id sid tid token lemma pos cord-301276-eer1l8vg 1 1 key key JJ cord-301276-eer1l8vg 1 2 : : : cord-301276-eer1l8vg 1 3 cord-301276-eer1l8vg cord-301276-eer1l8vg CD cord-301276-eer1l8vg 1 4 authors author NNS cord-301276-eer1l8vg 1 5 : : : cord-301276-eer1l8vg 1 6 Sehrawat Sehrawat NNP cord-301276-eer1l8vg 1 7 , , , cord-301276-eer1l8vg 1 8 Sharvan Sharvan NNP cord-301276-eer1l8vg 1 9 ; ; : cord-301276-eer1l8vg 1 10 Rouse rouse VB cord-301276-eer1l8vg 1 11 , , , cord-301276-eer1l8vg 1 12 Barry Barry NNP cord-301276-eer1l8vg 1 13 T. T. NNP cord-301276-eer1l8vg 2 1 title title NN cord-301276-eer1l8vg 2 2 : : : cord-301276-eer1l8vg 2 3 Opinion opinion NN cord-301276-eer1l8vg 2 4 : : : cord-301276-eer1l8vg 3 1 Does do VBZ cord-301276-eer1l8vg 3 2 the the DT cord-301276-eer1l8vg 3 3 hygiene hygiene NN cord-301276-eer1l8vg 3 4 hypothesis hypothesis NN cord-301276-eer1l8vg 3 5 apply apply VB cord-301276-eer1l8vg 3 6 to to IN cord-301276-eer1l8vg 3 7 COVID-19 covid-19 JJ cord-301276-eer1l8vg 3 8 susceptibility susceptibility NN cord-301276-eer1l8vg 3 9 ? ? . cord-301276-eer1l8vg 4 1 date date NN cord-301276-eer1l8vg 4 2 : : : cord-301276-eer1l8vg 4 3 2020 2020 CD cord-301276-eer1l8vg 4 4 - - HYPH cord-301276-eer1l8vg 4 5 07 07 CD cord-301276-eer1l8vg 4 6 - - HYPH cord-301276-eer1l8vg 4 7 09 09 CD cord-301276-eer1l8vg 4 8 journal journal NN cord-301276-eer1l8vg 4 9 : : : cord-301276-eer1l8vg 5 1 Microbes microbe NNS cord-301276-eer1l8vg 5 2 Infect infect VBP cord-301276-eer1l8vg 5 3 DOI doi NN cord-301276-eer1l8vg 5 4 : : : cord-301276-eer1l8vg 5 5 10.1016 10.1016 CD cord-301276-eer1l8vg 6 1 /j.micinf.2020.07.002 /j.micinf.2020.07.002 NFP cord-301276-eer1l8vg 6 2 sha sha NNP cord-301276-eer1l8vg 6 3 : : : cord-301276-eer1l8vg 6 4 ff7fe3ff53a39f9e0a5335a3622bf37e30a2e082 ff7fe3ff53a39f9e0a5335a3622bf37e30a2e082 NFP cord-301276-eer1l8vg 6 5 doc_id doc_id CD cord-301276-eer1l8vg 6 6 : : : cord-301276-eer1l8vg 7 1 301276 301276 CD cord-301276-eer1l8vg 7 2 cord_uid cord_uid NN cord-301276-eer1l8vg 7 3 : : : cord-301276-eer1l8vg 8 1 eer1l8vg eer1l8vg RB cord-301276-eer1l8vg 9 1 In in IN cord-301276-eer1l8vg 9 2 this this DT cord-301276-eer1l8vg 9 3 commentary commentary NN cord-301276-eer1l8vg 9 4 we -PRON- PRP cord-301276-eer1l8vg 9 5 argue argue VBP cord-301276-eer1l8vg 9 6 that that IN cord-301276-eer1l8vg 9 7 the the DT cord-301276-eer1l8vg 9 8 hygiene hygiene NN cord-301276-eer1l8vg 9 9 hypothesis hypothesis NN cord-301276-eer1l8vg 9 10 may may MD cord-301276-eer1l8vg 9 11 apply apply VB cord-301276-eer1l8vg 9 12 to to IN cord-301276-eer1l8vg 9 13 COVID-19 covid-19 JJ cord-301276-eer1l8vg 9 14 susceptibility susceptibility NN cord-301276-eer1l8vg 9 15 and and CC cord-301276-eer1l8vg 9 16 also also RB cord-301276-eer1l8vg 9 17 that that DT cord-301276-eer1l8vg 9 18 residence residence NN cord-301276-eer1l8vg 9 19 in in IN cord-301276-eer1l8vg 9 20 low low JJ cord-301276-eer1l8vg 9 21 hygienic hygienic JJ cord-301276-eer1l8vg 9 22 conditions condition NNS cord-301276-eer1l8vg 9 23 acts act VBZ cord-301276-eer1l8vg 9 24 to to TO cord-301276-eer1l8vg 9 25 train train VB cord-301276-eer1l8vg 9 26 innate innate JJ cord-301276-eer1l8vg 9 27 immune immune JJ cord-301276-eer1l8vg 9 28 defenses defense NNS cord-301276-eer1l8vg 9 29 to to TO cord-301276-eer1l8vg 9 30 minimize minimize VB cord-301276-eer1l8vg 9 31 the the DT cord-301276-eer1l8vg 9 32 severity severity NN cord-301276-eer1l8vg 9 33 of of IN cord-301276-eer1l8vg 9 34 infection infection NN cord-301276-eer1l8vg 9 35 . . . cord-301276-eer1l8vg 10 1 We -PRON- PRP cord-301276-eer1l8vg 10 2 advocate advocate VBP cord-301276-eer1l8vg 10 3 that that IN cord-301276-eer1l8vg 10 4 approaches approach NNS cord-301276-eer1l8vg 10 5 , , , cord-301276-eer1l8vg 10 6 which which WDT cord-301276-eer1l8vg 10 7 elevate elevate VBP cord-301276-eer1l8vg 10 8 innate innate JJ cord-301276-eer1l8vg 10 9 immune immune JJ cord-301276-eer1l8vg 10 10 functions function NNS cord-301276-eer1l8vg 10 11 , , , cord-301276-eer1l8vg 10 12 should should MD cord-301276-eer1l8vg 10 13 be be VB cord-301276-eer1l8vg 10 14 used use VBN cord-301276-eer1l8vg 10 15 to to TO cord-301276-eer1l8vg 10 16 minimize minimize VB cord-301276-eer1l8vg 10 17 the the DT cord-301276-eer1l8vg 10 18 consequences consequence NNS cord-301276-eer1l8vg 10 19 of of IN cord-301276-eer1l8vg 10 20 COVID-19 covid-19 JJ cord-301276-eer1l8vg 10 21 infection infection NN cord-301276-eer1l8vg 10 22 at at IN cord-301276-eer1l8vg 10 23 least least JJS cord-301276-eer1l8vg 10 24 until until IN cord-301276-eer1l8vg 10 25 effective effective JJ cord-301276-eer1l8vg 10 26 vaccines vaccine NNS cord-301276-eer1l8vg 10 27 and and CC cord-301276-eer1l8vg 10 28 antiviral antiviral JJ cord-301276-eer1l8vg 10 29 therapies therapy NNS cord-301276-eer1l8vg 10 30 are be VBP cord-301276-eer1l8vg 10 31 developed develop VBN cord-301276-eer1l8vg 10 32 . . . cord-301276-eer1l8vg 11 1 In in IN cord-301276-eer1l8vg 11 2 this this DT cord-301276-eer1l8vg 11 3 commentary commentary NN cord-301276-eer1l8vg 11 4 we -PRON- PRP cord-301276-eer1l8vg 11 5 argue argue VBP cord-301276-eer1l8vg 11 6 that that IN cord-301276-eer1l8vg 11 7 the the DT cord-301276-eer1l8vg 11 8 hygiene hygiene NN cord-301276-eer1l8vg 11 9 hypothesis hypothesis NN cord-301276-eer1l8vg 11 10 may may MD cord-301276-eer1l8vg 11 11 apply apply VB cord-301276-eer1l8vg 11 12 to to IN cord-301276-eer1l8vg 11 13 susceptibility susceptibility NN cord-301276-eer1l8vg 11 14 and and CC cord-301276-eer1l8vg 11 15 also also RB cord-301276-eer1l8vg 11 16 that that DT cord-301276-eer1l8vg 11 17 residence residence NN cord-301276-eer1l8vg 11 18 in in IN cord-301276-eer1l8vg 11 19 low low JJ cord-301276-eer1l8vg 11 20 hygienic hygienic JJ cord-301276-eer1l8vg 11 21 conditions condition NNS cord-301276-eer1l8vg 11 22 acts act VBZ cord-301276-eer1l8vg 11 23 to to TO cord-301276-eer1l8vg 11 24 train train VB cord-301276-eer1l8vg 11 25 innate innate JJ cord-301276-eer1l8vg 11 26 immune immune JJ cord-301276-eer1l8vg 11 27 defenses defense NNS cord-301276-eer1l8vg 11 28 to to TO cord-301276-eer1l8vg 11 29 minimize minimize VB cord-301276-eer1l8vg 11 30 the the DT cord-301276-eer1l8vg 11 31 severity severity NN cord-301276-eer1l8vg 11 32 of of IN cord-301276-eer1l8vg 11 33 infection infection NN cord-301276-eer1l8vg 11 34 . . . cord-301276-eer1l8vg 12 1 We -PRON- PRP cord-301276-eer1l8vg 12 2 advocate advocate VBP cord-301276-eer1l8vg 12 3 that that IN cord-301276-eer1l8vg 12 4 approaches approach NNS cord-301276-eer1l8vg 12 5 , , , cord-301276-eer1l8vg 12 6 which which WDT cord-301276-eer1l8vg 12 7 elevate elevate VBP cord-301276-eer1l8vg 12 8 innate innate JJ cord-301276-eer1l8vg 12 9 immune immune JJ cord-301276-eer1l8vg 12 10 functions function NNS cord-301276-eer1l8vg 12 11 , , , cord-301276-eer1l8vg 12 12 should should MD cord-301276-eer1l8vg 12 13 be be VB cord-301276-eer1l8vg 12 14 used use VBN cord-301276-eer1l8vg 12 15 to to TO cord-301276-eer1l8vg 12 16 minimize minimize VB cord-301276-eer1l8vg 12 17 the the DT cord-301276-eer1l8vg 12 18 consequences consequence NNS cord-301276-eer1l8vg 12 19 of of IN cord-301276-eer1l8vg 12 20 COVID-19 covid-19 JJ cord-301276-eer1l8vg 12 21 infection infection NN cord-301276-eer1l8vg 12 22 at at IN cord-301276-eer1l8vg 12 23 least least JJS cord-301276-eer1l8vg 12 24 until until IN cord-301276-eer1l8vg 12 25 effective effective JJ cord-301276-eer1l8vg 12 26 vaccines vaccine NNS cord-301276-eer1l8vg 12 27 and and CC cord-301276-eer1l8vg 12 28 antiviral antiviral JJ cord-301276-eer1l8vg 12 29 therapies therapy NNS cord-301276-eer1l8vg 12 30 are be VBP cord-301276-eer1l8vg 12 31 developed develop VBN cord-301276-eer1l8vg 12 32 . . . cord-301276-eer1l8vg 13 1 Currently currently RB cord-301276-eer1l8vg 13 2 , , , cord-301276-eer1l8vg 13 3 the the DT cord-301276-eer1l8vg 13 4 world world NN cord-301276-eer1l8vg 13 5 is be VBZ cord-301276-eer1l8vg 13 6 experiencing experience VBG cord-301276-eer1l8vg 13 7 a a DT cord-301276-eer1l8vg 13 8 new new JJ cord-301276-eer1l8vg 13 9 coronavirus coronavirus NN cord-301276-eer1l8vg 13 10 pandemic pandemic NN cord-301276-eer1l8vg 13 11 with with IN cord-301276-eer1l8vg 13 12 no no DT cord-301276-eer1l8vg 13 13 solution solution NN cord-301276-eer1l8vg 13 14 or or CC cord-301276-eer1l8vg 13 15 end end NN cord-301276-eer1l8vg 13 16 in in IN cord-301276-eer1l8vg 13 17 sight sight NN cord-301276-eer1l8vg 13 18 . . . cord-301276-eer1l8vg 14 1 In in IN cord-301276-eer1l8vg 14 2 some some DT cord-301276-eer1l8vg 14 3 societies society NNS cord-301276-eer1l8vg 14 4 > > NFP cord-301276-eer1l8vg 14 5 10 10 CD cord-301276-eer1l8vg 14 6 % % NN cord-301276-eer1l8vg 14 7 of of IN cord-301276-eer1l8vg 14 8 the the DT cord-301276-eer1l8vg 14 9 population population NN cord-301276-eer1l8vg 14 10 has have VBZ cord-301276-eer1l8vg 14 11 been be VBN cord-301276-eer1l8vg 14 12 exposed expose VBN cord-301276-eer1l8vg 14 13 to to IN cord-301276-eer1l8vg 14 14 Severe severe JJ cord-301276-eer1l8vg 14 15 Acute acute JJ cord-301276-eer1l8vg 14 16 Respiratory Respiratory NNP cord-301276-eer1l8vg 14 17 Syndrome Syndrome NNP cord-301276-eer1l8vg 14 18 - - HYPH cord-301276-eer1l8vg 14 19 Coronavirus Coronavirus NNP cord-301276-eer1l8vg 14 20 2 2 CD cord-301276-eer1l8vg 14 21 ( ( -LRB- cord-301276-eer1l8vg 14 22 referred refer VBN cord-301276-eer1l8vg 14 23 to to IN cord-301276-eer1l8vg 14 24 as as IN cord-301276-eer1l8vg 14 25 COVID- covid- NN cord-301276-eer1l8vg 14 26 19 19 CD cord-301276-eer1l8vg 14 27 ) ) -RRB- cord-301276-eer1l8vg 14 28 , , , cord-301276-eer1l8vg 14 29 but but CC cord-301276-eer1l8vg 14 30 epidemiologists epidemiologist NNS cord-301276-eer1l8vg 14 31 inform inform VBP cord-301276-eer1l8vg 14 32 us -PRON- PRP cord-301276-eer1l8vg 14 33 that that IN cord-301276-eer1l8vg 14 34 60 60 CD cord-301276-eer1l8vg 14 35 - - SYM cord-301276-eer1l8vg 14 36 70 70 CD cord-301276-eer1l8vg 14 37 % % NN cord-301276-eer1l8vg 14 38 need need NN cord-301276-eer1l8vg 14 39 to to TO cord-301276-eer1l8vg 14 40 experience experience VB cord-301276-eer1l8vg 14 41 the the DT cord-301276-eer1l8vg 14 42 infection infection NN cord-301276-eer1l8vg 14 43 if if IN cord-301276-eer1l8vg 14 44 protective protective JJ cord-301276-eer1l8vg 14 45 herd herd NN cord-301276-eer1l8vg 14 46 immunity immunity NN cord-301276-eer1l8vg 14 47 is be VBZ cord-301276-eer1l8vg 14 48 to to TO cord-301276-eer1l8vg 14 49 be be VB cord-301276-eer1l8vg 14 50 established establish VBN cord-301276-eer1l8vg 14 51 ( ( -LRB- cord-301276-eer1l8vg 14 52 1 1 CD cord-301276-eer1l8vg 14 53 ) ) -RRB- cord-301276-eer1l8vg 14 54 . . . cord-301276-eer1l8vg 15 1 We -PRON- PRP cord-301276-eer1l8vg 15 2 could could MD cord-301276-eer1l8vg 15 3 minimize minimize VB cord-301276-eer1l8vg 15 4 the the DT cord-301276-eer1l8vg 15 5 need need NN cord-301276-eer1l8vg 15 6 for for IN cord-301276-eer1l8vg 15 7 natural natural JJ cord-301276-eer1l8vg 15 8 herd herd NN cord-301276-eer1l8vg 15 9 immunity immunity NN cord-301276-eer1l8vg 15 10 by by IN cord-301276-eer1l8vg 15 11 using use VBG cord-301276-eer1l8vg 15 12 prophylactic prophylactic JJ cord-301276-eer1l8vg 15 13 vaccines vaccine NNS cord-301276-eer1l8vg 15 14 , , , cord-301276-eer1l8vg 15 15 but but CC cord-301276-eer1l8vg 15 16 the the DT cord-301276-eer1l8vg 15 17 prospects prospect NNS cord-301276-eer1l8vg 15 18 of of IN cord-301276-eer1l8vg 15 19 developing develop VBG cord-301276-eer1l8vg 15 20 vaccines vaccine NNS cord-301276-eer1l8vg 15 21 that that WDT cord-301276-eer1l8vg 15 22 confer confer VBP cord-301276-eer1l8vg 15 23 long long JJ cord-301276-eer1l8vg 15 24 term term NN cord-301276-eer1l8vg 15 25 effective effective JJ cord-301276-eer1l8vg 15 26 immunity immunity NN cord-301276-eer1l8vg 15 27 against against IN cord-301276-eer1l8vg 15 28 COVID-19 COVID-19 NNP cord-301276-eer1l8vg 15 29 is be VBZ cord-301276-eer1l8vg 15 30 uncertain uncertain JJ cord-301276-eer1l8vg 15 31 . . . cord-301276-eer1l8vg 16 1 This this DT cord-301276-eer1l8vg 16 2 new new JJ cord-301276-eer1l8vg 16 3 coronavirus coronavirus NN cord-301276-eer1l8vg 16 4 is be VBZ cord-301276-eer1l8vg 16 5 highly highly RB cord-301276-eer1l8vg 16 6 infectious infectious JJ cord-301276-eer1l8vg 16 7 with with IN cord-301276-eer1l8vg 16 8 the the DT cord-301276-eer1l8vg 16 9 outcome outcome NN cord-301276-eer1l8vg 16 10 of of IN cord-301276-eer1l8vg 16 11 infection infection NN cord-301276-eer1l8vg 16 12 extremely extremely RB cord-301276-eer1l8vg 16 13 variable variable JJ cord-301276-eer1l8vg 16 14 ranging range VBG cord-301276-eer1l8vg 16 15 from from IN cord-301276-eer1l8vg 16 16 asymptomatic asymptomatic JJ cord-301276-eer1l8vg 16 17 to to IN cord-301276-eer1l8vg 16 18 fatal fatal JJ cord-301276-eer1l8vg 16 19 . . . cord-301276-eer1l8vg 17 1 However however RB cord-301276-eer1l8vg 17 2 , , , cord-301276-eer1l8vg 17 3 the the DT cord-301276-eer1l8vg 17 4 spectrum spectrum NN cord-301276-eer1l8vg 17 5 of of IN cord-301276-eer1l8vg 17 6 disease disease NN cord-301276-eer1l8vg 17 7 in in IN cord-301276-eer1l8vg 17 8 different different JJ cord-301276-eer1l8vg 17 9 societies society NNS cord-301276-eer1l8vg 17 10 varies vary VBZ cord-301276-eer1l8vg 17 11 markedly markedly RB cord-301276-eer1l8vg 17 12 for for IN cord-301276-eer1l8vg 17 13 reasons reason NNS cord-301276-eer1l8vg 17 14 as as IN cord-301276-eer1l8vg 17 15 yet yet RB cord-301276-eer1l8vg 17 16 not not RB cord-301276-eer1l8vg 17 17 fully fully RB cord-301276-eer1l8vg 17 18 understood understand VBN cord-301276-eer1l8vg 17 19 . . . cord-301276-eer1l8vg 18 1 For for IN cord-301276-eer1l8vg 18 2 instance instance NN cord-301276-eer1l8vg 18 3 , , , cord-301276-eer1l8vg 18 4 in in IN cord-301276-eer1l8vg 18 5 some some DT cord-301276-eer1l8vg 18 6 developed develop VBN cord-301276-eer1l8vg 18 7 countries country NNS cord-301276-eer1l8vg 18 8 , , , cord-301276-eer1l8vg 18 9 the the DT cord-301276-eer1l8vg 18 10 reported report VBN cord-301276-eer1l8vg 18 11 fatality fatality NN cord-301276-eer1l8vg 18 12 rate rate NN cord-301276-eer1l8vg 18 13 is be VBZ cord-301276-eer1l8vg 18 14 far far RB cord-301276-eer1l8vg 18 15 higher high JJR cord-301276-eer1l8vg 18 16 than than IN cord-301276-eer1l8vg 18 17 in in IN cord-301276-eer1l8vg 18 18 others other NNS cord-301276-eer1l8vg 18 19 . . . cord-301276-eer1l8vg 19 1 Also also RB cord-301276-eer1l8vg 19 2 evidence evidence NN cord-301276-eer1l8vg 19 3 shows show VBZ cord-301276-eer1l8vg 19 4 that that IN cord-301276-eer1l8vg 19 5 patients patient NNS cord-301276-eer1l8vg 19 6 infected infect VBN cord-301276-eer1l8vg 19 7 in in IN cord-301276-eer1l8vg 19 8 low low JJ cord-301276-eer1l8vg 19 9 socioeconomic socioeconomic JJ cord-301276-eer1l8vg 19 10 conditions condition NNS cord-301276-eer1l8vg 19 11 suffer suffer VBP cord-301276-eer1l8vg 19 12 low low JJ cord-301276-eer1l8vg 19 13 rates rate NNS cord-301276-eer1l8vg 19 14 of of IN cord-301276-eer1l8vg 19 15 severe severe JJ cord-301276-eer1l8vg 19 16 and and CC cord-301276-eer1l8vg 19 17 lethal lethal JJ cord-301276-eer1l8vg 19 18 infection infection NN cord-301276-eer1l8vg 19 19 compared compare VBN cord-301276-eer1l8vg 19 20 to to IN cord-301276-eer1l8vg 19 21 those those DT cord-301276-eer1l8vg 19 22 raised raise VBN cord-301276-eer1l8vg 19 23 in in IN cord-301276-eer1l8vg 19 24 more more JJR cord-301276-eer1l8vg 19 25 hygienic hygienic JJ cord-301276-eer1l8vg 19 26 circumstances circumstance NNS cord-301276-eer1l8vg 19 27 ( ( -LRB- cord-301276-eer1l8vg 19 28 2 2 CD cord-301276-eer1l8vg 19 29 ) ) -RRB- cord-301276-eer1l8vg 19 30 . . . cord-301276-eer1l8vg 20 1 All all DT cord-301276-eer1l8vg 20 2 infections infection NNS cord-301276-eer1l8vg 20 3 have have VBP cord-301276-eer1l8vg 20 4 variable variable JJ cord-301276-eer1l8vg 20 5 consequences consequence NNS cord-301276-eer1l8vg 20 6 and and CC cord-301276-eer1l8vg 20 7 others other NNS cord-301276-eer1l8vg 20 8 and and CC cord-301276-eer1l8vg 20 9 we -PRON- PRP cord-301276-eer1l8vg 20 10 have have VBP cord-301276-eer1l8vg 20 11 discussed discuss VBN cord-301276-eer1l8vg 20 12 the the DT cord-301276-eer1l8vg 20 13 many many JJ cord-301276-eer1l8vg 20 14 factors factor NNS cord-301276-eer1l8vg 20 15 that that WDT cord-301276-eer1l8vg 20 16 influence influence VBP cord-301276-eer1l8vg 20 17 the the DT cord-301276-eer1l8vg 20 18 outcome outcome NN cord-301276-eer1l8vg 20 19 of of IN cord-301276-eer1l8vg 20 20 infection infection NN cord-301276-eer1l8vg 20 21 with with IN cord-301276-eer1l8vg 20 22 a a DT cord-301276-eer1l8vg 20 23 virus virus NN cord-301276-eer1l8vg 20 24 ( ( -LRB- cord-301276-eer1l8vg 20 25 3 3 LS cord-301276-eer1l8vg 20 26 ) ) -RRB- cord-301276-eer1l8vg 20 27 ( ( -LRB- cord-301276-eer1l8vg 20 28 4 4 LS cord-301276-eer1l8vg 20 29 ) ) -RRB- cord-301276-eer1l8vg 20 30 ( ( -LRB- cord-301276-eer1l8vg 20 31 5 5 CD cord-301276-eer1l8vg 20 32 ) ) -RRB- cord-301276-eer1l8vg 20 33 . . . cord-301276-eer1l8vg 21 1 These these DT cord-301276-eer1l8vg 21 2 variables variable NNS cord-301276-eer1l8vg 21 3 include include VBP cord-301276-eer1l8vg 21 4 age age NN cord-301276-eer1l8vg 21 5 when when WRB cord-301276-eer1l8vg 21 6 infected infect VBN cord-301276-eer1l8vg 21 7 , , , cord-301276-eer1l8vg 21 8 dose dose NN cord-301276-eer1l8vg 21 9 and and CC cord-301276-eer1l8vg 21 10 nature nature NN cord-301276-eer1l8vg 21 11 of of IN cord-301276-eer1l8vg 21 12 infection infection NN cord-301276-eer1l8vg 21 13 , , , cord-301276-eer1l8vg 21 14 presence presence NN cord-301276-eer1l8vg 21 15 of of IN cord-301276-eer1l8vg 21 16 co co NNS cord-301276-eer1l8vg 21 17 - - NNS cord-301276-eer1l8vg 21 18 morbidities morbidity NNS cord-301276-eer1l8vg 21 19 when when WRB cord-301276-eer1l8vg 21 20 infected infect VBN cord-301276-eer1l8vg 21 21 such such JJ cord-301276-eer1l8vg 21 22 as as IN cord-301276-eer1l8vg 21 23 immune immune JJ cord-301276-eer1l8vg 21 24 suppression suppression NN cord-301276-eer1l8vg 21 25 , , , cord-301276-eer1l8vg 21 26 metabolic metabolic JJ cord-301276-eer1l8vg 21 27 disease disease NN cord-301276-eer1l8vg 21 28 and and CC cord-301276-eer1l8vg 21 29 cancer cancer NN cord-301276-eer1l8vg 21 30 , , , cord-301276-eer1l8vg 21 31 genetic genetic JJ cord-301276-eer1l8vg 21 32 and and CC cord-301276-eer1l8vg 21 33 epigenetic epigenetic JJ cord-301276-eer1l8vg 21 34 variables variable NNS cord-301276-eer1l8vg 21 35 , , , cord-301276-eer1l8vg 21 36 composition composition NN cord-301276-eer1l8vg 21 37 of of IN cord-301276-eer1l8vg 21 38 the the DT cord-301276-eer1l8vg 21 39 microbiome microbiome NN cord-301276-eer1l8vg 21 40 in in IN cord-301276-eer1l8vg 21 41 different different JJ cord-301276-eer1l8vg 21 42 locations location NNS cord-301276-eer1l8vg 21 43 as as RB cord-301276-eer1l8vg 21 44 well well RB cord-301276-eer1l8vg 21 45 as as IN cord-301276-eer1l8vg 21 46 past past JJ cord-301276-eer1l8vg 21 47 infection infection NN cord-301276-eer1l8vg 21 48 and and CC cord-301276-eer1l8vg 21 49 environmental environmental JJ cord-301276-eer1l8vg 21 50 experiences experience NNS cord-301276-eer1l8vg 21 51 . . . cord-301276-eer1l8vg 22 1 It -PRON- PRP cord-301276-eer1l8vg 22 2 is be VBZ cord-301276-eer1l8vg 22 3 relevant relevant JJ cord-301276-eer1l8vg 22 4 to to TO cord-301276-eer1l8vg 22 5 identify identify VB cord-301276-eer1l8vg 22 6 how how WRB cord-301276-eer1l8vg 22 7 these these DT cord-301276-eer1l8vg 22 8 various various JJ cord-301276-eer1l8vg 22 9 factors factor NNS cord-301276-eer1l8vg 22 10 come come VBP cord-301276-eer1l8vg 22 11 into into IN cord-301276-eer1l8vg 22 12 play play NN cord-301276-eer1l8vg 22 13 during during IN cord-301276-eer1l8vg 22 14 COVID-19 covid-19 JJ cord-301276-eer1l8vg 22 15 infection infection NN cord-301276-eer1l8vg 22 16 since since IN cord-301276-eer1l8vg 22 17 some some DT cord-301276-eer1l8vg 22 18 are be VBP cord-301276-eer1l8vg 22 19 subject subject JJ cord-301276-eer1l8vg 22 20 to to IN cord-301276-eer1l8vg 22 21 manipulation manipulation NN cord-301276-eer1l8vg 22 22 by by IN cord-301276-eer1l8vg 22 23 therapies therapy NNS cord-301276-eer1l8vg 22 24 that that WDT cord-301276-eer1l8vg 22 25 could could MD cord-301276-eer1l8vg 22 26 lower lower VB cord-301276-eer1l8vg 22 27 the the DT cord-301276-eer1l8vg 22 28 prospect prospect NN cord-301276-eer1l8vg 22 29 of of IN cord-301276-eer1l8vg 22 30 severe severe JJ cord-301276-eer1l8vg 22 31 disease disease NN cord-301276-eer1l8vg 22 32 . . . cord-301276-eer1l8vg 23 1 One one CD cord-301276-eer1l8vg 23 2 susceptibility susceptibility NN cord-301276-eer1l8vg 23 3 issue issue NN cord-301276-eer1l8vg 23 4 that that WDT cord-301276-eer1l8vg 23 5 has have VBZ cord-301276-eer1l8vg 23 6 received receive VBN cord-301276-eer1l8vg 23 7 minimal minimal JJ cord-301276-eer1l8vg 23 8 consideration consideration NN cord-301276-eer1l8vg 23 9 is be VBZ cord-301276-eer1l8vg 23 10 the the DT cord-301276-eer1l8vg 23 11 immune immune JJ cord-301276-eer1l8vg 23 12 status status NN cord-301276-eer1l8vg 23 13 established establish VBN cord-301276-eer1l8vg 23 14 as as IN cord-301276-eer1l8vg 23 15 a a DT cord-301276-eer1l8vg 23 16 consequence consequence NN cord-301276-eer1l8vg 23 17 of of IN cord-301276-eer1l8vg 23 18 past past JJ cord-301276-eer1l8vg 23 19 environmental environmental JJ cord-301276-eer1l8vg 23 20 and and CC cord-301276-eer1l8vg 23 21 microbial microbial JJ cord-301276-eer1l8vg 23 22 experiences experience NNS cord-301276-eer1l8vg 23 23 particularly particularly RB cord-301276-eer1l8vg 23 24 early early RB cord-301276-eer1l8vg 23 25 in in IN cord-301276-eer1l8vg 23 26 life life NN cord-301276-eer1l8vg 23 27 . . . cord-301276-eer1l8vg 24 1 In in IN cord-301276-eer1l8vg 24 2 the the DT cord-301276-eer1l8vg 24 3 early early JJ cord-301276-eer1l8vg 24 4 90s 90 NNS cord-301276-eer1l8vg 24 5 , , , cord-301276-eer1l8vg 24 6 the the DT cord-301276-eer1l8vg 24 7 so so RB cord-301276-eer1l8vg 24 8 - - HYPH cord-301276-eer1l8vg 24 9 called call VBN cord-301276-eer1l8vg 24 10 hygiene hygiene NN cord-301276-eer1l8vg 24 11 hypothesis hypothesis NN cord-301276-eer1l8vg 24 12 was be VBD cord-301276-eer1l8vg 24 13 formulated formulate VBN cord-301276-eer1l8vg 24 14 to to TO cord-301276-eer1l8vg 24 15 explain explain VB cord-301276-eer1l8vg 24 16 the the DT cord-301276-eer1l8vg 24 17 rising rise VBG cord-301276-eer1l8vg 24 18 incidence incidence NN cord-301276-eer1l8vg 24 19 of of IN cord-301276-eer1l8vg 24 20 diseases disease NNS cord-301276-eer1l8vg 24 21 such such JJ cord-301276-eer1l8vg 24 22 as as IN cord-301276-eer1l8vg 24 23 allergy allergy NN cord-301276-eer1l8vg 24 24 and and CC cord-301276-eer1l8vg 24 25 autoimmune autoimmune JJ cord-301276-eer1l8vg 24 26 diseases disease NNS cord-301276-eer1l8vg 24 27 occurring occur VBG cord-301276-eer1l8vg 24 28 in in IN cord-301276-eer1l8vg 24 29 the the DT cord-301276-eer1l8vg 24 30 developed develop VBN cord-301276-eer1l8vg 24 31 world world NN cord-301276-eer1l8vg 24 32 ( ( -LRB- cord-301276-eer1l8vg 24 33 6 6 CD cord-301276-eer1l8vg 24 34 , , , cord-301276-eer1l8vg 24 35 7 7 CD cord-301276-eer1l8vg 24 36 ) ) -RRB- cord-301276-eer1l8vg 24 37 . . . cord-301276-eer1l8vg 25 1 The the DT cord-301276-eer1l8vg 25 2 hypothesis hypothesis NN cord-301276-eer1l8vg 25 3 advocated advocate VBD cord-301276-eer1l8vg 25 4 that that IN cord-301276-eer1l8vg 25 5 children child NNS cord-301276-eer1l8vg 25 6 exposed expose VBN cord-301276-eer1l8vg 25 7 to to IN cord-301276-eer1l8vg 25 8 certain certain JJ cord-301276-eer1l8vg 25 9 environments environment NNS cord-301276-eer1l8vg 25 10 such such JJ cord-301276-eer1l8vg 25 11 as as IN cord-301276-eer1l8vg 25 12 farms farm NNS cord-301276-eer1l8vg 25 13 , , , cord-301276-eer1l8vg 25 14 domestic domestic JJ cord-301276-eer1l8vg 25 15 pets pet NNS cord-301276-eer1l8vg 25 16 and and CC cord-301276-eer1l8vg 25 17 exposure exposure NN cord-301276-eer1l8vg 25 18 to to IN cord-301276-eer1l8vg 25 19 enteric enteric JJ cord-301276-eer1l8vg 25 20 parasites parasite NNS cord-301276-eer1l8vg 25 21 were be VBD cord-301276-eer1l8vg 25 22 less less RBR cord-301276-eer1l8vg 25 23 likely likely JJ cord-301276-eer1l8vg 25 24 to to TO cord-301276-eer1l8vg 25 25 develop develop VB cord-301276-eer1l8vg 25 26 allergies allergy NNS cord-301276-eer1l8vg 25 27 and and CC cord-301276-eer1l8vg 25 28 some some DT cord-301276-eer1l8vg 25 29 autoimmune autoimmune JJ cord-301276-eer1l8vg 25 30 diseases disease NNS cord-301276-eer1l8vg 25 31 than than IN cord-301276-eer1l8vg 25 32 those those DT cord-301276-eer1l8vg 25 33 who who WP cord-301276-eer1l8vg 25 34 experienced experience VBD cord-301276-eer1l8vg 25 35 a a DT cord-301276-eer1l8vg 25 36 more more RBR cord-301276-eer1l8vg 25 37 hygienic hygienic JJ cord-301276-eer1l8vg 25 38 upbringing upbringing NN cord-301276-eer1l8vg 25 39 . . . cord-301276-eer1l8vg 26 1 Indeed indeed RB cord-301276-eer1l8vg 26 2 , , , cord-301276-eer1l8vg 26 3 at at IN cord-301276-eer1l8vg 26 4 least least JJS cord-301276-eer1l8vg 26 5 in in IN cord-301276-eer1l8vg 26 6 some some DT cord-301276-eer1l8vg 26 7 western western JJ cord-301276-eer1l8vg 26 8 societies society NNS cord-301276-eer1l8vg 26 9 well well RB cord-301276-eer1l8vg 26 10 before before IN cord-301276-eer1l8vg 26 11 COVID-19 COVID-19 NNP cord-301276-eer1l8vg 26 12 , , , cord-301276-eer1l8vg 26 13 the the DT cord-301276-eer1l8vg 26 14 extensive extensive JJ cord-301276-eer1l8vg 26 15 use use NN cord-301276-eer1l8vg 26 16 of of IN cord-301276-eer1l8vg 26 17 hand hand NN cord-301276-eer1l8vg 26 18 sanitizers sanitizer NNS cord-301276-eer1l8vg 26 19 and and CC cord-301276-eer1l8vg 26 20 frequent frequent JJ cord-301276-eer1l8vg 26 21 hand hand NN cord-301276-eer1l8vg 26 22 washings washing NNS cord-301276-eer1l8vg 26 23 were be VBD cord-301276-eer1l8vg 26 24 encouraged encourage VBN cord-301276-eer1l8vg 26 25 in in IN cord-301276-eer1l8vg 26 26 growing grow VBG cord-301276-eer1l8vg 26 27 children child NNS cord-301276-eer1l8vg 26 28 . . . cord-301276-eer1l8vg 27 1 Added add VBN cord-301276-eer1l8vg 27 2 to to IN cord-301276-eer1l8vg 27 3 this this DT cord-301276-eer1l8vg 27 4 heightened heightened JJ cord-301276-eer1l8vg 27 5 concern concern NN cord-301276-eer1l8vg 27 6 for for IN cord-301276-eer1l8vg 27 7 intense intense JJ cord-301276-eer1l8vg 27 8 hygienic hygienic JJ cord-301276-eer1l8vg 27 9 practices practice NNS cord-301276-eer1l8vg 27 10 has have VBZ cord-301276-eer1l8vg 27 11 been be VBN cord-301276-eer1l8vg 27 12 the the DT cord-301276-eer1l8vg 27 13 frequent frequent JJ cord-301276-eer1l8vg 27 14 exposure exposure NN cord-301276-eer1l8vg 27 15 of of IN cord-301276-eer1l8vg 27 16 children child NNS cord-301276-eer1l8vg 27 17 to to IN cord-301276-eer1l8vg 27 18 antibiotics antibiotic NNS cord-301276-eer1l8vg 27 19 to to TO cord-301276-eer1l8vg 27 20 ablate ablate VB cord-301276-eer1l8vg 27 21 potential potential JJ cord-301276-eer1l8vg 27 22 problems problem NNS cord-301276-eer1l8vg 27 23 before before IN cord-301276-eer1l8vg 27 24 they -PRON- PRP cord-301276-eer1l8vg 27 25 develop develop VBP cord-301276-eer1l8vg 27 26 into into IN cord-301276-eer1l8vg 27 27 clinical clinical JJ cord-301276-eer1l8vg 27 28 problems problem NNS cord-301276-eer1l8vg 27 29 that that WDT cord-301276-eer1l8vg 27 30 most most RBS cord-301276-eer1l8vg 27 31 often often RB cord-301276-eer1l8vg 27 32 amount amount VBP cord-301276-eer1l8vg 27 33 to to IN cord-301276-eer1l8vg 27 34 temporary temporary JJ cord-301276-eer1l8vg 27 35 inconveniences inconvenience NNS cord-301276-eer1l8vg 27 36 . . . cord-301276-eer1l8vg 28 1 The the DT cord-301276-eer1l8vg 28 2 unintended unintended JJ cord-301276-eer1l8vg 28 3 consequence consequence NN cord-301276-eer1l8vg 28 4 of of IN cord-301276-eer1l8vg 28 5 these these DT cord-301276-eer1l8vg 28 6 hyper hyper JJ cord-301276-eer1l8vg 28 7 - - JJ cord-301276-eer1l8vg 28 8 hygienic hygienic JJ cord-301276-eer1l8vg 28 9 regimens regimen NNS cord-301276-eer1l8vg 28 10 was be VBD cord-301276-eer1l8vg 28 11 to to TO cord-301276-eer1l8vg 28 12 change change VB cord-301276-eer1l8vg 28 13 the the DT cord-301276-eer1l8vg 28 14 basic basic JJ cord-301276-eer1l8vg 28 15 status status NN cord-301276-eer1l8vg 28 16 of of IN cord-301276-eer1l8vg 28 17 non non JJ cord-301276-eer1l8vg 28 18 - - JJ cord-301276-eer1l8vg 28 19 specific specific JJ cord-301276-eer1l8vg 28 20 immunity immunity NN cord-301276-eer1l8vg 28 21 , , , cord-301276-eer1l8vg 28 22 perhaps perhaps RB cord-301276-eer1l8vg 28 23 in in IN cord-301276-eer1l8vg 28 24 part part NN cord-301276-eer1l8vg 28 25 a a DT cord-301276-eer1l8vg 28 26 result result NN cord-301276-eer1l8vg 28 27 of of IN cord-301276-eer1l8vg 28 28 a a DT cord-301276-eer1l8vg 28 29 change change NN cord-301276-eer1l8vg 28 30 in in IN cord-301276-eer1l8vg 28 31 the the DT cord-301276-eer1l8vg 28 32 balance balance NN cord-301276-eer1l8vg 28 33 of of IN cord-301276-eer1l8vg 28 34 commensal commensal JJ cord-301276-eer1l8vg 28 35 microorganisms microorganism NNS cord-301276-eer1l8vg 28 36 in in IN cord-301276-eer1l8vg 28 37 the the DT cord-301276-eer1l8vg 28 38 gastrointestinal gastrointestinal JJ cord-301276-eer1l8vg 28 39 tract tract NN cord-301276-eer1l8vg 28 40 , , , cord-301276-eer1l8vg 28 41 skin skin NN cord-301276-eer1l8vg 28 42 and and CC cord-301276-eer1l8vg 28 43 other other JJ cord-301276-eer1l8vg 28 44 surface surface NN cord-301276-eer1l8vg 28 45 locations location NNS cord-301276-eer1l8vg 28 46 ( ( -LRB- cord-301276-eer1l8vg 28 47 8) 8) NNP cord-301276-eer1l8vg 28 48 . . . cord-301276-eer1l8vg 29 1 The the DT cord-301276-eer1l8vg 29 2 hygiene hygiene NN cord-301276-eer1l8vg 29 3 hypothesis hypothesis NN cord-301276-eer1l8vg 29 4 has have VBZ cord-301276-eer1l8vg 29 5 satisfactorily satisfactorily RB cord-301276-eer1l8vg 29 6 explained explain VBN cord-301276-eer1l8vg 29 7 the the DT cord-301276-eer1l8vg 29 8 increased increase VBN cord-301276-eer1l8vg 29 9 frequency frequency NN cord-301276-eer1l8vg 29 10 of of IN cord-301276-eer1l8vg 29 11 some some DT cord-301276-eer1l8vg 29 12 disease disease NN cord-301276-eer1l8vg 29 13 syndromes syndrome NNS cord-301276-eer1l8vg 29 14 , , , cord-301276-eer1l8vg 29 15 but but CC cord-301276-eer1l8vg 29 16 could could MD cord-301276-eer1l8vg 29 17 it -PRON- PRP cord-301276-eer1l8vg 29 18 also also RB cord-301276-eer1l8vg 29 19 explain explain VB cord-301276-eer1l8vg 29 20 why why WRB cord-301276-eer1l8vg 29 21 some some DT cord-301276-eer1l8vg 29 22 individuals individual NNS cord-301276-eer1l8vg 29 23 are be VBP cord-301276-eer1l8vg 29 24 more more RBR cord-301276-eer1l8vg 29 25 susceptible susceptible JJ cord-301276-eer1l8vg 29 26 to to IN cord-301276-eer1l8vg 29 27 the the DT cord-301276-eer1l8vg 29 28 severe severe JJ cord-301276-eer1l8vg 29 29 consequences consequence NNS cord-301276-eer1l8vg 29 30 of of IN cord-301276-eer1l8vg 29 31 COVID-19 covid-19 JJ cord-301276-eer1l8vg 29 32 infection infection NN cord-301276-eer1l8vg 29 33 than than IN cord-301276-eer1l8vg 29 34 are be VBP cord-301276-eer1l8vg 29 35 others other NNS cord-301276-eer1l8vg 29 36 ? ? . cord-301276-eer1l8vg 30 1 We -PRON- PRP cord-301276-eer1l8vg 30 2 suspect suspect VBP cord-301276-eer1l8vg 30 3 that that IN cord-301276-eer1l8vg 30 4 the the DT cord-301276-eer1l8vg 30 5 hygiene hygiene NN cord-301276-eer1l8vg 30 6 hypothesis hypothesis NN cord-301276-eer1l8vg 30 7 is be VBZ cord-301276-eer1l8vg 30 8 a a DT cord-301276-eer1l8vg 30 9 viable viable JJ cord-301276-eer1l8vg 30 10 concept concept NN cord-301276-eer1l8vg 30 11 that that WDT cord-301276-eer1l8vg 30 12 applies apply VBZ cord-301276-eer1l8vg 30 13 to to IN cord-301276-eer1l8vg 30 14 COVID-19 covid-19 VB cord-301276-eer1l8vg 30 15 susceptibility susceptibility NN cord-301276-eer1l8vg 30 16 , , , cord-301276-eer1l8vg 30 17 but but CC cord-301276-eer1l8vg 30 18 it -PRON- PRP cord-301276-eer1l8vg 30 19 could could MD cord-301276-eer1l8vg 30 20 be be VB cord-301276-eer1l8vg 30 21 a a DT cord-301276-eer1l8vg 30 22 long long JJ cord-301276-eer1l8vg 30 23 time time NN cord-301276-eer1l8vg 30 24 , , , cord-301276-eer1l8vg 30 25 even even RB cord-301276-eer1l8vg 30 26 in in IN cord-301276-eer1l8vg 30 27 this this DT cord-301276-eer1l8vg 30 28 era era NN cord-301276-eer1l8vg 30 29 of of IN cord-301276-eer1l8vg 30 30 accelerated accelerated JJ cord-301276-eer1l8vg 30 31 information information NN cord-301276-eer1l8vg 30 32 gathering gathering NN cord-301276-eer1l8vg 30 33 before before IN cord-301276-eer1l8vg 30 34 epidemiologists epidemiologist NNS cord-301276-eer1l8vg 30 35 could could MD cord-301276-eer1l8vg 30 36 assemble assemble VB cord-301276-eer1l8vg 30 37 evidence evidence NN cord-301276-eer1l8vg 30 38 that that IN cord-301276-eer1l8vg 30 39 early early JJ cord-301276-eer1l8vg 30 40 lifestyle lifestyle NN cord-301276-eer1l8vg 30 41 can can MD cord-301276-eer1l8vg 30 42 be be VB cord-301276-eer1l8vg 30 43 related relate VBN cord-301276-eer1l8vg 30 44 to to IN cord-301276-eer1l8vg 30 45 later later RB cord-301276-eer1l8vg 30 46 COVID-19 covid-19 VB cord-301276-eer1l8vg 30 47 susceptibility susceptibility NN cord-301276-eer1l8vg 30 48 . . . cord-301276-eer1l8vg 31 1 However however RB cord-301276-eer1l8vg 31 2 , , , cord-301276-eer1l8vg 31 3 it -PRON- PRP cord-301276-eer1l8vg 31 4 does do VBZ cord-301276-eer1l8vg 31 5 seem seem VB cord-301276-eer1l8vg 31 6 likely likely JJ cord-301276-eer1l8vg 31 7 that that IN cord-301276-eer1l8vg 31 8 extensive extensive JJ cord-301276-eer1l8vg 31 9 exposure exposure NN cord-301276-eer1l8vg 31 10 to to IN cord-301276-eer1l8vg 31 11 multiple multiple JJ cord-301276-eer1l8vg 31 12 microbes microbe NNS cord-301276-eer1l8vg 31 13 in in IN cord-301276-eer1l8vg 31 14 the the DT cord-301276-eer1l8vg 31 15 environment environment NN cord-301276-eer1l8vg 31 16 , , , cord-301276-eer1l8vg 31 17 food food NN cord-301276-eer1l8vg 31 18 and and CC cord-301276-eer1l8vg 31 19 water water NN cord-301276-eer1l8vg 31 20 , , , cord-301276-eer1l8vg 31 21 as as IN cord-301276-eer1l8vg 31 22 commonly commonly RB cord-301276-eer1l8vg 31 23 occurs occur VBZ cord-301276-eer1l8vg 31 24 among among IN cord-301276-eer1l8vg 31 25 those those DT cord-301276-eer1l8vg 31 26 that that WDT cord-301276-eer1l8vg 31 27 reside reside VBP cord-301276-eer1l8vg 31 28 in in IN cord-301276-eer1l8vg 31 29 depressed depressed JJ cord-301276-eer1l8vg 31 30 socioeconomic socioeconomic JJ cord-301276-eer1l8vg 31 31 circumstances circumstance NNS cord-301276-eer1l8vg 31 32 , , , cord-301276-eer1l8vg 31 33 may may MD cord-301276-eer1l8vg 31 34 render render VB cord-301276-eer1l8vg 31 35 them -PRON- PRP cord-301276-eer1l8vg 31 36 resistant resistant JJ cord-301276-eer1l8vg 31 37 to to IN cord-301276-eer1l8vg 31 38 the the DT cord-301276-eer1l8vg 31 39 more more RBR cord-301276-eer1l8vg 31 40 severe severe JJ cord-301276-eer1l8vg 31 41 consequences consequence NNS cord-301276-eer1l8vg 31 42 of of IN cord-301276-eer1l8vg 31 43 COVID-19 covid-19 JJ cord-301276-eer1l8vg 31 44 infection infection NN cord-301276-eer1l8vg 31 45 . . . cord-301276-eer1l8vg 32 1 Similarly similarly RB cord-301276-eer1l8vg 32 2 , , , cord-301276-eer1l8vg 32 3 the the DT cord-301276-eer1l8vg 32 4 numbers number NNS cord-301276-eer1l8vg 32 5 of of IN cord-301276-eer1l8vg 32 6 recorded record VBN cord-301276-eer1l8vg 32 7 cases case NNS cord-301276-eer1l8vg 32 8 and and CC cord-301276-eer1l8vg 32 9 deaths death NNS cord-301276-eer1l8vg 32 10 in in IN cord-301276-eer1l8vg 32 11 other other JJ cord-301276-eer1l8vg 32 12 societies society NNS cord-301276-eer1l8vg 32 13 with with IN cord-301276-eer1l8vg 32 14 low low JJ cord-301276-eer1l8vg 32 15 socioeconomic socioeconomic JJ cord-301276-eer1l8vg 32 16 status status NN cord-301276-eer1l8vg 32 17 have have VBP cord-301276-eer1l8vg 32 18 experienced experience VBN cord-301276-eer1l8vg 32 19 far far RB cord-301276-eer1l8vg 32 20 fewer few JJR cord-301276-eer1l8vg 32 21 cases case NNS cord-301276-eer1l8vg 32 22 than than IN cord-301276-eer1l8vg 32 23 many many JJ cord-301276-eer1l8vg 32 24 developed develop VBN cord-301276-eer1l8vg 32 25 countries country NNS cord-301276-eer1l8vg 32 26 ( ( -LRB- cord-301276-eer1l8vg 32 27 11 11 CD cord-301276-eer1l8vg 32 28 ) ) -RRB- cord-301276-eer1l8vg 32 29 . . . cord-301276-eer1l8vg 33 1 Although although IN cord-301276-eer1l8vg 33 2 the the DT cord-301276-eer1l8vg 33 3 efficiency efficiency NN cord-301276-eer1l8vg 33 4 of of IN cord-301276-eer1l8vg 33 5 recording record VBG cord-301276-eer1l8vg 33 6 all all DT cord-301276-eer1l8vg 33 7 cases case NNS cord-301276-eer1l8vg 33 8 of of IN cord-301276-eer1l8vg 33 9 COVID-19 covid-19 JJ cord-301276-eer1l8vg 33 10 infection infection NN cord-301276-eer1l8vg 33 11 and and CC cord-301276-eer1l8vg 33 12 its -PRON- PRP$ cord-301276-eer1l8vg 33 13 consequence consequence NN cord-301276-eer1l8vg 33 14 varies vary VBZ cord-301276-eer1l8vg 33 15 markedly markedly RB cord-301276-eer1l8vg 33 16 between between IN cord-301276-eer1l8vg 33 17 different different JJ cord-301276-eer1l8vg 33 18 countries country NNS cord-301276-eer1l8vg 33 19 , , , cord-301276-eer1l8vg 33 20 gathering gather VBG cord-301276-eer1l8vg 33 21 evidence evidence NN cord-301276-eer1l8vg 33 22 supports support VBZ cord-301276-eer1l8vg 33 23 the the DT cord-301276-eer1l8vg 33 24 idea idea NN cord-301276-eer1l8vg 33 25 that that IN cord-301276-eer1l8vg 33 26 the the DT cord-301276-eer1l8vg 33 27 outcome outcome NN cord-301276-eer1l8vg 33 28 of of IN cord-301276-eer1l8vg 33 29 infection infection NN cord-301276-eer1l8vg 33 30 is be VBZ cord-301276-eer1l8vg 33 31 more more RBR cord-301276-eer1l8vg 33 32 likely likely JJ cord-301276-eer1l8vg 33 33 to to TO cord-301276-eer1l8vg 33 34 be be VB cord-301276-eer1l8vg 33 35 asymptomatic asymptomatic JJ cord-301276-eer1l8vg 33 36 or or CC cord-301276-eer1l8vg 33 37 mild mild JJ cord-301276-eer1l8vg 33 38 in in IN cord-301276-eer1l8vg 33 39 developing develop VBG cord-301276-eer1l8vg 33 40 countries country NNS cord-301276-eer1l8vg 33 41 and and CC cord-301276-eer1l8vg 33 42 rarely rarely RB cord-301276-eer1l8vg 33 43 has have VBZ cord-301276-eer1l8vg 33 44 lethal lethal JJ cord-301276-eer1l8vg 33 45 consequences consequence NNS cord-301276-eer1l8vg 33 46 . . . cord-301276-eer1l8vg 34 1 Thus thus RB cord-301276-eer1l8vg 34 2 , , , cord-301276-eer1l8vg 34 3 the the DT cord-301276-eer1l8vg 34 4 WHO WHO NNP cord-301276-eer1l8vg 34 5 statistics statistic NNS cord-301276-eer1l8vg 34 6 show show VBP cord-301276-eer1l8vg 34 7 lethality lethality NN cord-301276-eer1l8vg 34 8 rates rate NNS cord-301276-eer1l8vg 34 9 that that WDT cord-301276-eer1l8vg 34 10 vary vary VBP cord-301276-eer1l8vg 34 11 from from IN cord-301276-eer1l8vg 34 12 0.3 0.3 CD cord-301276-eer1l8vg 34 13 % % NN cord-301276-eer1l8vg 34 14 to to TO cord-301276-eer1l8vg 34 15 10 10 CD cord-301276-eer1l8vg 34 16 % % NN cord-301276-eer1l8vg 34 17 with with IN cord-301276-eer1l8vg 34 18 the the DT cord-301276-eer1l8vg 34 19 latter latter JJ cord-301276-eer1l8vg 34 20 occurring occur VBG cord-301276-eer1l8vg 34 21 in in IN cord-301276-eer1l8vg 34 22 some some DT cord-301276-eer1l8vg 34 23 developed develop VBN cord-301276-eer1l8vg 34 24 countries country NNS cord-301276-eer1l8vg 34 25 ( ( -LRB- cord-301276-eer1l8vg 34 26 2,11 2,11 CD cord-301276-eer1l8vg 34 27 ) ) -RRB- cord-301276-eer1l8vg 34 28 . . . cord-301276-eer1l8vg 35 1 Severe severe JJ cord-301276-eer1l8vg 35 2 disease disease NN cord-301276-eer1l8vg 35 3 necessitating necessitate VBG cord-301276-eer1l8vg 35 4 hospitalization hospitalization NN cord-301276-eer1l8vg 35 5 and and CC cord-301276-eer1l8vg 35 6 oxygen oxygen NN cord-301276-eer1l8vg 35 7 supplementation supplementation NN cord-301276-eer1l8vg 35 8 is be VBZ cord-301276-eer1l8vg 35 9 also also RB cord-301276-eer1l8vg 35 10 more more RBR cord-301276-eer1l8vg 35 11 common common JJ cord-301276-eer1l8vg 35 12 in in IN cord-301276-eer1l8vg 35 13 developed develop VBN cord-301276-eer1l8vg 35 14 as as IN cord-301276-eer1l8vg 35 15 compared compare VBN cord-301276-eer1l8vg 35 16 to to IN cord-301276-eer1l8vg 35 17 most most JJS cord-301276-eer1l8vg 35 18 developing develop VBG cord-301276-eer1l8vg 35 19 countries country NNS cord-301276-eer1l8vg 35 20 . . . cord-301276-eer1l8vg 36 1 If if IN cord-301276-eer1l8vg 36 2 as as IN cord-301276-eer1l8vg 36 3 increasing increase VBG cord-301276-eer1l8vg 36 4 evidence evidence NN cord-301276-eer1l8vg 36 5 is be VBZ cord-301276-eer1l8vg 36 6 showing show VBG cord-301276-eer1l8vg 36 7 COVID-19 COVID-19 JJR cord-301276-eer1l8vg 36 8 infection infection NN cord-301276-eer1l8vg 36 9 is be VBZ cord-301276-eer1l8vg 36 10 of of IN cord-301276-eer1l8vg 36 11 less less JJR cord-301276-eer1l8vg 36 12 severity severity NN cord-301276-eer1l8vg 36 13 in in IN cord-301276-eer1l8vg 36 14 developing develop VBG cord-301276-eer1l8vg 36 15 countries country NNS cord-301276-eer1l8vg 36 16 , , , cord-301276-eer1l8vg 36 17 how how WRB cord-301276-eer1l8vg 36 18 can can MD cord-301276-eer1l8vg 36 19 this this DT cord-301276-eer1l8vg 36 20 be be VB cord-301276-eer1l8vg 36 21 explained explain VBN cord-301276-eer1l8vg 36 22 ? ? . cord-301276-eer1l8vg 37 1 Even even RB cord-301276-eer1l8vg 37 2 more more RBR cord-301276-eer1l8vg 37 3 important important JJ cord-301276-eer1l8vg 37 4 , , , cord-301276-eer1l8vg 37 5 can can MD cord-301276-eer1l8vg 37 6 the the DT cord-301276-eer1l8vg 37 7 information information NN cord-301276-eer1l8vg 37 8 be be VB cord-301276-eer1l8vg 37 9 applied apply VBN cord-301276-eer1l8vg 37 10 to to TO cord-301276-eer1l8vg 37 11 reduce reduce VB cord-301276-eer1l8vg 37 12 the the DT cord-301276-eer1l8vg 37 13 consequences consequence NNS cord-301276-eer1l8vg 37 14 of of IN cord-301276-eer1l8vg 37 15 infection infection NN cord-301276-eer1l8vg 37 16 in in IN cord-301276-eer1l8vg 37 17 the the DT cord-301276-eer1l8vg 37 18 developed develop VBN cord-301276-eer1l8vg 37 19 world world NN cord-301276-eer1l8vg 37 20 ? ? . cord-301276-eer1l8vg 38 1 The the DT cord-301276-eer1l8vg 38 2 most most RBS cord-301276-eer1l8vg 38 3 likely likely JJ cord-301276-eer1l8vg 38 4 explanation explanation NN cord-301276-eer1l8vg 38 5 for for IN cord-301276-eer1l8vg 38 6 the the DT cord-301276-eer1l8vg 38 7 different different JJ cord-301276-eer1l8vg 38 8 manifestations manifestation NNS cord-301276-eer1l8vg 38 9 is be VBZ cord-301276-eer1l8vg 38 10 that that IN cord-301276-eer1l8vg 38 11 repeated repeat VBN cord-301276-eer1l8vg 38 12 exposure exposure NN cord-301276-eer1l8vg 38 13 to to IN cord-301276-eer1l8vg 38 14 unhygienic unhygienic JJ cord-301276-eer1l8vg 38 15 conditions condition NNS cord-301276-eer1l8vg 38 16 exposes expose VBZ cord-301276-eer1l8vg 38 17 persons person NNS cord-301276-eer1l8vg 38 18 to to IN cord-301276-eer1l8vg 38 19 microbes microbe NNS cord-301276-eer1l8vg 38 20 that that WDT cord-301276-eer1l8vg 38 21 express express VBP cord-301276-eer1l8vg 38 22 multiple multiple JJ cord-301276-eer1l8vg 38 23 so so RB cord-301276-eer1l8vg 38 24 - - HYPH cord-301276-eer1l8vg 38 25 called call VBN cord-301276-eer1l8vg 38 26 pathogen pathogen NN cord-301276-eer1l8vg 38 27 associated associate VBD cord-301276-eer1l8vg 38 28 molecular molecular JJ cord-301276-eer1l8vg 38 29 patterns pattern NNS cord-301276-eer1l8vg 38 30 that that WDT cord-301276-eer1l8vg 38 31 activate activate VBP cord-301276-eer1l8vg 38 32 one one CD cord-301276-eer1l8vg 38 33 or or CC cord-301276-eer1l8vg 38 34 more more JJR cord-301276-eer1l8vg 38 35 aspects aspect NNS cord-301276-eer1l8vg 38 36 of of IN cord-301276-eer1l8vg 38 37 innate innate JJ cord-301276-eer1l8vg 38 38 immunity immunity NN cord-301276-eer1l8vg 38 39 . . . cord-301276-eer1l8vg 39 1 This this DT cord-301276-eer1l8vg 39 2 changed change VBN cord-301276-eer1l8vg 39 3 activation activation NN cord-301276-eer1l8vg 39 4 state state NN cord-301276-eer1l8vg 39 5 , , , cord-301276-eer1l8vg 39 6 which which WDT cord-301276-eer1l8vg 39 7 may may MD cord-301276-eer1l8vg 39 8 persist persist VB cord-301276-eer1l8vg 39 9 for for IN cord-301276-eer1l8vg 39 10 months month NNS cord-301276-eer1l8vg 39 11 but but CC cord-301276-eer1l8vg 39 12 will will MD cord-301276-eer1l8vg 39 13 not not RB cord-301276-eer1l8vg 39 14 remain remain VB cord-301276-eer1l8vg 39 15 indefinitely indefinitely RB cord-301276-eer1l8vg 39 16 ( ( -LRB- cord-301276-eer1l8vg 39 17 12 12 CD cord-301276-eer1l8vg 39 18 ) ) -RRB- cord-301276-eer1l8vg 39 19 , , , cord-301276-eer1l8vg 39 20 is be VBZ cord-301276-eer1l8vg 39 21 often often RB cord-301276-eer1l8vg 39 22 referred refer VBN cord-301276-eer1l8vg 39 23 to to IN cord-301276-eer1l8vg 39 24 as as IN cord-301276-eer1l8vg 39 25 trained train VBN cord-301276-eer1l8vg 39 26 immunity immunity NN cord-301276-eer1l8vg 39 27 and and CC cord-301276-eer1l8vg 39 28 unlike unlike IN cord-301276-eer1l8vg 39 29 adaptive adaptive JJ cord-301276-eer1l8vg 39 30 immunity immunity NN cord-301276-eer1l8vg 39 31 is be VBZ cord-301276-eer1l8vg 39 32 not not RB cord-301276-eer1l8vg 39 33 highly highly RB cord-301276-eer1l8vg 39 34 antigen antigen NN cord-301276-eer1l8vg 39 35 - - HYPH cord-301276-eer1l8vg 39 36 specific specific JJ cord-301276-eer1l8vg 39 37 , , , cord-301276-eer1l8vg 39 38 is be VBZ cord-301276-eer1l8vg 39 39 less less RBR cord-301276-eer1l8vg 39 40 robust robust JJ cord-301276-eer1l8vg 39 41 and and CC cord-301276-eer1l8vg 39 42 has have VBZ cord-301276-eer1l8vg 39 43 minimal minimal JJ cord-301276-eer1l8vg 39 44 or or CC cord-301276-eer1l8vg 39 45 no no DT cord-301276-eer1l8vg 39 46 long long JJ cord-301276-eer1l8vg 39 47 - - HYPH cord-301276-eer1l8vg 39 48 term term NN cord-301276-eer1l8vg 39 49 memory memory NN cord-301276-eer1l8vg 39 50 ( ( -LRB- cord-301276-eer1l8vg 39 51 12 12 CD cord-301276-eer1l8vg 39 52 , , , cord-301276-eer1l8vg 39 53 13 13 CD cord-301276-eer1l8vg 39 54 ) ) -RRB- cord-301276-eer1l8vg 39 55 . . . cord-301276-eer1l8vg 40 1 However however RB cord-301276-eer1l8vg 40 2 , , , cord-301276-eer1l8vg 40 3 trained train VBN cord-301276-eer1l8vg 40 4 immunity immunity NN cord-301276-eer1l8vg 40 5 's 's POS cord-301276-eer1l8vg 40 6 advantage advantage NN cord-301276-eer1l8vg 40 7 is be VBZ cord-301276-eer1l8vg 40 8 that that IN cord-301276-eer1l8vg 40 9 the the DT cord-301276-eer1l8vg 40 10 response response NN cord-301276-eer1l8vg 40 11 generated generate VBD cord-301276-eer1l8vg 40 12 against against IN cord-301276-eer1l8vg 40 13 one one CD cord-301276-eer1l8vg 40 14 set set NN cord-301276-eer1l8vg 40 15 of of IN cord-301276-eer1l8vg 40 16 microbes microbe NNS cord-301276-eer1l8vg 40 17 can can MD cord-301276-eer1l8vg 40 18 have have VB cord-301276-eer1l8vg 40 19 bystander bystander NN cord-301276-eer1l8vg 40 20 immune immune JJ cord-301276-eer1l8vg 40 21 protection protection NN cord-301276-eer1l8vg 40 22 against against IN cord-301276-eer1l8vg 40 23 other other JJ cord-301276-eer1l8vg 40 24 infections infection NNS cord-301276-eer1l8vg 40 25 . . . cord-301276-eer1l8vg 41 1 This this DT cord-301276-eer1l8vg 41 2 phenomenon phenomenon NN cord-301276-eer1l8vg 41 3 was be VBD cord-301276-eer1l8vg 41 4 fist fist NN cord-301276-eer1l8vg 41 5 advocated advocate VBN cord-301276-eer1l8vg 41 6 by by IN cord-301276-eer1l8vg 41 7 the the DT cord-301276-eer1l8vg 41 8 MacKaness MacKaness NNP cord-301276-eer1l8vg 41 9 and and CC cord-301276-eer1l8vg 41 10 Nathan Nathan NNP cord-301276-eer1l8vg 41 11 groups group NNS cord-301276-eer1l8vg 41 12 in in IN cord-301276-eer1l8vg 41 13 the the DT cord-301276-eer1l8vg 41 14 early early JJ cord-301276-eer1l8vg 41 15 60s 60 NNS cord-301276-eer1l8vg 41 16 with with IN cord-301276-eer1l8vg 41 17 the the DT cord-301276-eer1l8vg 41 18 bystander bystander NN cord-301276-eer1l8vg 41 19 immune immune JJ cord-301276-eer1l8vg 41 20 effect effect NN cord-301276-eer1l8vg 41 21 being be VBG cord-301276-eer1l8vg 41 22 attributed attribute VBN cord-301276-eer1l8vg 41 23 to to IN cord-301276-eer1l8vg 41 24 so so RB cord-301276-eer1l8vg 41 25 - - HYPH cord-301276-eer1l8vg 41 26 called call VBN cord-301276-eer1l8vg 41 27 activated activate VBN cord-301276-eer1l8vg 41 28 or or CC cord-301276-eer1l8vg 41 29 angry angry JJ cord-301276-eer1l8vg 41 30 macrophages macrophage NNS cord-301276-eer1l8vg 41 31 , , , cord-301276-eer1l8vg 41 32 terms term NNS cord-301276-eer1l8vg 41 33 seldom seldom RB cord-301276-eer1l8vg 41 34 used use VBD cord-301276-eer1l8vg 41 35 these these DT cord-301276-eer1l8vg 41 36 days day NNS cord-301276-eer1l8vg 41 37 ( ( -LRB- cord-301276-eer1l8vg 41 38 14 14 CD cord-301276-eer1l8vg 41 39 , , , cord-301276-eer1l8vg 41 40 15 15 CD cord-301276-eer1l8vg 41 41 ) ) -RRB- cord-301276-eer1l8vg 41 42 . . . cord-301276-eer1l8vg 42 1 We -PRON- PRP cord-301276-eer1l8vg 42 2 now now RB cord-301276-eer1l8vg 42 3 realize realize VBP cord-301276-eer1l8vg 42 4 that that IN cord-301276-eer1l8vg 42 5 bystander bystander NN cord-301276-eer1l8vg 42 6 immunity immunity NN cord-301276-eer1l8vg 42 7 can can MD cord-301276-eer1l8vg 42 8 be be VB cord-301276-eer1l8vg 42 9 attributed attribute VBN cord-301276-eer1l8vg 42 10 to to IN cord-301276-eer1l8vg 42 11 many many JJ cord-301276-eer1l8vg 42 12 cell cell NN cord-301276-eer1l8vg 42 13 types type NNS cord-301276-eer1l8vg 42 14 such such JJ cord-301276-eer1l8vg 42 15 as as IN cord-301276-eer1l8vg 42 16 natural natural JJ cord-301276-eer1l8vg 42 17 killer killer NN cord-301276-eer1l8vg 42 18 cells cell NNS cord-301276-eer1l8vg 42 19 , , , cord-301276-eer1l8vg 42 20 dendritic dendritic JJ cord-301276-eer1l8vg 42 21 cells cell NNS cord-301276-eer1l8vg 42 22 , , , cord-301276-eer1l8vg 42 23 innate innate JJ cord-301276-eer1l8vg 42 24 lymphocytes lymphocyte NNS cord-301276-eer1l8vg 42 25 , , , cord-301276-eer1l8vg 42 26 gamma gamma NN cord-301276-eer1l8vg 42 27 delta delta NN cord-301276-eer1l8vg 42 28 T T NNP cord-301276-eer1l8vg 42 29 cells cell NNS cord-301276-eer1l8vg 42 30 in in IN cord-301276-eer1l8vg 42 31 addition addition NN cord-301276-eer1l8vg 42 32 to to IN cord-301276-eer1l8vg 42 33 macrophages macrophage NNS cord-301276-eer1l8vg 42 34 ( ( -LRB- cord-301276-eer1l8vg 42 35 12 12 CD cord-301276-eer1l8vg 42 36 ) ) -RRB- cord-301276-eer1l8vg 42 37 . . . cord-301276-eer1l8vg 43 1 The the DT cord-301276-eer1l8vg 43 2 fact fact NN cord-301276-eer1l8vg 43 3 that that IN cord-301276-eer1l8vg 43 4 trained train VBN cord-301276-eer1l8vg 43 5 immunity immunity NN cord-301276-eer1l8vg 43 6 can can MD cord-301276-eer1l8vg 43 7 be be VB cord-301276-eer1l8vg 43 8 induced induce VBN cord-301276-eer1l8vg 43 9 raises raise VBZ cord-301276-eer1l8vg 43 10 the the DT cord-301276-eer1l8vg 43 11 prospect prospect NN cord-301276-eer1l8vg 43 12 of of IN cord-301276-eer1l8vg 43 13 its -PRON- PRP$ cord-301276-eer1l8vg 43 14 exploitation exploitation NN cord-301276-eer1l8vg 43 15 to to TO cord-301276-eer1l8vg 43 16 raise raise VB cord-301276-eer1l8vg 43 17 the the DT cord-301276-eer1l8vg 43 18 threshold threshold NN cord-301276-eer1l8vg 43 19 of of IN cord-301276-eer1l8vg 43 20 resistance resistance NN cord-301276-eer1l8vg 43 21 to to IN cord-301276-eer1l8vg 43 22 COVID-19 covid-19 JJ cord-301276-eer1l8vg 43 23 infection infection NN cord-301276-eer1l8vg 43 24 , , , cord-301276-eer1l8vg 43 25 a a DT cord-301276-eer1l8vg 43 26 valuable valuable JJ cord-301276-eer1l8vg 43 27 maneuver maneuver NN cord-301276-eer1l8vg 43 28 during during IN cord-301276-eer1l8vg 43 29 the the DT cord-301276-eer1l8vg 43 30 time time NN cord-301276-eer1l8vg 43 31 when when WRB cord-301276-eer1l8vg 43 32 we -PRON- PRP cord-301276-eer1l8vg 43 33 have have VBP cord-301276-eer1l8vg 43 34 yet yet RB cord-301276-eer1l8vg 43 35 to to TO cord-301276-eer1l8vg 43 36 develop develop VB cord-301276-eer1l8vg 43 37 effective effective JJ cord-301276-eer1l8vg 43 38 treatments treatment NNS cord-301276-eer1l8vg 43 39 or or CC cord-301276-eer1l8vg 43 40 vaccines vaccine NNS cord-301276-eer1l8vg 43 41 . . . cord-301276-eer1l8vg 44 1 The the DT cord-301276-eer1l8vg 44 2 questions question NNS cord-301276-eer1l8vg 44 3 will will MD cord-301276-eer1l8vg 44 4 include include VB cord-301276-eer1l8vg 44 5 what what WP cord-301276-eer1l8vg 44 6 approaches approach NNS cord-301276-eer1l8vg 44 7 could could MD cord-301276-eer1l8vg 44 8 be be VB cord-301276-eer1l8vg 44 9 used use VBN cord-301276-eer1l8vg 44 10 to to TO cord-301276-eer1l8vg 44 11 achieve achieve VB cord-301276-eer1l8vg 44 12 trained train VBN cord-301276-eer1l8vg 44 13 immunity immunity NN cord-301276-eer1l8vg 44 14 and and CC cord-301276-eer1l8vg 44 15 how how WRB cord-301276-eer1l8vg 44 16 long long RB cord-301276-eer1l8vg 44 17 they -PRON- PRP cord-301276-eer1l8vg 44 18 will will MD cord-301276-eer1l8vg 44 19 be be VB cord-301276-eer1l8vg 44 20 useful useful JJ cord-301276-eer1l8vg 44 21 . . . cord-301276-eer1l8vg 45 1 Some some DT cord-301276-eer1l8vg 45 2 studies study NNS cord-301276-eer1l8vg 45 3 have have VBP cord-301276-eer1l8vg 45 4 already already RB cord-301276-eer1l8vg 45 5 shown show VBN cord-301276-eer1l8vg 45 6 that that IN cord-301276-eer1l8vg 45 7 communities community NNS cord-301276-eer1l8vg 45 8 that that WDT cord-301276-eer1l8vg 45 9 still still RB cord-301276-eer1l8vg 45 10 use use VBP cord-301276-eer1l8vg 45 11 Bacillus Bacillus NNP cord-301276-eer1l8vg 45 12 Calmette Calmette NNP cord-301276-eer1l8vg 45 13 - - HYPH cord-301276-eer1l8vg 45 14 Guérin Guérin NNP cord-301276-eer1l8vg 45 15 ( ( -LRB- cord-301276-eer1l8vg 45 16 BCG BCG NNP cord-301276-eer1l8vg 45 17 ) ) -RRB- cord-301276-eer1l8vg 45 18 as as IN cord-301276-eer1l8vg 45 19 a a DT cord-301276-eer1l8vg 45 20 vaccine vaccine NN cord-301276-eer1l8vg 45 21 against against IN cord-301276-eer1l8vg 45 22 tuberculosis tuberculosis NN cord-301276-eer1l8vg 45 23 may may MD cord-301276-eer1l8vg 45 24 have have VB cord-301276-eer1l8vg 45 25 lesser less JJR cord-301276-eer1l8vg 45 26 instances instance NNS cord-301276-eer1l8vg 45 27 of of IN cord-301276-eer1l8vg 45 28 severe severe JJ cord-301276-eer1l8vg 45 29 COVID-19 covid-19 JJ cord-301276-eer1l8vg 45 30 infection infection NN cord-301276-eer1l8vg 45 31 than than IN cord-301276-eer1l8vg 45 32 those those DT cord-301276-eer1l8vg 45 33 countries country NNS cord-301276-eer1l8vg 45 34 that that WDT cord-301276-eer1l8vg 45 35 do do VBP cord-301276-eer1l8vg 45 36 not not RB cord-301276-eer1l8vg 45 37 use use VB cord-301276-eer1l8vg 45 38 BCG BCG NNP cord-301276-eer1l8vg 45 39 ( ( -LRB- cord-301276-eer1l8vg 45 40 16 16 CD cord-301276-eer1l8vg 45 41 ) ) -RRB- cord-301276-eer1l8vg 45 42 . . . cord-301276-eer1l8vg 46 1 This this DT cord-301276-eer1l8vg 46 2 notion notion NN cord-301276-eer1l8vg 46 3 has have VBZ cord-301276-eer1l8vg 46 4 been be VBN cord-301276-eer1l8vg 46 5 complemented complement VBN cord-301276-eer1l8vg 46 6 by by IN cord-301276-eer1l8vg 46 7 advocating advocate VBG cord-301276-eer1l8vg 46 8 the the DT cord-301276-eer1l8vg 46 9 use use NN cord-301276-eer1l8vg 46 10 of of IN cord-301276-eer1l8vg 46 11 BCG BCG NNP cord-301276-eer1l8vg 46 12 to to TO cord-301276-eer1l8vg 46 13 vaccinate vaccinate VB cord-301276-eer1l8vg 46 14 persons person NNS cord-301276-eer1l8vg 46 15 in in IN cord-301276-eer1l8vg 46 16 an an DT cord-301276-eer1l8vg 46 17 attempt attempt NN cord-301276-eer1l8vg 46 18 to to TO cord-301276-eer1l8vg 46 19 protect protect VB cord-301276-eer1l8vg 46 20 them -PRON- PRP cord-301276-eer1l8vg 46 21 against against IN cord-301276-eer1l8vg 46 22 . . . cord-301276-eer1l8vg 47 1 A a DT cord-301276-eer1l8vg 47 2 recent recent JJ cord-301276-eer1l8vg 47 3 letter letter NN cord-301276-eer1l8vg 47 4 by by IN cord-301276-eer1l8vg 47 5 HIV HIV NNP cord-301276-eer1l8vg 47 6 pioneer pioneer NN cord-301276-eer1l8vg 47 7 Bob Bob NNP cord-301276-eer1l8vg 47 8 Gallo Gallo NNP cord-301276-eer1l8vg 47 9 advocated advocate VBD cord-301276-eer1l8vg 47 10 using use VBG cord-301276-eer1l8vg 47 11 oral oral JJ cord-301276-eer1l8vg 47 12 polio polio NN cord-301276-eer1l8vg 47 13 vaccine vaccine NN cord-301276-eer1l8vg 47 14 for for IN cord-301276-eer1l8vg 47 15 a a DT cord-301276-eer1l8vg 47 16 similar similar JJ cord-301276-eer1l8vg 47 17 effect effect NN cord-301276-eer1l8vg 47 18 ( ( -LRB- cord-301276-eer1l8vg 47 19 17 17 CD cord-301276-eer1l8vg 47 20 ) ) -RRB- cord-301276-eer1l8vg 47 21 . . . cord-301276-eer1l8vg 48 1 We -PRON- PRP cord-301276-eer1l8vg 48 2 consider consider VBP cord-301276-eer1l8vg 48 3 that that DT cord-301276-eer1l8vg 48 4 administration administration NN cord-301276-eer1l8vg 48 5 of of IN cord-301276-eer1l8vg 48 6 galectin galectin NNP cord-301276-eer1l8vg 48 7 molecules molecule NNS cord-301276-eer1l8vg 48 8 , , , cord-301276-eer1l8vg 48 9 some some DT cord-301276-eer1l8vg 48 10 of of IN cord-301276-eer1l8vg 48 11 which which WDT cord-301276-eer1l8vg 48 12 can can MD cord-301276-eer1l8vg 48 13 activate activate VB cord-301276-eer1l8vg 48 14 the the DT cord-301276-eer1l8vg 48 15 innate innate JJ cord-301276-eer1l8vg 48 16 immune immune JJ cord-301276-eer1l8vg 48 17 system system NN cord-301276-eer1l8vg 48 18 might may MD cord-301276-eer1l8vg 48 19 also also RB cord-301276-eer1l8vg 48 20 represent represent VB cord-301276-eer1l8vg 48 21 an an DT cord-301276-eer1l8vg 48 22 approach approach NN cord-301276-eer1l8vg 48 23 to to TO cord-301276-eer1l8vg 48 24 reduce reduce VB cord-301276-eer1l8vg 48 25 the the DT cord-301276-eer1l8vg 48 26 consequences consequence NNS cord-301276-eer1l8vg 48 27 of of IN cord-301276-eer1l8vg 48 28 COVID-19 covid-19 JJ cord-301276-eer1l8vg 48 29 infection infection NN cord-301276-eer1l8vg 48 30 ( ( -LRB- cord-301276-eer1l8vg 48 31 18 18 CD cord-301276-eer1l8vg 48 32 ) ) -RRB- cord-301276-eer1l8vg 48 33 . . . cord-301276-eer1l8vg 49 1 It -PRON- PRP cord-301276-eer1l8vg 49 2 is be VBZ cord-301276-eer1l8vg 49 3 also also RB cord-301276-eer1l8vg 49 4 worth worth JJ cord-301276-eer1l8vg 49 5 noting note VBG cord-301276-eer1l8vg 49 6 that that IN cord-301276-eer1l8vg 49 7 galectin galectin NNP cord-301276-eer1l8vg 49 8 therapy therapy NN cord-301276-eer1l8vg 49 9 also also RB cord-301276-eer1l8vg 49 10 has have VBZ cord-301276-eer1l8vg 49 11 the the DT cord-301276-eer1l8vg 49 12 potential potential NN cord-301276-eer1l8vg 49 13 to to TO cord-301276-eer1l8vg 49 14 reduce reduce VB cord-301276-eer1l8vg 49 15 the the DT cord-301276-eer1l8vg 49 16 severity severity NN cord-301276-eer1l8vg 49 17 of of IN cord-301276-eer1l8vg 49 18 COVID-19 COVID-19 NNP cord-301276-eer1l8vg 49 19 once once RB cord-301276-eer1l8vg 49 20 infected infect VBN cord-301276-eer1l8vg 49 21 . . . cord-301276-eer1l8vg 50 1 Thus thus RB cord-301276-eer1l8vg 50 2 , , , cord-301276-eer1l8vg 50 3 galectins galectin NNS cord-301276-eer1l8vg 50 4 such such JJ cord-301276-eer1l8vg 50 5 as as IN cord-301276-eer1l8vg 50 6 galectin-9 galectin-9 NNP cord-301276-eer1l8vg 50 7 can can MD cord-301276-eer1l8vg 50 8 reduce reduce VB cord-301276-eer1l8vg 50 9 inflammatory inflammatory JJ cord-301276-eer1l8vg 50 10 cytokine cytokine NN cord-301276-eer1l8vg 50 11 production production NN cord-301276-eer1l8vg 50 12 and and CC cord-301276-eer1l8vg 50 13 change change VB cord-301276-eer1l8vg 50 14 the the DT cord-301276-eer1l8vg 50 15 nature nature NN cord-301276-eer1l8vg 50 16 of of IN cord-301276-eer1l8vg 50 17 the the DT cord-301276-eer1l8vg 50 18 inflammatory inflammatory JJ cord-301276-eer1l8vg 50 19 response response NN cord-301276-eer1l8vg 50 20 caused cause VBN cord-301276-eer1l8vg 50 21 by by IN cord-301276-eer1l8vg 50 22 some some DT cord-301276-eer1l8vg 50 23 viral viral JJ cord-301276-eer1l8vg 50 24 lesions lesion NNS cord-301276-eer1l8vg 50 25 from from IN cord-301276-eer1l8vg 50 26 a a DT cord-301276-eer1l8vg 50 27 tissue tissue NN cord-301276-eer1l8vg 50 28 damaging damaging JJ cord-301276-eer1l8vg 50 29 reaction reaction NN cord-301276-eer1l8vg 50 30 dominated dominate VBN cord-301276-eer1l8vg 50 31 by by IN cord-301276-eer1l8vg 50 32 pro pro JJ cord-301276-eer1l8vg 50 33 - - JJ cord-301276-eer1l8vg 50 34 inflammatory inflammatory JJ cord-301276-eer1l8vg 50 35 T t NN cord-301276-eer1l8vg 50 36 cells cell NNS cord-301276-eer1l8vg 50 37 to to IN cord-301276-eer1l8vg 50 38 one one CD cord-301276-eer1l8vg 50 39 where where WRB cord-301276-eer1l8vg 50 40 counter counter JJ cord-301276-eer1l8vg 50 41 - - JJ cord-301276-eer1l8vg 50 42 inflammatory inflammatory JJ cord-301276-eer1l8vg 50 43 regulatory regulatory JJ cord-301276-eer1l8vg 50 44 T t NN cord-301276-eer1l8vg 50 45 cells cell NNS cord-301276-eer1l8vg 50 46 predominate predominate VBP cord-301276-eer1l8vg 50 47 ( ( -LRB- cord-301276-eer1l8vg 50 48 19 19 CD cord-301276-eer1l8vg 50 49 ) ) -RRB- cord-301276-eer1l8vg 50 50 . . . cord-301276-eer1l8vg 51 1 For for IN cord-301276-eer1l8vg 51 2 reasons reason NNS cord-301276-eer1l8vg 51 3 still still RB cord-301276-eer1l8vg 51 4 unknown unknown JJ cord-301276-eer1l8vg 51 5 , , , cord-301276-eer1l8vg 51 6 clinical clinical JJ cord-301276-eer1l8vg 51 7 disease disease NN cord-301276-eer1l8vg 51 8 following follow VBG cord-301276-eer1l8vg 51 9 COVID-19 covid-19 JJ cord-301276-eer1l8vg 51 10 infection infection NN cord-301276-eer1l8vg 51 11 in in IN cord-301276-eer1l8vg 51 12 children child NNS cord-301276-eer1l8vg 51 13 is be VBZ cord-301276-eer1l8vg 51 14 uncommon uncommon JJ cord-301276-eer1l8vg 51 15 in in IN cord-301276-eer1l8vg 51 16 all all DT cord-301276-eer1l8vg 51 17 communities community NNS cord-301276-eer1l8vg 51 18 . . . cord-301276-eer1l8vg 52 1 This this DT cord-301276-eer1l8vg 52 2 might may MD cord-301276-eer1l8vg 52 3 be be VB cord-301276-eer1l8vg 52 4 linked link VBN cord-301276-eer1l8vg 52 5 to to IN cord-301276-eer1l8vg 52 6 their -PRON- PRP$ cord-301276-eer1l8vg 52 7 having have VBG cord-301276-eer1l8vg 52 8 received receive VBN cord-301276-eer1l8vg 52 9 multiple multiple JJ cord-301276-eer1l8vg 52 10 vaccines vaccine NNS cord-301276-eer1l8vg 52 11 and and CC cord-301276-eer1l8vg 52 12 their -PRON- PRP$ cord-301276-eer1l8vg 52 13 tendency tendency NN cord-301276-eer1l8vg 52 14 to to TO cord-301276-eer1l8vg 52 15 develop develop VB cord-301276-eer1l8vg 52 16 several several JJ cord-301276-eer1l8vg 52 17 minor minor JJ cord-301276-eer1l8vg 52 18 infections infection NNS cord-301276-eer1l8vg 52 19 which which WDT cord-301276-eer1l8vg 52 20 may may MD cord-301276-eer1l8vg 52 21 have have VB cord-301276-eer1l8vg 52 22 served serve VBN cord-301276-eer1l8vg 52 23 to to TO cord-301276-eer1l8vg 52 24 activate activate VB cord-301276-eer1l8vg 52 25 their -PRON- PRP$ cord-301276-eer1l8vg 52 26 innate innate JJ cord-301276-eer1l8vg 52 27 immune immune JJ cord-301276-eer1l8vg 52 28 systems system NNS cord-301276-eer1l8vg 52 29 . . . cord-301276-eer1l8vg 53 1 There there EX cord-301276-eer1l8vg 53 2 also also RB cord-301276-eer1l8vg 53 3 are be VBP cord-301276-eer1l8vg 53 4 recent recent JJ cord-301276-eer1l8vg 53 5 claims claim NNS cord-301276-eer1l8vg 53 6 that that IN cord-301276-eer1l8vg 53 7 vaccination vaccination NN cord-301276-eer1l8vg 53 8 with with IN cord-301276-eer1l8vg 53 9 MMR MMR NNP cord-301276-eer1l8vg 53 10 vaccines vaccine NNS cord-301276-eer1l8vg 53 11 might may MD cord-301276-eer1l8vg 53 12 confer confer VB cord-301276-eer1l8vg 53 13 protection protection NN cord-301276-eer1l8vg 53 14 against against IN cord-301276-eer1l8vg 53 15 COVID-19 COVID-19 NNP cord-301276-eer1l8vg 53 16 as as IN cord-301276-eer1l8vg 53 17 it -PRON- PRP cord-301276-eer1l8vg 53 18 is be VBZ cord-301276-eer1l8vg 53 19 claimed claim VBN cord-301276-eer1l8vg 53 20 to to TO cord-301276-eer1l8vg 53 21 do do VB cord-301276-eer1l8vg 53 22 for for IN cord-301276-eer1l8vg 53 23 Rubella rubella NN cord-301276-eer1l8vg 53 24 because because IN cord-301276-eer1l8vg 53 25 of of IN cord-301276-eer1l8vg 53 26 cross cross NN cord-301276-eer1l8vg 53 27 reactivity reactivity NN cord-301276-eer1l8vg 53 28 ( ( -LRB- cord-301276-eer1l8vg 53 29 20 20 CD cord-301276-eer1l8vg 53 30 ) ) -RRB- cord-301276-eer1l8vg 53 31 . . . cord-301276-eer1l8vg 54 1 Other other JJ cord-301276-eer1l8vg 54 2 explanations explanation NNS cord-301276-eer1l8vg 54 3 for for IN cord-301276-eer1l8vg 54 4 the the DT cord-301276-eer1l8vg 54 5 apparent apparent JJ cord-301276-eer1l8vg 54 6 resistance resistance NN cord-301276-eer1l8vg 54 7 of of IN cord-301276-eer1l8vg 54 8 children child NNS cord-301276-eer1l8vg 54 9 to to TO cord-301276-eer1l8vg 54 10 clinically clinically RB cord-301276-eer1l8vg 54 11 evident evident JJ cord-301276-eer1l8vg 54 12 COVID-19 covid-19 JJ cord-301276-eer1l8vg 54 13 infection infection NN cord-301276-eer1l8vg 54 14 could could MD cord-301276-eer1l8vg 54 15 include include VB cord-301276-eer1l8vg 54 16 lower low JJR cord-301276-eer1l8vg 54 17 levels level NNS cord-301276-eer1l8vg 54 18 of of IN cord-301276-eer1l8vg 54 19 the the DT cord-301276-eer1l8vg 54 20 viral viral JJ cord-301276-eer1l8vg 54 21 entry entry NN cord-301276-eer1l8vg 54 22 receptor receptor NN cord-301276-eer1l8vg 54 23 and and CC cord-301276-eer1l8vg 54 24 the the DT cord-301276-eer1l8vg 54 25 tendency tendency NN cord-301276-eer1l8vg 54 26 of of IN cord-301276-eer1l8vg 54 27 children child NNS cord-301276-eer1l8vg 54 28 to to TO cord-301276-eer1l8vg 54 29 generate generate VB cord-301276-eer1l8vg 54 30 less less JJR cord-301276-eer1l8vg 54 31 tissue tissue NN cord-301276-eer1l8vg 54 32 damaging damage VBG cord-301276-eer1l8vg 54 33 so so RB cord-301276-eer1l8vg 54 34 - - HYPH cord-301276-eer1l8vg 54 35 called call VBN cord-301276-eer1l8vg 54 36 type type NN cord-301276-eer1l8vg 55 1 I -PRON- PRP cord-301276-eer1l8vg 55 2 inflammatory inflammatory JJ cord-301276-eer1l8vg 55 3 reactions reaction NNS cord-301276-eer1l8vg 55 4 to to IN cord-301276-eer1l8vg 55 5 antigens antigen NNS cord-301276-eer1l8vg 55 6 . . . cord-301276-eer1l8vg 56 1 In in IN cord-301276-eer1l8vg 56 2 conclusion conclusion NN cord-301276-eer1l8vg 56 3 , , , cord-301276-eer1l8vg 56 4 we -PRON- PRP cord-301276-eer1l8vg 56 5 surmise surmise VBP cord-301276-eer1l8vg 56 6 that that IN cord-301276-eer1l8vg 56 7 frequent frequent JJ cord-301276-eer1l8vg 56 8 exposure exposure NN cord-301276-eer1l8vg 56 9 of of IN cord-301276-eer1l8vg 56 10 individuals individual NNS cord-301276-eer1l8vg 56 11 to to IN cord-301276-eer1l8vg 56 12 natural natural JJ cord-301276-eer1l8vg 56 13 environmental environmental JJ cord-301276-eer1l8vg 56 14 microbes microbe NNS cord-301276-eer1l8vg 56 15 , , , cord-301276-eer1l8vg 56 16 live live VBP cord-301276-eer1l8vg 56 17 attenuated attenuated JJ cord-301276-eer1l8vg 56 18 vaccines vaccine NNS cord-301276-eer1l8vg 56 19 against against IN cord-301276-eer1l8vg 56 20 other other JJ cord-301276-eer1l8vg 56 21 viruses virus NNS cord-301276-eer1l8vg 56 22 or or CC cord-301276-eer1l8vg 56 23 bacteria bacteria NNS cord-301276-eer1l8vg 56 24 or or CC cord-301276-eer1l8vg 56 25 certain certain JJ cord-301276-eer1l8vg 56 26 natural natural JJ cord-301276-eer1l8vg 56 27 ligands ligand NNS cord-301276-eer1l8vg 56 28 such such JJ cord-301276-eer1l8vg 56 29 as as IN cord-301276-eer1l8vg 56 30 different different JJ cord-301276-eer1l8vg 56 31 types type NNS cord-301276-eer1l8vg 56 32 of of IN cord-301276-eer1l8vg 56 33 lectins lectin NNS cord-301276-eer1l8vg 56 34 and and CC cord-301276-eer1l8vg 56 35 saponins saponin NNS cord-301276-eer1l8vg 56 36 that that WDT cord-301276-eer1l8vg 56 37 can can MD cord-301276-eer1l8vg 56 38 stimulate stimulate VB cord-301276-eer1l8vg 56 39 innate innate JJ cord-301276-eer1l8vg 56 40 immune immune JJ cord-301276-eer1l8vg 56 41 receptors receptor NNS cord-301276-eer1l8vg 56 42 all all DT cord-301276-eer1l8vg 56 43 help help VBP cord-301276-eer1l8vg 56 44 to to TO cord-301276-eer1l8vg 56 45 reduce reduce VB cord-301276-eer1l8vg 56 46 the the DT cord-301276-eer1l8vg 56 47 clinical clinical JJ cord-301276-eer1l8vg 56 48 consequences consequence NNS cord-301276-eer1l8vg 56 49 of of IN cord-301276-eer1l8vg 56 50 COVID-19 covid-19 JJ cord-301276-eer1l8vg 56 51 infection infection NN cord-301276-eer1l8vg 56 52 . . . cord-301276-eer1l8vg 57 1 Moreover moreover RB cord-301276-eer1l8vg 57 2 , , , cord-301276-eer1l8vg 57 3 we -PRON- PRP cord-301276-eer1l8vg 57 4 await await VBP cord-301276-eer1l8vg 57 5 with with IN cord-301276-eer1l8vg 57 6 interest interest NN cord-301276-eer1l8vg 57 7 observations observation NNS cord-301276-eer1l8vg 57 8 comparing compare VBG cord-301276-eer1l8vg 57 9 the the DT cord-301276-eer1l8vg 57 10 outcome outcome NN cord-301276-eer1l8vg 57 11 of of IN cord-301276-eer1l8vg 57 12 COVID-19 covid-19 JJ cord-301276-eer1l8vg 57 13 infection infection NN cord-301276-eer1l8vg 57 14 in in IN cord-301276-eer1l8vg 57 15 adults adult NNS cord-301276-eer1l8vg 57 16 raised raise VBN cord-301276-eer1l8vg 57 17 as as IN cord-301276-eer1l8vg 57 18 infants infant NNS cord-301276-eer1l8vg 57 19 in in IN cord-301276-eer1l8vg 57 20 environments environment NNS cord-301276-eer1l8vg 57 21 that that WDT cord-301276-eer1l8vg 57 22 that that WDT cord-301276-eer1l8vg 57 23 support support VBP cord-301276-eer1l8vg 57 24 the the DT cord-301276-eer1l8vg 57 25 hygiene hygiene NN cord-301276-eer1l8vg 57 26 hypothesis hypothesis NN cord-301276-eer1l8vg 57 27 compared compare VBN cord-301276-eer1l8vg 57 28 to to IN cord-301276-eer1l8vg 57 29 those those DT cord-301276-eer1l8vg 57 30 raised raise VBN cord-301276-eer1l8vg 57 31 in in IN cord-301276-eer1l8vg 57 32 more more JJR cord-301276-eer1l8vg 57 33 hygienic hygienic JJ cord-301276-eer1l8vg 57 34 circumstances circumstance NNS cord-301276-eer1l8vg 57 35 . . . cord-301276-eer1l8vg 58 1 It -PRON- PRP cord-301276-eer1l8vg 58 2 seems seem VBZ cord-301276-eer1l8vg 58 3 relevant relevant JJ cord-301276-eer1l8vg 58 4 to to IN cord-301276-eer1l8vg 58 5 us -PRON- PRP cord-301276-eer1l8vg 58 6 to to TO cord-301276-eer1l8vg 58 7 employ employ VB cord-301276-eer1l8vg 58 8 innate innate JJ cord-301276-eer1l8vg 58 9 immune immune JJ cord-301276-eer1l8vg 58 10 activators activator NNS cord-301276-eer1l8vg 58 11 in in IN cord-301276-eer1l8vg 58 12 the the DT cord-301276-eer1l8vg 58 13 face face NN cord-301276-eer1l8vg 58 14 of of IN cord-301276-eer1l8vg 58 15 infection infection NN cord-301276-eer1l8vg 58 16 at at IN cord-301276-eer1l8vg 58 17 least least JJS cord-301276-eer1l8vg 58 18 until until IN cord-301276-eer1l8vg 58 19 such such JJ cord-301276-eer1l8vg 58 20 time time NN cord-301276-eer1l8vg 58 21 when when WRB cord-301276-eer1l8vg 58 22 effective effective JJ cord-301276-eer1l8vg 58 23 vaccines vaccine NNS cord-301276-eer1l8vg 58 24 are be VBP cord-301276-eer1l8vg 58 25 developed develop VBN cord-301276-eer1l8vg 58 26 . . . cord-301276-eer1l8vg 59 1 Could Could MD cord-301276-eer1l8vg 59 2 it -PRON- PRP cord-301276-eer1l8vg 59 3 also also RB cord-301276-eer1l8vg 59 4 be be VB cord-301276-eer1l8vg 59 5 that that DT cord-301276-eer1l8vg 59 6 constant constant JJ cord-301276-eer1l8vg 59 7 hand hand NN cord-301276-eer1l8vg 59 8 washing washing NN cord-301276-eer1l8vg 59 9 , , , cord-301276-eer1l8vg 59 10 taking take VBG cord-301276-eer1l8vg 59 11 antibiotics antibiotic NNS cord-301276-eer1l8vg 59 12 whenever whenever WRB cord-301276-eer1l8vg 59 13 we -PRON- PRP cord-301276-eer1l8vg 59 14 endure endure VBP cord-301276-eer1l8vg 59 15 minor minor JJ cord-301276-eer1l8vg 59 16 infections infection NNS cord-301276-eer1l8vg 59 17 and and CC cord-301276-eer1l8vg 59 18 over over IN cord-301276-eer1l8vg 59 19 - - HYPH cord-301276-eer1l8vg 59 20 sanitizing sanitize VBG cord-301276-eer1l8vg 59 21 our -PRON- PRP$ cord-301276-eer1l8vg 59 22 environs environ NNS cord-301276-eer1l8vg 59 23 is be VBZ cord-301276-eer1l8vg 59 24 not not RB cord-301276-eer1l8vg 59 25 necessarily necessarily RB cord-301276-eer1l8vg 59 26 such such PDT cord-301276-eer1l8vg 59 27 a a DT cord-301276-eer1l8vg 59 28 good good JJ cord-301276-eer1l8vg 59 29 idea idea NN cord-301276-eer1l8vg 59 30 ? ? . cord-301276-eer1l8vg 60 1 Herd herd NN cord-301276-eer1l8vg 60 2 immunity immunity NN cord-301276-eer1l8vg 60 3 : : : cord-301276-eer1l8vg 61 1 Understanding understand VBG cord-301276-eer1l8vg 61 2 COVID-19 COVID-19 NNP cord-301276-eer1l8vg 61 3 Coronavirus Coronavirus NNP cord-301276-eer1l8vg 61 4 disease disease NN cord-301276-eer1l8vg 61 5 ( ( -LRB- cord-301276-eer1l8vg 61 6 COVID-19 COVID-19 NNP cord-301276-eer1l8vg 61 7 ) ) -RRB- cord-301276-eer1l8vg 61 8 Situation situation NN cord-301276-eer1l8vg 61 9 report report NN cord-301276-eer1l8vg 61 10 Immunity immunity NN cord-301276-eer1l8vg 61 11 and and CC cord-301276-eer1l8vg 61 12 immunopathology immunopathology NN cord-301276-eer1l8vg 61 13 to to IN cord-301276-eer1l8vg 61 14 viruses virus NNS cord-301276-eer1l8vg 61 15 ; ; : cord-301276-eer1l8vg 61 16 What what WP cord-301276-eer1l8vg 61 17 decides decide VBZ cord-301276-eer1l8vg 61 18 the the DT cord-301276-eer1l8vg 61 19 outcome outcome NN cord-301276-eer1l8vg 61 20 ? ? . cord-301276-eer1l8vg 62 1 Genetic genetic JJ cord-301276-eer1l8vg 62 2 susceptibility susceptibility NN cord-301276-eer1l8vg 62 3 to to IN cord-301276-eer1l8vg 62 4 infectious infectious JJ cord-301276-eer1l8vg 62 5 diseases disease NNS cord-301276-eer1l8vg 62 6 : : : cord-301276-eer1l8vg 62 7 big big JJ cord-301276-eer1l8vg 62 8 is be VBZ cord-301276-eer1l8vg 62 9 beautiful beautiful JJ cord-301276-eer1l8vg 62 10 , , , cord-301276-eer1l8vg 62 11 but but CC cord-301276-eer1l8vg 62 12 will will MD cord-301276-eer1l8vg 62 13 bigger big JJR cord-301276-eer1l8vg 62 14 be be VB cord-301276-eer1l8vg 62 15 even even RB cord-301276-eer1l8vg 62 16 better well JJR cord-301276-eer1l8vg 62 17 ? ? . cord-301276-eer1l8vg 63 1 Human human JJ cord-301276-eer1l8vg 63 2 genetic genetic JJ cord-301276-eer1l8vg 63 3 determinants determinant NNS cord-301276-eer1l8vg 63 4 of of IN cord-301276-eer1l8vg 63 5 viral viral JJ cord-301276-eer1l8vg 63 6 diseases disease NNS cord-301276-eer1l8vg 63 7 Hay Hay NNP cord-301276-eer1l8vg 63 8 fever fever NN cord-301276-eer1l8vg 63 9 , , , cord-301276-eer1l8vg 63 10 hygiene hygiene NN cord-301276-eer1l8vg 63 11 , , , cord-301276-eer1l8vg 63 12 and and CC cord-301276-eer1l8vg 63 13 household household NN cord-301276-eer1l8vg 63 14 size size NN cord-301276-eer1l8vg 64 1 The the DT cord-301276-eer1l8vg 64 2 ' ' `` cord-301276-eer1l8vg 64 3 hygiene hygiene NN cord-301276-eer1l8vg 64 4 hypothesis hypothesis NN cord-301276-eer1l8vg 64 5 ' ' '' cord-301276-eer1l8vg 64 6 for for IN cord-301276-eer1l8vg 64 7 autoimmune autoimmune JJ cord-301276-eer1l8vg 64 8 and and CC cord-301276-eer1l8vg 64 9 allergic allergic JJ cord-301276-eer1l8vg 64 10 diseases disease NNS cord-301276-eer1l8vg 64 11 : : : cord-301276-eer1l8vg 64 12 an an DT cord-301276-eer1l8vg 64 13 update update NN cord-301276-eer1l8vg 64 14 Targeting target VBG cord-301276-eer1l8vg 64 15 the the DT cord-301276-eer1l8vg 64 16 human human JJ cord-301276-eer1l8vg 64 17 microbiome microbiome NN cord-301276-eer1l8vg 64 18 with with IN cord-301276-eer1l8vg 64 19 antibiotics antibiotic NNS cord-301276-eer1l8vg 64 20 , , , cord-301276-eer1l8vg 64 21 probiotics probiotic NNS cord-301276-eer1l8vg 64 22 , , , cord-301276-eer1l8vg 64 23 and and CC cord-301276-eer1l8vg 64 24 prebiotics prebiotic NNS cord-301276-eer1l8vg 64 25 : : : cord-301276-eer1l8vg 64 26 Gastroenterology Gastroenterology NNP cord-301276-eer1l8vg 64 27 enters enter VBZ cord-301276-eer1l8vg 64 28 the the DT cord-301276-eer1l8vg 64 29 metagenomics metagenomic NNS cord-301276-eer1l8vg 64 30 era era NN cord-301276-eer1l8vg 64 31 Situation situation NN cord-301276-eer1l8vg 64 32 report report NN cord-301276-eer1l8vg 65 1 COVID-19 COVID-19 NNP cord-301276-eer1l8vg 65 2 . . . cord-301276-eer1l8vg 66 1 27 27 CD cord-301276-eer1l8vg 66 2 th th XX cord-301276-eer1l8vg 66 3 Trained train VBN cord-301276-eer1l8vg 66 4 immunity immunity NN cord-301276-eer1l8vg 66 5 : : : cord-301276-eer1l8vg 66 6 A a DT cord-301276-eer1l8vg 66 7 program program NN cord-301276-eer1l8vg 66 8 of of IN cord-301276-eer1l8vg 66 9 innate innate JJ cord-301276-eer1l8vg 66 10 immune immune JJ cord-301276-eer1l8vg 66 11 memory memory NN cord-301276-eer1l8vg 66 12 in in IN cord-301276-eer1l8vg 66 13 health health NN cord-301276-eer1l8vg 66 14 and and CC cord-301276-eer1l8vg 66 15 disease disease NN cord-301276-eer1l8vg 66 16 BCG BCG NNP cord-301276-eer1l8vg 66 17 - - HYPH cord-301276-eer1l8vg 66 18 induced induce VBN cord-301276-eer1l8vg 66 19 trained train VBN cord-301276-eer1l8vg 66 20 immunity immunity NN cord-301276-eer1l8vg 66 21 : : : cord-301276-eer1l8vg 66 22 can can MD cord-301276-eer1l8vg 66 23 it -PRON- PRP cord-301276-eer1l8vg 66 24 offer offer VB cord-301276-eer1l8vg 66 25 protection protection NN cord-301276-eer1l8vg 66 26 against against IN cord-301276-eer1l8vg 66 27 COVID-19 COVID-19 NNP cord-301276-eer1l8vg 66 28 ? ? . cord-301276-eer1l8vg 67 1 Cellular cellular JJ cord-301276-eer1l8vg 67 2 resistance resistance NN cord-301276-eer1l8vg 67 3 to to IN cord-301276-eer1l8vg 67 4 infection infection NN cord-301276-eer1l8vg 67 5 Alterations alteration NNS cord-301276-eer1l8vg 67 6 of of IN cord-301276-eer1l8vg 67 7 macrophage macrophage NN cord-301276-eer1l8vg 67 8 functions function NNS cord-301276-eer1l8vg 67 9 by by IN cord-301276-eer1l8vg 67 10 mediators mediator NNS cord-301276-eer1l8vg 67 11 from from IN cord-301276-eer1l8vg 67 12 lymphocytes lymphocyte VBZ cord-301276-eer1l8vg 67 13 BCG BCG NNP cord-301276-eer1l8vg 67 14 vaccination vaccination NN cord-301276-eer1l8vg 67 15 protects protect VBZ cord-301276-eer1l8vg 67 16 against against IN cord-301276-eer1l8vg 67 17 experimental experimental JJ cord-301276-eer1l8vg 67 18 viral viral JJ cord-301276-eer1l8vg 67 19 infection infection NN cord-301276-eer1l8vg 67 20 in in IN cord-301276-eer1l8vg 67 21 humans human NNS cord-301276-eer1l8vg 67 22 through through IN cord-301276-eer1l8vg 67 23 the the DT cord-301276-eer1l8vg 67 24 induction induction NN cord-301276-eer1l8vg 67 25 of of IN cord-301276-eer1l8vg 67 26 cytokines cytokine NNS cord-301276-eer1l8vg 67 27 associated associate VBN cord-301276-eer1l8vg 67 28 with with IN cord-301276-eer1l8vg 67 29 trained train VBN cord-301276-eer1l8vg 67 30 immunity immunity NN cord-301276-eer1l8vg 68 1 The the DT cord-301276-eer1l8vg 68 2 case case NN cord-301276-eer1l8vg 68 3 for for IN cord-301276-eer1l8vg 68 4 a a DT cord-301276-eer1l8vg 68 5 stopgap stopgap JJ cord-301276-eer1l8vg 68 6 vaccine vaccine NN cord-301276-eer1l8vg 68 7 Promotion promotion NN cord-301276-eer1l8vg 68 8 of of IN cord-301276-eer1l8vg 68 9 tissue tissue NN cord-301276-eer1l8vg 68 10 inflammation inflammation NN cord-301276-eer1l8vg 68 11 by by IN cord-301276-eer1l8vg 68 12 the the DT cord-301276-eer1l8vg 68 13 immune immune JJ cord-301276-eer1l8vg 68 14 receptor receptor NN cord-301276-eer1l8vg 68 15 Tim-3 Tim-3 NNP cord-301276-eer1l8vg 68 16 expressed express VBD cord-301276-eer1l8vg 68 17 on on IN cord-301276-eer1l8vg 68 18 innate innate JJ cord-301276-eer1l8vg 68 19 immune immune JJ cord-301276-eer1l8vg 68 20 cells cell NNS cord-301276-eer1l8vg 68 21 Role role NN cord-301276-eer1l8vg 68 22 of of IN cord-301276-eer1l8vg 68 23 Tim-3 Tim-3 NNP cord-301276-eer1l8vg 68 24 / / SYM cord-301276-eer1l8vg 68 25 galectin-9 galectin-9 CD cord-301276-eer1l8vg 68 26 inhibitory inhibitory JJ cord-301276-eer1l8vg 68 27 interaction interaction NN cord-301276-eer1l8vg 68 28 in in IN cord-301276-eer1l8vg 68 29 viral viral RB cord-301276-eer1l8vg 68 30 - - HYPH cord-301276-eer1l8vg 68 31 induced induce VBN cord-301276-eer1l8vg 68 32 immunopathology immunopathology NN cord-301276-eer1l8vg 68 33 : : : cord-301276-eer1l8vg 68 34 shifting shift VBG cord-301276-eer1l8vg 68 35 the the DT cord-301276-eer1l8vg 68 36 balance balance NN cord-301276-eer1l8vg 68 37 toward toward IN cord-301276-eer1l8vg 68 38 regulators regulator NNS cord-301276-eer1l8vg 68 39 Homologous homologous JJ cord-301276-eer1l8vg 68 40 protein protein NN cord-301276-eer1l8vg 68 41 domains domain NNS cord-301276-eer1l8vg 68 42 in in IN cord-301276-eer1l8vg 68 43 SARS SARS NNP cord-301276-eer1l8vg 68 44 - - HYPH cord-301276-eer1l8vg 68 45 CoV-2 CoV-2 NNP cord-301276-eer1l8vg 68 46 and and CC cord-301276-eer1l8vg 68 47 measles measle NNS cord-301276-eer1l8vg 68 48 , , , cord-301276-eer1l8vg 68 49 mumps mumps NN cord-301276-eer1l8vg 68 50 and and CC cord-301276-eer1l8vg 68 51 rubella rubella NN cord-301276-eer1l8vg 68 52 viruses virus NNS cord-301276-eer1l8vg 68 53 : : : cord-301276-eer1l8vg 68 54 preliminary preliminary JJ cord-301276-eer1l8vg 68 55 evidence evidence NN cord-301276-eer1l8vg 68 56 that that IN cord-301276-eer1l8vg 68 57 MMR MMR NNP cord-301276-eer1l8vg 68 58 vaccine vaccine NN cord-301276-eer1l8vg 68 59 might may MD cord-301276-eer1l8vg 68 60 provide provide VB cord-301276-eer1l8vg 68 61 protection protection NN cord-301276-eer1l8vg 68 62 against against IN cord-301276-eer1l8vg 68 63 COVID-19 COVID-19 NNP cord-301276-eer1l8vg 68 64 BTR BTR NNP cord-301276-eer1l8vg 68 65 's 's POS cord-301276-eer1l8vg 68 66 viral viral JJ cord-301276-eer1l8vg 68 67 immunology immunology NN cord-301276-eer1l8vg 68 68 research research NN cord-301276-eer1l8vg 68 69 is be VBZ cord-301276-eer1l8vg 68 70 supported support VBN cord-301276-eer1l8vg 68 71 by by IN cord-301276-eer1l8vg 68 72 NIH NIH NNP cord-301276-eer1l8vg 68 73 grants grant NNS cord-301276-eer1l8vg 68 74 EY05093 EY05093 NNP cord-301276-eer1l8vg 68 75 and and CC cord-301276-eer1l8vg 68 76 AI142862 AI142862 NNP cord-301276-eer1l8vg 69 1 The the DT cord-301276-eer1l8vg 69 2 authors author NNS cord-301276-eer1l8vg 69 3 declare declare VBP cord-301276-eer1l8vg 69 4 no no DT cord-301276-eer1l8vg 69 5 conflict conflict NN cord-301276-eer1l8vg 69 6 of of IN cord-301276-eer1l8vg 69 7 financial financial JJ cord-301276-eer1l8vg 69 8 interest interest NN cord-301276-eer1l8vg 69 9 . . .