxytdb0b	39	9	the	the	DT
cord-347000-zxytdb0b	39	10	ability	ability	NN
cord-347000-zxytdb0b	39	11	to	to	TO
cord-347000-zxytdb0b	39	12	survive	survive	VB
cord-347000-zxytdb0b	39	13	inside	inside	IN
cord-347000-zxytdb0b	39	14	host	host	NN
cord-347000-zxytdb0b	39	15	cells	cell	NNS
cord-347000-zxytdb0b	39	16	,	,	,
cord-347000-zxytdb0b	39	17	which	which	WDT
cord-347000-zxytdb0b	39	18	may	may	MD
cord-347000-zxytdb0b	39	19	contribute	contribute	VB
cord-347000-zxytdb0b	39	20	to	to	IN
cord-347000-zxytdb0b	39	21	persistence	persistence	NN
cord-347000-zxytdb0b	39	22	in	in	IN
cord-347000-zxytdb0b	39	23	the	the	DT
cord-347000-zxytdb0b	39	24	CF	CF	NNP
cord-347000-zxytdb0b	39	25	airways	airways	NNP
cord-347000-zxytdb0b	39	26	.	.	.
cord-347000-zxytdb0b	40	1	The	the	DT
cord-347000-zxytdb0b	40	2	colonies	colony	NNS
cord-347000-zxytdb0b	40	3	are	be	VBP
cord-347000-zxytdb0b	40	4	very	very	RB
cord-347000-zxytdb0b	40	5	small	small	JJ
cord-347000-zxytdb0b	40	6	,	,	,
cord-347000-zxytdb0b	40	7	non	non	JJ
cord-347000-zxytdb0b	40	8	-	-	JJ
cord-347000-zxytdb0b	40	9	pigmented	pigmented	JJ
cord-347000-zxytdb0b	40	10	and	and	CC
cord-347000-zxytdb0b	40	11	are	be	VBP
cord-347000-zxytdb0b	40	12	slow	slow	JJ
cord-347000-zxytdb0b	40	13	growing	growing	NN
cord-347000-zxytdb0b	40	14	,	,	,
cord-347000-zxytdb0b	40	15	so	so	RB
cord-347000-zxytdb0b	40	16	may	may	MD
cord-347000-zxytdb0b	40	17	be	be	VB
cord-347000-zxytdb0b	40	18	missed	miss	VBN
cord-347000-zxytdb0b	40	19	during	during	IN
cord-347000-zxytdb0b	40	20	routine	routine	JJ
cord-347000-zxytdb0b	40	21	culture	culture	NN
cord-347000-zxytdb0b	40	22	,	,	,
cord-347000-zxytdb0b	40	23	but	but	CC
cord-347000-zxytdb0b	40	24	the	the	DT
cord-347000-zxytdb0b	40	25	use	use	NN
cord-347000-zxytdb0b	40	26	of	of	IN
cord-347000-zxytdb0b	40	27	certain	certain	JJ
cord-347000-zxytdb0b	40	28	media	medium	NNS
cord-347000-zxytdb0b	40	29	may	may	MD
cord-347000-zxytdb0b	40	30	make	make	VB
cord-347000-zxytdb0b	40	31	them	-PRON-	PRP
cord-347000-zxytdb0b	40	32	easier	easy	JJR
cord-347000-zxytdb0b	40	33	to	to	TO
cord-347000-zxytdb0b	40	34	recognize	recognize	VB
cord-347000-zxytdb0b	40	35	.	.	.
cord-347000-zxytdb0b	41	1	The	the	DT
cord-347000-zxytdb0b	41	2	slow	slow	JJ
cord-347000-zxytdb0b	41	3	growth	growth	NN
cord-347000-zxytdb0b	41	4	makes	make	VBZ
cord-347000-zxytdb0b	41	5	identification	identification	NN
cord-347000-zxytdb0b	41	6	and	and	CC
cord-347000-zxytdb0b	41	7	susceptibility	susceptibility	NN
cord-347000-zxytdb0b	41	8	testing	testing	NN
cord-347000-zxytdb0b	41	9	in	in	IN
cord-347000-zxytdb0b	41	10	automated	automate	VBN
cord-347000-zxytdb0b	41	11	systems	system	NNS
cord-347000-zxytdb0b	41	12	unreliable	unreliable	JJ
cord-347000-zxytdb0b	41	13	.	.	.
cord-347000-zxytdb0b	42	1	Longitudinal	longitudinal	JJ
cord-347000-zxytdb0b	42	2	studies	study	NNS
cord-347000-zxytdb0b	42	3	have	have	VBP
cord-347000-zxytdb0b	42	4	shown	show	VBN
cord-347000-zxytdb0b	42	5	a	a	DT
cord-347000-zxytdb0b	42	6	significantly	significantly	RB
cord-347000-zxytdb0b	42	7	higher	high	JJR
cord-347000-zxytdb0b	42	8	rate	rate	NN
cord-347000-zxytdb0b	42	9	of	of	IN
cord-347000-zxytdb0b	42	10	genome	genome	NN
cord-347000-zxytdb0b	42	11	alterations	alteration	NNS
cord-347000-zxytdb0b	42	12	in	in	IN
cord-347000-zxytdb0b	42	13	persisting	persist	VBG
cord-347000-zxytdb0b	42	14	clones	clone	NNS
cord-347000-zxytdb0b	42	15	of	of	IN
cord-347000-zxytdb0b	42	16	S.	S.	NNP
cord-347000-zxytdb0b	42	17	aureus	aureus	NN
cord-347000-zxytdb0b	42	18	in	in	IN
cord-347000-zxytdb0b	42	19	CF	cf	NN
cord-347000-zxytdb0b	42	20	sputum	sputum	NN
cord-347000-zxytdb0b	42	21	than	than	IN
cord-347000-zxytdb0b	42	22	those	those	DT
cord-347000-zxytdb0b	42	23	in	in	IN
cord-347000-zxytdb0b	42	24	the	the	DT
cord-347000-zxytdb0b	42	25	nose	nose	NN
cord-347000-zxytdb0b	42	26	of	of	IN
cord-347000-zxytdb0b	42	27	healthy	healthy	JJ
cord-347000-zxytdb0b	42	28	individuals	individual	NNS
cord-347000-zxytdb0b	42	29	,	,	,
cord-347000-zxytdb0b	42	30	presumably	presumably	RB
cord-347000-zxytdb0b	42	31	in	in	IN
cord-347000-zxytdb0b	42	32	response	response	NN
cord-347000-zxytdb0b	42	33	to	to	IN
cord-347000-zxytdb0b	42	34	the	the	DT
cord-347000-zxytdb0b	42	35	selective	selective	JJ
cord-347000-zxytdb0b	42	36	pressures	pressure	NNS
cord-347000-zxytdb0b	42	37	of	of	IN
cord-347000-zxytdb0b	42	38	the	the	DT
cord-347000-zxytdb0b	42	39	host	host	NN
cord-347000-zxytdb0b	42	40	response	response	NN
cord-347000-zxytdb0b	42	41	and	and	CC
cord-347000-zxytdb0b	42	42	repeated	repeat	VBN
cord-347000-zxytdb0b	42	43	use	use	NN
cord-347000-zxytdb0b	42	44	of	of	IN
cord-347000-zxytdb0b	42	45	antibiotics	antibiotic	NNS
cord-347000-zxytdb0b	42	46	in	in	IN
cord-347000-zxytdb0b	42	47	CF	CF	NNP
cord-347000-zxytdb0b	42	48	.	.	.
cord-347000-zxytdb0b	43	1	9	9	CD
cord-347000-zxytdb0b	43	2	Potential	potential	JJ
cord-347000-zxytdb0b	43	3	mechanisms	mechanism	NNS
cord-347000-zxytdb0b	43	4	for	for	IN
cord-347000-zxytdb0b	43	5	genome	genome	NN
cord-347000-zxytdb0b	43	6	alteration	alteration	NN
cord-347000-zxytdb0b	43	7	are	be	VBP
cord-347000-zxytdb0b	43	8	bacteriophage	bacteriophage	NN
cord-347000-zxytdb0b	43	9	mobilization	mobilization	NN
cord-347000-zxytdb0b	43	10	and	and	CC
cord-347000-zxytdb0b	43	11	hypermutability	hypermutability	NN
cord-347000-zxytdb0b	43	12	.	.	.
cord-347000-zxytdb0b	44	1	Hypermutator	Hypermutator	NNP
cord-347000-zxytdb0b	44	2	bacteria	bacteria	NNS
cord-347000-zxytdb0b	44	3	have	have	VBP
cord-347000-zxytdb0b	44	4	mutations	mutation	NNS
cord-347000-zxytdb0b	44	5	in	in	IN
cord-347000-zxytdb0b	44	6	DNA	dna	NN
cord-347000-zxytdb0b	44	7	repair	repair	NN
cord-347000-zxytdb0b	44	8	or	or	CC
cord-347000-zxytdb0b	44	9	error	error	NN
cord-347000-zxytdb0b	44	10	avoidance	avoidance	NN
cord-347000-zxytdb0b	44	11	genes	gene	NNS
cord-347000-zxytdb0b	44	12	such	such	JJ
cord-347000-zxytdb0b	44	13	that	that	IN
cord-347000-zxytdb0b	44	14	the	the	DT
cord-347000-zxytdb0b	44	15	spontaneous	spontaneous	JJ
cord-347000-zxytdb0b	44	16	mutation	mutation	NN
cord-347000-zxytdb0b	44	17	rate	rate	NN
cord-347000-zxytdb0b	44	18	is	be	VBZ
cord-347000-zxytdb0b	44	19	raised	raise	VBN
cord-347000-zxytdb0b	44	20	.	.	.
cord-347000-zxytdb0b	45	1	Mutator	Mutator	NNP
cord-347000-zxytdb0b	45	2	strains	strain	NNS
cord-347000-zxytdb0b	45	3	of	of	IN
cord-347000-zxytdb0b	45	4	S.	S.	NNP
cord-347000-zxytdb0b	45	5	aureus	aureu	NNS
cord-347000-zxytdb0b	45	6	have	have	VBP
cord-347000-zxytdb0b	45	7	been	be	VBN
cord-347000-zxytdb0b	45	8	identified	identify	VBN
cord-347000-zxytdb0b	45	9	in	in	IN
cord-347000-zxytdb0b	45	10	CF	CF	NNP
cord-347000-zxytdb0b	45	11	,	,	,
cord-347000-zxytdb0b	45	12	some	some	DT
cord-347000-zxytdb0b	45	13	due	due	IN
cord-347000-zxytdb0b	45	14	to	to	IN
cord-347000-zxytdb0b	45	15	inactivation	inactivation	NN
cord-347000-zxytdb0b	45	16	of	of	IN
cord-347000-zxytdb0b	45	17	a	a	DT
cord-347000-zxytdb0b	45	18	DNA	dna	NN
cord-347000-zxytdb0b	45	19	mismatch	mismatch	NN
cord-347000-zxytdb0b	45	20	repair	repair	NN
cord-347000-zxytdb0b	45	21	gene	gene	NN
cord-347000-zxytdb0b	45	22	mutS.	mutS.	NNP
cord-347000-zxytdb0b	45	23	10	10	CD
cord-347000-zxytdb0b	46	1	Another	another	DT
cord-347000-zxytdb0b	46	2	mechanism	mechanism	NN
cord-347000-zxytdb0b	46	3	that	that	WDT
cord-347000-zxytdb0b	46	4	may	may	MD
cord-347000-zxytdb0b	46	5	help	help	VB
cord-347000-zxytdb0b	46	6	the	the	DT
cord-347000-zxytdb0b	46	7	long	long	JJ
cord-347000-zxytdb0b	46	8	-	-	HYPH
cord-347000-zxytdb0b	46	9	term	term	NN
cord-347000-zxytdb0b	46	10	survival	survival	NN
cord-347000-zxytdb0b	46	11	of	of	IN
cord-347000-zxytdb0b	46	12	S.	S.	NNP
cord-347000-zxytdb0b	46	13	aureus	aureus	NN
cord-347000-zxytdb0b	46	14	in	in	IN
cord-347000-zxytdb0b	46	15	the	the	DT
cord-347000-zxytdb0b	46	16	CF	cf	NN
cord-347000-zxytdb0b	46	17	lung	lung	NN
cord-347000-zxytdb0b	46	18	is	be	VBZ
cord-347000-zxytdb0b	46	19	the	the	DT
cord-347000-zxytdb0b	46	20	ability	ability	NN
cord-347000-zxytdb0b	46	21	to	to	TO
cord-347000-zxytdb0b	46	22	form	form	VB
cord-347000-zxytdb0b	46	23	biofilms	biofilm	NNS
cord-347000-zxytdb0b	46	24	.	.	.
cord-347000-zxytdb0b	47	1	This	this	DT
cord-347000-zxytdb0b	47	2	may	may	MD
cord-347000-zxytdb0b	47	3	be	be	VB
cord-347000-zxytdb0b	47	4	important	important	JJ
cord-347000-zxytdb0b	47	5	for	for	IN
cord-347000-zxytdb0b	47	6	infection	infection	NN
cord-347000-zxytdb0b	47	7	of	of	IN
cord-347000-zxytdb0b	47	8	medical	medical	JJ
cord-347000-zxytdb0b	47	9	devices	device	NNS
cord-347000-zxytdb0b	47	10	and	and	CC
cord-347000-zxytdb0b	47	11	prostheses	prosthesis	NNS
cord-347000-zxytdb0b	47	12	such	such	JJ
cord-347000-zxytdb0b	47	13	as	as	IN
cord-347000-zxytdb0b	47	14	artificial	artificial	JJ
cord-347000-zxytdb0b	47	15	heart	heart	NN
cord-347000-zxytdb0b	47	16	valves	valve	NNS
cord-347000-zxytdb0b	47	17	and	and	CC
cord-347000-zxytdb0b	47	18	orthopaedic	orthopaedic	JJ
cord-347000-zxytdb0b	47	19	implants	implant	NNS
cord-347000-zxytdb0b	47	20	.	.	.
cord-347000-zxytdb0b	48	1	The	the	DT
cord-347000-zxytdb0b	48	2	role	role	NN
cord-347000-zxytdb0b	48	3	of	of	IN
cord-347000-zxytdb0b	48	4	biofilms	biofilm	NNS
cord-347000-zxytdb0b	48	5	in	in	IN
cord-347000-zxytdb0b	48	6	CF	CF	NNP
cord-347000-zxytdb0b	48	7	is	be	VBZ
cord-347000-zxytdb0b	48	8	however	however	RB
cord-347000-zxytdb0b	48	9	unclear	unclear	JJ
cord-347000-zxytdb0b	48	10	and	and	CC
cord-347000-zxytdb0b	48	11	needs	need	VBZ
cord-347000-zxytdb0b	48	12	further	further	JJ
cord-347000-zxytdb0b	48	13	investigation	investigation	NN
cord-347000-zxytdb0b	48	14	.	.	.
cord-347000-zxytdb0b	49	1	The	the	DT
cord-347000-zxytdb0b	49	2	increase	increase	NN
cord-347000-zxytdb0b	49	3	in	in	IN
cord-347000-zxytdb0b	49	4	methicillin	methicillin	NN
cord-347000-zxytdb0b	49	5	-	-	HYPH
cord-347000-zxytdb0b	49	6	resistant	resistant	JJ
cord-347000-zxytdb0b	49	7	S.	S.	NNP
cord-347000-zxytdb0b	49	8	aureus	aureus	NN
cord-347000-zxytdb0b	49	9	(	(	-LRB-
cord-347000-zxytdb0b	49	10	MRSA	MRSA	NNP
cord-347000-zxytdb0b	49	11	)	)	-RRB-
cord-347000-zxytdb0b	49	12	in	in	IN
cord-347000-zxytdb0b	49	13	the	the	DT
cord-347000-zxytdb0b	49	14	general	general	JJ
cord-347000-zxytdb0b	49	15	population	population	NN
cord-347000-zxytdb0b	49	16	has	have	VBZ
cord-347000-zxytdb0b	49	17	been	be	VBN
cord-347000-zxytdb0b	49	18	a	a	DT
cord-347000-zxytdb0b	49	19	cause	cause	NN
cord-347000-zxytdb0b	49	20	of	of	IN
cord-347000-zxytdb0b	49	21	concern	concern	NN
cord-347000-zxytdb0b	49	22	in	in	IN
cord-347000-zxytdb0b	49	23	many	many	JJ
cord-347000-zxytdb0b	49	24	countries	country	NNS
cord-347000-zxytdb0b	49	25	.	.	.
cord-347000-zxytdb0b	50	1	This	this	DT
cord-347000-zxytdb0b	50	2	is	be	VBZ
cord-347000-zxytdb0b	50	3	not	not	RB
cord-347000-zxytdb0b	50	4	because	because	IN
cord-347000-zxytdb0b	50	5	these	these	DT
cord-347000-zxytdb0b	50	6	organisms	organism	NNS
cord-347000-zxytdb0b	50	7	are	be	VBP
cord-347000-zxytdb0b	50	8	necessarily	necessarily	RB
cord-347000-zxytdb0b	50	9	more	more	RBR
cord-347000-zxytdb0b	50	10	pathogenic	pathogenic	JJ
cord-347000-zxytdb0b	50	11	,	,	,
cord-347000-zxytdb0b	50	12	rather	rather	RB
cord-347000-zxytdb0b	50	13	than	than	IN
cord-347000-zxytdb0b	50	14	treatment	treatment	NN
cord-347000-zxytdb0b	50	15	options	option	NNS
cord-347000-zxytdb0b	50	16	are	be	VBP
cord-347000-zxytdb0b	50	17	limited	limited	JJ
cord-347000-zxytdb0b	50	18	.	.	.
cord-347000-zxytdb0b	51	1	The	the	DT
cord-347000-zxytdb0b	51	2	mechanism	mechanism	NN
cord-347000-zxytdb0b	51	3	of	of	IN
cord-347000-zxytdb0b	51	4	resistance	resistance	NN
cord-347000-zxytdb0b	51	5	to	to	IN
cord-347000-zxytdb0b	51	6	methicillin	methicillin	NN
cord-347000-zxytdb0b	51	7	confers	confer	VBZ
cord-347000-zxytdb0b	51	8	resistance	resistance	NN
cord-347000-zxytdb0b	51	9	to	to	IN
cord-347000-zxytdb0b	51	10	all	all	DT
cord-347000-zxytdb0b	51	11	b	b	NN
cord-347000-zxytdb0b	51	12	-	-	:
cord-347000-zxytdb0b	51	13	lactams	lactam	NNS
cord-347000-zxytdb0b	51	14	(	(	-LRB-
cord-347000-zxytdb0b	51	15	penicillins	penicillin	NNS
cord-347000-zxytdb0b	51	16	and	and	CC
cord-347000-zxytdb0b	51	17	cephalosporins	cephalosporin	NNS
cord-347000-zxytdb0b	51	18	)	)	-RRB-
cord-347000-zxytdb0b	51	19	and	and	CC
cord-347000-zxytdb0b	51	20	many	many	JJ
cord-347000-zxytdb0b	51	21	strains	strain	NNS
cord-347000-zxytdb0b	51	22	of	of	IN
cord-347000-zxytdb0b	51	23	MRSA	MRSA	NNP
cord-347000-zxytdb0b	51	24	have	have	VBP
cord-347000-zxytdb0b	51	25	also	also	RB
cord-347000-zxytdb0b	51	26	acquired	acquire	VBN
cord-347000-zxytdb0b	51	27	resistance	resistance	NN
cord-347000-zxytdb0b	51	28	to	to	IN
cord-347000-zxytdb0b	51	29	unrelated	unrelated	JJ
cord-347000-zxytdb0b	51	30	antibiotics	antibiotic	NNS
cord-347000-zxytdb0b	51	31	,	,	,
cord-347000-zxytdb0b	51	32	such	such	JJ
cord-347000-zxytdb0b	51	33	as	as	IN
cord-347000-zxytdb0b	51	34	quinolones	quinolone	NNS
cord-347000-zxytdb0b	51	35	and	and	CC
cord-347000-zxytdb0b	51	36	aminoglycosides	aminoglycoside	NNS
cord-347000-zxytdb0b	51	37	.	.	.
cord-347000-zxytdb0b	52	1	Major	major	JJ
cord-347000-zxytdb0b	52	2	attempts	attempt	NNS
cord-347000-zxytdb0b	52	3	are	be	VBP
cord-347000-zxytdb0b	52	4	being	be	VBG
cord-347000-zxytdb0b	52	5	made	make	VBN
cord-347000-zxytdb0b	52	6	to	to	TO
cord-347000-zxytdb0b	52	7	control	control	VB
cord-347000-zxytdb0b	52	8	the	the	DT
cord-347000-zxytdb0b	52	9	spread	spread	NN
cord-347000-zxytdb0b	52	10	of	of	IN
cord-347000-zxytdb0b	52	11	resistant	resistant	JJ
cord-347000-zxytdb0b	52	12	S.	S.	NNP
cord-347000-zxytdb0b	52	13	aureus	aureus	NN
cord-347000-zxytdb0b	52	14	,	,	,
cord-347000-zxytdb0b	52	15	11	11	CD
cord-347000-zxytdb0b	52	16	with	with	IN
cord-347000-zxytdb0b	52	17	some	some	DT
cord-347000-zxytdb0b	52	18	success	success	NN
cord-347000-zxytdb0b	52	19	in	in	IN
cord-347000-zxytdb0b	52	20	the	the	DT
cord-347000-zxytdb0b	52	21	UK	UK	NNP
cord-347000-zxytdb0b	52	22	.	.	.
cord-347000-zxytdb0b	53	1	However	however	RB
cord-347000-zxytdb0b	53	2	,	,	,
cord-347000-zxytdb0b	53	3	the	the	DT
cord-347000-zxytdb0b	53	4	prevalence	prevalence	NN
cord-347000-zxytdb0b	53	5	of	of	IN
cord-347000-zxytdb0b	53	6	MRSA	MRSA	NNP
cord-347000-zxytdb0b	53	7	in	in	IN
cord-347000-zxytdb0b	53	8	CF	CF	NNP
cord-347000-zxytdb0b	53	9	patients	patient	NNS
cord-347000-zxytdb0b	53	10	is	be	VBZ
cord-347000-zxytdb0b	53	11	increasing	increase	VBG
cord-347000-zxytdb0b	53	12	12	12	CD
cord-347000-zxytdb0b	53	13	and	and	CC
cord-347000-zxytdb0b	53	14	vancomycin	vancomycin	NN
cord-347000-zxytdb0b	53	15	-	-	HYPH
cord-347000-zxytdb0b	53	16	resistant	resistant	JJ
cord-347000-zxytdb0b	53	17	S.	S.	NNP
cord-347000-zxytdb0b	53	18	aureus	aureus	NN
cord-347000-zxytdb0b	53	19	,	,	,
cord-347000-zxytdb0b	53	20	although	although	IN
cord-347000-zxytdb0b	53	21	very	very	RB
cord-347000-zxytdb0b	53	22	rare	rare	JJ
cord-347000-zxytdb0b	53	23	,	,	,
cord-347000-zxytdb0b	53	24	are	be	VBP
cord-347000-zxytdb0b	53	25	being	be	VBG
cord-347000-zxytdb0b	53	26	seen	see	VBN
cord-347000-zxytdb0b	53	27	in	in	IN
cord-347000-zxytdb0b	53	28	non	non	JJ
cord-347000-zxytdb0b	53	29	-	-	JJ
cord-347000-zxytdb0b	53	30	CF	cf	JJ
cord-347000-zxytdb0b	53	31	patients	patient	NNS
cord-347000-zxytdb0b	53	32	.	.	.
cord-347000-zxytdb0b	54	1	Treatment	treatment	NN
cord-347000-zxytdb0b	54	2	alternatives	alternative	NNS
cord-347000-zxytdb0b	54	3	to	to	IN
cord-347000-zxytdb0b	54	4	the	the	DT
cord-347000-zxytdb0b	54	5	glycopeptides	glycopeptide	NNS
cord-347000-zxytdb0b	54	6	are	be	VBP
cord-347000-zxytdb0b	54	7	now	now	RB
cord-347000-zxytdb0b	54	8	available	available	JJ
cord-347000-zxytdb0b	54	9	,	,	,
cord-347000-zxytdb0b	54	10	but	but	CC
cord-347000-zxytdb0b	54	11	experience	experience	NN
cord-347000-zxytdb0b	54	12	with	with	IN
cord-347000-zxytdb0b	54	13	them	-PRON-	PRP
cord-347000-zxytdb0b	54	14	in	in	IN
cord-347000-zxytdb0b	54	15	CF	CF	NNP
cord-347000-zxytdb0b	54	16	is	be	VBZ
cord-347000-zxytdb0b	54	17	limited	limit	VBN
cord-347000-zxytdb0b	54	18	.	.	.
cord-347000-zxytdb0b	55	1	Several	several	JJ
cord-347000-zxytdb0b	55	2	clearance	clearance	NN
cord-347000-zxytdb0b	55	3	regimens	regimen	NNS
cord-347000-zxytdb0b	55	4	have	have	VBP
cord-347000-zxytdb0b	55	5	been	be	VBN
cord-347000-zxytdb0b	55	6	proposed	propose	VBN
cord-347000-zxytdb0b	55	7	,	,	,
cord-347000-zxytdb0b	55	8	some	some	DT
cord-347000-zxytdb0b	55	9	surprisingly	surprisingly	RB
cord-347000-zxytdb0b	55	10	successful	successful	JJ
cord-347000-zxytdb0b	55	11	(	(	-LRB-
cord-347000-zxytdb0b	55	12	up	up	IN
cord-347000-zxytdb0b	55	13	to	to	TO
cord-347000-zxytdb0b	55	14	94	94	CD
cord-347000-zxytdb0b	55	15	%	%	NN
cord-347000-zxytdb0b	55	16	)	)	-RRB-
cord-347000-zxytdb0b	55	17	.	.	.
cord-347000-zxytdb0b	56	1	13	13	CD
cord-347000-zxytdb0b	56	2	 	 	_SP
cord-347000-zxytdb0b	57	1	Non	Non	NNS
cord-347000-zxytdb0b	57	2	-	-	JJ
cord-347000-zxytdb0b	57	3	encapsulate	encapsulate	JJ
cord-347000-zxytdb0b	57	4	and	and	CC
cord-347000-zxytdb0b	57	5	non	non	JJ
cord-347000-zxytdb0b	57	6	-	-	JJ
cord-347000-zxytdb0b	57	7	type	type	JJ
cord-347000-zxytdb0b	57	8	B	b	NN
cord-347000-zxytdb0b	57	9	capsulate	capsulate	NN
cord-347000-zxytdb0b	57	10	Haemophilus	haemophilus	NN
cord-347000-zxytdb0b	57	11	influenzae	influenzae	NN
cord-347000-zxytdb0b	57	12	are	be	VBP
cord-347000-zxytdb0b	57	13	more	more	RBR
cord-347000-zxytdb0b	57	14	common	common	JJ
cord-347000-zxytdb0b	57	15	in	in	IN
cord-347000-zxytdb0b	57	16	infants	infant	NNS
cord-347000-zxytdb0b	57	17	and	and	CC
cord-347000-zxytdb0b	57	18	young	young	JJ
cord-347000-zxytdb0b	57	19	children	child	NNS
cord-347000-zxytdb0b	57	20	with	with	IN
cord-347000-zxytdb0b	57	21	CF	CF	NNP
cord-347000-zxytdb0b	57	22	than	than	IN
cord-347000-zxytdb0b	57	23	in	in	IN
cord-347000-zxytdb0b	57	24	older	old	JJR
cord-347000-zxytdb0b	57	25	patients	patient	NNS
cord-347000-zxytdb0b	57	26	.	.	.
cord-347000-zxytdb0b	58	1	There	there	EX
cord-347000-zxytdb0b	58	2	is	be	VBZ
cord-347000-zxytdb0b	58	3	little	little	JJ
cord-347000-zxytdb0b	58	4	information	information	NN
cord-347000-zxytdb0b	58	5	on	on	IN
cord-347000-zxytdb0b	58	6	the	the	DT
cord-347000-zxytdb0b	58	7	epidemiology	epidemiology	NN
cord-347000-zxytdb0b	58	8	of	of	IN
cord-347000-zxytdb0b	58	9	long	long	JJ
cord-347000-zxytdb0b	58	10	-	-	HYPH
cord-347000-zxytdb0b	58	11	term	term	NN
cord-347000-zxytdb0b	58	12	infection	infection	NN
cord-347000-zxytdb0b	58	13	with	with	IN
cord-347000-zxytdb0b	58	14	H.	H.	NNP
cord-347000-zxytdb0b	58	15	influenzae	influenzae	NN
cord-347000-zxytdb0b	58	16	in	in	IN
cord-347000-zxytdb0b	58	17	CF	CF	NNP
cord-347000-zxytdb0b	58	18	.	.	.
cord-347000-zxytdb0b	59	1	A	a	DT
cord-347000-zxytdb0b	59	2	recent	recent	JJ
cord-347000-zxytdb0b	59	3	study	study	NN
cord-347000-zxytdb0b	59	4	showed	show	VBD
cord-347000-zxytdb0b	59	5	that	that	IN
cord-347000-zxytdb0b	59	6	Infections	Infections	NNPS
cord-347000-zxytdb0b	59	7	in	in	IN
cord-347000-zxytdb0b	59	8	cystic	cystic	JJ
cord-347000-zxytdb0b	59	9	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	59	10	infection	infection	NN
cord-347000-zxytdb0b	59	11	was	be	VBD
cord-347000-zxytdb0b	59	12	a	a	DT
cord-347000-zxytdb0b	59	13	dynamic	dynamic	JJ
cord-347000-zxytdb0b	59	14	process	process	NN
cord-347000-zxytdb0b	59	15	with	with	IN
cord-347000-zxytdb0b	59	16	most	most	JJS
cord-347000-zxytdb0b	59	17	patients	patient	NNS
cord-347000-zxytdb0b	59	18	sequentially	sequentially	RB
cord-347000-zxytdb0b	59	19	infected	infect	VBN
cord-347000-zxytdb0b	59	20	with	with	IN
cord-347000-zxytdb0b	59	21	different	different	JJ
cord-347000-zxytdb0b	59	22	strains	strain	NNS
cord-347000-zxytdb0b	59	23	.	.	.
cord-347000-zxytdb0b	60	1	Repeated	repeat	VBN
cord-347000-zxytdb0b	60	2	isolation	isolation	NN
cord-347000-zxytdb0b	60	3	of	of	IN
cord-347000-zxytdb0b	60	4	the	the	DT
cord-347000-zxytdb0b	60	5	same	same	JJ
cord-347000-zxytdb0b	60	6	clone	clone	NN
cord-347000-zxytdb0b	60	7	was	be	VBD
cord-347000-zxytdb0b	60	8	only	only	RB
cord-347000-zxytdb0b	60	9	seen	see	VBN
cord-347000-zxytdb0b	60	10	in	in	IN
cord-347000-zxytdb0b	60	11	5	5	CD
cord-347000-zxytdb0b	60	12	of	of	IN
cord-347000-zxytdb0b	60	13	27	27	CD
cord-347000-zxytdb0b	60	14	CF	CF	NNP
cord-347000-zxytdb0b	60	15	patients	patient	NNS
cord-347000-zxytdb0b	60	16	.	.	.
cord-347000-zxytdb0b	61	1	14	14	CD
cord-347000-zxytdb0b	62	1	There	there	EX
cord-347000-zxytdb0b	62	2	was	be	VBD
cord-347000-zxytdb0b	62	3	an	an	DT
cord-347000-zxytdb0b	62	4	increase	increase	NN
cord-347000-zxytdb0b	62	5	in	in	IN
cord-347000-zxytdb0b	62	6	antibiotic	antibiotic	JJ
cord-347000-zxytdb0b	62	7	resistance	resistance	NN
cord-347000-zxytdb0b	62	8	over	over	IN
cord-347000-zxytdb0b	62	9	time	time	NN
cord-347000-zxytdb0b	62	10	,	,	,
cord-347000-zxytdb0b	62	11	with	with	IN
cord-347000-zxytdb0b	62	12	37	37	CD
cord-347000-zxytdb0b	62	13	%	%	NN
cord-347000-zxytdb0b	62	14	of	of	IN
cord-347000-zxytdb0b	62	15	patients	patient	NNS
cord-347000-zxytdb0b	62	16	infected	infect	VBN
cord-347000-zxytdb0b	62	17	with	with	IN
cord-347000-zxytdb0b	62	18	H.	h.	NN
cord-347000-zxytdb0b	62	19	influenzae	influenzae	NN
cord-347000-zxytdb0b	62	20	resistant	resistant	JJ
cord-347000-zxytdb0b	62	21	to	to	IN
cord-347000-zxytdb0b	62	22	two	two	CD
cord-347000-zxytdb0b	62	23	or	or	CC
cord-347000-zxytdb0b	62	24	more	more	JJR
cord-347000-zxytdb0b	62	25	antibiotic	antibiotic	JJ
cord-347000-zxytdb0b	62	26	classes	class	NNS
cord-347000-zxytdb0b	62	27	.	.	.
cord-347000-zxytdb0b	63	1	Resistance	resistance	NN
cord-347000-zxytdb0b	63	2	included	include	VBD
cord-347000-zxytdb0b	63	3	decreased	decrease	VBD
cord-347000-zxytdb0b	63	4	susceptibility	susceptibility	NN
cord-347000-zxytdb0b	63	5	to	to	IN
cord-347000-zxytdb0b	63	6	ciprofloxacin	ciprofloxacin	NN
cord-347000-zxytdb0b	63	7	,	,	,
cord-347000-zxytdb0b	63	8	which	which	WDT
cord-347000-zxytdb0b	63	9	is	be	VBZ
cord-347000-zxytdb0b	63	10	rarely	rarely	RB
cord-347000-zxytdb0b	63	11	seen	see	VBN
cord-347000-zxytdb0b	63	12	outside	outside	IN
cord-347000-zxytdb0b	63	13	CF	CF	NNP
cord-347000-zxytdb0b	63	14	.	.	.
cord-347000-zxytdb0b	64	1	One	one	CD
cord-347000-zxytdb0b	64	2	-	-	HYPH
cord-347000-zxytdb0b	64	3	third	third	NN
cord-347000-zxytdb0b	64	4	of	of	IN
cord-347000-zxytdb0b	64	5	patients	patient	NNS
cord-347000-zxytdb0b	64	6	had	have	VBD
cord-347000-zxytdb0b	64	7	hypermutable	hypermutable	JJ
cord-347000-zxytdb0b	64	8	strains	strain	NNS
cord-347000-zxytdb0b	64	9	.	.	.
cord-347000-zxytdb0b	65	1	In	in	IN
cord-347000-zxytdb0b	65	2	another	another	DT
cord-347000-zxytdb0b	65	3	CF	CF	NNP
cord-347000-zxytdb0b	65	4	study	study	NN
cord-347000-zxytdb0b	65	5	,	,	,
cord-347000-zxytdb0b	65	6	a	a	DT
cord-347000-zxytdb0b	65	7	hypermutable	hypermutable	JJ
cord-347000-zxytdb0b	65	8	H.	h.	NN
cord-347000-zxytdb0b	65	9	influenzae	influenzae	NN
cord-347000-zxytdb0b	65	10	was	be	VBD
cord-347000-zxytdb0b	65	11	associated	associate	VBN
cord-347000-zxytdb0b	65	12	with	with	IN
cord-347000-zxytdb0b	65	13	mutation	mutation	NN
cord-347000-zxytdb0b	65	14	in	in	IN
cord-347000-zxytdb0b	65	15	mutS.	mutS.	NNP
cord-347000-zxytdb0b	65	16	15	15	CD
cord-347000-zxytdb0b	65	17	Over	over	IN
cord-347000-zxytdb0b	65	18	11	11	CD
cord-347000-zxytdb0b	65	19	months	month	NNS
cord-347000-zxytdb0b	65	20	,	,	,
cord-347000-zxytdb0b	65	21	this	this	DT
cord-347000-zxytdb0b	65	22	organism	organism	NN
cord-347000-zxytdb0b	65	23	gradually	gradually	RB
cord-347000-zxytdb0b	65	24	became	become	VBD
cord-347000-zxytdb0b	65	25	resistant	resistant	JJ
cord-347000-zxytdb0b	65	26	to	to	IN
cord-347000-zxytdb0b	65	27	the	the	DT
cord-347000-zxytdb0b	65	28	antibiotics	antibiotic	NNS
cord-347000-zxytdb0b	65	29	used	use	VBN
cord-347000-zxytdb0b	65	30	to	to	TO
cord-347000-zxytdb0b	65	31	treat	treat	VB
cord-347000-zxytdb0b	65	32	the	the	DT
cord-347000-zxytdb0b	65	33	patient	patient	NN
cord-347000-zxytdb0b	65	34	.	.	.
cord-347000-zxytdb0b	66	1	Persistence	persistence	NN
cord-347000-zxytdb0b	66	2	of	of	IN
cord-347000-zxytdb0b	66	3	H.	H.	NNP
cord-347000-zxytdb0b	66	4	influenzae	influenzae	NN
cord-347000-zxytdb0b	66	5	may	may	MD
cord-347000-zxytdb0b	66	6	be	be	VB
cord-347000-zxytdb0b	66	7	linked	link	VBN
cord-347000-zxytdb0b	66	8	to	to	IN
cord-347000-zxytdb0b	66	9	ability	ability	NN
cord-347000-zxytdb0b	66	10	to	to	TO
cord-347000-zxytdb0b	66	11	form	form	VB
cord-347000-zxytdb0b	66	12	biofilms	biofilm	NNS
cord-347000-zxytdb0b	66	13	.	.	.
cord-347000-zxytdb0b	67	1	This	this	DT
cord-347000-zxytdb0b	67	2	was	be	VBD
cord-347000-zxytdb0b	67	3	shown	show	VBN
cord-347000-zxytdb0b	67	4	in	in	IN
cord-347000-zxytdb0b	67	5	otitis	otitis	NN
cord-347000-zxytdb0b	67	6	media	medium	NNS
cord-347000-zxytdb0b	67	7	in	in	IN
cord-347000-zxytdb0b	67	8	non	non	JJ
cord-347000-zxytdb0b	67	9	-	-	JJ
cord-347000-zxytdb0b	67	10	CF	cf	JJ
cord-347000-zxytdb0b	67	11	patients	patient	NNS
cord-347000-zxytdb0b	67	12	.	.	.
cord-347000-zxytdb0b	68	1	Structures	structure	NNS
cord-347000-zxytdb0b	68	2	consistent	consistent	JJ
cord-347000-zxytdb0b	68	3	with	with	IN
cord-347000-zxytdb0b	68	4	biofilms	biofilm	NNS
cord-347000-zxytdb0b	68	5	have	have	VBP
cord-347000-zxytdb0b	68	6	now	now	RB
cord-347000-zxytdb0b	68	7	been	be	VBN
cord-347000-zxytdb0b	68	8	observed	observe	VBN
cord-347000-zxytdb0b	68	9	in	in	IN
cord-347000-zxytdb0b	68	10	the	the	DT
cord-347000-zxytdb0b	68	11	BAL	bal	NN
cord-347000-zxytdb0b	68	12	of	of	IN
cord-347000-zxytdb0b	68	13	asymptomatic	asymptomatic	JJ
cord-347000-zxytdb0b	68	14	CF	CF	NNP
cord-347000-zxytdb0b	68	15	patients	patient	NNS
cord-347000-zxytdb0b	68	16	.	.	.
cord-347000-zxytdb0b	69	1	Clinical	clinical	JJ
cord-347000-zxytdb0b	69	2	concentrations	concentration	NNS
cord-347000-zxytdb0b	69	3	of	of	IN
cord-347000-zxytdb0b	69	4	azithromycin	azithromycin	NNS
cord-347000-zxytdb0b	69	5	have	have	VBP
cord-347000-zxytdb0b	69	6	been	be	VBN
cord-347000-zxytdb0b	69	7	shown	show	VBN
cord-347000-zxytdb0b	69	8	to	to	TO
cord-347000-zxytdb0b	69	9	inhibit	inhibit	VB
cord-347000-zxytdb0b	69	10	biofilm	biofilm	NN
cord-347000-zxytdb0b	69	11	formation	formation	NN
cord-347000-zxytdb0b	69	12	and	and	CC
cord-347000-zxytdb0b	69	13	reduce	reduce	VB
cord-347000-zxytdb0b	69	14	established	establish	VBN
cord-347000-zxytdb0b	69	15	biofilms	biofilm	NNS
cord-347000-zxytdb0b	69	16	of	of	IN
cord-347000-zxytdb0b	69	17	H.	h.	NN
cord-347000-zxytdb0b	69	18	influenzae	influenzae	NN
cord-347000-zxytdb0b	69	19	in	in	IN
cord-347000-zxytdb0b	69	20	vitro	vitro	FW
cord-347000-zxytdb0b	69	21	without	without	IN
cord-347000-zxytdb0b	69	22	affecting	affect	VBG
cord-347000-zxytdb0b	69	23	bacterial	bacterial	JJ
cord-347000-zxytdb0b	69	24	growth	growth	NN
cord-347000-zxytdb0b	69	25	.	.	.
cord-347000-zxytdb0b	70	1	16	16	CD
cord-347000-zxytdb0b	70	2	 	 	_SP
cord-347000-zxytdb0b	71	1	Although	although	IN
cord-347000-zxytdb0b	71	2	Streptococcus	Streptococcus	NNP
cord-347000-zxytdb0b	71	3	pneumoniae	pneumoniae	NN
cord-347000-zxytdb0b	71	4	is	be	VBZ
cord-347000-zxytdb0b	71	5	a	a	DT
cord-347000-zxytdb0b	71	6	common	common	JJ
cord-347000-zxytdb0b	71	7	respiratory	respiratory	JJ
cord-347000-zxytdb0b	71	8	tract	tract	NN
cord-347000-zxytdb0b	71	9	pathogen	pathogen	NN
cord-347000-zxytdb0b	71	10	,	,	,
cord-347000-zxytdb0b	71	11	it	-PRON-	PRP
cord-347000-zxytdb0b	71	12	is	be	VBZ
cord-347000-zxytdb0b	71	13	unusual	unusual	JJ
cord-347000-zxytdb0b	71	14	in	in	IN
cord-347000-zxytdb0b	71	15	CF	CF	NNP
cord-347000-zxytdb0b	71	16	.	.	.
cord-347000-zxytdb0b	72	1	Rates	rate	NNS
cord-347000-zxytdb0b	72	2	of	of	IN
cord-347000-zxytdb0b	72	3	colonization	colonization	NN
cord-347000-zxytdb0b	72	4	range	range	NN
cord-347000-zxytdb0b	72	5	from	from	IN
cord-347000-zxytdb0b	72	6	3	3	CD
cord-347000-zxytdb0b	72	7	to	to	IN
cord-347000-zxytdb0b	72	8	5	5	CD
cord-347000-zxytdb0b	72	9	%	%	NN
cord-347000-zxytdb0b	72	10	in	in	IN
cord-347000-zxytdb0b	72	11	different	different	JJ
cord-347000-zxytdb0b	72	12	series	series	NN
cord-347000-zxytdb0b	72	13	.	.	.
cord-347000-zxytdb0b	73	1	A	a	DT
cord-347000-zxytdb0b	73	2	recent	recent	JJ
cord-347000-zxytdb0b	73	3	study	study	NN
cord-347000-zxytdb0b	73	4	showed	show	VBD
cord-347000-zxytdb0b	73	5	multi	multi	JJ
cord-347000-zxytdb0b	73	6	-	-	NN
cord-347000-zxytdb0b	73	7	resistance	resistance	NN
cord-347000-zxytdb0b	73	8	and	and	CC
cord-347000-zxytdb0b	73	9	possible	possible	JJ
cord-347000-zxytdb0b	73	10	hypermutators	hypermutator	NNS
cord-347000-zxytdb0b	73	11	in	in	IN
cord-347000-zxytdb0b	73	12	isolates	isolate	NNS
cord-347000-zxytdb0b	73	13	from	from	IN
cord-347000-zxytdb0b	73	14	CF	CF	NNP
cord-347000-zxytdb0b	73	15	.	.	.
cord-347000-zxytdb0b	74	1	17	17	CD
cord-347000-zxytdb0b	74	2	Streptococcus	streptococcus	NN
cord-347000-zxytdb0b	74	3	pneumoniae	pneumoniae	NN
cord-347000-zxytdb0b	74	4	from	from	IN
cord-347000-zxytdb0b	74	5	CF	cf	NN
cord-347000-zxytdb0b	74	6	respiratory	respiratory	JJ
cord-347000-zxytdb0b	74	7	samples	sample	NNS
cord-347000-zxytdb0b	74	8	were	be	VBD
cord-347000-zxytdb0b	74	9	better	well	JJR
cord-347000-zxytdb0b	74	10	at	at	IN
cord-347000-zxytdb0b	74	11	producing	produce	VBG
cord-347000-zxytdb0b	74	12	biofilms	biofilm	NNS
cord-347000-zxytdb0b	74	13	in	in	IN
cord-347000-zxytdb0b	74	14	vitro	vitro	FW
cord-347000-zxytdb0b	74	15	than	than	IN
cord-347000-zxytdb0b	74	16	blood	blood	NN
cord-347000-zxytdb0b	74	17	culture	culture	NN
cord-347000-zxytdb0b	74	18	isolates	isolate	NNS
cord-347000-zxytdb0b	74	19	from	from	IN
cord-347000-zxytdb0b	74	20	non	non	JJ
cord-347000-zxytdb0b	74	21	-	-	JJ
cord-347000-zxytdb0b	74	22	CF	cf	JJ
cord-347000-zxytdb0b	74	23	patients	patient	NNS
cord-347000-zxytdb0b	74	24	,	,	,
cord-347000-zxytdb0b	74	25	18	18	CD
cord-347000-zxytdb0b	74	26	which	which	WDT
cord-347000-zxytdb0b	74	27	suggests	suggest	VBZ
cord-347000-zxytdb0b	74	28	that	that	IN
cord-347000-zxytdb0b	74	29	these	these	DT
cord-347000-zxytdb0b	74	30	organisms	organism	NNS
cord-347000-zxytdb0b	74	31	have	have	VBP
cord-347000-zxytdb0b	74	32	the	the	DT
cord-347000-zxytdb0b	74	33	ability	ability	NN
cord-347000-zxytdb0b	74	34	to	to	TO
cord-347000-zxytdb0b	74	35	persist	persist	VB
cord-347000-zxytdb0b	74	36	in	in	IN
cord-347000-zxytdb0b	74	37	the	the	DT
cord-347000-zxytdb0b	74	38	CF	cf	NN
cord-347000-zxytdb0b	74	39	lung	lung	NN
cord-347000-zxytdb0b	74	40	.	.	.
cord-347000-zxytdb0b	75	1	It	-PRON-	PRP
cord-347000-zxytdb0b	75	2	is	be	VBZ
cord-347000-zxytdb0b	75	3	still	still	RB
cord-347000-zxytdb0b	75	4	however	however	RB
cord-347000-zxytdb0b	75	5	unclear	unclear	JJ
cord-347000-zxytdb0b	75	6	whether	whether	IN
cord-347000-zxytdb0b	75	7	S.	S.	NNP
cord-347000-zxytdb0b	75	8	pneumoniae	pneumoniae	NN
cord-347000-zxytdb0b	75	9	acts	act	VBZ
cord-347000-zxytdb0b	75	10	as	as	IN
cord-347000-zxytdb0b	75	11	a	a	DT
cord-347000-zxytdb0b	75	12	harmless	harmless	JJ
cord-347000-zxytdb0b	75	13	commensal	commensal	NN
cord-347000-zxytdb0b	75	14	in	in	IN
cord-347000-zxytdb0b	75	15	CF	CF	NNP
cord-347000-zxytdb0b	75	16	or	or	CC
cord-347000-zxytdb0b	75	17	has	have	VBZ
cord-347000-zxytdb0b	75	18	a	a	DT
cord-347000-zxytdb0b	75	19	role	role	NN
cord-347000-zxytdb0b	75	20	in	in	IN
cord-347000-zxytdb0b	75	21	acute	acute	JJ
cord-347000-zxytdb0b	75	22	exacerbation	exacerbation	NN
cord-347000-zxytdb0b	75	23	or	or	CC
cord-347000-zxytdb0b	75	24	facilitating	facilitate	VBG
cord-347000-zxytdb0b	75	25	infection	infection	NN
cord-347000-zxytdb0b	75	26	with	with	IN
cord-347000-zxytdb0b	75	27	other	other	JJ
cord-347000-zxytdb0b	75	28	pathogens	pathogen	NNS
cord-347000-zxytdb0b	75	29	.	.	.
cord-347000-zxytdb0b	76	1	Pseudomonas	Pseudomonas	NNP
cord-347000-zxytdb0b	76	2	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	76	3	is	be	VBZ
cord-347000-zxytdb0b	76	4	the	the	DT
cord-347000-zxytdb0b	76	5	most	most	RBS
cord-347000-zxytdb0b	76	6	common	common	JJ
cord-347000-zxytdb0b	76	7	pathogen	pathogen	NN
cord-347000-zxytdb0b	76	8	cultured	culture	VBN
cord-347000-zxytdb0b	76	9	from	from	IN
cord-347000-zxytdb0b	76	10	CF	cf	NN
cord-347000-zxytdb0b	76	11	sputum	sputum	NN
cord-347000-zxytdb0b	76	12	.	.	.
cord-347000-zxytdb0b	77	1	It	-PRON-	PRP
cord-347000-zxytdb0b	77	2	may	may	MD
cord-347000-zxytdb0b	77	3	be	be	VB
cord-347000-zxytdb0b	77	4	seen	see	VBN
cord-347000-zxytdb0b	77	5	early	early	RB
cord-347000-zxytdb0b	77	6	in	in	IN
cord-347000-zxytdb0b	77	7	infancy	infancy	NN
cord-347000-zxytdb0b	77	8	and	and	CC
cord-347000-zxytdb0b	77	9	is	be	VBZ
cord-347000-zxytdb0b	77	10	often	often	RB
cord-347000-zxytdb0b	77	11	cultured	culture	VBN
cord-347000-zxytdb0b	77	12	intermittently	intermittently	RB
cord-347000-zxytdb0b	77	13	during	during	IN
cord-347000-zxytdb0b	77	14	childhood	childhood	NN
cord-347000-zxytdb0b	77	15	.	.	.
cord-347000-zxytdb0b	78	1	Eventually	eventually	RB
cord-347000-zxytdb0b	78	2	,	,	,
cord-347000-zxytdb0b	78	3	chronic	chronic	JJ
cord-347000-zxytdb0b	78	4	infection	infection	NN
cord-347000-zxytdb0b	78	5	develops	develop	VBZ
cord-347000-zxytdb0b	78	6	and	and	CC
cord-347000-zxytdb0b	78	7	this	this	DT
cord-347000-zxytdb0b	78	8	leads	lead	VBZ
cord-347000-zxytdb0b	78	9	to	to	IN
cord-347000-zxytdb0b	78	10	a	a	DT
cord-347000-zxytdb0b	78	11	faster	fast	JJR
cord-347000-zxytdb0b	78	12	decline	decline	NN
cord-347000-zxytdb0b	78	13	in	in	IN
cord-347000-zxytdb0b	78	14	lung	lung	NN
cord-347000-zxytdb0b	78	15	function	function	NN
cord-347000-zxytdb0b	78	16	.	.	.
cord-347000-zxytdb0b	79	1	The	the	DT
cord-347000-zxytdb0b	79	2	age	age	NN
cord-347000-zxytdb0b	79	3	at	at	IN
cord-347000-zxytdb0b	79	4	which	which	WDT
cord-347000-zxytdb0b	79	5	infection	infection	NN
cord-347000-zxytdb0b	79	6	becomes	become	VBZ
cord-347000-zxytdb0b	79	7	chronic	chronic	NN
cord-347000-zxytdb0b	79	8	has	have	VBZ
cord-347000-zxytdb0b	79	9	increased	increase	VBN
cord-347000-zxytdb0b	79	10	with	with	IN
cord-347000-zxytdb0b	79	11	better	well	JJR
cord-347000-zxytdb0b	79	12	treatment	treatment	NN
cord-347000-zxytdb0b	79	13	of	of	IN
cord-347000-zxytdb0b	79	14	CF	CF	NNP
cord-347000-zxytdb0b	79	15	.	.	.
cord-347000-zxytdb0b	80	1	This	this	DT
cord-347000-zxytdb0b	80	2	is	be	VBZ
cord-347000-zxytdb0b	80	3	particularly	particularly	RB
cord-347000-zxytdb0b	80	4	due	due	JJ
cord-347000-zxytdb0b	80	5	to	to	IN
cord-347000-zxytdb0b	80	6	the	the	DT
cord-347000-zxytdb0b	80	7	practice	practice	NN
cord-347000-zxytdb0b	80	8	of	of	IN
cord-347000-zxytdb0b	80	9	intense	intense	JJ
cord-347000-zxytdb0b	80	10	treatment	treatment	NN
cord-347000-zxytdb0b	80	11	with	with	IN
cord-347000-zxytdb0b	80	12	antipseudomonal	antipseudomonal	JJ
cord-347000-zxytdb0b	80	13	antibiotics	antibiotic	NNS
cord-347000-zxytdb0b	80	14	when	when	WRB
cord-347000-zxytdb0b	80	15	P.	P.	NNP
cord-347000-zxytdb0b	80	16	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	80	17	is	be	VBZ
cord-347000-zxytdb0b	80	18	first	first	RB
cord-347000-zxytdb0b	80	19	cultured	cultured	JJ
cord-347000-zxytdb0b	80	20	,	,	,
cord-347000-zxytdb0b	80	21	which	which	WDT
cord-347000-zxytdb0b	80	22	can	can	MD
cord-347000-zxytdb0b	80	23	delay	delay	VB
cord-347000-zxytdb0b	80	24	the	the	DT
cord-347000-zxytdb0b	80	25	onset	onset	NN
cord-347000-zxytdb0b	80	26	of	of	IN
cord-347000-zxytdb0b	80	27	chronic	chronic	JJ
cord-347000-zxytdb0b	80	28	infection	infection	NN
cord-347000-zxytdb0b	80	29	and	and	CC
cord-347000-zxytdb0b	80	30	increase	increase	VB
cord-347000-zxytdb0b	80	31	life	life	NN
cord-347000-zxytdb0b	80	32	expectancy	expectancy	NN
cord-347000-zxytdb0b	80	33	in	in	IN
cord-347000-zxytdb0b	80	34	CF	CF	NNP
cord-347000-zxytdb0b	80	35	.	.	.
cord-347000-zxytdb0b	81	1	The	the	DT
cord-347000-zxytdb0b	81	2	patient	patient	NN
cord-347000-zxytdb0b	81	3	may	may	MD
cord-347000-zxytdb0b	81	4	be	be	VB
cord-347000-zxytdb0b	81	5	clinically	clinically	RB
cord-347000-zxytdb0b	81	6	stable	stable	JJ
cord-347000-zxytdb0b	81	7	when	when	WRB
cord-347000-zxytdb0b	81	8	chronically	chronically	RB
cord-347000-zxytdb0b	81	9	infected	infect	VBN
cord-347000-zxytdb0b	81	10	with	with	IN
cord-347000-zxytdb0b	81	11	P.	p.	NN
cord-347000-zxytdb0b	81	12	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	81	13	but	but	CC
cord-347000-zxytdb0b	81	14	has	have	VBZ
cord-347000-zxytdb0b	81	15	repeated	repeat	VBN
cord-347000-zxytdb0b	81	16	episodes	episode	NNS
cord-347000-zxytdb0b	81	17	of	of	IN
cord-347000-zxytdb0b	81	18	acute	acute	JJ
cord-347000-zxytdb0b	81	19	exacerbation	exacerbation	NN
cord-347000-zxytdb0b	81	20	with	with	IN
cord-347000-zxytdb0b	81	21	increased	increase	VBN
cord-347000-zxytdb0b	81	22	breathlessness	breathlessness	NN
cord-347000-zxytdb0b	81	23	,	,	,
cord-347000-zxytdb0b	81	24	sputum	sputum	NN
cord-347000-zxytdb0b	81	25	production	production	NN
cord-347000-zxytdb0b	81	26	and	and	CC
cord-347000-zxytdb0b	81	27	feeling	feel	VBG
cord-347000-zxytdb0b	81	28	unwell	unwell	JJ
cord-347000-zxytdb0b	81	29	.	.	.
cord-347000-zxytdb0b	82	1	These	these	DT
cord-347000-zxytdb0b	82	2	exacerbations	exacerbation	NNS
cord-347000-zxytdb0b	82	3	are	be	VBP
cord-347000-zxytdb0b	82	4	also	also	RB
cord-347000-zxytdb0b	82	5	marked	mark	VBN
cord-347000-zxytdb0b	82	6	by	by	IN
cord-347000-zxytdb0b	82	7	a	a	DT
cord-347000-zxytdb0b	82	8	reduction	reduction	NN
cord-347000-zxytdb0b	82	9	in	in	IN
cord-347000-zxytdb0b	82	10	lung	lung	NN
cord-347000-zxytdb0b	82	11	function	function	NN
cord-347000-zxytdb0b	82	12	.	.	.
cord-347000-zxytdb0b	83	1	Exacerbations	exacerbation	NNS
cord-347000-zxytdb0b	83	2	are	be	VBP
cord-347000-zxytdb0b	83	3	generally	generally	RB
cord-347000-zxytdb0b	83	4	treated	treat	VBN
cord-347000-zxytdb0b	83	5	with	with	IN
cord-347000-zxytdb0b	83	6	a	a	DT
cord-347000-zxytdb0b	83	7	combination	combination	NN
cord-347000-zxytdb0b	83	8	of	of	IN
cord-347000-zxytdb0b	83	9	systemic	systemic	JJ
cord-347000-zxytdb0b	83	10	antibiotics	antibiotic	NNS
cord-347000-zxytdb0b	83	11	.	.	.
cord-347000-zxytdb0b	84	1	5	5	LS
cord-347000-zxytdb0b	85	1	Inhaled	inhale	VBN
cord-347000-zxytdb0b	85	2	antibiotics	antibiotic	NNS
cord-347000-zxytdb0b	85	3	,	,	,
cord-347000-zxytdb0b	85	4	most	most	RBS
cord-347000-zxytdb0b	85	5	commonly	commonly	RB
cord-347000-zxytdb0b	85	6	colistin	colistin	NNP
cord-347000-zxytdb0b	85	7	or	or	CC
cord-347000-zxytdb0b	85	8	tobramycin	tobramycin	NNS
cord-347000-zxytdb0b	85	9	,	,	,
cord-347000-zxytdb0b	85	10	can	can	MD
cord-347000-zxytdb0b	85	11	be	be	VB
cord-347000-zxytdb0b	85	12	used	use	VBN
cord-347000-zxytdb0b	85	13	to	to	TO
cord-347000-zxytdb0b	85	14	help	help	VB
cord-347000-zxytdb0b	85	15	clear	clear	JJ
cord-347000-zxytdb0b	85	16	early	early	JJ
cord-347000-zxytdb0b	85	17	infection	infection	NN
cord-347000-zxytdb0b	85	18	.	.	.
cord-347000-zxytdb0b	86	1	They	-PRON-	PRP
cord-347000-zxytdb0b	86	2	can	can	MD
cord-347000-zxytdb0b	86	3	be	be	VB
cord-347000-zxytdb0b	86	4	effective	effective	JJ
cord-347000-zxytdb0b	86	5	as	as	IN
cord-347000-zxytdb0b	86	6	long	long	JJ
cord-347000-zxytdb0b	86	7	-	-	HYPH
cord-347000-zxytdb0b	86	8	term	term	NN
cord-347000-zxytdb0b	86	9	prophylaxis	prophylaxis	NN
cord-347000-zxytdb0b	86	10	,	,	,
cord-347000-zxytdb0b	86	11	reducing	reduce	VBG
cord-347000-zxytdb0b	86	12	frequency	frequency	NN
cord-347000-zxytdb0b	86	13	of	of	IN
cord-347000-zxytdb0b	86	14	acute	acute	JJ
cord-347000-zxytdb0b	86	15	exacerbation	exacerbation	NN
cord-347000-zxytdb0b	86	16	once	once	IN
cord-347000-zxytdb0b	86	17	infection	infection	NN
cord-347000-zxytdb0b	86	18	is	be	VBZ
cord-347000-zxytdb0b	86	19	chronic	chronic	JJ
cord-347000-zxytdb0b	86	20	.	.	.
cord-347000-zxytdb0b	87	1	More	more	RBR
cord-347000-zxytdb0b	87	2	recently	recently	RB
cord-347000-zxytdb0b	87	3	,	,	,
cord-347000-zxytdb0b	87	4	long	long	JJ
cord-347000-zxytdb0b	87	5	-	-	HYPH
cord-347000-zxytdb0b	87	6	term	term	NN
cord-347000-zxytdb0b	87	7	azithromycin	azithromycin	NNP
cord-347000-zxytdb0b	87	8	prophylaxis	prophylaxis	NN
cord-347000-zxytdb0b	87	9	has	have	VBZ
cord-347000-zxytdb0b	87	10	been	be	VBN
cord-347000-zxytdb0b	87	11	used	use	VBN
cord-347000-zxytdb0b	87	12	in	in	IN
cord-347000-zxytdb0b	87	13	CF	CF	NNP
cord-347000-zxytdb0b	87	14	.	.	.
cord-347000-zxytdb0b	88	1	This	this	DT
cord-347000-zxytdb0b	88	2	followed	follow	VBN
cord-347000-zxytdb0b	88	3	experience	experience	NN
cord-347000-zxytdb0b	88	4	with	with	IN
cord-347000-zxytdb0b	88	5	treating	treat	VBG
cord-347000-zxytdb0b	88	6	diffuse	diffuse	JJ
cord-347000-zxytdb0b	88	7	pan	pan	NN
cord-347000-zxytdb0b	88	8	-	-	HYPH
cord-347000-zxytdb0b	88	9	bronchiolitis	bronchiolitis	NNP
cord-347000-zxytdb0b	88	10	,	,	,
cord-347000-zxytdb0b	88	11	a	a	DT
cord-347000-zxytdb0b	88	12	condition	condition	NN
cord-347000-zxytdb0b	88	13	described	describe	VBN
cord-347000-zxytdb0b	88	14	in	in	IN
cord-347000-zxytdb0b	88	15	Japan	Japan	NNP
cord-347000-zxytdb0b	88	16	that	that	WDT
cord-347000-zxytdb0b	88	17	also	also	RB
cord-347000-zxytdb0b	88	18	leads	lead	VBZ
cord-347000-zxytdb0b	88	19	to	to	IN
cord-347000-zxytdb0b	88	20	chronic	chronic	JJ
cord-347000-zxytdb0b	88	21	infection	infection	NN
cord-347000-zxytdb0b	88	22	with	with	IN
cord-347000-zxytdb0b	88	23	P.	P.	NNP
cord-347000-zxytdb0b	88	24	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	88	25	.	.	.
cord-347000-zxytdb0b	89	1	The	the	DT
cord-347000-zxytdb0b	89	2	benefit	benefit	NN
cord-347000-zxytdb0b	89	3	of	of	IN
cord-347000-zxytdb0b	89	4	long	long	JJ
cord-347000-zxytdb0b	89	5	-	-	HYPH
cord-347000-zxytdb0b	89	6	term	term	NN
cord-347000-zxytdb0b	89	7	oral	oral	JJ
cord-347000-zxytdb0b	89	8	azithromycin	azithromycin	NN
cord-347000-zxytdb0b	89	9	has	have	VBZ
cord-347000-zxytdb0b	89	10	been	be	VBN
cord-347000-zxytdb0b	89	11	shown	show	VBN
cord-347000-zxytdb0b	89	12	in	in	IN
cord-347000-zxytdb0b	89	13	CF	CF	NNP
cord-347000-zxytdb0b	89	14	,	,	,
cord-347000-zxytdb0b	89	15	19	19	CD
cord-347000-zxytdb0b	89	16	with	with	IN
cord-347000-zxytdb0b	89	17	fewer	few	JJR
cord-347000-zxytdb0b	89	18	exacerbations	exacerbation	NNS
cord-347000-zxytdb0b	89	19	,	,	,
cord-347000-zxytdb0b	89	20	better	well	JJR
cord-347000-zxytdb0b	89	21	lung	lung	NN
cord-347000-zxytdb0b	89	22	function	function	NN
cord-347000-zxytdb0b	89	23	and	and	CC
cord-347000-zxytdb0b	89	24	a	a	DT
cord-347000-zxytdb0b	89	25	reduction	reduction	NN
cord-347000-zxytdb0b	89	26	in	in	IN
cord-347000-zxytdb0b	89	27	inflammatory	inflammatory	JJ
cord-347000-zxytdb0b	89	28	markers	marker	NNS
cord-347000-zxytdb0b	89	29	.	.	.
cord-347000-zxytdb0b	90	1	Macrolide	macrolide	JJ
cord-347000-zxytdb0b	90	2	antibiotics	antibiotic	NNS
cord-347000-zxytdb0b	90	3	may	may	MD
cord-347000-zxytdb0b	90	4	act	act	VB
cord-347000-zxytdb0b	90	5	because	because	IN
cord-347000-zxytdb0b	90	6	of	of	IN
cord-347000-zxytdb0b	90	7	their	-PRON-	PRP$
cord-347000-zxytdb0b	90	8	anti	anti	JJ
cord-347000-zxytdb0b	90	9	-	-	JJ
cord-347000-zxytdb0b	90	10	inflammatory	inflammatory	JJ
cord-347000-zxytdb0b	90	11	activity	activity	NN
cord-347000-zxytdb0b	90	12	or	or	CC
cord-347000-zxytdb0b	90	13	by	by	IN
cord-347000-zxytdb0b	90	14	modifying	modify	VBG
cord-347000-zxytdb0b	90	15	the	the	DT
cord-347000-zxytdb0b	90	16	pathogenicity	pathogenicity	NN
cord-347000-zxytdb0b	90	17	of	of	IN
cord-347000-zxytdb0b	90	18	P.	P.	NNP
cord-347000-zxytdb0b	90	19	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	90	20	(	(	-LRB-
cord-347000-zxytdb0b	90	21	see	see	VB
cord-347000-zxytdb0b	90	22	below	below	RB
cord-347000-zxytdb0b	90	23	)	)	-RRB-
cord-347000-zxytdb0b	90	24	.	.	.
cord-347000-zxytdb0b	91	1	Early	early	JJ
cord-347000-zxytdb0b	91	2	epidemiological	epidemiological	JJ
cord-347000-zxytdb0b	91	3	studies	study	NNS
cord-347000-zxytdb0b	91	4	showed	show	VBD
cord-347000-zxytdb0b	91	5	that	that	IN
cord-347000-zxytdb0b	91	6	cross	cross	NN
cord-347000-zxytdb0b	91	7	-	-	NN
cord-347000-zxytdb0b	91	8	infection	infection	NN
cord-347000-zxytdb0b	91	9	with	with	IN
cord-347000-zxytdb0b	91	10	P.	P.	NNP
cord-347000-zxytdb0b	91	11	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	91	12	was	be	VBD
cord-347000-zxytdb0b	91	13	rare	rare	JJ
cord-347000-zxytdb0b	91	14	and	and	CC
cord-347000-zxytdb0b	91	15	that	that	IN
cord-347000-zxytdb0b	91	16	CF	cf	NN
cord-347000-zxytdb0b	91	17	patients	patient	NNS
cord-347000-zxytdb0b	91	18	were	be	VBD
cord-347000-zxytdb0b	91	19	infected	infect	VBN
cord-347000-zxytdb0b	91	20	with	with	IN
cord-347000-zxytdb0b	91	21	their	-PRON-	PRP$
cord-347000-zxytdb0b	91	22	own	own	JJ
cord-347000-zxytdb0b	91	23	unique	unique	JJ
cord-347000-zxytdb0b	91	24	strains	strain	NNS
cord-347000-zxytdb0b	91	25	presumably	presumably	RB
cord-347000-zxytdb0b	91	26	acquired	acquire	VBN
cord-347000-zxytdb0b	91	27	from	from	IN
cord-347000-zxytdb0b	91	28	the	the	DT
cord-347000-zxytdb0b	91	29	environment	environment	NN
cord-347000-zxytdb0b	91	30	.	.	.
cord-347000-zxytdb0b	92	1	Some	some	DT
cord-347000-zxytdb0b	92	2	siblings	sibling	NNS
cord-347000-zxytdb0b	92	3	did	do	VBD
cord-347000-zxytdb0b	92	4	have	have	VB
cord-347000-zxytdb0b	92	5	the	the	DT
cord-347000-zxytdb0b	92	6	same	same	JJ
cord-347000-zxytdb0b	92	7	strain	strain	NN
cord-347000-zxytdb0b	92	8	but	but	CC
cord-347000-zxytdb0b	92	9	it	-PRON-	PRP
cord-347000-zxytdb0b	92	10	was	be	VBD
cord-347000-zxytdb0b	92	11	unclear	unclear	JJ
cord-347000-zxytdb0b	92	12	if	if	IN
cord-347000-zxytdb0b	92	13	this	this	DT
cord-347000-zxytdb0b	92	14	was	be	VBD
cord-347000-zxytdb0b	92	15	due	due	JJ
cord-347000-zxytdb0b	92	16	to	to	IN
cord-347000-zxytdb0b	92	17	cross	cross	NN
cord-347000-zxytdb0b	92	18	-	-	NN
cord-347000-zxytdb0b	92	19	infection	infection	NN
cord-347000-zxytdb0b	92	20	or	or	CC
cord-347000-zxytdb0b	92	21	acquisition	acquisition	NN
cord-347000-zxytdb0b	92	22	from	from	IN
cord-347000-zxytdb0b	92	23	a	a	DT
cord-347000-zxytdb0b	92	24	common	common	JJ
cord-347000-zxytdb0b	92	25	source	source	NN
cord-347000-zxytdb0b	92	26	.	.	.
cord-347000-zxytdb0b	93	1	In	in	IN
cord-347000-zxytdb0b	93	2	contrast	contrast	NN
cord-347000-zxytdb0b	93	3	,	,	,
cord-347000-zxytdb0b	93	4	more	more	JJR
cord-347000-zxytdb0b	93	5	recent	recent	JJ
cord-347000-zxytdb0b	93	6	studies	study	NNS
cord-347000-zxytdb0b	93	7	revealed	reveal	VBD
cord-347000-zxytdb0b	93	8	the	the	DT
cord-347000-zxytdb0b	93	9	spread	spread	NN
cord-347000-zxytdb0b	93	10	of	of	IN
cord-347000-zxytdb0b	93	11	the	the	DT
cord-347000-zxytdb0b	93	12	so	so	RB
cord-347000-zxytdb0b	93	13	-	-	HYPH
cord-347000-zxytdb0b	93	14	called	call	VBN
cord-347000-zxytdb0b	93	15	epidemic	epidemic	NN
cord-347000-zxytdb0b	93	16	strains	strain	NNS
cord-347000-zxytdb0b	93	17	,	,	,
cord-347000-zxytdb0b	93	18	some	some	DT
cord-347000-zxytdb0b	93	19	of	of	IN
cord-347000-zxytdb0b	93	20	which	which	WDT
cord-347000-zxytdb0b	93	21	were	be	VBD
cord-347000-zxytdb0b	93	22	multi	multi	JJ
cord-347000-zxytdb0b	93	23	-	-	JJ
cord-347000-zxytdb0b	93	24	resistant	resistant	JJ
cord-347000-zxytdb0b	93	25	.	.	.
cord-347000-zxytdb0b	94	1	This	this	DT
cord-347000-zxytdb0b	94	2	would	would	MD
cord-347000-zxytdb0b	94	3	not	not	RB
cord-347000-zxytdb0b	94	4	necessarily	necessarily	RB
cord-347000-zxytdb0b	94	5	be	be	VB
cord-347000-zxytdb0b	94	6	a	a	DT
cord-347000-zxytdb0b	94	7	particular	particular	JJ
cord-347000-zxytdb0b	94	8	concern	concern	NN
cord-347000-zxytdb0b	94	9	except	except	IN
cord-347000-zxytdb0b	94	10	that	that	IN
cord-347000-zxytdb0b	94	11	some	some	DT
cord-347000-zxytdb0b	94	12	,	,	,
cord-347000-zxytdb0b	94	13	for	for	IN
cord-347000-zxytdb0b	94	14	example	example	NN
cord-347000-zxytdb0b	94	15	,	,	,
cord-347000-zxytdb0b	94	16	the	the	DT
cord-347000-zxytdb0b	94	17	Liverpool	Liverpool	NNP
cord-347000-zxytdb0b	94	18	Epidemic	Epidemic	NNP
cord-347000-zxytdb0b	94	19	Strain	Strain	NNP
cord-347000-zxytdb0b	94	20	(	(	-LRB-
cord-347000-zxytdb0b	94	21	LES	LES	NNP
cord-347000-zxytdb0b	94	22	)	)	-RRB-
cord-347000-zxytdb0b	94	23	,	,	,
cord-347000-zxytdb0b	94	24	may	may	MD
cord-347000-zxytdb0b	94	25	be	be	VB
cord-347000-zxytdb0b	94	26	more	more	RBR
cord-347000-zxytdb0b	94	27	pathogenic	pathogenic	JJ
cord-347000-zxytdb0b	94	28	and	and	CC
cord-347000-zxytdb0b	94	29	can	can	MD
cord-347000-zxytdb0b	94	30	superinfect	superinfect	VB
cord-347000-zxytdb0b	94	31	patients	patient	NNS
cord-347000-zxytdb0b	94	32	already	already	RB
cord-347000-zxytdb0b	94	33	colonized	colonize	VBN
cord-347000-zxytdb0b	94	34	with	with	IN
cord-347000-zxytdb0b	94	35	other	other	JJ
cord-347000-zxytdb0b	94	36	strains	strain	NNS
cord-347000-zxytdb0b	94	37	of	of	IN
cord-347000-zxytdb0b	94	38	P.	P.	NNP
cord-347000-zxytdb0b	94	39	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	94	40	.	.	.
cord-347000-zxytdb0b	95	1	Infected	infected	JJ
cord-347000-zxytdb0b	95	2	patients	patient	NNS
cord-347000-zxytdb0b	95	3	had	have	VBD
cord-347000-zxytdb0b	95	4	more	more	JJR
cord-347000-zxytdb0b	95	5	exacerbations	exacerbation	NNS
cord-347000-zxytdb0b	95	6	,	,	,
cord-347000-zxytdb0b	95	7	time	time	NN
cord-347000-zxytdb0b	95	8	in	in	IN
cord-347000-zxytdb0b	95	9	hospital	hospital	NN
cord-347000-zxytdb0b	95	10	and	and	CC
cord-347000-zxytdb0b	95	11	courses	course	NNS
cord-347000-zxytdb0b	95	12	of	of	IN
cord-347000-zxytdb0b	95	13	antibiotics	antibiotic	NNS
cord-347000-zxytdb0b	95	14	.	.	.
cord-347000-zxytdb0b	96	1	20	20	CD
cord-347000-zxytdb0b	97	1	Furthermore	furthermore	RB
cord-347000-zxytdb0b	97	2	,	,	,
cord-347000-zxytdb0b	97	3	when	when	WRB
cord-347000-zxytdb0b	97	4	patients	patient	NNS
cord-347000-zxytdb0b	97	5	were	be	VBD
cord-347000-zxytdb0b	97	6	first	first	RB
cord-347000-zxytdb0b	97	7	infected	infect	VBN
cord-347000-zxytdb0b	97	8	with	with	IN
cord-347000-zxytdb0b	97	9	multiresistant	multiresistant	JJ
cord-347000-zxytdb0b	97	10	epidemic	epidemic	NN
cord-347000-zxytdb0b	97	11	P.	P.	NNP
cord-347000-zxytdb0b	97	12	aeruginosa	aeruginosa	VBZ
cord-347000-zxytdb0b	97	13	early	early	JJ
cord-347000-zxytdb0b	97	14	aggressive	aggressive	JJ
cord-347000-zxytdb0b	97	15	treatment	treatment	NN
cord-347000-zxytdb0b	97	16	often	often	RB
cord-347000-zxytdb0b	97	17	failed	fail	VBD
cord-347000-zxytdb0b	97	18	.	.	.
cord-347000-zxytdb0b	98	1	21	21	CD
cord-347000-zxytdb0b	99	1	This	this	DT
cord-347000-zxytdb0b	99	2	led	lead	VBD
cord-347000-zxytdb0b	99	3	to	to	IN
cord-347000-zxytdb0b	99	4	a	a	DT
cord-347000-zxytdb0b	99	5	policy	policy	NN
cord-347000-zxytdb0b	99	6	in	in	IN
cord-347000-zxytdb0b	99	7	the	the	DT
cord-347000-zxytdb0b	99	8	UK	UK	NNP
cord-347000-zxytdb0b	99	9	of	of	IN
cord-347000-zxytdb0b	99	10	segregating	segregate	VBG
cord-347000-zxytdb0b	99	11	patients	patient	NNS
cord-347000-zxytdb0b	99	12	with	with	IN
cord-347000-zxytdb0b	99	13	epidemic	epidemic	NN
cord-347000-zxytdb0b	99	14	strains	strain	NNS
cord-347000-zxytdb0b	99	15	.	.	.
cord-347000-zxytdb0b	100	1	The	the	DT
cord-347000-zxytdb0b	100	2	LES	LES	NNP
cord-347000-zxytdb0b	100	3	genome	genome	NN
cord-347000-zxytdb0b	100	4	was	be	VBD
cord-347000-zxytdb0b	100	5	recently	recently	RB
cord-347000-zxytdb0b	100	6	sequenced	sequence	VBN
cord-347000-zxytdb0b	100	7	and	and	CC
cord-347000-zxytdb0b	100	8	work	work	NN
cord-347000-zxytdb0b	100	9	is	be	VBZ
cord-347000-zxytdb0b	100	10	progressing	progress	VBG
cord-347000-zxytdb0b	100	11	to	to	TO
cord-347000-zxytdb0b	100	12	determine	determine	VB
cord-347000-zxytdb0b	100	13	the	the	DT
cord-347000-zxytdb0b	100	14	basis	basis	NN
cord-347000-zxytdb0b	100	15	of	of	IN
cord-347000-zxytdb0b	100	16	transmissibility	transmissibility	NN
cord-347000-zxytdb0b	100	17	and	and	CC
cord-347000-zxytdb0b	100	18	enhanced	enhanced	JJ
cord-347000-zxytdb0b	100	19	pathogenicity	pathogenicity	NN
cord-347000-zxytdb0b	100	20	.	.	.
cord-347000-zxytdb0b	101	1	Most	Most	JJS
cord-347000-zxytdb0b	101	2	strains	strain	NNS
cord-347000-zxytdb0b	101	3	of	of	IN
cord-347000-zxytdb0b	101	4	LES	LES	NNP
cord-347000-zxytdb0b	101	5	are	be	VBP
cord-347000-zxytdb0b	101	6	hyper	hyper	JJ
cord-347000-zxytdb0b	101	7	-	-	NNS
cord-347000-zxytdb0b	101	8	producers	producer	NNS
cord-347000-zxytdb0b	101	9	of	of	IN
cord-347000-zxytdb0b	101	10	pyocyanin	pyocyanin	NNP
cord-347000-zxytdb0b	101	11	.	.	.
cord-347000-zxytdb0b	102	1	This	this	DT
cord-347000-zxytdb0b	102	2	is	be	VBZ
cord-347000-zxytdb0b	102	3	a	a	DT
cord-347000-zxytdb0b	102	4	putative	putative	JJ
cord-347000-zxytdb0b	102	5	pathogenicity	pathogenicity	NN
cord-347000-zxytdb0b	102	6	factor	factor	NN
cord-347000-zxytdb0b	102	7	with	with	IN
cord-347000-zxytdb0b	102	8	effects	effect	NNS
cord-347000-zxytdb0b	102	9	including	include	VBG
cord-347000-zxytdb0b	102	10	reduced	reduce	VBN
cord-347000-zxytdb0b	102	11	beating	beating	NN
cord-347000-zxytdb0b	102	12	of	of	IN
cord-347000-zxytdb0b	102	13	respiratory	respiratory	JJ
cord-347000-zxytdb0b	102	14	epithelium	epithelium	NN
cord-347000-zxytdb0b	102	15	cilia	cilium	NNS
cord-347000-zxytdb0b	102	16	and	and	CC
cord-347000-zxytdb0b	102	17	induction	induction	NN
cord-347000-zxytdb0b	102	18	neutrophil	neutrophil	NN
cord-347000-zxytdb0b	102	19	apoptosis	apoptosis	NN
cord-347000-zxytdb0b	102	20	,	,	,
cord-347000-zxytdb0b	102	21	and	and	CC
cord-347000-zxytdb0b	102	22	is	be	VBZ
cord-347000-zxytdb0b	102	23	regulated	regulate	VBN
cord-347000-zxytdb0b	102	24	by	by	IN
cord-347000-zxytdb0b	102	25	quorum	quorum	NN
cord-347000-zxytdb0b	102	26	sensing	sensing	NN
cord-347000-zxytdb0b	102	27	(	(	-LRB-
cord-347000-zxytdb0b	102	28	QS	QS	NNP
cord-347000-zxytdb0b	102	29	)	)	-RRB-
cord-347000-zxytdb0b	102	30	(	(	-LRB-
cord-347000-zxytdb0b	102	31	lasA	lasA	NNP
cord-347000-zxytdb0b	102	32	)	)	-RRB-
cord-347000-zxytdb0b	102	33	.	.	.
cord-347000-zxytdb0b	103	1	22	22	CD
cord-347000-zxytdb0b	103	2	QS	QS	NNP
cord-347000-zxytdb0b	103	3	systems	system	NNS
cord-347000-zxytdb0b	103	4	have	have	VBP
cord-347000-zxytdb0b	103	5	been	be	VBN
cord-347000-zxytdb0b	103	6	extensively	extensively	RB
cord-347000-zxytdb0b	103	7	studied	study	VBN
cord-347000-zxytdb0b	103	8	in	in	IN
cord-347000-zxytdb0b	103	9	P.	P.	NNP
cord-347000-zxytdb0b	103	10	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	103	11	.	.	.
cord-347000-zxytdb0b	104	1	Molecular	molecular	JJ
cord-347000-zxytdb0b	104	2	signals	signal	NNS
cord-347000-zxytdb0b	104	3	allow	allow	VBP
cord-347000-zxytdb0b	104	4	communication	communication	NN
cord-347000-zxytdb0b	104	5	between	between	IN
cord-347000-zxytdb0b	104	6	bacteria	bacteria	NNS
cord-347000-zxytdb0b	104	7	.	.	.
cord-347000-zxytdb0b	105	1	23	23	CD
cord-347000-zxytdb0b	106	1	They	-PRON-	PRP
cord-347000-zxytdb0b	106	2	are	be	VBP
cord-347000-zxytdb0b	106	3	secreted	secrete	VBN
cord-347000-zxytdb0b	106	4	and	and	CC
cord-347000-zxytdb0b	106	5	at	at	IN
cord-347000-zxytdb0b	106	6	a	a	DT
cord-347000-zxytdb0b	106	7	certain	certain	JJ
cord-347000-zxytdb0b	106	8	concentration	concentration	NN
cord-347000-zxytdb0b	106	9	can	can	MD
cord-347000-zxytdb0b	106	10	trigger	trigger	VB
cord-347000-zxytdb0b	106	11	expression	expression	NN
cord-347000-zxytdb0b	106	12	of	of	IN
cord-347000-zxytdb0b	106	13	genes	gene	NNS
cord-347000-zxytdb0b	106	14	.	.	.
cord-347000-zxytdb0b	107	1	In	in	IN
cord-347000-zxytdb0b	107	2	P.	P.	NNP
cord-347000-zxytdb0b	107	3	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	107	4	,	,	,
cord-347000-zxytdb0b	107	5	these	these	DT
cord-347000-zxytdb0b	107	6	include	include	VBP
cord-347000-zxytdb0b	107	7	those	those	DT
cord-347000-zxytdb0b	107	8	that	that	DT
cord-347000-zxytdb0b	107	9	code	code	NN
cord-347000-zxytdb0b	107	10	for	for	IN
cord-347000-zxytdb0b	107	11	pathogenicity	pathogenicity	NN
cord-347000-zxytdb0b	107	12	factors	factor	NNS
cord-347000-zxytdb0b	107	13	,	,	,
cord-347000-zxytdb0b	107	14	biofilm	biofilm	NN
cord-347000-zxytdb0b	107	15	formation	formation	NN
cord-347000-zxytdb0b	107	16	and	and	CC
cord-347000-zxytdb0b	107	17	motility	motility	NN
cord-347000-zxytdb0b	107	18	.	.	.
cord-347000-zxytdb0b	108	1	It	-PRON-	PRP
cord-347000-zxytdb0b	108	2	is	be	VBZ
cord-347000-zxytdb0b	108	3	thought	think	VBN
cord-347000-zxytdb0b	108	4	that	that	IN
cord-347000-zxytdb0b	108	5	5	5	CD
cord-347000-zxytdb0b	108	6	%	%	NN
cord-347000-zxytdb0b	108	7	of	of	IN
cord-347000-zxytdb0b	108	8	genes	gene	NNS
cord-347000-zxytdb0b	108	9	in	in	IN
cord-347000-zxytdb0b	108	10	P.	P.	NNP
cord-347000-zxytdb0b	108	11	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	108	12	are	be	VBP
cord-347000-zxytdb0b	108	13	regulated	regulate	VBN
cord-347000-zxytdb0b	108	14	by	by	IN
cord-347000-zxytdb0b	108	15	QS	QS	NNP
cord-347000-zxytdb0b	108	16	and	and	CC
cord-347000-zxytdb0b	108	17	this	this	DT
cord-347000-zxytdb0b	108	18	mechanism	mechanism	NN
cord-347000-zxytdb0b	108	19	allows	allow	VBZ
cord-347000-zxytdb0b	108	20	precise	precise	JJ
cord-347000-zxytdb0b	108	21	regulation	regulation	NN
cord-347000-zxytdb0b	108	22	of	of	IN
cord-347000-zxytdb0b	108	23	genes	gene	NNS
cord-347000-zxytdb0b	108	24	in	in	IN
cord-347000-zxytdb0b	108	25	response	response	NN
cord-347000-zxytdb0b	108	26	to	to	IN
cord-347000-zxytdb0b	108	27	environmental	environmental	JJ
cord-347000-zxytdb0b	108	28	stimuli	stimulus	NNS
cord-347000-zxytdb0b	108	29	and	and	CC
cord-347000-zxytdb0b	108	30	cell	cell	NN
cord-347000-zxytdb0b	108	31	density	density	NN
cord-347000-zxytdb0b	108	32	.	.	.
cord-347000-zxytdb0b	109	1	Some	some	DT
cord-347000-zxytdb0b	109	2	plants	plant	NNS
cord-347000-zxytdb0b	109	3	naturally	naturally	RB
cord-347000-zxytdb0b	109	4	form	form	VBP
cord-347000-zxytdb0b	109	5	antagonists	antagonist	NNS
cord-347000-zxytdb0b	109	6	to	to	IN
cord-347000-zxytdb0b	109	7	QS	QS	NNP
cord-347000-zxytdb0b	109	8	molecules	molecule	NNS
cord-347000-zxytdb0b	109	9	(	(	-LRB-
cord-347000-zxytdb0b	109	10	acylated	acylated	NNP
cord-347000-zxytdb0b	109	11	homoserine	homoserine	NNP
cord-347000-zxytdb0b	109	12	lactones	lactones	NNPS
cord-347000-zxytdb0b	109	13	)	)	-RRB-
cord-347000-zxytdb0b	109	14	as	as	IN
cord-347000-zxytdb0b	109	15	a	a	DT
cord-347000-zxytdb0b	109	16	defence	defence	NN
cord-347000-zxytdb0b	109	17	mechanism	mechanism	NN
cord-347000-zxytdb0b	109	18	.	.	.
cord-347000-zxytdb0b	110	1	QS	QS	NNP
cord-347000-zxytdb0b	110	2	is	be	VBZ
cord-347000-zxytdb0b	110	3	therefore	therefore	RB
cord-347000-zxytdb0b	110	4	a	a	DT
cord-347000-zxytdb0b	110	5	potential	potential	JJ
cord-347000-zxytdb0b	110	6	target	target	NN
cord-347000-zxytdb0b	110	7	for	for	IN
cord-347000-zxytdb0b	110	8	new	new	JJ
cord-347000-zxytdb0b	110	9	antimicrobial	antimicrobial	JJ
cord-347000-zxytdb0b	110	10	therapies	therapy	NNS
cord-347000-zxytdb0b	110	11	.	.	.
cord-347000-zxytdb0b	111	1	In	in	IN
cord-347000-zxytdb0b	111	2	the	the	DT
cord-347000-zxytdb0b	111	3	laboratory	laboratory	NN
cord-347000-zxytdb0b	111	4	,	,	,
cord-347000-zxytdb0b	111	5	bacteria	bacteria	NNS
cord-347000-zxytdb0b	111	6	isolated	isolate	VBN
cord-347000-zxytdb0b	111	7	from	from	IN
cord-347000-zxytdb0b	111	8	chronically	chronically	RB
cord-347000-zxytdb0b	111	9	infected	infect	VBN
cord-347000-zxytdb0b	111	10	patients	patient	NNS
cord-347000-zxytdb0b	111	11	differ	differ	VBP
cord-347000-zxytdb0b	111	12	from	from	IN
cord-347000-zxytdb0b	111	13	the	the	DT
cord-347000-zxytdb0b	111	14	usual	usual	JJ
cord-347000-zxytdb0b	111	15	P.	P.	NNP
cord-347000-zxytdb0b	111	16	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	111	17	cultured	culture	VBN
cord-347000-zxytdb0b	111	18	from	from	IN
cord-347000-zxytdb0b	111	19	acute	acute	JJ
cord-347000-zxytdb0b	111	20	infection	infection	NN
cord-347000-zxytdb0b	111	21	.	.	.
cord-347000-zxytdb0b	112	1	Clonal	Clonal	NNP
cord-347000-zxytdb0b	112	2	bacteria	bacteria	NNS
cord-347000-zxytdb0b	112	3	can	can	MD
cord-347000-zxytdb0b	112	4	form	form	VB
cord-347000-zxytdb0b	112	5	colonies	colony	NNS
cord-347000-zxytdb0b	112	6	with	with	IN
cord-347000-zxytdb0b	112	7	different	different	JJ
cord-347000-zxytdb0b	112	8	appearance	appearance	NN
cord-347000-zxytdb0b	112	9	referred	refer	VBD
cord-347000-zxytdb0b	112	10	to	to	IN
cord-347000-zxytdb0b	112	11	as	as	IN
cord-347000-zxytdb0b	112	12	colonial	colonial	JJ
cord-347000-zxytdb0b	112	13	morphotypes	morphotype	NNS
cord-347000-zxytdb0b	112	14	.	.	.
cord-347000-zxytdb0b	113	1	The	the	DT
cord-347000-zxytdb0b	113	2	classical	classical	JJ
cord-347000-zxytdb0b	113	3	CF	cf	NN
cord-347000-zxytdb0b	113	4	isolate	isolate	NN
cord-347000-zxytdb0b	113	5	is	be	VBZ
cord-347000-zxytdb0b	113	6	mucoid	mucoid	JJ
cord-347000-zxytdb0b	113	7	,	,	,
cord-347000-zxytdb0b	113	8	due	due	IN
cord-347000-zxytdb0b	113	9	to	to	IN
cord-347000-zxytdb0b	113	10	hyperproduction	hyperproduction	NN
cord-347000-zxytdb0b	113	11	of	of	IN
cord-347000-zxytdb0b	113	12	alginate	alginate	NN
cord-347000-zxytdb0b	113	13	.	.	.
cord-347000-zxytdb0b	114	1	Other	other	JJ
cord-347000-zxytdb0b	114	2	morphotypes	morphotype	NNS
cord-347000-zxytdb0b	114	3	include	include	VBP
cord-347000-zxytdb0b	114	4	bacteria	bacteria	NNS
cord-347000-zxytdb0b	114	5	that	that	WDT
cord-347000-zxytdb0b	114	6	look	look	VBP
cord-347000-zxytdb0b	114	7	like	like	IN
cord-347000-zxytdb0b	114	8	coliforms	coliform	NNS
cord-347000-zxytdb0b	114	9	,	,	,
cord-347000-zxytdb0b	114	10	non	non	JJ
cord-347000-zxytdb0b	114	11	-	-	JJ
cord-347000-zxytdb0b	114	12	pigmented	pigmented	JJ
cord-347000-zxytdb0b	114	13	forms	form	NNS
cord-347000-zxytdb0b	114	14	and	and	CC
cord-347000-zxytdb0b	114	15	slow	slow	RB
cord-347000-zxytdb0b	114	16	-	-	HYPH
cord-347000-zxytdb0b	114	17	growing	grow	VBG
cord-347000-zxytdb0b	114	18	SCVs	scv	NNS
cord-347000-zxytdb0b	114	19	.	.	.
cord-347000-zxytdb0b	115	1	24	24	CD
cord-347000-zxytdb0b	116	1	These	these	DT
cord-347000-zxytdb0b	116	2	latter	latter	RB
cord-347000-zxytdb0b	116	3	are	be	VBP
cord-347000-zxytdb0b	116	4	hydrophobic	hydrophobic	JJ
cord-347000-zxytdb0b	116	5	,	,	,
cord-347000-zxytdb0b	116	6	have	have	VBP
cord-347000-zxytdb0b	116	7	reduced	reduce	VBN
cord-347000-zxytdb0b	116	8	swimming	swimming	NN
cord-347000-zxytdb0b	116	9	motility	motility	NN
cord-347000-zxytdb0b	116	10	and	and	CC
cord-347000-zxytdb0b	116	11	form	form	VB
cord-347000-zxytdb0b	116	12	good	good	JJ
cord-347000-zxytdb0b	116	13	biofilms	biofilm	NNS
cord-347000-zxytdb0b	116	14	in	in	IN
cord-347000-zxytdb0b	116	15	vitro	vitro	FW
cord-347000-zxytdb0b	116	16	.	.	.
cord-347000-zxytdb0b	117	1	They	-PRON-	PRP
cord-347000-zxytdb0b	117	2	may	may	MD
cord-347000-zxytdb0b	117	3	be	be	VB
cord-347000-zxytdb0b	117	4	missed	miss	VBN
cord-347000-zxytdb0b	117	5	in	in	IN
cord-347000-zxytdb0b	117	6	the	the	DT
cord-347000-zxytdb0b	117	7	routine	routine	JJ
cord-347000-zxytdb0b	117	8	laboratory	laboratory	NN
cord-347000-zxytdb0b	117	9	because	because	IN
cord-347000-zxytdb0b	117	10	they	-PRON-	PRP
cord-347000-zxytdb0b	117	11	can	can	MD
cord-347000-zxytdb0b	117	12	take	take	VB
cord-347000-zxytdb0b	117	13	more	more	JJR
cord-347000-zxytdb0b	117	14	than	than	IN
cord-347000-zxytdb0b	117	15	48	48	CD
cord-347000-zxytdb0b	117	16	h	h	NN
cord-347000-zxytdb0b	117	17	to	to	TO
cord-347000-zxytdb0b	117	18	appear	appear	VB
cord-347000-zxytdb0b	117	19	.	.	.
cord-347000-zxytdb0b	118	1	Phenotypic	phenotypic	JJ
cord-347000-zxytdb0b	118	2	variation	variation	NN
cord-347000-zxytdb0b	118	3	is	be	VBZ
cord-347000-zxytdb0b	118	4	not	not	RB
cord-347000-zxytdb0b	118	5	restricted	restrict	VBN
cord-347000-zxytdb0b	118	6	to	to	IN
cord-347000-zxytdb0b	118	7	colonial	colonial	JJ
cord-347000-zxytdb0b	118	8	morphology	morphology	NN
cord-347000-zxytdb0b	118	9	but	but	CC
cord-347000-zxytdb0b	118	10	includes	include	VBZ
cord-347000-zxytdb0b	118	11	type	type	NN
cord-347000-zxytdb0b	118	12	III	iii	CD
cord-347000-zxytdb0b	118	13	secretion	secretion	NN
cord-347000-zxytdb0b	118	14	,	,	,
cord-347000-zxytdb0b	118	15	auxotrophy	auxotrophy	NN
cord-347000-zxytdb0b	118	16	,	,	,
cord-347000-zxytdb0b	118	17	lipopolysaccharide	lipopolysaccharide	NN
cord-347000-zxytdb0b	118	18	(	(	-LRB-
cord-347000-zxytdb0b	118	19	LPS	LPS	NNP
cord-347000-zxytdb0b	118	20	)	)	-RRB-
cord-347000-zxytdb0b	118	21	modification	modification	NN
cord-347000-zxytdb0b	118	22	(	(	-LRB-
cord-347000-zxytdb0b	118	23	smooth	smooth	JJ
cord-347000-zxytdb0b	118	24	to	to	IN
cord-347000-zxytdb0b	118	25	rough	rough	JJ
cord-347000-zxytdb0b	118	26	)	)	-RRB-
cord-347000-zxytdb0b	118	27	and	and	CC
cord-347000-zxytdb0b	118	28	both	both	CC
cord-347000-zxytdb0b	118	29	resistance	resistance	NN
cord-347000-zxytdb0b	118	30	and	and	CC
cord-347000-zxytdb0b	118	31	hypersusceptibility	hypersusceptibility	NN
cord-347000-zxytdb0b	118	32	to	to	IN
cord-347000-zxytdb0b	118	33	antibiotics	antibiotic	NNS
cord-347000-zxytdb0b	118	34	.	.	.
cord-347000-zxytdb0b	119	1	Variability	variability	NN
cord-347000-zxytdb0b	119	2	in	in	IN
cord-347000-zxytdb0b	119	3	antibiotic	antibiotic	JJ
cord-347000-zxytdb0b	119	4	susceptibility	susceptibility	NN
cord-347000-zxytdb0b	119	5	in	in	IN
cord-347000-zxytdb0b	119	6	a	a	DT
cord-347000-zxytdb0b	119	7	population	population	NN
cord-347000-zxytdb0b	119	8	of	of	IN
cord-347000-zxytdb0b	119	9	bacteria	bacteria	NNS
cord-347000-zxytdb0b	119	10	from	from	IN
cord-347000-zxytdb0b	119	11	a	a	DT
cord-347000-zxytdb0b	119	12	CF	cf	NN
cord-347000-zxytdb0b	119	13	sputum	sputum	NN
cord-347000-zxytdb0b	119	14	includes	include	VBZ
cord-347000-zxytdb0b	119	15	differences	difference	NNS
cord-347000-zxytdb0b	119	16	between	between	IN
cord-347000-zxytdb0b	119	17	bacteria	bacteria	NNS
cord-347000-zxytdb0b	119	18	of	of	IN
cord-347000-zxytdb0b	119	19	the	the	DT
cord-347000-zxytdb0b	119	20	same	same	JJ
cord-347000-zxytdb0b	119	21	clone	clone	NN
cord-347000-zxytdb0b	119	22	and	and	CC
cord-347000-zxytdb0b	119	23	morphotype	morphotype	NN
cord-347000-zxytdb0b	119	24	.	.	.
cord-347000-zxytdb0b	120	1	As	as	IN
cord-347000-zxytdb0b	120	2	a	a	DT
cord-347000-zxytdb0b	120	3	result	result	NN
cord-347000-zxytdb0b	120	4	,	,	,
cord-347000-zxytdb0b	120	5	susceptibility	susceptibility	NN
cord-347000-zxytdb0b	120	6	testing	testing	NN
cord-347000-zxytdb0b	120	7	is	be	VBZ
cord-347000-zxytdb0b	120	8	poorly	poorly	RB
cord-347000-zxytdb0b	120	9	reproducible	reproducible	JJ
cord-347000-zxytdb0b	120	10	as	as	IN
cord-347000-zxytdb0b	120	11	the	the	DT
cord-347000-zxytdb0b	120	12	result	result	NN
cord-347000-zxytdb0b	120	13	may	may	MD
cord-347000-zxytdb0b	120	14	depend	depend	VB
cord-347000-zxytdb0b	120	15	on	on	IN
cord-347000-zxytdb0b	120	16	which	which	WDT
cord-347000-zxytdb0b	120	17	bacteria	bacteria	NNS
cord-347000-zxytdb0b	120	18	are	be	VBP
cord-347000-zxytdb0b	120	19	picked	pick	VBN
cord-347000-zxytdb0b	120	20	for	for	IN
cord-347000-zxytdb0b	120	21	testing	testing	NN
cord-347000-zxytdb0b	120	22	.	.	.
cord-347000-zxytdb0b	121	1	25	25	CD
cord-347000-zxytdb0b	122	1	The	the	DT
cord-347000-zxytdb0b	122	2	role	role	NN
cord-347000-zxytdb0b	122	3	of	of	IN
cord-347000-zxytdb0b	122	4	antimicrobial	antimicrobial	JJ
cord-347000-zxytdb0b	122	5	susceptibility	susceptibility	NN
cord-347000-zxytdb0b	122	6	testing	testing	NN
cord-347000-zxytdb0b	122	7	for	for	IN
cord-347000-zxytdb0b	122	8	helping	help	VBG
cord-347000-zxytdb0b	122	9	the	the	DT
cord-347000-zxytdb0b	122	10	clinician	clinician	NN
cord-347000-zxytdb0b	122	11	who	who	WP
cord-347000-zxytdb0b	122	12	chose	choose	VBD
cord-347000-zxytdb0b	122	13	the	the	DT
cord-347000-zxytdb0b	122	14	antibiotics	antibiotic	NNS
cord-347000-zxytdb0b	122	15	to	to	TO
cord-347000-zxytdb0b	122	16	treat	treat	VB
cord-347000-zxytdb0b	122	17	acute	acute	JJ
cord-347000-zxytdb0b	122	18	exacerbations	exacerbation	NNS
cord-347000-zxytdb0b	122	19	in	in	IN
cord-347000-zxytdb0b	122	20	CF	CF	NNP
cord-347000-zxytdb0b	122	21	is	be	VBZ
cord-347000-zxytdb0b	122	22	controversial	controversial	JJ
cord-347000-zxytdb0b	122	23	.	.	.
cord-347000-zxytdb0b	123	1	There	there	EX
cord-347000-zxytdb0b	123	2	are	be	VBP
cord-347000-zxytdb0b	123	3	anecdotal	anecdotal	JJ
cord-347000-zxytdb0b	123	4	reports	report	NNS
cord-347000-zxytdb0b	123	5	of	of	IN
cord-347000-zxytdb0b	123	6	poor	poor	JJ
cord-347000-zxytdb0b	123	7	correlation	correlation	NN
cord-347000-zxytdb0b	123	8	between	between	IN
cord-347000-zxytdb0b	123	9	antimicrobial	antimicrobial	JJ
cord-347000-zxytdb0b	123	10	susceptibility	susceptibility	NN
cord-347000-zxytdb0b	123	11	and	and	CC
cord-347000-zxytdb0b	123	12	treatment	treatment	NN
cord-347000-zxytdb0b	123	13	of	of	IN
cord-347000-zxytdb0b	123	14	acute	acute	JJ
cord-347000-zxytdb0b	123	15	exacerbation	exacerbation	NN
cord-347000-zxytdb0b	123	16	.	.	.
cord-347000-zxytdb0b	124	1	Methods	method	NNS
cord-347000-zxytdb0b	124	2	to	to	TO
cord-347000-zxytdb0b	124	3	improve	improve	VB
cord-347000-zxytdb0b	124	4	the	the	DT
cord-347000-zxytdb0b	124	5	detection	detection	NN
cord-347000-zxytdb0b	124	6	of	of	IN
cord-347000-zxytdb0b	124	7	resistant	resistant	JJ
cord-347000-zxytdb0b	124	8	sub	sub	NN
cord-347000-zxytdb0b	124	9	-	-	NNS
cord-347000-zxytdb0b	124	10	populations	population	NNS
cord-347000-zxytdb0b	124	11	have	have	VBP
cord-347000-zxytdb0b	124	12	been	be	VBN
cord-347000-zxytdb0b	124	13	described	describe	VBN
cord-347000-zxytdb0b	124	14	.	.	.
cord-347000-zxytdb0b	125	1	25	25	CD
cord-347000-zxytdb0b	125	2	,	,	,
cord-347000-zxytdb0b	125	3	26	26	CD
cord-347000-zxytdb0b	126	1	However	however	RB
cord-347000-zxytdb0b	126	2	,	,	,
cord-347000-zxytdb0b	126	3	the	the	DT
cord-347000-zxytdb0b	126	4	only	only	JJ
cord-347000-zxytdb0b	126	5	big	big	JJ
cord-347000-zxytdb0b	126	6	study	study	NN
cord-347000-zxytdb0b	126	7	to	to	TO
cord-347000-zxytdb0b	126	8	correlate	correlate	VB
cord-347000-zxytdb0b	126	9	antibiotic	antibiotic	JJ
cord-347000-zxytdb0b	126	10	resistance	resistance	NN
cord-347000-zxytdb0b	126	11	to	to	IN
cord-347000-zxytdb0b	126	12	clinical	clinical	JJ
cord-347000-zxytdb0b	126	13	response	response	NN
cord-347000-zxytdb0b	126	14	showed	show	VBD
cord-347000-zxytdb0b	126	15	that	that	IN
cord-347000-zxytdb0b	126	16	lung	lung	NN
cord-347000-zxytdb0b	126	17	function	function	NN
cord-347000-zxytdb0b	126	18	(	(	-LRB-
cord-347000-zxytdb0b	126	19	forced	force	VBN
cord-347000-zxytdb0b	126	20	expiratory	expiratory	JJ
cord-347000-zxytdb0b	126	21	volume	volume	NN
cord-347000-zxytdb0b	126	22	in	in	IN
cord-347000-zxytdb0b	126	23	one	one	CD
cord-347000-zxytdb0b	126	24	second	second	NN
cord-347000-zxytdb0b	126	25	)	)	-RRB-
cord-347000-zxytdb0b	126	26	improved	improve	VBD
cord-347000-zxytdb0b	126	27	in	in	IN
cord-347000-zxytdb0b	126	28	patients	patient	NNS
cord-347000-zxytdb0b	126	29	in	in	IN
cord-347000-zxytdb0b	126	30	spite	spite	NN
cord-347000-zxytdb0b	126	31	of	of	IN
cord-347000-zxytdb0b	126	32	treatment	treatment	NN
cord-347000-zxytdb0b	126	33	with	with	IN
cord-347000-zxytdb0b	126	34	antibiotics	antibiotic	NNS
cord-347000-zxytdb0b	126	35	to	to	TO
cord-347000-zxytdb0b	126	36	which	which	WDT
cord-347000-zxytdb0b	126	37	their	-PRON-	PRP$
cord-347000-zxytdb0b	126	38	P.	P.	NNP
cord-347000-zxytdb0b	126	39	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	126	40	were	be	VBD
cord-347000-zxytdb0b	126	41	resistant	resistant	JJ
cord-347000-zxytdb0b	126	42	in	in	IN
cord-347000-zxytdb0b	126	43	vitro	vitro	FW
cord-347000-zxytdb0b	126	44	.	.	.
cord-347000-zxytdb0b	127	1	27	27	CD
cord-347000-zxytdb0b	127	2	Antibiotics	antibiotic	NNS
cord-347000-zxytdb0b	127	3	seldom	seldom	RB
cord-347000-zxytdb0b	127	4	if	if	IN
cord-347000-zxytdb0b	127	5	ever	ever	RB
cord-347000-zxytdb0b	127	6	eradicate	eradicate	VBP
cord-347000-zxytdb0b	127	7	chronic	chronic	JJ
cord-347000-zxytdb0b	127	8	infection	infection	NN
cord-347000-zxytdb0b	127	9	with	with	IN
cord-347000-zxytdb0b	127	10	P.	P.	NNP
cord-347000-zxytdb0b	127	11	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	127	12	from	from	IN
cord-347000-zxytdb0b	127	13	the	the	DT
cord-347000-zxytdb0b	127	14	CF	CF	NNP
cord-347000-zxytdb0b	127	15	lung	lung	NN
cord-347000-zxytdb0b	127	16	.	.	.
cord-347000-zxytdb0b	128	1	Even	even	RB
cord-347000-zxytdb0b	128	2	the	the	DT
cord-347000-zxytdb0b	128	3	resolution	resolution	NN
cord-347000-zxytdb0b	128	4	of	of	IN
cord-347000-zxytdb0b	128	5	symptoms	symptom	NNS
cord-347000-zxytdb0b	128	6	and	and	CC
cord-347000-zxytdb0b	128	7	signs	sign	NNS
cord-347000-zxytdb0b	128	8	of	of	IN
cord-347000-zxytdb0b	128	9	an	an	DT
cord-347000-zxytdb0b	128	10	exacerbation	exacerbation	NN
cord-347000-zxytdb0b	128	11	may	may	MD
cord-347000-zxytdb0b	128	12	not	not	RB
cord-347000-zxytdb0b	128	13	be	be	VB
cord-347000-zxytdb0b	128	14	matched	match	VBN
cord-347000-zxytdb0b	128	15	with	with	IN
cord-347000-zxytdb0b	128	16	a	a	DT
cord-347000-zxytdb0b	128	17	significant	significant	JJ
cord-347000-zxytdb0b	128	18	reduction	reduction	NN
cord-347000-zxytdb0b	128	19	in	in	IN
cord-347000-zxytdb0b	128	20	bacterial	bacterial	JJ
cord-347000-zxytdb0b	128	21	load	load	NN
cord-347000-zxytdb0b	128	22	.	.	.
cord-347000-zxytdb0b	129	1	It	-PRON-	PRP
cord-347000-zxytdb0b	129	2	may	may	MD
cord-347000-zxytdb0b	129	3	be	be	VB
cord-347000-zxytdb0b	129	4	therefore	therefore	RB
cord-347000-zxytdb0b	129	5	that	that	IN
cord-347000-zxytdb0b	129	6	antibiotics	antibiotic	NNS
cord-347000-zxytdb0b	129	7	are	be	VBP
cord-347000-zxytdb0b	129	8	effective	effective	JJ
cord-347000-zxytdb0b	129	9	without	without	IN
cord-347000-zxytdb0b	129	10	actually	actually	RB
cord-347000-zxytdb0b	129	11	inhibiting	inhibit	VBG
cord-347000-zxytdb0b	129	12	or	or	CC
cord-347000-zxytdb0b	129	13	killing	kill	VBG
cord-347000-zxytdb0b	129	14	the	the	DT
cord-347000-zxytdb0b	129	15	bacteria	bacteria	NNS
cord-347000-zxytdb0b	129	16	-	-	:
cord-347000-zxytdb0b	129	17	the	the	DT
cord-347000-zxytdb0b	129	18	so	so	RB
cord-347000-zxytdb0b	129	19	-	-	HYPH
cord-347000-zxytdb0b	129	20	called	call	VBN
cord-347000-zxytdb0b	129	21	sub	sub	JJ
cord-347000-zxytdb0b	129	22	-	-	JJ
cord-347000-zxytdb0b	129	23	minimum	minimum	JJ
cord-347000-zxytdb0b	129	24	inhibitory	inhibitory	JJ
cord-347000-zxytdb0b	129	25	concentration	concentration	NN
cord-347000-zxytdb0b	129	26	(	(	-LRB-
cord-347000-zxytdb0b	129	27	MIC	MIC	NNP
cord-347000-zxytdb0b	129	28	)	)	-RRB-
cord-347000-zxytdb0b	129	29	effect	effect	NN
cord-347000-zxytdb0b	129	30	.	.	.
cord-347000-zxytdb0b	130	1	This	this	DT
cord-347000-zxytdb0b	130	2	may	may	MD
cord-347000-zxytdb0b	130	3	also	also	RB
cord-347000-zxytdb0b	130	4	explain	explain	VB
cord-347000-zxytdb0b	130	5	the	the	DT
cord-347000-zxytdb0b	130	6	successful	successful	JJ
cord-347000-zxytdb0b	130	7	treatment	treatment	NN
cord-347000-zxytdb0b	130	8	of	of	IN
cord-347000-zxytdb0b	130	9	infection	infection	NN
cord-347000-zxytdb0b	130	10	with	with	IN
cord-347000-zxytdb0b	130	11	antibiotics	antibiotic	NNS
cord-347000-zxytdb0b	130	12	,	,	,
cord-347000-zxytdb0b	130	13	even	even	RB
cord-347000-zxytdb0b	130	14	though	though	IN
cord-347000-zxytdb0b	130	15	the	the	DT
cord-347000-zxytdb0b	130	16	bacteria	bacteria	NNS
cord-347000-zxytdb0b	130	17	are	be	VBP
cord-347000-zxytdb0b	130	18	resistant	resistant	JJ
cord-347000-zxytdb0b	130	19	.	.	.
cord-347000-zxytdb0b	131	1	For	for	IN
cord-347000-zxytdb0b	131	2	example	example	NN
cord-347000-zxytdb0b	131	3	,	,	,
cord-347000-zxytdb0b	131	4	at	at	IN
cord-347000-zxytdb0b	131	5	sub	sub	JJ
cord-347000-zxytdb0b	131	6	-	-	JJ
cord-347000-zxytdb0b	131	7	MIC	mic	NN
cord-347000-zxytdb0b	131	8	concentration	concentration	NN
cord-347000-zxytdb0b	131	9	,	,	,
cord-347000-zxytdb0b	131	10	ceftazidime	ceftazidime	NNP
cord-347000-zxytdb0b	131	11	can	can	MD
cord-347000-zxytdb0b	131	12	inhibit	inhibit	VB
cord-347000-zxytdb0b	131	13	attachment	attachment	NN
cord-347000-zxytdb0b	131	14	to	to	IN
cord-347000-zxytdb0b	131	15	cells	cell	NNS
cord-347000-zxytdb0b	131	16	and	and	CC
cord-347000-zxytdb0b	131	17	ciprofloxacin	ciprofloxacin	NN
cord-347000-zxytdb0b	131	18	can	can	MD
cord-347000-zxytdb0b	131	19	reduce	reduce	VB
cord-347000-zxytdb0b	131	20	alginate	alginate	NN
cord-347000-zxytdb0b	131	21	production	production	NN
cord-347000-zxytdb0b	131	22	.	.	.
cord-347000-zxytdb0b	132	1	28	28	CD
cord-347000-zxytdb0b	133	1	Although	although	IN
cord-347000-zxytdb0b	133	2	P.	P.	NNP
cord-347000-zxytdb0b	133	3	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	133	4	is	be	VBZ
cord-347000-zxytdb0b	133	5	intrinsically	intrinsically	RB
cord-347000-zxytdb0b	133	6	resistant	resistant	JJ
cord-347000-zxytdb0b	133	7	,	,	,
cord-347000-zxytdb0b	133	8	azithromycin	azithromycin	NN
cord-347000-zxytdb0b	133	9	may	may	MD
cord-347000-zxytdb0b	133	10	reduce	reduce	VB
cord-347000-zxytdb0b	133	11	pathogenicity	pathogenicity	NN
cord-347000-zxytdb0b	133	12	by	by	IN
cord-347000-zxytdb0b	133	13	inhibition	inhibition	NN
cord-347000-zxytdb0b	133	14	of	of	IN
cord-347000-zxytdb0b	133	15	QS	QS	NNP
cord-347000-zxytdb0b	133	16	and	and	CC
cord-347000-zxytdb0b	133	17	biofilm	biofilm	NN
cord-347000-zxytdb0b	133	18	formation	formation	NN
cord-347000-zxytdb0b	133	19	.	.	.
cord-347000-zxytdb0b	134	1	Pseudomonas	Pseudomonas	NNP
cord-347000-zxytdb0b	134	2	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	134	3	is	be	VBZ
cord-347000-zxytdb0b	134	4	innately	innately	RB
cord-347000-zxytdb0b	134	5	resistant	resistant	JJ
cord-347000-zxytdb0b	134	6	to	to	IN
cord-347000-zxytdb0b	134	7	many	many	JJ
cord-347000-zxytdb0b	134	8	antibiotics	antibiotic	NNS
cord-347000-zxytdb0b	134	9	and	and	CC
cord-347000-zxytdb0b	134	10	acquired	acquire	VBN
cord-347000-zxytdb0b	134	11	resistance	resistance	NN
cord-347000-zxytdb0b	134	12	is	be	VBZ
cord-347000-zxytdb0b	134	13	increasing	increase	VBG
cord-347000-zxytdb0b	134	14	.	.	.
cord-347000-zxytdb0b	135	1	29	29	CD
cord-347000-zxytdb0b	135	2	Synergy	Synergy	NNP
cord-347000-zxytdb0b	135	3	testing	testing	NN
cord-347000-zxytdb0b	135	4	has	have	VBZ
cord-347000-zxytdb0b	135	5	been	be	VBN
cord-347000-zxytdb0b	135	6	advocated	advocate	VBN
cord-347000-zxytdb0b	135	7	as	as	IN
cord-347000-zxytdb0b	135	8	a	a	DT
cord-347000-zxytdb0b	135	9	way	way	NN
cord-347000-zxytdb0b	135	10	to	to	TO
cord-347000-zxytdb0b	135	11	find	find	VB
cord-347000-zxytdb0b	135	12	combinations	combination	NNS
cord-347000-zxytdb0b	135	13	of	of	IN
cord-347000-zxytdb0b	135	14	antibiotics	antibiotic	NNS
cord-347000-zxytdb0b	135	15	effective	effective	JJ
cord-347000-zxytdb0b	135	16	against	against	IN
cord-347000-zxytdb0b	135	17	multiresistant	multiresistant	NN
cord-347000-zxytdb0b	135	18	P.	P.	NNP
cord-347000-zxytdb0b	135	19	aeruginosa	aeruginosa	NNP
cord-347000-zxytdb0b	135	20	.	.	.
cord-347000-zxytdb0b	136	1	Time	time	NN
cord-347000-zxytdb0b	136	2	-	-	HYPH
cord-347000-zxytdb0b	136	3	kill	kill	NN
cord-347000-zxytdb0b	136	4	curves	curve	NNS
cord-347000-zxytdb0b	136	5	,	,	,
cord-347000-zxytdb0b	136	6	chequerboard	chequerboard	NN
cord-347000-zxytdb0b	136	7	methods	method	NNS
cord-347000-zxytdb0b	136	8	and	and	CC
cord-347000-zxytdb0b	136	9	the	the	DT
cord-347000-zxytdb0b	136	10	multiple	multiple	JJ
cord-347000-zxytdb0b	136	11	combination	combination	NN
cord-347000-zxytdb0b	136	12	bactericidal	bactericidal	JJ
cord-347000-zxytdb0b	136	13	test	test	NN
cord-347000-zxytdb0b	136	14	(	(	-LRB-
cord-347000-zxytdb0b	136	15	MCBT	MCBT	NNP
cord-347000-zxytdb0b	136	16	)	)	-RRB-
cord-347000-zxytdb0b	136	17	are	be	VBP
cord-347000-zxytdb0b	136	18	the	the	DT
cord-347000-zxytdb0b	136	19	most	most	RBS
cord-347000-zxytdb0b	136	20	commonly	commonly	RB
cord-347000-zxytdb0b	136	21	used	use	VBN
cord-347000-zxytdb0b	136	22	methods	method	NNS
cord-347000-zxytdb0b	136	23	and	and	CC
cord-347000-zxytdb0b	136	24	synergy	synergy	NN
cord-347000-zxytdb0b	136	25	can	can	MD
cord-347000-zxytdb0b	136	26	be	be	VB
cord-347000-zxytdb0b	136	27	shown	show	VBN
cord-347000-zxytdb0b	136	28	in	in	IN
cord-347000-zxytdb0b	136	29	vitro	vitro	FW
cord-347000-zxytdb0b	136	30	.	.	.
cord-347000-zxytdb0b	137	1	Different	different	JJ
cord-347000-zxytdb0b	137	2	results	result	NNS
cord-347000-zxytdb0b	137	3	can	can	MD
cord-347000-zxytdb0b	137	4	however	however	RB
cord-347000-zxytdb0b	137	5	be	be	VB
cord-347000-zxytdb0b	137	6	obtained	obtain	VBN
cord-347000-zxytdb0b	137	7	with	with	IN
cord-347000-zxytdb0b	137	8	different	different	JJ
cord-347000-zxytdb0b	137	9	methods	method	NNS
cord-347000-zxytdb0b	137	10	and	and	CC
cord-347000-zxytdb0b	137	11	there	there	EX
cord-347000-zxytdb0b	137	12	is	be	VBZ
cord-347000-zxytdb0b	137	13	no	no	DT
cord-347000-zxytdb0b	137	14	accepted	accept	VBN
cord-347000-zxytdb0b	137	15	reference	reference	NN
cord-347000-zxytdb0b	137	16	standard	standard	NN
cord-347000-zxytdb0b	137	17	.	.	.
cord-347000-zxytdb0b	138	1	30	30	LS
cord-347000-zxytdb0b	138	2	There	there	EX
cord-347000-zxytdb0b	138	3	are	be	VBP
cord-347000-zxytdb0b	138	4	few	few	JJ
cord-347000-zxytdb0b	138	5	studies	study	NNS
cord-347000-zxytdb0b	138	6	that	that	WDT
cord-347000-zxytdb0b	138	7	attempt	attempt	VBP
cord-347000-zxytdb0b	138	8	to	to	TO
cord-347000-zxytdb0b	138	9	correlate	correlate	VB
cord-347000-zxytdb0b	138	10	the	the	DT
cord-347000-zxytdb0b	138	11	results	result	NNS
cord-347000-zxytdb0b	138	12	of	of	IN
cord-347000-zxytdb0b	138	13	synergy	synergy	NN
cord-347000-zxytdb0b	138	14	testing	testing	NN
cord-347000-zxytdb0b	138	15	with	with	IN
cord-347000-zxytdb0b	138	16	the	the	DT
cord-347000-zxytdb0b	138	17	clinical	clinical	JJ
cord-347000-zxytdb0b	138	18	outcome	outcome	NN
cord-347000-zxytdb0b	138	19	.	.	.
cord-347000-zxytdb0b	139	1	One	one	CD
cord-347000-zxytdb0b	139	2	randomized	randomized	JJ
cord-347000-zxytdb0b	139	3	prospective	prospective	JJ
cord-347000-zxytdb0b	139	4	study	study	NN
cord-347000-zxytdb0b	139	5	compared	compare	VBD
cord-347000-zxytdb0b	139	6	the	the	DT
cord-347000-zxytdb0b	139	7	MCBT	MCBT	NNS
cord-347000-zxytdb0b	139	8	with	with	IN
cord-347000-zxytdb0b	139	9	traditional	traditional	JJ
cord-347000-zxytdb0b	139	10	single	single	JJ
cord-347000-zxytdb0b	139	11	antibiotic	antibiotic	JJ
cord-347000-zxytdb0b	139	12	susceptibility	susceptibility	NN
cord-347000-zxytdb0b	139	13	testing	testing	NN
cord-347000-zxytdb0b	139	14	for	for	IN
cord-347000-zxytdb0b	139	15	determining	determine	VBG
cord-347000-zxytdb0b	139	16	treatment	treatment	NN
cord-347000-zxytdb0b	139	17	of	of	IN
cord-347000-zxytdb0b	139	18	acute	acute	JJ
cord-347000-zxytdb0b	139	19	exacerbation	exacerbation	NN
cord-347000-zxytdb0b	139	20	with	with	IN
cord-347000-zxytdb0b	139	21	a	a	DT
cord-347000-zxytdb0b	139	22	range	range	NN
cord-347000-zxytdb0b	139	23	of	of	IN
cord-347000-zxytdb0b	139	24	multi	multi	JJ
cord-347000-zxytdb0b	139	25	-	-	JJ
cord-347000-zxytdb0b	139	26	resistant	resistant	JJ
cord-347000-zxytdb0b	139	27	species	specie	NNS
cord-347000-zxytdb0b	139	28	in	in	IN
cord-347000-zxytdb0b	139	29	CF	cf	NN
cord-347000-zxytdb0b	139	30	including	include	VBG
cord-347000-zxytdb0b	139	31	P.	P.	NNP
cord-347000-zxytdb0b	139	32	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	139	33	,	,	,
cord-347000-zxytdb0b	139	34	Stenotrophomonas	Stenotrophomonas	NNP
cord-347000-zxytdb0b	139	35	maltophilia	maltophilia	NNP
cord-347000-zxytdb0b	139	36	,	,	,
cord-347000-zxytdb0b	139	37	Achromobacter	Achromobacter	NNP
cord-347000-zxytdb0b	139	38	xylosoxidans	xylosoxidans	NNP
cord-347000-zxytdb0b	139	39	and	and	CC
cord-347000-zxytdb0b	139	40	Burkholderia	Burkholderia	NNP
cord-347000-zxytdb0b	139	41	cepacia	cepacia	NNP
cord-347000-zxytdb0b	139	42	complex	complex	NN
cord-347000-zxytdb0b	139	43	(	(	-LRB-
cord-347000-zxytdb0b	139	44	Bcc	Bcc	NNP
cord-347000-zxytdb0b	139	45	)	)	-RRB-
cord-347000-zxytdb0b	139	46	.	.	.
cord-347000-zxytdb0b	140	1	This	this	DT
cord-347000-zxytdb0b	140	2	showed	show	VBD
cord-347000-zxytdb0b	140	3	no	no	DT
cord-347000-zxytdb0b	140	4	better	well	JJR
cord-347000-zxytdb0b	140	5	outcome	outcome	NN
cord-347000-zxytdb0b	140	6	when	when	WRB
cord-347000-zxytdb0b	140	7	antibiotics	antibiotic	NNS
cord-347000-zxytdb0b	140	8	were	be	VBD
cord-347000-zxytdb0b	140	9	chosen	choose	VBN
cord-347000-zxytdb0b	140	10	on	on	IN
cord-347000-zxytdb0b	140	11	the	the	DT
cord-347000-zxytdb0b	140	12	basis	basis	NN
cord-347000-zxytdb0b	140	13	of	of	IN
cord-347000-zxytdb0b	140	14	the	the	DT
cord-347000-zxytdb0b	140	15	result	result	NN
cord-347000-zxytdb0b	140	16	of	of	IN
cord-347000-zxytdb0b	140	17	MCBT	MCBT	NNP
cord-347000-zxytdb0b	140	18	.	.	.
cord-347000-zxytdb0b	141	1	31	31	CD
cord-347000-zxytdb0b	142	1	The	the	DT
cord-347000-zxytdb0b	142	2	role	role	NN
cord-347000-zxytdb0b	142	3	of	of	IN
cord-347000-zxytdb0b	142	4	current	current	JJ
cord-347000-zxytdb0b	142	5	methods	method	NNS
cord-347000-zxytdb0b	142	6	of	of	IN
cord-347000-zxytdb0b	142	7	synergy	synergy	NN
cord-347000-zxytdb0b	142	8	testing	testing	NN
cord-347000-zxytdb0b	142	9	is	be	VBZ
cord-347000-zxytdb0b	142	10	controversial	controversial	JJ
cord-347000-zxytdb0b	142	11	,	,	,
cord-347000-zxytdb0b	142	12	but	but	CC
cord-347000-zxytdb0b	142	13	there	there	EX
cord-347000-zxytdb0b	142	14	is	be	VBZ
cord-347000-zxytdb0b	142	15	a	a	DT
cord-347000-zxytdb0b	142	16	definite	definite	JJ
cord-347000-zxytdb0b	142	17	need	need	NN
cord-347000-zxytdb0b	142	18	for	for	IN
cord-347000-zxytdb0b	142	19	clinically	clinically	RB
cord-347000-zxytdb0b	142	20	validated	validate	VBN
cord-347000-zxytdb0b	142	21	in	in	IN
cord-347000-zxytdb0b	142	22	vitro	vitro	FW
cord-347000-zxytdb0b	142	23	tests	test	NNS
cord-347000-zxytdb0b	142	24	to	to	TO
cord-347000-zxytdb0b	142	25	guide	guide	VB
cord-347000-zxytdb0b	142	26	treatment	treatment	NN
cord-347000-zxytdb0b	142	27	of	of	IN
cord-347000-zxytdb0b	142	28	multi	multi	JJ
cord-347000-zxytdb0b	142	29	-	-	:
cord-347000-zxytdb0b	142	30	and	and	CC
cord-347000-zxytdb0b	142	31	pan	pan	JJ
cord-347000-zxytdb0b	142	32	-	-	JJ
cord-347000-zxytdb0b	142	33	resistant	resistant	JJ
cord-347000-zxytdb0b	142	34	bacteria	bacteria	NNS
cord-347000-zxytdb0b	142	35	at	at	IN
cord-347000-zxytdb0b	142	36	acute	acute	JJ
cord-347000-zxytdb0b	142	37	exacerbation	exacerbation	NN
cord-347000-zxytdb0b	142	38	and	and	CC
cord-347000-zxytdb0b	142	39	when	when	WRB
cord-347000-zxytdb0b	142	40	patients	patient	NNS
cord-347000-zxytdb0b	142	41	receive	receive	VBP
cord-347000-zxytdb0b	142	42	lung	lung	NN
cord-347000-zxytdb0b	142	43	transplants	transplant	NNS
cord-347000-zxytdb0b	142	44	.	.	.
cord-347000-zxytdb0b	143	1	The	the	DT
cord-347000-zxytdb0b	143	2	rapid	rapid	JJ
cord-347000-zxytdb0b	143	3	development	development	NN
cord-347000-zxytdb0b	143	4	of	of	IN
cord-347000-zxytdb0b	143	5	antibiotic	antibiotic	JJ
cord-347000-zxytdb0b	143	6	-	-	HYPH
cord-347000-zxytdb0b	143	7	resistant	resistant	JJ
cord-347000-zxytdb0b	143	8	P.	P.	NNP
cord-347000-zxytdb0b	143	9	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	143	10	may	may	MD
cord-347000-zxytdb0b	143	11	be	be	VB
cord-347000-zxytdb0b	143	12	partly	partly	RB
cord-347000-zxytdb0b	143	13	due	due	JJ
cord-347000-zxytdb0b	143	14	to	to	IN
cord-347000-zxytdb0b	143	15	the	the	DT
cord-347000-zxytdb0b	143	16	presence	presence	NN
cord-347000-zxytdb0b	143	17	of	of	IN
cord-347000-zxytdb0b	143	18	hypermutator	hypermutator	NN
cord-347000-zxytdb0b	143	19	strains	strain	NNS
cord-347000-zxytdb0b	143	20	.	.	.
cord-347000-zxytdb0b	144	1	These	these	DT
cord-347000-zxytdb0b	144	2	bacteria	bacteria	NNS
cord-347000-zxytdb0b	144	3	have	have	VBP
cord-347000-zxytdb0b	144	4	defects	defect	NNS
cord-347000-zxytdb0b	144	5	in	in	IN
cord-347000-zxytdb0b	144	6	their	-PRON-	PRP$
cord-347000-zxytdb0b	144	7	ability	ability	NN
cord-347000-zxytdb0b	144	8	to	to	TO
cord-347000-zxytdb0b	144	9	correct	correct	VB
cord-347000-zxytdb0b	144	10	mistakes	mistake	NNS
cord-347000-zxytdb0b	144	11	in	in	IN
cord-347000-zxytdb0b	144	12	DNA	dna	NN
cord-347000-zxytdb0b	144	13	replication	replication	NN
cord-347000-zxytdb0b	144	14	because	because	IN
cord-347000-zxytdb0b	144	15	of	of	IN
cord-347000-zxytdb0b	144	16	a	a	DT
cord-347000-zxytdb0b	144	17	range	range	NN
cord-347000-zxytdb0b	144	18	of	of	IN
cord-347000-zxytdb0b	144	19	mutations	mutation	NNS
cord-347000-zxytdb0b	144	20	,	,	,
cord-347000-zxytdb0b	144	21	including	include	VBG
cord-347000-zxytdb0b	144	22	in	in	IN
cord-347000-zxytdb0b	144	23	the	the	DT
cord-347000-zxytdb0b	144	24	mismatch	mismatch	NN
cord-347000-zxytdb0b	144	25	repair	repair	NN
cord-347000-zxytdb0b	144	26	genes	gene	NNS
cord-347000-zxytdb0b	144	27	such	such	JJ
cord-347000-zxytdb0b	144	28	as	as	IN
cord-347000-zxytdb0b	144	29	mutS.	mutS.	NNP
cord-347000-zxytdb0b	144	30	Strong	strong	JJ
cord-347000-zxytdb0b	144	31	mutators	mutator	NNS
cord-347000-zxytdb0b	144	32	may	may	MD
cord-347000-zxytdb0b	144	33	have	have	VB
cord-347000-zxytdb0b	144	34	a	a	DT
cord-347000-zxytdb0b	144	35	mutation	mutation	NN
cord-347000-zxytdb0b	144	36	rate	rate	NN
cord-347000-zxytdb0b	144	37	as	as	RB
cord-347000-zxytdb0b	144	38	high	high	JJ
cord-347000-zxytdb0b	144	39	as	as	IN
cord-347000-zxytdb0b	144	40	1Â	1â	CD
cord-347000-zxytdb0b	144	41	10	10	CD
cord-347000-zxytdb0b	144	42	25	25	CD
cord-347000-zxytdb0b	144	43	to	to	TO
cord-347000-zxytdb0b	144	44	10	10	CD
cord-347000-zxytdb0b	144	45	24	24	CD
cord-347000-zxytdb0b	144	46	,	,	,
cord-347000-zxytdb0b	144	47	compared	compare	VBN
cord-347000-zxytdb0b	144	48	with	with	IN
cord-347000-zxytdb0b	144	49	the	the	DT
cord-347000-zxytdb0b	144	50	normal	normal	JJ
cord-347000-zxytdb0b	144	51	rates	rate	NNS
cord-347000-zxytdb0b	144	52	of	of	IN
cord-347000-zxytdb0b	144	53	1Â	1â	CD
cord-347000-zxytdb0b	144	54	10	10	CD
cord-347000-zxytdb0b	144	55	28	28	CD
cord-347000-zxytdb0b	144	56	to	to	TO
cord-347000-zxytdb0b	144	57	10	10	CD
cord-347000-zxytdb0b	144	58	27	27	CD
cord-347000-zxytdb0b	144	59	.	.	.
cord-347000-zxytdb0b	145	1	One	one	CD
cord-347000-zxytdb0b	145	2	study	study	NN
cord-347000-zxytdb0b	145	3	showed	show	VBD
cord-347000-zxytdb0b	145	4	hypermutators	hypermutator	NNS
cord-347000-zxytdb0b	145	5	in	in	IN
cord-347000-zxytdb0b	145	6	37	37	CD
cord-347000-zxytdb0b	145	7	%	%	NN
cord-347000-zxytdb0b	145	8	of	of	IN
cord-347000-zxytdb0b	145	9	CF	cf	NN
cord-347000-zxytdb0b	145	10	patients	patient	NNS
cord-347000-zxytdb0b	145	11	with	with	IN
cord-347000-zxytdb0b	145	12	chronic	chronic	JJ
cord-347000-zxytdb0b	145	13	infection	infection	NN
cord-347000-zxytdb0b	145	14	with	with	IN
cord-347000-zxytdb0b	145	15	P.	P.	NNP
cord-347000-zxytdb0b	145	16	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	145	17	.	.	.
cord-347000-zxytdb0b	146	1	32	32	CD
cord-347000-zxytdb0b	147	1	This	this	DT
cord-347000-zxytdb0b	147	2	was	be	VBD
cord-347000-zxytdb0b	147	3	the	the	DT
cord-347000-zxytdb0b	147	4	highest	high	JJS
cord-347000-zxytdb0b	147	5	prevalence	prevalence	NN
cord-347000-zxytdb0b	147	6	described	describe	VBN
cord-347000-zxytdb0b	147	7	in	in	IN
cord-347000-zxytdb0b	147	8	a	a	DT
cord-347000-zxytdb0b	147	9	natural	natural	JJ
cord-347000-zxytdb0b	147	10	system	system	NN
cord-347000-zxytdb0b	147	11	.	.	.
cord-347000-zxytdb0b	148	1	Since	since	IN
cord-347000-zxytdb0b	148	2	then	then	RB
cord-347000-zxytdb0b	148	3	hypermutators	hypermutator	NNS
cord-347000-zxytdb0b	148	4	have	have	VBP
cord-347000-zxytdb0b	148	5	been	be	VBN
cord-347000-zxytdb0b	148	6	shown	show	VBN
cord-347000-zxytdb0b	148	7	in	in	IN
cord-347000-zxytdb0b	148	8	other	other	JJ
cord-347000-zxytdb0b	148	9	chronic	chronic	JJ
cord-347000-zxytdb0b	148	10	lung	lung	NN
cord-347000-zxytdb0b	148	11	diseases	disease	NNS
cord-347000-zxytdb0b	148	12	.	.	.
cord-347000-zxytdb0b	149	1	33	33	CD
cord-347000-zxytdb0b	150	1	Hypermutator	Hypermutator	NNP
cord-347000-zxytdb0b	150	2	strains	strain	NNS
cord-347000-zxytdb0b	150	3	were	be	VBD
cord-347000-zxytdb0b	150	4	found	find	VBN
cord-347000-zxytdb0b	150	5	amongst	amongst	IN
cord-347000-zxytdb0b	150	6	isolates	isolate	NNS
cord-347000-zxytdb0b	150	7	of	of	IN
cord-347000-zxytdb0b	150	8	P.	P.	NNP
cord-347000-zxytdb0b	150	9	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	150	10	early	early	RB
cord-347000-zxytdb0b	150	11	in	in	IN
cord-347000-zxytdb0b	150	12	infection	infection	NN
cord-347000-zxytdb0b	150	13	suggesting	suggest	VBG
cord-347000-zxytdb0b	150	14	that	that	IN
cord-347000-zxytdb0b	150	15	they	-PRON-	PRP
cord-347000-zxytdb0b	150	16	may	may	MD
cord-347000-zxytdb0b	150	17	have	have	VB
cord-347000-zxytdb0b	150	18	an	an	DT
cord-347000-zxytdb0b	150	19	advantage	advantage	NN
cord-347000-zxytdb0b	150	20	in	in	IN
cord-347000-zxytdb0b	150	21	initiating	initiate	VBG
cord-347000-zxytdb0b	150	22	infection	infection	NN
cord-347000-zxytdb0b	150	23	as	as	RB
cord-347000-zxytdb0b	150	24	well	well	RB
cord-347000-zxytdb0b	150	25	as	as	IN
cord-347000-zxytdb0b	150	26	in	in	IN
cord-347000-zxytdb0b	150	27	chronic	chronic	JJ
cord-347000-zxytdb0b	150	28	infection	infection	NN
cord-347000-zxytdb0b	150	29	,	,	,
cord-347000-zxytdb0b	150	30	however	however	RB
cord-347000-zxytdb0b	150	31	they	-PRON-	PRP
cord-347000-zxytdb0b	150	32	were	be	VBD
cord-347000-zxytdb0b	150	33	infrequent	infrequent	JJ
cord-347000-zxytdb0b	150	34	.	.	.
cord-347000-zxytdb0b	151	1	34	34	CD
cord-347000-zxytdb0b	152	1	It	-PRON-	PRP
cord-347000-zxytdb0b	152	2	was	be	VBD
cord-347000-zxytdb0b	152	3	questioned	question	VBN
cord-347000-zxytdb0b	152	4	whether	whether	IN
cord-347000-zxytdb0b	152	5	mutator	mutator	NN
cord-347000-zxytdb0b	152	6	strains	strain	NNS
cord-347000-zxytdb0b	152	7	would	would	MD
cord-347000-zxytdb0b	152	8	be	be	VB
cord-347000-zxytdb0b	152	9	at	at	IN
cord-347000-zxytdb0b	152	10	a	a	DT
cord-347000-zxytdb0b	152	11	disadvantage	disadvantage	NN
cord-347000-zxytdb0b	152	12	because	because	IN
cord-347000-zxytdb0b	152	13	of	of	IN
cord-347000-zxytdb0b	152	14	the	the	DT
cord-347000-zxytdb0b	152	15	high	high	JJ
cord-347000-zxytdb0b	152	16	rate	rate	NN
cord-347000-zxytdb0b	152	17	of	of	IN
cord-347000-zxytdb0b	152	18	damaging	damaging	JJ
cord-347000-zxytdb0b	152	19	spontaneous	spontaneous	JJ
cord-347000-zxytdb0b	152	20	mutations	mutation	NNS
cord-347000-zxytdb0b	152	21	.	.	.
cord-347000-zxytdb0b	153	1	However	however	RB
cord-347000-zxytdb0b	153	2	,	,	,
cord-347000-zxytdb0b	153	3	their	-PRON-	PRP$
cord-347000-zxytdb0b	153	4	ability	ability	NN
cord-347000-zxytdb0b	153	5	to	to	TO
cord-347000-zxytdb0b	153	6	rapidly	rapidly	RB
cord-347000-zxytdb0b	153	7	adapt	adapt	VB
cord-347000-zxytdb0b	153	8	to	to	IN
cord-347000-zxytdb0b	153	9	a	a	DT
cord-347000-zxytdb0b	153	10	changing	change	VBG
cord-347000-zxytdb0b	153	11	environment	environment	NN
cord-347000-zxytdb0b	153	12	becomes	become	VBZ
cord-347000-zxytdb0b	153	13	an	an	DT
cord-347000-zxytdb0b	153	14	advantage	advantage	NN
cord-347000-zxytdb0b	153	15	in	in	IN
cord-347000-zxytdb0b	153	16	an	an	DT
cord-347000-zxytdb0b	153	17	ecological	ecological	JJ
cord-347000-zxytdb0b	153	18	niche	niche	NN
cord-347000-zxytdb0b	153	19	repeatedly	repeatedly	RB
cord-347000-zxytdb0b	153	20	exposed	expose	VBN
cord-347000-zxytdb0b	153	21	to	to	IN
cord-347000-zxytdb0b	153	22	antibiotics	antibiotic	NNS
cord-347000-zxytdb0b	153	23	.	.	.
cord-347000-zxytdb0b	154	1	In	in	IN
cord-347000-zxytdb0b	154	2	the	the	DT
cord-347000-zxytdb0b	154	3	large	large	JJ
cord-347000-zxytdb0b	154	4	population	population	NN
cord-347000-zxytdb0b	154	5	of	of	IN
cord-347000-zxytdb0b	154	6	bacteria	bacteria	NNS
cord-347000-zxytdb0b	154	7	in	in	IN
cord-347000-zxytdb0b	154	8	the	the	DT
cord-347000-zxytdb0b	154	9	CF	CF	NNP
cord-347000-zxytdb0b	154	10	lung	lung	NN
cord-347000-zxytdb0b	154	11	,	,	,
cord-347000-zxytdb0b	154	12	an	an	DT
cord-347000-zxytdb0b	154	13	organism	organism	NN
cord-347000-zxytdb0b	154	14	with	with	IN
cord-347000-zxytdb0b	154	15	a	a	DT
cord-347000-zxytdb0b	154	16	mutation	mutation	NN
cord-347000-zxytdb0b	154	17	for	for	IN
cord-347000-zxytdb0b	154	18	antibiotic	antibiotic	JJ
cord-347000-zxytdb0b	154	19	resistance	resistance	NN
cord-347000-zxytdb0b	154	20	may	may	MD
cord-347000-zxytdb0b	154	21	be	be	VB
cord-347000-zxytdb0b	154	22	present	present	JJ
cord-347000-zxytdb0b	154	23	even	even	RB
cord-347000-zxytdb0b	154	24	before	before	IN
cord-347000-zxytdb0b	154	25	the	the	DT
cord-347000-zxytdb0b	154	26	antibiotic	antibiotic	NN
cord-347000-zxytdb0b	154	27	is	be	VBZ
cord-347000-zxytdb0b	154	28	given	give	VBN
cord-347000-zxytdb0b	154	29	.	.	.
cord-347000-zxytdb0b	155	1	It	-PRON-	PRP
cord-347000-zxytdb0b	155	2	has	have	VBZ
cord-347000-zxytdb0b	155	3	been	be	VBN
cord-347000-zxytdb0b	155	4	practice	practice	NN
cord-347000-zxytdb0b	155	5	in	in	IN
cord-347000-zxytdb0b	155	6	CF	CF	NNP
cord-347000-zxytdb0b	155	7	to	to	TO
cord-347000-zxytdb0b	155	8	give	give	VB
cord-347000-zxytdb0b	155	9	two	two	CD
cord-347000-zxytdb0b	155	10	anti	anti	JJ
cord-347000-zxytdb0b	155	11	-	-	JJ
cord-347000-zxytdb0b	155	12	pseudomonal	pseudomonal	JJ
cord-347000-zxytdb0b	155	13	antibiotics	antibiotic	NNS
cord-347000-zxytdb0b	155	14	to	to	TO
cord-347000-zxytdb0b	155	15	reduce	reduce	VB
cord-347000-zxytdb0b	155	16	the	the	DT
cord-347000-zxytdb0b	155	17	emergence	emergence	NN
cord-347000-zxytdb0b	155	18	of	of	IN
cord-347000-zxytdb0b	155	19	resistant	resistant	JJ
cord-347000-zxytdb0b	155	20	strains	strain	NNS
cord-347000-zxytdb0b	155	21	.	.	.
cord-347000-zxytdb0b	156	1	The	the	DT
cord-347000-zxytdb0b	156	2	recent	recent	JJ
cord-347000-zxytdb0b	156	3	observation	observation	NN
cord-347000-zxytdb0b	156	4	of	of	IN
cord-347000-zxytdb0b	156	5	hypermutators	hypermutators	NNP
cord-347000-zxytdb0b	156	6	in	in	IN
cord-347000-zxytdb0b	156	7	CF	CF	NNP
cord-347000-zxytdb0b	156	8	shows	show	VBZ
cord-347000-zxytdb0b	156	9	the	the	DT
cord-347000-zxytdb0b	156	10	potential	potential	JJ
cord-347000-zxytdb0b	156	11	importance	importance	NN
cord-347000-zxytdb0b	156	12	of	of	IN
cord-347000-zxytdb0b	156	13	that	that	DT
cord-347000-zxytdb0b	156	14	recommendation	recommendation	NN
cord-347000-zxytdb0b	156	15	.	.	.
cord-347000-zxytdb0b	157	1	In	in	IN
cord-347000-zxytdb0b	157	2	common	common	JJ
cord-347000-zxytdb0b	157	3	with	with	IN
cord-347000-zxytdb0b	157	4	other	other	JJ
cord-347000-zxytdb0b	157	5	bacteria	bacteria	NNS
cord-347000-zxytdb0b	157	6	seen	see	VBN
cord-347000-zxytdb0b	157	7	in	in	IN
cord-347000-zxytdb0b	157	8	CF	CF	NNP
cord-347000-zxytdb0b	157	9	,	,	,
cord-347000-zxytdb0b	157	10	some	some	DT
cord-347000-zxytdb0b	157	11	P.	p.	NN
cord-347000-zxytdb0b	157	12	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	157	13	form	form	NN
cord-347000-zxytdb0b	157	14	biofilms	biofilm	NNS
cord-347000-zxytdb0b	157	15	in	in	IN
cord-347000-zxytdb0b	157	16	vitro	vitro	FW
cord-347000-zxytdb0b	157	17	and	and	CC
cord-347000-zxytdb0b	157	18	can	can	MD
cord-347000-zxytdb0b	157	19	be	be	VB
cord-347000-zxytdb0b	157	20	observed	observe	VBN
cord-347000-zxytdb0b	157	21	in	in	IN
cord-347000-zxytdb0b	157	22	biofilm	biofilm	NN
cord-347000-zxytdb0b	157	23	-	-	HYPH
cord-347000-zxytdb0b	157	24	like	like	JJ
cord-347000-zxytdb0b	157	25	aggregates	aggregate	NNS
cord-347000-zxytdb0b	157	26	in	in	IN
cord-347000-zxytdb0b	157	27	expectorated	expectorated	JJ
cord-347000-zxytdb0b	157	28	sputum	sputum	NN
cord-347000-zxytdb0b	157	29	.	.	.
cord-347000-zxytdb0b	158	1	Biofilms	Biofilms	NNP
cord-347000-zxytdb0b	158	2	are	be	VBP
cord-347000-zxytdb0b	158	3	communities	community	NNS
cord-347000-zxytdb0b	158	4	of	of	IN
cord-347000-zxytdb0b	158	5	bacteria	bacteria	NNS
cord-347000-zxytdb0b	158	6	within	within	IN
cord-347000-zxytdb0b	158	7	an	an	DT
cord-347000-zxytdb0b	158	8	acellular	acellular	JJ
cord-347000-zxytdb0b	158	9	matrix	matrix	NN
cord-347000-zxytdb0b	158	10	,	,	,
cord-347000-zxytdb0b	158	11	usually	usually	RB
cord-347000-zxytdb0b	158	12	attached	attach	VBN
cord-347000-zxytdb0b	158	13	to	to	IN
cord-347000-zxytdb0b	158	14	a	a	DT
cord-347000-zxytdb0b	158	15	surface	surface	NN
cord-347000-zxytdb0b	158	16	-	-	HYPH
cord-347000-zxytdb0b	158	17	in	in	NN
cord-347000-zxytdb0b	158	18	CF	CF	NNP
cord-347000-zxytdb0b	158	19	,	,	,
cord-347000-zxytdb0b	158	20	the	the	DT
cord-347000-zxytdb0b	158	21	respiratory	respiratory	JJ
cord-347000-zxytdb0b	158	22	epithelium	epithelium	NN
cord-347000-zxytdb0b	158	23	.	.	.
cord-347000-zxytdb0b	159	1	In	in	IN
cord-347000-zxytdb0b	159	2	the	the	DT
cord-347000-zxytdb0b	159	3	patient	patient	NN
cord-347000-zxytdb0b	159	4	,	,	,
cord-347000-zxytdb0b	159	5	biofilms	biofilm	NNS
cord-347000-zxytdb0b	159	6	may	may	MD
cord-347000-zxytdb0b	159	7	also	also	RB
cord-347000-zxytdb0b	159	8	contain	contain	VB
cord-347000-zxytdb0b	159	9	other	other	JJ
cord-347000-zxytdb0b	159	10	species	specie	NNS
cord-347000-zxytdb0b	159	11	of	of	IN
cord-347000-zxytdb0b	159	12	bacteria	bacteria	NNS
cord-347000-zxytdb0b	159	13	and	and	CC
cord-347000-zxytdb0b	159	14	host	host	NN
cord-347000-zxytdb0b	159	15	-	-	HYPH
cord-347000-zxytdb0b	159	16	derived	derive	VBN
cord-347000-zxytdb0b	159	17	products	product	NNS
cord-347000-zxytdb0b	159	18	.	.	.
cord-347000-zxytdb0b	160	1	Bacteria	Bacteria	NNS
cord-347000-zxytdb0b	160	2	in	in	IN
cord-347000-zxytdb0b	160	3	biofilms	biofilm	NNS
cord-347000-zxytdb0b	160	4	are	be	VBP
cord-347000-zxytdb0b	160	5	difficult	difficult	JJ
cord-347000-zxytdb0b	160	6	to	to	TO
cord-347000-zxytdb0b	160	7	eradicate	eradicate	VB
cord-347000-zxytdb0b	160	8	as	as	IN
cord-347000-zxytdb0b	160	9	they	-PRON-	PRP
cord-347000-zxytdb0b	160	10	can	can	MD
cord-347000-zxytdb0b	160	11	resist	resist	VB
cord-347000-zxytdb0b	160	12	the	the	DT
cord-347000-zxytdb0b	160	13	host	host	NN
cord-347000-zxytdb0b	160	14	immune	immune	JJ
cord-347000-zxytdb0b	160	15	system	system	NN
cord-347000-zxytdb0b	160	16	and	and	CC
cord-347000-zxytdb0b	160	17	are	be	VBP
cord-347000-zxytdb0b	160	18	more	more	RBR
cord-347000-zxytdb0b	160	19	antibiotic	antibiotic	JJ
cord-347000-zxytdb0b	160	20	resistant	resistant	JJ
cord-347000-zxytdb0b	160	21	by	by	IN
cord-347000-zxytdb0b	160	22	a	a	DT
cord-347000-zxytdb0b	160	23	variety	variety	NN
cord-347000-zxytdb0b	160	24	of	of	IN
cord-347000-zxytdb0b	160	25	mechanisms	mechanism	NNS
cord-347000-zxytdb0b	160	26	.	.	.
cord-347000-zxytdb0b	161	1	Antibiotics	antibiotic	NNS
cord-347000-zxytdb0b	161	2	may	may	MD
cord-347000-zxytdb0b	161	3	bind	bind	VB
cord-347000-zxytdb0b	161	4	to	to	IN
cord-347000-zxytdb0b	161	5	the	the	DT
cord-347000-zxytdb0b	161	6	extracellular	extracellular	JJ
cord-347000-zxytdb0b	161	7	matrix	matrix	NN
cord-347000-zxytdb0b	161	8	or	or	CC
cord-347000-zxytdb0b	161	9	have	have	VBP
cord-347000-zxytdb0b	161	10	reduced	reduce	VBN
cord-347000-zxytdb0b	161	11	activity	activity	NN
cord-347000-zxytdb0b	161	12	in	in	IN
cord-347000-zxytdb0b	161	13	areas	area	NNS
cord-347000-zxytdb0b	161	14	of	of	IN
cord-347000-zxytdb0b	161	15	poor	poor	JJ
cord-347000-zxytdb0b	161	16	oxygenation	oxygenation	NN
cord-347000-zxytdb0b	161	17	or	or	CC
cord-347000-zxytdb0b	162	1	low	low	JJ
cord-347000-zxytdb0b	162	2	pH.	pH.	NNP
cord-347000-zxytdb0b	162	3	Also	also	RB
cord-347000-zxytdb0b	162	4	the	the	DT
cord-347000-zxytdb0b	162	5	bacteria	bacteria	NNS
cord-347000-zxytdb0b	162	6	in	in	IN
cord-347000-zxytdb0b	162	7	a	a	DT
cord-347000-zxytdb0b	162	8	biofilm	biofilm	NN
cord-347000-zxytdb0b	162	9	live	live	VBP
cord-347000-zxytdb0b	162	10	in	in	IN
cord-347000-zxytdb0b	162	11	a	a	DT
cord-347000-zxytdb0b	162	12	gradient	gradient	NN
cord-347000-zxytdb0b	162	13	of	of	IN
cord-347000-zxytdb0b	162	14	oxygen	oxygen	NN
cord-347000-zxytdb0b	162	15	,	,	,
cord-347000-zxytdb0b	162	16	nutrients	nutrient	NNS
cord-347000-zxytdb0b	162	17	and	and	CC
cord-347000-zxytdb0b	162	18	metabolites	metabolite	NNS
cord-347000-zxytdb0b	162	19	.	.	.
cord-347000-zxytdb0b	163	1	They	-PRON-	PRP
cord-347000-zxytdb0b	163	2	are	be	VBP
cord-347000-zxytdb0b	163	3	therefore	therefore	RB
cord-347000-zxytdb0b	163	4	diverse	diverse	JJ
cord-347000-zxytdb0b	163	5	,	,	,
cord-347000-zxytdb0b	163	6	having	have	VBG
cord-347000-zxytdb0b	163	7	adapted	adapt	VBN
cord-347000-zxytdb0b	163	8	to	to	IN
cord-347000-zxytdb0b	163	9	the	the	DT
cord-347000-zxytdb0b	163	10	different	different	JJ
cord-347000-zxytdb0b	163	11	micro	micro	NNS
cord-347000-zxytdb0b	163	12	-	-	NNS
cord-347000-zxytdb0b	163	13	environments	environment	NNS
cord-347000-zxytdb0b	163	14	.	.	.
cord-347000-zxytdb0b	164	1	The	the	DT
cord-347000-zxytdb0b	164	2	growth	growth	NN
cord-347000-zxytdb0b	164	3	phase	phase	NN
cord-347000-zxytdb0b	164	4	(	(	-LRB-
cord-347000-zxytdb0b	164	5	actively	actively	RB
cord-347000-zxytdb0b	164	6	dividing	divide	VBG
cord-347000-zxytdb0b	164	7	or	or	CC
cord-347000-zxytdb0b	164	8	dormant	dormant	JJ
cord-347000-zxytdb0b	164	9	)	)	-RRB-
cord-347000-zxytdb0b	164	10	may	may	MD
cord-347000-zxytdb0b	164	11	affect	affect	VB
cord-347000-zxytdb0b	164	12	their	-PRON-	PRP$
cord-347000-zxytdb0b	164	13	susceptibility	susceptibility	NN
cord-347000-zxytdb0b	164	14	to	to	IN
cord-347000-zxytdb0b	164	15	some	some	DT
cord-347000-zxytdb0b	164	16	antibiotics	antibiotic	NNS
cord-347000-zxytdb0b	164	17	.	.	.
cord-347000-zxytdb0b	165	1	35	35	CD
cord-347000-zxytdb0b	166	1	The	the	DT
cord-347000-zxytdb0b	166	2	variability	variability	NN
cord-347000-zxytdb0b	166	3	in	in	IN
cord-347000-zxytdb0b	166	4	antibiotic	antibiotic	JJ
cord-347000-zxytdb0b	166	5	susceptibility	susceptibility	NN
cord-347000-zxytdb0b	166	6	seen	see	VBN
cord-347000-zxytdb0b	166	7	in	in	IN
cord-347000-zxytdb0b	166	8	the	the	DT
cord-347000-zxytdb0b	166	9	population	population	NN
cord-347000-zxytdb0b	166	10	of	of	IN
cord-347000-zxytdb0b	166	11	bacteria	bacteria	NNS
cord-347000-zxytdb0b	166	12	cultured	culture	VBN
cord-347000-zxytdb0b	166	13	from	from	IN
cord-347000-zxytdb0b	166	14	a	a	DT
cord-347000-zxytdb0b	166	15	single	single	JJ
cord-347000-zxytdb0b	166	16	sputum	sputum	NN
cord-347000-zxytdb0b	166	17	under	under	IN
cord-347000-zxytdb0b	166	18	the	the	DT
cord-347000-zxytdb0b	166	19	same	same	JJ
cord-347000-zxytdb0b	166	20	in	in	IN
cord-347000-zxytdb0b	166	21	vitro	vitro	FW
cord-347000-zxytdb0b	166	22	conditions	condition	NNS
cord-347000-zxytdb0b	166	23	may	may	MD
cord-347000-zxytdb0b	166	24	be	be	VB
cord-347000-zxytdb0b	166	25	because	because	IN
cord-347000-zxytdb0b	166	26	bacteria	bacteria	NNS
cord-347000-zxytdb0b	166	27	are	be	VBP
cord-347000-zxytdb0b	166	28	present	present	JJ
cord-347000-zxytdb0b	166	29	in	in	IN
cord-347000-zxytdb0b	166	30	biofilm	biofilm	NN
cord-347000-zxytdb0b	166	31	fragments	fragment	NNS
cord-347000-zxytdb0b	166	32	in	in	IN
cord-347000-zxytdb0b	166	33	the	the	DT
cord-347000-zxytdb0b	166	34	sputum	sputum	NN
cord-347000-zxytdb0b	166	35	.	.	.
cord-347000-zxytdb0b	167	1	These	these	DT
cord-347000-zxytdb0b	167	2	organisms	organism	NNS
cord-347000-zxytdb0b	167	3	may	may	MD
cord-347000-zxytdb0b	167	4	have	have	VB
cord-347000-zxytdb0b	167	5	adapted	adapt	VBN
cord-347000-zxytdb0b	167	6	to	to	IN
cord-347000-zxytdb0b	167	7	a	a	DT
cord-347000-zxytdb0b	167	8	range	range	NN
cord-347000-zxytdb0b	167	9	of	of	IN
cord-347000-zxytdb0b	167	10	different	different	JJ
cord-347000-zxytdb0b	167	11	active	active	JJ
cord-347000-zxytdb0b	167	12	concentrations	concentration	NNS
cord-347000-zxytdb0b	167	13	of	of	IN
cord-347000-zxytdb0b	167	14	antibiotic	antibiotic	NN
cord-347000-zxytdb0b	167	15	encountered	encounter	VBN
cord-347000-zxytdb0b	167	16	in	in	IN
cord-347000-zxytdb0b	167	17	different	different	JJ
cord-347000-zxytdb0b	167	18	levels	level	NNS
cord-347000-zxytdb0b	167	19	of	of	IN
cord-347000-zxytdb0b	167	20	the	the	DT
cord-347000-zxytdb0b	167	21	biofilm	biofilm	NN
cord-347000-zxytdb0b	167	22	.	.	.
cord-347000-zxytdb0b	168	1	Concern	concern	NN
cord-347000-zxytdb0b	168	2	that	that	IN
cord-347000-zxytdb0b	168	3	laboratory	laboratory	NN
cord-347000-zxytdb0b	168	4	methods	method	NNS
cord-347000-zxytdb0b	168	5	developed	develop	VBN
cord-347000-zxytdb0b	168	6	to	to	TO
cord-347000-zxytdb0b	168	7	measure	measure	VB
cord-347000-zxytdb0b	168	8	the	the	DT
cord-347000-zxytdb0b	168	9	antibiotic	antibiotic	JJ
cord-347000-zxytdb0b	168	10	susceptibility	susceptibility	NN
cord-347000-zxytdb0b	168	11	of	of	IN
cord-347000-zxytdb0b	168	12	planktonic	planktonic	JJ
cord-347000-zxytdb0b	168	13	bacteria	bacteria	NNS
cord-347000-zxytdb0b	168	14	causing	cause	VBG
cord-347000-zxytdb0b	168	15	acute	acute	JJ
cord-347000-zxytdb0b	168	16	infections	infection	NNS
cord-347000-zxytdb0b	168	17	may	may	MD
cord-347000-zxytdb0b	168	18	not	not	RB
cord-347000-zxytdb0b	168	19	be	be	VB
cord-347000-zxytdb0b	168	20	relevant	relevant	JJ
cord-347000-zxytdb0b	168	21	to	to	IN
cord-347000-zxytdb0b	168	22	CF	CF	NNP
cord-347000-zxytdb0b	168	23	has	have	VBZ
cord-347000-zxytdb0b	168	24	led	lead	VBN
cord-347000-zxytdb0b	168	25	to	to	IN
cord-347000-zxytdb0b	168	26	development	development	NN
cord-347000-zxytdb0b	168	27	of	of	IN
cord-347000-zxytdb0b	168	28	methods	method	NNS
cord-347000-zxytdb0b	168	29	to	to	TO
cord-347000-zxytdb0b	168	30	test	test	VB
cord-347000-zxytdb0b	168	31	antibiotic	antibiotic	JJ
cord-347000-zxytdb0b	168	32	susceptibility	susceptibility	NN
cord-347000-zxytdb0b	168	33	in	in	IN
cord-347000-zxytdb0b	168	34	a	a	DT
cord-347000-zxytdb0b	168	35	biofilm	biofilm	NN
cord-347000-zxytdb0b	168	36	.	.	.
cord-347000-zxytdb0b	169	1	Evaluation	evaluation	NN
cord-347000-zxytdb0b	169	2	of	of	IN
cord-347000-zxytdb0b	169	3	one	one	CD
cord-347000-zxytdb0b	169	4	method	method	NN
cord-347000-zxytdb0b	169	5	to	to	TO
cord-347000-zxytdb0b	169	6	determine	determine	VB
cord-347000-zxytdb0b	169	7	the	the	DT
cord-347000-zxytdb0b	169	8	optimum	optimum	JJ
cord-347000-zxytdb0b	169	9	antibiotics	antibiotic	NNS
cord-347000-zxytdb0b	169	10	to	to	TO
cord-347000-zxytdb0b	169	11	clear	clear	VB
cord-347000-zxytdb0b	169	12	chronic	chronic	JJ
cord-347000-zxytdb0b	169	13	infection	infection	NN
cord-347000-zxytdb0b	169	14	is	be	VBZ
cord-347000-zxytdb0b	169	15	in	in	IN
cord-347000-zxytdb0b	169	16	progress	progress	NN
cord-347000-zxytdb0b	169	17	.	.	.
cord-347000-zxytdb0b	170	1	36	36	CD
cord-347000-zxytdb0b	171	1	A	a	DT
cord-347000-zxytdb0b	171	2	recent	recent	JJ
cord-347000-zxytdb0b	171	3	study	study	NN
cord-347000-zxytdb0b	171	4	using	use	VBG
cord-347000-zxytdb0b	171	5	whole	whole	JJ
cord-347000-zxytdb0b	171	6	genome	genome	NN
cord-347000-zxytdb0b	171	7	analysis	analysis	NN
cord-347000-zxytdb0b	171	8	showed	show	VBD
cord-347000-zxytdb0b	171	9	an	an	DT
cord-347000-zxytdb0b	171	10	accumulation	accumulation	NN
cord-347000-zxytdb0b	171	11	of	of	IN
cord-347000-zxytdb0b	171	12	mutations	mutation	NNS
cord-347000-zxytdb0b	171	13	in	in	IN
cord-347000-zxytdb0b	171	14	68	68	CD
cord-347000-zxytdb0b	171	15	genes	gene	NNS
cord-347000-zxytdb0b	171	16	of	of	IN
cord-347000-zxytdb0b	171	17	P.	P.	NNP
cord-347000-zxytdb0b	171	18	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	171	19	over	over	IN
cord-347000-zxytdb0b	171	20	8	8	CD
cord-347000-zxytdb0b	171	21	years	year	NNS
cord-347000-zxytdb0b	171	22	in	in	IN
cord-347000-zxytdb0b	171	23	a	a	DT
cord-347000-zxytdb0b	171	24	patient	patient	NN
cord-347000-zxytdb0b	171	25	with	with	IN
cord-347000-zxytdb0b	171	26	CF	CF	NNP
cord-347000-zxytdb0b	171	27	.	.	.
cord-347000-zxytdb0b	172	1	37	37	CD
cord-347000-zxytdb0b	173	1	This	this	DT
cord-347000-zxytdb0b	173	2	evolutionary	evolutionary	JJ
cord-347000-zxytdb0b	173	3	divergence	divergence	NN
cord-347000-zxytdb0b	173	4	was	be	VBD
cord-347000-zxytdb0b	173	5	thought	think	VBN
cord-347000-zxytdb0b	173	6	to	to	TO
cord-347000-zxytdb0b	173	7	favour	favour	VB
cord-347000-zxytdb0b	173	8	adaptation	adaptation	NN
cord-347000-zxytdb0b	173	9	.	.	.
cord-347000-zxytdb0b	174	1	Early	early	JJ
cord-347000-zxytdb0b	174	2	and	and	CC
cord-347000-zxytdb0b	174	3	late	late	JJ
cord-347000-zxytdb0b	174	4	isolates	isolate	NNS
cord-347000-zxytdb0b	174	5	of	of	IN
cord-347000-zxytdb0b	174	6	P.	P.	NNP
cord-347000-zxytdb0b	174	7	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	174	8	from	from	IN
cord-347000-zxytdb0b	174	9	29	29	CD
cord-347000-zxytdb0b	174	10	patients	patient	NNS
cord-347000-zxytdb0b	174	11	were	be	VBD
cord-347000-zxytdb0b	174	12	compared	compare	VBN
cord-347000-zxytdb0b	174	13	to	to	TO
cord-347000-zxytdb0b	174	14	look	look	VB
cord-347000-zxytdb0b	174	15	at	at	IN
cord-347000-zxytdb0b	174	16	these	these	DT
cord-347000-zxytdb0b	174	17	genes	gene	NNS
cord-347000-zxytdb0b	174	18	.	.	.
cord-347000-zxytdb0b	175	1	One	one	CD
cord-347000-zxytdb0b	175	2	of	of	IN
cord-347000-zxytdb0b	175	3	the	the	DT
cord-347000-zxytdb0b	175	4	commonest	common	JJS
cord-347000-zxytdb0b	175	5	mutations	mutation	NNS
cord-347000-zxytdb0b	175	6	was	be	VBD
cord-347000-zxytdb0b	175	7	in	in	IN
cord-347000-zxytdb0b	175	8	las	las	NNP
cord-347000-zxytdb0b	175	9	R	R	NNP
cord-347000-zxytdb0b	175	10	,	,	,
cord-347000-zxytdb0b	175	11	the	the	DT
cord-347000-zxytdb0b	175	12	principle	principle	JJ
cord-347000-zxytdb0b	175	13	QS	QS	NNP
cord-347000-zxytdb0b	175	14	regulator	regulator	NN
cord-347000-zxytdb0b	175	15	in	in	IN
cord-347000-zxytdb0b	175	16	P.	P.	NNP
cord-347000-zxytdb0b	175	17	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	175	18	.	.	.
cord-347000-zxytdb0b	176	1	This	this	DT
cord-347000-zxytdb0b	176	2	interferes	interfere	VBZ
cord-347000-zxytdb0b	176	3	with	with	IN
cord-347000-zxytdb0b	176	4	many	many	JJ
cord-347000-zxytdb0b	176	5	pathogenicity	pathogenicity	NN
cord-347000-zxytdb0b	176	6	factors	factor	NNS
cord-347000-zxytdb0b	176	7	including	include	VBG
cord-347000-zxytdb0b	176	8	biofilm	biofilm	NN
cord-347000-zxytdb0b	176	9	formation	formation	NN
cord-347000-zxytdb0b	176	10	.	.	.
cord-347000-zxytdb0b	177	1	This	this	DT
cord-347000-zxytdb0b	177	2	is	be	VBZ
cord-347000-zxytdb0b	177	3	difficult	difficult	JJ
cord-347000-zxytdb0b	177	4	to	to	TO
cord-347000-zxytdb0b	177	5	reconcile	reconcile	VB
cord-347000-zxytdb0b	177	6	with	with	IN
cord-347000-zxytdb0b	177	7	the	the	DT
cord-347000-zxytdb0b	177	8	proposed	propose	VBN
cord-347000-zxytdb0b	177	9	importance	importance	NN
cord-347000-zxytdb0b	177	10	of	of	IN
cord-347000-zxytdb0b	177	11	biofilms	biofilm	NNS
cord-347000-zxytdb0b	177	12	in	in	IN
cord-347000-zxytdb0b	177	13	persistence	persistence	NN
cord-347000-zxytdb0b	177	14	of	of	IN
cord-347000-zxytdb0b	177	15	infection	infection	NN
cord-347000-zxytdb0b	177	16	.	.	.
cord-347000-zxytdb0b	178	1	Other	other	JJ
cord-347000-zxytdb0b	178	2	genes	gene	NNS
cord-347000-zxytdb0b	178	3	commonly	commonly	RB
cord-347000-zxytdb0b	178	4	mutated	mutate	VBN
cord-347000-zxytdb0b	178	5	after	after	IN
cord-347000-zxytdb0b	178	6	chronic	chronic	JJ
cord-347000-zxytdb0b	178	7	colonization	colonization	NN
cord-347000-zxytdb0b	178	8	are	be	VBP
cord-347000-zxytdb0b	178	9	also	also	RB
cord-347000-zxytdb0b	178	10	involved	involve	VBN
cord-347000-zxytdb0b	178	11	in	in	IN
cord-347000-zxytdb0b	178	12	pathogenicity	pathogenicity	NN
cord-347000-zxytdb0b	179	1	e.g.	e.g.	RB
cord-347000-zxytdb0b	179	2	exo	exo	NNP
cord-347000-zxytdb0b	179	3	A	A	NNP
cord-347000-zxytdb0b	179	4	,	,	,
cord-347000-zxytdb0b	179	5	the	the	DT
cord-347000-zxytdb0b	179	6	regulator	regulator	NN
cord-347000-zxytdb0b	179	7	of	of	IN
cord-347000-zxytdb0b	179	8	type	type	NN
cord-347000-zxytdb0b	179	9	III	iii	CD
cord-347000-zxytdb0b	179	10	secretion	secretion	NN
cord-347000-zxytdb0b	179	11	and	and	CC
cord-347000-zxytdb0b	179	12	antibiotic	antibiotic	JJ
cord-347000-zxytdb0b	179	13	resistance	resistance	NN
cord-347000-zxytdb0b	179	14	(	(	-LRB-
cord-347000-zxytdb0b	179	15	genes	gene	NNS
cord-347000-zxytdb0b	179	16	coding	code	VBG
cord-347000-zxytdb0b	179	17	for	for	IN
cord-347000-zxytdb0b	179	18	components	component	NNS
cord-347000-zxytdb0b	179	19	of	of	IN
cord-347000-zxytdb0b	179	20	multi	multi	JJ
cord-347000-zxytdb0b	179	21	-	-	JJ
cord-347000-zxytdb0b	179	22	drug	drug	JJ
cord-347000-zxytdb0b	179	23	efflux	efflux	NN
cord-347000-zxytdb0b	179	24	pumps	pump	NNS
cord-347000-zxytdb0b	179	25	)	)	-RRB-
cord-347000-zxytdb0b	179	26	.	.	.
cord-347000-zxytdb0b	180	1	The	the	DT
cord-347000-zxytdb0b	180	2	picture	picture	NN
cord-347000-zxytdb0b	180	3	that	that	WDT
cord-347000-zxytdb0b	180	4	may	may	MD
cord-347000-zxytdb0b	180	5	be	be	VB
cord-347000-zxytdb0b	180	6	emerging	emerge	VBG
cord-347000-zxytdb0b	180	7	is	be	VBZ
cord-347000-zxytdb0b	180	8	therefore	therefore	RB
cord-347000-zxytdb0b	180	9	of	of	IN
cord-347000-zxytdb0b	180	10	an	an	DT
cord-347000-zxytdb0b	180	11	organism	organism	NN
cord-347000-zxytdb0b	180	12	with	with	IN
cord-347000-zxytdb0b	180	13	a	a	DT
cord-347000-zxytdb0b	180	14	great	great	JJ
cord-347000-zxytdb0b	180	15	ability	ability	NN
cord-347000-zxytdb0b	180	16	to	to	TO
cord-347000-zxytdb0b	180	17	adapt	adapt	VB
cord-347000-zxytdb0b	180	18	to	to	IN
cord-347000-zxytdb0b	180	19	its	-PRON-	PRP$
cord-347000-zxytdb0b	180	20	environment	environment	NN
cord-347000-zxytdb0b	180	21	that	that	WDT
cord-347000-zxytdb0b	180	22	becomes	become	VBZ
cord-347000-zxytdb0b	180	23	less	less	RBR
cord-347000-zxytdb0b	180	24	pathogenic	pathogenic	JJ
cord-347000-zxytdb0b	180	25	with	with	IN
cord-347000-zxytdb0b	180	26	time	time	NN
cord-347000-zxytdb0b	180	27	,	,	,
cord-347000-zxytdb0b	180	28	presumably	presumably	RB
cord-347000-zxytdb0b	180	29	in	in	IN
cord-347000-zxytdb0b	180	30	itself	-PRON-	PRP
cord-347000-zxytdb0b	180	31	a	a	DT
cord-347000-zxytdb0b	180	32	device	device	NN
cord-347000-zxytdb0b	180	33	for	for	IN
cord-347000-zxytdb0b	180	34	long	long	JJ
cord-347000-zxytdb0b	180	35	-	-	HYPH
cord-347000-zxytdb0b	180	36	term	term	NN
cord-347000-zxytdb0b	180	37	survival	survival	NN
cord-347000-zxytdb0b	180	38	in	in	IN
cord-347000-zxytdb0b	180	39	its	-PRON-	PRP$
cord-347000-zxytdb0b	180	40	host	host	NN
cord-347000-zxytdb0b	180	41	.	.	.
cord-347000-zxytdb0b	181	1	A	a	DT
cord-347000-zxytdb0b	181	2	recent	recent	JJ
cord-347000-zxytdb0b	181	3	study	study	NN
cord-347000-zxytdb0b	181	4	has	have	VBZ
cord-347000-zxytdb0b	181	5	shown	show	VBN
cord-347000-zxytdb0b	181	6	that	that	IN
cord-347000-zxytdb0b	181	7	antibiotic	antibiotic	JJ
cord-347000-zxytdb0b	181	8	-	-	HYPH
cord-347000-zxytdb0b	181	9	resistant	resistant	JJ
cord-347000-zxytdb0b	181	10	genes	gene	NNS
cord-347000-zxytdb0b	181	11	are	be	VBP
cord-347000-zxytdb0b	181	12	not	not	RB
cord-347000-zxytdb0b	181	13	over	over	RB
cord-347000-zxytdb0b	181	14	-	-	HYPH
cord-347000-zxytdb0b	181	15	represented	represent	VBN
cord-347000-zxytdb0b	181	16	in	in	IN
cord-347000-zxytdb0b	181	17	hypermutators	hypermutator	NNS
cord-347000-zxytdb0b	181	18	and	and	CC
cord-347000-zxytdb0b	181	19	that	that	IN
cord-347000-zxytdb0b	181	20	hypermutability	hypermutability	NN
cord-347000-zxytdb0b	181	21	may	may	MD
cord-347000-zxytdb0b	181	22	play	play	VB
cord-347000-zxytdb0b	181	23	an	an	DT
cord-347000-zxytdb0b	181	24	important	important	JJ
cord-347000-zxytdb0b	181	25	more	more	RBR
cord-347000-zxytdb0b	181	26	general	general	JJ
cord-347000-zxytdb0b	181	27	role	role	NN
cord-347000-zxytdb0b	181	28	in	in	IN
cord-347000-zxytdb0b	181	29	genome	genome	NN
cord-347000-zxytdb0b	181	30	evolution	evolution	NN
cord-347000-zxytdb0b	181	31	and	and	CC
cord-347000-zxytdb0b	181	32	adaptation	adaptation	NN
cord-347000-zxytdb0b	181	33	in	in	IN
cord-347000-zxytdb0b	181	34	the	the	DT
cord-347000-zxytdb0b	181	35	CF	cf	NN
cord-347000-zxytdb0b	181	36	lung	lung	NN
cord-347000-zxytdb0b	181	37	.	.	.
cord-347000-zxytdb0b	182	1	38	38	CD
cord-347000-zxytdb0b	182	2	Pseudomonas	Pseudomonas	NNP
cord-347000-zxytdb0b	182	3	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	182	4	and	and	CC
cord-347000-zxytdb0b	182	5	Burkholderia	Burkholderia	NNP
cord-347000-zxytdb0b	182	6	spp	spp	NNP
cord-347000-zxytdb0b	182	7	.	.	.
cord-347000-zxytdb0b	183	1	(	(	-LRB-
cord-347000-zxytdb0b	183	2	see	see	VB
cord-347000-zxytdb0b	183	3	below	below	RB
cord-347000-zxytdb0b	183	4	)	)	-RRB-
cord-347000-zxytdb0b	183	5	in	in	IN
cord-347000-zxytdb0b	183	6	CF	CF	NNP
cord-347000-zxytdb0b	183	7	have	have	VBP
cord-347000-zxytdb0b	183	8	a	a	DT
cord-347000-zxytdb0b	183	9	range	range	NN
cord-347000-zxytdb0b	183	10	of	of	IN
cord-347000-zxytdb0b	183	11	strategies	strategy	NNS
cord-347000-zxytdb0b	183	12	to	to	TO
cord-347000-zxytdb0b	183	13	enable	enable	VB
cord-347000-zxytdb0b	183	14	them	-PRON-	PRP
cord-347000-zxytdb0b	183	15	to	to	TO
cord-347000-zxytdb0b	183	16	persist	persist	VB
cord-347000-zxytdb0b	183	17	in	in	IN
cord-347000-zxytdb0b	183	18	the	the	DT
cord-347000-zxytdb0b	183	19	CF	cf	NN
cord-347000-zxytdb0b	183	20	lung	lung	NN
cord-347000-zxytdb0b	183	21	,	,	,
cord-347000-zxytdb0b	183	22	including	include	VBG
cord-347000-zxytdb0b	183	23	constantly	constantly	RB
cord-347000-zxytdb0b	183	24	adapting	adapt	VBG
cord-347000-zxytdb0b	183	25	to	to	IN
cord-347000-zxytdb0b	183	26	a	a	DT
cord-347000-zxytdb0b	183	27	changing	change	VBG
cord-347000-zxytdb0b	183	28	environment	environment	NN
cord-347000-zxytdb0b	183	29	.	.	.
cord-347000-zxytdb0b	184	1	3	3	LS
cord-347000-zxytdb0b	185	1	Not	not	RB
cord-347000-zxytdb0b	185	2	only	only	RB
cord-347000-zxytdb0b	185	3	are	be	VBP
cord-347000-zxytdb0b	185	4	these	these	DT
cord-347000-zxytdb0b	185	5	bacteria	bacteria	NNS
cord-347000-zxytdb0b	185	6	difficult	difficult	JJ
cord-347000-zxytdb0b	185	7	to	to	TO
cord-347000-zxytdb0b	185	8	eradicate	eradicate	VB
cord-347000-zxytdb0b	185	9	,	,	,
cord-347000-zxytdb0b	185	10	but	but	CC
cord-347000-zxytdb0b	185	11	also	also	RB
cord-347000-zxytdb0b	185	12	the	the	DT
cord-347000-zxytdb0b	185	13	phenotypic	phenotypic	JJ
cord-347000-zxytdb0b	185	14	diversity	diversity	NN
cord-347000-zxytdb0b	185	15	observed	observe	VBN
cord-347000-zxytdb0b	185	16	in	in	IN
cord-347000-zxytdb0b	185	17	the	the	DT
cord-347000-zxytdb0b	185	18	laboratory	laboratory	NN
cord-347000-zxytdb0b	185	19	makes	make	VBZ
cord-347000-zxytdb0b	185	20	the	the	DT
cord-347000-zxytdb0b	185	21	design	design	NN
cord-347000-zxytdb0b	185	22	and	and	CC
cord-347000-zxytdb0b	185	23	validation	validation	NN
cord-347000-zxytdb0b	185	24	of	of	IN
cord-347000-zxytdb0b	185	25	new	new	JJ
cord-347000-zxytdb0b	185	26	tests	test	NNS
cord-347000-zxytdb0b	185	27	of	of	IN
cord-347000-zxytdb0b	185	28	antibiotic	antibiotic	JJ
cord-347000-zxytdb0b	185	29	susceptibility	susceptibility	NN
cord-347000-zxytdb0b	185	30	very	very	RB
cord-347000-zxytdb0b	185	31	difficult	difficult	JJ
cord-347000-zxytdb0b	185	32	.	.	.
cord-347000-zxytdb0b	186	1	Future	future	JJ
cord-347000-zxytdb0b	186	2	research	research	NN
cord-347000-zxytdb0b	186	3	is	be	VBZ
cord-347000-zxytdb0b	186	4	needed	need	VBN
cord-347000-zxytdb0b	186	5	to	to	TO
cord-347000-zxytdb0b	186	6	understand	understand	VB
cord-347000-zxytdb0b	186	7	the	the	DT
cord-347000-zxytdb0b	186	8	mechanisms	mechanism	NNS
cord-347000-zxytdb0b	186	9	of	of	IN
cord-347000-zxytdb0b	186	10	pathogenicity	pathogenicity	NN
cord-347000-zxytdb0b	186	11	and	and	CC
cord-347000-zxytdb0b	186	12	persistence	persistence	NN
cord-347000-zxytdb0b	186	13	,	,	,
cord-347000-zxytdb0b	186	14	treatment	treatment	NN
cord-347000-zxytdb0b	186	15	to	to	TO
cord-347000-zxytdb0b	186	16	prevent	prevent	VB
cord-347000-zxytdb0b	186	17	or	or	CC
cord-347000-zxytdb0b	186	18	clear	clear	JJ
cord-347000-zxytdb0b	186	19	infection	infection	NN
cord-347000-zxytdb0b	186	20	and	and	CC
cord-347000-zxytdb0b	186	21	the	the	DT
cord-347000-zxytdb0b	186	22	development	development	NN
cord-347000-zxytdb0b	186	23	of	of	IN
cord-347000-zxytdb0b	186	24	appropriate	appropriate	JJ
cord-347000-zxytdb0b	186	25	laboratory	laboratory	NN
cord-347000-zxytdb0b	186	26	test	test	NN
cord-347000-zxytdb0b	186	27	of	of	IN
cord-347000-zxytdb0b	186	28	susceptibility	susceptibility	NN
cord-347000-zxytdb0b	186	29	relevant	relevant	JJ
cord-347000-zxytdb0b	186	30	to	to	IN
cord-347000-zxytdb0b	186	31	clinical	clinical	JJ
cord-347000-zxytdb0b	186	32	outcome	outcome	NN
cord-347000-zxytdb0b	186	33	.	.	.
cord-347000-zxytdb0b	187	1	Isolates	isolate	NNS
cord-347000-zxytdb0b	187	2	of	of	IN
cord-347000-zxytdb0b	187	3	the	the	DT
cord-347000-zxytdb0b	187	4	species	species	NN
cord-347000-zxytdb0b	187	5	B.	B.	NNP
cord-347000-zxytdb0b	187	6	cepacia	cepacia	NNP
cord-347000-zxytdb0b	187	7	(	(	-LRB-
cord-347000-zxytdb0b	187	8	previously	previously	RB
cord-347000-zxytdb0b	187	9	Pseudomonas	Pseudomonas	NNP
cord-347000-zxytdb0b	187	10	cepacia	cepacia	NNS
cord-347000-zxytdb0b	187	11	)	)	-RRB-
cord-347000-zxytdb0b	187	12	have	have	VBP
cord-347000-zxytdb0b	187	13	been	be	VBN
cord-347000-zxytdb0b	187	14	shown	show	VBN
cord-347000-zxytdb0b	187	15	to	to	TO
cord-347000-zxytdb0b	187	16	consist	consist	VB
cord-347000-zxytdb0b	187	17	of	of	IN
cord-347000-zxytdb0b	187	18	phenotypically	phenotypically	RB
cord-347000-zxytdb0b	187	19	similar	similar	JJ
cord-347000-zxytdb0b	187	20	but	but	CC
cord-347000-zxytdb0b	187	21	genotypically	genotypically	RB
cord-347000-zxytdb0b	187	22	distinct	distinct	JJ
cord-347000-zxytdb0b	187	23	genomovars	genomovar	NNS
cord-347000-zxytdb0b	187	24	.	.	.
cord-347000-zxytdb0b	188	1	39	39	CD
cord-347000-zxytdb0b	189	1	Subsequently	subsequently	RB
cord-347000-zxytdb0b	189	2	,	,	,
cord-347000-zxytdb0b	189	3	the	the	DT
cord-347000-zxytdb0b	189	4	number	number	NN
cord-347000-zxytdb0b	189	5	of	of	IN
cord-347000-zxytdb0b	189	6	genomovars	genomovars	NNP
cord-347000-zxytdb0b	189	7	has	have	VBZ
cord-347000-zxytdb0b	189	8	increased	increase	VBN
cord-347000-zxytdb0b	189	9	and	and	CC
cord-347000-zxytdb0b	189	10	all	all	DT
cord-347000-zxytdb0b	189	11	have	have	VBP
cord-347000-zxytdb0b	189	12	achieved	achieve	VBN
cord-347000-zxytdb0b	189	13	species	species	NN
cord-347000-zxytdb0b	189	14	status	status	NN
cord-347000-zxytdb0b	189	15	.	.	.
cord-347000-zxytdb0b	190	1	Presently	presently	RB
cord-347000-zxytdb0b	190	2	,	,	,
cord-347000-zxytdb0b	190	3	the	the	DT
cord-347000-zxytdb0b	190	4	so	so	RB
cord-347000-zxytdb0b	190	5	-	-	HYPH
cord-347000-zxytdb0b	190	6	called	call	VBN
cord-347000-zxytdb0b	190	7	Bcc	Bcc	NNP
cord-347000-zxytdb0b	190	8	comprises	comprise	VBZ
cord-347000-zxytdb0b	190	9	at	at	RB
cord-347000-zxytdb0b	190	10	least	least	RBS
cord-347000-zxytdb0b	190	11	15	15	CD
cord-347000-zxytdb0b	190	12	species	specie	NNS
cord-347000-zxytdb0b	190	13	.	.	.
cord-347000-zxytdb0b	191	1	40	40	CD
cord-347000-zxytdb0b	192	1	They	-PRON-	PRP
cord-347000-zxytdb0b	192	2	are	be	VBP
cord-347000-zxytdb0b	192	3	natural	natural	JJ
cord-347000-zxytdb0b	192	4	soil	soil	NN
cord-347000-zxytdb0b	192	5	bacteria	bacteria	NNS
cord-347000-zxytdb0b	192	6	,	,	,
cord-347000-zxytdb0b	192	7	found	find	VBN
cord-347000-zxytdb0b	192	8	in	in	IN
cord-347000-zxytdb0b	192	9	the	the	DT
cord-347000-zxytdb0b	192	10	rhizosphere	rhizosphere	NN
cord-347000-zxytdb0b	192	11	and	and	CC
cord-347000-zxytdb0b	192	12	can	can	MD
cord-347000-zxytdb0b	192	13	be	be	VB
cord-347000-zxytdb0b	192	14	plant	plant	NN
cord-347000-zxytdb0b	192	15	symbionts	symbiont	NNS
cord-347000-zxytdb0b	192	16	or	or	CC
cord-347000-zxytdb0b	192	17	pathogens	pathogen	NNS
cord-347000-zxytdb0b	192	18	.	.	.
cord-347000-zxytdb0b	193	1	While	while	IN
cord-347000-zxytdb0b	193	2	they	-PRON-	PRP
cord-347000-zxytdb0b	193	3	can	can	MD
cord-347000-zxytdb0b	193	4	be	be	VB
cord-347000-zxytdb0b	193	5	opportunist	opportunist	JJ
cord-347000-zxytdb0b	193	6	pathogens	pathogen	NNS
cord-347000-zxytdb0b	193	7	affecting	affect	VBG
cord-347000-zxytdb0b	193	8	patients	patient	NNS
cord-347000-zxytdb0b	193	9	who	who	WP
cord-347000-zxytdb0b	193	10	are	be	VBP
cord-347000-zxytdb0b	193	11	severely	severely	RB
cord-347000-zxytdb0b	193	12	immuno	immuno	JJ
cord-347000-zxytdb0b	193	13	-	-	HYPH
cord-347000-zxytdb0b	193	14	suppressed	suppress	VBN
cord-347000-zxytdb0b	193	15	or	or	CC
cord-347000-zxytdb0b	193	16	following	follow	VBG
cord-347000-zxytdb0b	193	17	contamination	contamination	NN
cord-347000-zxytdb0b	193	18	of	of	IN
cord-347000-zxytdb0b	193	19	fluids	fluid	NNS
cord-347000-zxytdb0b	193	20	or	or	CC
cord-347000-zxytdb0b	193	21	medical	medical	JJ
cord-347000-zxytdb0b	193	22	devices	device	NNS
cord-347000-zxytdb0b	193	23	,	,	,
cord-347000-zxytdb0b	193	24	they	-PRON-	PRP
cord-347000-zxytdb0b	193	25	only	only	RB
cord-347000-zxytdb0b	193	26	cause	cause	VBP
cord-347000-zxytdb0b	193	27	significant	significant	JJ
cord-347000-zxytdb0b	193	28	primary	primary	JJ
cord-347000-zxytdb0b	193	29	infection	infection	NN
cord-347000-zxytdb0b	193	30	in	in	IN
cord-347000-zxytdb0b	193	31	patients	patient	NNS
cord-347000-zxytdb0b	193	32	with	with	IN
cord-347000-zxytdb0b	193	33	CF	cf	NN
cord-347000-zxytdb0b	193	34	or	or	CC
cord-347000-zxytdb0b	193	35	chronic	chronic	JJ
cord-347000-zxytdb0b	193	36	granulomatous	granulomatous	JJ
cord-347000-zxytdb0b	193	37	disease	disease	NN
cord-347000-zxytdb0b	193	38	(	(	-LRB-
cord-347000-zxytdb0b	193	39	CGD	CGD	NNP
cord-347000-zxytdb0b	193	40	)	)	-RRB-
cord-347000-zxytdb0b	193	41	.	.	.
cord-347000-zxytdb0b	194	1	While	while	IN
cord-347000-zxytdb0b	194	2	patients	patient	NNS
cord-347000-zxytdb0b	194	3	with	with	IN
cord-347000-zxytdb0b	194	4	CGD	CGD	NNP
cord-347000-zxytdb0b	194	5	have	have	VBP
cord-347000-zxytdb0b	194	6	a	a	DT
cord-347000-zxytdb0b	194	7	specific	specific	JJ
cord-347000-zxytdb0b	194	8	immune	immune	JJ
cord-347000-zxytdb0b	194	9	defect	defect	NN
cord-347000-zxytdb0b	194	10	in	in	IN
cord-347000-zxytdb0b	194	11	the	the	DT
cord-347000-zxytdb0b	194	12	oxidative	oxidative	JJ
cord-347000-zxytdb0b	194	13	burst	burst	NN
cord-347000-zxytdb0b	194	14	pathway	pathway	NN
cord-347000-zxytdb0b	194	15	,	,	,
cord-347000-zxytdb0b	194	16	the	the	DT
cord-347000-zxytdb0b	194	17	reason	reason	NN
cord-347000-zxytdb0b	194	18	for	for	IN
cord-347000-zxytdb0b	194	19	the	the	DT
cord-347000-zxytdb0b	194	20	association	association	NN
cord-347000-zxytdb0b	194	21	with	with	IN
cord-347000-zxytdb0b	194	22	CF	CF	NNP
cord-347000-zxytdb0b	194	23	is	be	VBZ
cord-347000-zxytdb0b	194	24	still	still	RB
cord-347000-zxytdb0b	194	25	unknown	unknown	JJ
cord-347000-zxytdb0b	194	26	.	.	.
cord-347000-zxytdb0b	195	1	Patients	patient	NNS
cord-347000-zxytdb0b	195	2	with	with	IN
cord-347000-zxytdb0b	195	3	non	non	JJ
cord-347000-zxytdb0b	195	4	-	-	JJ
cord-347000-zxytdb0b	195	5	CF	cf	JJ
cord-347000-zxytdb0b	195	6	bronchiectasis	bronchiectasis	NN
cord-347000-zxytdb0b	195	7	do	do	VBP
cord-347000-zxytdb0b	195	8	not	not	RB
cord-347000-zxytdb0b	195	9	get	get	VB
cord-347000-zxytdb0b	195	10	infected	infect	VBN
cord-347000-zxytdb0b	195	11	with	with	IN
cord-347000-zxytdb0b	195	12	Bcc	Bcc	NNP
cord-347000-zxytdb0b	195	13	.	.	.
cord-347000-zxytdb0b	196	1	These	these	DT
cord-347000-zxytdb0b	196	2	are	be	VBP
cord-347000-zxytdb0b	196	3	complex	complex	JJ
cord-347000-zxytdb0b	196	4	organisms	organism	NNS
cord-347000-zxytdb0b	196	5	with	with	IN
cord-347000-zxytdb0b	196	6	a	a	DT
cord-347000-zxytdb0b	196	7	range	range	NN
cord-347000-zxytdb0b	196	8	of	of	IN
cord-347000-zxytdb0b	196	9	pathogenicity	pathogenicity	NN
cord-347000-zxytdb0b	196	10	factors	factor	NNS
cord-347000-zxytdb0b	196	11	,	,	,
cord-347000-zxytdb0b	196	12	many	many	JJ
cord-347000-zxytdb0b	196	13	regulated	regulate	VBN
cord-347000-zxytdb0b	196	14	by	by	IN
cord-347000-zxytdb0b	196	15	QS	QS	NNP
cord-347000-zxytdb0b	196	16	systems	system	NNS
cord-347000-zxytdb0b	196	17	,	,	,
cord-347000-zxytdb0b	196	18	similar	similar	JJ
cord-347000-zxytdb0b	196	19	to	to	IN
cord-347000-zxytdb0b	196	20	P.	P.	NNP
cord-347000-zxytdb0b	196	21	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	196	22	.	.	.
cord-347000-zxytdb0b	197	1	41	41	CD
cord-347000-zxytdb0b	198	1	Burkholderia	Burkholderia	NNP
cord-347000-zxytdb0b	198	2	spp	spp	NNP
cord-347000-zxytdb0b	198	3	.	.	.
cord-347000-zxytdb0b	199	1	are	be	VBP
cord-347000-zxytdb0b	199	2	resistant	resistant	JJ
cord-347000-zxytdb0b	199	3	to	to	IN
cord-347000-zxytdb0b	199	4	colistin	colistin	NNP
cord-347000-zxytdb0b	199	5	and	and	CC
cord-347000-zxytdb0b	199	6	often	often	RB
cord-347000-zxytdb0b	199	7	multi	multi	JJ
cord-347000-zxytdb0b	199	8	-	-	:
cord-347000-zxytdb0b	199	9	or	or	CC
cord-347000-zxytdb0b	199	10	even	even	RB
cord-347000-zxytdb0b	199	11	panresistant	panresistant	JJ
cord-347000-zxytdb0b	199	12	.	.	.
cord-347000-zxytdb0b	200	1	Some	some	DT
cord-347000-zxytdb0b	200	2	combinations	combination	NNS
cord-347000-zxytdb0b	200	3	of	of	IN
cord-347000-zxytdb0b	200	4	antibiotics	antibiotic	NNS
cord-347000-zxytdb0b	200	5	are	be	VBP
cord-347000-zxytdb0b	200	6	effective	effective	JJ
cord-347000-zxytdb0b	200	7	in	in	IN
cord-347000-zxytdb0b	200	8	vitro	vitro	FW
cord-347000-zxytdb0b	200	9	but	but	CC
cord-347000-zxytdb0b	200	10	there	there	EX
cord-347000-zxytdb0b	200	11	is	be	VBZ
cord-347000-zxytdb0b	200	12	little	little	JJ
cord-347000-zxytdb0b	200	13	evidence	evidence	NN
cord-347000-zxytdb0b	200	14	to	to	TO
cord-347000-zxytdb0b	200	15	correlate	correlate	VB
cord-347000-zxytdb0b	200	16	the	the	DT
cord-347000-zxytdb0b	200	17	results	result	NNS
cord-347000-zxytdb0b	200	18	with	with	IN
cord-347000-zxytdb0b	200	19	the	the	DT
cord-347000-zxytdb0b	200	20	clinical	clinical	JJ
cord-347000-zxytdb0b	200	21	response	response	NN
cord-347000-zxytdb0b	200	22	to	to	IN
cord-347000-zxytdb0b	200	23	treatment	treatment	NN
cord-347000-zxytdb0b	200	24	.	.	.
cord-347000-zxytdb0b	201	1	31	31	CD
cord-347000-zxytdb0b	202	1	The	the	DT
cord-347000-zxytdb0b	202	2	importance	importance	NN
cord-347000-zxytdb0b	202	3	of	of	IN
cord-347000-zxytdb0b	202	4	Bcc	Bcc	NNP
cord-347000-zxytdb0b	202	5	in	in	IN
cord-347000-zxytdb0b	202	6	CF	CF	NNP
cord-347000-zxytdb0b	202	7	was	be	VBD
cord-347000-zxytdb0b	202	8	first	first	RB
cord-347000-zxytdb0b	202	9	recognized	recognize	VBN
cord-347000-zxytdb0b	202	10	following	follow	VBG
cord-347000-zxytdb0b	202	11	outbreaks	outbreak	NNS
cord-347000-zxytdb0b	202	12	in	in	IN
cord-347000-zxytdb0b	202	13	the	the	DT
cord-347000-zxytdb0b	202	14	1980s	1980s	CD
cord-347000-zxytdb0b	202	15	.	.	.
cord-347000-zxytdb0b	203	1	42	42	CD
cord-347000-zxytdb0b	204	1	By	by	IN
cord-347000-zxytdb0b	204	2	the	the	DT
cord-347000-zxytdb0b	204	3	1990s	1990	NNS
cord-347000-zxytdb0b	204	4	,	,	,
cord-347000-zxytdb0b	204	5	the	the	DT
cord-347000-zxytdb0b	204	6	ET12	ET12	NNP
cord-347000-zxytdb0b	204	7	strain	strain	NN
cord-347000-zxytdb0b	204	8	of	of	IN
cord-347000-zxytdb0b	204	9	Burkholderia	Burkholderia	NNP
cord-347000-zxytdb0b	204	10	cenocepacia	cenocepacia	NNP
cord-347000-zxytdb0b	204	11	was	be	VBD
cord-347000-zxytdb0b	204	12	the	the	DT
cord-347000-zxytdb0b	204	13	most	most	RBS
cord-347000-zxytdb0b	204	14	common	common	JJ
cord-347000-zxytdb0b	204	15	in	in	IN
cord-347000-zxytdb0b	204	16	the	the	DT
cord-347000-zxytdb0b	204	17	UK	UK	NNP
cord-347000-zxytdb0b	204	18	and	and	CC
cord-347000-zxytdb0b	204	19	Canada	Canada	NNP
cord-347000-zxytdb0b	204	20	.	.	.
cord-347000-zxytdb0b	205	1	This	this	DT
cord-347000-zxytdb0b	205	2	was	be	VBD
cord-347000-zxytdb0b	205	3	highly	highly	RB
cord-347000-zxytdb0b	205	4	transmissible	transmissible	JJ
cord-347000-zxytdb0b	205	5	and	and	CC
cord-347000-zxytdb0b	205	6	pathogenic	pathogenic	JJ
cord-347000-zxytdb0b	205	7	and	and	CC
cord-347000-zxytdb0b	205	8	led	lead	VBD
cord-347000-zxytdb0b	205	9	to	to	IN
cord-347000-zxytdb0b	205	10	many	many	JJ
cord-347000-zxytdb0b	205	11	deaths	death	NNS
cord-347000-zxytdb0b	205	12	due	due	JJ
cord-347000-zxytdb0b	205	13	to	to	IN
cord-347000-zxytdb0b	205	14	a	a	DT
cord-347000-zxytdb0b	205	15	rapidly	rapidly	RB
cord-347000-zxytdb0b	205	16	progressing	progress	VBG
cord-347000-zxytdb0b	205	17	pneumonia	pneumonia	NN
cord-347000-zxytdb0b	205	18	sometimes	sometimes	RB
cord-347000-zxytdb0b	205	19	with	with	IN
cord-347000-zxytdb0b	205	20	bacteraemia	bacteraemia	NNP
cord-347000-zxytdb0b	205	21	,	,	,
cord-347000-zxytdb0b	205	22	referred	refer	VBD
cord-347000-zxytdb0b	205	23	to	to	IN
cord-347000-zxytdb0b	205	24	as	as	IN
cord-347000-zxytdb0b	205	25	the	the	DT
cord-347000-zxytdb0b	205	26	'	'	``
cord-347000-zxytdb0b	205	27	cepacia	cepacia	NNP
cord-347000-zxytdb0b	205	28	syndrome	syndrome	NNP
cord-347000-zxytdb0b	205	29	'	'	''
cord-347000-zxytdb0b	205	30	.	.	.
cord-347000-zxytdb0b	206	1	Bcc	Bcc	NNP
cord-347000-zxytdb0b	206	2	survives	survive	VBZ
cord-347000-zxytdb0b	206	3	well	well	RB
cord-347000-zxytdb0b	206	4	in	in	IN
cord-347000-zxytdb0b	206	5	natural	natural	JJ
cord-347000-zxytdb0b	206	6	and	and	CC
cord-347000-zxytdb0b	206	7	healthcare	healthcare	NN
cord-347000-zxytdb0b	206	8	environments	environment	NNS
cord-347000-zxytdb0b	206	9	and	and	CC
cord-347000-zxytdb0b	206	10	some	some	DT
cord-347000-zxytdb0b	206	11	strains	strain	NNS
cord-347000-zxytdb0b	206	12	most	most	RBS
cord-347000-zxytdb0b	206	13	notably	notably	RB
cord-347000-zxytdb0b	206	14	the	the	DT
cord-347000-zxytdb0b	206	15	ET12	ET12	NNP
cord-347000-zxytdb0b	206	16	lineage	lineage	NN
cord-347000-zxytdb0b	206	17	of	of	IN
cord-347000-zxytdb0b	206	18	B.	B.	NNP
cord-347000-zxytdb0b	206	19	cenocepacia	cenocepacia	NNP
cord-347000-zxytdb0b	206	20	easily	easily	RB
cord-347000-zxytdb0b	206	21	spread	spread	VBN
cord-347000-zxytdb0b	206	22	between	between	IN
cord-347000-zxytdb0b	206	23	patients	patient	NNS
cord-347000-zxytdb0b	206	24	.	.	.
cord-347000-zxytdb0b	207	1	Controls	control	NNS
cord-347000-zxytdb0b	207	2	to	to	TO
cord-347000-zxytdb0b	207	3	reduce	reduce	VB
cord-347000-zxytdb0b	207	4	cross	cross	NN
cord-347000-zxytdb0b	207	5	-	-	NN
cord-347000-zxytdb0b	207	6	infection	infection	NN
cord-347000-zxytdb0b	207	7	including	include	VBG
cord-347000-zxytdb0b	207	8	segregating	segregate	VBG
cord-347000-zxytdb0b	207	9	patients	patient	NNS
cord-347000-zxytdb0b	207	10	have	have	VBP
cord-347000-zxytdb0b	207	11	been	be	VBN
cord-347000-zxytdb0b	207	12	the	the	DT
cord-347000-zxytdb0b	207	13	main	main	JJ
cord-347000-zxytdb0b	207	14	reason	reason	NN
cord-347000-zxytdb0b	207	15	that	that	IN
cord-347000-zxytdb0b	207	16	infection	infection	NN
cord-347000-zxytdb0b	207	17	and	and	CC
cord-347000-zxytdb0b	207	18	mortality	mortality	NN
cord-347000-zxytdb0b	207	19	has	have	VBZ
cord-347000-zxytdb0b	207	20	declined	decline	VBN
cord-347000-zxytdb0b	207	21	significantly	significantly	RB
cord-347000-zxytdb0b	207	22	.	.	.
cord-347000-zxytdb0b	208	1	In	in	IN
cord-347000-zxytdb0b	208	2	the	the	DT
cord-347000-zxytdb0b	208	3	UK	UK	NNP
cord-347000-zxytdb0b	208	4	,	,	,
cord-347000-zxytdb0b	208	5	the	the	DT
cord-347000-zxytdb0b	208	6	most	most	RBS
cord-347000-zxytdb0b	208	7	common	common	JJ
cord-347000-zxytdb0b	208	8	species	specie	NNS
cord-347000-zxytdb0b	208	9	seen	see	VBN
cord-347000-zxytdb0b	208	10	is	be	VBZ
cord-347000-zxytdb0b	209	1	Burkholderia	Burkholderia	NNP
cord-347000-zxytdb0b	209	2	multivorans	multivorans	NNPS
cord-347000-zxytdb0b	209	3	and	and	CC
cord-347000-zxytdb0b	209	4	most	most	JJS
cord-347000-zxytdb0b	209	5	new	new	JJ
cord-347000-zxytdb0b	209	6	infections	infection	NNS
cord-347000-zxytdb0b	209	7	are	be	VBP
cord-347000-zxytdb0b	209	8	caused	cause	VBN
cord-347000-zxytdb0b	209	9	by	by	IN
cord-347000-zxytdb0b	209	10	unrelated	unrelated	JJ
cord-347000-zxytdb0b	209	11	clones	clone	NNS
cord-347000-zxytdb0b	209	12	,	,	,
cord-347000-zxytdb0b	209	13	suggesting	suggest	VBG
cord-347000-zxytdb0b	209	14	an	an	DT
cord-347000-zxytdb0b	209	15	environmental	environmental	JJ
cord-347000-zxytdb0b	209	16	source	source	NN
cord-347000-zxytdb0b	209	17	rather	rather	RB
cord-347000-zxytdb0b	209	18	than	than	IN
cord-347000-zxytdb0b	209	19	person	person	NN
cord-347000-zxytdb0b	209	20	-	-	HYPH
cord-347000-zxytdb0b	209	21	to	to	IN
cord-347000-zxytdb0b	209	22	-	-	HYPH
cord-347000-zxytdb0b	209	23	person	person	NN
cord-347000-zxytdb0b	209	24	spread	spread	NN
cord-347000-zxytdb0b	209	25	.	.	.
cord-347000-zxytdb0b	210	1	Infection	infection	NN
cord-347000-zxytdb0b	210	2	with	with	IN
cord-347000-zxytdb0b	210	3	Bcc	Bcc	NNP
cord-347000-zxytdb0b	210	4	is	be	VBZ
cord-347000-zxytdb0b	210	5	more	more	RBR
cord-347000-zxytdb0b	210	6	common	common	JJ
cord-347000-zxytdb0b	210	7	in	in	IN
cord-347000-zxytdb0b	210	8	older	old	JJR
cord-347000-zxytdb0b	210	9	CF	cf	NN
cord-347000-zxytdb0b	210	10	patients	patient	NNS
cord-347000-zxytdb0b	210	11	but	but	CC
cord-347000-zxytdb0b	210	12	can	can	MD
cord-347000-zxytdb0b	210	13	occur	occur	VB
cord-347000-zxytdb0b	210	14	at	at	IN
cord-347000-zxytdb0b	210	15	any	any	DT
cord-347000-zxytdb0b	210	16	time	time	NN
cord-347000-zxytdb0b	210	17	in	in	IN
cord-347000-zxytdb0b	210	18	the	the	DT
cord-347000-zxytdb0b	210	19	patient	patient	NN
cord-347000-zxytdb0b	210	20	's	's	POS
cord-347000-zxytdb0b	210	21	life	life	NN
cord-347000-zxytdb0b	210	22	.	.	.
cord-347000-zxytdb0b	211	1	Cepacia	Cepacia	NNP
cord-347000-zxytdb0b	211	2	syndrome	syndrome	NN
cord-347000-zxytdb0b	211	3	can	can	MD
cord-347000-zxytdb0b	211	4	occur	occur	VB
cord-347000-zxytdb0b	211	5	when	when	WRB
cord-347000-zxytdb0b	211	6	the	the	DT
cord-347000-zxytdb0b	211	7	organism	organism	NN
cord-347000-zxytdb0b	211	8	is	be	VBZ
cord-347000-zxytdb0b	211	9	first	first	RB
cord-347000-zxytdb0b	211	10	acquired	acquire	VBN
cord-347000-zxytdb0b	211	11	or	or	CC
cord-347000-zxytdb0b	211	12	unexpectedly	unexpectedly	RB
cord-347000-zxytdb0b	211	13	many	many	JJ
cord-347000-zxytdb0b	211	14	years	year	NNS
cord-347000-zxytdb0b	211	15	after	after	IN
cord-347000-zxytdb0b	211	16	initial	initial	JJ
cord-347000-zxytdb0b	211	17	infection	infection	NN
cord-347000-zxytdb0b	211	18	.	.	.
cord-347000-zxytdb0b	212	1	It	-PRON-	PRP
cord-347000-zxytdb0b	212	2	is	be	VBZ
cord-347000-zxytdb0b	212	3	most	most	RBS
cord-347000-zxytdb0b	212	4	frequently	frequently	RB
cord-347000-zxytdb0b	212	5	due	due	JJ
cord-347000-zxytdb0b	212	6	to	to	IN
cord-347000-zxytdb0b	212	7	B.	B.	NNP
cord-347000-zxytdb0b	212	8	cenocepacia	cenocepacia	NNP
cord-347000-zxytdb0b	212	9	;	;	:
cord-347000-zxytdb0b	212	10	however	however	RB
cord-347000-zxytdb0b	212	11	,	,	,
cord-347000-zxytdb0b	212	12	both	both	CC
cord-347000-zxytdb0b	212	13	B.	B.	NNP
cord-347000-zxytdb0b	212	14	multivorans	multivorans	NNPS
cord-347000-zxytdb0b	212	15	and	and	CC
cord-347000-zxytdb0b	212	16	Burkholderia	Burkholderia	NNP
cord-347000-zxytdb0b	212	17	dolosa	dolosa	NNP
cord-347000-zxytdb0b	212	18	can	can	MD
cord-347000-zxytdb0b	212	19	also	also	RB
cord-347000-zxytdb0b	212	20	cause	cause	VB
cord-347000-zxytdb0b	212	21	the	the	DT
cord-347000-zxytdb0b	212	22	'	'	``
cord-347000-zxytdb0b	212	23	cepacia	cepacia	NNP
cord-347000-zxytdb0b	212	24	syndrome	syndrome	NNP
cord-347000-zxytdb0b	212	25	'	'	''
cord-347000-zxytdb0b	212	26	.	.	.
cord-347000-zxytdb0b	213	1	43	43	CD
cord-347000-zxytdb0b	214	1	Of	of	IN
cord-347000-zxytdb0b	214	2	the	the	DT
cord-347000-zxytdb0b	214	3	potential	potential	JJ
cord-347000-zxytdb0b	214	4	pathogenicity	pathogenicity	NN
cord-347000-zxytdb0b	214	5	factors	factor	NNS
cord-347000-zxytdb0b	214	6	(	(	-LRB-
cord-347000-zxytdb0b	214	7	LPS	LPS	NNP
cord-347000-zxytdb0b	214	8	,	,	,
cord-347000-zxytdb0b	214	9	specific	specific	JJ
cord-347000-zxytdb0b	214	10	cytotoxins	cytotoxin	NNS
cord-347000-zxytdb0b	214	11	and	and	CC
cord-347000-zxytdb0b	214	12	the	the	DT
cord-347000-zxytdb0b	214	13	ability	ability	NN
cord-347000-zxytdb0b	214	14	to	to	TO
cord-347000-zxytdb0b	214	15	form	form	VB
cord-347000-zxytdb0b	214	16	biofilms	biofilm	NNS
cord-347000-zxytdb0b	214	17	)	)	-RRB-
cord-347000-zxytdb0b	215	1	many	many	JJ
cord-347000-zxytdb0b	215	2	are	be	VBP
cord-347000-zxytdb0b	215	3	controlled	control	VBN
cord-347000-zxytdb0b	215	4	by	by	IN
cord-347000-zxytdb0b	215	5	QS	QS	NNP
cord-347000-zxytdb0b	215	6	.	.	.
cord-347000-zxytdb0b	216	1	In	in	IN
cord-347000-zxytdb0b	216	2	addition	addition	NN
cord-347000-zxytdb0b	216	3	,	,	,
cord-347000-zxytdb0b	216	4	Bcc	Bcc	NNP
cord-347000-zxytdb0b	216	5	are	be	VBP
cord-347000-zxytdb0b	216	6	able	able	JJ
cord-347000-zxytdb0b	216	7	to	to	TO
cord-347000-zxytdb0b	216	8	survive	survive	VB
cord-347000-zxytdb0b	216	9	in	in	IN
cord-347000-zxytdb0b	216	10	cultured	cultured	JJ
cord-347000-zxytdb0b	216	11	human	human	JJ
cord-347000-zxytdb0b	216	12	epithelial	epithelial	JJ
cord-347000-zxytdb0b	216	13	cells	cell	NNS
cord-347000-zxytdb0b	216	14	and	and	CC
cord-347000-zxytdb0b	216	15	macrophages	macrophage	NNS
cord-347000-zxytdb0b	216	16	.	.	.
cord-347000-zxytdb0b	217	1	Severity	severity	NN
cord-347000-zxytdb0b	217	2	of	of	IN
cord-347000-zxytdb0b	217	3	disease	disease	NN
cord-347000-zxytdb0b	217	4	may	may	MD
cord-347000-zxytdb0b	217	5	be	be	VB
cord-347000-zxytdb0b	217	6	strain	strain	NN
cord-347000-zxytdb0b	217	7	rather	rather	RB
cord-347000-zxytdb0b	217	8	than	than	IN
cord-347000-zxytdb0b	217	9	species	species	NN
cord-347000-zxytdb0b	217	10	-	-	HYPH
cord-347000-zxytdb0b	217	11	specific	specific	JJ
cord-347000-zxytdb0b	217	12	;	;	:
cord-347000-zxytdb0b	217	13	however	however	RB
cord-347000-zxytdb0b	217	14	,	,	,
cord-347000-zxytdb0b	217	15	it	-PRON-	PRP
cord-347000-zxytdb0b	217	16	may	may	MD
cord-347000-zxytdb0b	217	17	also	also	RB
cord-347000-zxytdb0b	217	18	be	be	VB
cord-347000-zxytdb0b	217	19	dependent	dependent	JJ
cord-347000-zxytdb0b	217	20	on	on	IN
cord-347000-zxytdb0b	217	21	patient	patient	JJ
cord-347000-zxytdb0b	217	22	factors	factor	NNS
cord-347000-zxytdb0b	217	23	and	and	CC
cord-347000-zxytdb0b	217	24	interactions	interaction	NNS
cord-347000-zxytdb0b	217	25	with	with	IN
cord-347000-zxytdb0b	217	26	other	other	JJ
cord-347000-zxytdb0b	217	27	pathogens	pathogen	NNS
cord-347000-zxytdb0b	217	28	.	.	.
cord-347000-zxytdb0b	218	1	Of	of	IN
cord-347000-zxytdb0b	218	2	note	note	NN
cord-347000-zxytdb0b	218	3	,	,	,
cord-347000-zxytdb0b	218	4	neither	neither	CC
cord-347000-zxytdb0b	218	5	the	the	DT
cord-347000-zxytdb0b	218	6	presence	presence	NN
cord-347000-zxytdb0b	218	7	of	of	IN
cord-347000-zxytdb0b	218	8	cable	cable	NN
cord-347000-zxytdb0b	218	9	pili	pili	NNP
cord-347000-zxytdb0b	218	10	nor	nor	CC
cord-347000-zxytdb0b	218	11	the	the	DT
cord-347000-zxytdb0b	218	12	presence	presence	NN
cord-347000-zxytdb0b	218	13	of	of	IN
cord-347000-zxytdb0b	218	14	B.	B.	NNP
cord-347000-zxytdb0b	218	15	cepacia	cepacia	NNP
cord-347000-zxytdb0b	218	16	epidemic	epidemic	NN
cord-347000-zxytdb0b	218	17	strain	strain	NN
cord-347000-zxytdb0b	218	18	marker	marker	NN
cord-347000-zxytdb0b	218	19	is	be	VBZ
cord-347000-zxytdb0b	218	20	now	now	RB
cord-347000-zxytdb0b	218	21	considered	consider	VBN
cord-347000-zxytdb0b	218	22	as	as	IN
cord-347000-zxytdb0b	218	23	a	a	DT
cord-347000-zxytdb0b	218	24	reliable	reliable	JJ
cord-347000-zxytdb0b	218	25	indicator	indicator	NN
cord-347000-zxytdb0b	218	26	of	of	IN
cord-347000-zxytdb0b	218	27	virulence	virulence	NN
cord-347000-zxytdb0b	218	28	or	or	CC
cord-347000-zxytdb0b	218	29	transmissibility	transmissibility	NN
cord-347000-zxytdb0b	218	30	.	.	.
cord-347000-zxytdb0b	219	1	42	42	CD
cord-347000-zxytdb0b	219	2	Chronic	chronic	JJ
cord-347000-zxytdb0b	219	3	infection	infection	NN
cord-347000-zxytdb0b	219	4	may	may	MD
cord-347000-zxytdb0b	219	5	develop	develop	VB
cord-347000-zxytdb0b	219	6	with	with	IN
cord-347000-zxytdb0b	219	7	acute	acute	JJ
cord-347000-zxytdb0b	219	8	exacerbations	exacerbation	NNS
cord-347000-zxytdb0b	219	9	and	and	CC
cord-347000-zxytdb0b	219	10	a	a	DT
cord-347000-zxytdb0b	219	11	gradual	gradual	JJ
cord-347000-zxytdb0b	219	12	decline	decline	NN
cord-347000-zxytdb0b	219	13	in	in	IN
cord-347000-zxytdb0b	219	14	lung	lung	NN
cord-347000-zxytdb0b	219	15	function	function	NN
cord-347000-zxytdb0b	219	16	.	.	.
cord-347000-zxytdb0b	220	1	While	while	IN
cord-347000-zxytdb0b	220	2	transmissible	transmissible	JJ
cord-347000-zxytdb0b	220	3	species	specie	NNS
cord-347000-zxytdb0b	220	4	can	can	MD
cord-347000-zxytdb0b	220	5	replace	replace	VB
cord-347000-zxytdb0b	220	6	other	other	JJ
cord-347000-zxytdb0b	220	7	Burkholderia	Burkholderia	NNP
cord-347000-zxytdb0b	220	8	spp	spp	NNS
cord-347000-zxytdb0b	220	9	.	.	.
cord-347000-zxytdb0b	221	1	causing	cause	VBG
cord-347000-zxytdb0b	221	2	chronic	chronic	JJ
cord-347000-zxytdb0b	221	3	infection	infection	NN
cord-347000-zxytdb0b	221	4	,	,	,
cord-347000-zxytdb0b	221	5	exacerbations	exacerbation	NNS
cord-347000-zxytdb0b	221	6	are	be	VBP
cord-347000-zxytdb0b	221	7	not	not	RB
cord-347000-zxytdb0b	221	8	associated	associate	VBN
cord-347000-zxytdb0b	221	9	with	with	IN
cord-347000-zxytdb0b	221	10	acquisition	acquisition	NN
cord-347000-zxytdb0b	221	11	of	of	IN
cord-347000-zxytdb0b	221	12	a	a	DT
cord-347000-zxytdb0b	221	13	new	new	JJ
cord-347000-zxytdb0b	221	14	species	specie	NNS
cord-347000-zxytdb0b	221	15	or	or	CC
cord-347000-zxytdb0b	221	16	strain	strain	NN
cord-347000-zxytdb0b	221	17	.	.	.
cord-347000-zxytdb0b	222	1	44	44	CD
cord-347000-zxytdb0b	222	2	Factors	factor	NNS
cord-347000-zxytdb0b	222	3	that	that	WDT
cord-347000-zxytdb0b	222	4	lead	lead	VBP
cord-347000-zxytdb0b	222	5	to	to	IN
cord-347000-zxytdb0b	222	6	more	more	RBR
cord-347000-zxytdb0b	222	7	severe	severe	JJ
cord-347000-zxytdb0b	222	8	disease	disease	NN
cord-347000-zxytdb0b	222	9	with	with	IN
cord-347000-zxytdb0b	222	10	certain	certain	JJ
cord-347000-zxytdb0b	222	11	species	specie	NNS
cord-347000-zxytdb0b	222	12	or	or	CC
cord-347000-zxytdb0b	222	13	strains	strain	NNS
cord-347000-zxytdb0b	222	14	are	be	VBP
cord-347000-zxytdb0b	222	15	still	still	RB
cord-347000-zxytdb0b	222	16	unclear	unclear	JJ
cord-347000-zxytdb0b	222	17	.	.	.
cord-347000-zxytdb0b	223	1	The	the	DT
cord-347000-zxytdb0b	223	2	relevance	relevance	NN
cord-347000-zxytdb0b	223	3	of	of	IN
cord-347000-zxytdb0b	223	4	other	other	JJ
cord-347000-zxytdb0b	223	5	members	member	NNS
cord-347000-zxytdb0b	223	6	of	of	IN
cord-347000-zxytdb0b	223	7	the	the	DT
cord-347000-zxytdb0b	223	8	complex	complex	NN
cord-347000-zxytdb0b	223	9	is	be	VBZ
cord-347000-zxytdb0b	223	10	unclear	unclear	JJ
cord-347000-zxytdb0b	223	11	.	.	.
cord-347000-zxytdb0b	224	1	Prompt	prompt	JJ
cord-347000-zxytdb0b	224	2	and	and	CC
cord-347000-zxytdb0b	224	3	accurate	accurate	JJ
cord-347000-zxytdb0b	224	4	laboratory	laboratory	NN
cord-347000-zxytdb0b	224	5	identification	identification	NN
cord-347000-zxytdb0b	224	6	of	of	IN
cord-347000-zxytdb0b	224	7	Bcc	Bcc	NNP
cord-347000-zxytdb0b	224	8	is	be	VBZ
cord-347000-zxytdb0b	224	9	very	very	RB
cord-347000-zxytdb0b	224	10	important	important	JJ
cord-347000-zxytdb0b	224	11	because	because	IN
cord-347000-zxytdb0b	224	12	of	of	IN
cord-347000-zxytdb0b	224	13	the	the	DT
cord-347000-zxytdb0b	224	14	implications	implication	NNS
cord-347000-zxytdb0b	224	15	for	for	IN
cord-347000-zxytdb0b	224	16	the	the	DT
cord-347000-zxytdb0b	224	17	patient	patient	NN
cord-347000-zxytdb0b	224	18	's	's	POS
cord-347000-zxytdb0b	224	19	care	care	NN
cord-347000-zxytdb0b	224	20	and	and	CC
cord-347000-zxytdb0b	224	21	the	the	DT
cord-347000-zxytdb0b	224	22	need	need	NN
cord-347000-zxytdb0b	224	23	to	to	TO
cord-347000-zxytdb0b	224	24	prevent	prevent	VB
cord-347000-zxytdb0b	224	25	cross	cross	NN
cord-347000-zxytdb0b	224	26	-	-	NN
cord-347000-zxytdb0b	224	27	infection	infection	NN
cord-347000-zxytdb0b	224	28	.	.	.
cord-347000-zxytdb0b	225	1	Commercial	commercial	JJ
cord-347000-zxytdb0b	225	2	identification	identification	NN
cord-347000-zxytdb0b	225	3	systems	system	NNS
cord-347000-zxytdb0b	225	4	are	be	VBP
cord-347000-zxytdb0b	225	5	not	not	RB
cord-347000-zxytdb0b	225	6	reliable	reliable	JJ
cord-347000-zxytdb0b	225	7	but	but	CC
cord-347000-zxytdb0b	225	8	the	the	DT
cord-347000-zxytdb0b	225	9	use	use	NN
cord-347000-zxytdb0b	225	10	of	of	IN
cord-347000-zxytdb0b	225	11	selective	selective	JJ
cord-347000-zxytdb0b	225	12	culture	culture	NN
cord-347000-zxytdb0b	225	13	media	medium	NNS
cord-347000-zxytdb0b	225	14	and	and	CC
cord-347000-zxytdb0b	225	15	molecular	molecular	JJ
cord-347000-zxytdb0b	225	16	identification	identification	NN
cord-347000-zxytdb0b	225	17	methods	method	NNS
cord-347000-zxytdb0b	225	18	have	have	VBP
cord-347000-zxytdb0b	225	19	greatly	greatly	RB
cord-347000-zxytdb0b	225	20	improved	improve	VBN
cord-347000-zxytdb0b	225	21	detection	detection	NN
cord-347000-zxytdb0b	225	22	.	.	.
cord-347000-zxytdb0b	226	1	The	the	DT
cord-347000-zxytdb0b	226	2	epidemiology	epidemiology	NN
cord-347000-zxytdb0b	226	3	of	of	IN
cord-347000-zxytdb0b	226	4	B.	B.	NNP
cord-347000-zxytdb0b	226	5	pseudomallei	pseudomallei	NN
cord-347000-zxytdb0b	226	6	is	be	VBZ
cord-347000-zxytdb0b	226	7	totally	totally	RB
cord-347000-zxytdb0b	226	8	different	different	JJ
cord-347000-zxytdb0b	226	9	from	from	IN
cord-347000-zxytdb0b	226	10	Bcc	Bcc	NNP
cord-347000-zxytdb0b	226	11	.	.	.
cord-347000-zxytdb0b	227	1	This	this	DT
cord-347000-zxytdb0b	227	2	is	be	VBZ
cord-347000-zxytdb0b	227	3	a	a	DT
cord-347000-zxytdb0b	227	4	well	well	RB
cord-347000-zxytdb0b	227	5	-	-	HYPH
cord-347000-zxytdb0b	227	6	recognized	recognize	VBN
cord-347000-zxytdb0b	227	7	human	human	JJ
cord-347000-zxytdb0b	227	8	pathogen	pathogen	NN
cord-347000-zxytdb0b	227	9	that	that	WDT
cord-347000-zxytdb0b	227	10	can	can	MD
cord-347000-zxytdb0b	227	11	cause	cause	VB
cord-347000-zxytdb0b	227	12	melioidosis	melioidosis	NN
cord-347000-zxytdb0b	227	13	with	with	IN
cord-347000-zxytdb0b	227	14	severe	severe	JJ
cord-347000-zxytdb0b	227	15	pneumonia	pneumonia	NN
cord-347000-zxytdb0b	227	16	in	in	IN
cord-347000-zxytdb0b	227	17	individuals	individual	NNS
cord-347000-zxytdb0b	227	18	who	who	WP
cord-347000-zxytdb0b	227	19	are	be	VBP
cord-347000-zxytdb0b	227	20	immuno	immuno	JJ
cord-347000-zxytdb0b	227	21	-	-	JJ
cord-347000-zxytdb0b	227	22	competent	competent	JJ
cord-347000-zxytdb0b	227	23	and	and	CC
cord-347000-zxytdb0b	227	24	do	do	VBP
cord-347000-zxytdb0b	227	25	not	not	RB
cord-347000-zxytdb0b	227	26	have	have	VB
cord-347000-zxytdb0b	227	27	the	the	DT
cord-347000-zxytdb0b	227	28	CF	cf	NN
cord-347000-zxytdb0b	227	29	gene	gene	NN
cord-347000-zxytdb0b	227	30	defect	defect	NN
cord-347000-zxytdb0b	227	31	.	.	.
cord-347000-zxytdb0b	228	1	There	there	EX
cord-347000-zxytdb0b	228	2	are	be	VBP
cord-347000-zxytdb0b	228	3	reports	report	NNS
cord-347000-zxytdb0b	228	4	of	of	IN
cord-347000-zxytdb0b	228	5	infection	infection	NN
cord-347000-zxytdb0b	228	6	in	in	IN
cord-347000-zxytdb0b	228	7	CF	cf	NN
cord-347000-zxytdb0b	228	8	patients	patient	NNS
cord-347000-zxytdb0b	228	9	living	live	VBG
cord-347000-zxytdb0b	228	10	in	in	IN
cord-347000-zxytdb0b	228	11	or	or	CC
cord-347000-zxytdb0b	228	12	travelling	travel	VBG
cord-347000-zxytdb0b	228	13	to	to	IN
cord-347000-zxytdb0b	228	14	endemic	endemic	JJ
cord-347000-zxytdb0b	228	15	areas	area	NNS
cord-347000-zxytdb0b	228	16	.	.	.
cord-347000-zxytdb0b	229	1	45	45	CD
cord-347000-zxytdb0b	229	2	Not	not	RB
cord-347000-zxytdb0b	229	3	all	all	DT
cord-347000-zxytdb0b	229	4	infections	infection	NNS
cord-347000-zxytdb0b	229	5	lead	lead	VBP
cord-347000-zxytdb0b	229	6	to	to	IN
cord-347000-zxytdb0b	229	7	significant	significant	JJ
cord-347000-zxytdb0b	229	8	disease	disease	NN
cord-347000-zxytdb0b	229	9	.	.	.
cord-347000-zxytdb0b	230	1	The	the	DT
cord-347000-zxytdb0b	230	2	bacteria	bacteria	NNS
cord-347000-zxytdb0b	230	3	may	may	MD
cord-347000-zxytdb0b	230	4	however	however	RB
cord-347000-zxytdb0b	230	5	persist	persist	VB
cord-347000-zxytdb0b	230	6	in	in	IN
cord-347000-zxytdb0b	230	7	the	the	DT
cord-347000-zxytdb0b	230	8	CF	cf	NN
cord-347000-zxytdb0b	230	9	lung	lung	NN
cord-347000-zxytdb0b	230	10	with	with	IN
cord-347000-zxytdb0b	230	11	the	the	DT
cord-347000-zxytdb0b	230	12	risk	risk	NN
cord-347000-zxytdb0b	230	13	of	of	IN
cord-347000-zxytdb0b	230	14	later	later	JJ
cord-347000-zxytdb0b	230	15	reactivation	reactivation	NN
cord-347000-zxytdb0b	230	16	.	.	.
cord-347000-zxytdb0b	231	1	Other	other	JJ
cord-347000-zxytdb0b	231	2	Gram	gram	NN
cord-347000-zxytdb0b	231	3	-	-	HYPH
cord-347000-zxytdb0b	231	4	negative	negative	JJ
cord-347000-zxytdb0b	231	5	bacilli	bacilli	NN
cord-347000-zxytdb0b	231	6	(	(	-LRB-
cord-347000-zxytdb0b	232	1	e.g.	e.g.	RB
cord-347000-zxytdb0b	232	2	Achromobacter	Achromobacter	NNP
cord-347000-zxytdb0b	232	3	xylosoxidans	xylosoxidans	NNP
cord-347000-zxytdb0b	232	4	,	,	,
cord-347000-zxytdb0b	232	5	Stenotrophomonas	Stenotrophomonas	NNP
cord-347000-zxytdb0b	232	6	maltophilia	maltophilia	NNP
cord-347000-zxytdb0b	232	7	,	,	,
cord-347000-zxytdb0b	232	8	Pandoraea	Pandoraea	NNP
cord-347000-zxytdb0b	232	9	apista	apista	NN
cord-347000-zxytdb0b	232	10	)	)	-RRB-
cord-347000-zxytdb0b	233	1	Some	some	DT
cord-347000-zxytdb0b	233	2	Gram	gram	NN
cord-347000-zxytdb0b	233	3	-	-	HYPH
cord-347000-zxytdb0b	233	4	negative	negative	JJ
cord-347000-zxytdb0b	233	5	bacilli	bacilli	NN
cord-347000-zxytdb0b	233	6	are	be	VBP
cord-347000-zxytdb0b	233	7	either	either	CC
cord-347000-zxytdb0b	233	8	more	more	RBR
cord-347000-zxytdb0b	233	9	prevalent	prevalent	JJ
cord-347000-zxytdb0b	233	10	in	in	IN
cord-347000-zxytdb0b	233	11	CF	CF	NNP
cord-347000-zxytdb0b	233	12	now	now	RB
cord-347000-zxytdb0b	233	13	(	(	-LRB-
cord-347000-zxytdb0b	233	14	S.	S.	NNP
cord-347000-zxytdb0b	233	15	maltophilia	maltophilia	NNP
cord-347000-zxytdb0b	233	16	)	)	-RRB-
cord-347000-zxytdb0b	233	17	or	or	CC
cord-347000-zxytdb0b	233	18	have	have	VBP
cord-347000-zxytdb0b	233	19	been	be	VBN
cord-347000-zxytdb0b	233	20	recognized	recognize	VBN
cord-347000-zxytdb0b	233	21	more	more	RBR
cord-347000-zxytdb0b	233	22	recently	recently	RB
cord-347000-zxytdb0b	233	23	due	due	JJ
cord-347000-zxytdb0b	233	24	to	to	IN
cord-347000-zxytdb0b	233	25	improvements	improvement	NNS
cord-347000-zxytdb0b	233	26	in	in	IN
cord-347000-zxytdb0b	233	27	laboratory	laboratory	NN
cord-347000-zxytdb0b	233	28	identification	identification	NN
cord-347000-zxytdb0b	233	29	(	(	-LRB-
cord-347000-zxytdb0b	233	30	A.	A.	NNP
cord-347000-zxytdb0b	233	31	xylosoxidans	xylosoxidan	NNS
cord-347000-zxytdb0b	233	32	,	,	,
cord-347000-zxytdb0b	233	33	Pandoraea	Pandoraea	NNP
cord-347000-zxytdb0b	233	34	apista	apista	NN
cord-347000-zxytdb0b	233	35	)	)	-RRB-
cord-347000-zxytdb0b	233	36	.	.	.
cord-347000-zxytdb0b	234	1	These	these	DT
cord-347000-zxytdb0b	234	2	bacteria	bacteria	NNS
cord-347000-zxytdb0b	234	3	may	may	MD
cord-347000-zxytdb0b	234	4	have	have	VB
cord-347000-zxytdb0b	234	5	been	be	VBN
cord-347000-zxytdb0b	234	6	selected	select	VBN
cord-347000-zxytdb0b	234	7	by	by	IN
cord-347000-zxytdb0b	234	8	prolonged	prolong	VBN
cord-347000-zxytdb0b	234	9	use	use	NN
cord-347000-zxytdb0b	234	10	of	of	IN
cord-347000-zxytdb0b	234	11	antipseudomonal	antipseudomonal	JJ
cord-347000-zxytdb0b	234	12	antibiotics	antibiotic	NNS
cord-347000-zxytdb0b	234	13	with	with	IN
cord-347000-zxytdb0b	234	14	the	the	DT
cord-347000-zxytdb0b	234	15	increasing	increase	VBG
cord-347000-zxytdb0b	234	16	life	life	NN
cord-347000-zxytdb0b	234	17	expectancy	expectancy	NN
cord-347000-zxytdb0b	234	18	of	of	IN
cord-347000-zxytdb0b	234	19	CF	CF	NNP
cord-347000-zxytdb0b	234	20	patients	patient	NNS
cord-347000-zxytdb0b	234	21	.	.	.
cord-347000-zxytdb0b	235	1	Recent	recent	JJ
cord-347000-zxytdb0b	235	2	studies	study	NNS
cord-347000-zxytdb0b	235	3	of	of	IN
cord-347000-zxytdb0b	235	4	S.	S.	NNP
cord-347000-zxytdb0b	235	5	maltophilia	maltophilia	NNP
cord-347000-zxytdb0b	235	6	support	support	NN
cord-347000-zxytdb0b	235	7	earlier	early	JJR
cord-347000-zxytdb0b	235	8	observations	observation	NNS
cord-347000-zxytdb0b	235	9	that	that	IN
cord-347000-zxytdb0b	235	10	this	this	DT
cord-347000-zxytdb0b	235	11	organism	organism	NN
cord-347000-zxytdb0b	235	12	may	may	MD
cord-347000-zxytdb0b	235	13	be	be	VB
cord-347000-zxytdb0b	235	14	of	of	IN
cord-347000-zxytdb0b	235	15	limited	limited	JJ
cord-347000-zxytdb0b	235	16	clinical	clinical	JJ
cord-347000-zxytdb0b	235	17	significance	significance	NN
cord-347000-zxytdb0b	235	18	in	in	IN
cord-347000-zxytdb0b	235	19	CF	CF	NNP
cord-347000-zxytdb0b	235	20	.	.	.
cord-347000-zxytdb0b	236	1	46	46	CD
cord-347000-zxytdb0b	237	1	Despite	despite	IN
cord-347000-zxytdb0b	237	2	increasing	increase	VBG
cord-347000-zxytdb0b	237	3	culture	culture	NN
cord-347000-zxytdb0b	237	4	from	from	IN
cord-347000-zxytdb0b	237	5	CF	cf	NN
cord-347000-zxytdb0b	237	6	patients	patient	NNS
cord-347000-zxytdb0b	237	7	with	with	IN
cord-347000-zxytdb0b	237	8	more	more	RBR
cord-347000-zxytdb0b	237	9	severe	severe	JJ
cord-347000-zxytdb0b	237	10	disease	disease	NN
cord-347000-zxytdb0b	237	11	,	,	,
cord-347000-zxytdb0b	237	12	it	-PRON-	PRP
cord-347000-zxytdb0b	237	13	is	be	VBZ
cord-347000-zxytdb0b	237	14	not	not	RB
cord-347000-zxytdb0b	237	15	associated	associate	VBN
cord-347000-zxytdb0b	237	16	with	with	IN
cord-347000-zxytdb0b	237	17	pulmonary	pulmonary	JJ
cord-347000-zxytdb0b	237	18	deterioration	deterioration	NN
cord-347000-zxytdb0b	237	19	.	.	.
cord-347000-zxytdb0b	238	1	It	-PRON-	PRP
cord-347000-zxytdb0b	238	2	is	be	VBZ
cord-347000-zxytdb0b	238	3	intrinsically	intrinsically	RB
cord-347000-zxytdb0b	238	4	resistant	resistant	JJ
cord-347000-zxytdb0b	238	5	to	to	IN
cord-347000-zxytdb0b	238	6	meropenem	meropenem	NNP
cord-347000-zxytdb0b	238	7	and	and	CC
cord-347000-zxytdb0b	238	8	can	can	MD
cord-347000-zxytdb0b	238	9	acquire	acquire	VB
cord-347000-zxytdb0b	238	10	resistance	resistance	NN
cord-347000-zxytdb0b	238	11	to	to	IN
cord-347000-zxytdb0b	238	12	many	many	JJ
cord-347000-zxytdb0b	238	13	other	other	JJ
cord-347000-zxytdb0b	238	14	antibiotics	antibiotic	NNS
cord-347000-zxytdb0b	238	15	.	.	.
cord-347000-zxytdb0b	239	1	While	while	IN
cord-347000-zxytdb0b	239	2	co	co	JJ
cord-347000-zxytdb0b	239	3	-	-	JJ
cord-347000-zxytdb0b	239	4	trimoxazole	trimoxazole	NNP
cord-347000-zxytdb0b	239	5	is	be	VBZ
cord-347000-zxytdb0b	239	6	the	the	DT
cord-347000-zxytdb0b	239	7	treatment	treatment	NN
cord-347000-zxytdb0b	239	8	of	of	IN
cord-347000-zxytdb0b	239	9	choice	choice	NN
cord-347000-zxytdb0b	239	10	in	in	IN
cord-347000-zxytdb0b	239	11	symptomatic	symptomatic	JJ
cord-347000-zxytdb0b	239	12	infection	infection	NN
cord-347000-zxytdb0b	239	13	,	,	,
cord-347000-zxytdb0b	239	14	the	the	DT
cord-347000-zxytdb0b	239	15	best	good	JJS
cord-347000-zxytdb0b	239	16	management	management	NN
cord-347000-zxytdb0b	239	17	of	of	IN
cord-347000-zxytdb0b	239	18	co	co	JJ
cord-347000-zxytdb0b	239	19	-	-	JJ
cord-347000-zxytdb0b	239	20	trimoxazole	trimoxazole	JJ
cord-347000-zxytdb0b	239	21	-	-	HYPH
cord-347000-zxytdb0b	239	22	resistant	resistant	JJ
cord-347000-zxytdb0b	239	23	infections	infection	NNS
cord-347000-zxytdb0b	239	24	is	be	VBZ
cord-347000-zxytdb0b	239	25	uncertain	uncertain	JJ
cord-347000-zxytdb0b	239	26	and	and	CC
cord-347000-zxytdb0b	239	27	in	in	IN
cord-347000-zxytdb0b	239	28	vitro	vitro	FW
cord-347000-zxytdb0b	239	29	susceptibility	susceptibility	NN
cord-347000-zxytdb0b	239	30	testing	testing	NN
cord-347000-zxytdb0b	239	31	of	of	IN
cord-347000-zxytdb0b	239	32	other	other	JJ
cord-347000-zxytdb0b	239	33	agents	agent	NNS
cord-347000-zxytdb0b	239	34	with	with	IN
cord-347000-zxytdb0b	239	35	current	current	JJ
cord-347000-zxytdb0b	239	36	methods	method	NNS
cord-347000-zxytdb0b	239	37	is	be	VBZ
cord-347000-zxytdb0b	239	38	not	not	RB
cord-347000-zxytdb0b	239	39	reliable	reliable	JJ
cord-347000-zxytdb0b	239	40	enough	enough	RB
cord-347000-zxytdb0b	239	41	to	to	TO
cord-347000-zxytdb0b	239	42	be	be	VB
cord-347000-zxytdb0b	239	43	used	use	VBN
cord-347000-zxytdb0b	239	44	to	to	TO
cord-347000-zxytdb0b	239	45	determine	determine	VB
cord-347000-zxytdb0b	239	46	treatment	treatment	NN
cord-347000-zxytdb0b	239	47	.	.	.
cord-347000-zxytdb0b	240	1	Like	like	IN
cord-347000-zxytdb0b	240	2	Stenotrophomonas	Stenotrophomonas	NNP
cord-347000-zxytdb0b	240	3	,	,	,
cord-347000-zxytdb0b	240	4	Achromobacter	Achromobacter	NNP
cord-347000-zxytdb0b	240	5	(	(	-LRB-
cord-347000-zxytdb0b	240	6	previously	previously	RB
cord-347000-zxytdb0b	240	7	Alcaligenes	Alcaligenes	NNPS
cord-347000-zxytdb0b	240	8	)	)	-RRB-
cord-347000-zxytdb0b	240	9	xylosoxidans	xylosoxidans	NNP
cord-347000-zxytdb0b	240	10	may	may	MD
cord-347000-zxytdb0b	240	11	chronically	chronically	RB
cord-347000-zxytdb0b	240	12	colonize	colonize	VB
cord-347000-zxytdb0b	240	13	the	the	DT
cord-347000-zxytdb0b	240	14	CF	cf	NN
cord-347000-zxytdb0b	240	15	lung	lung	NN
cord-347000-zxytdb0b	240	16	but	but	CC
cord-347000-zxytdb0b	240	17	has	have	VBZ
cord-347000-zxytdb0b	240	18	not	not	RB
cord-347000-zxytdb0b	240	19	been	be	VBN
cord-347000-zxytdb0b	240	20	shown	show	VBN
cord-347000-zxytdb0b	240	21	to	to	TO
cord-347000-zxytdb0b	240	22	lead	lead	VB
cord-347000-zxytdb0b	240	23	to	to	IN
cord-347000-zxytdb0b	240	24	significant	significant	JJ
cord-347000-zxytdb0b	240	25	deterioration	deterioration	NN
cord-347000-zxytdb0b	240	26	in	in	IN
cord-347000-zxytdb0b	240	27	lung	lung	NN
cord-347000-zxytdb0b	240	28	function	function	NN
cord-347000-zxytdb0b	240	29	,	,	,
cord-347000-zxytdb0b	240	30	but	but	CC
cord-347000-zxytdb0b	240	31	more	more	JJR
cord-347000-zxytdb0b	240	32	data	datum	NNS
cord-347000-zxytdb0b	240	33	are	be	VBP
cord-347000-zxytdb0b	240	34	needed	need	VBN
cord-347000-zxytdb0b	240	35	.	.	.
cord-347000-zxytdb0b	241	1	47	47	CD
cord-347000-zxytdb0b	242	1	Pandoraea	Pandoraea	NNP
cord-347000-zxytdb0b	242	2	apista	apista	NN
cord-347000-zxytdb0b	242	3	has	have	VBZ
cord-347000-zxytdb0b	242	4	only	only	RB
cord-347000-zxytdb0b	242	5	recently	recently	RB
cord-347000-zxytdb0b	242	6	been	be	VBN
cord-347000-zxytdb0b	242	7	identified	identify	VBN
cord-347000-zxytdb0b	242	8	in	in	IN
cord-347000-zxytdb0b	242	9	CF	cf	NN
cord-347000-zxytdb0b	242	10	sputum	sputum	NN
cord-347000-zxytdb0b	242	11	.	.	.
cord-347000-zxytdb0b	243	1	As	as	IN
cord-347000-zxytdb0b	243	2	it	-PRON-	PRP
cord-347000-zxytdb0b	243	3	is	be	VBZ
cord-347000-zxytdb0b	243	4	intrinsically	intrinsically	RB
cord-347000-zxytdb0b	243	5	resistant	resistant	JJ
cord-347000-zxytdb0b	243	6	to	to	IN
cord-347000-zxytdb0b	243	7	colistin	colistin	NNP
cord-347000-zxytdb0b	243	8	,	,	,
cord-347000-zxytdb0b	243	9	it	-PRON-	PRP
cord-347000-zxytdb0b	243	10	may	may	MD
cord-347000-zxytdb0b	243	11	also	also	RB
cord-347000-zxytdb0b	243	12	be	be	VB
cord-347000-zxytdb0b	243	13	mis	mi	VBN
cord-347000-zxytdb0b	243	14	-	-	:
cord-347000-zxytdb0b	243	15	identified	identify	VBN
cord-347000-zxytdb0b	243	16	as	as	IN
cord-347000-zxytdb0b	243	17	a	a	DT
cord-347000-zxytdb0b	243	18	Burkholderia	Burkholderia	NNP
cord-347000-zxytdb0b	243	19	sp	sp	NN
cord-347000-zxytdb0b	243	20	.	.	.
cord-347000-zxytdb0b	244	1	More	More	JJR
cord-347000-zxytdb0b	244	2	information	information	NN
cord-347000-zxytdb0b	244	3	on	on	IN
cord-347000-zxytdb0b	244	4	the	the	DT
cord-347000-zxytdb0b	244	5	clinical	clinical	JJ
cord-347000-zxytdb0b	244	6	relevance	relevance	NN
cord-347000-zxytdb0b	244	7	of	of	IN
cord-347000-zxytdb0b	244	8	this	this	DT
cord-347000-zxytdb0b	244	9	organism	organism	NN
cord-347000-zxytdb0b	244	10	is	be	VBZ
cord-347000-zxytdb0b	244	11	needed	need	VBN
cord-347000-zxytdb0b	244	12	,	,	,
cord-347000-zxytdb0b	244	13	but	but	CC
cord-347000-zxytdb0b	244	14	cross	cross	NN
cord-347000-zxytdb0b	244	15	-	-	NN
cord-347000-zxytdb0b	244	16	infection	infection	NN
cord-347000-zxytdb0b	244	17	with	with	IN
cord-347000-zxytdb0b	244	18	clinical	clinical	JJ
cord-347000-zxytdb0b	244	19	deterioration	deterioration	NN
cord-347000-zxytdb0b	244	20	has	have	VBZ
cord-347000-zxytdb0b	244	21	been	be	VBN
cord-347000-zxytdb0b	244	22	described	describe	VBN
cord-347000-zxytdb0b	244	23	in	in	IN
cord-347000-zxytdb0b	244	24	six	six	CD
cord-347000-zxytdb0b	244	25	patients	patient	NNS
cord-347000-zxytdb0b	244	26	in	in	IN
cord-347000-zxytdb0b	244	27	a	a	DT
cord-347000-zxytdb0b	244	28	Danish	danish	JJ
cord-347000-zxytdb0b	244	29	CF	cf	NN
cord-347000-zxytdb0b	244	30	centre	centre	NN
cord-347000-zxytdb0b	244	31	.	.	.
cord-347000-zxytdb0b	245	1	48	48	CD
cord-347000-zxytdb0b	246	1	A	a	DT
cord-347000-zxytdb0b	246	2	wide	wide	JJ
cord-347000-zxytdb0b	246	3	range	range	NN
cord-347000-zxytdb0b	246	4	of	of	IN
cord-347000-zxytdb0b	246	5	other	other	JJ
cord-347000-zxytdb0b	246	6	Gram	gram	NN
cord-347000-zxytdb0b	246	7	-	-	HYPH
cord-347000-zxytdb0b	246	8	negative	negative	JJ
cord-347000-zxytdb0b	246	9	bacteria	bacteria	NNS
cord-347000-zxytdb0b	246	10	can	can	MD
cord-347000-zxytdb0b	246	11	be	be	VB
cord-347000-zxytdb0b	246	12	isolated	isolate	VBN
cord-347000-zxytdb0b	246	13	from	from	IN
cord-347000-zxytdb0b	246	14	CF	cf	NN
cord-347000-zxytdb0b	246	15	sputum	sputum	NN
cord-347000-zxytdb0b	246	16	including	include	VBG
cord-347000-zxytdb0b	246	17	species	specie	NNS
cord-347000-zxytdb0b	246	18	of	of	IN
cord-347000-zxytdb0b	246	19	the	the	DT
cord-347000-zxytdb0b	246	20	genera	genera	NNP
cord-347000-zxytdb0b	246	21	Ralstonia	Ralstonia	NNP
cord-347000-zxytdb0b	246	22	,	,	,
cord-347000-zxytdb0b	246	23	Chryseobacterium	Chryseobacterium	NNP
cord-347000-zxytdb0b	246	24	,	,	,
cord-347000-zxytdb0b	246	25	Comamonas	Comamonas	NNP
cord-347000-zxytdb0b	246	26	,	,	,
cord-347000-zxytdb0b	246	27	Moraxella	Moraxella	NNP
cord-347000-zxytdb0b	246	28	,	,	,
cord-347000-zxytdb0b	246	29	Acinetobacter	Acinetobacter	NNP
cord-347000-zxytdb0b	246	30	,	,	,
cord-347000-zxytdb0b	246	31	Bordetella	Bordetella	NNP
cord-347000-zxytdb0b	246	32	,	,	,
cord-347000-zxytdb0b	246	33	Inquilinus	Inquilinus	NNP
cord-347000-zxytdb0b	246	34	and	and	CC
cord-347000-zxytdb0b	246	35	members	member	NNS
cord-347000-zxytdb0b	246	36	of	of	IN
cord-347000-zxytdb0b	246	37	the	the	DT
cord-347000-zxytdb0b	246	38	family	family	NN
cord-347000-zxytdb0b	246	39	Enterobacteriaceae	Enterobacteriaceae	NNP
cord-347000-zxytdb0b	246	40	.	.	.
cord-347000-zxytdb0b	247	1	49	49	CD
cord-347000-zxytdb0b	248	1	There	there	EX
cord-347000-zxytdb0b	248	2	are	be	VBP
cord-347000-zxytdb0b	248	3	insufficient	insufficient	JJ
cord-347000-zxytdb0b	248	4	data	datum	NNS
cord-347000-zxytdb0b	248	5	to	to	TO
cord-347000-zxytdb0b	248	6	comment	comment	VB
cord-347000-zxytdb0b	248	7	on	on	IN
cord-347000-zxytdb0b	248	8	the	the	DT
cord-347000-zxytdb0b	248	9	clinical	clinical	JJ
cord-347000-zxytdb0b	248	10	relevance	relevance	NN
cord-347000-zxytdb0b	248	11	of	of	IN
cord-347000-zxytdb0b	248	12	these	these	DT
cord-347000-zxytdb0b	248	13	bacteria	bacteria	NNS
cord-347000-zxytdb0b	248	14	and	and	CC
cord-347000-zxytdb0b	248	15	they	-PRON-	PRP
cord-347000-zxytdb0b	248	16	may	may	MD
cord-347000-zxytdb0b	248	17	be	be	VB
cord-347000-zxytdb0b	248	18	harmless	harmless	JJ
cord-347000-zxytdb0b	248	19	colonizers	colonizer	NNS
cord-347000-zxytdb0b	248	20	.	.	.
cord-347000-zxytdb0b	249	1	It	-PRON-	PRP
cord-347000-zxytdb0b	249	2	is	be	VBZ
cord-347000-zxytdb0b	249	3	important	important	JJ
cord-347000-zxytdb0b	249	4	however	however	RB
cord-347000-zxytdb0b	249	5	that	that	IN
cord-347000-zxytdb0b	249	6	they	-PRON-	PRP
cord-347000-zxytdb0b	249	7	are	be	VBP
cord-347000-zxytdb0b	249	8	correctly	correctly	RB
cord-347000-zxytdb0b	249	9	identified	identify	VBN
cord-347000-zxytdb0b	249	10	.	.	.
cord-347000-zxytdb0b	250	1	This	this	DT
cord-347000-zxytdb0b	250	2	is	be	VBZ
cord-347000-zxytdb0b	250	3	so	so	IN
cord-347000-zxytdb0b	250	4	that	that	IN
cord-347000-zxytdb0b	250	5	any	any	DT
cord-347000-zxytdb0b	250	6	association	association	NN
cord-347000-zxytdb0b	250	7	with	with	IN
cord-347000-zxytdb0b	250	8	significant	significant	JJ
cord-347000-zxytdb0b	250	9	disease	disease	NN
cord-347000-zxytdb0b	250	10	may	may	MD
cord-347000-zxytdb0b	250	11	be	be	VB
cord-347000-zxytdb0b	250	12	recognized	recognize	VBN
cord-347000-zxytdb0b	250	13	but	but	CC
cord-347000-zxytdb0b	250	14	also	also	RB
cord-347000-zxytdb0b	250	15	because	because	IN
cord-347000-zxytdb0b	250	16	some	some	DT
cord-347000-zxytdb0b	250	17	may	may	MD
cord-347000-zxytdb0b	250	18	be	be	VB
cord-347000-zxytdb0b	250	19	mistaken	mistake	VBN
cord-347000-zxytdb0b	250	20	for	for	IN
cord-347000-zxytdb0b	250	21	known	know	VBN
cord-347000-zxytdb0b	250	22	pathogens	pathogen	NNS
cord-347000-zxytdb0b	250	23	.	.	.
cord-347000-zxytdb0b	251	1	UK	UK	NNP
cord-347000-zxytdb0b	251	2	reference	reference	NN
cord-347000-zxytdb0b	251	3	laboratory	laboratory	NN
cord-347000-zxytdb0b	251	4	reports	report	NNS
cord-347000-zxytdb0b	251	5	suggest	suggest	VBP
cord-347000-zxytdb0b	251	6	that	that	IN
cord-347000-zxytdb0b	251	7	around	around	IN
cord-347000-zxytdb0b	251	8	10	10	CD
cord-347000-zxytdb0b	251	9	%	%	NN
cord-347000-zxytdb0b	251	10	bacteria	bacteria	NNS
cord-347000-zxytdb0b	251	11	referred	refer	VBN
cord-347000-zxytdb0b	251	12	as	as	IN
cord-347000-zxytdb0b	251	13	members	member	NNS
cord-347000-zxytdb0b	251	14	of	of	IN
cord-347000-zxytdb0b	251	15	the	the	DT
cord-347000-zxytdb0b	251	16	Bcc	Bcc	NNP
cord-347000-zxytdb0b	251	17	were	be	VBD
cord-347000-zxytdb0b	251	18	initially	initially	RB
cord-347000-zxytdb0b	251	19	mis	mi	VBN
cord-347000-zxytdb0b	251	20	-	-	VBN
cord-347000-zxytdb0b	251	21	identified	identify	VBN
cord-347000-zxytdb0b	251	22	.	.	.
cord-347000-zxytdb0b	252	1	A	a	DT
cord-347000-zxytdb0b	252	2	similar	similar	JJ
cord-347000-zxytdb0b	252	3	mis	mis	NN
cord-347000-zxytdb0b	252	4	-	-	HYPH
cord-347000-zxytdb0b	252	5	identification	identification	NN
cord-347000-zxytdb0b	252	6	rate	rate	NN
cord-347000-zxytdb0b	252	7	occurs	occur	VBZ
cord-347000-zxytdb0b	252	8	between	between	IN
cord-347000-zxytdb0b	252	9	A.	a.	NN
cord-347000-zxytdb0b	252	10	xylosoxidans	xylosoxidan	NNS
cord-347000-zxytdb0b	252	11	and	and	CC
cord-347000-zxytdb0b	252	12	atypical	atypical	JJ
cord-347000-zxytdb0b	252	13	multi	multi	JJ
cord-347000-zxytdb0b	252	14	-	-	JJ
cord-347000-zxytdb0b	252	15	resistant	resistant	JJ
cord-347000-zxytdb0b	252	16	forms	form	NNS
cord-347000-zxytdb0b	252	17	of	of	IN
cord-347000-zxytdb0b	252	18	P.	P.	NNP
cord-347000-zxytdb0b	252	19	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	252	20	.	.	.
cord-347000-zxytdb0b	253	1	A	a	DT
cord-347000-zxytdb0b	253	2	recent	recent	JJ
cord-347000-zxytdb0b	253	3	paper	paper	NN
cord-347000-zxytdb0b	253	4	highlights	highlight	VBZ
cord-347000-zxytdb0b	253	5	the	the	DT
cord-347000-zxytdb0b	253	6	difficulty	difficulty	NN
cord-347000-zxytdb0b	253	7	identifying	identify	VBG
cord-347000-zxytdb0b	253	8	CF	CF	NNP
cord-347000-zxytdb0b	253	9	bacteria	bacteria	NNS
cord-347000-zxytdb0b	253	10	with	with	IN
cord-347000-zxytdb0b	253	11	atypical	atypical	JJ
cord-347000-zxytdb0b	253	12	phenotypes	phenotype	NNS
cord-347000-zxytdb0b	253	13	using	use	VBG
cord-347000-zxytdb0b	253	14	traditional	traditional	JJ
cord-347000-zxytdb0b	253	15	methods	method	NNS
cord-347000-zxytdb0b	253	16	(	(	-LRB-
cord-347000-zxytdb0b	253	17	colony	colony	NN
cord-347000-zxytdb0b	253	18	morphology	morphology	NN
cord-347000-zxytdb0b	253	19	and	and	CC
cord-347000-zxytdb0b	253	20	biochemical	biochemical	JJ
cord-347000-zxytdb0b	253	21	identification	identification	NN
cord-347000-zxytdb0b	253	22	)	)	-RRB-
cord-347000-zxytdb0b	253	23	and	and	CC
cord-347000-zxytdb0b	253	24	the	the	DT
cord-347000-zxytdb0b	253	25	authors	author	NNS
cord-347000-zxytdb0b	253	26	advocate	advocate	VBP
cord-347000-zxytdb0b	253	27	the	the	DT
cord-347000-zxytdb0b	253	28	use	use	NN
cord-347000-zxytdb0b	253	29	of	of	IN
cord-347000-zxytdb0b	253	30	nucleic	nucleic	JJ
cord-347000-zxytdb0b	253	31	acid	acid	NN
cord-347000-zxytdb0b	253	32	-	-	HYPH
cord-347000-zxytdb0b	253	33	based	base	VBN
cord-347000-zxytdb0b	253	34	identification	identification	NN
cord-347000-zxytdb0b	253	35	methods	method	NNS
cord-347000-zxytdb0b	253	36	such	such	JJ
cord-347000-zxytdb0b	253	37	as	as	IN
cord-347000-zxytdb0b	253	38	species	species	NN
cord-347000-zxytdb0b	253	39	-	-	HYPH
cord-347000-zxytdb0b	253	40	specific	specific	JJ
cord-347000-zxytdb0b	253	41	PCR	PCR	NNP
cord-347000-zxytdb0b	253	42	or	or	CC
cord-347000-zxytdb0b	253	43	ribosomal	ribosomal	JJ
cord-347000-zxytdb0b	253	44	RNA	RNA	NNP
cord-347000-zxytdb0b	253	45	gene	gene	NN
cord-347000-zxytdb0b	253	46	sequencing	sequencing	NN
cord-347000-zxytdb0b	253	47	.	.	.
cord-347000-zxytdb0b	254	1	50	50	CD
cord-347000-zxytdb0b	254	2	Non	non	JJ
cord-347000-zxytdb0b	254	3	-	-	JJ
cord-347000-zxytdb0b	254	4	tuberculous	tuberculous	JJ
cord-347000-zxytdb0b	254	5	mycobacteria	mycobacterium	NNS
cord-347000-zxytdb0b	254	6	(	(	-LRB-
cord-347000-zxytdb0b	254	7	NTM	NTM	NNP
cord-347000-zxytdb0b	254	8	)	)	-RRB-
cord-347000-zxytdb0b	254	9	are	be	VBP
cord-347000-zxytdb0b	254	10	being	be	VBG
cord-347000-zxytdb0b	254	11	increasingly	increasingly	RB
cord-347000-zxytdb0b	254	12	recognized	recognize	VBN
cord-347000-zxytdb0b	254	13	as	as	IN
cord-347000-zxytdb0b	254	14	a	a	DT
cord-347000-zxytdb0b	254	15	cause	cause	NN
cord-347000-zxytdb0b	254	16	of	of	IN
cord-347000-zxytdb0b	254	17	infection	infection	NN
cord-347000-zxytdb0b	254	18	in	in	IN
cord-347000-zxytdb0b	254	19	CF	CF	NNP
cord-347000-zxytdb0b	254	20	.	.	.
cord-347000-zxytdb0b	255	1	This	this	DT
cord-347000-zxytdb0b	255	2	may	may	MD
cord-347000-zxytdb0b	255	3	be	be	VB
cord-347000-zxytdb0b	255	4	partly	partly	RB
cord-347000-zxytdb0b	255	5	because	because	IN
cord-347000-zxytdb0b	255	6	more	more	JJR
cord-347000-zxytdb0b	255	7	clinicians	clinician	NNS
cord-347000-zxytdb0b	255	8	are	be	VBP
cord-347000-zxytdb0b	255	9	sending	send	VBG
cord-347000-zxytdb0b	255	10	samples	sample	NNS
cord-347000-zxytdb0b	255	11	for	for	IN
cord-347000-zxytdb0b	255	12	NTM	NTM	NNP
cord-347000-zxytdb0b	255	13	culture	culture	NN
cord-347000-zxytdb0b	255	14	and	and	CC
cord-347000-zxytdb0b	255	15	laboratories	laboratory	NNS
cord-347000-zxytdb0b	255	16	are	be	VBP
cord-347000-zxytdb0b	255	17	getting	get	VBG
cord-347000-zxytdb0b	255	18	better	well	JJR
cord-347000-zxytdb0b	255	19	at	at	IN
cord-347000-zxytdb0b	255	20	isolating	isolate	VBG
cord-347000-zxytdb0b	255	21	NTM	NTM	NNP
cord-347000-zxytdb0b	255	22	.	.	.
cord-347000-zxytdb0b	256	1	However	however	RB
cord-347000-zxytdb0b	256	2	,	,	,
cord-347000-zxytdb0b	256	3	there	there	EX
cord-347000-zxytdb0b	256	4	is	be	VBZ
cord-347000-zxytdb0b	256	5	also	also	RB
cord-347000-zxytdb0b	256	6	thought	think	VBN
cord-347000-zxytdb0b	256	7	to	to	TO
cord-347000-zxytdb0b	256	8	be	be	VB
cord-347000-zxytdb0b	256	9	a	a	DT
cord-347000-zxytdb0b	256	10	genuine	genuine	JJ
cord-347000-zxytdb0b	256	11	increase	increase	NN
cord-347000-zxytdb0b	256	12	in	in	IN
cord-347000-zxytdb0b	256	13	the	the	DT
cord-347000-zxytdb0b	256	14	prevalence	prevalence	NN
cord-347000-zxytdb0b	256	15	of	of	IN
cord-347000-zxytdb0b	256	16	lung	lung	NN
cord-347000-zxytdb0b	256	17	infection	infection	NN
cord-347000-zxytdb0b	256	18	with	with	IN
cord-347000-zxytdb0b	256	19	NTM	NTM	NNP
cord-347000-zxytdb0b	256	20	as	as	IN
cord-347000-zxytdb0b	256	21	patients	patient	NNS
cord-347000-zxytdb0b	256	22	with	with	IN
cord-347000-zxytdb0b	256	23	CF	CF	NNP
cord-347000-zxytdb0b	256	24	survive	survive	VBP
cord-347000-zxytdb0b	256	25	longer	long	RBR
cord-347000-zxytdb0b	256	26	.	.	.
cord-347000-zxytdb0b	257	1	Automated	automate	VBN
cord-347000-zxytdb0b	257	2	liquid	liquid	JJ
cord-347000-zxytdb0b	257	3	systems	system	NNS
cord-347000-zxytdb0b	257	4	allow	allow	VBP
cord-347000-zxytdb0b	257	5	more	more	RBR
cord-347000-zxytdb0b	257	6	rapid	rapid	JJ
cord-347000-zxytdb0b	257	7	culture	culture	NN
cord-347000-zxytdb0b	257	8	of	of	IN
cord-347000-zxytdb0b	257	9	NTM	NTM	NNP
cord-347000-zxytdb0b	257	10	and	and	CC
cord-347000-zxytdb0b	257	11	may	may	MD
cord-347000-zxytdb0b	257	12	be	be	VB
cord-347000-zxytdb0b	257	13	more	more	RBR
cord-347000-zxytdb0b	257	14	sensitive	sensitive	JJ
cord-347000-zxytdb0b	257	15	than	than	IN
cord-347000-zxytdb0b	257	16	the	the	DT
cord-347000-zxytdb0b	257	17	traditional	traditional	JJ
cord-347000-zxytdb0b	257	18	use	use	NN
cord-347000-zxytdb0b	257	19	of	of	IN
cord-347000-zxytdb0b	257	20	Lowenstein	Lowenstein	NNP
cord-347000-zxytdb0b	257	21	Jensen	Jensen	NNP
cord-347000-zxytdb0b	257	22	agar	agar	NN
cord-347000-zxytdb0b	257	23	slopes	slope	NNS
cord-347000-zxytdb0b	257	24	.	.	.
cord-347000-zxytdb0b	258	1	The	the	DT
cord-347000-zxytdb0b	258	2	high	high	JJ
cord-347000-zxytdb0b	258	3	number	number	NN
cord-347000-zxytdb0b	258	4	of	of	IN
cord-347000-zxytdb0b	258	5	P.	P.	NNP
cord-347000-zxytdb0b	258	6	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	258	7	in	in	IN
cord-347000-zxytdb0b	258	8	CF	cf	NN
cord-347000-zxytdb0b	258	9	sputum	sputum	NN
cord-347000-zxytdb0b	258	10	can	can	MD
cord-347000-zxytdb0b	258	11	however	however	RB
cord-347000-zxytdb0b	258	12	cause	cause	VB
cord-347000-zxytdb0b	258	13	problems	problem	NNS
cord-347000-zxytdb0b	258	14	with	with	IN
cord-347000-zxytdb0b	258	15	decontamination	decontamination	NN
cord-347000-zxytdb0b	258	16	and	and	CC
cord-347000-zxytdb0b	258	17	make	make	VB
cord-347000-zxytdb0b	258	18	NTM	NTM	NNP
cord-347000-zxytdb0b	258	19	culture	culture	NN
cord-347000-zxytdb0b	258	20	difficult	difficult	JJ
cord-347000-zxytdb0b	258	21	.	.	.
cord-347000-zxytdb0b	259	1	51	51	CD
cord-347000-zxytdb0b	259	2	NTM	NTM	NNP
cord-347000-zxytdb0b	259	3	are	be	VBP
cord-347000-zxytdb0b	259	4	ubiquitous	ubiquitous	JJ
cord-347000-zxytdb0b	259	5	in	in	IN
cord-347000-zxytdb0b	259	6	the	the	DT
cord-347000-zxytdb0b	259	7	environment	environment	NN
cord-347000-zxytdb0b	259	8	and	and	CC
cord-347000-zxytdb0b	259	9	can	can	MD
cord-347000-zxytdb0b	259	10	be	be	VB
cord-347000-zxytdb0b	259	11	found	find	VBN
cord-347000-zxytdb0b	259	12	in	in	IN
cord-347000-zxytdb0b	259	13	dust	dust	NN
cord-347000-zxytdb0b	259	14	,	,	,
cord-347000-zxytdb0b	259	15	food	food	NN
cord-347000-zxytdb0b	259	16	and	and	CC
cord-347000-zxytdb0b	259	17	drinking	drinking	NN
cord-347000-zxytdb0b	259	18	water	water	NN
cord-347000-zxytdb0b	259	19	.	.	.
cord-347000-zxytdb0b	260	1	CF	CF	NNP
cord-347000-zxytdb0b	260	2	patients	patient	NNS
cord-347000-zxytdb0b	260	3	are	be	VBP
cord-347000-zxytdb0b	260	4	therefore	therefore	RB
cord-347000-zxytdb0b	260	5	repeatedly	repeatedly	RB
cord-347000-zxytdb0b	260	6	exposed	expose	VBN
cord-347000-zxytdb0b	260	7	to	to	IN
cord-347000-zxytdb0b	260	8	NTM	NTM	NNP
cord-347000-zxytdb0b	260	9	and	and	CC
cord-347000-zxytdb0b	260	10	it	-PRON-	PRP
cord-347000-zxytdb0b	260	11	is	be	VBZ
cord-347000-zxytdb0b	260	12	not	not	RB
cord-347000-zxytdb0b	260	13	surprising	surprising	JJ
cord-347000-zxytdb0b	260	14	that	that	IN
cord-347000-zxytdb0b	260	15	their	-PRON-	PRP$
cord-347000-zxytdb0b	260	16	sputum	sputum	NN
cord-347000-zxytdb0b	260	17	can	can	MD
cord-347000-zxytdb0b	260	18	be	be	VB
cord-347000-zxytdb0b	260	19	infected	infect	VBN
cord-347000-zxytdb0b	260	20	.	.	.
cord-347000-zxytdb0b	261	1	Infection	infection	NN
cord-347000-zxytdb0b	261	2	in	in	IN
cord-347000-zxytdb0b	261	3	CF	CF	NNP
cord-347000-zxytdb0b	261	4	is	be	VBZ
cord-347000-zxytdb0b	261	5	restricted	restrict	VBN
cord-347000-zxytdb0b	261	6	to	to	IN
cord-347000-zxytdb0b	261	7	the	the	DT
cord-347000-zxytdb0b	261	8	lungs	lung	NNS
cord-347000-zxytdb0b	261	9	without	without	IN
cord-347000-zxytdb0b	261	10	the	the	DT
cord-347000-zxytdb0b	261	11	disseminated	disseminate	VBN
cord-347000-zxytdb0b	261	12	NTM	NTM	NNP
cord-347000-zxytdb0b	261	13	disease	disease	NN
cord-347000-zxytdb0b	261	14	found	find	VBN
cord-347000-zxytdb0b	261	15	in	in	IN
cord-347000-zxytdb0b	261	16	patients	patient	NNS
cord-347000-zxytdb0b	261	17	with	with	IN
cord-347000-zxytdb0b	261	18	AIDS	AIDS	NNP
cord-347000-zxytdb0b	261	19	.	.	.
cord-347000-zxytdb0b	262	1	In	in	IN
cord-347000-zxytdb0b	262	2	a	a	DT
cord-347000-zxytdb0b	262	3	study	study	NN
cord-347000-zxytdb0b	262	4	of	of	IN
cord-347000-zxytdb0b	262	5	21	21	CD
cord-347000-zxytdb0b	262	6	USA	USA	NNP
cord-347000-zxytdb0b	262	7	CF	CF	NNP
cord-347000-zxytdb0b	262	8	centres	centre	NNS
cord-347000-zxytdb0b	262	9	,	,	,
cord-347000-zxytdb0b	262	10	128	128	CD
cord-347000-zxytdb0b	262	11	(	(	-LRB-
cord-347000-zxytdb0b	262	12	13	13	CD
cord-347000-zxytdb0b	262	13	%	%	NN
cord-347000-zxytdb0b	262	14	)	)	-RRB-
cord-347000-zxytdb0b	262	15	of	of	IN
cord-347000-zxytdb0b	262	16	986	986	CD
cord-347000-zxytdb0b	262	17	CF	CF	NNP
cord-347000-zxytdb0b	262	18	patients	patient	NNS
cord-347000-zxytdb0b	262	19	over	over	IN
cord-347000-zxytdb0b	262	20	10	10	CD
cord-347000-zxytdb0b	262	21	years	year	NNS
cord-347000-zxytdb0b	262	22	old	old	JJ
cord-347000-zxytdb0b	262	23	had	have	VBD
cord-347000-zxytdb0b	262	24	NTM	NTM	NNP
cord-347000-zxytdb0b	262	25	cultured	culture	VBN
cord-347000-zxytdb0b	262	26	from	from	IN
cord-347000-zxytdb0b	262	27	at	at	RB
cord-347000-zxytdb0b	262	28	least	least	RBS
cord-347000-zxytdb0b	262	29	one	one	CD
cord-347000-zxytdb0b	262	30	of	of	IN
cord-347000-zxytdb0b	262	31	three	three	CD
cord-347000-zxytdb0b	262	32	sputa	sputa	NN
cord-347000-zxytdb0b	262	33	over	over	IN
cord-347000-zxytdb0b	262	34	12	12	CD
cord-347000-zxytdb0b	262	35	months	month	NNS
cord-347000-zxytdb0b	262	36	.	.	.
cord-347000-zxytdb0b	263	1	52	52	CD
cord-347000-zxytdb0b	263	2	Of	of	IN
cord-347000-zxytdb0b	263	3	these	these	DT
cord-347000-zxytdb0b	263	4	25	25	CD
cord-347000-zxytdb0b	263	5	(	(	-LRB-
cord-347000-zxytdb0b	263	6	2.5	2.5	CD
cord-347000-zxytdb0b	263	7	%	%	NN
cord-347000-zxytdb0b	263	8	)	)	-RRB-
cord-347000-zxytdb0b	263	9	met	meet	VBD
cord-347000-zxytdb0b	263	10	the	the	DT
cord-347000-zxytdb0b	263	11	ATS	ATS	NNP
cord-347000-zxytdb0b	263	12	criteria	criterion	NNS
cord-347000-zxytdb0b	263	13	for	for	IN
cord-347000-zxytdb0b	263	14	NTM	NTM	NNP
cord-347000-zxytdb0b	263	15	disease	disease	NN
cord-347000-zxytdb0b	263	16	,	,	,
cord-347000-zxytdb0b	263	17	although	although	IN
cord-347000-zxytdb0b	263	18	the	the	DT
cord-347000-zxytdb0b	263	19	relevance	relevance	NN
cord-347000-zxytdb0b	263	20	of	of	IN
cord-347000-zxytdb0b	263	21	these	these	DT
cord-347000-zxytdb0b	263	22	criteria	criterion	NNS
cord-347000-zxytdb0b	263	23	for	for	IN
cord-347000-zxytdb0b	263	24	patients	patient	NNS
cord-347000-zxytdb0b	263	25	with	with	IN
cord-347000-zxytdb0b	263	26	CF	CF	NNP
cord-347000-zxytdb0b	263	27	has	have	VBZ
cord-347000-zxytdb0b	263	28	not	not	RB
cord-347000-zxytdb0b	263	29	been	be	VBN
cord-347000-zxytdb0b	263	30	assessed	assess	VBN
cord-347000-zxytdb0b	263	31	.	.	.
cord-347000-zxytdb0b	264	1	Infection	infection	NN
cord-347000-zxytdb0b	264	2	with	with	IN
cord-347000-zxytdb0b	264	3	NTM	NTM	NNP
cord-347000-zxytdb0b	264	4	was	be	VBD
cord-347000-zxytdb0b	264	5	more	more	RBR
cord-347000-zxytdb0b	264	6	common	common	JJ
cord-347000-zxytdb0b	264	7	in	in	IN
cord-347000-zxytdb0b	264	8	older	old	JJR
cord-347000-zxytdb0b	264	9	patients	patient	NNS
cord-347000-zxytdb0b	264	10	and	and	CC
cord-347000-zxytdb0b	264	11	was	be	VBD
cord-347000-zxytdb0b	264	12	associated	associate	VBN
cord-347000-zxytdb0b	264	13	with	with	IN
cord-347000-zxytdb0b	264	14	better	well	JJR
cord-347000-zxytdb0b	264	15	lung	lung	NN
cord-347000-zxytdb0b	264	16	function	function	NN
cord-347000-zxytdb0b	264	17	and	and	CC
cord-347000-zxytdb0b	264	18	co	co	NN
cord-347000-zxytdb0b	264	19	-	-	NN
cord-347000-zxytdb0b	264	20	infection	infection	NN
cord-347000-zxytdb0b	264	21	with	with	IN
cord-347000-zxytdb0b	264	22	S.	S.	NNP
cord-347000-zxytdb0b	264	23	aureus	aureus	NN
cord-347000-zxytdb0b	264	24	rather	rather	RB
cord-347000-zxytdb0b	264	25	than	than	IN
cord-347000-zxytdb0b	264	26	P.	P.	NNP
cord-347000-zxytdb0b	264	27	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	264	28	.	.	.
cord-347000-zxytdb0b	265	1	There	there	EX
cord-347000-zxytdb0b	265	2	appears	appear	VBZ
cord-347000-zxytdb0b	265	3	to	to	TO
cord-347000-zxytdb0b	265	4	be	be	VB
cord-347000-zxytdb0b	265	5	a	a	DT
cord-347000-zxytdb0b	265	6	geographical	geographical	JJ
cord-347000-zxytdb0b	265	7	influence	influence	NN
cord-347000-zxytdb0b	265	8	on	on	IN
cord-347000-zxytdb0b	265	9	the	the	DT
cord-347000-zxytdb0b	265	10	overall	overall	JJ
cord-347000-zxytdb0b	265	11	prevalence	prevalence	NN
cord-347000-zxytdb0b	265	12	;	;	:
cord-347000-zxytdb0b	265	13	this	this	DT
cord-347000-zxytdb0b	265	14	ranged	range	VBD
cord-347000-zxytdb0b	265	15	from	from	IN
cord-347000-zxytdb0b	265	16	24	24	CD
cord-347000-zxytdb0b	265	17	%	%	NN
cord-347000-zxytdb0b	265	18	in	in	IN
cord-347000-zxytdb0b	265	19	New	New	NNP
cord-347000-zxytdb0b	265	20	Orleans	Orleans	NNP
cord-347000-zxytdb0b	265	21	to	to	IN
cord-347000-zxytdb0b	265	22	7	7	CD
cord-347000-zxytdb0b	265	23	%	%	NN
cord-347000-zxytdb0b	265	24	in	in	IN
cord-347000-zxytdb0b	265	25	Boston	Boston	NNP
cord-347000-zxytdb0b	265	26	.	.	.
cord-347000-zxytdb0b	266	1	It	-PRON-	PRP
cord-347000-zxytdb0b	266	2	is	be	VBZ
cord-347000-zxytdb0b	266	3	uncertain	uncertain	JJ
cord-347000-zxytdb0b	266	4	however	however	RB
cord-347000-zxytdb0b	266	5	whether	whether	IN
cord-347000-zxytdb0b	266	6	these	these	DT
cord-347000-zxytdb0b	266	7	differences	difference	NNS
cord-347000-zxytdb0b	266	8	relate	relate	VBP
cord-347000-zxytdb0b	266	9	to	to	IN
cord-347000-zxytdb0b	266	10	different	different	JJ
cord-347000-zxytdb0b	266	11	climate	climate	NN
cord-347000-zxytdb0b	266	12	or	or	CC
cord-347000-zxytdb0b	266	13	vegetation	vegetation	NN
cord-347000-zxytdb0b	266	14	or	or	CC
cord-347000-zxytdb0b	266	15	reflect	reflect	VB
cord-347000-zxytdb0b	266	16	the	the	DT
cord-347000-zxytdb0b	266	17	antibiotic	antibiotic	JJ
cord-347000-zxytdb0b	266	18	and	and	CC
cord-347000-zxytdb0b	266	19	steroid	steroid	NN
cord-347000-zxytdb0b	266	20	usage	usage	NN
cord-347000-zxytdb0b	266	21	in	in	IN
cord-347000-zxytdb0b	266	22	those	those	DT
cord-347000-zxytdb0b	266	23	CF	CF	NNP
cord-347000-zxytdb0b	266	24	clinics	clinic	NNS
cord-347000-zxytdb0b	266	25	.	.	.
cord-347000-zxytdb0b	267	1	Members	member	NNS
cord-347000-zxytdb0b	267	2	of	of	IN
cord-347000-zxytdb0b	267	3	the	the	DT
cord-347000-zxytdb0b	267	4	Mycobacterium	Mycobacterium	NNP
cord-347000-zxytdb0b	267	5	avium	avium	NN
cord-347000-zxytdb0b	267	6	complex	complex	NN
cord-347000-zxytdb0b	267	7	were	be	VBD
cord-347000-zxytdb0b	267	8	most	most	RBS
cord-347000-zxytdb0b	267	9	frequently	frequently	RB
cord-347000-zxytdb0b	267	10	isolated	isolate	VBN
cord-347000-zxytdb0b	267	11	(	(	-LRB-
cord-347000-zxytdb0b	267	12	72	72	CD
cord-347000-zxytdb0b	267	13	%	%	NN
cord-347000-zxytdb0b	267	14	of	of	IN
cord-347000-zxytdb0b	267	15	patients	patient	NNS
cord-347000-zxytdb0b	267	16	)	)	-RRB-
cord-347000-zxytdb0b	267	17	,	,	,
cord-347000-zxytdb0b	267	18	with	with	IN
cord-347000-zxytdb0b	267	19	M.	M.	NNP
cord-347000-zxytdb0b	267	20	avium	avium	NN
cord-347000-zxytdb0b	267	21	,	,	,
cord-347000-zxytdb0b	267	22	the	the	DT
cord-347000-zxytdb0b	267	23	predominant	predominant	JJ
cord-347000-zxytdb0b	267	24	species	specie	NNS
cord-347000-zxytdb0b	267	25	.	.	.
cord-347000-zxytdb0b	268	1	Almost	almost	RB
cord-347000-zxytdb0b	268	2	all	all	DT
cord-347000-zxytdb0b	268	3	patients	patient	NNS
cord-347000-zxytdb0b	268	4	had	have	VBD
cord-347000-zxytdb0b	268	5	unique	unique	JJ
cord-347000-zxytdb0b	268	6	strains	strain	NNS
cord-347000-zxytdb0b	268	7	with	with	IN
cord-347000-zxytdb0b	268	8	no	no	DT
cord-347000-zxytdb0b	268	9	evidence	evidence	NN
cord-347000-zxytdb0b	268	10	of	of	IN
cord-347000-zxytdb0b	268	11	cross	cross	NN
cord-347000-zxytdb0b	268	12	-	-	NN
cord-347000-zxytdb0b	268	13	infection	infection	NN
cord-347000-zxytdb0b	268	14	and	and	CC
cord-347000-zxytdb0b	268	15	10	10	CD
cord-347000-zxytdb0b	268	16	%	%	NN
cord-347000-zxytdb0b	268	17	had	have	VBD
cord-347000-zxytdb0b	268	18	mixed	mix	VBN
cord-347000-zxytdb0b	268	19	species	specie	NNS
cord-347000-zxytdb0b	268	20	.	.	.
cord-347000-zxytdb0b	269	1	Mycobacterium	mycobacterium	NN
cord-347000-zxytdb0b	269	2	abscessus	abscessus	NN
cord-347000-zxytdb0b	269	3	only	only	RB
cord-347000-zxytdb0b	269	4	accounted	account	VBD
cord-347000-zxytdb0b	269	5	for	for	IN
cord-347000-zxytdb0b	269	6	16	16	CD
cord-347000-zxytdb0b	269	7	%	%	NN
cord-347000-zxytdb0b	269	8	of	of	IN
cord-347000-zxytdb0b	269	9	NTM	NTM	NNP
cord-347000-zxytdb0b	269	10	cultured	culture	VBN
cord-347000-zxytdb0b	269	11	in	in	IN
cord-347000-zxytdb0b	269	12	the	the	DT
cord-347000-zxytdb0b	269	13	US	US	NNP
cord-347000-zxytdb0b	269	14	study	study	NN
cord-347000-zxytdb0b	269	15	but	but	CC
cord-347000-zxytdb0b	269	16	has	have	VBZ
cord-347000-zxytdb0b	269	17	been	be	VBN
cord-347000-zxytdb0b	269	18	increasingly	increasingly	RB
cord-347000-zxytdb0b	269	19	reported	report	VBN
cord-347000-zxytdb0b	269	20	in	in	IN
cord-347000-zxytdb0b	269	21	CF	CF	NNP
cord-347000-zxytdb0b	269	22	patients	patient	NNS
cord-347000-zxytdb0b	269	23	in	in	IN
cord-347000-zxytdb0b	269	24	Europe	Europe	NNP
cord-347000-zxytdb0b	269	25	.	.	.
cord-347000-zxytdb0b	270	1	53	53	CD
cord-347000-zxytdb0b	271	1	This	this	DT
cord-347000-zxytdb0b	271	2	seems	seem	VBZ
cord-347000-zxytdb0b	271	3	to	to	TO
cord-347000-zxytdb0b	271	4	be	be	VB
cord-347000-zxytdb0b	271	5	associated	associate	VBN
cord-347000-zxytdb0b	271	6	with	with	IN
cord-347000-zxytdb0b	271	7	a	a	DT
cord-347000-zxytdb0b	271	8	more	more	RBR
cord-347000-zxytdb0b	271	9	severe	severe	JJ
cord-347000-zxytdb0b	271	10	infection	infection	NN
cord-347000-zxytdb0b	271	11	,	,	,
cord-347000-zxytdb0b	271	12	and	and	CC
cord-347000-zxytdb0b	271	13	research	research	NN
cord-347000-zxytdb0b	271	14	on	on	IN
cord-347000-zxytdb0b	271	15	pathogenicity	pathogenicity	NN
cord-347000-zxytdb0b	271	16	is	be	VBZ
cord-347000-zxytdb0b	271	17	needed	need	VBN
cord-347000-zxytdb0b	271	18	.	.	.
cord-347000-zxytdb0b	272	1	M.	M.	NNP
cord-347000-zxytdb0b	272	2	abscessus	abscessus	NNP
cord-347000-zxytdb0b	272	3	colonies	colony	NNS
cord-347000-zxytdb0b	272	4	can	can	MD
cord-347000-zxytdb0b	272	5	either	either	CC
cord-347000-zxytdb0b	272	6	be	be	VB
cord-347000-zxytdb0b	272	7	rough	rough	JJ
cord-347000-zxytdb0b	272	8	or	or	CC
cord-347000-zxytdb0b	272	9	smooth	smooth	JJ
cord-347000-zxytdb0b	272	10	depending	depending	NN
cord-347000-zxytdb0b	272	11	on	on	IN
cord-347000-zxytdb0b	272	12	the	the	DT
cord-347000-zxytdb0b	272	13	expression	expression	NN
cord-347000-zxytdb0b	272	14	of	of	IN
cord-347000-zxytdb0b	272	15	glycopeptidolipid	glycopeptidolipid	NNP
cord-347000-zxytdb0b	272	16	(	(	-LRB-
cord-347000-zxytdb0b	272	17	GPL	GPL	NNP
cord-347000-zxytdb0b	272	18	)	)	-RRB-
cord-347000-zxytdb0b	272	19	.	.	.
cord-347000-zxytdb0b	273	1	It	-PRON-	PRP
cord-347000-zxytdb0b	273	2	has	have	VBZ
cord-347000-zxytdb0b	273	3	been	be	VBN
cord-347000-zxytdb0b	273	4	proposed	propose	VBN
cord-347000-zxytdb0b	273	5	that	that	IN
cord-347000-zxytdb0b	273	6	the	the	DT
cord-347000-zxytdb0b	273	7	smooth	smooth	JJ
cord-347000-zxytdb0b	273	8	form	form	NN
cord-347000-zxytdb0b	273	9	(	(	-LRB-
cord-347000-zxytdb0b	273	10	with	with	IN
cord-347000-zxytdb0b	273	11	GPL	GPL	NNP
cord-347000-zxytdb0b	273	12	)	)	-RRB-
cord-347000-zxytdb0b	273	13	forms	form	NNS
cord-347000-zxytdb0b	273	14	biofilms	biofilm	NNS
cord-347000-zxytdb0b	273	15	in	in	IN
cord-347000-zxytdb0b	273	16	vitro	vitro	FW
cord-347000-zxytdb0b	273	17	and	and	CC
cord-347000-zxytdb0b	273	18	is	be	VBZ
cord-347000-zxytdb0b	273	19	less	less	RBR
cord-347000-zxytdb0b	273	20	pathogenic	pathogenic	RB
cord-347000-zxytdb0b	273	21	-	-	HYPH
cord-347000-zxytdb0b	273	22	favouring	favour	VBG
cord-347000-zxytdb0b	273	23	colonization	colonization	NN
cord-347000-zxytdb0b	273	24	whereas	whereas	IN
cord-347000-zxytdb0b	273	25	the	the	DT
cord-347000-zxytdb0b	273	26	rough	rough	JJ
cord-347000-zxytdb0b	273	27	form	form	NN
cord-347000-zxytdb0b	273	28	produces	produce	VBZ
cord-347000-zxytdb0b	273	29	little	little	JJ
cord-347000-zxytdb0b	273	30	GPL	GPL	NNP
cord-347000-zxytdb0b	273	31	,	,	,
cord-347000-zxytdb0b	273	32	infects	infect	VBZ
cord-347000-zxytdb0b	273	33	human	human	JJ
cord-347000-zxytdb0b	273	34	monocytes	monocyte	NNS
cord-347000-zxytdb0b	273	35	and	and	CC
cord-347000-zxytdb0b	273	36	causes	cause	VBZ
cord-347000-zxytdb0b	273	37	persistent	persistent	JJ
cord-347000-zxytdb0b	273	38	invasive	invasive	JJ
cord-347000-zxytdb0b	273	39	infection	infection	NN
cord-347000-zxytdb0b	273	40	in	in	IN
cord-347000-zxytdb0b	273	41	a	a	DT
cord-347000-zxytdb0b	273	42	mouse	mouse	NN
cord-347000-zxytdb0b	273	43	model	model	NN
cord-347000-zxytdb0b	273	44	.	.	.
cord-347000-zxytdb0b	274	1	54	54	CD
cord-347000-zxytdb0b	275	1	,	,	,
cord-347000-zxytdb0b	275	2	55	55	CD
cord-347000-zxytdb0b	276	1	A	a	DT
cord-347000-zxytdb0b	276	2	similar	similar	JJ
cord-347000-zxytdb0b	276	3	relationship	relationship	NN
cord-347000-zxytdb0b	276	4	between	between	IN
cord-347000-zxytdb0b	276	5	colonial	colonial	JJ
cord-347000-zxytdb0b	276	6	morphology	morphology	NN
cord-347000-zxytdb0b	276	7	and	and	CC
cord-347000-zxytdb0b	276	8	virulence	virulence	NN
cord-347000-zxytdb0b	276	9	has	have	VBZ
cord-347000-zxytdb0b	276	10	been	be	VBN
cord-347000-zxytdb0b	276	11	proposed	propose	VBN
cord-347000-zxytdb0b	276	12	for	for	IN
cord-347000-zxytdb0b	276	13	M.	M.	NNP
cord-347000-zxytdb0b	276	14	avium	avium	NN
cord-347000-zxytdb0b	276	15	and	and	CC
cord-347000-zxytdb0b	276	16	M.	M.	NNP
cord-347000-zxytdb0b	276	17	kansasii	kansasii	NNS
cord-347000-zxytdb0b	276	18	.	.	.
cord-347000-zxytdb0b	277	1	There	there	EX
cord-347000-zxytdb0b	277	2	have	have	VBP
cord-347000-zxytdb0b	277	3	however	however	RB
cord-347000-zxytdb0b	277	4	been	be	VBN
cord-347000-zxytdb0b	277	5	no	no	DT
cord-347000-zxytdb0b	277	6	studies	study	NNS
cord-347000-zxytdb0b	277	7	to	to	TO
cord-347000-zxytdb0b	277	8	test	test	VB
cord-347000-zxytdb0b	277	9	the	the	DT
cord-347000-zxytdb0b	277	10	clinical	clinical	JJ
cord-347000-zxytdb0b	277	11	relevance	relevance	NN
cord-347000-zxytdb0b	277	12	of	of	IN
cord-347000-zxytdb0b	277	13	these	these	DT
cord-347000-zxytdb0b	277	14	observations	observation	NNS
cord-347000-zxytdb0b	277	15	.	.	.
cord-347000-zxytdb0b	278	1	In	in	IN
cord-347000-zxytdb0b	278	2	common	common	JJ
cord-347000-zxytdb0b	278	3	with	with	IN
cord-347000-zxytdb0b	278	4	other	other	JJ
cord-347000-zxytdb0b	278	5	bacteria	bacteria	NNS
cord-347000-zxytdb0b	278	6	that	that	WDT
cord-347000-zxytdb0b	278	7	may	may	MD
cord-347000-zxytdb0b	278	8	persist	persist	VB
cord-347000-zxytdb0b	278	9	in	in	IN
cord-347000-zxytdb0b	278	10	biofilms	biofilm	NNS
cord-347000-zxytdb0b	278	11	,	,	,
cord-347000-zxytdb0b	278	12	M.	M.	NNP
cord-347000-zxytdb0b	278	13	abscessus	abscessus	NN
cord-347000-zxytdb0b	278	14	appears	appear	VBZ
cord-347000-zxytdb0b	278	15	less	less	RBR
cord-347000-zxytdb0b	278	16	susceptible	susceptible	JJ
cord-347000-zxytdb0b	278	17	to	to	IN
cord-347000-zxytdb0b	278	18	antibiotics	antibiotic	NNS
cord-347000-zxytdb0b	278	19	when	when	WRB
cord-347000-zxytdb0b	278	20	grown	grow	VBN
cord-347000-zxytdb0b	278	21	in	in	IN
cord-347000-zxytdb0b	278	22	biofilms	biofilm	NNS
cord-347000-zxytdb0b	278	23	than	than	IN
cord-347000-zxytdb0b	278	24	in	in	IN
cord-347000-zxytdb0b	278	25	planktonic	planktonic	JJ
cord-347000-zxytdb0b	278	26	cultures	culture	NNS
cord-347000-zxytdb0b	278	27	.	.	.
cord-347000-zxytdb0b	279	1	56	56	CD
cord-347000-zxytdb0b	280	1	The	the	DT
cord-347000-zxytdb0b	280	2	clinical	clinical	JJ
cord-347000-zxytdb0b	280	3	relevance	relevance	NN
cord-347000-zxytdb0b	280	4	of	of	IN
cord-347000-zxytdb0b	280	5	NTM	NTM	NNP
cord-347000-zxytdb0b	280	6	can	can	MD
cord-347000-zxytdb0b	280	7	be	be	VB
cord-347000-zxytdb0b	280	8	difficult	difficult	JJ
cord-347000-zxytdb0b	280	9	to	to	TO
cord-347000-zxytdb0b	280	10	assess	assess	VB
cord-347000-zxytdb0b	280	11	in	in	IN
cord-347000-zxytdb0b	280	12	CF	CF	NNP
cord-347000-zxytdb0b	280	13	as	as	IN
cord-347000-zxytdb0b	280	14	these	these	DT
cord-347000-zxytdb0b	280	15	patients	patient	NNS
cord-347000-zxytdb0b	280	16	usually	usually	RB
cord-347000-zxytdb0b	280	17	have	have	VBP
cord-347000-zxytdb0b	280	18	other	other	JJ
cord-347000-zxytdb0b	280	19	pathogens	pathogen	NNS
cord-347000-zxytdb0b	280	20	in	in	IN
cord-347000-zxytdb0b	280	21	their	-PRON-	PRP$
cord-347000-zxytdb0b	280	22	sputum	sputum	NN
cord-347000-zxytdb0b	280	23	.	.	.
cord-347000-zxytdb0b	281	1	In	in	IN
cord-347000-zxytdb0b	281	2	addition	addition	NN
cord-347000-zxytdb0b	281	3	,	,	,
cord-347000-zxytdb0b	281	4	NTM	NTM	NNP
cord-347000-zxytdb0b	281	5	of	of	IN
cord-347000-zxytdb0b	281	6	different	different	JJ
cord-347000-zxytdb0b	281	7	species	specie	NNS
cord-347000-zxytdb0b	281	8	may	may	MD
cord-347000-zxytdb0b	281	9	be	be	VB
cord-347000-zxytdb0b	281	10	cultured	culture	VBN
cord-347000-zxytdb0b	281	11	on	on	IN
cord-347000-zxytdb0b	281	12	different	different	JJ
cord-347000-zxytdb0b	281	13	occasions	occasion	NNS
cord-347000-zxytdb0b	281	14	such	such	JJ
cord-347000-zxytdb0b	281	15	that	that	IN
cord-347000-zxytdb0b	281	16	it	-PRON-	PRP
cord-347000-zxytdb0b	281	17	can	can	MD
cord-347000-zxytdb0b	281	18	be	be	VB
cord-347000-zxytdb0b	281	19	difficult	difficult	JJ
cord-347000-zxytdb0b	281	20	to	to	TO
cord-347000-zxytdb0b	281	21	distinguish	distinguish	VB
cord-347000-zxytdb0b	281	22	repeated	repeat	VBN
cord-347000-zxytdb0b	281	23	acquisition	acquisition	NN
cord-347000-zxytdb0b	281	24	and	and	CC
cord-347000-zxytdb0b	281	25	loss	loss	NN
cord-347000-zxytdb0b	281	26	from	from	IN
cord-347000-zxytdb0b	281	27	the	the	DT
cord-347000-zxytdb0b	281	28	environment	environment	NN
cord-347000-zxytdb0b	281	29	from	from	IN
cord-347000-zxytdb0b	281	30	established	establish	VBN
cord-347000-zxytdb0b	281	31	infection	infection	NN
cord-347000-zxytdb0b	281	32	.	.	.
cord-347000-zxytdb0b	282	1	All	all	DT
cord-347000-zxytdb0b	282	2	isolates	isolate	NNS
cord-347000-zxytdb0b	282	3	therefore	therefore	RB
cord-347000-zxytdb0b	282	4	need	need	VBP
cord-347000-zxytdb0b	282	5	to	to	TO
cord-347000-zxytdb0b	282	6	be	be	VB
cord-347000-zxytdb0b	282	7	identified	identify	VBN
cord-347000-zxytdb0b	282	8	rather	rather	RB
cord-347000-zxytdb0b	282	9	than	than	IN
cord-347000-zxytdb0b	282	10	assuming	assume	VBG
cord-347000-zxytdb0b	282	11	that	that	DT
cord-347000-zxytdb0b	282	12	repeat	repeat	VB
cord-347000-zxytdb0b	282	13	positive	positive	JJ
cord-347000-zxytdb0b	282	14	cultures	culture	NNS
cord-347000-zxytdb0b	282	15	of	of	IN
cord-347000-zxytdb0b	282	16	Mycobacterium	Mycobacterium	NNP
cord-347000-zxytdb0b	282	17	spp	spp	NNS
cord-347000-zxytdb0b	282	18	.	.	.
cord-347000-zxytdb0b	283	1	indicate	indicate	VBP
cord-347000-zxytdb0b	283	2	persistent	persistent	JJ
cord-347000-zxytdb0b	283	3	infection	infection	NN
cord-347000-zxytdb0b	283	4	.	.	.
cord-347000-zxytdb0b	284	1	Difficulties	difficulty	NNS
cord-347000-zxytdb0b	284	2	with	with	IN
cord-347000-zxytdb0b	284	3	identification	identification	NN
cord-347000-zxytdb0b	284	4	and	and	CC
cord-347000-zxytdb0b	284	5	changes	change	NNS
cord-347000-zxytdb0b	284	6	in	in	IN
cord-347000-zxytdb0b	284	7	taxonomy	taxonomy	NN
cord-347000-zxytdb0b	284	8	mean	mean	VB
cord-347000-zxytdb0b	284	9	that	that	IN
cord-347000-zxytdb0b	284	10	previous	previous	JJ
cord-347000-zxytdb0b	284	11	infection	infection	NN
cord-347000-zxytdb0b	284	12	attributed	attribute	VBN
cord-347000-zxytdb0b	284	13	to	to	IN
cord-347000-zxytdb0b	284	14	M.	M.	NNP
cord-347000-zxytdb0b	284	15	fortuitum	fortuitum	JJ
cord-347000-zxytdb0b	284	16	complex	complex	NN
cord-347000-zxytdb0b	284	17	or	or	CC
cord-347000-zxytdb0b	284	18	with	with	IN
cord-347000-zxytdb0b	284	19	M.	M.	NNP
cord-347000-zxytdb0b	284	20	chelonae	chelonae	NNP
cord-347000-zxytdb0b	284	21	may	may	MD
cord-347000-zxytdb0b	284	22	have	have	VB
cord-347000-zxytdb0b	284	23	been	be	VBN
cord-347000-zxytdb0b	284	24	due	due	JJ
cord-347000-zxytdb0b	284	25	to	to	IN
cord-347000-zxytdb0b	284	26	M.	M.	NNP
cord-347000-zxytdb0b	284	27	abscessus	abscessu	NNS
cord-347000-zxytdb0b	284	28	.	.	.
cord-347000-zxytdb0b	285	1	The	the	DT
cord-347000-zxytdb0b	285	2	role	role	NN
cord-347000-zxytdb0b	285	3	of	of	IN
cord-347000-zxytdb0b	285	4	in	in	FW
cord-347000-zxytdb0b	285	5	vitro	vitro	FW
cord-347000-zxytdb0b	285	6	susceptibility	susceptibility	NN
cord-347000-zxytdb0b	285	7	testing	testing	NN
cord-347000-zxytdb0b	285	8	of	of	IN
cord-347000-zxytdb0b	285	9	M.	M.	NNP
cord-347000-zxytdb0b	285	10	abscessus	abscessus	NN
cord-347000-zxytdb0b	285	11	is	be	VBZ
cord-347000-zxytdb0b	285	12	in	in	IN
cord-347000-zxytdb0b	285	13	question	question	NN
cord-347000-zxytdb0b	285	14	as	as	IN
cord-347000-zxytdb0b	285	15	correlation	correlation	NN
cord-347000-zxytdb0b	285	16	with	with	IN
cord-347000-zxytdb0b	285	17	clinical	clinical	JJ
cord-347000-zxytdb0b	285	18	response	response	NN
cord-347000-zxytdb0b	285	19	is	be	VBZ
cord-347000-zxytdb0b	285	20	poor	poor	JJ
cord-347000-zxytdb0b	285	21	.	.	.
cord-347000-zxytdb0b	286	1	Only	only	RB
cord-347000-zxytdb0b	286	2	susceptibility	susceptibility	NN
cord-347000-zxytdb0b	286	3	testing	testing	NN
cord-347000-zxytdb0b	286	4	to	to	IN
cord-347000-zxytdb0b	286	5	the	the	DT
cord-347000-zxytdb0b	286	6	macrolides	macrolide	NNS
cord-347000-zxytdb0b	286	7	(	(	-LRB-
cord-347000-zxytdb0b	286	8	clarithromycin	clarithromycin	NNS
cord-347000-zxytdb0b	286	9	,	,	,
cord-347000-zxytdb0b	286	10	azithromycin	azithromycin	NNP
cord-347000-zxytdb0b	286	11	)	)	-RRB-
cord-347000-zxytdb0b	286	12	is	be	VBZ
cord-347000-zxytdb0b	286	13	recommended	recommend	VBN
cord-347000-zxytdb0b	286	14	for	for	IN
cord-347000-zxytdb0b	286	15	M.	M.	NNP
cord-347000-zxytdb0b	286	16	avium	avium	NN
cord-347000-zxytdb0b	286	17	complex	complex	NN
cord-347000-zxytdb0b	286	18	.	.	.
cord-347000-zxytdb0b	287	1	57	57	CD
cord-347000-zxytdb0b	287	2	Areas	area	NNS
cord-347000-zxytdb0b	287	3	that	that	WDT
cord-347000-zxytdb0b	287	4	need	need	VBP
cord-347000-zxytdb0b	287	5	more	more	JJR
cord-347000-zxytdb0b	287	6	work	work	NN
cord-347000-zxytdb0b	287	7	include	include	VBP
cord-347000-zxytdb0b	287	8	reliable	reliable	JJ
cord-347000-zxytdb0b	287	9	culture	culture	NN
cord-347000-zxytdb0b	287	10	and	and	CC
cord-347000-zxytdb0b	287	11	identification	identification	NN
cord-347000-zxytdb0b	287	12	of	of	IN
cord-347000-zxytdb0b	287	13	NTM	NTM	NNP
cord-347000-zxytdb0b	287	14	,	,	,
cord-347000-zxytdb0b	287	15	clinically	clinically	RB
cord-347000-zxytdb0b	287	16	relevant	relevant	JJ
cord-347000-zxytdb0b	287	17	tests	test	NNS
cord-347000-zxytdb0b	287	18	to	to	TO
cord-347000-zxytdb0b	287	19	measure	measure	VB
cord-347000-zxytdb0b	287	20	antibiotic	antibiotic	JJ
cord-347000-zxytdb0b	287	21	susceptibility	susceptibility	NN
cord-347000-zxytdb0b	287	22	and	and	CC
cord-347000-zxytdb0b	287	23	more	more	JJR
cord-347000-zxytdb0b	287	24	understanding	understanding	NN
cord-347000-zxytdb0b	287	25	of	of	IN
cord-347000-zxytdb0b	287	26	pathogenicity	pathogenicity	NN
cord-347000-zxytdb0b	287	27	mechanisms	mechanism	NNS
cord-347000-zxytdb0b	287	28	,	,	,
cord-347000-zxytdb0b	287	29	in	in	IN
cord-347000-zxytdb0b	287	30	particular	particular	JJ
cord-347000-zxytdb0b	287	31	,	,	,
cord-347000-zxytdb0b	287	32	for	for	IN
cord-347000-zxytdb0b	287	33	M.	M.	NNP
cord-347000-zxytdb0b	287	34	abscessus	abscessu	NNS
cord-347000-zxytdb0b	287	35	.	.	.
cord-347000-zxytdb0b	288	1	Building	build	VBG
cord-347000-zxytdb0b	288	2	on	on	IN
cord-347000-zxytdb0b	288	3	the	the	DT
cord-347000-zxytdb0b	288	4	ATS	ATS	NNP
cord-347000-zxytdb0b	288	5	guidelines	guideline	NNS
cord-347000-zxytdb0b	288	6	,	,	,
cord-347000-zxytdb0b	288	7	more	more	RBR
cord-347000-zxytdb0b	288	8	specific	specific	JJ
cord-347000-zxytdb0b	288	9	definitions	definition	NNS
cord-347000-zxytdb0b	288	10	for	for	IN
cord-347000-zxytdb0b	288	11	CF	cf	NN
cord-347000-zxytdb0b	288	12	to	to	TO
cord-347000-zxytdb0b	288	13	distinguish	distinguish	VB
cord-347000-zxytdb0b	288	14	transient	transient	JJ
cord-347000-zxytdb0b	288	15	carriage	carriage	NN
cord-347000-zxytdb0b	288	16	,	,	,
cord-347000-zxytdb0b	288	17	colonization	colonization	NN
cord-347000-zxytdb0b	288	18	and	and	CC
cord-347000-zxytdb0b	288	19	clinical	clinical	JJ
cord-347000-zxytdb0b	288	20	infection	infection	NN
cord-347000-zxytdb0b	288	21	are	be	VBP
cord-347000-zxytdb0b	288	22	needed	need	VBN
cord-347000-zxytdb0b	288	23	for	for	IN
cord-347000-zxytdb0b	288	24	trials	trial	NNS
cord-347000-zxytdb0b	288	25	of	of	IN
cord-347000-zxytdb0b	288	26	treatment	treatment	NN
cord-347000-zxytdb0b	288	27	.	.	.
cord-347000-zxytdb0b	289	1	Various	various	JJ
cord-347000-zxytdb0b	289	2	species	specie	NNS
cord-347000-zxytdb0b	289	3	of	of	IN
cord-347000-zxytdb0b	289	4	Aspergillus	aspergillus	NN
cord-347000-zxytdb0b	289	5	,	,	,
cord-347000-zxytdb0b	289	6	most	most	RBS
cord-347000-zxytdb0b	289	7	commonly	commonly	RB
cord-347000-zxytdb0b	289	8	Aspergillus	aspergillus	NN
cord-347000-zxytdb0b	289	9	fumigatus	fumigatus	NN
cord-347000-zxytdb0b	289	10	,	,	,
cord-347000-zxytdb0b	289	11	can	can	MD
cord-347000-zxytdb0b	289	12	be	be	VB
cord-347000-zxytdb0b	289	13	cultured	culture	VBN
cord-347000-zxytdb0b	289	14	from	from	IN
cord-347000-zxytdb0b	289	15	CF	cf	NN
cord-347000-zxytdb0b	289	16	sputum	sputum	NN
cord-347000-zxytdb0b	289	17	.	.	.
cord-347000-zxytdb0b	290	1	The	the	DT
cord-347000-zxytdb0b	290	2	fungal	fungal	NN
cord-347000-zxytdb0b	290	3	spores	spore	NNS
cord-347000-zxytdb0b	290	4	are	be	VBP
cord-347000-zxytdb0b	290	5	common	common	JJ
cord-347000-zxytdb0b	290	6	in	in	IN
cord-347000-zxytdb0b	290	7	the	the	DT
cord-347000-zxytdb0b	290	8	air	air	NN
cord-347000-zxytdb0b	290	9	and	and	CC
cord-347000-zxytdb0b	290	10	water	water	NN
cord-347000-zxytdb0b	290	11	,	,	,
cord-347000-zxytdb0b	290	12	and	and	CC
cord-347000-zxytdb0b	290	13	are	be	VBP
cord-347000-zxytdb0b	290	14	usually	usually	RB
cord-347000-zxytdb0b	290	15	derived	derive	VBN
cord-347000-zxytdb0b	290	16	from	from	IN
cord-347000-zxytdb0b	290	17	rotting	rot	VBG
cord-347000-zxytdb0b	290	18	vegetation	vegetation	NN
cord-347000-zxytdb0b	290	19	.	.	.
cord-347000-zxytdb0b	291	1	Aspergillus	Aspergillus	NNP
cord-347000-zxytdb0b	291	2	may	may	MD
cord-347000-zxytdb0b	291	3	contaminate	contaminate	VB
cord-347000-zxytdb0b	291	4	sputum	sputum	NN
cord-347000-zxytdb0b	291	5	containers	container	NNS
cord-347000-zxytdb0b	291	6	or	or	CC
cord-347000-zxytdb0b	291	7	even	even	RB
cord-347000-zxytdb0b	291	8	laboratory	laboratory	NN
cord-347000-zxytdb0b	291	9	cultures	culture	NNS
cord-347000-zxytdb0b	291	10	.	.	.
cord-347000-zxytdb0b	292	1	In	in	IN
cord-347000-zxytdb0b	292	2	CF	CF	NNP
cord-347000-zxytdb0b	292	3	,	,	,
cord-347000-zxytdb0b	292	4	it	-PRON-	PRP
cord-347000-zxytdb0b	292	5	can	can	MD
cord-347000-zxytdb0b	292	6	cause	cause	VB
cord-347000-zxytdb0b	292	7	allergic	allergic	JJ
cord-347000-zxytdb0b	292	8	broncho	broncho	JJ
cord-347000-zxytdb0b	292	9	-	-	HYPH
cord-347000-zxytdb0b	292	10	pulmonary	pulmonary	NN
cord-347000-zxytdb0b	292	11	aspergillosis	aspergillosis	NN
cord-347000-zxytdb0b	292	12	(	(	-LRB-
cord-347000-zxytdb0b	292	13	ABPA	ABPA	NNP
cord-347000-zxytdb0b	292	14	)	)	-RRB-
cord-347000-zxytdb0b	292	15	.	.	.
cord-347000-zxytdb0b	293	1	Diagnostic	diagnostic	JJ
cord-347000-zxytdb0b	293	2	criteria	criterion	NNS
cord-347000-zxytdb0b	293	3	for	for	IN
cord-347000-zxytdb0b	293	4	ABPA	ABPA	NNP
cord-347000-zxytdb0b	293	5	in	in	IN
cord-347000-zxytdb0b	293	6	CF	CF	NNP
cord-347000-zxytdb0b	293	7	have	have	VBP
cord-347000-zxytdb0b	293	8	been	be	VBN
cord-347000-zxytdb0b	293	9	published	publish	VBN
cord-347000-zxytdb0b	293	10	58	58	CD
cord-347000-zxytdb0b	293	11	and	and	CC
cord-347000-zxytdb0b	293	12	patients	patient	NNS
cord-347000-zxytdb0b	293	13	are	be	VBP
cord-347000-zxytdb0b	293	14	treated	treat	VBN
cord-347000-zxytdb0b	293	15	with	with	IN
cord-347000-zxytdb0b	293	16	steroids	steroid	NNS
cord-347000-zxytdb0b	293	17	and	and	CC
cord-347000-zxytdb0b	293	18	antifungals	antifungal	NNS
cord-347000-zxytdb0b	293	19	.	.	.
cord-347000-zxytdb0b	294	1	Aspergillomas	aspergilloma	NNS
cord-347000-zxytdb0b	294	2	have	have	VBP
cord-347000-zxytdb0b	294	3	also	also	RB
cord-347000-zxytdb0b	294	4	been	be	VBN
cord-347000-zxytdb0b	294	5	seen	see	VBN
cord-347000-zxytdb0b	294	6	in	in	IN
cord-347000-zxytdb0b	294	7	CF	cf	NN
cord-347000-zxytdb0b	294	8	but	but	CC
cord-347000-zxytdb0b	294	9	are	be	VBP
cord-347000-zxytdb0b	294	10	rare	rare	JJ
cord-347000-zxytdb0b	294	11	.	.	.
cord-347000-zxytdb0b	295	1	A	a	DT
cord-347000-zxytdb0b	295	2	recent	recent	JJ
cord-347000-zxytdb0b	295	3	paper	paper	NN
cord-347000-zxytdb0b	295	4	has	have	VBZ
cord-347000-zxytdb0b	295	5	described	describe	VBN
cord-347000-zxytdb0b	295	6	a	a	DT
cord-347000-zxytdb0b	295	7	bronchitis	bronchitis	NN
cord-347000-zxytdb0b	295	8	in	in	IN
cord-347000-zxytdb0b	295	9	six	six	CD
cord-347000-zxytdb0b	295	10	patients	patient	NNS
cord-347000-zxytdb0b	295	11	with	with	IN
cord-347000-zxytdb0b	295	12	infection	infection	NN
cord-347000-zxytdb0b	295	13	with	with	IN
cord-347000-zxytdb0b	295	14	Aspergillus	aspergillus	NN
cord-347000-zxytdb0b	295	15	without	without	IN
cord-347000-zxytdb0b	295	16	the	the	DT
cord-347000-zxytdb0b	295	17	features	feature	NNS
cord-347000-zxytdb0b	295	18	of	of	IN
cord-347000-zxytdb0b	295	19	ABPA	ABPA	NNS
cord-347000-zxytdb0b	295	20	who	who	WP
cord-347000-zxytdb0b	295	21	responded	respond	VBD
cord-347000-zxytdb0b	295	22	to	to	IN
cord-347000-zxytdb0b	295	23	antifungal	antifungal	NN
cord-347000-zxytdb0b	295	24	therapy	therapy	NN
cord-347000-zxytdb0b	295	25	.	.	.
cord-347000-zxytdb0b	296	1	59	59	CD
cord-347000-zxytdb0b	296	2	Scedosporium	Scedosporium	NNP
cord-347000-zxytdb0b	296	3	apiospermum	apiospermum	NN
cord-347000-zxytdb0b	296	4	has	have	VBZ
cord-347000-zxytdb0b	296	5	also	also	RB
cord-347000-zxytdb0b	296	6	been	be	VBN
cord-347000-zxytdb0b	296	7	associated	associate	VBN
cord-347000-zxytdb0b	296	8	with	with	IN
cord-347000-zxytdb0b	296	9	the	the	DT
cord-347000-zxytdb0b	296	10	ABPA	abpa	NN
cord-347000-zxytdb0b	296	11	-	-	HYPH
cord-347000-zxytdb0b	296	12	like	like	JJ
cord-347000-zxytdb0b	296	13	picture	picture	NN
cord-347000-zxytdb0b	296	14	in	in	IN
cord-347000-zxytdb0b	296	15	CF	CF	NNP
cord-347000-zxytdb0b	296	16	.	.	.
cord-347000-zxytdb0b	297	1	60	60	CD
cord-347000-zxytdb0b	297	2	Candida	Candida	NNP
cord-347000-zxytdb0b	297	3	spp	spp	NNS
cord-347000-zxytdb0b	297	4	.	.	.
cord-347000-zxytdb0b	298	1	are	be	VBP
cord-347000-zxytdb0b	298	2	commonly	commonly	RB
cord-347000-zxytdb0b	298	3	cultured	culture	VBN
cord-347000-zxytdb0b	298	4	from	from	IN
cord-347000-zxytdb0b	298	5	CF	cf	NN
cord-347000-zxytdb0b	298	6	sputum	sputum	NN
cord-347000-zxytdb0b	298	7	.	.	.
cord-347000-zxytdb0b	299	1	This	this	DT
cord-347000-zxytdb0b	299	2	is	be	VBZ
cord-347000-zxytdb0b	299	3	not	not	RB
cord-347000-zxytdb0b	299	4	unexpected	unexpected	JJ
cord-347000-zxytdb0b	299	5	given	give	VBN
cord-347000-zxytdb0b	299	6	that	that	IN
cord-347000-zxytdb0b	299	7	much	much	JJ
cord-347000-zxytdb0b	299	8	antibiotic	antibiotic	JJ
cord-347000-zxytdb0b	299	9	treatment	treatment	NN
cord-347000-zxytdb0b	299	10	in	in	IN
cord-347000-zxytdb0b	299	11	CF	CF	NNP
cord-347000-zxytdb0b	299	12	is	be	VBZ
cord-347000-zxytdb0b	299	13	broad	broad	JJ
cord-347000-zxytdb0b	299	14	spectrum	spectrum	NN
cord-347000-zxytdb0b	299	15	and	and	CC
cord-347000-zxytdb0b	299	16	can	can	MD
cord-347000-zxytdb0b	299	17	lead	lead	VB
cord-347000-zxytdb0b	299	18	to	to	IN
cord-347000-zxytdb0b	299	19	an	an	DT
cord-347000-zxytdb0b	299	20	overgrowth	overgrowth	NN
cord-347000-zxytdb0b	299	21	of	of	IN
cord-347000-zxytdb0b	299	22	Candida	Candida	NNP
cord-347000-zxytdb0b	299	23	spp	spp	NNS
cord-347000-zxytdb0b	299	24	.	.	.
cord-347000-zxytdb0b	300	1	on	on	IN
cord-347000-zxytdb0b	300	2	mucosal	mucosal	JJ
cord-347000-zxytdb0b	300	3	surfaces	surface	NNS
cord-347000-zxytdb0b	300	4	.	.	.
cord-347000-zxytdb0b	301	1	Some	some	DT
cord-347000-zxytdb0b	301	2	cultures	culture	NNS
cord-347000-zxytdb0b	301	3	are	be	VBP
cord-347000-zxytdb0b	301	4	therefore	therefore	RB
cord-347000-zxytdb0b	301	5	due	due	IN
cord-347000-zxytdb0b	301	6	to	to	IN
cord-347000-zxytdb0b	301	7	oral	oral	JJ
cord-347000-zxytdb0b	301	8	contamination	contamination	NN
cord-347000-zxytdb0b	301	9	of	of	IN
cord-347000-zxytdb0b	301	10	sputum	sputum	NN
cord-347000-zxytdb0b	301	11	but	but	CC
cord-347000-zxytdb0b	301	12	colonization	colonization	NN
cord-347000-zxytdb0b	301	13	of	of	IN
cord-347000-zxytdb0b	301	14	sputum	sputum	NN
cord-347000-zxytdb0b	301	15	is	be	VBZ
cord-347000-zxytdb0b	301	16	also	also	RB
cord-347000-zxytdb0b	301	17	possible	possible	JJ
cord-347000-zxytdb0b	301	18	.	.	.
cord-347000-zxytdb0b	302	1	There	there	EX
cord-347000-zxytdb0b	302	2	is	be	VBZ
cord-347000-zxytdb0b	302	3	no	no	DT
cord-347000-zxytdb0b	302	4	current	current	JJ
cord-347000-zxytdb0b	302	5	evidence	evidence	NN
cord-347000-zxytdb0b	302	6	of	of	IN
cord-347000-zxytdb0b	302	7	a	a	DT
cord-347000-zxytdb0b	302	8	significant	significant	JJ
cord-347000-zxytdb0b	302	9	role	role	NN
cord-347000-zxytdb0b	302	10	for	for	IN
cord-347000-zxytdb0b	302	11	Candida	Candida	NNP
cord-347000-zxytdb0b	302	12	spp	spp	NNS
cord-347000-zxytdb0b	302	13	.	.	.
cord-347000-zxytdb0b	303	1	in	in	IN
cord-347000-zxytdb0b	303	2	lower	low	JJR
cord-347000-zxytdb0b	303	3	airway	airway	NN
cord-347000-zxytdb0b	303	4	infection	infection	NN
cord-347000-zxytdb0b	303	5	.	.	.
cord-347000-zxytdb0b	304	1	The	the	DT
cord-347000-zxytdb0b	304	2	possible	possible	JJ
cord-347000-zxytdb0b	304	3	role	role	NN
cord-347000-zxytdb0b	304	4	of	of	IN
cord-347000-zxytdb0b	304	5	normal	normal	JJ
cord-347000-zxytdb0b	304	6	oral	oral	JJ
cord-347000-zxytdb0b	304	7	flora	flora	NNS
cord-347000-zxytdb0b	304	8	in	in	IN
cord-347000-zxytdb0b	304	9	cystic	cystic	JJ
cord-347000-zxytdb0b	304	10	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	304	11	sputum	sputum	NN
cord-347000-zxytdb0b	305	1	Bacteria	Bacteria	NNS
cord-347000-zxytdb0b	305	2	usually	usually	RB
cord-347000-zxytdb0b	305	3	labelled	label	VBN
cord-347000-zxytdb0b	305	4	as	as	IN
cord-347000-zxytdb0b	305	5	normal	normal	JJ
cord-347000-zxytdb0b	305	6	flora	flora	NNS
cord-347000-zxytdb0b	305	7	in	in	IN
cord-347000-zxytdb0b	305	8	the	the	DT
cord-347000-zxytdb0b	305	9	mouth	mouth	NN
cord-347000-zxytdb0b	305	10	and	and	CC
cord-347000-zxytdb0b	305	11	upper	upper	JJ
cord-347000-zxytdb0b	305	12	airways	airway	NNS
cord-347000-zxytdb0b	305	13	are	be	VBP
cord-347000-zxytdb0b	305	14	often	often	RB
cord-347000-zxytdb0b	305	15	grown	grow	VBN
cord-347000-zxytdb0b	305	16	from	from	IN
cord-347000-zxytdb0b	305	17	sputum	sputum	NN
cord-347000-zxytdb0b	305	18	and	and	CC
cord-347000-zxytdb0b	305	19	even	even	RB
cord-347000-zxytdb0b	305	20	from	from	IN
cord-347000-zxytdb0b	305	21	samples	sample	NNS
cord-347000-zxytdb0b	305	22	taken	take	VBN
cord-347000-zxytdb0b	305	23	at	at	IN
cord-347000-zxytdb0b	305	24	bronchoscopy	bronchoscopy	NN
cord-347000-zxytdb0b	305	25	.	.	.
cord-347000-zxytdb0b	306	1	These	these	DT
cord-347000-zxytdb0b	306	2	were	be	VBD
cord-347000-zxytdb0b	306	3	thought	think	VBN
cord-347000-zxytdb0b	306	4	to	to	TO
cord-347000-zxytdb0b	306	5	be	be	VB
cord-347000-zxytdb0b	306	6	due	due	JJ
cord-347000-zxytdb0b	306	7	to	to	IN
cord-347000-zxytdb0b	306	8	contamination	contamination	NN
cord-347000-zxytdb0b	306	9	with	with	IN
cord-347000-zxytdb0b	306	10	saliva	saliva	NN
cord-347000-zxytdb0b	306	11	,	,	,
cord-347000-zxytdb0b	306	12	however	however	RB
cord-347000-zxytdb0b	306	13	these	these	DT
cord-347000-zxytdb0b	306	14	bacteria	bacteria	NNS
cord-347000-zxytdb0b	306	15	may	may	MD
cord-347000-zxytdb0b	306	16	be	be	VB
cord-347000-zxytdb0b	306	17	present	present	JJ
cord-347000-zxytdb0b	306	18	in	in	IN
cord-347000-zxytdb0b	306	19	such	such	JJ
cord-347000-zxytdb0b	306	20	large	large	JJ
cord-347000-zxytdb0b	306	21	numbers	number	NNS
cord-347000-zxytdb0b	306	22	that	that	IN
cord-347000-zxytdb0b	306	23	it	-PRON-	PRP
cord-347000-zxytdb0b	306	24	is	be	VBZ
cord-347000-zxytdb0b	306	25	more	more	RBR
cord-347000-zxytdb0b	306	26	likely	likely	JJ
cord-347000-zxytdb0b	306	27	that	that	IN
cord-347000-zxytdb0b	306	28	sputum	sputum	NN
cord-347000-zxytdb0b	306	29	was	be	VBD
cord-347000-zxytdb0b	306	30	seeded	seed	VBN
cord-347000-zxytdb0b	306	31	during	during	IN
cord-347000-zxytdb0b	306	32	small	small	JJ
cord-347000-zxytdb0b	306	33	-	-	HYPH
cord-347000-zxytdb0b	306	34	volume	volume	NN
cord-347000-zxytdb0b	306	35	aspiration	aspiration	NN
cord-347000-zxytdb0b	306	36	and	and	CC
cord-347000-zxytdb0b	306	37	multiplication	multiplication	NN
cord-347000-zxytdb0b	306	38	takes	take	VBZ
cord-347000-zxytdb0b	306	39	place	place	NN
cord-347000-zxytdb0b	306	40	in	in	IN
cord-347000-zxytdb0b	306	41	the	the	DT
cord-347000-zxytdb0b	306	42	sputum	sputum	NN
cord-347000-zxytdb0b	306	43	.	.	.
cord-347000-zxytdb0b	307	1	61	61	CD
cord-347000-zxytdb0b	308	1	Two	two	CD
cord-347000-zxytdb0b	308	2	main	main	JJ
cord-347000-zxytdb0b	308	3	lines	line	NNS
cord-347000-zxytdb0b	308	4	of	of	IN
cord-347000-zxytdb0b	308	5	investigation	investigation	NN
cord-347000-zxytdb0b	308	6	have	have	VBP
cord-347000-zxytdb0b	308	7	focused	focus	VBN
cord-347000-zxytdb0b	308	8	on	on	IN
cord-347000-zxytdb0b	308	9	these	these	DT
cord-347000-zxytdb0b	308	10	bacteria	bacteria	NNS
cord-347000-zxytdb0b	308	11	.	.	.
cord-347000-zxytdb0b	309	1	Careful	careful	JJ
cord-347000-zxytdb0b	309	2	culture	culture	NN
cord-347000-zxytdb0b	309	3	techniques	technique	NNS
cord-347000-zxytdb0b	309	4	have	have	VBP
cord-347000-zxytdb0b	309	5	shown	show	VBN
cord-347000-zxytdb0b	309	6	the	the	DT
cord-347000-zxytdb0b	309	7	large	large	JJ
cord-347000-zxytdb0b	309	8	number	number	NN
cord-347000-zxytdb0b	309	9	and	and	CC
cord-347000-zxytdb0b	309	10	diversity	diversity	NN
cord-347000-zxytdb0b	309	11	of	of	IN
cord-347000-zxytdb0b	309	12	anaerobes	anaerobe	NNS
cord-347000-zxytdb0b	309	13	that	that	WDT
cord-347000-zxytdb0b	309	14	can	can	MD
cord-347000-zxytdb0b	309	15	be	be	VB
cord-347000-zxytdb0b	309	16	cultured	culture	VBN
cord-347000-zxytdb0b	309	17	from	from	IN
cord-347000-zxytdb0b	309	18	CF	cf	NN
cord-347000-zxytdb0b	309	19	sputum	sputum	NN
cord-347000-zxytdb0b	309	20	.	.	.
cord-347000-zxytdb0b	310	1	62	62	CD
cord-347000-zxytdb0b	311	1	The	the	DT
cord-347000-zxytdb0b	311	2	use	use	NN
cord-347000-zxytdb0b	311	3	of	of	IN
cord-347000-zxytdb0b	311	4	16s	16s	NNPS
cord-347000-zxytdb0b	311	5	rRNA	rrna	NN
cord-347000-zxytdb0b	311	6	gene	gene	NN
cord-347000-zxytdb0b	311	7	profiling	profiling	NN
cord-347000-zxytdb0b	311	8	by	by	IN
cord-347000-zxytdb0b	311	9	terminal	terminal	JJ
cord-347000-zxytdb0b	311	10	restriction	restriction	NN
cord-347000-zxytdb0b	311	11	fragment	fragment	NN
cord-347000-zxytdb0b	311	12	length	length	NN
cord-347000-zxytdb0b	311	13	polymorphisms	polymorphism	NNS
cord-347000-zxytdb0b	311	14	directly	directly	RB
cord-347000-zxytdb0b	311	15	from	from	IN
cord-347000-zxytdb0b	311	16	CF	cf	NN
cord-347000-zxytdb0b	311	17	sputum	sputum	NN
cord-347000-zxytdb0b	311	18	has	have	VBZ
cord-347000-zxytdb0b	311	19	shown	show	VBN
cord-347000-zxytdb0b	311	20	a	a	DT
cord-347000-zxytdb0b	311	21	great	great	JJ
cord-347000-zxytdb0b	311	22	diversity	diversity	NN
cord-347000-zxytdb0b	311	23	of	of	IN
cord-347000-zxytdb0b	311	24	anaerobic	anaerobic	JJ
cord-347000-zxytdb0b	311	25	and	and	CC
cord-347000-zxytdb0b	311	26	aerobic	aerobic	JJ
cord-347000-zxytdb0b	311	27	species	specie	NNS
cord-347000-zxytdb0b	311	28	.	.	.
cord-347000-zxytdb0b	312	1	63	63	CD
cord-347000-zxytdb0b	313	1	What	what	WP
cord-347000-zxytdb0b	313	2	is	be	VBZ
cord-347000-zxytdb0b	313	3	the	the	DT
cord-347000-zxytdb0b	313	4	significance	significance	NN
cord-347000-zxytdb0b	313	5	of	of	IN
cord-347000-zxytdb0b	313	6	these	these	DT
cord-347000-zxytdb0b	313	7	observations	observation	NNS
cord-347000-zxytdb0b	313	8	?	?	.
cord-347000-zxytdb0b	314	1	It	-PRON-	PRP
cord-347000-zxytdb0b	314	2	may	may	MD
cord-347000-zxytdb0b	314	3	be	be	VB
cord-347000-zxytdb0b	314	4	that	that	IN
cord-347000-zxytdb0b	314	5	these	these	DT
cord-347000-zxytdb0b	314	6	flora	flora	NNS
cord-347000-zxytdb0b	314	7	are	be	VBP
cord-347000-zxytdb0b	314	8	just	just	RB
cord-347000-zxytdb0b	314	9	bystanders	bystander	NNS
cord-347000-zxytdb0b	314	10	(	(	-LRB-
cord-347000-zxytdb0b	314	11	commensals	commensal	NNS
cord-347000-zxytdb0b	314	12	)	)	-RRB-
cord-347000-zxytdb0b	314	13	.	.	.
cord-347000-zxytdb0b	315	1	Alternately	alternately	RB
cord-347000-zxytdb0b	315	2	,	,	,
cord-347000-zxytdb0b	315	3	some	some	DT
cord-347000-zxytdb0b	315	4	may	may	MD
cord-347000-zxytdb0b	315	5	actually	actually	RB
cord-347000-zxytdb0b	315	6	be	be	VB
cord-347000-zxytdb0b	315	7	pathogenic	pathogenic	JJ
cord-347000-zxytdb0b	315	8	and	and	CC
cord-347000-zxytdb0b	315	9	have	have	VBP
cord-347000-zxytdb0b	315	10	been	be	VBN
cord-347000-zxytdb0b	315	11	missed	miss	VBN
cord-347000-zxytdb0b	315	12	because	because	IN
cord-347000-zxytdb0b	315	13	they	-PRON-	PRP
cord-347000-zxytdb0b	315	14	are	be	VBP
cord-347000-zxytdb0b	315	15	present	present	JJ
cord-347000-zxytdb0b	315	16	in	in	IN
cord-347000-zxytdb0b	315	17	a	a	DT
cord-347000-zxytdb0b	315	18	mixture	mixture	NN
cord-347000-zxytdb0b	315	19	with	with	IN
cord-347000-zxytdb0b	315	20	an	an	DT
cord-347000-zxytdb0b	315	21	assumed	assumed	JJ
cord-347000-zxytdb0b	315	22	pathogen	pathogen	NN
cord-347000-zxytdb0b	315	23	such	such	JJ
cord-347000-zxytdb0b	315	24	as	as	IN
cord-347000-zxytdb0b	315	25	P.	P.	NNP
cord-347000-zxytdb0b	315	26	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	315	27	.	.	.
cord-347000-zxytdb0b	316	1	This	this	DT
cord-347000-zxytdb0b	316	2	could	could	MD
cord-347000-zxytdb0b	316	3	even	even	RB
cord-347000-zxytdb0b	316	4	explain	explain	VB
cord-347000-zxytdb0b	316	5	why	why	WRB
cord-347000-zxytdb0b	316	6	CF	cf	NN
cord-347000-zxytdb0b	316	7	patients	patient	NNS
cord-347000-zxytdb0b	316	8	may	may	MD
cord-347000-zxytdb0b	316	9	improve	improve	VB
cord-347000-zxytdb0b	316	10	when	when	WRB
cord-347000-zxytdb0b	316	11	treated	treat	VBN
cord-347000-zxytdb0b	316	12	with	with	IN
cord-347000-zxytdb0b	316	13	antibiotics	antibiotic	NNS
cord-347000-zxytdb0b	316	14	to	to	TO
cord-347000-zxytdb0b	316	15	which	which	WDT
cord-347000-zxytdb0b	316	16	the	the	DT
cord-347000-zxytdb0b	316	17	conventional	conventional	JJ
cord-347000-zxytdb0b	316	18	pathogen	pathogen	NN
cord-347000-zxytdb0b	316	19	is	be	VBZ
cord-347000-zxytdb0b	316	20	resistant	resistant	JJ
cord-347000-zxytdb0b	316	21	in	in	IN
cord-347000-zxytdb0b	316	22	vitro	vitro	FW
cord-347000-zxytdb0b	316	23	.	.	.
cord-347000-zxytdb0b	317	1	27	27	CD
cord-347000-zxytdb0b	318	1	Another	another	DT
cord-347000-zxytdb0b	318	2	explanation	explanation	NN
cord-347000-zxytdb0b	318	3	is	be	VBZ
cord-347000-zxytdb0b	318	4	that	that	IN
cord-347000-zxytdb0b	318	5	members	member	NNS
cord-347000-zxytdb0b	318	6	of	of	IN
cord-347000-zxytdb0b	318	7	the	the	DT
cord-347000-zxytdb0b	318	8	'	'	``
cord-347000-zxytdb0b	318	9	normal	normal	JJ
cord-347000-zxytdb0b	318	10	'	'	''
cord-347000-zxytdb0b	318	11	flora	flora	NNS
cord-347000-zxytdb0b	318	12	may	may	MD
cord-347000-zxytdb0b	318	13	interact	interact	VB
cord-347000-zxytdb0b	318	14	with	with	IN
cord-347000-zxytdb0b	318	15	the	the	DT
cord-347000-zxytdb0b	318	16	conventional	conventional	JJ
cord-347000-zxytdb0b	318	17	pathogen	pathogen	NN
cord-347000-zxytdb0b	318	18	.	.	.
cord-347000-zxytdb0b	319	1	In	in	IN
cord-347000-zxytdb0b	319	2	one	one	CD
cord-347000-zxytdb0b	319	3	study	study	NN
cord-347000-zxytdb0b	319	4	,	,	,
cord-347000-zxytdb0b	319	5	a	a	DT
cord-347000-zxytdb0b	319	6	viridantype	viridantype	NN
cord-347000-zxytdb0b	319	7	Streptococcus	streptococcus	NN
cord-347000-zxytdb0b	319	8	was	be	VBD
cord-347000-zxytdb0b	319	9	shown	show	VBN
cord-347000-zxytdb0b	319	10	to	to	TO
cord-347000-zxytdb0b	319	11	enhance	enhance	VB
cord-347000-zxytdb0b	319	12	the	the	DT
cord-347000-zxytdb0b	319	13	pathogenicity	pathogenicity	NN
cord-347000-zxytdb0b	319	14	of	of	IN
cord-347000-zxytdb0b	319	15	P.	P.	NNP
cord-347000-zxytdb0b	319	16	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	319	17	in	in	IN
cord-347000-zxytdb0b	319	18	an	an	DT
cord-347000-zxytdb0b	319	19	agar	agar	JJ
cord-347000-zxytdb0b	319	20	bead	bead	NN
cord-347000-zxytdb0b	319	21	lung	lung	NN
cord-347000-zxytdb0b	319	22	infection	infection	NN
cord-347000-zxytdb0b	319	23	model	model	NN
cord-347000-zxytdb0b	319	24	in	in	IN
cord-347000-zxytdb0b	319	25	rats	rat	NNS
cord-347000-zxytdb0b	319	26	.	.	.
cord-347000-zxytdb0b	320	1	61	61	CD
cord-347000-zxytdb0b	321	1	This	this	DT
cord-347000-zxytdb0b	321	2	viridans	viridan	VBZ
cord-347000-zxytdb0b	321	3	-	-	HYPH
cord-347000-zxytdb0b	321	4	type	type	NN
cord-347000-zxytdb0b	321	5	Streptococcus	streptococcus	NN
cord-347000-zxytdb0b	321	6	and	and	CC
cord-347000-zxytdb0b	321	7	a	a	DT
cord-347000-zxytdb0b	321	8	coagulase	coagulase	NN
cord-347000-zxytdb0b	321	9	-	-	HYPH
cord-347000-zxytdb0b	321	10	negative	negative	JJ
cord-347000-zxytdb0b	321	11	Staphylococcus	staphylococcus	NN
cord-347000-zxytdb0b	321	12	,	,	,
cord-347000-zxytdb0b	322	1	both	both	DT
cord-347000-zxytdb0b	322	2	isolated	isolate	VBN
cord-347000-zxytdb0b	322	3	from	from	IN
cord-347000-zxytdb0b	322	4	CF	cf	NN
cord-347000-zxytdb0b	322	5	sputum	sputum	NN
cord-347000-zxytdb0b	322	6	,	,	,
cord-347000-zxytdb0b	322	7	also	also	RB
cord-347000-zxytdb0b	322	8	upregulated	upregulate	VBN
cord-347000-zxytdb0b	322	9	P.	p.	NN
cord-347000-zxytdb0b	322	10	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	322	11	genes	gene	NNS
cord-347000-zxytdb0b	322	12	.	.	.
cord-347000-zxytdb0b	323	1	These	these	DT
cord-347000-zxytdb0b	323	2	included	include	VBD
cord-347000-zxytdb0b	323	3	those	those	DT
cord-347000-zxytdb0b	323	4	coding	code	VBG
cord-347000-zxytdb0b	323	5	for	for	IN
cord-347000-zxytdb0b	323	6	pathogenicity	pathogenicity	NN
cord-347000-zxytdb0b	323	7	factors	factor	NNS
cord-347000-zxytdb0b	323	8	such	such	JJ
cord-347000-zxytdb0b	323	9	as	as	IN
cord-347000-zxytdb0b	323	10	elastase	elastase	NN
cord-347000-zxytdb0b	323	11	(	(	-LRB-
cord-347000-zxytdb0b	323	12	lasB	lasB	NNP
cord-347000-zxytdb0b	323	13	)	)	-RRB-
cord-347000-zxytdb0b	323	14	.	.	.
cord-347000-zxytdb0b	324	1	Respiratory	respiratory	JJ
cord-347000-zxytdb0b	324	2	viral	viral	JJ
cord-347000-zxytdb0b	324	3	infections	infection	NNS
cord-347000-zxytdb0b	324	4	are	be	VBP
cord-347000-zxytdb0b	324	5	common	common	JJ
cord-347000-zxytdb0b	324	6	in	in	IN
cord-347000-zxytdb0b	324	7	children	child	NNS
cord-347000-zxytdb0b	324	8	,	,	,
cord-347000-zxytdb0b	324	9	but	but	CC
cord-347000-zxytdb0b	324	10	there	there	EX
cord-347000-zxytdb0b	324	11	have	have	VBP
cord-347000-zxytdb0b	324	12	been	be	VBN
cord-347000-zxytdb0b	324	13	relatively	relatively	RB
cord-347000-zxytdb0b	324	14	few	few	JJ
cord-347000-zxytdb0b	324	15	well	well	RB
cord-347000-zxytdb0b	324	16	-	-	HYPH
cord-347000-zxytdb0b	324	17	controlled	control	VBN
cord-347000-zxytdb0b	324	18	studies	study	NNS
cord-347000-zxytdb0b	324	19	on	on	IN
cord-347000-zxytdb0b	324	20	the	the	DT
cord-347000-zxytdb0b	324	21	specific	specific	JJ
cord-347000-zxytdb0b	324	22	role	role	NN
cord-347000-zxytdb0b	324	23	of	of	IN
cord-347000-zxytdb0b	324	24	respiratory	respiratory	JJ
cord-347000-zxytdb0b	324	25	viruses	virus	NNS
cord-347000-zxytdb0b	324	26	in	in	IN
cord-347000-zxytdb0b	324	27	CF	CF	NNP
cord-347000-zxytdb0b	324	28	.	.	.
cord-347000-zxytdb0b	325	1	64	64	CD
cord-347000-zxytdb0b	326	1	This	this	DT
cord-347000-zxytdb0b	326	2	is	be	VBZ
cord-347000-zxytdb0b	326	3	partly	partly	RB
cord-347000-zxytdb0b	326	4	because	because	IN
cord-347000-zxytdb0b	326	5	the	the	DT
cord-347000-zxytdb0b	326	6	techniques	technique	NNS
cord-347000-zxytdb0b	326	7	for	for	IN
cord-347000-zxytdb0b	326	8	identifying	identify	VBG
cord-347000-zxytdb0b	326	9	viruses	virus	NNS
cord-347000-zxytdb0b	326	10	by	by	IN
cord-347000-zxytdb0b	326	11	culture	culture	NN
cord-347000-zxytdb0b	326	12	or	or	CC
cord-347000-zxytdb0b	326	13	serology	serology	NN
cord-347000-zxytdb0b	326	14	have	have	VBP
cord-347000-zxytdb0b	326	15	been	be	VBN
cord-347000-zxytdb0b	326	16	too	too	RB
cord-347000-zxytdb0b	326	17	insensitive	insensitive	JJ
cord-347000-zxytdb0b	326	18	.	.	.
cord-347000-zxytdb0b	327	1	Respiratory	respiratory	JJ
cord-347000-zxytdb0b	327	2	viruses	virus	NNS
cord-347000-zxytdb0b	327	3	are	be	VBP
cord-347000-zxytdb0b	327	4	thought	think	VBN
cord-347000-zxytdb0b	327	5	to	to	TO
cord-347000-zxytdb0b	327	6	be	be	VB
cord-347000-zxytdb0b	327	7	a	a	DT
cord-347000-zxytdb0b	327	8	trigger	trigger	NN
cord-347000-zxytdb0b	327	9	or	or	CC
cord-347000-zxytdb0b	327	10	co	co	NN
cord-347000-zxytdb0b	327	11	-	-	NN
cord-347000-zxytdb0b	327	12	factor	factor	NN
cord-347000-zxytdb0b	327	13	in	in	IN
cord-347000-zxytdb0b	327	14	acute	acute	JJ
cord-347000-zxytdb0b	327	15	infective	infective	JJ
cord-347000-zxytdb0b	327	16	exacerbations	exacerbation	NNS
cord-347000-zxytdb0b	327	17	of	of	IN
cord-347000-zxytdb0b	327	18	COPD	COPD	NNP
cord-347000-zxytdb0b	327	19	65	65	CD
cord-347000-zxytdb0b	328	1	and	and	CC
cord-347000-zxytdb0b	328	2	it	-PRON-	PRP
cord-347000-zxytdb0b	328	3	has	have	VBZ
cord-347000-zxytdb0b	328	4	been	be	VBN
cord-347000-zxytdb0b	328	5	proposed	propose	VBN
cord-347000-zxytdb0b	328	6	that	that	IN
cord-347000-zxytdb0b	328	7	they	-PRON-	PRP
cord-347000-zxytdb0b	328	8	may	may	MD
cord-347000-zxytdb0b	328	9	play	play	VB
cord-347000-zxytdb0b	328	10	a	a	DT
cord-347000-zxytdb0b	328	11	role	role	NN
cord-347000-zxytdb0b	328	12	in	in	IN
cord-347000-zxytdb0b	328	13	developing	develop	VBG
cord-347000-zxytdb0b	328	14	chronic	chronic	JJ
cord-347000-zxytdb0b	328	15	infection	infection	NN
cord-347000-zxytdb0b	328	16	with	with	IN
cord-347000-zxytdb0b	328	17	bacterial	bacterial	JJ
cord-347000-zxytdb0b	328	18	pathogens	pathogen	NNS
cord-347000-zxytdb0b	328	19	.	.	.
cord-347000-zxytdb0b	329	1	Early	early	JJ
cord-347000-zxytdb0b	329	2	Danish	danish	JJ
cord-347000-zxytdb0b	329	3	data	datum	NNS
cord-347000-zxytdb0b	329	4	showed	show	VBD
cord-347000-zxytdb0b	329	5	that	that	IN
cord-347000-zxytdb0b	329	6	CF	cf	NN
cord-347000-zxytdb0b	329	7	patients	patient	NNS
cord-347000-zxytdb0b	329	8	were	be	VBD
cord-347000-zxytdb0b	329	9	more	more	RBR
cord-347000-zxytdb0b	329	10	likely	likely	JJ
cord-347000-zxytdb0b	329	11	to	to	TO
cord-347000-zxytdb0b	329	12	acquire	acquire	VB
cord-347000-zxytdb0b	329	13	their	-PRON-	PRP$
cord-347000-zxytdb0b	329	14	first	first	JJ
cord-347000-zxytdb0b	329	15	P.	p.	NN
cord-347000-zxytdb0b	329	16	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	329	17	or	or	CC
cord-347000-zxytdb0b	329	18	develop	develop	VB
cord-347000-zxytdb0b	329	19	chronic	chronic	JJ
cord-347000-zxytdb0b	329	20	pseudomonal	pseudomonal	JJ
cord-347000-zxytdb0b	329	21	infection	infection	NN
cord-347000-zxytdb0b	329	22	between	between	IN
cord-347000-zxytdb0b	329	23	October	October	NNP
cord-347000-zxytdb0b	329	24	and	and	CC
cord-347000-zxytdb0b	329	25	March	March	NNP
cord-347000-zxytdb0b	329	26	-	-	:
cord-347000-zxytdb0b	329	27	the	the	DT
cord-347000-zxytdb0b	329	28	peak	peak	NN
cord-347000-zxytdb0b	329	29	season	season	NN
cord-347000-zxytdb0b	329	30	for	for	IN
cord-347000-zxytdb0b	329	31	respiratory	respiratory	JJ
cord-347000-zxytdb0b	329	32	viruses	virus	NNS
cord-347000-zxytdb0b	329	33	.	.	.
cord-347000-zxytdb0b	330	1	This	this	DT
cord-347000-zxytdb0b	330	2	finding	finding	NN
cord-347000-zxytdb0b	330	3	was	be	VBD
cord-347000-zxytdb0b	330	4	consistent	consistent	JJ
cord-347000-zxytdb0b	330	5	over	over	IN
cord-347000-zxytdb0b	330	6	25	25	CD
cord-347000-zxytdb0b	330	7	years	year	NNS
cord-347000-zxytdb0b	330	8	in	in	IN
cord-347000-zxytdb0b	330	9	spite	spite	NN
cord-347000-zxytdb0b	330	10	of	of	IN
cord-347000-zxytdb0b	330	11	major	major	JJ
cord-347000-zxytdb0b	330	12	changes	change	NNS
cord-347000-zxytdb0b	330	13	in	in	IN
cord-347000-zxytdb0b	330	14	treatment	treatment	NN
cord-347000-zxytdb0b	330	15	of	of	IN
cord-347000-zxytdb0b	330	16	bacterial	bacterial	JJ
cord-347000-zxytdb0b	330	17	infection	infection	NN
cord-347000-zxytdb0b	330	18	.	.	.
cord-347000-zxytdb0b	331	1	The	the	DT
cord-347000-zxytdb0b	331	2	rapid	rapid	JJ
cord-347000-zxytdb0b	331	3	technical	technical	JJ
cord-347000-zxytdb0b	331	4	advances	advance	NNS
cord-347000-zxytdb0b	331	5	,	,	,
cord-347000-zxytdb0b	331	6	for	for	IN
cord-347000-zxytdb0b	331	7	examples	example	NNS
cord-347000-zxytdb0b	331	8	,	,	,
cord-347000-zxytdb0b	331	9	with	with	IN
cord-347000-zxytdb0b	331	10	the	the	DT
cord-347000-zxytdb0b	331	11	use	use	NN
cord-347000-zxytdb0b	331	12	of	of	IN
cord-347000-zxytdb0b	331	13	micro	micro	NNS
cord-347000-zxytdb0b	331	14	-	-	NNS
cord-347000-zxytdb0b	331	15	arrays	array	NNS
cord-347000-zxytdb0b	331	16	,	,	,
cord-347000-zxytdb0b	331	17	should	should	MD
cord-347000-zxytdb0b	331	18	allow	allow	VB
cord-347000-zxytdb0b	331	19	more	more	JJR
cord-347000-zxytdb0b	331	20	in	in	IN
cord-347000-zxytdb0b	331	21	-	-	HYPH
cord-347000-zxytdb0b	331	22	depth	depth	NN
cord-347000-zxytdb0b	331	23	studies	study	NNS
cord-347000-zxytdb0b	331	24	of	of	IN
cord-347000-zxytdb0b	331	25	the	the	DT
cord-347000-zxytdb0b	331	26	role	role	NN
cord-347000-zxytdb0b	331	27	of	of	IN
cord-347000-zxytdb0b	331	28	viral	viral	JJ
cord-347000-zxytdb0b	331	29	infections	infection	NNS
cord-347000-zxytdb0b	331	30	in	in	IN
cord-347000-zxytdb0b	331	31	CF	CF	NNP
cord-347000-zxytdb0b	331	32	.	.	.
cord-347000-zxytdb0b	332	1	66	66	CD
cord-347000-zxytdb0b	333	1	Influenza	Influenza	NNP
cord-347000-zxytdb0b	333	2	A	A	NNP
cord-347000-zxytdb0b	333	3	can	can	MD
cord-347000-zxytdb0b	333	4	have	have	VB
cord-347000-zxytdb0b	333	5	a	a	DT
cord-347000-zxytdb0b	333	6	significant	significant	JJ
cord-347000-zxytdb0b	333	7	impact	impact	NN
cord-347000-zxytdb0b	333	8	in	in	IN
cord-347000-zxytdb0b	333	9	patients	patient	NNS
cord-347000-zxytdb0b	333	10	with	with	IN
cord-347000-zxytdb0b	333	11	CF	CF	NNP
cord-347000-zxytdb0b	333	12	.	.	.
cord-347000-zxytdb0b	334	1	Anti	anti	JJ
cord-347000-zxytdb0b	334	2	-	-	JJ
cord-347000-zxytdb0b	334	3	viral	viral	JJ
cord-347000-zxytdb0b	334	4	drugs	drug	NNS
cord-347000-zxytdb0b	334	5	are	be	VBP
cord-347000-zxytdb0b	334	6	recommended	recommend	VBN
cord-347000-zxytdb0b	334	7	in	in	IN
cord-347000-zxytdb0b	334	8	the	the	DT
cord-347000-zxytdb0b	334	9	UK	UK	NNP
cord-347000-zxytdb0b	334	10	for	for	IN
cord-347000-zxytdb0b	334	11	patients	patient	NNS
cord-347000-zxytdb0b	334	12	with	with	IN
cord-347000-zxytdb0b	334	13	chronic	chronic	JJ
cord-347000-zxytdb0b	334	14	lung	lung	NN
cord-347000-zxytdb0b	334	15	disease	disease	NN
cord-347000-zxytdb0b	334	16	including	include	VBG
cord-347000-zxytdb0b	334	17	CF	CF	NNP
cord-347000-zxytdb0b	334	18	,	,	,
cord-347000-zxytdb0b	334	19	both	both	DT
cord-347000-zxytdb0b	334	20	for	for	IN
cord-347000-zxytdb0b	334	21	treatment	treatment	NN
cord-347000-zxytdb0b	334	22	and	and	CC
cord-347000-zxytdb0b	334	23	prevention	prevention	NN
cord-347000-zxytdb0b	334	24	after	after	IN
cord-347000-zxytdb0b	334	25	exposure	exposure	NN
cord-347000-zxytdb0b	334	26	.	.	.
cord-347000-zxytdb0b	335	1	Annual	annual	JJ
cord-347000-zxytdb0b	335	2	vaccination	vaccination	NN
cord-347000-zxytdb0b	335	3	is	be	VBZ
cord-347000-zxytdb0b	335	4	also	also	RB
cord-347000-zxytdb0b	335	5	recommended	recommend	VBN
cord-347000-zxytdb0b	335	6	for	for	IN
cord-347000-zxytdb0b	335	7	patients	patient	NNS
cord-347000-zxytdb0b	335	8	with	with	IN
cord-347000-zxytdb0b	335	9	CF	CF	NNP
cord-347000-zxytdb0b	335	10	.	.	.
cord-347000-zxytdb0b	336	1	The	the	DT
cord-347000-zxytdb0b	336	2	microbiology	microbiology	NN
cord-347000-zxytdb0b	336	3	of	of	IN
cord-347000-zxytdb0b	336	4	CF	CF	NNP
cord-347000-zxytdb0b	336	5	is	be	VBZ
cord-347000-zxytdb0b	336	6	complex	complex	JJ
cord-347000-zxytdb0b	336	7	.	.	.
cord-347000-zxytdb0b	337	1	A	a	DT
cord-347000-zxytdb0b	337	2	pattern	pattern	NN
cord-347000-zxytdb0b	337	3	of	of	IN
cord-347000-zxytdb0b	337	4	acute	acute	JJ
cord-347000-zxytdb0b	337	5	,	,	,
cord-347000-zxytdb0b	337	6	intermittent	intermittent	JJ
cord-347000-zxytdb0b	337	7	and	and	CC
cord-347000-zxytdb0b	337	8	eventually	eventually	RB
cord-347000-zxytdb0b	337	9	chronic	chronic	JJ
cord-347000-zxytdb0b	337	10	infection	infection	NN
cord-347000-zxytdb0b	337	11	is	be	VBZ
cord-347000-zxytdb0b	337	12	seen	see	VBN
cord-347000-zxytdb0b	337	13	.	.	.
cord-347000-zxytdb0b	338	1	Both	both	DT
cord-347000-zxytdb0b	338	2	familiar	familiar	JJ
cord-347000-zxytdb0b	338	3	pathogens	pathogen	NNS
cord-347000-zxytdb0b	338	4	and	and	CC
cord-347000-zxytdb0b	338	5	bacteria	bacteria	NNS
cord-347000-zxytdb0b	338	6	not	not	RB
cord-347000-zxytdb0b	338	7	normally	normally	RB
cord-347000-zxytdb0b	338	8	seen	see	VBN
cord-347000-zxytdb0b	338	9	in	in	IN
cord-347000-zxytdb0b	338	10	the	the	DT
cord-347000-zxytdb0b	338	11	respiratory	respiratory	JJ
cord-347000-zxytdb0b	338	12	tract	tract	NN
cord-347000-zxytdb0b	338	13	are	be	VBP
cord-347000-zxytdb0b	338	14	encountered	encounter	VBN
cord-347000-zxytdb0b	338	15	.	.	.
cord-347000-zxytdb0b	339	1	The	the	DT
cord-347000-zxytdb0b	339	2	relevance	relevance	NN
cord-347000-zxytdb0b	339	3	of	of	IN
cord-347000-zxytdb0b	339	4	new	new	JJ
cord-347000-zxytdb0b	339	5	insights	insight	NNS
cord-347000-zxytdb0b	339	6	into	into	IN
cord-347000-zxytdb0b	339	7	the	the	DT
cord-347000-zxytdb0b	339	8	pathogenicity	pathogenicity	NN
cord-347000-zxytdb0b	339	9	and	and	CC
cord-347000-zxytdb0b	339	10	epidemiology	epidemiology	NN
cord-347000-zxytdb0b	339	11	of	of	IN
cord-347000-zxytdb0b	339	12	old	old	JJ
cord-347000-zxytdb0b	339	13	pathogens	pathogen	NNS
cord-347000-zxytdb0b	339	14	in	in	IN
cord-347000-zxytdb0b	339	15	CF	CF	NNP
cord-347000-zxytdb0b	339	16	is	be	VBZ
cord-347000-zxytdb0b	339	17	being	be	VBG
cord-347000-zxytdb0b	339	18	assessed	assess	VBN
cord-347000-zxytdb0b	339	19	and	and	CC
cord-347000-zxytdb0b	339	20	the	the	DT
cord-347000-zxytdb0b	339	21	significance	significance	NN
cord-347000-zxytdb0b	339	22	of	of	IN
cord-347000-zxytdb0b	339	23	other	other	JJ
cord-347000-zxytdb0b	339	24	micro	micro	NNS
cord-347000-zxytdb0b	339	25	-	-	NNS
cord-347000-zxytdb0b	339	26	organisms	organism	NNS
cord-347000-zxytdb0b	339	27	,	,	,
cord-347000-zxytdb0b	339	28	previously	previously	RB
cord-347000-zxytdb0b	339	29	not	not	RB
cord-347000-zxytdb0b	339	30	recognized	recognize	VBN
cord-347000-zxytdb0b	339	31	in	in	IN
cord-347000-zxytdb0b	339	32	CF	CF	NNP
cord-347000-zxytdb0b	339	33	,	,	,
cord-347000-zxytdb0b	339	34	is	be	VBZ
cord-347000-zxytdb0b	339	35	being	be	VBG
cord-347000-zxytdb0b	339	36	investigated	investigate	VBN
cord-347000-zxytdb0b	339	37	.	.	.
cord-347000-zxytdb0b	340	1	Although	although	IN
cord-347000-zxytdb0b	340	2	there	there	EX
cord-347000-zxytdb0b	340	3	have	have	VBP
cord-347000-zxytdb0b	340	4	been	be	VBN
cord-347000-zxytdb0b	340	5	exciting	exciting	JJ
cord-347000-zxytdb0b	340	6	advances	advance	NNS
cord-347000-zxytdb0b	340	7	in	in	IN
cord-347000-zxytdb0b	340	8	basic	basic	JJ
cord-347000-zxytdb0b	340	9	science	science	NN
cord-347000-zxytdb0b	340	10	,	,	,
cord-347000-zxytdb0b	340	11	we	-PRON-	PRP
cord-347000-zxytdb0b	340	12	still	still	RB
cord-347000-zxytdb0b	340	13	need	need	VBP
cord-347000-zxytdb0b	340	14	to	to	TO
cord-347000-zxytdb0b	340	15	understand	understand	VB
cord-347000-zxytdb0b	340	16	what	what	WP
cord-347000-zxytdb0b	340	17	triggers	trigger	VBZ
cord-347000-zxytdb0b	340	18	exacerbations	exacerbation	NNS
cord-347000-zxytdb0b	340	19	,	,	,
cord-347000-zxytdb0b	340	20	how	how	WRB
cord-347000-zxytdb0b	340	21	to	to	TO
cord-347000-zxytdb0b	340	22	test	test	VB
cord-347000-zxytdb0b	340	23	bacteria	bacteria	NNS
cord-347000-zxytdb0b	340	24	from	from	IN
cord-347000-zxytdb0b	340	25	CF	CF	NNP
cord-347000-zxytdb0b	340	26	in	in	IN
cord-347000-zxytdb0b	340	27	the	the	DT
cord-347000-zxytdb0b	340	28	laboratory	laboratory	NN
cord-347000-zxytdb0b	340	29	for	for	IN
cord-347000-zxytdb0b	340	30	the	the	DT
cord-347000-zxytdb0b	340	31	most	most	RBS
cord-347000-zxytdb0b	340	32	accurate	accurate	JJ
cord-347000-zxytdb0b	340	33	and	and	CC
cord-347000-zxytdb0b	340	34	clinically	clinically	RB
cord-347000-zxytdb0b	340	35	relevant	relevant	JJ
cord-347000-zxytdb0b	340	36	results	result	NNS
cord-347000-zxytdb0b	340	37	,	,	,
cord-347000-zxytdb0b	340	38	and	and	CC
cord-347000-zxytdb0b	340	39	what	what	WP
cord-347000-zxytdb0b	340	40	are	be	VBP
cord-347000-zxytdb0b	340	41	the	the	DT
cord-347000-zxytdb0b	340	42	best	good	JJS
cord-347000-zxytdb0b	340	43	options	option	NNS
cord-347000-zxytdb0b	340	44	for	for	IN
cord-347000-zxytdb0b	340	45	prevention	prevention	NN
cord-347000-zxytdb0b	340	46	and	and	CC
cord-347000-zxytdb0b	340	47	treatment	treatment	NN
cord-347000-zxytdb0b	340	48	of	of	IN
cord-347000-zxytdb0b	340	49	infection	infection	NN
cord-347000-zxytdb0b	340	50	.	.	.
cord-347000-zxytdb0b	341	1	Lesson	lesson	NN
cord-347000-zxytdb0b	341	2	learned	learn	VBD
cord-347000-zxytdb0b	341	3	from	from	IN
cord-347000-zxytdb0b	341	4	the	the	DT
cord-347000-zxytdb0b	341	5	complex	complex	JJ
cord-347000-zxytdb0b	341	6	interactions	interaction	NNS
cord-347000-zxytdb0b	341	7	between	between	IN
cord-347000-zxytdb0b	341	8	bacteria	bacteria	NNS
cord-347000-zxytdb0b	341	9	and	and	CC
cord-347000-zxytdb0b	341	10	adaptations	adaptation	NNS
cord-347000-zxytdb0b	341	11	to	to	IN
cord-347000-zxytdb0b	341	12	chronic	chronic	JJ
cord-347000-zxytdb0b	341	13	infection	infection	NN
cord-347000-zxytdb0b	341	14	seen	see	VBN
cord-347000-zxytdb0b	341	15	in	in	IN
cord-347000-zxytdb0b	341	16	the	the	DT
cord-347000-zxytdb0b	341	17	CF	CF	NNP
cord-347000-zxytdb0b	341	18	lung	lung	NN
cord-347000-zxytdb0b	341	19	hold	hold	VBP
cord-347000-zxytdb0b	341	20	promise	promise	NN
cord-347000-zxytdb0b	341	21	for	for	IN
cord-347000-zxytdb0b	341	22	better	well	JJR
cord-347000-zxytdb0b	341	23	management	management	NN
cord-347000-zxytdb0b	341	24	of	of	IN
cord-347000-zxytdb0b	341	25	infection	infection	NN
cord-347000-zxytdb0b	341	26	in	in	IN
cord-347000-zxytdb0b	341	27	CF	CF	NNP
cord-347000-zxytdb0b	341	28	.	.	.
cord-347000-zxytdb0b	342	1	These	these	DT
cord-347000-zxytdb0b	342	2	may	may	MD
cord-347000-zxytdb0b	342	3	also	also	RB
cord-347000-zxytdb0b	342	4	help	help	VB
cord-347000-zxytdb0b	342	5	develop	develop	VB
cord-347000-zxytdb0b	342	6	strategies	strategy	NNS
cord-347000-zxytdb0b	342	7	to	to	TO
cord-347000-zxytdb0b	342	8	improve	improve	VB
cord-347000-zxytdb0b	342	9	the	the	DT
cord-347000-zxytdb0b	342	10	outcome	outcome	NN
cord-347000-zxytdb0b	342	11	of	of	IN
cord-347000-zxytdb0b	342	12	other	other	JJ
cord-347000-zxytdb0b	342	13	chronic	chronic	JJ
cord-347000-zxytdb0b	342	14	infections	infection	NNS
cord-347000-zxytdb0b	342	15	,	,	,
cord-347000-zxytdb0b	342	16	both	both	CC
cord-347000-zxytdb0b	342	17	in	in	IN
cord-347000-zxytdb0b	342	18	the	the	DT
cord-347000-zxytdb0b	342	19	lung	lung	NN
cord-347000-zxytdb0b	342	20	and	and	CC
cord-347000-zxytdb0b	342	21	elsewhere	elsewhere	RB
cord-347000-zxytdb0b	342	22	.	.	.
cord-347000-zxytdb0b	343	1	Microbiology	microbiology	NN
cord-347000-zxytdb0b	343	2	of	of	IN
cord-347000-zxytdb0b	343	3	sputum	sputum	NN
cord-347000-zxytdb0b	343	4	from	from	IN
cord-347000-zxytdb0b	343	5	patients	patient	NNS
cord-347000-zxytdb0b	343	6	at	at	IN
cord-347000-zxytdb0b	343	7	cystic	cystic	JJ
cord-347000-zxytdb0b	343	8	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	343	9	centers	center	NNS
cord-347000-zxytdb0b	343	10	in	in	IN
cord-347000-zxytdb0b	343	11	the	the	DT
cord-347000-zxytdb0b	343	12	United	United	NNP
cord-347000-zxytdb0b	343	13	States	States	NNP
cord-347000-zxytdb0b	343	14	Microbiology	Microbiology	NNP
cord-347000-zxytdb0b	343	15	of	of	IN
cord-347000-zxytdb0b	343	16	lung	lung	NN
cord-347000-zxytdb0b	343	17	infection	infection	NN
cord-347000-zxytdb0b	343	18	in	in	IN
cord-347000-zxytdb0b	343	19	cystic	cystic	JJ
cord-347000-zxytdb0b	343	20	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	343	21	Persistent	persistent	JJ
cord-347000-zxytdb0b	343	22	and	and	CC
cord-347000-zxytdb0b	343	23	aggressive	aggressive	JJ
cord-347000-zxytdb0b	343	24	bacteria	bacteria	NNS
cord-347000-zxytdb0b	343	25	in	in	IN
cord-347000-zxytdb0b	343	26	the	the	DT
cord-347000-zxytdb0b	343	27	lungs	lung	NNS
cord-347000-zxytdb0b	343	28	of	of	IN
cord-347000-zxytdb0b	343	29	cystic	cystic	JJ
cord-347000-zxytdb0b	343	30	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	343	31	children	child	NNS
cord-347000-zxytdb0b	343	32	Report	Report	NNP
cord-347000-zxytdb0b	343	33	of	of	IN
cord-347000-zxytdb0b	343	34	the	the	DT
cord-347000-zxytdb0b	343	35	UK	UK	NNP
cord-347000-zxytdb0b	343	36	Cystic	Cystic	NNP
cord-347000-zxytdb0b	343	37	Fibrosis	Fibrosis	NNP
cord-347000-zxytdb0b	343	38	Trust	Trust	NNP
cord-347000-zxytdb0b	343	39	's	's	POS
cord-347000-zxytdb0b	343	40	Antibiotic	Antibiotic	NNP
cord-347000-zxytdb0b	343	41	Group	Group	NNP
cord-347000-zxytdb0b	343	42	Current	Current	NNP
cord-347000-zxytdb0b	343	43	and	and	CC
cord-347000-zxytdb0b	343	44	novel	novel	JJ
cord-347000-zxytdb0b	343	45	antimicrobial	antimicrobial	NN
cord-347000-zxytdb0b	343	46	approaches	approach	NNS
cord-347000-zxytdb0b	344	1	Lower	low	JJR
cord-347000-zxytdb0b	344	2	respiratory	respiratory	JJ
cord-347000-zxytdb0b	344	3	infection	infection	NN
cord-347000-zxytdb0b	344	4	and	and	CC
cord-347000-zxytdb0b	344	5	inflammation	inflammation	NN
cord-347000-zxytdb0b	344	6	in	in	IN
cord-347000-zxytdb0b	344	7	infants	infant	NNS
cord-347000-zxytdb0b	344	8	with	with	IN
cord-347000-zxytdb0b	344	9	newly	newly	RB
cord-347000-zxytdb0b	344	10	diagnosed	diagnose	VBN
cord-347000-zxytdb0b	344	11	cystic	cystic	JJ
cord-347000-zxytdb0b	344	12	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	344	13	Population	population	NN
cord-347000-zxytdb0b	344	14	dynamics	dynamic	NNS
cord-347000-zxytdb0b	344	15	of	of	IN
cord-347000-zxytdb0b	344	16	persistent	persistent	JJ
cord-347000-zxytdb0b	344	17	Staphylococcus	Staphylococcus	NNP
cord-347000-zxytdb0b	344	18	aureus	aureu	NNS
cord-347000-zxytdb0b	344	19	isolated	isolate	VBN
cord-347000-zxytdb0b	344	20	from	from	IN
cord-347000-zxytdb0b	344	21	the	the	DT
cord-347000-zxytdb0b	344	22	airways	airways	NNPS
cord-347000-zxytdb0b	344	23	of	of	IN
cord-347000-zxytdb0b	344	24	cystic	cystic	JJ
cord-347000-zxytdb0b	344	25	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	344	26	patients	patient	NNS
cord-347000-zxytdb0b	344	27	during	during	IN
cord-347000-zxytdb0b	344	28	a	a	DT
cord-347000-zxytdb0b	344	29	6-year	6-year	JJ
cord-347000-zxytdb0b	344	30	prospective	prospective	JJ
cord-347000-zxytdb0b	344	31	study	study	NN
cord-347000-zxytdb0b	344	32	Prophylactic	prophylactic	JJ
cord-347000-zxytdb0b	344	33	antibiotics	antibiotic	NNS
cord-347000-zxytdb0b	344	34	for	for	IN
cord-347000-zxytdb0b	344	35	cystic	cystic	JJ
cord-347000-zxytdb0b	344	36	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	344	37	Increased	increase	VBN
cord-347000-zxytdb0b	344	38	frequency	frequency	NN
cord-347000-zxytdb0b	344	39	of	of	IN
cord-347000-zxytdb0b	344	40	genomic	genomic	JJ
cord-347000-zxytdb0b	344	41	alterations	alteration	NNS
cord-347000-zxytdb0b	344	42	in	in	IN
cord-347000-zxytdb0b	344	43	Staphylococcus	Staphylococcus	NNP
cord-347000-zxytdb0b	344	44	aureus	aureus	NN
cord-347000-zxytdb0b	344	45	during	during	IN
cord-347000-zxytdb0b	344	46	chronic	chronic	JJ
cord-347000-zxytdb0b	344	47	infection	infection	NN
cord-347000-zxytdb0b	344	48	is	be	VBZ
cord-347000-zxytdb0b	344	49	in	in	IN
cord-347000-zxytdb0b	344	50	part	part	NN
cord-347000-zxytdb0b	344	51	due	due	IN
cord-347000-zxytdb0b	344	52	to	to	IN
cord-347000-zxytdb0b	344	53	phage	phage	NN
cord-347000-zxytdb0b	344	54	mobilization	mobilization	NN
cord-347000-zxytdb0b	344	55	High	high	JJ
cord-347000-zxytdb0b	344	56	rate	rate	NN
cord-347000-zxytdb0b	344	57	of	of	IN
cord-347000-zxytdb0b	344	58	macrolide	macrolide	JJ
cord-347000-zxytdb0b	344	59	resistance	resistance	NN
cord-347000-zxytdb0b	344	60	in	in	IN
cord-347000-zxytdb0b	344	61	Staphylococcus	Staphylococcus	NNP
cord-347000-zxytdb0b	344	62	aureus	aureus	NN
cord-347000-zxytdb0b	344	63	strains	strain	VBZ
cord-347000-zxytdb0b	344	64	from	from	IN
cord-347000-zxytdb0b	344	65	patients	patient	NNS
cord-347000-zxytdb0b	344	66	with	with	IN
cord-347000-zxytdb0b	344	67	cystic	cystic	JJ
cord-347000-zxytdb0b	344	68	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	344	69	reveals	reveal	VBZ
cord-347000-zxytdb0b	344	70	high	high	JJ
cord-347000-zxytdb0b	344	71	proportions	proportion	NNS
cord-347000-zxytdb0b	344	72	of	of	IN
cord-347000-zxytdb0b	344	73	hypermutable	hypermutable	JJ
cord-347000-zxytdb0b	344	74	strains	strain	NNS
cord-347000-zxytdb0b	344	75	Guidelines	guideline	NNS
cord-347000-zxytdb0b	344	76	for	for	IN
cord-347000-zxytdb0b	344	77	the	the	DT
cord-347000-zxytdb0b	344	78	control	control	NN
cord-347000-zxytdb0b	344	79	and	and	CC
cord-347000-zxytdb0b	344	80	prevention	prevention	NN
cord-347000-zxytdb0b	344	81	of	of	IN
cord-347000-zxytdb0b	344	82	methicillin	methicillin	NN
cord-347000-zxytdb0b	344	83	-	-	HYPH
cord-347000-zxytdb0b	344	84	resistant	resistant	JJ
cord-347000-zxytdb0b	344	85	Staphylococcus	Staphylococcus	NNP
cord-347000-zxytdb0b	344	86	aureus	aureus	NN
cord-347000-zxytdb0b	344	87	(	(	-LRB-
cord-347000-zxytdb0b	344	88	MRSA	MRSA	NNP
cord-347000-zxytdb0b	344	89	)	)	-RRB-
cord-347000-zxytdb0b	344	90	in	in	IN
cord-347000-zxytdb0b	344	91	healthcare	healthcare	NN
cord-347000-zxytdb0b	344	92	facilities	facility	NNS
cord-347000-zxytdb0b	344	93	National	national	JJ
cord-347000-zxytdb0b	344	94	survey	survey	NN
cord-347000-zxytdb0b	344	95	of	of	IN
cord-347000-zxytdb0b	344	96	molecular	molecular	JJ
cord-347000-zxytdb0b	344	97	epidemiology	epidemiology	NN
cord-347000-zxytdb0b	344	98	of	of	IN
cord-347000-zxytdb0b	344	99	Staphylococcus	Staphylococcus	NNP
cord-347000-zxytdb0b	344	100	aureus	aureus	NN
cord-347000-zxytdb0b	344	101	colonization	colonization	NN
cord-347000-zxytdb0b	344	102	in	in	IN
cord-347000-zxytdb0b	344	103	Belgian	belgian	JJ
cord-347000-zxytdb0b	344	104	cystic	cystic	JJ
cord-347000-zxytdb0b	344	105	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	344	106	patients	patient	NNS
cord-347000-zxytdb0b	344	107	Successful	successful	JJ
cord-347000-zxytdb0b	344	108	decolonization	decolonization	NN
cord-347000-zxytdb0b	344	109	of	of	IN
cord-347000-zxytdb0b	344	110	methicillinresistant	methicillinresistant	JJ
cord-347000-zxytdb0b	344	111	Staphylococcus	Staphylococcus	NNP
cord-347000-zxytdb0b	344	112	aureus	aureus	NN
cord-347000-zxytdb0b	344	113	in	in	IN
cord-347000-zxytdb0b	344	114	paediatric	paediatric	JJ
cord-347000-zxytdb0b	344	115	patients	patient	NNS
cord-347000-zxytdb0b	344	116	with	with	IN
cord-347000-zxytdb0b	344	117	cystic	cystic	JJ
cord-347000-zxytdb0b	344	118	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	344	119	(	(	-LRB-
cord-347000-zxytdb0b	344	120	CF	CF	NNP
cord-347000-zxytdb0b	344	121	)	)	-RRB-
cord-347000-zxytdb0b	344	122	using	use	VBG
cord-347000-zxytdb0b	344	123	a	a	DT
cord-347000-zxytdb0b	344	124	threestep	threestep	NN
cord-347000-zxytdb0b	344	125	protocol	protocol	NN
cord-347000-zxytdb0b	344	126	Dynamics	dynamic	NNS
cord-347000-zxytdb0b	344	127	of	of	IN
cord-347000-zxytdb0b	344	128	long	long	JJ
cord-347000-zxytdb0b	344	129	-	-	HYPH
cord-347000-zxytdb0b	344	130	term	term	NN
cord-347000-zxytdb0b	344	131	colonization	colonization	NN
cord-347000-zxytdb0b	344	132	of	of	IN
cord-347000-zxytdb0b	344	133	respiratory	respiratory	JJ
cord-347000-zxytdb0b	344	134	tract	tract	NN
cord-347000-zxytdb0b	344	135	by	by	IN
cord-347000-zxytdb0b	344	136	Haemophilus	Haemophilus	NNP
cord-347000-zxytdb0b	344	137	influenzae	influenzae	NN
cord-347000-zxytdb0b	344	138	in	in	IN
cord-347000-zxytdb0b	344	139	cystic	cystic	JJ
cord-347000-zxytdb0b	344	140	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	344	141	patients	patient	NNS
cord-347000-zxytdb0b	344	142	shows	show	VBZ
cord-347000-zxytdb0b	344	143	a	a	DT
cord-347000-zxytdb0b	344	144	marked	marked	JJ
cord-347000-zxytdb0b	344	145	increase	increase	NN
cord-347000-zxytdb0b	344	146	in	in	IN
cord-347000-zxytdb0b	344	147	hypermutable	hypermutable	JJ
cord-347000-zxytdb0b	344	148	strains	strain	NNS
cord-347000-zxytdb0b	344	149	Hypermutable	hypermutable	JJ
cord-347000-zxytdb0b	344	150	Haemophilus	Haemophilus	NNP
cord-347000-zxytdb0b	344	151	influenzae	influenzae	NN
cord-347000-zxytdb0b	344	152	with	with	IN
cord-347000-zxytdb0b	344	153	mutations	mutation	NNS
cord-347000-zxytdb0b	344	154	in	in	IN
cord-347000-zxytdb0b	344	155	mutS	muts	CD
cord-347000-zxytdb0b	344	156	are	be	VBP
cord-347000-zxytdb0b	344	157	found	find	VBN
cord-347000-zxytdb0b	344	158	in	in	IN
cord-347000-zxytdb0b	344	159	cystic	cystic	JJ
cord-347000-zxytdb0b	344	160	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	344	161	sputum	sputum	NN
cord-347000-zxytdb0b	344	162	Subinhibitory	Subinhibitory	NNP
cord-347000-zxytdb0b	344	163	concentrations	concentration	NNS
cord-347000-zxytdb0b	344	164	of	of	IN
cord-347000-zxytdb0b	344	165	azithromycin	azithromycin	NNP
cord-347000-zxytdb0b	344	166	decrease	decrease	VB
cord-347000-zxytdb0b	344	167	nontypeable	nontypeable	JJ
cord-347000-zxytdb0b	344	168	Haemophilus	haemophilus	JJ
cord-347000-zxytdb0b	344	169	influenzae	influenzae	NN
cord-347000-zxytdb0b	344	170	biofilm	biofilm	NN
cord-347000-zxytdb0b	344	171	formation	formation	NN
cord-347000-zxytdb0b	344	172	and	and	CC
cord-347000-zxytdb0b	344	173	Diminish	diminish	VB
cord-347000-zxytdb0b	344	174	established	establish	VBN
cord-347000-zxytdb0b	344	175	biofilms	biofilm	NNS
cord-347000-zxytdb0b	344	176	Population	population	NN
cord-347000-zxytdb0b	344	177	structure	structure	NN
cord-347000-zxytdb0b	344	178	,	,	,
cord-347000-zxytdb0b	344	179	antimicrobial	antimicrobial	JJ
cord-347000-zxytdb0b	344	180	resistance	resistance	NN
cord-347000-zxytdb0b	344	181	,	,	,
cord-347000-zxytdb0b	344	182	and	and	CC
cord-347000-zxytdb0b	344	183	mutation	mutation	NN
cord-347000-zxytdb0b	344	184	frequencies	frequency	NNS
cord-347000-zxytdb0b	344	185	of	of	IN
cord-347000-zxytdb0b	344	186	Streptococcus	Streptococcus	NNP
cord-347000-zxytdb0b	344	187	pneumoniae	pneumoniae	NN
cord-347000-zxytdb0b	344	188	isolates	isolate	VBZ
cord-347000-zxytdb0b	344	189	from	from	IN
cord-347000-zxytdb0b	344	190	cystic	cystic	JJ
cord-347000-zxytdb0b	344	191	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	344	192	patients	patient	NNS
cord-347000-zxytdb0b	344	193	Differences	difference	NNS
cord-347000-zxytdb0b	344	194	in	in	IN
cord-347000-zxytdb0b	344	195	biofilm	biofilm	NN
cord-347000-zxytdb0b	344	196	development	development	NN
cord-347000-zxytdb0b	344	197	and	and	CC
cord-347000-zxytdb0b	344	198	antibiotic	antibiotic	JJ
cord-347000-zxytdb0b	344	199	susceptibility	susceptibility	NN
cord-347000-zxytdb0b	344	200	among	among	IN
cord-347000-zxytdb0b	344	201	Streptococcus	streptococcus	NN
cord-347000-zxytdb0b	344	202	pneumoniae	pneumoniae	NN
cord-347000-zxytdb0b	344	203	isolates	isolate	VBZ
cord-347000-zxytdb0b	344	204	from	from	IN
cord-347000-zxytdb0b	344	205	cystic	cystic	JJ
cord-347000-zxytdb0b	344	206	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	344	207	samples	sample	NNS
cord-347000-zxytdb0b	344	208	and	and	CC
cord-347000-zxytdb0b	344	209	blood	blood	NN
cord-347000-zxytdb0b	344	210	cultures	culture	NNS
cord-347000-zxytdb0b	345	1	Macrolide	macrolide	JJ
cord-347000-zxytdb0b	345	2	antibiotics	antibiotic	NNS
cord-347000-zxytdb0b	345	3	for	for	IN
cord-347000-zxytdb0b	345	4	cystic	cystic	JJ
cord-347000-zxytdb0b	345	5	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	345	6	Increased	increase	VBD
cord-347000-zxytdb0b	345	7	morbidity	morbidity	NN
cord-347000-zxytdb0b	345	8	associated	associate	VBN
cord-347000-zxytdb0b	345	9	with	with	IN
cord-347000-zxytdb0b	345	10	chronic	chronic	JJ
cord-347000-zxytdb0b	345	11	infection	infection	NN
cord-347000-zxytdb0b	345	12	by	by	IN
cord-347000-zxytdb0b	345	13	an	an	DT
cord-347000-zxytdb0b	345	14	epidemic	epidemic	NN
cord-347000-zxytdb0b	345	15	Pseudomonas	Pseudomonas	NNP
cord-347000-zxytdb0b	345	16	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	345	17	strain	strain	NN
cord-347000-zxytdb0b	345	18	in	in	IN
cord-347000-zxytdb0b	345	19	CF	CF	NNP
cord-347000-zxytdb0b	345	20	patients	patient	NNS
cord-347000-zxytdb0b	345	21	Spread	Spread	VBN
cord-347000-zxytdb0b	345	22	of	of	IN
cord-347000-zxytdb0b	345	23	a	a	DT
cord-347000-zxytdb0b	345	24	multiresistant	multiresistant	JJ
cord-347000-zxytdb0b	345	25	strain	strain	NN
cord-347000-zxytdb0b	345	26	of	of	IN
cord-347000-zxytdb0b	345	27	Pseudomonas	Pseudomonas	NNP
cord-347000-zxytdb0b	345	28	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	345	29	in	in	IN
cord-347000-zxytdb0b	346	1	an	an	DT
cord-347000-zxytdb0b	346	2	adult	adult	NN
cord-347000-zxytdb0b	346	3	cystic	cystic	JJ
cord-347000-zxytdb0b	346	4	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	346	5	clinic	clinic	NN
cord-347000-zxytdb0b	346	6	Widespread	widespread	JJ
cord-347000-zxytdb0b	346	7	pyocyanin	pyocyanin	NNP
cord-347000-zxytdb0b	347	1	over	over	IN
cord-347000-zxytdb0b	347	2	-	-	HYPH
cord-347000-zxytdb0b	347	3	production	production	NN
cord-347000-zxytdb0b	347	4	among	among	IN
cord-347000-zxytdb0b	347	5	isolates	isolate	NNS
cord-347000-zxytdb0b	347	6	of	of	IN
cord-347000-zxytdb0b	347	7	a	a	DT
cord-347000-zxytdb0b	347	8	cystic	cystic	JJ
cord-347000-zxytdb0b	347	9	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	347	10	epidemic	epidemic	NN
cord-347000-zxytdb0b	347	11	strain	strain	NN
cord-347000-zxytdb0b	347	12	Quorum	Quorum	NNP
cord-347000-zxytdb0b	347	13	sensing	sensing	NN
cord-347000-zxytdb0b	347	14	:	:	:
cord-347000-zxytdb0b	347	15	the	the	DT
cord-347000-zxytdb0b	347	16	power	power	NN
cord-347000-zxytdb0b	347	17	of	of	IN
cord-347000-zxytdb0b	347	18	cooperation	cooperation	NN
cord-347000-zxytdb0b	347	19	in	in	IN
cord-347000-zxytdb0b	347	20	the	the	DT
cord-347000-zxytdb0b	347	21	world	world	NN
cord-347000-zxytdb0b	347	22	of	of	IN
cord-347000-zxytdb0b	347	23	Pseudomonas	Pseudomonas	NNP
cord-347000-zxytdb0b	347	24	Highly	highly	RB
cord-347000-zxytdb0b	347	25	adherent	adherent	JJ
cord-347000-zxytdb0b	347	26	small	small	JJ
cord-347000-zxytdb0b	347	27	-	-	HYPH
cord-347000-zxytdb0b	347	28	colony	colony	NN
cord-347000-zxytdb0b	347	29	variants	variant	NNS
cord-347000-zxytdb0b	347	30	of	of	IN
cord-347000-zxytdb0b	347	31	Pseudomonas	Pseudomonas	NNP
cord-347000-zxytdb0b	347	32	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	347	33	in	in	IN
cord-347000-zxytdb0b	347	34	cystic	cystic	JJ
cord-347000-zxytdb0b	347	35	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	347	36	lung	lung	NN
cord-347000-zxytdb0b	347	37	infection	infection	NN
cord-347000-zxytdb0b	348	1	Phenotypic	phenotypic	JJ
cord-347000-zxytdb0b	348	2	variability	variability	NN
cord-347000-zxytdb0b	348	3	of	of	IN
cord-347000-zxytdb0b	348	4	Pseudomonas	Pseudomonas	NNP
cord-347000-zxytdb0b	348	5	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	348	6	in	in	IN
cord-347000-zxytdb0b	348	7	sputa	sputa	NN
cord-347000-zxytdb0b	348	8	from	from	IN
cord-347000-zxytdb0b	348	9	patients	patient	NNS
cord-347000-zxytdb0b	348	10	with	with	IN
cord-347000-zxytdb0b	348	11	acute	acute	JJ
cord-347000-zxytdb0b	348	12	infective	infective	JJ
cord-347000-zxytdb0b	348	13	exacerbation	exacerbation	NN
cord-347000-zxytdb0b	348	14	of	of	IN
cord-347000-zxytdb0b	348	15	cystic	cystic	JJ
cord-347000-zxytdb0b	348	16	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	348	17	and	and	CC
cord-347000-zxytdb0b	348	18	its	-PRON-	PRP$
cord-347000-zxytdb0b	348	19	impact	impact	NN
cord-347000-zxytdb0b	348	20	on	on	IN
cord-347000-zxytdb0b	348	21	the	the	DT
cord-347000-zxytdb0b	348	22	validity	validity	NN
cord-347000-zxytdb0b	348	23	of	of	IN
cord-347000-zxytdb0b	348	24	antimicrobial	antimicrobial	JJ
cord-347000-zxytdb0b	348	25	susceptibility	susceptibility	NN
cord-347000-zxytdb0b	348	26	testing	testing	NN
cord-347000-zxytdb0b	348	27	Recovery	Recovery	NNP
cord-347000-zxytdb0b	348	28	of	of	IN
cord-347000-zxytdb0b	348	29	antimicrobial	antimicrobial	JJ
cord-347000-zxytdb0b	348	30	-	-	HYPH
cord-347000-zxytdb0b	348	31	resistant	resistant	JJ
cord-347000-zxytdb0b	348	32	Pseudomonas	Pseudomonas	NNP
cord-347000-zxytdb0b	348	33	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	348	34	from	from	IN
cord-347000-zxytdb0b	348	35	sputa	sputa	NN
cord-347000-zxytdb0b	348	36	of	of	IN
cord-347000-zxytdb0b	348	37	cystic	cystic	JJ
cord-347000-zxytdb0b	348	38	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	348	39	patients	patient	NNS
cord-347000-zxytdb0b	348	40	by	by	IN
cord-347000-zxytdb0b	348	41	culture	culture	NN
cord-347000-zxytdb0b	348	42	on	on	IN
cord-347000-zxytdb0b	348	43	selective	selective	JJ
cord-347000-zxytdb0b	348	44	media	medium	NNS
cord-347000-zxytdb0b	348	45	Susceptibility	susceptibility	NN
cord-347000-zxytdb0b	348	46	testing	testing	NN
cord-347000-zxytdb0b	348	47	of	of	IN
cord-347000-zxytdb0b	348	48	Pseudomonas	Pseudomonas	NNP
cord-347000-zxytdb0b	348	49	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	348	50	isolates	isolate	NNS
cord-347000-zxytdb0b	348	51	and	and	CC
cord-347000-zxytdb0b	348	52	clinical	clinical	JJ
cord-347000-zxytdb0b	348	53	response	response	NN
cord-347000-zxytdb0b	348	54	to	to	IN
cord-347000-zxytdb0b	348	55	parenteral	parenteral	JJ
cord-347000-zxytdb0b	348	56	antibiotic	antibiotic	JJ
cord-347000-zxytdb0b	348	57	administration	administration	NN
cord-347000-zxytdb0b	348	58	:	:	:
cord-347000-zxytdb0b	348	59	lack	lack	NN
cord-347000-zxytdb0b	348	60	of	of	IN
cord-347000-zxytdb0b	348	61	association	association	NN
cord-347000-zxytdb0b	348	62	in	in	IN
cord-347000-zxytdb0b	348	63	cystic	cystic	JJ
cord-347000-zxytdb0b	348	64	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	348	65	Microbial	microbial	JJ
cord-347000-zxytdb0b	348	66	pathogenesis	pathogenesis	NN
cord-347000-zxytdb0b	348	67	in	in	IN
cord-347000-zxytdb0b	348	68	cystic	cystic	JJ
cord-347000-zxytdb0b	348	69	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	348	70	:	:	:
cord-347000-zxytdb0b	348	71	mucoid	mucoid	NNP
cord-347000-zxytdb0b	348	72	Pseudomonas	Pseudomonas	NNP
cord-347000-zxytdb0b	348	73	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	348	74	and	and	CC
cord-347000-zxytdb0b	348	75	Burkholderia	Burkholderia	NNP
cord-347000-zxytdb0b	348	76	cepacia	cepacia	NNP
cord-347000-zxytdb0b	348	77	Survey	Survey	NNP
cord-347000-zxytdb0b	348	78	of	of	IN
cord-347000-zxytdb0b	348	79	resistance	resistance	NN
cord-347000-zxytdb0b	348	80	of	of	IN
cord-347000-zxytdb0b	348	81	Pseudomonas	Pseudomonas	NNP
cord-347000-zxytdb0b	348	82	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	348	83	from	from	IN
cord-347000-zxytdb0b	348	84	UK	UK	NNP
cord-347000-zxytdb0b	348	85	patients	patient	NNS
cord-347000-zxytdb0b	348	86	with	with	IN
cord-347000-zxytdb0b	348	87	cystic	cystic	JJ
cord-347000-zxytdb0b	348	88	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	348	89	to	to	IN
cord-347000-zxytdb0b	348	90	six	six	CD
cord-347000-zxytdb0b	348	91	commonly	commonly	RB
cord-347000-zxytdb0b	348	92	prescribed	prescribe	VBN
cord-347000-zxytdb0b	348	93	antimicrobial	antimicrobial	JJ
cord-347000-zxytdb0b	348	94	agents	agent	NNS
cord-347000-zxytdb0b	348	95	Comparison	Comparison	NNP
cord-347000-zxytdb0b	348	96	of	of	IN
cord-347000-zxytdb0b	348	97	methodologies	methodology	NNS
cord-347000-zxytdb0b	348	98	for	for	IN
cord-347000-zxytdb0b	348	99	synergism	synergism	NN
cord-347000-zxytdb0b	348	100	testing	testing	NN
cord-347000-zxytdb0b	348	101	of	of	IN
cord-347000-zxytdb0b	348	102	drug	drug	NN
cord-347000-zxytdb0b	348	103	combinations	combination	NNS
cord-347000-zxytdb0b	348	104	against	against	IN
cord-347000-zxytdb0b	348	105	resistant	resistant	JJ
cord-347000-zxytdb0b	348	106	strains	strain	NNS
cord-347000-zxytdb0b	348	107	of	of	IN
cord-347000-zxytdb0b	348	108	Pseudomonas	Pseudomonas	NNP
cord-347000-zxytdb0b	348	109	aeruginosa	aeruginosa	NNP
cord-347000-zxytdb0b	348	110	Combination	Combination	NNP
cord-347000-zxytdb0b	348	111	antibiotic	antibiotic	JJ
cord-347000-zxytdb0b	348	112	susceptibility	susceptibility	NN
cord-347000-zxytdb0b	348	113	testing	testing	NN
cord-347000-zxytdb0b	348	114	to	to	TO
cord-347000-zxytdb0b	348	115	treat	treat	VB
cord-347000-zxytdb0b	348	116	exacerbations	exacerbation	NNS
cord-347000-zxytdb0b	348	117	of	of	IN
cord-347000-zxytdb0b	348	118	cystic	cystic	JJ
cord-347000-zxytdb0b	348	119	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	348	120	associated	associate	VBN
cord-347000-zxytdb0b	348	121	with	with	IN
cord-347000-zxytdb0b	348	122	multiresistant	multiresistant	JJ
cord-347000-zxytdb0b	348	123	bacteria	bacteria	NNS
cord-347000-zxytdb0b	348	124	:	:	:
cord-347000-zxytdb0b	348	125	a	a	DT
cord-347000-zxytdb0b	348	126	randomised	randomised	JJ
cord-347000-zxytdb0b	348	127	,	,	,
cord-347000-zxytdb0b	348	128	double	double	JJ
cord-347000-zxytdb0b	348	129	-	-	HYPH
cord-347000-zxytdb0b	348	130	blind	blind	JJ
cord-347000-zxytdb0b	348	131	,	,	,
cord-347000-zxytdb0b	348	132	controlled	control	VBN
cord-347000-zxytdb0b	348	133	clinical	clinical	JJ
cord-347000-zxytdb0b	348	134	trial	trial	NN
cord-347000-zxytdb0b	348	135	High	high	JJ
cord-347000-zxytdb0b	348	136	frequency	frequency	NN
cord-347000-zxytdb0b	348	137	of	of	IN
cord-347000-zxytdb0b	348	138	hypermutable	hypermutable	JJ
cord-347000-zxytdb0b	348	139	Pseudomonas	Pseudomonas	NNP
cord-347000-zxytdb0b	348	140	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	348	141	in	in	IN
cord-347000-zxytdb0b	348	142	cystic	cystic	JJ
cord-347000-zxytdb0b	348	143	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	348	144	lung	lung	NN
cord-347000-zxytdb0b	348	145	infection	infection	NN
cord-347000-zxytdb0b	349	1	Hypermutation	Hypermutation	NNP
cord-347000-zxytdb0b	349	2	is	be	VBZ
cord-347000-zxytdb0b	349	3	a	a	DT
cord-347000-zxytdb0b	349	4	key	key	JJ
cord-347000-zxytdb0b	349	5	factor	factor	NN
cord-347000-zxytdb0b	349	6	in	in	IN
cord-347000-zxytdb0b	349	7	development	development	NN
cord-347000-zxytdb0b	349	8	of	of	IN
cord-347000-zxytdb0b	349	9	multiple	multiple	JJ
cord-347000-zxytdb0b	349	10	-	-	HYPH
cord-347000-zxytdb0b	349	11	antimicrobial	antimicrobial	JJ
cord-347000-zxytdb0b	349	12	resistance	resistance	NN
cord-347000-zxytdb0b	349	13	in	in	IN
cord-347000-zxytdb0b	349	14	Pseudomonas	Pseudomonas	NNP
cord-347000-zxytdb0b	349	15	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	349	16	strains	strain	NNS
cord-347000-zxytdb0b	349	17	causing	cause	VBG
cord-347000-zxytdb0b	349	18	chronic	chronic	JJ
cord-347000-zxytdb0b	349	19	lung	lung	NN
cord-347000-zxytdb0b	349	20	infections	infection	NNS
cord-347000-zxytdb0b	349	21	Pseudomonas	Pseudomonas	NNP
cord-347000-zxytdb0b	349	22	aeruginosa	aeruginosa	VBZ
cord-347000-zxytdb0b	349	23	hypermutators	hypermutator	NNS
cord-347000-zxytdb0b	349	24	in	in	IN
cord-347000-zxytdb0b	349	25	cystic	cystic	JJ
cord-347000-zxytdb0b	349	26	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	349	27	Physiological	physiological	JJ
cord-347000-zxytdb0b	349	28	heterogeneity	heterogeneity	NN
cord-347000-zxytdb0b	349	29	in	in	IN
cord-347000-zxytdb0b	349	30	biofilms	biofilm	NNS
cord-347000-zxytdb0b	349	31	Clinically	clinically	RB
cord-347000-zxytdb0b	349	32	feasible	feasible	JJ
cord-347000-zxytdb0b	349	33	biofilm	biofilm	NN
cord-347000-zxytdb0b	349	34	susceptibility	susceptibility	NN
cord-347000-zxytdb0b	349	35	assay	assay	NN
cord-347000-zxytdb0b	349	36	for	for	IN
cord-347000-zxytdb0b	349	37	isolates	isolate	NNS
cord-347000-zxytdb0b	349	38	of	of	IN
cord-347000-zxytdb0b	349	39	Pseudomonas	Pseudomonas	NNP
cord-347000-zxytdb0b	349	40	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	349	41	from	from	IN
cord-347000-zxytdb0b	349	42	patients	patient	NNS
cord-347000-zxytdb0b	349	43	with	with	IN
cord-347000-zxytdb0b	349	44	cystic	cystic	JJ
cord-347000-zxytdb0b	349	45	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	349	46	Genetic	genetic	JJ
cord-347000-zxytdb0b	349	47	adaptation	adaptation	NN
cord-347000-zxytdb0b	349	48	by	by	IN
cord-347000-zxytdb0b	349	49	Pseudomonas	Pseudomonas	NNP
cord-347000-zxytdb0b	349	50	aeruginosa	aeruginosa	VBZ
cord-347000-zxytdb0b	349	51	to	to	IN
cord-347000-zxytdb0b	349	52	the	the	DT
cord-347000-zxytdb0b	349	53	airways	airways	NNPS
cord-347000-zxytdb0b	349	54	of	of	IN
cord-347000-zxytdb0b	349	55	cystic	cystic	JJ
cord-347000-zxytdb0b	349	56	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	349	57	patients	patient	NNS
cord-347000-zxytdb0b	349	58	Genetic	genetic	JJ
cord-347000-zxytdb0b	349	59	adaptation	adaptation	NN
cord-347000-zxytdb0b	349	60	of	of	IN
cord-347000-zxytdb0b	349	61	Pseudomonas	Pseudomonas	NNP
cord-347000-zxytdb0b	349	62	aeruginosa	aeruginosa	VBZ
cord-347000-zxytdb0b	349	63	to	to	IN
cord-347000-zxytdb0b	349	64	the	the	DT
cord-347000-zxytdb0b	349	65	airways	airways	NNPS
cord-347000-zxytdb0b	349	66	of	of	IN
cord-347000-zxytdb0b	349	67	cystic	cystic	JJ
cord-347000-zxytdb0b	349	68	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	349	69	patients	patient	NNS
cord-347000-zxytdb0b	349	70	is	be	VBZ
cord-347000-zxytdb0b	349	71	catalyzed	catalyze	VBN
cord-347000-zxytdb0b	349	72	by	by	IN
cord-347000-zxytdb0b	349	73	hypermutation	hypermutation	NN
cord-347000-zxytdb0b	349	74	Occurrence	occurrence	NN
cord-347000-zxytdb0b	349	75	of	of	IN
cord-347000-zxytdb0b	349	76	multiple	multiple	JJ
cord-347000-zxytdb0b	349	77	genomovars	genomovar	NNS
cord-347000-zxytdb0b	349	78	of	of	IN
cord-347000-zxytdb0b	349	79	Burkholderia	Burkholderia	NNP
cord-347000-zxytdb0b	349	80	cepacia	cepacia	NNP
cord-347000-zxytdb0b	349	81	in	in	IN
cord-347000-zxytdb0b	349	82	cystic	cystic	JJ
cord-347000-zxytdb0b	349	83	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	349	84	patients	patient	NNS
cord-347000-zxytdb0b	349	85	and	and	CC
cord-347000-zxytdb0b	349	86	proposal	proposal	NN
cord-347000-zxytdb0b	349	87	of	of	IN
cord-347000-zxytdb0b	349	88	Burkholderia	Burkholderia	NNP
cord-347000-zxytdb0b	349	89	multivorans	multivorans	NNP
cord-347000-zxytdb0b	349	90	sp	sp	NNP
cord-347000-zxytdb0b	349	91	.	.	.
cord-347000-zxytdb0b	350	1	nov	nov	NNP
cord-347000-zxytdb0b	350	2	Burkholderia	Burkholderia	NNP
cord-347000-zxytdb0b	350	3	latens	laten	VBZ
cord-347000-zxytdb0b	350	4	sp	sp	NN
cord-347000-zxytdb0b	350	5	.	.	.
cord-347000-zxytdb0b	351	1	nov	nov	NNP
cord-347000-zxytdb0b	351	2	.	.	.
cord-347000-zxytdb0b	352	1	,	,	,
cord-347000-zxytdb0b	352	2	Burkholderia	Burkholderia	NNP
cord-347000-zxytdb0b	352	3	diffusa	diffusa	NN
cord-347000-zxytdb0b	352	4	sp	sp	NN
cord-347000-zxytdb0b	352	5	.	.	.
cord-347000-zxytdb0b	353	1	nov	nov	NNP
cord-347000-zxytdb0b	353	2	.	.	.
cord-347000-zxytdb0b	354	1	,	,	,
cord-347000-zxytdb0b	354	2	Burkholderia	Burkholderia	NNP
cord-347000-zxytdb0b	354	3	arboris	arboris	RB
cord-347000-zxytdb0b	354	4	sp	sp	NN
cord-347000-zxytdb0b	354	5	.	.	.
cord-347000-zxytdb0b	355	1	nov	nov	NNP
cord-347000-zxytdb0b	355	2	.	.	.
cord-347000-zxytdb0b	356	1	,	,	,
cord-347000-zxytdb0b	356	2	Burkholderia	Burkholderia	NNP
cord-347000-zxytdb0b	356	3	seminalis	seminali	VBD
cord-347000-zxytdb0b	356	4	sp	sp	NNP
cord-347000-zxytdb0b	356	5	.	.	.
cord-347000-zxytdb0b	357	1	nov	nov	NNP
cord-347000-zxytdb0b	357	2	.	.	.
cord-347000-zxytdb0b	358	1	and	and	CC
cord-347000-zxytdb0b	358	2	Burkholderia	Burkholderia	NNP
cord-347000-zxytdb0b	358	3	metallica	metallica	NNP
cord-347000-zxytdb0b	358	4	sp	sp	NNP
cord-347000-zxytdb0b	358	5	.	.	.
cord-347000-zxytdb0b	359	1	nov	nov	NNP
cord-347000-zxytdb0b	359	2	.	.	.
cord-347000-zxytdb0b	360	1	,	,	,
cord-347000-zxytdb0b	360	2	novel	novel	JJ
cord-347000-zxytdb0b	360	3	species	specie	NNS
cord-347000-zxytdb0b	360	4	within	within	IN
cord-347000-zxytdb0b	360	5	the	the	DT
cord-347000-zxytdb0b	360	6	Burkholderia	Burkholderia	NNP
cord-347000-zxytdb0b	360	7	cepacia	cepacia	NNP
cord-347000-zxytdb0b	360	8	complex	complex	JJ
cord-347000-zxytdb0b	361	1	The	the	DT
cord-347000-zxytdb0b	361	2	multifarious	multifarious	JJ
cord-347000-zxytdb0b	361	3	,	,	,
cord-347000-zxytdb0b	361	4	multireplicon	multireplicon	NNP
cord-347000-zxytdb0b	361	5	Burkholderia	Burkholderia	NNP
cord-347000-zxytdb0b	361	6	cepacia	cepacia	NNP
cord-347000-zxytdb0b	361	7	complex	complex	JJ
cord-347000-zxytdb0b	362	1	Evolving	evolve	VBG
cord-347000-zxytdb0b	362	2	epidemiology	epidemiology	NN
cord-347000-zxytdb0b	362	3	of	of	IN
cord-347000-zxytdb0b	362	4	Pseudomonas	Pseudomonas	NNP
cord-347000-zxytdb0b	362	5	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	362	6	and	and	CC
cord-347000-zxytdb0b	362	7	the	the	DT
cord-347000-zxytdb0b	362	8	Burkholderia	Burkholderia	NNP
cord-347000-zxytdb0b	362	9	cepacia	cepacia	NNP
cord-347000-zxytdb0b	362	10	complex	complex	NN
cord-347000-zxytdb0b	362	11	in	in	IN
cord-347000-zxytdb0b	362	12	cystic	cystic	JJ
cord-347000-zxytdb0b	362	13	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	362	14	lung	lung	NN
cord-347000-zxytdb0b	362	15	infection	infection	NN
cord-347000-zxytdb0b	362	16	Impact	Impact	NNP
cord-347000-zxytdb0b	362	17	of	of	IN
cord-347000-zxytdb0b	362	18	Burkholderia	Burkholderia	NNP
cord-347000-zxytdb0b	362	19	dolosa	dolosa	NNP
cord-347000-zxytdb0b	362	20	on	on	IN
cord-347000-zxytdb0b	362	21	lung	lung	NN
cord-347000-zxytdb0b	362	22	function	function	NN
cord-347000-zxytdb0b	362	23	and	and	CC
cord-347000-zxytdb0b	362	24	survival	survival	NN
cord-347000-zxytdb0b	362	25	in	in	IN
cord-347000-zxytdb0b	363	1	cystic	cystic	JJ
cord-347000-zxytdb0b	363	2	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	363	3	Infection	Infection	NNP
cord-347000-zxytdb0b	363	4	with	with	IN
cord-347000-zxytdb0b	363	5	Burkholderia	Burkholderia	NNP
cord-347000-zxytdb0b	363	6	cepacia	cepacia	NNP
cord-347000-zxytdb0b	363	7	complex	complex	JJ
cord-347000-zxytdb0b	363	8	bacteria	bacteria	NNS
cord-347000-zxytdb0b	363	9	and	and	CC
cord-347000-zxytdb0b	363	10	pulmonary	pulmonary	JJ
cord-347000-zxytdb0b	363	11	exacerbations	exacerbation	NNS
cord-347000-zxytdb0b	363	12	of	of	IN
cord-347000-zxytdb0b	363	13	cystic	cystic	JJ
cord-347000-zxytdb0b	363	14	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	363	15	Cystic	cystic	JJ
cord-347000-zxytdb0b	363	16	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	363	17	and	and	CC
cord-347000-zxytdb0b	363	18	Burkholderia	Burkholderia	NNP
cord-347000-zxytdb0b	363	19	pseudomallei	pseudomallei	VBD
cord-347000-zxytdb0b	363	20	infection	infection	NN
cord-347000-zxytdb0b	363	21	:	:	:
cord-347000-zxytdb0b	364	1	an	an	DT
cord-347000-zxytdb0b	364	2	emerging	emerge	VBG
cord-347000-zxytdb0b	364	3	problem	problem	NN
cord-347000-zxytdb0b	364	4	?	?	.
cord-347000-zxytdb0b	365	1	Association	Association	NNP
cord-347000-zxytdb0b	365	2	between	between	IN
cord-347000-zxytdb0b	365	3	Stenotrophomonas	Stenotrophomonas	NNP
cord-347000-zxytdb0b	365	4	maltophilia	maltophilia	NNP
cord-347000-zxytdb0b	365	5	and	and	CC
cord-347000-zxytdb0b	365	6	lung	lung	NN
cord-347000-zxytdb0b	365	7	function	function	NN
cord-347000-zxytdb0b	365	8	in	in	IN
cord-347000-zxytdb0b	365	9	cystic	cystic	JJ
cord-347000-zxytdb0b	365	10	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	366	1	Achromobacter	Achromobacter	NNP
cord-347000-zxytdb0b	366	2	xylosoxidans	xylosoxidans	NNP
cord-347000-zxytdb0b	366	3	in	in	IN
cord-347000-zxytdb0b	366	4	cystic	cystic	JJ
cord-347000-zxytdb0b	366	5	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	366	6	:	:	:
cord-347000-zxytdb0b	367	1	prevalence	prevalence	NN
cord-347000-zxytdb0b	367	2	and	and	CC
cord-347000-zxytdb0b	367	3	clinical	clinical	JJ
cord-347000-zxytdb0b	367	4	relevance	relevance	NN
cord-347000-zxytdb0b	368	1	Epidemic	epidemic	NN
cord-347000-zxytdb0b	368	2	spread	spread	NN
cord-347000-zxytdb0b	368	3	of	of	IN
cord-347000-zxytdb0b	368	4	Pandoraea	Pandoraea	NNP
cord-347000-zxytdb0b	368	5	apista	apista	NN
cord-347000-zxytdb0b	368	6	,	,	,
cord-347000-zxytdb0b	368	7	a	a	DT
cord-347000-zxytdb0b	368	8	new	new	JJ
cord-347000-zxytdb0b	368	9	pathogen	pathogen	NN
cord-347000-zxytdb0b	368	10	causing	cause	VBG
cord-347000-zxytdb0b	368	11	severe	severe	JJ
cord-347000-zxytdb0b	368	12	lung	lung	NN
cord-347000-zxytdb0b	368	13	disease	disease	NN
cord-347000-zxytdb0b	368	14	in	in	IN
cord-347000-zxytdb0b	368	15	cystic	cystic	JJ
cord-347000-zxytdb0b	368	16	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	368	17	patients	patient	NNS
cord-347000-zxytdb0b	368	18	Characterization	Characterization	NNP
cord-347000-zxytdb0b	368	19	of	of	IN
cord-347000-zxytdb0b	368	20	unusual	unusual	JJ
cord-347000-zxytdb0b	368	21	bacteria	bacteria	NNS
cord-347000-zxytdb0b	368	22	isolated	isolate	VBN
cord-347000-zxytdb0b	368	23	from	from	IN
cord-347000-zxytdb0b	368	24	respiratory	respiratory	JJ
cord-347000-zxytdb0b	368	25	secretions	secretion	NNS
cord-347000-zxytdb0b	368	26	of	of	IN
cord-347000-zxytdb0b	368	27	cystic	cystic	JJ
cord-347000-zxytdb0b	368	28	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	368	29	patients	patient	NNS
cord-347000-zxytdb0b	368	30	and	and	CC
cord-347000-zxytdb0b	368	31	description	description	NN
cord-347000-zxytdb0b	368	32	of	of	IN
cord-347000-zxytdb0b	368	33	Inquilinus	Inquilinus	NNP
cord-347000-zxytdb0b	368	34	limosus	limosus	NNP
cord-347000-zxytdb0b	368	35	gen	gen	NNP
cord-347000-zxytdb0b	368	36	.	.	NNP
cord-347000-zxytdb0b	368	37	nov	nov	NNP
cord-347000-zxytdb0b	368	38	.	.	NNP
cord-347000-zxytdb0b	368	39	,	,	,
cord-347000-zxytdb0b	368	40	sp	sp	NNP
cord-347000-zxytdb0b	368	41	.	.	.
cord-347000-zxytdb0b	369	1	nov	nov	NNP
cord-347000-zxytdb0b	369	2	Superiority	Superiority	NNP
cord-347000-zxytdb0b	369	3	of	of	IN
cord-347000-zxytdb0b	369	4	molecular	molecular	JJ
cord-347000-zxytdb0b	369	5	techniques	technique	NNS
cord-347000-zxytdb0b	369	6	for	for	IN
cord-347000-zxytdb0b	369	7	identification	identification	NN
cord-347000-zxytdb0b	369	8	of	of	IN
cord-347000-zxytdb0b	369	9	gram	gram	NN
cord-347000-zxytdb0b	369	10	-	-	HYPH
cord-347000-zxytdb0b	369	11	negative	negative	JJ
cord-347000-zxytdb0b	369	12	,	,	,
cord-347000-zxytdb0b	369	13	oxidase	oxidase	NN
cord-347000-zxytdb0b	369	14	-	-	HYPH
cord-347000-zxytdb0b	369	15	positive	positive	JJ
cord-347000-zxytdb0b	369	16	rods	rod	NNS
cord-347000-zxytdb0b	369	17	,	,	,
cord-347000-zxytdb0b	369	18	including	include	VBG
cord-347000-zxytdb0b	369	19	morphologically	morphologically	RB
cord-347000-zxytdb0b	369	20	nontypical	nontypical	JJ
cord-347000-zxytdb0b	369	21	Pseudomonas	Pseudomonas	NNP
cord-347000-zxytdb0b	369	22	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	369	23	,	,	,
cord-347000-zxytdb0b	369	24	from	from	IN
cord-347000-zxytdb0b	369	25	patients	patient	NNS
cord-347000-zxytdb0b	369	26	with	with	IN
cord-347000-zxytdb0b	369	27	cystic	cystic	JJ
cord-347000-zxytdb0b	369	28	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	369	29	Atypical	atypical	JJ
cord-347000-zxytdb0b	369	30	mycobacterial	mycobacterial	JJ
cord-347000-zxytdb0b	369	31	infection	infection	NN
cord-347000-zxytdb0b	369	32	in	in	IN
cord-347000-zxytdb0b	369	33	patients	patient	NNS
cord-347000-zxytdb0b	369	34	with	with	IN
cord-347000-zxytdb0b	369	35	cystic	cystic	JJ
cord-347000-zxytdb0b	369	36	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	369	37	:	:	:
cord-347000-zxytdb0b	369	38	update	update	VB
cord-347000-zxytdb0b	369	39	on	on	IN
cord-347000-zxytdb0b	369	40	clinical	clinical	JJ
cord-347000-zxytdb0b	369	41	microbiology	microbiology	NN
cord-347000-zxytdb0b	369	42	methods	method	NNS
cord-347000-zxytdb0b	369	43	Nontuberculous	nontuberculous	JJ
cord-347000-zxytdb0b	369	44	mycobacteria	mycobacterium	NNS
cord-347000-zxytdb0b	369	45	.	.	.
cord-347000-zxytdb0b	370	1	I	-PRON-	PRP
cord-347000-zxytdb0b	370	2	:	:	:
cord-347000-zxytdb0b	370	3	multicenter	multicenter	JJ
cord-347000-zxytdb0b	370	4	prevalence	prevalence	NN
cord-347000-zxytdb0b	370	5	study	study	NN
cord-347000-zxytdb0b	370	6	in	in	IN
cord-347000-zxytdb0b	370	7	cystic	cystic	JJ
cord-347000-zxytdb0b	370	8	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	370	9	Age	Age	NNP
cord-347000-zxytdb0b	370	10	-	-	HYPH
cord-347000-zxytdb0b	370	11	related	relate	VBN
cord-347000-zxytdb0b	370	12	prevalence	prevalence	NN
cord-347000-zxytdb0b	370	13	and	and	CC
cord-347000-zxytdb0b	370	14	distribution	distribution	NN
cord-347000-zxytdb0b	370	15	of	of	IN
cord-347000-zxytdb0b	370	16	nontuberculous	nontuberculous	JJ
cord-347000-zxytdb0b	370	17	mycobacterial	mycobacterial	JJ
cord-347000-zxytdb0b	370	18	species	specie	NNS
cord-347000-zxytdb0b	370	19	among	among	IN
cord-347000-zxytdb0b	370	20	patients	patient	NNS
cord-347000-zxytdb0b	370	21	with	with	IN
cord-347000-zxytdb0b	370	22	cystic	cystic	JJ
cord-347000-zxytdb0b	370	23	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	370	24	Hypervirulence	Hypervirulence	NNP
cord-347000-zxytdb0b	370	25	of	of	IN
cord-347000-zxytdb0b	370	26	a	a	DT
cord-347000-zxytdb0b	370	27	rough	rough	JJ
cord-347000-zxytdb0b	370	28	variant	variant	NN
cord-347000-zxytdb0b	370	29	of	of	IN
cord-347000-zxytdb0b	370	30	the	the	DT
cord-347000-zxytdb0b	370	31	Mycobacterium	Mycobacterium	NNP
cord-347000-zxytdb0b	370	32	abscessus	abscessus	NN
cord-347000-zxytdb0b	370	33	type	type	NN
cord-347000-zxytdb0b	370	34	strain	strain	VBP
cord-347000-zxytdb0b	370	35	Spontaneous	spontaneous	JJ
cord-347000-zxytdb0b	370	36	reversion	reversion	NN
cord-347000-zxytdb0b	370	37	of	of	IN
cord-347000-zxytdb0b	370	38	Mycobacterium	Mycobacterium	NNP
cord-347000-zxytdb0b	370	39	abscessus	abscessus	NN
cord-347000-zxytdb0b	370	40	from	from	IN
cord-347000-zxytdb0b	370	41	a	a	DT
cord-347000-zxytdb0b	370	42	smooth	smooth	JJ
cord-347000-zxytdb0b	370	43	to	to	IN
cord-347000-zxytdb0b	370	44	a	a	DT
cord-347000-zxytdb0b	370	45	rough	rough	JJ
cord-347000-zxytdb0b	370	46	morphotype	morphotype	NN
cord-347000-zxytdb0b	370	47	is	be	VBZ
cord-347000-zxytdb0b	370	48	associated	associate	VBN
cord-347000-zxytdb0b	370	49	with	with	IN
cord-347000-zxytdb0b	370	50	reduced	reduce	VBN
cord-347000-zxytdb0b	370	51	expression	expression	NN
cord-347000-zxytdb0b	370	52	of	of	IN
cord-347000-zxytdb0b	370	53	glycopeptidolipid	glycopeptidolipid	NN
cord-347000-zxytdb0b	370	54	and	and	CC
cord-347000-zxytdb0b	370	55	reacquisition	reacquisition	NN
cord-347000-zxytdb0b	370	56	of	of	IN
cord-347000-zxytdb0b	370	57	an	an	DT
cord-347000-zxytdb0b	370	58	invasive	invasive	JJ
cord-347000-zxytdb0b	370	59	phenotype	phenotype	NN
cord-347000-zxytdb0b	370	60	Differential	differential	NN
cord-347000-zxytdb0b	370	61	antibiotic	antibiotic	JJ
cord-347000-zxytdb0b	370	62	susceptibility	susceptibility	NN
cord-347000-zxytdb0b	370	63	of	of	IN
cord-347000-zxytdb0b	370	64	Mycobacterium	Mycobacterium	NNP
cord-347000-zxytdb0b	370	65	abscessus	abscessus	NN
cord-347000-zxytdb0b	370	66	variants	variant	NNS
cord-347000-zxytdb0b	370	67	in	in	IN
cord-347000-zxytdb0b	370	68	biofilms	biofilm	NNS
cord-347000-zxytdb0b	370	69	and	and	CC
cord-347000-zxytdb0b	370	70	macrophages	macrophage	NNS
cord-347000-zxytdb0b	370	71	compared	compare	VBN
cord-347000-zxytdb0b	370	72	to	to	IN
cord-347000-zxytdb0b	370	73	that	that	DT
cord-347000-zxytdb0b	370	74	of	of	IN
cord-347000-zxytdb0b	370	75	planktonic	planktonic	JJ
cord-347000-zxytdb0b	370	76	bacteria	bacteria	NNS
cord-347000-zxytdb0b	371	1	An	an	DT
cord-347000-zxytdb0b	371	2	official	official	JJ
cord-347000-zxytdb0b	371	3	ATS	ATS	NNP
cord-347000-zxytdb0b	371	4	/	/	SYM
cord-347000-zxytdb0b	371	5	IDSA	IDSA	NNP
cord-347000-zxytdb0b	371	6	statement	statement	NN
cord-347000-zxytdb0b	371	7	:	:	:
cord-347000-zxytdb0b	371	8	diagnosis	diagnosis	NN
cord-347000-zxytdb0b	371	9	,	,	,
cord-347000-zxytdb0b	371	10	treatment	treatment	NN
cord-347000-zxytdb0b	371	11	,	,	,
cord-347000-zxytdb0b	371	12	and	and	CC
cord-347000-zxytdb0b	371	13	prevention	prevention	NN
cord-347000-zxytdb0b	371	14	of	of	IN
cord-347000-zxytdb0b	371	15	nontuberculous	nontuberculous	JJ
cord-347000-zxytdb0b	371	16	mycobacterial	mycobacterial	NNP
cord-347000-zxytdb0b	371	17	diseases	disease	NNS
cord-347000-zxytdb0b	372	1	Allergic	allergic	JJ
cord-347000-zxytdb0b	372	2	bronchopulmonary	bronchopulmonary	JJ
cord-347000-zxytdb0b	372	3	aspergillosis	aspergillosis	NNP
cord-347000-zxytdb0b	372	4	in	in	IN
cord-347000-zxytdb0b	372	5	cystic	cystic	JJ
cord-347000-zxytdb0b	372	6	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	372	7	-	-	HYPH
cord-347000-zxytdb0b	372	8	state	state	NN
cord-347000-zxytdb0b	372	9	of	of	IN
cord-347000-zxytdb0b	372	10	the	the	DT
cord-347000-zxytdb0b	372	11	art	art	NN
cord-347000-zxytdb0b	372	12	Aspergillus	aspergillus	NN
cord-347000-zxytdb0b	372	13	bronchitis	bronchitis	NN
cord-347000-zxytdb0b	372	14	in	in	IN
cord-347000-zxytdb0b	372	15	cystic	cystic	JJ
cord-347000-zxytdb0b	372	16	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	373	1	Clinical	clinical	JJ
cord-347000-zxytdb0b	373	2	significance	significance	NN
cord-347000-zxytdb0b	373	3	of	of	IN
cord-347000-zxytdb0b	373	4	Scedosporium	Scedosporium	NNP
cord-347000-zxytdb0b	373	5	apiospermum	apiospermum	NN
cord-347000-zxytdb0b	373	6	in	in	IN
cord-347000-zxytdb0b	373	7	patients	patient	NNS
cord-347000-zxytdb0b	373	8	with	with	IN
cord-347000-zxytdb0b	373	9	cystic	cystic	JJ
cord-347000-zxytdb0b	373	10	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	373	11	Modulation	modulation	NN
cord-347000-zxytdb0b	373	12	of	of	IN
cord-347000-zxytdb0b	373	13	Pseudomonas	Pseudomonas	NNP
cord-347000-zxytdb0b	373	14	aeruginosa	aeruginosa	NN
cord-347000-zxytdb0b	373	15	gene	gene	NN
cord-347000-zxytdb0b	373	16	expression	expression	NN
cord-347000-zxytdb0b	373	17	by	by	IN
cord-347000-zxytdb0b	373	18	host	host	NN
cord-347000-zxytdb0b	373	19	microflora	microflora	NN
cord-347000-zxytdb0b	373	20	through	through	IN
cord-347000-zxytdb0b	373	21	interspecies	interspecie	NNS
cord-347000-zxytdb0b	373	22	communication	communication	NN
cord-347000-zxytdb0b	373	23	Detection	detection	NN
cord-347000-zxytdb0b	373	24	of	of	IN
cord-347000-zxytdb0b	373	25	anaerobic	anaerobic	JJ
cord-347000-zxytdb0b	373	26	bacteria	bacteria	NNS
cord-347000-zxytdb0b	373	27	in	in	IN
cord-347000-zxytdb0b	373	28	high	high	JJ
cord-347000-zxytdb0b	373	29	numbers	number	NNS
cord-347000-zxytdb0b	373	30	in	in	IN
cord-347000-zxytdb0b	373	31	sputum	sputum	NN
cord-347000-zxytdb0b	373	32	from	from	IN
cord-347000-zxytdb0b	373	33	patients	patient	NNS
cord-347000-zxytdb0b	373	34	with	with	IN
cord-347000-zxytdb0b	373	35	cystic	cystic	JJ
cord-347000-zxytdb0b	373	36	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	373	37	Characterization	characterization	NN
cord-347000-zxytdb0b	373	38	of	of	IN
cord-347000-zxytdb0b	373	39	bacterial	bacterial	JJ
cord-347000-zxytdb0b	373	40	community	community	NN
cord-347000-zxytdb0b	373	41	diversity	diversity	NN
cord-347000-zxytdb0b	373	42	in	in	IN
cord-347000-zxytdb0b	373	43	cystic	cystic	JJ
cord-347000-zxytdb0b	373	44	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	373	45	lung	lung	NN
cord-347000-zxytdb0b	373	46	infections	infection	NNS
cord-347000-zxytdb0b	373	47	by	by	IN
cord-347000-zxytdb0b	373	48	use	use	NN
cord-347000-zxytdb0b	373	49	of	of	IN
cord-347000-zxytdb0b	373	50	16s	16	NNS
cord-347000-zxytdb0b	373	51	ribosomal	ribosomal	JJ
cord-347000-zxytdb0b	373	52	DNA	dna	NN
cord-347000-zxytdb0b	373	53	terminal	terminal	NN
cord-347000-zxytdb0b	373	54	restriction	restriction	NN
cord-347000-zxytdb0b	373	55	fragment	fragment	NN
cord-347000-zxytdb0b	373	56	length	length	NN
cord-347000-zxytdb0b	373	57	polymorphism	polymorphism	NN
cord-347000-zxytdb0b	373	58	profiling	profile	VBG
cord-347000-zxytdb0b	373	59	Impact	impact	NN
cord-347000-zxytdb0b	373	60	of	of	IN
cord-347000-zxytdb0b	373	61	respiratory	respiratory	JJ
cord-347000-zxytdb0b	373	62	viral	viral	JJ
cord-347000-zxytdb0b	373	63	infections	infection	NNS
cord-347000-zxytdb0b	373	64	on	on	IN
cord-347000-zxytdb0b	373	65	cystic	cystic	JJ
cord-347000-zxytdb0b	373	66	fibrosis	fibrosis	NN
cord-347000-zxytdb0b	373	67	COPD	COPD	NNP
cord-347000-zxytdb0b	373	68	exacerbations	exacerbation	NNS
cord-347000-zxytdb0b	373	69	:	:	:
cord-347000-zxytdb0b	374	1	defining	define	VBG
cord-347000-zxytdb0b	374	2	their	-PRON-	PRP$
cord-347000-zxytdb0b	374	3	cause	cause	NN
cord-347000-zxytdb0b	374	4	and	and	CC
cord-347000-zxytdb0b	374	5	prevention	prevention	NN
cord-347000-zxytdb0b	374	6	Pan	pan	JJ
cord-347000-zxytdb0b	374	7	-	-	JJ
cord-347000-zxytdb0b	374	8	viral	viral	JJ
cord-347000-zxytdb0b	374	9	screening	screening	NN
cord-347000-zxytdb0b	374	10	of	of	IN
cord-347000-zxytdb0b	374	11	respiratory	respiratory	JJ
cord-347000-zxytdb0b	374	12	tract	tract	NN
cord-347000-zxytdb0b	374	13	infections	infection	NNS
cord-347000-zxytdb0b	374	14	in	in	IN
cord-347000-zxytdb0b	374	15	adults	adult	NNS
cord-347000-zxytdb0b	374	16	with	with	IN
cord-347000-zxytdb0b	374	17	and	and	CC
cord-347000-zxytdb0b	374	18	without	without	IN
cord-347000-zxytdb0b	374	19	asthma	asthma	NN
cord-347000-zxytdb0b	374	20	reveals	reveal	VBZ
cord-347000-zxytdb0b	374	21	unexpected	unexpected	JJ
cord-347000-zxytdb0b	374	22	human	human	JJ
cord-347000-zxytdb0b	374	23	coronavirus	coronavirus	NN
cord-347000-zxytdb0b	374	24	and	and	CC
cord-347000-zxytdb0b	374	25	human	human	JJ
cord-347000-zxytdb0b	374	26	rhinovirus	rhinovirus	NN
cord-347000-zxytdb0b	374	27	diversity	diversity	NN